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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:clopenthixol
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Accession:CHEBI:59115 term browser browse the term
Definition:A thioxanthene derivative having a chloro substituent at the 2-position and an alkylidene group at the 10-position with undefined double bond stereochemistry.
Synonyms:exact_synonym: 2-{4-[3-(2-chloro-9H-thioxanthen-9-ylidene)propyl]piperazin-1-yl}ethan-1-ol
 related_synonym: 2-{4-[3-(2-chloro-10H-dibenzo[b,e]thiopyran-10-ylidene)propyl]piperazin-1-yl}ethanol;   4-(3-(2-Chloro-9H-thioxanthen-9-ylidene)propyl)-1-piperazineethanol;   4-(3-(2-Chlorothioxanthen-9-ylidene)propyl)-1-piperazineethanol;   Chlorpenthixol;   Formula=C22H25ClN2OS;   InChI=1S/C22H25ClN2OS/c23-17-7-8-22-20(16-17)18(19-4-1-2-6-21(19)27-22)5-3-9-24-10-12-25(13-11-24)14-15-26/h1-2,4-8,16,26H,3,9-15H2;   InChIKey=WFPIAZLQTJBIFN-UHFFFAOYSA-N;   SMILES=[H]C(CCN1CCN(CCO)CC1)=C1c2ccccc2Sc2ccc(Cl)cc12;   clopenthixolum;   clopentixol
 xref: Beilstein:899403;   CAS:982-24-1;   Drug_Central:4397;   KEGG:D02613;   LINCS:LSM-2631
 xref_mesh: MESH:D003006
 xref: PMID:1650428;   Patent:BE585338;   Patent:US3116291;   Wikipedia:Clopenthixol


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clopenthixol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Clopenthixol results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
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  CHEBI ontology 19810
    role 19758
      biological role 19758
        pharmacological role 18821
          antagonist 16219
            histamine antagonist 4606
              H1-receptor antagonist 4102
                clopenthixol 1
                  zuclopenthixol 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    main group molecular entity 19696
                      s-block molecular entity 19456
                        hydrogen molecular entity 19447
                          hydrides 18703
                            inorganic hydride 17433
                              pnictogen hydride 17405
                                nitrogen hydride 17247
                                  azane 16964
                                    ammonia 16963
                                      organic amino compound 16962
                                        tertiary amino compound 8638
                                          N-alkylpiperazine 3080
                                            clopenthixol 1
                                              zuclopenthixol 0
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