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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:thiosalicylic acid
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Accession:CHEBI:59124 term browser browse the term
Definition:A sulfanylbenzoic acid that is the 2-sulfanyl derivative of benzoic acid.
Synonyms:related_synonym: 2-Carboxythiophenol;   2-Mercaptobenzoic acid;   2-Sulfanylbenzoic acid;   2-Thiosalicylic acid;   Formula=C7H6O2S;   InChI=1S/C7H6O2S/c8-7(9)5-3-1-2-4-6(5)10/h1-4,10H,(H,8,9);   InChIKey=NBOMNTLFRHMDEZ-UHFFFAOYSA-N;   SMILES=OC(=O)c1ccccc1S;   Thiophenol-2-carboxylic acid;   o-Benzoic acid thiol;   o-Carboxythiophenol;   o-Mercaptobenzoesaeure;   o-Mercaptobenzoic acid;   o-Sulfhydrylbenzoic acid;   o-Thiosalicylic acid
 xref: Beilstein:508507;   CAS:147-93-3;   Drug_Central:4856;   Gmelin:3838;   KEGG:D08586
 xref_mesh: MESH:C441201
 xref: PDBeChem:JKE;   PMID:1650428;   PMID:23934301;   PMID:24369647;   PMID:24728505;   Patent:DE189200;   Patent:DE205450;   Reaxys:508507;   Wikipedia:Thiosalicylic_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:59127


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thiosalicylic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions EXP [Diethylnitrosamine co-treated with thiosalicylic acid] results in increased activity of CASP3 protein CTD PMID:19427195 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp8 caspase 8 multiple interactions EXP [Diethylnitrosamine co-treated with thiosalicylic acid] results in increased activity of CASP8 protein CTD PMID:19427195 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Fas Fas cell surface death receptor multiple interactions EXP [Diethylnitrosamine co-treated with thiosalicylic acid] results in increased expression of FAS mRNA; [Diethylnitrosamine co-treated with thiosalicylic acid] results in increased expression of FAS protein CTD PMID:19427195 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Faslg Fas ligand multiple interactions EXP thiosalicylic acid inhibits the reaction [Diethylnitrosamine results in decreased expression of FASL mRNA] CTD PMID:19427195 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19811
    role 19818
      biological role 19785
        pharmacological role 19030
          analgesic 14719
            non-narcotic analgesic 13886
              thiosalicylic acid 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19811
    subatomic particle 19809
      composite particle 19809
        hadron 19840
          baryon 19809
            nucleon 19809
              atomic nucleus 19809
                atom 19809
                  main group element atom 19759
                    p-block element atom 19759
                      carbon group element atom 19708
                        carbon atom 19734
                          organic molecular entity 19705
                            heteroorganic entity 19459
                              organochalcogen compound 19222
                                organooxygen compound 19137
                                  carbon oxoacid 18597
                                    carboxylic acid 18594
                                      aromatic carboxylic acid 12571
                                        benzoic acids 12570
                                          sulfanylbenzoic acid 4
                                            thiosalicylic acid 4
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