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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:phosphoantigen
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Accession:CHEBI:59544 term browser browse the term
Definition:Any antigen that is a phosphorylated microbial metabolite which activates an immune response in humans.
Synonyms:related_synonym: phosphoantigens


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ethyl dihydrogen phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ins2 insulin II multiple interactions EXP [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased abundance of monoethyl phosphate analog CTD PMID:26820058 NCBI chr 7:142,232,393...142,233,463
Ensembl chr 7:142,232,393...142,297,118 		JBrowse link
isopentenyl diphosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccr5 C-C motif chemokine receptor 5 decreases expression ISO isopentenyl pyrophosphate results in decreased expression of CCR5 protein CTD PMID:11994442 NCBI chr 9:123,921,557...123,934,153
Ensembl chr 9:123,921,580...123,947,736 		JBrowse link
G Fdps farnesyl diphosphate synthetase multiple interactions ISO [zoledronic acid results in decreased activity of FDPS protein] which results in increased abundance of isopentenyl pyrophosphate CTD PMID:19699819 NCBI chr 3:89,000,895...89,009,274
Ensembl chr 3:89,000,895...89,009,266 		JBrowse link
G Fgf9 fibroblast growth factor 9 increases expression ISO isopentenyl pyrophosphate results in increased expression of FGF9 mRNA; isopentenyl pyrophosphate results in increased expression of FGF9 protein CTD PMID:14704367 NCBI chr14:58,308,543...58,350,311
Ensembl chr14:58,308,004...58,350,177 		JBrowse link
G Ifng interferon gamma multiple interactions
increases expression		 ISO Calcitriol inhibits the reaction [isopentenyl pyrophosphate results in increased expression of IFNG protein] CTD PMID:15879110 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797 		JBrowse link
G Il2ra interleukin 2 receptor, alpha chain multiple interactions
increases expression		 ISO Calcitriol inhibits the reaction [isopentenyl pyrophosphate results in increased expression of IL2RA protein] CTD PMID:15879110 NCBI chr 2:11,647,603...11,698,005
Ensembl chr 2:11,647,618...11,698,004 		JBrowse link
G Mvk mevalonate kinase decreases activity
multiple interactions		 ISO isopentenyl pyrophosphate results in decreased activity of MVK protein
isopentenyl pyrophosphate inhibits the reaction [MVK protein results in increased hydrolysis of Adenosine Triphosphate]; isopentenyl pyrophosphate inhibits the reaction [MVK protein results in increased phosphorylation of Mevalonic Acid]		 CTD PMID:9392419 NCBI chr 5:114,582,324...114,598,652
Ensembl chr 5:114,582,330...114,598,652 		JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 multiple interactions EXP isopentenyl pyrophosphate inhibits the reaction [cinnamaldehyde results in increased activity of TRPA1 protein] CTD PMID:21353389 NCBI chr 1:14,942,868...14,989,086
Ensembl chr 1:14,942,872...14,989,086 		JBrowse link
G Trpv3 transient receptor potential cation channel, subfamily V, member 3 multiple interactions ISO isopentenyl pyrophosphate inhibits the reaction [Camphor results in increased activity of TRPV3 protein] CTD PMID:21353389 NCBI chr11:73,158,315...73,191,194
Ensembl chr11:73,158,214...73,191,189 		JBrowse link
G Vdr vitamin D (1,25-dihydroxyvitamin D3) receptor multiple interactions
increases expression		 ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [isopentenyl pyrophosphate results in increased expression of VDR protein]; Go 6976 inhibits the reaction [isopentenyl pyrophosphate results in increased expression of VDR protein]; U 0126 inhibits the reaction [isopentenyl pyrophosphate results in increased expression of VDR protein] CTD PMID:15879110 NCBI chr15:97,752,308...97,806,177
Ensembl chr15:97,752,306...97,808,511 		JBrowse link
methyl dihydrogen phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ins2 insulin II multiple interactions EXP [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased abundance of methylphosphate analog CTD PMID:26820058 NCBI chr 7:142,232,393...142,233,463
Ensembl chr 7:142,232,393...142,297,118 		JBrowse link
prenyl diphosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il12rb1 interleukin 12 receptor, beta 1 increases expression ISO 3,3-dimethylallyl pyrophosphate results in increased expression of IL12RB1 protein CTD PMID:12932289 NCBI chr 8:71,261,005...71,276,186
Ensembl chr 8:71,261,093...71,274,068 		JBrowse link
G Mvk mevalonate kinase multiple interactions
decreases activity		 ISO 3,3-dimethylallyl pyrophosphate inhibits the reaction [MVK protein results in increased hydrolysis of Adenosine Triphosphate]; 3,3-dimethylallyl pyrophosphate inhibits the reaction [MVK protein results in increased phosphorylation of Mevalonic Acid]
3,3-dimethylallyl pyrophosphate results in decreased activity of MVK protein		 CTD PMID:9392419 NCBI chr 5:114,582,324...114,598,652
Ensembl chr 5:114,582,330...114,598,652 		JBrowse link
G Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b increases expression ISO 3,3-dimethylallyl pyrophosphate results in increased expression of TNFRSF1B protein CTD PMID:12932289 NCBI chr 4:144,938,938...144,973,453
Ensembl chr 4:144,940,033...144,973,440 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22178
    role 22194
      biological role 22162
        antigen 133
          phosphoantigen 12
            (2E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate 0
            (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate(3-) 0
            bromohydrin pyrophosphate 0
            ethyl dihydrogen phosphate + 1
            ethyl hydrogen phosphate(1-) 0
            ethyl phosphate(2-) 0
            isopentenyl diphosphate 9
            isopentenyl diphosphate(3-) 0
            isopropyl dihydrogen phosphate 0
            methyl dihydrogen phosphate 1
            methyl phosphate(2-) 0
            prenyl diphosphate 3
            prenyl diphosphate(3-) 0
paths to the root