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Accession:CHEBI:59594 term browser browse the term
Definition:A polyallylamine cross-linked with epichlorohydrin and alkylated with 1-bromodecane and 6-bromohexyltrimethylammonium bromide. It is used as its hydrochloride as an orally administered bile acid sequestrant to reduce the amount of cholesterol and certain fatty substances in the blood.
Synonyms:xref: CAS:182815-43-6;   DrugBank:DB00930;   KEGG:D07743;   Patent:US5693675;   Patent:WO9534585

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colesevelam hydrochloride term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Crp C-reactive protein JBrowse link 13 91,080,448 91,081,358 RGD:6480464
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase JBrowse link 2 27,480,224 27,500,654 RGD:6480464
G Ldlr low density lipoprotein receptor JBrowse link 8 22,750,425 22,773,305 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19790
    role 19738
      application 19385
        pharmaceutical 19254
          drug 19254
            antilipemic drug 6388
              anticholesteremic drug 3894
                colesevelam 3
                  colesevelam hydrochloride 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19790
    subatomic particle 19788
      composite particle 19788
        hadron 19788
          baryon 19788
            nucleon 19788
              atomic nucleus 19788
                atom 19788
                  main group element atom 19674
                    main group molecular entity 19674
                      s-block molecular entity 19416
                        hydrogen molecular entity 19407
                          hydrides 18389
                            inorganic hydride 17221
                              pnictogen hydride 17184
                                nitrogen hydride 17018
                                  ammonium 8221
                                    ammonium ion derivative 8216
                                      ammonium compound 5091
                                        organoammonium salt 419
                                          quaternary ammonium salt 305
                                            colesevelam 3
                                              colesevelam hydrochloride 3
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.