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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:clopenthixol
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Accession:CHEBI:59115 term browser browse the term
Definition:A thioxanthene derivative having a chloro substituent at the 2-position and an alkylidene group at the 10-position with undefined double bond stereochemistry.
Synonyms:exact_synonym: 2-{4-[3-(2-chloro-9H-thioxanthen-9-ylidene)propyl]piperazin-1-yl}ethan-1-ol
 related_synonym: 2-{4-[3-(2-chloro-10H-dibenzo[b,e]thiopyran-10-ylidene)propyl]piperazin-1-yl}ethanol;   4-(3-(2-Chloro-9H-thioxanthen-9-ylidene)propyl)-1-piperazineethanol;   4-(3-(2-Chlorothioxanthen-9-ylidene)propyl)-1-piperazineethanol;   Chlorpenthixol;   Formula=C22H25ClN2OS;   InChI=1S/C22H25ClN2OS/c23-17-7-8-22-20(16-17)18(19-4-1-2-6-21(19)27-22)5-3-9-24-10-12-25(13-11-24)14-15-26/h1-2,4-8,16,26H,3,9-15H2;   InChIKey=WFPIAZLQTJBIFN-UHFFFAOYSA-N;   SMILES=[H]C(CCN1CCN(CCO)CC1)=C1c2ccccc2Sc2ccc(Cl)cc12;   clopenthixolum;   clopentixol
 xref: Beilstein:899403;   CAS:982-24-1;   Drug_Central:4397;   KEGG:D02613;   LINCS:LSM-2631
 xref_mesh: MESH:D003006
 xref: PMID:1650428;   Patent:BE585338;   Patent:US3116291;   Wikipedia:Clopenthixol


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clopenthixol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Clopenthixol results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19900
    role 19875
      biological role 19873
        pharmacological role 19093
          antagonist 17164
            dopaminergic antagonist 1628
              clopenthixol 1
                zuclopenthixol 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19900
    subatomic particle 19898
      composite particle 19898
        hadron 19898
          baryon 19898
            nucleon 19898
              atomic nucleus 19898
                atom 19898
                  main group element atom 19845
                    main group molecular entity 19845
                      s-block molecular entity 19678
                        hydrogen molecular entity 19667
                          hydrides 19146
                            inorganic hydride 18124
                              pnictogen hydride 18112
                                nitrogen hydride 18017
                                  azane 17816
                                    ammonia 17815
                                      organic amino compound 17815
                                        tertiary amino compound 10133
                                          N-alkylpiperazine 3381
                                            clopenthixol 1
                                              zuclopenthixol 0
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