CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: scalarane sesterterpenoid
Accession: CHEBI:59370
browse the term
Definition: A class of sesterterpenoids based on the structure of the hypothetical sesterterpene scalarane.
G
Il1b
interleukin 1 beta
multiple interactions
ISO
scalaradial inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]; scalaradial inhibits the reaction [IL1B protein results in increased expression of TNF protein]; scalaradial inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]
CTD
PMID:7575673
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
G
Mpo
myeloperoxidase
multiple interactions
ISO
scalaradial inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]
CTD
PMID:8113982
NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819
G
Ptgs2
prostaglandin-endoperoxide synthase 2
multiple interactions
ISO
scalaradial inhibits the reaction [[Lipopolysaccharides results in increased expression of and results in increased activity of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone]; scalaradial inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]; scalaradial inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased activity of PTGS2 protein]
CTD
PMID:7575673
NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
G
Tnf
tumor necrosis factor
multiple interactions
ISO
scalaradial inhibits the reaction [IL1B protein results in increased expression of TNF protein]; scalaradial inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]
CTD
PMID:7575673
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
G
Adh1
alcohol dehydrogenase 1C (class I), gamma polypeptide
multiple interactions
ISO
taraxerone promotes the reaction [Ethanol results in increased expression of ADH1 mRNA]
CTD
PMID:22554647
NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892
G
Aldh2
aldehyde dehydrogenase 2 family member
multiple interactions
ISO
taraxerone promotes the reaction [Ethanol results in increased expression of ALDH2 mRNA]
CTD
PMID:22554647
NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
G
Cat
catalase
multiple interactions
ISO
taraxerone inhibits the reaction [Ethanol results in decreased expression of CAT protein]
CTD
PMID:22554647
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all
Path 1
CHEBI ontology
20056
chemical entity
20055
atom
20054
nonmetal atom
19945
carbon atom
19875
organic molecular entity
19875
isoprenoid
13624
terpenoid
13273
sesterterpenoid
8
scalarane sesterterpenoid
7
(+)-Desoxyscalarin
0
(+)-Scalarin
0
(2R,7R,8R,9R,10S,20S)-7,8,9,19-tetrahydroxy-6,17-bis(hydroxymethyl)-2,6,10,17-tetramethylhexacyclo[12.8.1.01,14.02,11.05,10.015,20]tricos-12-ene-20-carboxylic acid
0
12-O-acetyl-16-O-deacetyl-16-epi-scalarobutenolide
0
12-O-acetyl-16-O-methylhyrtiolide
0
12-O-deacetyl-12-epi-19-deoxy-21-hydroxyscalarin
0
12-O-deacetyl-19-O-methyl-12-epi-deoxoscalarin
0
12-deacetoxy-21-acetoxyscalarin
0
12-epi-19-O-methyldeoxoscalarin
0
12-epi-19-O-methylscalarin
0
12-epi-Scalaradial
0
12-epi-deoxoscalarin +
0
12-epi-scalarin +
0
12alpha-Deoxoscalarin
0
14betaH-scalarane-17alpha-19-diol
0
16-Deacetoxy-12-epi-scalarafuranacetate
0
16-O-deacetyl-16-epi-scalarolbutenolide
0
18-episcalar-17(25)-en-19-ol
0
23-acetoxy-12-O-deacetyl-12-epi-deoxoscalarin
0
23-acetoxy-12-epi-deoxoscalarin +
0
Acinospesigenin A
0
Myricolal
0
Sebiferenic acid
0
hyrtial
0
rel-(3R,4R,5aS,5bR,7aS,11aS,11bR,13R,13aS)-3-hydroxy-4-methoxy-5b,8,8,11a,13a-pentamethyl-1-oxo-1,3,4,5,5a,5b,6,7,7a,8,9,10,11,11a,11b,12,13,13a-octadecahydrochryseno[2,1-c]furan-13-yl acetate
0
scalar-17(25)-en-19-ol
0
scalaradial
4
scalarane-17alpha-19-diol
0
scalarin
0
sesterstatin 1
0
sesterstatin 2
0
sesterstatin 3
0
sesterstatin 7
0
taraxerone
3
Path 2
CHEBI ontology
20056
subatomic particle
20054
composite particle
20054
hadron
20054
baryon
20054
nucleon
20054
atomic nucleus
20054
atom
20054
main group element atom
19956
main group molecular entity
19956
s-block molecular entity
19752
hydrogen molecular entity
19745
hydrides
19114
organic hydride
18653
organic fundamental parent
18653
hydrocarbon
18389
terpene
13624
sesterterpene
18
sesterterpenoid
8
scalarane sesterterpenoid
7
(+)-Desoxyscalarin
0
(+)-Scalarin
0
(2R,7R,8R,9R,10S,20S)-7,8,9,19-tetrahydroxy-6,17-bis(hydroxymethyl)-2,6,10,17-tetramethylhexacyclo[12.8.1.01,14.02,11.05,10.015,20]tricos-12-ene-20-carboxylic acid
0
12-O-acetyl-16-O-deacetyl-16-epi-scalarobutenolide
0
12-O-acetyl-16-O-methylhyrtiolide
0
12-O-deacetyl-12-epi-19-deoxy-21-hydroxyscalarin
0
12-O-deacetyl-19-O-methyl-12-epi-deoxoscalarin
0
12-deacetoxy-21-acetoxyscalarin
0
12-epi-19-O-methyldeoxoscalarin
0
12-epi-19-O-methylscalarin
0
12-epi-Scalaradial
0
12-epi-deoxoscalarin +
0
12-epi-scalarin +
0
12alpha-Deoxoscalarin
0
14betaH-scalarane-17alpha-19-diol
0
16-Deacetoxy-12-epi-scalarafuranacetate
0
16-O-deacetyl-16-epi-scalarolbutenolide
0
18-episcalar-17(25)-en-19-ol
0
23-acetoxy-12-O-deacetyl-12-epi-deoxoscalarin
0
23-acetoxy-12-epi-deoxoscalarin +
0
Acinospesigenin A
0
Myricolal
0
Sebiferenic acid
0
hyrtial
0
rel-(3R,4R,5aS,5bR,7aS,11aS,11bR,13R,13aS)-3-hydroxy-4-methoxy-5b,8,8,11a,13a-pentamethyl-1-oxo-1,3,4,5,5a,5b,6,7,7a,8,9,10,11,11a,11b,12,13,13a-octadecahydrochryseno[2,1-c]furan-13-yl acetate
0
scalar-17(25)-en-19-ol
0
scalaradial
4
scalarane-17alpha-19-diol
0
scalarin
0
sesterstatin 1
0
sesterstatin 2
0
sesterstatin 3
0
sesterstatin 7
0
taraxerone
3