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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:medium-chain fatty acid anion
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Accession:CHEBI:59558 term browser browse the term
Definition:A fatty acid anion resulting from the deprotonation of the carboxylic acid moiety of a medium-chain fatty acid.
Synonyms:related_synonym: Formula=CO2R;   MCFA anion;   MCFA anions;   SMILES=[O-]C([*])=O;   a medium chain fatty acid;   medium-chain FA anion;   medium-chain FA anions;   medium-chain fatty acid anions
 cyclic_relationship: is_conjugate_base_of CHEBI:59554


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6-aminohexanoate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin decreases expression ISO Aminocaproic Acid results in decreased expression of A2M protein CTD PMID:11304663 NCBI chr 4:154,309,426...154,359,138
Ensembl chr 4:154,309,426...154,359,137
Ensembl chr 4:154,309,426...154,359,137
JBrowse link
G Folh1 folate hydrolase 1 multiple interactions ISO [2-(3-(1,3-dicarboxypropyl)ureido)pentanedioic acid binds to Aminocaproic Acid binds to 1-(1,3-carboxypropyl)-4,7-carboxymethyl-1,4,7-triazacyclononane binds to Valerates binds to bombesin (7-14) binds to Copper] inhibits the reaction [isospaglumic acid binds to FOLH1 protein] CTD PMID:24508213 NCBI chr 1:150,323,768...150,395,415
Ensembl chr 1:150,323,768...150,395,415
JBrowse link
G Grpr gastrin releasing peptide receptor multiple interactions ISO [2-(3-(1,3-dicarboxypropyl)ureido)pentanedioic acid binds to Aminocaproic Acid binds to 1-(1,3-carboxypropyl)-4,7-carboxymethyl-1,4,7-triazacyclononane binds to Valerates binds to bombesin (7-14) binds to Copper] inhibits the reaction [bombesin, Tyr(4)- binds to GRPR protein] CTD PMID:24508213 NCBI chr  X:32,746,259...32,786,266
Ensembl chr  X:32,745,873...32,786,359
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO Aminocaproic Acid inhibits the reaction [PLG protein results in increased phosphorylation of MAPK1 protein] CTD PMID:17482686 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO Aminocaproic Acid inhibits the reaction [PLG protein results in increased phosphorylation of MAPK3 protein] CTD PMID:17482686 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Plg plasminogen multiple interactions ISO Aminocaproic Acid inhibits the reaction [PLG protein results in increased phosphorylation of MAPK1 protein]; Aminocaproic Acid inhibits the reaction [PLG protein results in increased phosphorylation of MAPK3 protein] CTD PMID:17482686 NCBI chr 1:48,521,828...48,563,895
Ensembl chr 1:48,521,772...48,563,776
JBrowse link
G Serpinc1 serpin family C member 1 increases expression ISO Aminocaproic Acid results in increased expression of SERPINC1 protein CTD PMID:11304663 NCBI chr13:78,806,107...78,820,375
Ensembl chr13:78,805,347...78,833,192
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19781
    chemical entity 19781
      atom 19779
        nonmetal atom 19659
          carbon atom 19578
            organic molecular entity 19578
              lipid 17485
                fatty acid anion 103
                  medium-chain fatty acid anion 7
                    (2E)-oct-2-enoate 0
                    (3E,5Z)-dodecadienoate 0
                    (3Z,5E)-dodecadienoate 0
                    (E)-dodec-2-enoate 0
                    (S)-citronellate 0
                    10-hydroxylaurate 0
                    11-hydroxylaurate + 0
                    12-oxododecanoate 0
                    2,3-dihydroxydodecanoate 0
                    2,6-dimethylheptanoate 0
                    2-hydroxydecanoate 0
                    2-hydroxydodec-2-enoate 0
                    2-hydroxyhexanoate 0
                    3,12-dihydroxylaurate 0
                    3-hydroxydecanoate 0
                    3-hydroxylaurate 0
                    3-methylundecanoate 0
                    4,8-dimethylnonanoate 0
                    4-hydroxy-2-oxohexanoate + 0
                    5-hydroxyhexanoate 0
                    5-oxohexanoate 0
                    6-hydroxyhexanoate 0
                    7-hydroxylaurate 0
                    8-hydroxylaurate 0
                    9-hydroxylaurate 0
                    9-oxononanoate 0
                    cis-obtusilate 0
                    dec-9-enoate 0
                    decanoate + 0
                    dodecanoate + 0
                    dodecenoate + 0
                    fatty acid anion 6:0 + 7
                    heptanoate + 0
                    hexadienoate + 0
                    hydroxyoctanoate + 0
                    isocaproate 0
                    nonanoate + 0
                    octadienoate + 0
                    octatrienoate + 0
                    undecanoate 0
                    undecenoate + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19781
    subatomic particle 19779
      composite particle 19779
        hadron 19779
          baryon 19779
            nucleon 19779
              atomic nucleus 19779
                atom 19779
                  main group element atom 19669
                    p-block element atom 19669
                      chalcogen 19401
                        chalcogen molecular entity 19401
                          oxygen molecular entity 19364
                            oxide 11713
                              oxoanion 8883
                                carboxylic acid anion 2394
                                  monocarboxylic acid anion 1499
                                    fatty acid anion 103
                                      medium-chain fatty acid anion 7
                                        (2E)-oct-2-enoate 0
                                        (3E,5Z)-dodecadienoate 0
                                        (3Z,5E)-dodecadienoate 0
                                        (E)-dodec-2-enoate 0
                                        (S)-citronellate 0
                                        10-hydroxylaurate 0
                                        11-hydroxylaurate + 0
                                        12-oxododecanoate 0
                                        2,3-dihydroxydodecanoate 0
                                        2,6-dimethylheptanoate 0
                                        2-hydroxydecanoate 0
                                        2-hydroxydodec-2-enoate 0
                                        2-hydroxyhexanoate 0
                                        3,12-dihydroxylaurate 0
                                        3-hydroxydecanoate 0
                                        3-hydroxylaurate 0
                                        3-methylundecanoate 0
                                        4,8-dimethylnonanoate 0
                                        4-hydroxy-2-oxohexanoate + 0
                                        5-hydroxyhexanoate 0
                                        5-oxohexanoate 0
                                        6-hydroxyhexanoate 0
                                        7-hydroxylaurate 0
                                        8-hydroxylaurate 0
                                        9-hydroxylaurate 0
                                        9-oxononanoate 0
                                        cis-obtusilate 0
                                        dec-9-enoate 0
                                        decanoate + 0
                                        dodecanoate + 0
                                        dodecenoate + 0
                                        fatty acid anion 6:0 + 7
                                        heptanoate + 0
                                        hexadienoate + 0
                                        hydroxyoctanoate + 0
                                        isocaproate 0
                                        nonanoate + 0
                                        octadienoate + 0
                                        octatrienoate + 0
                                        undecanoate 0
                                        undecenoate + 0
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