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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:acetate salt
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Accession:CHEBI:59230 term browser browse the term
Definition:Any salt prepared using acetic acid as the acid component.
Synonyms:related_synonym: acetate salts


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ammonium acetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase increases activity EXP ammonium acetate results in increased activity of ADA protein CTD PMID:19900420 NCBI chr 3:160,115,840...160,139,947
Ensembl chr 3:160,115,842...160,139,947
JBrowse link
G Ampd2 adenosine monophosphate deaminase 2 increases activity EXP ammonium acetate results in increased activity of AMPD2 protein CTD PMID:19900420 NCBI chr 2:210,861,624...210,874,348
Ensembl chr 2:210,861,625...210,874,304
JBrowse link
G Ampd3 adenosine monophosphate deaminase 3 increases activity EXP ammonium acetate results in increased activity of AMPD3 protein CTD PMID:19900420 NCBI chr 1:175,585,301...175,630,479
Ensembl chr 1:175,586,097...175,630,467
JBrowse link
G Asl argininosuccinate lyase increases activity EXP ammonium acetate results in increased activity of ASL protein CTD PMID:16009439 NCBI chr12:30,160,922...30,178,348
Ensembl chr12:30,165,694...30,178,341
JBrowse link
G Ass1 argininosuccinate synthase 1 increases activity EXP ammonium acetate results in increased activity of ASS1 protein CTD PMID:16009439 NCBI chr 3:10,327,411...10,375,847
Ensembl chr 3:10,327,414...10,375,826
JBrowse link
G Cat catalase increases activity
decreases activity
multiple interactions
EXP ammonium acetate results in increased activity of CAT protein
ammonium acetate results in decreased activity of CAT protein
Dizocilpine Maleate inhibits the reaction [ammonium acetate results in decreased activity of CAT protein]
CTD PMID:12885441, PMID:15945352 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A multiple interactions
decreases expression
EXP Allopurinol inhibits the reaction [ammonium acetate results in decreased expression of GRIN2A protein] CTD PMID:20084674 NCBI chr10:5,707,806...6,123,568
Ensembl chr10:5,930,298...6,119,990
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B decreases expression EXP ammonium acetate results in decreased expression of GRIN2B protein CTD PMID:20084674 NCBI chr 4:169,541,620...170,000,216
Ensembl chr 4:169,560,387...169,999,873
JBrowse link
G Hmox1 heme oxygenase 1 increases expression EXP ammonium acetate results in increased expression of HMOX1 protein CTD PMID:12420312 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Maoa monoamine oxidase A increases activity
multiple interactions
EXP ammonium acetate results in increased activity of MAOA protein
Dizocilpine Maleate inhibits the reaction [ammonium acetate results in increased activity of MAOA protein]
CTD PMID:12885441 NCBI chr  X:6,554,698...6,620,722
Ensembl chr  X:6,554,698...6,620,722
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases expression
multiple interactions
EXP ammonium acetate results in increased expression of PARP1 protein
Cycloheximide inhibits the reaction [ammonium acetate results in increased expression of PARP1 protein]; Dizocilpine Maleate inhibits the reaction [ammonium acetate results in increased expression of PARP1 protein]
CTD PMID:15147502 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Sod2 superoxide dismutase 2 decreases activity
multiple interactions
EXP ammonium acetate results in decreased activity of SOD2 protein
Dizocilpine Maleate inhibits the reaction [ammonium acetate results in decreased activity of SOD2 protein]
CTD PMID:12885441 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Xdh xanthine dehydrogenase affects activity
multiple interactions
EXP ammonium acetate affects the activity of XDH protein
Dizocilpine Maleate inhibits the reaction [ammonium acetate affects the activity of XDH protein]
CTD PMID:12885441 NCBI chr 6:25,149,570...25,211,273
Ensembl chr 6:25,149,235...25,211,494
JBrowse link
cobalt(II) acetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression ISO cobalt(II) acetate results in increased expression of HIF1A protein CTD PMID:16357179 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
lead tetraacetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein decreases expression ISO lead tetraacetate results in decreased expression of APP mRNA CTD PMID:20865013 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Mapt microtubule-associated protein tau decreases expression ISO lead tetraacetate results in decreased expression of MAPT mRNA CTD PMID:20865013 NCBI chr10:92,289,002...92,386,517
Ensembl chr10:92,288,910...92,386,517
JBrowse link
G Nrxn1 neurexin 1 decreases expression ISO lead tetraacetate results in decreased expression of NRXN1 mRNA CTD PMID:20865013 NCBI chr 6:13,886,757...15,191,660
Ensembl chr 6:13,886,740...15,191,660
JBrowse link
G Prnp prion protein decreases expression ISO lead tetraacetate results in decreased expression of PRNP mRNA CTD PMID:20865013 NCBI chr 3:124,515,917...124,531,320
Ensembl chr 3:124,515,978...124,531,316
JBrowse link
G Syp synaptophysin decreases expression ISO lead tetraacetate results in decreased expression of SYP mRNA CTD PMID:20865013 NCBI chr  X:15,694,699...15,709,244
Ensembl chr  X:15,695,566...15,707,436
JBrowse link
G Tubb3 tubulin, beta 3 class III decreases expression ISO lead tetraacetate results in decreased expression of TUBB3 mRNA CTD PMID:20865013 NCBI chr19:56,220,759...56,229,813
Ensembl chr19:56,220,755...56,229,813
JBrowse link
thallium(I) acetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sod1 superoxide dismutase 1 decreases activity EXP thallium acetate results in decreased activity of SOD1 protein CTD PMID:15833379 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
zinc acetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions ISO [ATP7B gene mutant form results in increased susceptibility to Zinc Acetate] promotes the reaction [NR1H4 protein binds to ABCB11 promoter]; [ATP7B gene mutant form results in increased susceptibility to Zinc Acetate] promotes the reaction [RXRA protein binds to ABCB11 promoter]; [ATP7B gene mutant form results in increased susceptibility to Zinc Acetate] which results in increased expression of ABCB11 mRNA CTD PMID:26241054 NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
JBrowse link
G Agl amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase multiple interactions
decreases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of AGL mRNA
Zinc Acetate results in decreased expression of AGL mRNA
CTD PMID:16357179 NCBI chr 2:219,788,234...219,843,189
Ensembl chr 2:219,788,234...219,842,986
JBrowse link
G Alad aminolevulinate dehydratase multiple interactions
increases activity
EXP [Zinc Acetate results in increased activity of ALAD protein] which results in increased chemical synthesis of Porphobilinogen; Zinc Acetate inhibits the reaction [Dithiothreitol results in increased activity of ALAD protein] CTD PMID:21360559 NCBI chr 5:78,368,867...78,379,206
Ensembl chr 5:78,368,867...78,379,346
JBrowse link
G Aldh5a1 aldehyde dehydrogenase 5 family, member A1 multiple interactions
increases expression
ISO motexafin gadolinium inhibits the reaction [Zinc Acetate results in increased expression of ALDH5A1 mRNA] CTD PMID:16357179 NCBI chr17:42,133,076...42,159,413
Ensembl chr17:42,133,076...42,159,413
JBrowse link
G Aldh6a1 aldehyde dehydrogenase 6 family, member A1 multiple interactions
increases expression
ISO Zinc Acetate inhibits the reaction [motexafin gadolinium results in decreased expression of ALDH6A1 mRNA]
Zinc Acetate results in increased expression of ALDH6A1 mRNA
CTD PMID:16357179 NCBI chr 6:108,146,552...108,167,185
Ensembl chr 6:108,146,582...108,167,185
JBrowse link
G Arhgap17 Rho GTPase activating protein 17 multiple interactions
decreases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of ARHGAP17 mRNA
Zinc Acetate results in decreased expression of ARHGAP17 mRNA
CTD PMID:16357179 NCBI chr 1:193,239,036...193,328,425
Ensembl chr 1:193,239,040...193,328,371
JBrowse link
G Atf3 activating transcription factor 3 multiple interactions
increases expression
ISO motexafin gadolinium promotes the reaction [Zinc Acetate results in increased expression of ATF3 mRNA] CTD PMID:16357179 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Atm ATM serine/threonine kinase multiple interactions
increases expression
ISO motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of ATM mRNA] CTD PMID:16357179 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
JBrowse link
G Atp7b ATPase copper transporting beta increases response to substance
multiple interactions
ISO ATP7B gene mutant form results in increased susceptibility to Zinc Acetate
[ATP7B gene mutant form results in increased susceptibility to Zinc Acetate] promotes the reaction [NR1H4 protein binds to ABCB11 promoter]; [ATP7B gene mutant form results in increased susceptibility to Zinc Acetate] promotes the reaction [RXRA protein binds to ABCB11 promoter]; [ATP7B gene mutant form results in increased susceptibility to Zinc Acetate] promotes the reaction [RXRA protein binds to NR0B2 promoter]; [ATP7B gene mutant form results in increased susceptibility to Zinc Acetate] which results in increased expression of ABCB11 mRNA; [ATP7B gene mutant form results in increased susceptibility to Zinc Acetate] which results in increased expression of NR0B2 mRNA; [ATP7B gene mutant form results in increased susceptibility to Zinc Acetate] which results in increased expression of RXRA mRNA
CTD PMID:26241054 NCBI chr16:74,865,516...74,944,935
Ensembl chr16:74,865,516...74,945,286
JBrowse link
G Atr ATR serine/threonine kinase multiple interactions
decreases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of ATR mRNA
Zinc Acetate results in decreased expression of ATR mRNA
CTD PMID:16357179 NCBI chr 8:103,673,578...103,770,886
Ensembl chr 8:103,673,411...103,770,947
JBrowse link
G Bach1 BTB domain and CNC homolog 1 multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of BACH1 mRNA
Zinc Acetate results in increased expression of BACH1 mRNA
CTD PMID:16357179 NCBI chr11:27,364,913...27,398,713
Ensembl chr11:27,364,916...27,398,842
JBrowse link
G Bag3 BAG cochaperone 3 multiple interactions
increases expression
ISO motexafin gadolinium promotes the reaction [Zinc Acetate results in increased expression of BAG3 mRNA] CTD PMID:16357179 NCBI chr 1:199,941,258...199,965,191
Ensembl chr 1:199,941,161...199,965,191
JBrowse link
G Bbc3 Bcl-2 binding component 3 multiple interactions ISO [Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of BBC3 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of BBC3 protein] CTD PMID:20530418 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 increases expression
multiple interactions
ISO Zinc Acetate results in increased expression of BIRC5 mRNA
motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of BIRC5 mRNA]
CTD PMID:16357179 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Bmt2 base methyltransferase of 25S rRNA 2 homolog multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of BMT2 mRNA
Zinc Acetate results in increased expression of BMT2 mRNA
CTD PMID:16357179 NCBI chr 4:40,064,131...40,136,074
Ensembl chr 4:40,063,932...40,136,061
JBrowse link
G Bnip3 BCL2 interacting protein 3 multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of BNIP3 mRNA
Zinc Acetate results in increased expression of BNIP3 mRNA
CTD PMID:16357179 NCBI chr 1:211,248,098...211,265,282
Ensembl chr 1:211,248,098...211,265,282
JBrowse link
G Bnip3l BCL2 interacting protein 3 like multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of BNIP3L mRNA
Zinc Acetate results in increased expression of BNIP3L mRNA
CTD PMID:16357179 NCBI chr15:43,643,897...43,667,123
Ensembl chr15:43,643,897...43,667,029
JBrowse link
G Canx calnexin increases expression
multiple interactions
ISO Zinc Acetate results in increased expression of CANX mRNA
[Zinc Acetate co-treated with motexafin gadolinium] affects the expression of CANX mRNA
CTD PMID:16357179 NCBI chr10:35,800,942...35,833,939
Ensembl chr10:35,800,942...35,833,861
JBrowse link
G Casp3 caspase 3 multiple interactions
decreases expression
EXP
ISO
[Taurine co-treated with Zinc Acetate] inhibits the reaction [Doxorubicin results in increased expression of CASP3 protein]
Zinc Acetate results in decreased expression of CASP3 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CASP3 mRNA
CTD PMID:16357179, PMID:26335259 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cbfb core-binding factor subunit beta increases expression
multiple interactions
ISO Zinc Acetate results in increased expression of CBFB mRNA
[Zinc Acetate co-treated with motexafin gadolinium] affects the expression of CBFB mRNA
CTD PMID:16357179 NCBI chr19:37,127,508...37,171,075
Ensembl chr19:37,127,508...37,171,069
JBrowse link
G Ccnj cyclin J multiple interactions
decreases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CCNJ mRNA
Zinc Acetate results in decreased expression of CCNJ mRNA
CTD PMID:16357179 NCBI chr 1:259,926,537...259,944,275
Ensembl chr 1:260,093,641...260,111,254
Ensembl chr 1:260,093,641...260,111,254
JBrowse link
G Cdc16 cell division cycle 16 multiple interactions
decreases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CDC16 mRNA
Zinc Acetate results in decreased expression of CDC16 mRNA
CTD PMID:16357179 NCBI chr16:81,493,355...81,516,493
Ensembl chr16:81,493,355...81,516,493
JBrowse link
G Cdc25c cell division cycle 25C multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of CDC25C mRNA
Zinc Acetate results in increased expression of CDC25C mRNA
CTD PMID:16357179 NCBI chr18:27,528,768...27,550,316
Ensembl chr18:27,528,354...27,550,224
JBrowse link
G Cdc27 cell division cycle 27 increases expression
multiple interactions
ISO Zinc Acetate results in increased expression of CDC27 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] affects the expression of CDC27 mRNA
CTD PMID:16357179 NCBI chr10:92,551,754...92,602,214
Ensembl chr10:92,554,081...92,602,082
JBrowse link
G Cdc5l cell division cycle 5-like decreases expression
multiple interactions
ISO Zinc Acetate results in decreased expression of CDC5L mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CDC5L mRNA
CTD PMID:16357179 NCBI chr 9:17,949,764...17,988,514
Ensembl chr 9:17,949,764...17,988,509
JBrowse link
G Cdca2 cell division cycle associated 2 multiple interactions
decreases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CDCA2 mRNA
Zinc Acetate results in decreased expression of CDCA2 mRNA
CTD PMID:16357179 NCBI chr15:44,365,396...44,411,601
Ensembl chr15:44,365,405...44,411,004
JBrowse link
G Cdk19 cyclin-dependent kinase 19 increases expression ISO Zinc Acetate results in increased expression of CDK19 mRNA CTD PMID:16357179 NCBI chr20:45,458,499...45,598,799
Ensembl chr20:45,458,558...45,598,798
JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions
increases expression
ISO motexafin gadolinium inhibits the reaction [Zinc Acetate results in increased expression of CDK2 mRNA] CTD PMID:16357179 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO [Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CDKN1A mRNA; nutlin 3 inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CDKN1A mRNA] CTD PMID:20530418 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of CDKN1B mRNA
Zinc Acetate results in increased expression of CDKN1B mRNA
CTD PMID:16357179 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cth cystathionine gamma-lyase increases expression
multiple interactions
ISO Zinc Acetate results in increased expression of CTH mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of CTH mRNA
CTD PMID:16357179 NCBI chr 2:264,266,959...264,293,040
Ensembl chr 2:264,266,984...264,293,046
JBrowse link
G Cul3 cullin 3 multiple interactions
decreases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CUL3 mRNA
Zinc Acetate results in decreased expression of CUL3 mRNA
CTD PMID:16357179 NCBI chr 9:86,044,485...86,129,066
Ensembl chr 9:86,044,485...86,129,329
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 increases secretion ISO Zinc Acetate results in increased secretion of CXCL1 protein CTD PMID:21974847 NCBI chr14:18,743,678...18,745,457
Ensembl chr14:18,743,685...18,745,457
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 increases secretion ISO Zinc Acetate results in increased secretion of CXCL1 protein CTD PMID:21974847 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
JBrowse link
G Cyb5r1 cytochrome b5 reductase 1 increases expression
multiple interactions
ISO Zinc Acetate results in increased expression of CYB5R1 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of CYB5R1 mRNA
CTD PMID:16357179 NCBI chr13:51,229,697...51,236,447
Ensembl chr13:51,229,890...51,236,463
JBrowse link
G Dapk3 death-associated protein kinase 3 increases expression
multiple interactions
ISO Zinc Acetate results in increased expression of DAPK3 mRNA
motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of DAPK3 mRNA]
CTD PMID:16357179 NCBI chr 7:11,392,436...11,400,855
Ensembl chr 7:11,392,437...11,400,805
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression
ISO motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of DDIT3 mRNA] CTD PMID:16357179 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 multiple interactions
increases expression
ISO motexafin gadolinium promotes the reaction [Zinc Acetate results in increased expression of DDIT4 mRNA]; Zinc Acetate promotes the reaction [motexafin gadolinium results in increased expression of DDIT4 mRNA] CTD PMID:16357179 NCBI chr20:29,509,283...29,511,382
Ensembl chr20:29,509,289...29,511,382
JBrowse link
G Dedd2 death effector domain containing 2 increases expression
multiple interactions
ISO Zinc Acetate results in increased expression of DEDD2 mRNA
motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of DEDD2 mRNA]
CTD PMID:16357179 NCBI chr 1:82,073,024...82,089,028
Ensembl chr 1:82,072,544...82,088,275
JBrowse link
G Dffb DNA fragmentation factor subunit beta multiple interactions
decreases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of DFFB mRNA
Zinc Acetate results in decreased expression of DFFB mRNA
CTD PMID:16357179 NCBI chr 5:171,250,559...171,261,875
Ensembl chr 5:171,249,633...171,262,119
JBrowse link
G Dhcr7 7-dehydrocholesterol reductase decreases expression ISO Zinc Acetate results in decreased expression of DHCR7 mRNA CTD PMID:16357179 NCBI chr 1:217,018,916...217,034,890
Ensembl chr 1:217,018,916...217,034,904
JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 decreases expression
multiple interactions
ISO Zinc Acetate results in decreased expression of DNAJB1 mRNA
motexafin gadolinium inhibits the reaction [Zinc Acetate results in decreased expression of DNAJB1 mRNA]
CTD PMID:16357179 NCBI chr19:24,747,178...24,750,919
Ensembl chr19:24,747,178...24,750,919
JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of DNAJB4 mRNA
Zinc Acetate results in increased expression of DNAJB4 mRNA
CTD PMID:16357179 NCBI chr 2:257,394,692...257,425,344
Ensembl chr 2:257,394,818...257,425,242
JBrowse link
G Dnajb6 DnaJ heat shock protein family (Hsp40) member B6 multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of DNAJB6 mRNA
Zinc Acetate results in increased expression of DNAJB6 mRNA
CTD PMID:16357179 NCBI chr 4:2,711,329...2,774,969
Ensembl chr 4:2,711,385...2,774,890
JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 multiple interactions
increases expression
ISO motexafin gadolinium inhibits the reaction [Zinc Acetate results in increased expression of DNAJC3 mRNA] CTD PMID:16357179 NCBI chr15:104,186,918...104,226,236
Ensembl chr15:104,186,792...104,226,329
JBrowse link
G Drd1 dopamine receptor D1 multiple interactions EXP Zinc Acetate inhibits the reaction [SCH 23390 binds to DRD1 protein] CTD PMID:9109525 NCBI chr17:11,099,736...11,104,352
Ensembl chr17:11,101,306...11,103,541
JBrowse link
G Drd2 dopamine receptor D2 multiple interactions EXP Zinc Acetate inhibits the reaction [3-N-methylspiperone binds to DRD2 protein] CTD PMID:9109525 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Dusp1 dual specificity phosphatase 1 multiple interactions EXP [Taurine co-treated with Zinc Acetate] results in increased expression of DUSP1 mRNA; [Taurine co-treated with Zinc Acetate] results in increased expression of DUSP1 protein CTD PMID:26335259 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G E2f1 E2F transcription factor 1 increases expression
multiple interactions
ISO Zinc Acetate results in increased expression of E2F1 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of E2F1 mRNA
CTD PMID:16357179 NCBI chr 3:150,062,895...150,073,721
Ensembl chr 3:150,047,826...150,073,721
JBrowse link
G E2f3 E2F transcription factor 3 multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of E2F3 mRNA
Zinc Acetate results in increased expression of E2F3 mRNA
CTD PMID:16357179 NCBI chr17:36,334,136...36,408,831
Ensembl chr17:36,334,147...36,408,831
JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 increases expression
multiple interactions
ISO Zinc Acetate results in increased expression of EGLN1 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of EGLN1 mRNA
CTD PMID:16357179 NCBI chr19:57,660,194...57,701,158
Ensembl chr19:57,662,278...57,699,113
JBrowse link
G Elp1 elongator complex protein 1 multiple interactions
decreases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of ELP1 mRNA
Zinc Acetate results in decreased expression of ELP1 mRNA
CTD PMID:16357179 NCBI chr 5:73,503,406...73,552,798
Ensembl chr 5:73,503,407...73,552,798
JBrowse link
G Eno1 enolase 1 increases expression ISO Zinc Acetate results in increased expression of ENO1 mRNA CTD PMID:16357179 NCBI chr 5:167,288,223...167,299,610
Ensembl chr 5:167,288,223...167,299,609
JBrowse link
G Fadd Fas associated via death domain multiple interactions
decreases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of FADD mRNA
Zinc Acetate results in decreased expression of FADD mRNA
CTD PMID:16357179 NCBI chr 1:217,746,176...217,748,581
Ensembl chr 1:217,742,929...217,748,628
JBrowse link
G Faim Fas apoptotic inhibitory molecule multiple interactions
decreases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of FAIM mRNA
Zinc Acetate results in decreased expression of FAIM mRNA
CTD PMID:16357179 NCBI chr 8:107,225,119...107,247,228
Ensembl chr 8:107,225,212...107,241,224
Ensembl chr 8:107,225,212...107,241,224
JBrowse link
G Fam162a family with sequence similarity 162, member A multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of FAM162A mRNA
Zinc Acetate results in increased expression of FAM162A mRNA
CTD PMID:16357179 NCBI chr11:67,618,683...67,646,253
Ensembl chr11:67,618,625...67,646,253
JBrowse link
G Fasn fatty acid synthase decreases expression ISO Zinc Acetate results in decreased expression of FASN mRNA CTD PMID:16357179 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Foxo3 forkhead box O3 multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of FOXO3 mRNA
Zinc Acetate results in increased expression of FOXO3 mRNA
CTD PMID:16357179 NCBI chr20:46,428,078...46,519,156
Ensembl chr20:46,428,124...46,519,144
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression
multiple interactions
ISO Zinc Acetate results in increased expression of GCLM mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of GCLM mRNA
CTD PMID:16357179 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Gls glutaminase multiple interactions
decreases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of GLS mRNA
Zinc Acetate results in decreased expression of GLS mRNA
CTD PMID:16357179 NCBI chr 9:54,212,622...54,284,879
Ensembl chr 9:54,212,767...54,284,872
JBrowse link
G Gpr146 G protein-coupled receptor 146 increases expression ISO Zinc Acetate results in increased expression of GPR146 mRNA CTD PMID:16357179 NCBI chr12:17,343,396...17,358,631
Ensembl chr12:17,345,510...17,358,617
JBrowse link
G Gpt2 glutamic--pyruvic transaminase 2 increases expression ISO Zinc Acetate results in increased expression of GPT2 mRNA CTD PMID:16357179 NCBI chr19:22,599,003...22,633,529
Ensembl chr19:22,590,881...22,632,071
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions ISO [Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of GPX1 mRNA; nutlin 3 inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of GPX1 mRNA] CTD PMID:20530418 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions
decreases activity
increases expression
ISO
EXP
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of GSR mRNA
Zinc Acetate results in decreased activity of GSR protein
Zinc Acetate results in increased expression of GSR mRNA
CTD PMID:16357179, PMID:17382203 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gtf3c2 general transcription factor IIIC subunit 2 increases expression ISO Zinc Acetate results in increased expression of GTF3C2 mRNA CTD PMID:16357179 NCBI chr 6:26,560,601...26,584,533
Ensembl chr 6:26,560,601...26,584,535
JBrowse link
G Hbp1 HMG-box transcription factor 1 increases expression
multiple interactions
ISO Zinc Acetate results in increased expression of HBP1 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of HBP1 mRNA
CTD PMID:16357179 NCBI chr 6:51,231,479...51,257,699
Ensembl chr 6:51,231,480...51,257,625
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions
increases expression
ISO [motexafin gadolinium co-treated with Zinc Acetate] results in increased expression of HIF1A protein
Zinc Acetate results in increased expression of HIF1A protein
CTD PMID:16357179 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hilpda hypoxia inducible lipid droplet-associated multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of HILPDA mRNA
Zinc Acetate results in increased expression of HILPDA mRNA
CTD PMID:16357179 NCBI chr 4:56,547,600...56,550,584
Ensembl chr 4:56,549,739...56,549,993
JBrowse link
G Hipk1 homeodomain interacting protein kinase 1 multiple interactions
increases expression
ISO motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of HIPK1 mRNA] CTD PMID:16357179 NCBI chr 2:206,224,015...206,274,910
Ensembl chr 2:206,224,015...206,274,079
JBrowse link
G Hltf helicase-like transcription factor multiple interactions
decreases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of HLTF mRNA
Zinc Acetate results in decreased expression of HLTF mRNA
CTD PMID:16357179 NCBI chr 2:104,854,571...104,914,338
Ensembl chr 2:104,854,572...104,914,173
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO
EXP
[motexafin gadolinium co-treated with Zinc Acetate] results in increased expression of HMOX1 protein; motexafin gadolinium promotes the reaction [Zinc Acetate results in increased expression of HMOX1 mRNA]
[Taurine co-treated with Zinc Acetate] results in increased expression of HMOX1 protein
CTD PMID:16357179, PMID:26335259 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hrk harakiri, BCL2 interacting protein increases expression
multiple interactions
ISO Zinc Acetate results in increased expression of HRK mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of HRK mRNA
CTD PMID:16357179 NCBI chr12:44,008,879...44,029,211 JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of HSP90AB1 mRNA
Zinc Acetate results in increased expression of HSP90AB1 mRNA
CTD PMID:16357179 NCBI chr 9:17,817,791...17,823,163
Ensembl chr 9:17,817,721...17,823,243
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A multiple interactions
increases expression
ISO motexafin gadolinium promotes the reaction [Zinc Acetate results in increased expression of HSPA1A mRNA]; Zinc Acetate promotes the reaction [motexafin gadolinium results in increased expression of HSPA1A mRNA] CTD PMID:16357179 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B multiple interactions
increases expression
ISO motexafin gadolinium promotes the reaction [Zinc Acetate results in increased expression of HSPA1B mRNA]; Zinc Acetate promotes the reaction [motexafin gadolinium results in increased expression of HSPA1B mRNA] CTD PMID:16357179 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of HSPA4 mRNA
Zinc Acetate results in increased expression of HSPA4 mRNA
CTD PMID:16357179 NCBI chr10:38,601,624...38,642,397
Ensembl chr10:38,601,624...38,642,397
JBrowse link
G Hspa4l heat shock protein family A (Hsp70) member 4 like multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of HSPA4L mRNA
Zinc Acetate results in increased expression of HSPA4L mRNA
CTD PMID:16357179 NCBI chr 2:127,625,737...127,682,864
Ensembl chr 2:127,625,683...127,677,503
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 multiple interactions
increases expression
ISO motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of HSPB1 mRNA] CTD PMID:16357179 NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 multiple interactions
increases expression
ISO motexafin gadolinium promotes the reaction [Zinc Acetate results in increased expression of HSPD1 mRNA] CTD PMID:16357179 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 multiple interactions
increases expression
ISO motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of HSPH1 mRNA] CTD PMID:16357179 NCBI chr12:6,322,685...6,341,898
Ensembl chr12:6,322,668...6,341,902
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions
increases expression
ISO 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Zinc Acetate results in increased expression of ICAM1 protein]; [Zinc Acetate results in increased phosphorylation of NFKBIA protein] inhibits the reaction [Zinc Acetate results in increased expression of ICAM1 protein]; MYD88 mutant form inhibits the reaction [Zinc Acetate results in increased expression of ICAM1 protein] CTD PMID:24080332 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Id2 inhibitor of DNA binding 2 multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of ID2 mRNA
Zinc Acetate results in increased expression of ID2 mRNA
CTD PMID:16357179 NCBI chr 6:44,360,077...44,361,908
Ensembl chr 6:44,348,501...44,363,915
JBrowse link
G Ikbke inhibitor of nuclear factor kappa B kinase subunit epsilon multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of IKBKE mRNA
Zinc Acetate results in increased expression of IKBKE mRNA
CTD PMID:16357179 NCBI chr13:48,031,325...48,056,394
Ensembl chr13:48,031,410...48,056,394
JBrowse link
G Il10 interleukin 10 increases secretion ISO Zinc Acetate results in increased secretion of IL10 protein CTD PMID:21974847 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP [Taurine co-treated with Zinc Acetate] results in decreased expression of IL1B protein CTD PMID:27501764 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 increases secretion ISO Zinc Acetate results in increased secretion of IL6 protein CTD PMID:21974847 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Il7 interleukin 7 increases secretion ISO Zinc Acetate results in increased secretion of IL7 protein CTD PMID:21974847 NCBI chr 2:96,427,884...96,474,979
Ensembl chr 2:96,439,286...96,474,977
JBrowse link
G Irf2bp2 interferon regulatory factor 2 binding protein 2 multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of IRF2BP2 mRNA
Zinc Acetate results in increased expression of IRF2BP2 mRNA
CTD PMID:16357179 NCBI chr19:59,497,021...59,502,298
Ensembl chr19:59,499,876...59,502,161
JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of JUND mRNA
Zinc Acetate results in increased expression of JUND mRNA
CTD PMID:16357179 NCBI chr16:20,485,028...20,486,707
Ensembl chr16:20,485,029...20,486,707
JBrowse link
G Kdm3a lysine demethylase 3A increases expression ISO Zinc Acetate results in increased expression of KDM3A mRNA CTD PMID:16357179 NCBI chr 4:99,503,160...99,547,315
Ensembl chr 4:99,503,176...99,546,905
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions EXP [Taurine co-treated with Zinc Acetate] results in decreased expression of MAPK8 protein modified form CTD PMID:27501764 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions EXP [Taurine co-treated with Zinc Acetate] results in decreased expression of MAPK9 protein modified form CTD PMID:27501764 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Mapt microtubule-associated protein tau multiple interactions ISO [Zinc Acetate results in decreased abundance of Copper] which results in decreased phosphorylation of MAPT protein CTD PMID:25671100 NCBI chr10:92,289,002...92,386,517
Ensembl chr10:92,288,910...92,386,517
JBrowse link
G Mdm2 MDM2 proto-oncogene multiple interactions
increases expression
ISO motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of MDM2 mRNA] CTD PMID:16357179 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Mob1a MOB kinase activator 1A increases expression
multiple interactions
ISO Zinc Acetate results in increased expression of MOB1A mRNA
motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of MOB1A mRNA]
CTD PMID:16357179 NCBI chr 4:115,024,927...115,041,904
Ensembl chr 4:115,024,927...115,041,899
JBrowse link
G Mt1 metallothionein 1 increases expression ISO Zinc Acetate results in increased expression of MT1 protein CTD PMID:15306638 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
JBrowse link
G Mt2A metallothionein 2A increases expression
multiple interactions
ISO Zinc Acetate results in increased expression of MT2 mRNA; Zinc Acetate results in increased expression of MT2 protein
Zinc Acetate results in increased expression of MT2A mRNA
motexafin gadolinium promotes the reaction [Zinc Acetate results in increased expression of MT2A mRNA]
CTD PMID:8876661, PMID:15306638, PMID:16357179 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor multiple interactions
decreases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of MYD88 mRNA; MYD88 mutant form inhibits the reaction [Zinc Acetate results in increased expression of CXCL8 protein]; MYD88 mutant form inhibits the reaction [Zinc Acetate results in increased expression of ICAM1 protein]
Zinc Acetate results in decreased expression of MYD88 mRNA
CTD PMID:16357179, PMID:24080332 NCBI chr 8:128,022,512...128,027,462
Ensembl chr 8:128,022,473...128,026,841
JBrowse link
G Nadk NAD kinase multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of NADK mRNA
Zinc Acetate results in increased expression of NADK mRNA
CTD PMID:16357179 NCBI chr 5:172,984,930...173,015,505
Ensembl chr 5:172,986,291...173,015,494
JBrowse link
G Nf1 neurofibromin 1 increases expression
multiple interactions
ISO Zinc Acetate results in increased expression of NF1 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of NF1 mRNA
CTD PMID:16357179 NCBI chr10:66,732,460...66,928,706
Ensembl chr10:66,690,133...66,928,903
JBrowse link
G Nfkbia NFKB inhibitor alpha increases degradation
multiple interactions
increases phosphorylation
ISO Zinc Acetate results in increased degradation of NFKBIA protein
[Zinc Acetate results in increased phosphorylation of NFKBIA protein] inhibits the reaction [Zinc Acetate results in increased expression of ICAM1 protein]
CTD PMID:21974847, PMID:24080332 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nisch nischarin decreases expression ISO Zinc Acetate results in decreased expression of NISCH mRNA CTD PMID:16357179 NCBI chr16:7,254,372...7,290,670
Ensembl chr16:7,254,974...7,290,561
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 multiple interactions ISO [ATP7B gene mutant form results in increased susceptibility to Zinc Acetate] promotes the reaction [RXRA protein binds to NR0B2 promoter]; [ATP7B gene mutant form results in increased susceptibility to Zinc Acetate] which results in increased expression of NR0B2 mRNA CTD PMID:26241054 NCBI chr 5:151,776,004...151,779,319
Ensembl chr 5:151,776,004...151,779,319
JBrowse link
G Nr1d2 nuclear receptor subfamily 1, group D, member 2 multiple interactions
increases expression
ISO motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of NR1D2 mRNA] CTD PMID:16357179 NCBI chr15:8,730,871...8,757,165
Ensembl chr15:8,730,871...8,757,165
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO [ATP7B gene mutant form results in increased susceptibility to Zinc Acetate] promotes the reaction [NR1H4 protein binds to ABCB11 promoter] CTD PMID:26241054 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
G P4hb prolyl 4-hydroxylase subunit beta multiple interactions
increases expression
ISO motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of P4HB mRNA] CTD PMID:16357179 NCBI chr10:109,736,459...109,748,070
Ensembl chr10:109,736,458...109,747,987
JBrowse link
G Pdcd11 programmed cell death 11 decreases expression ISO Zinc Acetate results in decreased expression of PDCD11 mRNA CTD PMID:16357179 NCBI chr 1:266,866,931...266,908,042
Ensembl chr 1:266,866,931...266,908,042
JBrowse link
G Pdcd4 programmed cell death 4 multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of PDCD4 mRNA
Zinc Acetate results in increased expression of PDCD4 mRNA
CTD PMID:16357179 NCBI chr 1:274,616,625...274,648,204
Ensembl chr 1:274,625,224...274,648,204
JBrowse link
G Pdcd5 programmed cell death 5 multiple interactions
decreases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of PDCD5 mRNA
Zinc Acetate results in decreased expression of PDCD5 mRNA
CTD PMID:16357179 NCBI chr 1:91,173,473...91,178,801
Ensembl chr 1:91,173,473...91,178,801
Ensembl chr 1:91,173,473...91,178,801
JBrowse link
G Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of PFKFB3 mRNA
Zinc Acetate results in increased expression of PFKFB3 mRNA
CTD PMID:16357179 NCBI chr17:70,632,778...70,713,736
Ensembl chr17:70,684,134...70,713,726
JBrowse link
G Pfkfb4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of PFKFB4 mRNA
Zinc Acetate results in increased expression of PFKFB4 mRNA
CTD PMID:16357179 NCBI chr 8:117,733,347...117,776,525
Ensembl chr 8:117,737,117...117,775,386
JBrowse link
G Pgk1 phosphoglycerate kinase 1 increases expression
multiple interactions
ISO Zinc Acetate results in increased expression of PGK1 mRNA
motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of PGK1 mRNA]
CTD PMID:16357179 NCBI chr  X:77,263,399...77,279,373
Ensembl chr  X:77,263,359...77,279,367
JBrowse link
G Phtf2 putative homeodomain transcription factor 2 multiple interactions
increases expression
ISO motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of PHTF2 mRNA] CTD PMID:16357179 NCBI chr 4:10,823,191...10,938,273
Ensembl chr 4:10,823,281...10,938,318
JBrowse link
G Pias1 protein inhibitor of activated STAT, 1 multiple interactions
increases expression
ISO motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of PIAS1 mRNA] CTD PMID:16357179 NCBI chr 8:67,771,720...67,869,015
Ensembl chr 8:67,771,720...67,869,019
JBrowse link
G Pik3ip1 phosphoinositide-3-kinase interacting protein 1 multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of PIK3IP1 mRNA
Zinc Acetate results in increased expression of PIK3IP1 mRNA
CTD PMID:16357179 NCBI chr14:83,559,397...83,572,481
Ensembl chr14:83,560,541...83,572,473
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression
multiple interactions
ISO Zinc Acetate results in increased expression of PMAIP1 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of PMAIP1 mRNA
CTD PMID:16357179 NCBI chr18:62,159,128...62,179,635
Ensembl chr18:62,174,670...62,181,102
JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of PRKACB mRNA
Zinc Acetate results in increased expression of PRKACB mRNA
CTD PMID:16357179 NCBI chr 2:252,602,197...252,691,886
Ensembl chr 2:252,605,307...252,691,886
JBrowse link
G Prkcd protein kinase C, delta decreases expression ISO Zinc Acetate results in decreased expression of PRKCD mRNA CTD PMID:16357179 NCBI chr16:6,655,131...6,675,746
Ensembl chr16:6,655,120...6,675,746
JBrowse link
G Prkd2 protein kinase D2 decreases expression ISO Zinc Acetate results in decreased expression of PRKD2 mRNA CTD PMID:16357179 NCBI chr 1:78,767,911...78,796,223
Ensembl chr 1:78,767,911...78,796,231
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit increases expression ISO Zinc Acetate results in increased expression of PRKDC mRNA CTD PMID:16357179 NCBI chr11:89,293,547...89,510,948
Ensembl chr11:89,293,696...89,510,871
JBrowse link
G Ptrh2 peptidyl-tRNA hydrolase 2 multiple interactions
decreases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of PTRH2 mRNA
Zinc Acetate results in decreased expression of PTRH2 mRNA
CTD PMID:16357179 NCBI chr10:74,002,151...74,012,182
Ensembl chr10:74,002,151...74,012,159
JBrowse link
G Rb1 RB transcriptional corepressor 1 multiple interactions
decreases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of RB1 mRNA
Zinc Acetate results in decreased expression of RB1 mRNA
CTD PMID:16357179 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
JBrowse link
G Rcbtb2 RCC1 and BTB domain containing protein 2 multiple interactions
decreases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of RCBTB2 mRNA
Zinc Acetate results in decreased expression of RCBTB2 mRNA
CTD PMID:16357179 NCBI chr15:55,029,388...55,074,728
Ensembl chr15:55,034,033...55,073,437
JBrowse link
G Relb RELB proto-oncogene, NF-kB subunit multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of RELB mRNA
Zinc Acetate results in increased expression of RELB mRNA
CTD PMID:16357179 NCBI chr 1:80,517,081...80,545,019
Ensembl chr 1:80,517,411...80,544,825
JBrowse link
G Rxra retinoid X receptor alpha multiple interactions ISO [ATP7B gene mutant form results in increased susceptibility to Zinc Acetate] promotes the reaction [RXRA protein binds to ABCB11 promoter]; [ATP7B gene mutant form results in increased susceptibility to Zinc Acetate] promotes the reaction [RXRA protein binds to NR0B2 promoter]; [ATP7B gene mutant form results in increased susceptibility to Zinc Acetate] which results in increased expression of RXRA mRNA CTD PMID:26241054 NCBI chr 3:6,272,560...6,295,354
Ensembl chr 3:6,211,789...6,295,908
JBrowse link
G Selenow selenoprotein W multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of SELENOW mRNA
Zinc Acetate results in increased expression of SELENOW mRNA
CTD PMID:16357179 NCBI chr 1:77,530,692...77,535,765
Ensembl chr 1:77,533,148...77,535,681
Ensembl chr 1:77,533,148...77,535,681
JBrowse link
G Sesn2 sestrin 2 multiple interactions
increases expression
ISO [Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of SESN2 mRNA; [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of SESN2 mRNA; nutlin 3 inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of SESN2 mRNA]
Zinc Acetate results in increased expression of SESN2 mRNA
CTD PMID:16357179, PMID:20530418 NCBI chr 5:150,684,891...150,703,846
Ensembl chr 5:150,684,133...150,704,117
JBrowse link
G Slc16a1 solute carrier family 16 member 1 multiple interactions
increases expression
ISO motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of SLC16A1 mRNA] CTD PMID:16357179 NCBI chr 2:207,108,552...207,129,352
Ensembl chr 2:207,108,552...207,128,554
JBrowse link
G Slc16a6 solute carrier family 16, member 6 increases expression
multiple interactions
ISO Zinc Acetate results in increased expression of SLC16A6 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of SLC16A6 mRNA
CTD PMID:16357179 NCBI chr10:97,733,701...97,758,723
Ensembl chr10:97,735,548...97,756,521
JBrowse link
G Slc1a4 solute carrier family 1 member 4 increases expression
multiple interactions
ISO Zinc Acetate results in increased expression of SLC1A4 mRNA
motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of SLC1A4 mRNA]
CTD PMID:16357179 NCBI chr14:104,582,884...104,612,417
Ensembl chr14:104,581,190...104,612,597
JBrowse link
G Slc30a1 solute carrier family 30 member 1 multiple interactions
increases expression
ISO motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of SLC30A1 mRNA]; Zinc Acetate affects the reaction [motexafin gadolinium results in increased expression of SLC30A1 mRNA] CTD PMID:16357179 NCBI chr13:110,677,810...110,681,683
Ensembl chr13:110,677,810...110,681,683
JBrowse link
G Slc31a1 solute carrier family 31 member 1 increases expression ISO Zinc Acetate results in increased expression of SLC31A1 mRNA CTD PMID:24132751 NCBI chr 5:78,222,504...78,249,358
Ensembl chr 5:78,222,504...78,249,358
JBrowse link
G Slc38a2 solute carrier family 38, member 2 multiple interactions
increases expression
ISO motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of SLC38A2 mRNA]; Zinc Acetate affects the reaction [motexafin gadolinium results in increased expression of SLC38A2 mRNA] CTD PMID:16357179 NCBI chr 7:138,088,654...138,100,869
Ensembl chr 7:138,088,649...138,100,841
JBrowse link
G Slc39a10 solute carrier family 39 member 10 affects expression
multiple interactions
ISO Zinc Acetate affects the expression of SLC39A10 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] affects the expression of SLC39A10 mRNA
CTD PMID:16357179 NCBI chr 9:59,947,562...60,070,549
Ensembl chr 9:60,021,534...60,070,552
JBrowse link
G Slc39a14 solute carrier family 39 member 14 multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] affects the expression of SLC39A14 mRNA
Zinc Acetate results in increased expression of SLC39A14 mRNA
CTD PMID:16357179 NCBI chr15:51,982,872...52,029,841
Ensembl chr15:51,982,982...52,029,816
JBrowse link
G Slc39a9 solute carrier family 39, member 9 multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of SLC39A9 mRNA
Zinc Acetate results in increased expression of SLC39A9 mRNA
CTD PMID:16357179 NCBI chr 6:104,291,001...104,326,553
Ensembl chr 6:104,291,071...104,329,872
JBrowse link
G Slc3a2 solute carrier family 3 member 2 multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] affects the expression of SLC3A2 mRNA
Zinc Acetate results in increased expression of SLC3A2 mRNA
CTD PMID:16357179 NCBI chr 1:224,906,566...224,921,029
Ensembl chr 1:224,906,554...224,921,092
JBrowse link
G Slc43a1 solute carrier family 43 member 1 multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of SLC43A1 mRNA
Zinc Acetate results in increased expression of SLC43A1 mRNA
CTD PMID:16357179 NCBI chr 3:72,238,796...72,265,023
Ensembl chr 3:72,238,981...72,264,466
JBrowse link
G Slc7a1 solute carrier family 7 member 1 multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] affects the expression of SLC7A1 mRNA
Zinc Acetate results in increased expression of SLC7A1 mRNA
CTD PMID:16357179 NCBI chr12:8,032,775...8,108,972
Ensembl chr12:8,032,809...8,108,972
JBrowse link
G Slc7a11 solute carrier family 7 member 11 multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] affects the expression of SLC7A11 mRNA
Zinc Acetate results in increased expression of SLC7A11 mRNA
CTD PMID:16357179 NCBI chr 2:139,453,774...139,528,479
Ensembl chr 2:139,453,774...139,528,162
JBrowse link
G Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 multiple interactions
decreases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of SMARCA4 mRNA
Zinc Acetate results in decreased expression of SMARCA4 mRNA
CTD PMID:16357179 NCBI chr 8:22,648,323...22,739,468
Ensembl chr 8:22,648,323...22,739,468
JBrowse link
G Smarca5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 multiple interactions
decreases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of SMARCA5 mRNA
Zinc Acetate results in decreased expression of SMARCA5 mRNA
CTD PMID:16357179 NCBI chr19:30,936,703...30,969,454
Ensembl chr19:30,936,703...30,969,454
JBrowse link
G Sp1 Sp1 transcription factor increases expression ISO Zinc Acetate results in increased expression of SP1 mRNA CTD PMID:24132751 NCBI chr 7:144,014,173...144,044,635
Ensembl chr 7:144,014,173...144,044,629
JBrowse link
G Tagap T-cell activation RhoGTPase activating protein multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of TAGAP mRNA
Zinc Acetate results in increased expression of TAGAP mRNA
CTD PMID:16357179 NCBI chr 1:47,493,990...47,503,492
Ensembl chr 1:47,493,994...47,502,952
JBrowse link
G Tfrc transferrin receptor multiple interactions
increases expression
ISO motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of TFRC mRNA] CTD PMID:16357179 NCBI chr11:71,397,423...71,419,263
Ensembl chr11:71,397,383...71,419,223
JBrowse link
G Tnfaip8 TNF alpha induced protein 8 decreases expression
multiple interactions
ISO Zinc Acetate results in decreased expression of TNFAIP8 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TNFAIP8 mRNA
CTD PMID:16357179 NCBI chr18:44,664,310...44,779,914
Ensembl chr18:44,716,226...44,779,914
JBrowse link
G Tnfrsf17 TNF receptor superfamily member 17 multiple interactions
decreases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TNFRSF17 mRNA
Zinc Acetate results in decreased expression of TNFRSF17 mRNA
CTD PMID:16357179 NCBI chr10:4,252,097...4,258,335
Ensembl chr10:4,251,941...4,257,868
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A increases expression
multiple interactions
ISO Zinc Acetate results in increased expression of TNFRSF1A mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of TNFRSF1A mRNA
CTD PMID:16357179 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Tnfsf8 TNF superfamily member 8 multiple interactions
increases expression
ISO motexafin gadolinium inhibits the reaction [Zinc Acetate results in increased expression of TNFSF8 mRNA] CTD PMID:16357179 NCBI chr 5:79,664,779...79,691,547
Ensembl chr 5:79,664,765...79,691,258
JBrowse link
G Tnip2 TNFAIP3 interacting protein 2 decreases expression ISO Zinc Acetate results in decreased expression of TNIP2 mRNA CTD PMID:16357179 NCBI chr14:81,487,934...81,505,889
Ensembl chr14:81,488,008...81,504,686
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO [Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TP53 protein; Acetylcysteine inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TP53 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TP53 protein]; nutlin 3 inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TP53 protein] CTD PMID:20530418 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Trib3 tribbles pseudokinase 3 multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of TRIB3 mRNA
Zinc Acetate results in increased expression of TRIB3 mRNA
CTD PMID:16357179 NCBI chr 3:147,814,056...147,819,650
Ensembl chr 3:147,813,473...147,819,571
JBrowse link
G Txnrd1 thioredoxin reductase 1 multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of TXNRD1 mRNA
Zinc Acetate results in increased expression of TXNRD1 mRNA
CTD PMID:16357179 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
JBrowse link
G Ugt2b17 UDP glucuronosyltransferase family 2 member B17 multiple interactions EXP [Taurine co-treated with Zinc Acetate] results in increased expression of UGT2B1 mRNA CTD PMID:26335259 NCBI chr14:22,724,399...22,736,148
Ensembl chr14:22,724,070...22,825,444
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions
increases expression
ISO [Zinc Acetate co-treated with motexafin gadolinium] affects the expression of VEGFA mRNA
Zinc Acetate results in increased expression of VEGFA mRNA
CTD PMID:16357179 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Vhl von Hippel-Lindau tumor suppressor increases expression
multiple interactions
ISO Zinc Acetate results in increased expression of VHL mRNA
motexafin gadolinium inhibits the reaction [Zinc Acetate results in increased expression of VHL mRNA]
CTD PMID:16357179 NCBI chr 4:145,580,869...145,587,835
Ensembl chr 4:145,580,799...145,587,845
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19792
    chemical entity 19791
      molecular entity 19787
        ion 15930
          cation 15766
            salt 14624
              organic salt 2359
                acetate salt 174
                  (2S)-2-Ethylhexyl acetate 0
                  1-dodecylguanidine acetate 0
                  L-arginyl-L-glutamic acid monoacetate 0
                  ammonium acetate 13
                  caspofungin acetate 0
                  ceftaroline fosamil acetate + 0
                  cetrorelix acetate 0
                  cobalt(II) acetate 1
                  desmopressin acetate (anhydrous) + 0
                  flecainide acetate 0
                  histrelin acetate 0
                  icatibant acetate 0
                  lead tetraacetate 6
                  leuprolide acetate 0
                  lithium acetate 0
                  peginesatide acetate 0
                  praseodymium acetate 0
                  saxitoxin acetate 0
                  thallium(I) acetate 1
                  tris acetate 0
                  zinc acetate 156
Path 2
Term Annotations click to browse term
  CHEBI ontology 19792
    subatomic particle 19788
      composite particle 19788
        hadron 19788
          baryon 19788
            nucleon 19788
              atomic nucleus 19788
                atom 19788
                  group 19698
                    polyatomic entity 19697
                      heteroatomic molecular entity 19617
                        salt 14624
                          organic salt 2359
                            acetate salt 174
                              (2S)-2-Ethylhexyl acetate 0
                              1-dodecylguanidine acetate 0
                              L-arginyl-L-glutamic acid monoacetate 0
                              ammonium acetate 13
                              caspofungin acetate 0
                              ceftaroline fosamil acetate + 0
                              cetrorelix acetate 0
                              cobalt(II) acetate 1
                              desmopressin acetate (anhydrous) + 0
                              flecainide acetate 0
                              histrelin acetate 0
                              icatibant acetate 0
                              lead tetraacetate 6
                              leuprolide acetate 0
                              lithium acetate 0
                              peginesatide acetate 0
                              praseodymium acetate 0
                              saxitoxin acetate 0
                              thallium(I) acetate 1
                              tris acetate 0
                              zinc acetate 156
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.