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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:acetate salt
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Accession:CHEBI:59230 term browser browse the term
Definition:Any salt prepared using acetic acid as the acid component.
Synonyms:related_synonym: acetate salts


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ammonium acetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase increases activity ISO ammonium acetate results in increased activity of ADA protein CTD PMID:19900420 NCBI chr 2:163,726,571...163,750,239
Ensembl chr 2:163,726,584...163,750,239
JBrowse link
G Ampd2 adenosine monophosphate deaminase 2 increases activity ISO ammonium acetate results in increased activity of AMPD2 protein CTD PMID:19900420 NCBI chr 3:108,074,059...108,086,687
Ensembl chr 3:108,074,062...108,086,651
JBrowse link
G Ampd3 adenosine monophosphate deaminase 3 increases activity ISO ammonium acetate results in increased activity of AMPD3 protein CTD PMID:19900420 NCBI chr 7:110,767,790...110,812,409
Ensembl chr 7:110,768,206...110,812,405
JBrowse link
G Asl argininosuccinate lyase increases activity ISO ammonium acetate results in increased activity of ASL protein CTD PMID:16009439 NCBI chr 5:130,011,258...130,024,381
Ensembl chr 5:130,011,258...130,029,247
JBrowse link
G Ass1 argininosuccinate synthetase 1 increases activity ISO ammonium acetate results in increased activity of ASS1 protein CTD PMID:16009439 NCBI chr 2:31,470,270...31,520,670
Ensembl chr 2:31,470,207...31,520,672
JBrowse link
G Cat catalase increases activity
decreases activity
multiple interactions
ISO ammonium acetate results in increased activity of CAT protein
ammonium acetate results in decreased activity of CAT protein
Dizocilpine Maleate inhibits the reaction [ammonium acetate results in decreased activity of CAT protein]
CTD PMID:12885441, PMID:15945352 NCBI chr 2:103,453,904...103,485,153
Ensembl chr 2:103,453,849...103,485,160
JBrowse link
G Grin2a glutamate receptor, ionotropic, NMDA2A (epsilon 1) multiple interactions
decreases expression
ISO Allopurinol inhibits the reaction [ammonium acetate results in decreased expression of GRIN2A protein] CTD PMID:20084674 NCBI chr16:9,567,901...9,996,083
Ensembl chr16:9,567,898...9,995,560
JBrowse link
G Grin2b glutamate receptor, ionotropic, NMDA2B (epsilon 2) decreases expression ISO ammonium acetate results in decreased expression of GRIN2B protein CTD PMID:20084674 NCBI chr 6:135,713,221...136,173,615
Ensembl chr 6:135,713,233...136,173,511
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO ammonium acetate results in increased expression of HMOX1 protein CTD PMID:12420312 NCBI chr 8:75,093,618...75,100,593
Ensembl chr 8:75,093,621...75,100,589
JBrowse link
G Maoa monoamine oxidase A increases activity
multiple interactions
ISO ammonium acetate results in increased activity of MAOA protein
Dizocilpine Maleate inhibits the reaction [ammonium acetate results in increased activity of MAOA protein]
CTD PMID:12885441 NCBI chr  X:16,619,698...16,687,812
Ensembl chr  X:16,619,698...16,687,818
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 increases expression
multiple interactions
ISO ammonium acetate results in increased expression of PARP1 protein
Cycloheximide inhibits the reaction [ammonium acetate results in increased expression of PARP1 protein]; Dizocilpine Maleate inhibits the reaction [ammonium acetate results in increased expression of PARP1 protein]
CTD PMID:15147502 NCBI chr 1:180,568,891...180,600,999
Ensembl chr 1:180,568,924...180,601,254
JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial decreases activity
multiple interactions
ISO ammonium acetate results in decreased activity of SOD2 protein
Dizocilpine Maleate inhibits the reaction [ammonium acetate results in decreased activity of SOD2 protein]
CTD PMID:12885441 NCBI chr17:13,007,839...13,018,119
Ensembl chr17:13,006,846...13,040,063
JBrowse link
G Xdh xanthine dehydrogenase affects activity
multiple interactions
ISO ammonium acetate affects the activity of XDH protein
Dizocilpine Maleate inhibits the reaction [ammonium acetate affects the activity of XDH protein]
CTD PMID:12885441 NCBI chr17:73,883,895...73,950,397
Ensembl chr17:73,883,895...73,950,196
JBrowse link
cobalt(II) acetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hif1a hypoxia inducible factor 1, alpha subunit increases expression ISO cobalt(II) acetate results in increased expression of HIF1A protein CTD PMID:16357179 NCBI chr12:73,901,324...73,947,554
Ensembl chr12:73,901,375...73,947,530
JBrowse link
lead tetraacetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta (A4) precursor protein decreases expression EXP lead tetraacetate results in decreased expression of APP mRNA CTD PMID:20865013 NCBI chr16:84,952,666...85,175,255
Ensembl chr16:84,949,685...85,173,766
JBrowse link
G Mapt microtubule-associated protein tau decreases expression EXP lead tetraacetate results in decreased expression of MAPT mRNA CTD PMID:20865013 NCBI chr11:104,229,409...104,332,090
Ensembl chr11:104,231,390...104,332,090
JBrowse link
G Nrxn1 neurexin I decreases expression EXP lead tetraacetate results in decreased expression of NRXN1 mRNA CTD PMID:20865013 NCBI chr17:90,033,644...91,093,159
Ensembl chr17:90,033,631...91,093,071
JBrowse link
G Prnp prion protein decreases expression EXP lead tetraacetate results in decreased expression of PRNP mRNA CTD PMID:20865013 NCBI chr 2:131,909,928...131,938,436
Ensembl chr 2:131,909,928...131,938,429
JBrowse link
G Syp synaptophysin decreases expression EXP lead tetraacetate results in decreased expression of SYP mRNA CTD PMID:20865013 NCBI chr  X:7,638,580...7,653,256
Ensembl chr  X:7,638,471...7,653,256
JBrowse link
G Tubb3 tubulin, beta 3 class III decreases expression EXP lead tetraacetate results in decreased expression of TUBB3 mRNA CTD PMID:20865013 NCBI chr 8:123,411,553...123,422,015
Ensembl chr 8:123,411,424...123,422,015
JBrowse link
thallium(I) acetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sod1 superoxide dismutase 1, soluble decreases activity ISO thallium acetate results in decreased activity of SOD1 protein CTD PMID:15833379 NCBI chr16:90,220,762...90,226,333
Ensembl chr16:90,220,754...90,226,329
JBrowse link
zinc acetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 multiple interactions EXP [ATP7B gene mutant form results in increased susceptibility to Zinc Acetate] promotes the reaction [NR1H4 protein binds to ABCB11 promoter]; [ATP7B gene mutant form results in increased susceptibility to Zinc Acetate] promotes the reaction [RXRA protein binds to ABCB11 promoter]; [ATP7B gene mutant form results in increased susceptibility to Zinc Acetate] which results in increased expression of ABCB11 mRNA CTD PMID:26241054 NCBI chr 2:69,238,282...69,342,616
Ensembl chr 2:69,238,282...69,342,616
JBrowse link
G Agl amylo-1,6-glucosidase, 4-alpha-glucanotransferase multiple interactions
decreases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of AGL mRNA
Zinc Acetate results in decreased expression of AGL mRNA
CTD PMID:16357179 NCBI chr 3:116,739,999...116,808,166
Ensembl chr 3:116,739,999...116,808,166
JBrowse link
G Alad aminolevulinate, delta-, dehydratase increases activity
multiple interactions
ISO Zinc Acetate results in increased activity of ALAD protein
[Zinc Acetate results in increased activity of ALAD protein] which results in increased chemical synthesis of Porphobilinogen; Zinc Acetate inhibits the reaction [Dithiothreitol results in increased activity of ALAD protein]
CTD PMID:21360559 NCBI chr 4:62,505,984...62,520,063
Ensembl chr 4:62,509,169...62,519,918
JBrowse link
G Aldh5a1 aldhehyde dehydrogenase family 5, subfamily A1 multiple interactions
increases expression
ISO motexafin gadolinium inhibits the reaction [Zinc Acetate results in increased expression of ALDH5A1 mRNA] CTD PMID:16357179 NCBI chr13:24,907,579...24,937,661
Ensembl chr13:24,907,579...24,937,661
JBrowse link
G Aldh6a1 aldehyde dehydrogenase family 6, subfamily A1 multiple interactions
increases expression
ISO Zinc Acetate inhibits the reaction [motexafin gadolinium results in decreased expression of ALDH6A1 mRNA]
Zinc Acetate results in increased expression of ALDH6A1 mRNA
CTD PMID:16357179 NCBI chr12:84,430,717...84,451,024
Ensembl chr12:84,430,717...84,451,004
JBrowse link
G Arhgap17 Rho GTPase activating protein 17 multiple interactions
decreases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of ARHGAP17 mRNA
Zinc Acetate results in decreased expression of ARHGAP17 mRNA
CTD PMID:16357179 NCBI chr 7:123,279,149...123,369,948
Ensembl chr 7:123,279,218...123,369,915
JBrowse link
G Atf3 activating transcription factor 3 multiple interactions
increases expression
ISO motexafin gadolinium promotes the reaction [Zinc Acetate results in increased expression of ATF3 mRNA] CTD PMID:16357179 NCBI chr 1:191,170,296...191,183,333
Ensembl chr 1:191,170,296...191,218,039
JBrowse link
G Atm ataxia telangiectasia mutated multiple interactions
increases expression
ISO motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of ATM mRNA] CTD PMID:16357179 NCBI chr 9:53,437,122...53,536,828
Ensembl chr 9:53,439,149...53,536,740
JBrowse link
G Atp7b ATPase, Cu++ transporting, beta polypeptide increases response to substance
multiple interactions
EXP ATP7B gene mutant form results in increased susceptibility to Zinc Acetate
[ATP7B gene mutant form results in increased susceptibility to Zinc Acetate] promotes the reaction [NR1H4 protein binds to ABCB11 promoter]; [ATP7B gene mutant form results in increased susceptibility to Zinc Acetate] promotes the reaction [RXRA protein binds to ABCB11 promoter]; [ATP7B gene mutant form results in increased susceptibility to Zinc Acetate] promotes the reaction [RXRA protein binds to NR0B2 promoter]; [ATP7B gene mutant form results in increased susceptibility to Zinc Acetate] which results in increased expression of ABCB11 mRNA; [ATP7B gene mutant form results in increased susceptibility to Zinc Acetate] which results in increased expression of NR0B2 mRNA; [ATP7B gene mutant form results in increased susceptibility to Zinc Acetate] which results in increased expression of RXRA mRNA
CTD PMID:26241054 NCBI chr 8:21,992,783...22,060,074
Ensembl chr 8:21,992,785...22,060,305
JBrowse link
G Atr ataxia telangiectasia and Rad3 related multiple interactions
decreases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of ATR mRNA
Zinc Acetate results in decreased expression of ATR mRNA
CTD PMID:16357179 NCBI chr 9:95,857,597...95,953,217
Ensembl chr 9:95,857,597...95,951,781
JBrowse link
G Bach1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of BACH1 mRNA
Zinc Acetate results in increased expression of BACH1 mRNA
CTD PMID:16357179 NCBI chr16:87,698,954...87,733,346
Ensembl chr16:87,698,945...87,733,346
JBrowse link
G Bag3 BCL2-associated athanogene 3 multiple interactions
increases expression
ISO motexafin gadolinium promotes the reaction [Zinc Acetate results in increased expression of BAG3 mRNA] CTD PMID:16357179 NCBI chr 7:128,523,583...128,546,981
Ensembl chr 7:128,523,616...128,546,981
JBrowse link
G Bbc3 BCL2 binding component 3 multiple interactions ISO [Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of BBC3 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of BBC3 protein] CTD PMID:20530418 NCBI chr 7:16,308,398...16,318,334
Ensembl chr 7:16,308,393...16,318,205
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 increases expression
multiple interactions
ISO Zinc Acetate results in increased expression of BIRC5 mRNA
motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of BIRC5 mRNA]
CTD PMID:16357179 NCBI chr11:117,849,237...117,855,743
Ensembl chr11:117,849,251...117,855,743
JBrowse link
G Bmt2 base methyltransferase of 25S rRNA 2 multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of BMT2 mRNA
Zinc Acetate results in increased expression of BMT2 mRNA
CTD PMID:16357179 NCBI chr 6:13,625,675...13,677,966
Ensembl chr 6:13,625,673...13,677,966
JBrowse link
G Bnip3 BCL2/adenovirus E1B interacting protein 3 multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of BNIP3 mRNA
Zinc Acetate results in increased expression of BNIP3 mRNA
CTD PMID:16357179 NCBI chr 7:138,890,836...138,909,506
Ensembl chr 7:138,890,836...138,909,519
JBrowse link
G Bnip3l BCL2/adenovirus E1B interacting protein 3-like multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of BNIP3L mRNA
Zinc Acetate results in increased expression of BNIP3L mRNA
CTD PMID:16357179 NCBI chr14:66,985,238...67,008,877
Ensembl chr14:66,985,239...67,008,877
JBrowse link
G Canx calnexin increases expression
multiple interactions
ISO Zinc Acetate results in increased expression of CANX mRNA
[Zinc Acetate co-treated with motexafin gadolinium] affects the expression of CANX mRNA
CTD PMID:16357179 NCBI chr11:50,293,957...50,325,673
Ensembl chr11:50,293,961...50,325,673
JBrowse link
G Casp3 caspase 3 multiple interactions
decreases expression
ISO [Taurine co-treated with Zinc Acetate] inhibits the reaction [Doxorubicin results in increased expression of CASP3 protein]
Zinc Acetate results in decreased expression of CASP3 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CASP3 mRNA
CTD PMID:16357179, PMID:26335259 NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689
JBrowse link
G Cbfb core binding factor beta increases expression
multiple interactions
ISO Zinc Acetate results in increased expression of CBFB mRNA
[Zinc Acetate co-treated with motexafin gadolinium] affects the expression of CBFB mRNA
CTD PMID:16357179 NCBI chr 8:105,170,674...105,217,989
Ensembl chr 8:105,170,674...105,217,989
JBrowse link
G Ccnj cyclin J multiple interactions
decreases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CCNJ mRNA
Zinc Acetate results in decreased expression of CCNJ mRNA
CTD PMID:16357179 NCBI chr19:40,830,959...40,848,572
Ensembl chr19:40,831,279...40,848,572
JBrowse link
G Cdc16 CDC16 cell division cycle 16 multiple interactions
decreases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CDC16 mRNA
Zinc Acetate results in decreased expression of CDC16 mRNA
CTD PMID:16357179 NCBI chr 8:13,757,649...13,781,951
Ensembl chr 8:13,757,676...13,781,938
JBrowse link
G Cdc25c cell division cycle 25C multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of CDC25C mRNA
Zinc Acetate results in increased expression of CDC25C mRNA
CTD PMID:16357179 NCBI chr18:34,732,993...34,751,564
Ensembl chr18:34,732,993...34,751,533
JBrowse link
G Cdc27 cell division cycle 27 increases expression
multiple interactions
ISO Zinc Acetate results in increased expression of CDC27 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] affects the expression of CDC27 mRNA
CTD PMID:16357179 NCBI chr11:104,502,524...104,550,620
Ensembl chr11:104,502,745...104,550,620
JBrowse link
G Cdc5l cell division cycle 5-like (S. pombe) decreases expression
multiple interactions
ISO Zinc Acetate results in decreased expression of CDC5L mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CDC5L mRNA
CTD PMID:16357179 NCBI chr17:45,391,887...45,433,707
Ensembl chr17:45,391,884...45,433,737
JBrowse link
G Cdca2 cell division cycle associated 2 multiple interactions
decreases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CDCA2 mRNA
Zinc Acetate results in decreased expression of CDCA2 mRNA
CTD PMID:16357179 NCBI chr14:67,673,180...67,715,841
Ensembl chr14:67,676,331...67,715,841
JBrowse link
G Cdk19 cyclin-dependent kinase 19 increases expression ISO Zinc Acetate results in increased expression of CDK19 mRNA CTD PMID:16357179 NCBI chr10:40,349,287...40,483,818
Ensembl chr10:40,339,564...40,483,818
JBrowse link
G Cdk2 cyclin-dependent kinase 2 multiple interactions
increases expression
ISO motexafin gadolinium inhibits the reaction [Zinc Acetate results in increased expression of CDK2 mRNA] CTD PMID:16357179 NCBI chr10:128,697,938...128,705,051
Ensembl chr10:128,697,939...128,705,031
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) multiple interactions ISO [Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CDKN1A mRNA; nutlin 3 inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CDKN1A mRNA] CTD PMID:20530418 NCBI chr17:29,090,979...29,100,722
Ensembl chr17:29,090,976...29,100,727
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of CDKN1B mRNA
Zinc Acetate results in increased expression of CDKN1B mRNA
CTD PMID:16357179 NCBI chr 6:134,920,401...134,925,525
Ensembl chr 6:134,920,401...134,925,513
JBrowse link
G Cth cystathionase (cystathionine gamma-lyase) increases expression
multiple interactions
ISO Zinc Acetate results in increased expression of CTH mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of CTH mRNA
CTD PMID:16357179 NCBI chr 3:157,894,248...157,925,081
Ensembl chr 3:157,894,248...157,925,077
JBrowse link
G Cul3 cullin 3 multiple interactions
decreases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CUL3 mRNA
Zinc Acetate results in decreased expression of CUL3 mRNA
CTD PMID:16357179 NCBI chr 1:80,264,923...80,340,690
Ensembl chr 1:80,264,923...80,340,480
JBrowse link
G Cxcl1 chemokine (C-X-C motif) ligand 1 increases secretion ISO Zinc Acetate results in increased secretion of CXCL1 protein CTD PMID:21974847 NCBI chr 5:90,891,245...90,893,121
Ensembl chr 5:90,891,241...90,893,115
JBrowse link
G Cxcl15 chemokine (C-X-C motif) ligand 15 multiple interactions
increases secretion
increases expression
ISO 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Zinc Acetate results in increased expression of CXCL8 protein]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [Zinc Acetate results in increased expression of CXCL8 protein]; MYD88 mutant form inhibits the reaction [Zinc Acetate results in increased expression of CXCL8 protein]
Zinc Acetate results in increased secretion of CXCL8 protein
CTD PMID:21974847, PMID:24080332 NCBI chr 5:90,794,534...90,803,067
Ensembl chr 5:90,794,534...90,803,067
JBrowse link
G Cxcl3 chemokine (C-X-C motif) ligand 3 increases secretion ISO Zinc Acetate results in increased secretion of CXCL1 protein CTD PMID:21974847 NCBI chr 5:90,786,101...90,788,093
Ensembl chr 5:90,786,103...90,789,600
JBrowse link
G Cyb5r1 cytochrome b5 reductase 1 increases expression
multiple interactions
ISO Zinc Acetate results in increased expression of CYB5R1 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of CYB5R1 mRNA
CTD PMID:16357179 NCBI chr 1:134,405,781...134,411,738
Ensembl chr 1:134,405,559...134,411,740
JBrowse link
G Dapk3 death-associated protein kinase 3 increases expression
multiple interactions
ISO Zinc Acetate results in increased expression of DAPK3 mRNA
motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of DAPK3 mRNA]
CTD PMID:16357179 NCBI chr10:81,182,987...81,193,197
Ensembl chr10:81,183,005...81,193,197
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression
ISO motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of DDIT3 mRNA] CTD PMID:16357179 NCBI chr10:127,290,793...127,296,291
Ensembl chr10:127,290,774...127,296,288
Ensembl chr10:127,290,774...127,296,288
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 multiple interactions
increases expression
ISO motexafin gadolinium promotes the reaction [Zinc Acetate results in increased expression of DDIT4 mRNA]; Zinc Acetate promotes the reaction [motexafin gadolinium results in increased expression of DDIT4 mRNA] CTD PMID:16357179 NCBI chr10:59,949,675...59,951,770
Ensembl chr10:59,949,669...59,951,834
JBrowse link
G Dedd2 death effector domain-containing DNA binding protein 2 increases expression
multiple interactions
ISO Zinc Acetate results in increased expression of DEDD2 mRNA
motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of DEDD2 mRNA]
CTD PMID:16357179 NCBI chr 7:25,199,912...25,220,614
Ensembl chr 7:25,199,915...25,220,615
JBrowse link
G Dffb DNA fragmentation factor, beta subunit multiple interactions
decreases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of DFFB mRNA
Zinc Acetate results in decreased expression of DFFB mRNA
CTD PMID:16357179 NCBI chr 4:153,964,447...153,975,121
Ensembl chr 4:153,964,449...153,975,126
JBrowse link
G Dhcr7 7-dehydrocholesterol reductase decreases expression ISO Zinc Acetate results in decreased expression of DHCR7 mRNA CTD PMID:16357179 NCBI chr 7:143,823,167...143,848,410
Ensembl chr 7:143,823,145...143,848,410
JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 decreases expression
multiple interactions
ISO Zinc Acetate results in decreased expression of DNAJB1 mRNA
motexafin gadolinium inhibits the reaction [Zinc Acetate results in decreased expression of DNAJB1 mRNA]
CTD PMID:16357179 NCBI chr 8:83,608,175...83,612,653
Ensembl chr 8:83,608,193...83,612,653
JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of DNAJB4 mRNA
Zinc Acetate results in increased expression of DNAJB4 mRNA
CTD PMID:16357179 NCBI chr 3:152,181,580...152,210,432
Ensembl chr 3:152,178,511...152,210,302
JBrowse link
G Dnajb6 DnaJ heat shock protein family (Hsp40) member B6 multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of DNAJB6 mRNA
Zinc Acetate results in increased expression of DNAJB6 mRNA
CTD PMID:16357179 NCBI chr 5:29,735,898...29,786,478
Ensembl chr 5:29,735,688...29,818,134
JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 multiple interactions
increases expression
ISO motexafin gadolinium inhibits the reaction [Zinc Acetate results in increased expression of DNAJC3 mRNA] CTD PMID:16357179 NCBI chr14:118,937,932...118,981,702
Ensembl chr14:118,937,976...118,981,697
JBrowse link
G Drd1 dopamine receptor D1 multiple interactions ISO Zinc Acetate inhibits the reaction [SCH 23390 binds to DRD1 protein] CTD PMID:9109525 NCBI chr13:54,051,183...54,055,658
Ensembl chr13:54,051,183...54,055,705
JBrowse link
G Drd2 dopamine receptor D2 multiple interactions ISO Zinc Acetate inhibits the reaction [3-N-methylspiperone binds to DRD2 protein] CTD PMID:9109525 NCBI chr 9:49,340,360...49,408,177
Ensembl chr 9:49,340,627...49,408,177
JBrowse link
G Dusp1 dual specificity phosphatase 1 multiple interactions ISO [Taurine co-treated with Zinc Acetate] results in increased expression of DUSP1 mRNA; [Taurine co-treated with Zinc Acetate] results in increased expression of DUSP1 protein CTD PMID:26335259 NCBI chr17:26,505,591...26,508,472
Ensembl chr17:26,505,590...26,562,128
JBrowse link
G E2f1 E2F transcription factor 1 increases expression
multiple interactions
ISO Zinc Acetate results in increased expression of E2F1 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of E2F1 mRNA
CTD PMID:16357179 NCBI chr 2:154,559,400...154,569,892
Ensembl chr 2:154,559,407...154,569,892
JBrowse link
G E2f3 E2F transcription factor 3 multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of E2F3 mRNA
Zinc Acetate results in increased expression of E2F3 mRNA
CTD PMID:16357179 NCBI chr13:29,906,575...29,986,064
Ensembl chr13:29,906,575...29,986,063
JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 increases expression
multiple interactions
ISO Zinc Acetate results in increased expression of EGLN1 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of EGLN1 mRNA
CTD PMID:16357179 NCBI chr 8:124,908,587...124,949,254
Ensembl chr 8:124,908,587...124,949,324
JBrowse link
G Elp1 elongator complex protein 1 multiple interactions
decreases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of ELP1 mRNA
Zinc Acetate results in decreased expression of ELP1 mRNA
CTD PMID:16357179 NCBI chr 4:56,746,547...56,802,569
Ensembl chr 4:56,749,680...56,802,331
JBrowse link
G Eno1 enolase 1, alpha non-neuron increases expression ISO Zinc Acetate results in increased expression of ENO1 mRNA CTD PMID:16357179 NCBI chr 4:150,236,708...150,248,879
Ensembl chr 4:150,236,721...150,248,879
JBrowse link
G Fadd Fas (TNFRSF6)-associated via death domain multiple interactions
decreases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of FADD mRNA
Zinc Acetate results in decreased expression of FADD mRNA
CTD PMID:16357179 NCBI chr 7:144,578,323...144,582,441
Ensembl chr 7:144,577,318...144,582,463
JBrowse link
G Faim Fas apoptotic inhibitory molecule multiple interactions
decreases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of FAIM mRNA
Zinc Acetate results in decreased expression of FAIM mRNA
CTD PMID:16357179 NCBI chr 9:98,986,373...99,002,019
Ensembl chr 9:98,986,373...99,002,021
JBrowse link
G Fam162a family with sequence similarity 162, member A multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of FAM162A mRNA
Zinc Acetate results in increased expression of FAM162A mRNA
CTD PMID:16357179 NCBI chr16:36,043,844...36,071,561
Ensembl chr16:36,043,761...36,071,594
JBrowse link
G Fasn fatty acid synthase decreases expression ISO Zinc Acetate results in decreased expression of FASN mRNA CTD PMID:16357179 NCBI chr11:120,805,958...120,825,166
Ensembl chr11:120,805,846...120,824,547
JBrowse link
G Foxo3 forkhead box O3 multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of FOXO3 mRNA
Zinc Acetate results in increased expression of FOXO3 mRNA
CTD PMID:16357179 NCBI chr10:42,181,845...42,276,695
Ensembl chr10:42,181,841...42,276,755
JBrowse link
G Gclm glutamate-cysteine ligase, modifier subunit increases expression
multiple interactions
ISO Zinc Acetate results in increased expression of GCLM mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of GCLM mRNA
CTD PMID:16357179 NCBI chr 3:122,245,487...122,267,215
Ensembl chr 3:122,245,557...122,270,732
JBrowse link
G Gls glutaminase multiple interactions
decreases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of GLS mRNA
Zinc Acetate results in decreased expression of GLS mRNA
CTD PMID:16357179 NCBI chr 1:52,163,449...52,235,009
Ensembl chr 1:52,163,448...52,233,232
JBrowse link
G Gpr146 G protein-coupled receptor 146 increases expression ISO Zinc Acetate results in increased expression of GPR146 mRNA CTD PMID:16357179 NCBI chr 5:139,377,697...139,396,415
Ensembl chr 5:139,377,697...139,396,415
JBrowse link
G Gpt2 glutamic pyruvate transaminase (alanine aminotransferase) 2 increases expression ISO Zinc Acetate results in increased expression of GPT2 mRNA CTD PMID:16357179 NCBI chr 8:85,492,576...85,528,902
Ensembl chr 8:85,492,576...85,527,560
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions ISO [Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of GPX1 mRNA; nutlin 3 inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of GPX1 mRNA] CTD PMID:20530418 NCBI chr 9:108,339,080...108,340,342
Ensembl chr 9:108,338,903...108,340,343
JBrowse link
G Gsr glutathione reductase multiple interactions
decreases activity
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of GSR mRNA
Zinc Acetate results in decreased activity of GSR protein
Zinc Acetate results in increased expression of GSR mRNA
CTD PMID:16357179, PMID:17382203 NCBI chr 8:33,653,238...33,698,162
Ensembl chr 8:33,652,523...33,698,163
JBrowse link
G Gtf3c2 general transcription factor IIIC, polypeptide 2, beta increases expression ISO Zinc Acetate results in increased expression of GTF3C2 mRNA CTD PMID:16357179 NCBI chr 5:31,156,006...31,180,144
Ensembl chr 5:31,156,005...31,180,144
JBrowse link
G Hbp1 high mobility group box transcription factor 1 increases expression
multiple interactions
ISO Zinc Acetate results in increased expression of HBP1 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of HBP1 mRNA
CTD PMID:16357179 NCBI chr12:31,926,452...31,950,530
Ensembl chr12:31,926,254...31,950,535
JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit multiple interactions
increases expression
ISO [motexafin gadolinium co-treated with Zinc Acetate] results in increased expression of HIF1A protein
Zinc Acetate results in increased expression of HIF1A protein
CTD PMID:16357179 NCBI chr12:73,901,324...73,947,554
Ensembl chr12:73,901,375...73,947,530
JBrowse link
G Hilpda hypoxia inducible lipid droplet associated multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of HILPDA mRNA
Zinc Acetate results in increased expression of HILPDA mRNA
CTD PMID:16357179 NCBI chr 6:29,272,488...29,275,449
Ensembl chr 6:29,272,488...29,275,446
JBrowse link
G Hipk1 homeodomain interacting protein kinase 1 multiple interactions
increases expression
ISO motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of HIPK1 mRNA] CTD PMID:16357179 NCBI chr 3:103,739,815...103,791,894
Ensembl chr 3:103,739,815...103,791,563
JBrowse link
G Hltf helicase-like transcription factor multiple interactions
decreases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of HLTF mRNA
Zinc Acetate results in decreased expression of HLTF mRNA
CTD PMID:16357179 NCBI chr 3:20,057,808...20,118,491
Ensembl chr 3:20,057,811...20,118,490
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO [motexafin gadolinium co-treated with Zinc Acetate] results in increased expression of HMOX1 protein; motexafin gadolinium promotes the reaction [Zinc Acetate results in increased expression of HMOX1 mRNA]
[Taurine co-treated with Zinc Acetate] results in increased expression of HMOX1 protein
CTD PMID:16357179, PMID:26335259 NCBI chr 8:75,093,618...75,100,593
Ensembl chr 8:75,093,621...75,100,589
JBrowse link
G Hrk harakiri, BCL2 interacting protein (contains only BH3 domain) increases expression
multiple interactions
ISO Zinc Acetate results in increased expression of HRK mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of HRK mRNA
CTD PMID:16357179 NCBI chr 5:118,169,764...118,189,478
Ensembl chr 5:118,164,648...118,189,478
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of HSP90AB1 mRNA
Zinc Acetate results in increased expression of HSP90AB1 mRNA
CTD PMID:16357179 NCBI chr17:45,567,778...45,573,261
Ensembl chr17:45,567,775...45,573,271
JBrowse link
G Hspa1a heat shock protein 1A multiple interactions
increases expression
ISO motexafin gadolinium promotes the reaction [Zinc Acetate results in increased expression of HSPA1A mRNA]; Zinc Acetate promotes the reaction [motexafin gadolinium results in increased expression of HSPA1A mRNA] CTD PMID:16357179 NCBI chr17:34,969,359...34,972,156
Ensembl chr17:34,969,190...34,972,156
JBrowse link
G Hspa1b heat shock protein 1B multiple interactions
increases expression
ISO motexafin gadolinium promotes the reaction [Zinc Acetate results in increased expression of HSPA1B mRNA]; Zinc Acetate promotes the reaction [motexafin gadolinium results in increased expression of HSPA1B mRNA] CTD PMID:16357179 NCBI chr17:34,956,429...34,959,238
Ensembl chr17:34,956,436...34,959,238
JBrowse link
G Hspa4 heat shock protein 4 multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of HSPA4 mRNA
Zinc Acetate results in increased expression of HSPA4 mRNA
CTD PMID:16357179 NCBI chr11:53,259,814...53,300,479
Ensembl chr11:53,259,814...53,300,457
JBrowse link
G Hspa4l heat shock protein 4 like multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of HSPA4L mRNA
Zinc Acetate results in increased expression of HSPA4L mRNA
CTD PMID:16357179 NCBI chr 3:40,744,500...40,796,103
Ensembl chr 3:40,745,382...40,796,103
Ensembl chr 3:40,745,382...40,796,103
JBrowse link
G Hspb1 heat shock protein 1 multiple interactions
increases expression
ISO motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of HSPB1 mRNA] CTD PMID:16357179 NCBI chr 5:135,887,919...135,889,563
Ensembl chr 5:135,887,919...135,889,563
JBrowse link
G Hspd1 heat shock protein 1 (chaperonin) multiple interactions
increases expression
ISO motexafin gadolinium promotes the reaction [Zinc Acetate results in increased expression of HSPD1 mRNA] CTD PMID:16357179 NCBI chr 1:55,077,833...55,088,243
Ensembl chr 1:55,077,835...55,088,243
JBrowse link
G Hsph1 heat shock 105kDa/110kDa protein 1 multiple interactions
increases expression
ISO motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of HSPH1 mRNA] CTD PMID:16357179 NCBI chr 5:149,616,843...149,636,498
Ensembl chr 5:149,614,287...149,636,376
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions
increases expression
ISO 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Zinc Acetate results in increased expression of ICAM1 protein]; [Zinc Acetate results in increased phosphorylation of NFKBIA protein] inhibits the reaction [Zinc Acetate results in increased expression of ICAM1 protein]; MYD88 mutant form inhibits the reaction [Zinc Acetate results in increased expression of ICAM1 protein] CTD PMID:24080332 NCBI chr 9:21,015,940...21,028,814
Ensembl chr 9:21,015,985...21,028,817
JBrowse link
G Id2 inhibitor of DNA binding 2 multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of ID2 mRNA
Zinc Acetate results in increased expression of ID2 mRNA
CTD PMID:16357179 NCBI chr12:25,093,799...25,096,092
Ensembl chr12:25,093,799...25,097,140
JBrowse link
G Ikbke inhibitor of kappaB kinase epsilon multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of IKBKE mRNA
Zinc Acetate results in increased expression of IKBKE mRNA
CTD PMID:16357179 NCBI chr 1:131,254,600...131,279,601
Ensembl chr 1:131,254,343...131,279,606
JBrowse link
G Il10 interleukin 10 increases secretion ISO Zinc Acetate results in increased secretion of IL10 protein CTD PMID:21974847 NCBI chr 1:131,019,845...131,024,970
Ensembl chr 1:131,019,845...131,024,974
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [Taurine co-treated with Zinc Acetate] results in decreased expression of IL1B protein CTD PMID:27501764 NCBI chr 2:129,364,569...129,371,164
Ensembl chr 2:129,364,570...129,371,139
JBrowse link
G Il6 interleukin 6 increases secretion ISO Zinc Acetate results in increased secretion of IL6 protein CTD PMID:21974847 NCBI chr 5:30,013,114...30,019,975
Ensembl chr 5:30,013,114...30,019,981
JBrowse link
G Il7 interleukin 7 increases secretion ISO Zinc Acetate results in increased secretion of IL7 protein CTD PMID:21974847 NCBI chr 3:7,572,028...7,613,760
Ensembl chr 3:7,569,994...7,613,760
JBrowse link
G Irf2bp2 interferon regulatory factor 2 binding protein 2 multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of IRF2BP2 mRNA
Zinc Acetate results in increased expression of IRF2BP2 mRNA
CTD PMID:16357179 NCBI chr 8:126,588,296...126,593,986
Ensembl chr 8:126,588,296...126,593,986
JBrowse link
G Jund jun D proto-oncogene multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of JUND mRNA
Zinc Acetate results in increased expression of JUND mRNA
CTD PMID:16357179 NCBI chr 8:70,697,739...70,700,616
Ensembl chr 8:70,698,949...70,700,616
JBrowse link
G Kdm3a lysine (K)-specific demethylase 3A increases expression ISO Zinc Acetate results in increased expression of KDM3A mRNA CTD PMID:16357179 NCBI chr 6:71,588,970...71,632,990
Ensembl chr 6:71,588,972...71,632,990
JBrowse link
G Klra17 killer cell lectin-like receptor, subfamily A, member 17 increases expression ISO Zinc Acetate results in increased expression of ZNF302 mRNA CTD PMID:16357179 NCBI chr 6:129,831,154...129,876,672
Ensembl chr 6:129,831,154...129,876,672
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO [Taurine co-treated with Zinc Acetate] results in decreased expression of MAPK8 protein modified form CTD PMID:27501764 NCBI chr14:33,377,898...33,447,353
Ensembl chr14:33,377,898...33,447,158
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions ISO [Taurine co-treated with Zinc Acetate] results in decreased expression of MAPK9 protein modified form CTD PMID:27501764 NCBI chr11:49,846,728...49,886,421
Ensembl chr11:49,846,751...49,886,421
JBrowse link
G Mapt microtubule-associated protein tau multiple interactions ISO [Zinc Acetate results in decreased abundance of Copper] which results in decreased phosphorylation of MAPT protein CTD PMID:25671100 NCBI chr11:104,229,409...104,332,090
Ensembl chr11:104,231,390...104,332,090
JBrowse link
G Mdm2 transformed mouse 3T3 cell double minute 2 multiple interactions
increases expression
ISO motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of MDM2 mRNA] CTD PMID:16357179 NCBI chr10:117,688,875...117,710,758
Ensembl chr10:117,688,875...117,710,758
JBrowse link
G Mob1a MOB kinase activator 1A increases expression
multiple interactions
ISO Zinc Acetate results in increased expression of MOB1A mRNA
motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of MOB1A mRNA]
CTD PMID:16357179 NCBI chr 6:83,326,034...83,342,812
Ensembl chr 6:83,326,016...83,343,776
JBrowse link
G Mt1 metallothionein 1 increases expression
multiple interactions
EXP
ISO
Zinc Acetate results in increased expression of MT1 protein
motexafin gadolinium promotes the reaction [Zinc Acetate results in increased expression of MT1X mRNA]; Zinc Acetate promotes the reaction [motexafin gadolinium results in increased expression of MT1X mRNA]
CTD PMID:15306638, PMID:16357179 NCBI chr 8:94,178,883...94,180,327
Ensembl chr 8:94,179,082...94,180,327
JBrowse link
G Mt2 metallothionein 2 increases expression
multiple interactions
EXP
ISO
Zinc Acetate results in increased expression of MT2 mRNA; Zinc Acetate results in increased expression of MT2 protein
Zinc Acetate results in increased expression of MT2A mRNA
motexafin gadolinium promotes the reaction [Zinc Acetate results in increased expression of MT2A mRNA]
CTD PMID:8876661, PMID:15306638, PMID:16357179 NCBI chr 8:94,172,618...94,173,567
Ensembl chr 8:94,172,664...94,173,568
JBrowse link
G Myd88 myeloid differentiation primary response gene 88 multiple interactions
decreases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of MYD88 mRNA; MYD88 mutant form inhibits the reaction [Zinc Acetate results in increased expression of CXCL8 protein]; MYD88 mutant form inhibits the reaction [Zinc Acetate results in increased expression of ICAM1 protein]
Zinc Acetate results in decreased expression of MYD88 mRNA
CTD PMID:16357179, PMID:24080332 NCBI chr 9:119,335,934...119,340,018
Ensembl chr 9:119,335,934...119,341,411
JBrowse link
G Nadk NAD kinase multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of NADK mRNA
Zinc Acetate results in increased expression of NADK mRNA
CTD PMID:16357179 NCBI chr 4:155,562,381...155,591,001
Ensembl chr 4:155,562,378...155,591,001
JBrowse link
G Nf1 neurofibromin 1 increases expression
multiple interactions
ISO Zinc Acetate results in increased expression of NF1 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of NF1 mRNA
CTD PMID:16357179 NCBI chr11:79,339,590...79,581,609
Ensembl chr11:79,339,693...79,581,612
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha increases degradation
multiple interactions
increases phosphorylation
ISO Zinc Acetate results in increased degradation of NFKBIA protein
[Zinc Acetate results in increased phosphorylation of NFKBIA protein] inhibits the reaction [Zinc Acetate results in increased expression of ICAM1 protein]
CTD PMID:21974847, PMID:24080332 NCBI chr12:55,489,409...55,492,647
Ensembl chr12:55,489,410...55,492,647
JBrowse link
G Nisch nischarin decreases expression ISO Zinc Acetate results in decreased expression of NISCH mRNA CTD PMID:16357179 NCBI chr14:31,170,928...31,206,826
Ensembl chr14:31,170,930...31,216,946
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 multiple interactions EXP [ATP7B gene mutant form results in increased susceptibility to Zinc Acetate] promotes the reaction [RXRA protein binds to NR0B2 promoter]; [ATP7B gene mutant form results in increased susceptibility to Zinc Acetate] which results in increased expression of NR0B2 mRNA CTD PMID:26241054 NCBI chr 4:133,553,376...133,556,686
Ensembl chr 4:133,553,376...133,556,536
JBrowse link
G Nr1d2 nuclear receptor subfamily 1, group D, member 2 multiple interactions
increases expression
ISO motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of NR1D2 mRNA] CTD PMID:16357179 NCBI chr14:18,204,056...18,239,106
Ensembl chr14:18,204,054...18,239,127
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions EXP [ATP7B gene mutant form results in increased susceptibility to Zinc Acetate] promotes the reaction [NR1H4 protein binds to ABCB11 promoter] CTD PMID:26241054 NCBI chr10:89,454,234...89,533,645
Ensembl chr10:89,454,234...89,533,585
JBrowse link
G P4hb prolyl 4-hydroxylase, beta polypeptide multiple interactions
increases expression
ISO motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of P4HB mRNA] CTD PMID:16357179 NCBI chr11:120,560,298...120,573,253
Ensembl chr11:120,560,298...120,573,253
JBrowse link
G Pdcd11 programmed cell death 11 decreases expression ISO Zinc Acetate results in decreased expression of PDCD11 mRNA CTD PMID:16357179 NCBI chr19:47,090,735...47,131,146
Ensembl chr19:47,090,768...47,131,865
JBrowse link
G Pdcd4 programmed cell death 4 multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of PDCD4 mRNA
Zinc Acetate results in increased expression of PDCD4 mRNA
CTD PMID:16357179 NCBI chr19:53,892,231...53,937,592
Ensembl chr19:53,892,231...53,929,860
JBrowse link
G Pdcd5 programmed cell death 5 multiple interactions
decreases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of PDCD5 mRNA
Zinc Acetate results in decreased expression of PDCD5 mRNA
CTD PMID:16357179 NCBI chr 7:35,641,985...35,647,482
Ensembl chr 7:35,641,982...35,647,521
JBrowse link
G Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of PFKFB3 mRNA
Zinc Acetate results in increased expression of PFKFB3 mRNA
CTD PMID:16357179 NCBI chr 2:11,471,430...11,554,071
Ensembl chr 2:11,471,433...11,554,077
JBrowse link
G Pfkfb4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of PFKFB4 mRNA
Zinc Acetate results in increased expression of PFKFB4 mRNA
CTD PMID:16357179 NCBI chr 9:108,988,272...109,032,236
Ensembl chr 9:108,991,778...109,032,228
JBrowse link
G Pgk1 phosphoglycerate kinase 1 increases expression
multiple interactions
ISO Zinc Acetate results in increased expression of PGK1 mRNA
motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of PGK1 mRNA]
CTD PMID:16357179 NCBI chr  X:106,187,100...106,203,699
Ensembl chr  X:106,187,100...106,203,699
JBrowse link
G Phtf2 putative homeodomain transcription factor 2 multiple interactions
increases expression
ISO motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of PHTF2 mRNA] CTD PMID:16357179 NCBI chr 5:20,758,664...20,882,137
Ensembl chr 5:20,758,663...20,882,124
JBrowse link
G Pias1 protein inhibitor of activated STAT 1 multiple interactions
increases expression
ISO motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of PIAS1 mRNA] CTD PMID:16357179 NCBI chr 9:62,878,366...62,980,879
Ensembl chr 9:62,878,368...62,987,924
JBrowse link
G Pik3ip1 phosphoinositide-3-kinase interacting protein 1 multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of PIK3IP1 mRNA
Zinc Acetate results in increased expression of PIK3IP1 mRNA
CTD PMID:16357179 NCBI chr11:3,319,241...3,342,971
Ensembl chr11:3,330,401...3,342,971
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression
multiple interactions
ISO Zinc Acetate results in increased expression of PMAIP1 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of PMAIP1 mRNA
CTD PMID:16357179 NCBI chr18:66,458,604...66,465,558
Ensembl chr18:66,458,533...66,465,565
JBrowse link
G Prkacb protein kinase, cAMP dependent, catalytic, beta multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of PRKACB mRNA
Zinc Acetate results in increased expression of PRKACB mRNA
CTD PMID:16357179 NCBI chr 3:146,729,579...146,812,946
Ensembl chr 3:146,729,574...146,812,990
JBrowse link
G Prkcd protein kinase C, delta decreases expression ISO Zinc Acetate results in decreased expression of PRKCD mRNA CTD PMID:16357179 NCBI chr14:30,595,353...30,626,414
Ensembl chr14:30,595,354...30,626,210
JBrowse link
G Prkd2 protein kinase D2 decreases expression ISO Zinc Acetate results in decreased expression of PRKD2 mRNA CTD PMID:16357179 NCBI chr 7:16,842,902...16,870,461
Ensembl chr 7:16,842,902...16,870,464
JBrowse link
G Prkdc protein kinase, DNA activated, catalytic polypeptide increases expression ISO Zinc Acetate results in increased expression of PRKDC mRNA CTD PMID:16357179 NCBI chr16:15,637,444...15,842,239
Ensembl chr16:15,637,866...15,842,235
JBrowse link
G Ptrh2 peptidyl-tRNA hydrolase 2 multiple interactions
decreases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of PTRH2 mRNA
Zinc Acetate results in decreased expression of PTRH2 mRNA
CTD PMID:16357179 NCBI chr11:86,684,074...86,692,457
Ensembl chr11:86,683,985...86,692,457
JBrowse link
G Rb1 RB transcriptional corepressor 1 multiple interactions
decreases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of RB1 mRNA
Zinc Acetate results in decreased expression of RB1 mRNA
CTD PMID:16357179 NCBI chr14:73,192,858...73,325,951
Ensembl chr14:73,183,673...73,325,822
JBrowse link
G Rcbtb2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 multiple interactions
decreases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of RCBTB2 mRNA
Zinc Acetate results in decreased expression of RCBTB2 mRNA
CTD PMID:16357179 NCBI chr14:73,138,745...73,184,055
Ensembl chr14:73,123,037...73,207,843
JBrowse link
G Relb avian reticuloendotheliosis viral (v-rel) oncogene related B multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of RELB mRNA
Zinc Acetate results in increased expression of RELB mRNA
CTD PMID:16357179 NCBI chr 7:19,606,217...19,629,438
Ensembl chr 7:19,606,217...19,629,438
JBrowse link
G Rxra retinoid X receptor alpha multiple interactions EXP [ATP7B gene mutant form results in increased susceptibility to Zinc Acetate] promotes the reaction [RXRA protein binds to ABCB11 promoter]; [ATP7B gene mutant form results in increased susceptibility to Zinc Acetate] promotes the reaction [RXRA protein binds to NR0B2 promoter]; [ATP7B gene mutant form results in increased susceptibility to Zinc Acetate] which results in increased expression of RXRA mRNA CTD PMID:26241054 NCBI chr 2:27,676,445...27,763,319
Ensembl chr 2:27,676,440...27,762,957
JBrowse link
G Selenow selenoprotein W multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of SELENOW mRNA
Zinc Acetate results in increased expression of SELENOW mRNA
CTD PMID:16357179 NCBI chr 7:15,917,208...15,922,371
Ensembl chr 7:15,917,208...15,922,402
JBrowse link
G Sesn2 sestrin 2 multiple interactions
increases expression
ISO [Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of SESN2 mRNA; [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of SESN2 mRNA; nutlin 3 inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of SESN2 mRNA]
Zinc Acetate results in increased expression of SESN2 mRNA
CTD PMID:16357179, PMID:20530418 NCBI chr 4:132,492,804...132,510,456
Ensembl chr 4:132,492,032...132,510,501
JBrowse link
G Slc16a1 solute carrier family 16 (monocarboxylic acid transporters), member 1 multiple interactions
increases expression
ISO motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of SLC16A1 mRNA] CTD PMID:16357179 NCBI chr 3:104,638,664...104,658,462
Ensembl chr 3:104,638,668...104,658,462
JBrowse link
G Slc16a6 solute carrier family 16 (monocarboxylic acid transporters), member 6 increases expression
multiple interactions
ISO Zinc Acetate results in increased expression of SLC16A6 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of SLC16A6 mRNA
CTD PMID:16357179 NCBI chr11:109,450,855...109,473,598
Ensembl chr11:109,450,855...109,473,598
JBrowse link
G Slc1a4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 increases expression
multiple interactions
ISO Zinc Acetate results in increased expression of SLC1A4 mRNA
motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of SLC1A4 mRNA]
CTD PMID:16357179 NCBI chr11:20,302,180...20,332,713
Ensembl chr11:20,302,180...20,332,713
JBrowse link
G Slc30a1 solute carrier family 30 (zinc transporter), member 1 multiple interactions
increases expression
ISO motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of SLC30A1 mRNA]; Zinc Acetate affects the reaction [motexafin gadolinium results in increased expression of SLC30A1 mRNA] CTD PMID:16357179 NCBI chr 1:191,906,697...191,913,248
Ensembl chr 1:191,906,767...191,913,247
JBrowse link
G Slc31a1 solute carrier family 31, member 1 increases expression ISO Zinc Acetate results in increased expression of SLC31A1 mRNA CTD PMID:24132751 NCBI chr 4:62,360,583...62,391,769
Ensembl chr 4:62,360,727...62,391,769
JBrowse link
G Slc38a2 solute carrier family 38, member 2 multiple interactions
increases expression
ISO motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of SLC38A2 mRNA]; Zinc Acetate affects the reaction [motexafin gadolinium results in increased expression of SLC38A2 mRNA] CTD PMID:16357179 NCBI chr15:96,687,392...96,699,728
Ensembl chr15:96,687,392...96,699,730
JBrowse link
G Slc39a10 solute carrier family 39 (zinc transporter), member 10 affects expression
multiple interactions
ISO Zinc Acetate affects the expression of SLC39A10 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] affects the expression of SLC39A10 mRNA
CTD PMID:16357179 NCBI chr 1:46,807,544...46,925,776
Ensembl chr 1:46,807,544...46,892,852
JBrowse link
G Slc39a14 solute carrier family 39 (zinc transporter), member 14 multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] affects the expression of SLC39A14 mRNA
Zinc Acetate results in increased expression of SLC39A14 mRNA
CTD PMID:16357179 NCBI chr14:70,303,467...70,351,452
Ensembl chr14:70,303,469...70,351,425
JBrowse link
G Slc39a9 solute carrier family 39 (zinc transporter), member 9 multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of SLC39A9 mRNA
Zinc Acetate results in increased expression of SLC39A9 mRNA
CTD PMID:16357179 NCBI chr12:80,643,883...80,683,342
Ensembl chr12:80,643,883...80,683,342
JBrowse link
G Slc3a2 solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] affects the expression of SLC3A2 mRNA
Zinc Acetate results in increased expression of SLC3A2 mRNA
CTD PMID:16357179 NCBI chr19:8,706,882...8,723,369
Ensembl chr19:8,706,882...8,723,369
JBrowse link
G Slc43a1 solute carrier family 43, member 1 multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of SLC43A1 mRNA
Zinc Acetate results in increased expression of SLC43A1 mRNA
CTD PMID:16357179 NCBI chr 2:84,838,855...84,863,586
Ensembl chr 2:84,838,850...84,863,594
JBrowse link
G Slc7a1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] affects the expression of SLC7A1 mRNA
Zinc Acetate results in increased expression of SLC7A1 mRNA
CTD PMID:16357179 NCBI chr 5:148,327,410...148,399,904
Ensembl chr 5:148,327,410...148,399,904
JBrowse link
G Slc7a11 solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] affects the expression of SLC7A11 mRNA
Zinc Acetate results in increased expression of SLC7A11 mRNA
CTD PMID:16357179 NCBI chr 3:50,364,936...50,499,087
Ensembl chr 3:49,892,526...50,443,614
JBrowse link
G Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 multiple interactions
decreases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of SMARCA4 mRNA
Zinc Acetate results in decreased expression of SMARCA4 mRNA
CTD PMID:16357179 NCBI chr 9:21,616,106...21,704,230
Ensembl chr 9:21,616,169...21,704,230
JBrowse link
G Smarca5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 multiple interactions
decreases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of SMARCA5 mRNA
Zinc Acetate results in decreased expression of SMARCA5 mRNA
CTD PMID:16357179 NCBI chr 8:80,699,943...80,739,459
Ensembl chr 8:80,698,507...80,739,497
JBrowse link
G Sp1 trans-acting transcription factor 1 increases expression ISO Zinc Acetate results in increased expression of SP1 mRNA CTD PMID:24132751 NCBI chr15:102,406,316...102,436,404
Ensembl chr15:102,406,143...102,436,404
JBrowse link
G Tagap T cell activation Rho GTPase activating protein multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of TAGAP mRNA
Zinc Acetate results in increased expression of TAGAP mRNA
CTD PMID:16357179 NCBI chr17:7,926,000...7,934,897
Ensembl chr17:7,926,000...7,934,897
JBrowse link
G Tfrc transferrin receptor multiple interactions
increases expression
ISO motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of TFRC mRNA] CTD PMID:16357179 NCBI chr16:32,608,896...32,632,794
Ensembl chr16:32,608,920...32,632,794
JBrowse link
G Tnfaip8 tumor necrosis factor, alpha-induced protein 8 decreases expression
multiple interactions
ISO Zinc Acetate results in decreased expression of TNFAIP8 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TNFAIP8 mRNA
CTD PMID:16357179 NCBI chr18:49,979,427...50,093,229
Ensembl chr18:49,979,427...50,107,173
JBrowse link
G Tnfrsf17 tumor necrosis factor receptor superfamily, member 17 multiple interactions
decreases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TNFRSF17 mRNA
Zinc Acetate results in decreased expression of TNFRSF17 mRNA
CTD PMID:16357179 NCBI chr16:11,313,232...11,320,074
Ensembl chr16:11,313,812...11,320,074
JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a increases expression
multiple interactions
ISO Zinc Acetate results in increased expression of TNFRSF1A mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of TNFRSF1A mRNA
CTD PMID:16357179 NCBI chr 6:125,349,723...125,362,483
Ensembl chr 6:125,349,362...125,362,484
JBrowse link
G Tnfsf8 tumor necrosis factor (ligand) superfamily, member 8 multiple interactions
increases expression
ISO motexafin gadolinium inhibits the reaction [Zinc Acetate results in increased expression of TNFSF8 mRNA] CTD PMID:16357179 NCBI chr 4:63,831,202...63,861,508
Ensembl chr 4:63,831,308...63,861,347
JBrowse link
G Tnip2 TNFAIP3 interacting protein 2 decreases expression ISO Zinc Acetate results in decreased expression of TNIP2 mRNA CTD PMID:16357179 NCBI chr 5:34,496,096...34,513,979
Ensembl chr 5:34,496,087...34,513,991
JBrowse link
G Trib3 tribbles pseudokinase 3 multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of TRIB3 mRNA
Zinc Acetate results in increased expression of TRIB3 mRNA
CTD PMID:16357179 NCBI chr 2:152,337,425...152,344,060
Ensembl chr 2:152,337,422...152,344,032
JBrowse link
G Trp53 transformation related protein 53 multiple interactions ISO [Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TP53 protein; Acetylcysteine inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TP53 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TP53 protein]; nutlin 3 inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TP53 protein] CTD PMID:20530418 NCBI chr11:69,580,348...69,591,873
Ensembl chr11:69,580,359...69,591,873
JBrowse link
G Txnrd1 thioredoxin reductase 1 multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of TXNRD1 mRNA
Zinc Acetate results in increased expression of TXNRD1 mRNA
CTD PMID:16357179 NCBI chr10:82,833,951...82,897,724
Ensembl chr10:82,833,951...82,897,712
JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 multiple interactions ISO [Taurine co-treated with Zinc Acetate] results in increased expression of UGT2B1 mRNA CTD PMID:26335259 NCBI chr 5:86,916,639...86,926,503
Ensembl chr 5:86,916,638...86,926,530
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] affects the expression of VEGFA mRNA
Zinc Acetate results in increased expression of VEGFA mRNA
CTD PMID:16357179 NCBI chr17:46,016,993...46,032,377
Ensembl chr17:46,016,993...46,032,369
JBrowse link
G Vhl von Hippel-Lindau tumor suppressor increases expression
multiple interactions
ISO Zinc Acetate results in increased expression of VHL mRNA
motexafin gadolinium inhibits the reaction [Zinc Acetate results in increased expression of VHL mRNA]
CTD PMID:16357179 NCBI chr 6:113,623,994...113,631,634
Ensembl chr 6:113,623,959...113,631,633
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 21475
    chemical entity 21474
      molecular entity 21457
        ion 16556
          cation 16379
            salt 15119
              organic salt 2431
                acetate salt 176
                  (2S)-2-Ethylhexyl acetate 0
                  1-dodecylguanidine acetate 0
                  L-arginyl-L-glutamic acid monoacetate 0
                  ammonium acetate 13
                  caspofungin acetate 0
                  ceftaroline fosamil acetate + 0
                  cetrorelix acetate 0
                  cobalt(II) acetate 1
                  desmopressin acetate (anhydrous) + 0
                  flecainide acetate 0
                  histrelin acetate 0
                  icatibant acetate 0
                  lead tetraacetate 6
                  leuprolide acetate 0
                  lithium acetate 0
                  peginesatide acetate 0
                  praseodymium acetate 0
                  saxitoxin acetate 0
                  thallium(I) acetate 1
                  tris acetate 0
                  zinc acetate 158
Path 2
Term Annotations click to browse term
  CHEBI ontology 21475
    subatomic particle 21460
      composite particle 21460
        hadron 21460
          baryon 21460
            nucleon 21460
              atomic nucleus 21460
                atom 21460
                  group 21329
                    polyatomic entity 21329
                      heteroatomic molecular entity 21249
                        salt 15119
                          organic salt 2431
                            acetate salt 176
                              (2S)-2-Ethylhexyl acetate 0
                              1-dodecylguanidine acetate 0
                              L-arginyl-L-glutamic acid monoacetate 0
                              ammonium acetate 13
                              caspofungin acetate 0
                              ceftaroline fosamil acetate + 0
                              cetrorelix acetate 0
                              cobalt(II) acetate 1
                              desmopressin acetate (anhydrous) + 0
                              flecainide acetate 0
                              histrelin acetate 0
                              icatibant acetate 0
                              lead tetraacetate 6
                              leuprolide acetate 0
                              lithium acetate 0
                              peginesatide acetate 0
                              praseodymium acetate 0
                              saxitoxin acetate 0
                              thallium(I) acetate 1
                              tris acetate 0
                              zinc acetate 158
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.