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Term:clocortolone pivalate
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Accession:CHEBI:59583 term browser browse the term
Definition:The 21-O-pivalate ester of clocortolone. It is used for the relief of inflammatory and pruritic (itching) skin disorders.
Synonyms:exact_synonym: 9-chloro-6alpha-fluoro-11beta-hydroxy-16alpha-methyl-3,20-dioxopregna-1,4-dien-21-yl 2,2-dimethylpropanoate
 related_synonym: 9-chloro-6alpha-fluoro-11beta,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 21-pivalate;   Formula=C27H36ClFO5;   InChI=1S/C27H36ClFO5/c1-14-9-16-17-11-19(29)18-10-15(30)7-8-26(18,6)27(17,28)21(32)12-25(16,5)22(14)20(31)13-34-23(33)24(2,3)4/h7-8,10,14,16-17,19,21-22,32H,9,11-13H2,1-6H3/t14-,16+,17+,19+,21+,22-,25+,26+,27+/m1/s1;   InChIKey=SXYZQZLHAIHKKY-GSTUPEFVSA-N;   SMILES=[H][C@@]12C[C@@H](C)[C@H](C(=O)COC(=O)C(C)(C)C)[C@@]1(C)C[C@H](O)[C@@]1(Cl)[C@@]2([H])C[C@H](F)C2=CC(=O)C=C[C@]12C;   clocortolone 21-pivalate
 xref: CAS:34097-16-0;   DrugBank:DB00838;   Drug_Central:4606;   KEGG:D02287

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  CHEBI ontology 19758
    role 19705
      application 19359
        anti-inflammatory agent 14958
          anti-inflammatory drug 13610
            clocortolone pivalate 0
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  CHEBI ontology 19758
    subatomic particle 19756
      composite particle 19756
        hadron 19756
          baryon 19756
            nucleon 19756
              atomic nucleus 19756
                atom 19756
                  main group element atom 19641
                    p-block element atom 19641
                      carbon group element atom 19532
                        carbon atom 19521
                          organic molecular entity 19521
                            organic group 18428
                              organic divalent group 18419
                                organodiyl group 18419
                                  carbonyl group 18309
                                    carbonyl compound 18309
                                      carboxylic acid 17978
                                        monocarboxylic acid 17287
                                          fatty acid 15827
                                            saturated fatty acid 15793
                                              branched-chain saturated fatty acid 14752
                                                pivalic acid 1
                                                  pivalate ester 1
                                                    clocortolone pivalate 0
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