Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:thiosalicylic acid
go back to main search page
Accession:CHEBI:59124 term browser browse the term
Definition:A sulfanylbenzoic acid that is the 2-sulfanyl derivative of benzoic acid.
Synonyms:related_synonym: 2-Carboxythiophenol;   2-Mercaptobenzoic acid;   2-Sulfanylbenzoic acid;   2-Thiosalicylic acid;   Formula=C7H6O2S;   InChI=1S/C7H6O2S/c8-7(9)5-3-1-2-4-6(5)10/h1-4,10H,(H,8,9);   InChIKey=NBOMNTLFRHMDEZ-UHFFFAOYSA-N;   SMILES=OC(=O)c1ccccc1S;   Thiophenol-2-carboxylic acid;   o-Benzoic acid thiol;   o-Carboxythiophenol;   o-Mercaptobenzoesaeure;   o-Mercaptobenzoic acid;   o-Sulfhydrylbenzoic acid;   o-Thiosalicylic acid
 xref: Beilstein:508507;   CAS:147-93-3;   Drug_Central:4856;   Gmelin:3838;   KEGG:D08586
 xref_mesh: MESH:C441201
 xref: PDBeChem:JKE;   PMID:1650428;   PMID:23934301;   PMID:24369647;   PMID:24728505;   Patent:DE189200;   Patent:DE205450;   Reaxys:508507;   Wikipedia:Thiosalicylic_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:59127


show annotations for term's descendants           Sort by:
thiosalicylic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions EXP [Diethylnitrosamine co-treated with thiosalicylic acid] results in increased activity of CASP3 protein CTD PMID:19427195 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp8 caspase 8 multiple interactions EXP [Diethylnitrosamine co-treated with thiosalicylic acid] results in increased activity of CASP8 protein CTD PMID:19427195 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Fas Fas cell surface death receptor multiple interactions EXP [Diethylnitrosamine co-treated with thiosalicylic acid] results in increased expression of FAS mRNA; [Diethylnitrosamine co-treated with thiosalicylic acid] results in increased expression of FAS protein CTD PMID:19427195 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Faslg Fas ligand multiple interactions EXP thiosalicylic acid inhibits the reaction [Diethylnitrosamine results in decreased expression of FASL mRNA] CTD PMID:19427195 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Mt1 metallothionein 1 decreases expression ISO thiosalicylic acid results in decreased expression of MT1 mRNA CTD PMID:19386279 NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19932
    role 19904
      biological role 19902
        pharmacological role 19120
          analgesic 14787
            non-narcotic analgesic 13947
              thiosalicylic acid 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19932
    subatomic particle 19930
      composite particle 19930
        hadron 19930
          baryon 19930
            nucleon 19930
              atomic nucleus 19930
                atom 19930
                  main group element atom 19876
                    p-block element atom 19876
                      carbon group element atom 19816
                        carbon atom 19812
                          organic molecular entity 19812
                            heteroorganic entity 19559
                              organochalcogen compound 19317
                                organooxygen compound 19231
                                  carbon oxoacid 18687
                                    carboxylic acid 18684
                                      aromatic carboxylic acid 12708
                                        benzoic acids 12685
                                          sulfanylbenzoic acid 5
                                            thiosalicylic acid 5
paths to the root