Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:iodoquinol
go back to main search page
Accession:CHEBI:5950 term browser browse the term
Definition:A monohydroxyquinoline that is quinolin-8-ol in which the hydrogens at positions 5 and 7 are replaced by iodine. It is considered the drug of choice for treating asymptomatic or moderate forms of amoebiasis.
Synonyms:exact_synonym: 5,7-diiodoquinolin-8-ol
 related_synonym: 5,7-diiodo-8-hydroxyquinoline;   5,7-diiodo-8-quinolinol;   8-hydroxy-5,7-diiodoquinoline;   Diamoebin;   Diodoquine;   Diodoxylin;   Diquinol;   Direxiode;   Dyodin;   Embequin;   Enterosept;   Floraquin;   Fluoraquin;   Formula=C9H5I2NO;   InChI=1S/C9H5I2NO/c10-6-4-7(11)9(13)8-5(6)2-1-3-12-8/h1-4,13H;   InChIKey=UXZFQZANDVDGMM-UHFFFAOYSA-N;   Ioquin;   Lanodoxin;   Moebiquin;   Panaquin;   Quinadome;   Rafamebin;   SMILES=OC1=C2N=CC=CC2=C(I)C=C1I;   SS 578;   Searlequin;   Sebaquin;   Yodoxin;   Zoaquin;   di-iodohydroxyquinoline;   diiodohidroxiquinoleina;   diiodohydroxyquin;   diiodohydroxyquinoleine;   diiodohydroxyquinoline;   diiodohydroxyquinolinum;   diiodoquin;   diiodoquinol
 xref: CAS:83-73-8;   Chemspider:3597;   DrugBank:DB09115;   Drug_Central:1457;   KEGG:C07636;   KEGG:D00581;   LINCS:LSM-25652
 xref_mesh: MESH:D004103
 xref: PMID:1090898;   PMID:122845;   PMID:126030;   PMID:13513741;   PMID:13568180;   PMID:13867524;   PMID:14493155;   PMID:19055171;   PMID:2146587;   PMID:22650;   PMID:24035940;   PMID:24533282;   PMID:2493578;   PMID:27449410;   PMID:29438107;   PMID:30895611;   PMID:3104778;   PMID:31141575;   PMID:321481;   PMID:32253206;   PMID:32473310;   PMID:329460;   PMID:33052959;   PMID:4276320;   PMID:4608821;   PMID:4874115;   PMID:4893942;   PMID:6783511;   PMID:8067755;   PMID:8433407;   PMID:9408854;   Reaxys:153639;   Wikipedia:Diiodohydroxyquinoline



show annotations for term's descendants           Sort by:
iodoquinol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO Iodoquinol inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19740
    role 19713
      biological role 19711
        antimicrobial agent 17880
          antibacterial agent 14569
            iodoquinol 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19740
    subatomic particle 19738
      composite particle 19738
        hadron 19738
          baryon 19738
            nucleon 19738
              atomic nucleus 19738
                atom 19738
                  main group element atom 19686
                    p-block element atom 19686
                      carbon group element atom 19631
                        carbon atom 19627
                          organic molecular entity 19627
                            organic molecule 19587
                              organic cyclic compound 19393
                                organic heterocyclic compound 18766
                                  organonitrogen heterocyclic compound 17995
                                    quinolines 2630
                                      hydroxyquinoline 320
                                        monohydroxyquinoline 317
                                          iodoquinol 1
paths to the root