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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:iodoquinol
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Accession:CHEBI:5950 term browser browse the term
Definition:A monohydroxyquinoline that is quinolin-8-ol in which the hydrogens at positions 5 and 7 are replaced by iodine. It is considered the drug of choice for treating asymptomatic or moderate forms of amoebiasis.
Synonyms:exact_synonym: 5,7-diiodoquinolin-8-ol
 related_synonym: 5,7-diiodo-8-hydroxyquinoline;   5,7-diiodo-8-quinolinol;   8-hydroxy-5,7-diiodoquinoline;   Diamoebin;   Diodoquine;   Diodoxylin;   Diquinol;   Direxiode;   Dyodin;   Embequin;   Enterosept;   Floraquin;   Fluoraquin;   Formula=C9H5I2NO;   InChI=1S/C9H5I2NO/c10-6-4-7(11)9(13)8-5(6)2-1-3-12-8/h1-4,13H;   InChIKey=UXZFQZANDVDGMM-UHFFFAOYSA-N;   Ioquin;   Lanodoxin;   Moebiquin;   Panaquin;   Quinadome;   Rafamebin;   SMILES=OC1=C2N=CC=CC2=C(I)C=C1I;   SS 578;   Searlequin;   Sebaquin;   Yodoxin;   Zoaquin;   di-iodohydroxyquinoline;   diiodohidroxiquinoleina;   diiodohydroxyquin;   diiodohydroxyquinoleine;   diiodohydroxyquinoline;   diiodohydroxyquinolinum;   diiodoquin;   diiodoquinol
 xref: CAS:83-73-8;   Chemspider:3597;   DrugBank:DB09115;   Drug_Central:1457;   KEGG:C07636;   KEGG:D00581;   LINCS:LSM-25652
 xref_mesh: MESH:D004103
 xref: PMID:1090898;   PMID:122845;   PMID:126030;   PMID:13513741;   PMID:13568180;   PMID:13867524;   PMID:14493155;   PMID:19055171;   PMID:2146587;   PMID:22650;   PMID:24035940;   PMID:24533282;   PMID:2493578;   PMID:27449410;   PMID:29438107;   PMID:30895611;   PMID:3104778;   PMID:31141575;   PMID:321481;   PMID:32253206;   PMID:32473310;   PMID:329460;   PMID:33052959;   PMID:4276320;   PMID:4608821;   PMID:4874115;   PMID:4893942;   PMID:6783511;   PMID:8067755;   PMID:8433407;   PMID:9408854;   Reaxys:153639;   Wikipedia:Diiodohydroxyquinoline


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iodoquinol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO Iodoquinol inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
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Term Annotations click to browse term
  CHEBI ontology 19821
    role 19769
      biological role 19769
        antimicrobial agent 17408
          antibacterial agent 13571
            iodoquinol 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    p-block element atom 19716
                      carbon group element atom 19640
                        carbon atom 19630
                          organic molecular entity 19630
                            organic molecule 19569
                              organic cyclic compound 19360
                                organic heterocyclic compound 18591
                                  organonitrogen heterocyclic compound 17643
                                    quinolines 2591
                                      hydroxyquinoline 307
                                        monohydroxyquinoline 307
                                          iodoquinol 1
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