|
G |
Adipoq |
adiponectin, C1Q and collagen domain containing |
increases expression |
EXP |
Carnitine results in increased expression of ADIPOQ protein |
CTD |
PMID:30256492 |
|
NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
|
|
G |
Akt1 |
AKT serine/threonine kinase 1 |
multiple interactions increases phosphorylation |
EXP |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Carnitine results in increased phosphorylation of AKT1 protein] |
CTD |
PMID:29186614 |
|
NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
|
|
G |
Bax |
BCL2 associated X, apoptosis regulator |
decreases expression multiple interactions |
EXP |
Carnitine results in decreased expression of BAX protein 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Carnitine results in decreased expression of BAX protein] |
CTD |
PMID:29186614 |
|
NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
|
|
G |
Bbox1 |
gamma-butyrobetaine hydroxylase 1 |
multiple interactions increases chemical synthesis |
ISO |
Aluminum inhibits the reaction [BBOX1 protein results in increased chemical synthesis of Carnitine]; Hydrogen Peroxide inhibits the reaction [BBOX1 protein results in increased chemical synthesis of Carnitine]; Ketoglutaric Acids inhibits the reaction [Aluminum inhibits the reaction [BBOX1 protein results in increased chemical synthesis of Carnitine]]; Ketoglutaric Acids inhibits the reaction [Hydrogen Peroxide inhibits the reaction [BBOX1 protein results in increased chemical synthesis of Carnitine]] |
CTD |
PMID:21439360 |
|
NCBI chr 3:101,425,684...101,474,848
Ensembl chr 3:101,427,055...101,474,890
|
|
G |
Bcl2 |
BCL2, apoptosis regulator |
multiple interactions increases phosphorylation |
EXP |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Carnitine results in increased phosphorylation of BCL2 protein]; Carnitine inhibits the reaction [Ifosfamide results in decreased expression of BCL2 mRNA] |
CTD |
PMID:23213347 PMID:29186614 |
|
NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
|
|
G |
Bcl2l1 |
Bcl2-like 1 |
multiple interactions |
EXP |
Carnitine inhibits the reaction [Gentamicins results in decreased expression of BCL2L1 protein] |
CTD |
PMID:19491382 |
|
NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
|
|
G |
Casp3 |
caspase 3 |
multiple interactions |
EXP |
Carnitine inhibits the reaction [Gentamicins results in increased cleavage of CASP3 protein]; Carnitine inhibits the reaction [Ifosfamide results in increased expression of CASP3 mRNA]; Carnitine inhibits the reaction [Iohexol promotes the reaction [Glycerol results in increased expression of CASP3 mRNA]] |
CTD |
PMID:19491382 PMID:23213347 PMID:26562095 |
|
NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
|
|
G |
Casp9 |
caspase 9 |
multiple interactions |
EXP |
Carnitine inhibits the reaction [Ifosfamide results in increased expression of CASP9 mRNA] |
CTD |
PMID:23213347 |
|
NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
|
|
G |
Cat |
catalase |
multiple interactions |
EXP |
Carnitine inhibits the reaction [Diethylnitrosamine results in decreased activity of CAT protein]; Carnitine inhibits the reaction [Doxorubicin results in decreased activity of CAT protein]; Carnitine inhibits the reaction [Ifosfamide results in decreased expression of CAT mRNA] |
CTD |
PMID:16889571 PMID:19294768 PMID:23213347 |
|
NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
|
|
G |
Ccn2 |
cellular communication network factor 2 |
multiple interactions |
EXP |
Carnitine inhibits the reaction [Sunitinib results in increased expression of CCN2 mRNA] |
CTD |
PMID:26581635 |
|
NCBI chr 1:21,851,657...21,854,773
Ensembl chr 1:21,851,660...21,854,773
|
|
G |
Cdh1 |
cadherin 1 |
multiple interactions |
EXP |
Carnitine inhibits the reaction [perfluorooctane sulfonic acid results in decreased expression of CDH1 protein] |
CTD |
PMID:28973641 |
|
NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
|
|
G |
Col1a1 |
collagen type I alpha 1 chain |
multiple interactions |
EXP |
Carnitine inhibits the reaction [perfluorooctane sulfonic acid results in increased expression of COL1A1 mRNA]; Carnitine inhibits the reaction [Sunitinib results in increased expression of COL1A1 mRNA] |
CTD |
PMID:26581635 PMID:28973641 |
|
NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
|
|
G |
Col2a1 |
collagen type II alpha 1 chain |
multiple interactions |
EXP |
[COL2A1 protein co-treated with Freund's Adjuvant] affects the abundance of Carnitine; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Carnitine]; Dexamethasone inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Carnitine]; huang-lien-chieh-tu-tang inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Carnitine] |
CTD |
PMID:24709313 |
|
NCBI chr 7:139,454,945...139,484,403
Ensembl chr 7:139,455,242...139,483,997
|
|
G |
Cpt1a |
carnitine palmitoyltransferase 1A |
multiple interactions |
EXP ISO |
valproyl-coenzyme A inhibits the reaction [CPT1A protein results in increased metabolism of Carnitine] [Doxorubicin co-treated with Carnitine] results in increased expression of CPT1A mRNA; [Genistein co-treated with Carnitine] results in increased expression of CPT1A protein |
CTD |
PMID:16283381 PMID:16362726 PMID:19854160 |
|
NCBI chr 1:218,568,157...218,629,679
Ensembl chr 1:218,569,510...218,629,678
|
|
G |
Cpt2 |
carnitine palmitoyltransferase 2 |
multiple interactions |
ISO |
Carnitine promotes the reaction [[Bezafibrate results in increased activity of CPT2 protein] which results in increased abundance of Adenosine Triphosphate] |
CTD |
PMID:21816645 |
|
NCBI chr 5:127,505,646...127,523,016
Ensembl chr 5:127,505,614...127,523,089
|
|
G |
Cybb |
cytochrome b-245 beta chain |
multiple interactions |
EXP |
Carnitine inhibits the reaction [sunitinib results in increased expression of NOX2 mRNA]; Carnitine inhibits the reaction [sunitinib results in increased expression of NOX2 protein] |
CTD |
PMID:26581635 |
|
NCBI chr X:14,578,330...14,610,049
Ensembl chr X:14,578,264...14,612,547
|
|
G |
Cyp17a1 |
cytochrome P450, family 17, subfamily a, polypeptide 1 |
multiple interactions |
EXP |
Carnitine inhibits the reaction [Atrazine results in decreased expression of CYP17A1 mRNA] |
CTD |
PMID:29710542 |
|
NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239
|
|
G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
multiple interactions |
EXP |
Carnitine promotes the reaction [Ethanol results in increased expression of CYP2E1 protein] |
CTD |
PMID:8130774 |
|
NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
|
|
G |
Fabp3 |
fatty acid binding protein 3 |
multiple interactions |
EXP |
Carnitine inhibits the reaction [Doxorubicin results in decreased expression of FABP3 mRNA] |
CTD |
PMID:20470772 |
|
NCBI chr 5:148,528,854...148,535,597
Ensembl chr 5:148,528,725...148,535,565
|
|
G |
Gpx1 |
glutathione peroxidase 1 |
multiple interactions |
EXP |
Carnitine inhibits the reaction [Ifosfamide results in decreased expression of GPX1 mRNA] |
CTD |
PMID:23213347 |
|
NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
|
|
G |
Hrk |
harakiri, BCL2 interacting protein |
multiple interactions |
ISO |
Carnitine inhibits the reaction [Gentamicins results in increased expression of HRK mRNA]; Carnitine inhibits the reaction [Gentamicins results in increased expression of HRK protein] |
CTD |
PMID:16239342 |
|
NCBI chr12:44,008,879...44,029,211
|
|
G |
Hspa2 |
heat shock protein family A (Hsp70) member 2 |
multiple interactions |
EXP |
Carnitine inhibits the reaction [Cadmium Chloride results in increased expression of HSPA2 protein] |
CTD |
PMID:22359436 |
|
NCBI chr 6:99,433,575...99,436,288
Ensembl chr 6:99,433,550...99,436,289
|
|
G |
Idh2 |
isocitrate dehydrogenase (NADP(+)) 2 |
multiple interactions increases abundance |
ISO |
Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of Carnitine] |
CTD |
PMID:27469509 |
|
NCBI chr 1:141,874,354...141,893,674
Ensembl chr 1:141,866,283...141,893,705
|
|
G |
Il10 |
interleukin 10 |
multiple interactions |
EXP |
Carnitine inhibits the reaction [sunitinib results in decreased expression of IL10 mRNA] |
CTD |
PMID:26581635 |
|
NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
|
|
G |
Il1b |
interleukin 1 beta |
multiple interactions |
EXP |
Carnitine inhibits the reaction [Iohexol promotes the reaction [Glycerol results in increased expression of IL1B mRNA]]; Carnitine inhibits the reaction [sunitinib results in increased expression of IL1B mRNA] |
CTD |
PMID:26562095 PMID:26581635 |
|
NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
|
|
G |
Il6 |
interleukin 6 |
multiple interactions |
EXP |
Carnitine inhibits the reaction [sunitinib results in increased expression of IL6 mRNA] |
CTD |
PMID:26581635 |
|
NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
|
|
G |
Lepr |
leptin receptor |
affects abundance |
ISO |
LEPR affects the abundance of Carnitine |
CTD |
PMID:20567778 |
|
NCBI chr 5:120,503,475...120,682,281
Ensembl chr 5:120,564,645...120,682,221
|
|
G |
Mmp9 |
matrix metallopeptidase 9 |
multiple interactions |
EXP |
Carnitine inhibits the reaction [sunitinib results in decreased expression of MMP9 mRNA] |
CTD |
PMID:26581635 |
|
NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
|
|
G |
Mpo |
myeloperoxidase |
multiple interactions increases activity |
EXP |
[Carboplatin co-treated with Carnitine deficiency] results in increased expression of MPO protein; Acetaminophen promotes the reaction [Carnitine deficiency results in increased activity of MPO protein] |
CTD |
PMID:18597074 PMID:18852009 |
|
NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
|
|
G |
Mt-co1 |
mitochondrially encoded cytochrome c oxidase I |
multiple interactions |
ISO |
Carnitine inhibits the reaction [nickel chloride results in decreased expression of COX1 mRNA] |
CTD |
PMID:21419151 |
|
NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867
|
|
G |
Mt-nd6 |
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 |
multiple interactions |
ISO |
Carnitine inhibits the reaction [nickel chloride results in decreased expression of ND6 mRNA] |
CTD |
PMID:21419151 |
|
NCBI chr MT:13,543...14,061
Ensembl chr MT:13,543...14,061
|
|
G |
Mttp |
microsomal triglyceride transfer protein |
multiple interactions |
EXP |
Carnitine inhibits the reaction [Stavudine results in decreased expression of MTTP mRNA] |
CTD |
PMID:18299183 |
|
NCBI chr 2:243,366,181...243,407,608
Ensembl chr 2:243,366,181...243,407,608
|
|
G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions |
EXP |
Carnitine inhibits the reaction [Ifosfamide results in increased expression of NOS2 mRNA] |
CTD |
PMID:23213347 |
|
NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
|
|
G |
Nos3 |
nitric oxide synthase 3 |
increases expression |
EXP |
Carnitine results in increased expression of NOS3 |
CTD |
PMID:20123095 |
|
NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
|
|
G |
Ppara |
peroxisome proliferator activated receptor alpha |
multiple interactions increases activity |
EXP |
[pirinixic acid results in increased activity of PPARA protein] promotes the reaction [SLC22A21 protein results in increased uptake of Carnitine]; PPARA protein promotes the reaction [Carnitine results in decreased susceptibility to Gentamicins] Carnitine results in increased activity of PPARA protein |
CTD |
PMID:19491382 PMID:19735737 |
|
NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
|
|
G |
Pparg |
peroxisome proliferator-activated receptor gamma |
increases expression multiple interactions |
EXP |
Carnitine results in increased expression of PPARG protein Carnitine inhibits the reaction [[Dietary Fats co-treated with Fructose] results in decreased expression of PPARG protein] |
CTD |
PMID:30256492 |
|
NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
|
|
G |
Ptgis |
prostaglandin I2 synthase |
increases expression increases response to substance multiple interactions |
EXP |
Carnitine results in increased expression of PTGIS mRNA PTGIS protein results in increased susceptibility to Carnitine [Carnitine results in increased expression of PTGIS mRNA] which results in increased chemical synthesis of 6-Ketoprostaglandin F1 alpha |
CTD |
PMID:19491382 |
|
NCBI chr 3:163,950,746...163,986,129
|
|
G |
Slc22a4 |
solute carrier family 22 member 4 |
increases uptake |
ISO |
SLC22A4 protein results in increased uptake of Carnitine |
CTD |
PMID:21256917 |
|
NCBI chr10:39,334,972...39,373,508
|
|
G |
Slc22a5 |
solute carrier family 22 member 5 |
multiple interactions decreases expression increases transport increases uptake increases expression affects uptake affects binding |
ISO EXP |
[Doxorubicin co-treated with Carnitine] results in increased expression of SLC22A5 mRNA; Amiodarone inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine]; Atorvastatin inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine]; Betaine inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine]; Carnitine inhibits the reaction [SLC22A5 protein results in increased transport of pivaloylcarnitine]; Choline inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine]; Clozapine inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine]; grepafloxacin affects the reaction [SLC22A5 protein results in increased uptake of Carnitine]; Ipratropium inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine]; Lidocaine inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine]; Nifedipine inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine]; Ofloxacin inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine]; Olanzapine inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine analog]; pivaloylcarnitine inhibits the reaction [SLC22A5 protein results in increased transport of Carnitine]; Propranolol inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine]; Quetiapine Fumarate inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine]; Spironolactone inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine]; talinolol inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine]; ziprasidone inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine] Carnitine results in decreased expression of SLC22A5 mRNA; Carnitine results in decreased expression of SLC22A5 protein 1-Methyl-4-phenylpyridinium inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine]; Carnitine inhibits the reaction [Cyclophosphamide results in decreased expression of SLC22A5 mRNA]; Carnitine inhibits the reaction [Cyclophosphamide results in decreased expression of SLC22A5 protein]; Carnitine inhibits the reaction [Doxorubicin results in decreased expression of SLC22A5 mRNA]; Carnitine inhibits the reaction [SLC22A5 protein results in increased uptake of Tetraethylammonium]; Dithioerythritol inhibits the reaction [Omeprazole inhibits the reaction [SLC22A5 protein results in increased transport of Carnitine]]; Ofloxacin inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine]; Omeprazole inhibits the reaction [SLC22A5 protein results in increased transport of Carnitine]; Tetraethylammonium inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine] Carnitine deficiency results in increased expression of SLC22A5 mRNA SLC22A5 protein results in increased uptake of Carnitine; SLC22A5 protein results in increased uptake of Carnitine analog SLC22A5 protein affects the uptake of Carnitine Carnitine binds to SLC22A5 protein |
CTD |
PMID:12644265 PMID:15486076 PMID:16283381 PMID:16928358 PMID:18762717 PMID:18981167 PMID:19041296 PMID:19539806 PMID:19735737 PMID:20303936 PMID:20470772 PMID:21256917 PMID:21641380 PMID:22701146 PMID:30465787 PMID:31437515 |
|
NCBI chr10:39,201,101...39,228,090
Ensembl chr10:39,201,107...39,323,853
|
|
G |
Slc22a8 |
solute carrier family 22 member 8 |
increases transport |
ISO |
SLC22A8 protein results in increased transport of Carnitine |
CTD |
PMID:15100168 |
|
NCBI chr 1:224,799,444...224,818,482
Ensembl chr 1:224,800,252...224,818,482
|
|
G |
Slc25a20 |
solute carrier family 25 member 20 |
multiple interactions increases transport |
EXP |
Ampicillin inhibits the reaction [SLC25A20 protein results in increased transport of Carnitine]; Carnitine inhibits the reaction [Hydrogen Peroxide results in decreased activity of SLC25A20 protein]; Cefazolin inhibits the reaction [SLC25A20 protein results in increased transport of Carnitine]; Cefonicid inhibits the reaction [SLC25A20 protein results in increased transport of Carnitine]; Cephalothin inhibits the reaction [SLC25A20 protein results in increased transport of Carnitine]; Piperacillin inhibits the reaction [SLC25A20 protein results in increased transport of Carnitine] |
CTD |
PMID:18452908 PMID:23402788 |
|
NCBI chr 8:117,455,308...117,476,762
Ensembl chr 8:117,455,262...117,476,734
|
|
G |
Slc2a4 |
solute carrier family 2 member 4 |
increases expression multiple interactions |
EXP |
Carnitine results in increased expression of SLC2A4 protein Carnitine inhibits the reaction [[Dietary Fats co-treated with Fructose] results in decreased expression of SLC2A4 protein] |
CTD |
PMID:30256492 |
|
NCBI chr10:56,552,921...56,558,562
Ensembl chr10:56,552,983...56,558,487
|
|
G |
Snai1 |
snail family transcriptional repressor 1 |
multiple interactions |
EXP |
Carnitine inhibits the reaction [perfluorooctane sulfonic acid results in increased expression of SNAI1 protein] |
CTD |
PMID:28973641 |
|
NCBI chr 3:164,274,710...164,279,199
Ensembl chr 3:164,274,710...164,279,378
|
|
G |
Srebf1 |
sterol regulatory element binding transcription factor 1 |
multiple interactions |
EXP |
Carnitine inhibits the reaction [Stavudine results in increased expression of SREBF1 mRNA] |
CTD |
PMID:18299183 |
|
NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009
|
|
G |
Tgfb1 |
transforming growth factor, beta 1 |
multiple interactions |
EXP |
Carnitine inhibits the reaction [Iohexol promotes the reaction [Glycerol results in increased expression of TGFB1 mRNA]]; Carnitine inhibits the reaction [perfluorooctane sulfonic acid results in increased expression of TGFB1 mRNA]; Carnitine inhibits the reaction [sunitinib results in increased expression of TGFB1 mRNA] |
CTD |
PMID:26562095 PMID:26581635 PMID:28973641 |
|
NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
|
|
G |
Timp1 |
TIMP metallopeptidase inhibitor 1 |
multiple interactions |
EXP |
Carnitine inhibits the reaction [sunitinib results in increased expression of TIMP1 mRNA] |
CTD |
PMID:26581635 |
|
NCBI chr X:1,364,771...1,369,451
Ensembl chr X:1,364,786...1,369,384
|
|
G |
Tjp1 |
tight junction protein 1 |
multiple interactions |
EXP |
Carnitine inhibits the reaction [perfluorooctane sulfonic acid results in decreased expression of TJP1 protein] |
CTD |
PMID:28973641 |
|
NCBI chr 1:126,146,489...126,515,359
Ensembl chr 1:126,146,489...126,227,469
|
|
G |
Tnf |
tumor necrosis factor |
increases expression multiple interactions decreases expression |
EXP |
Carnitine deficiency results in increased expression of TNF mRNA [Carboplatin co-treated with Carnitine deficiency] results in increased expression of TNF protein; Acetaminophen promotes the reaction [Carnitine deficiency results in increased expression of TNF mRNA]; Carnitine inhibits the reaction [Iohexol promotes the reaction [Glycerol results in increased expression of TNF mRNA]]; Carnitine inhibits the reaction [Iohexol promotes the reaction [Glycerol results in increased expression of TNF protein]] Carnitine results in decreased expression of TNF protein |
CTD |
PMID:18597074 PMID:18629605 PMID:18852009 PMID:26562095 |
|
NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
|
|
G |
Vim |
vimentin |
multiple interactions |
EXP |
Carnitine inhibits the reaction [perfluorooctane sulfonic acid results in increased expression of VIM protein] |
CTD |
PMID:28973641 |
|
NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212
|
|
|
G |
Bbox1 |
gamma-butyrobetaine hydroxylase 1 |
multiple interactions |
ISO |
[BBOX1 protein co-treated with Ketoglutaric Acids] results in increased metabolism of gamma-butyrobetaine |
CTD |
PMID:21439360 |
|
NCBI chr 3:101,425,684...101,474,848
Ensembl chr 3:101,427,055...101,474,890
|
|
G |
Idh2 |
isocitrate dehydrogenase (NADP(+)) 2 |
multiple interactions increases abundance |
ISO |
Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of gamma-butyrobetaine] |
CTD |
PMID:27469509 |
|
NCBI chr 1:141,874,354...141,893,674
Ensembl chr 1:141,866,283...141,893,705
|
|
|
G |
A2m |
alpha-2-macroglobulin |
decreases expression |
ISO |
Aminocaproic Acid results in decreased expression of A2M protein |
CTD |
PMID:11304663 |
|
NCBI chr 4:154,309,426...154,359,138
Ensembl chr 4:154,309,426...154,359,137
|
|
G |
Folh1 |
folate hydrolase 1 |
multiple interactions |
ISO |
[2-(3-(1,3-dicarboxypropyl)ureido)pentanedioic acid binds to Aminocaproic Acid binds to 1-(1,3-carboxypropyl)-4,7-carboxymethyl-1,4,7-triazacyclononane binds to Valerates binds to bombesin (7-14) binds to Copper] inhibits the reaction [isospaglumic acid binds to FOLH1 protein] |
CTD |
PMID:24508213 |
|
NCBI chr 1:150,323,768...150,395,415
Ensembl chr 1:150,323,768...150,395,415
|
|
G |
Grpr |
gastrin releasing peptide receptor |
multiple interactions |
ISO |
[2-(3-(1,3-dicarboxypropyl)ureido)pentanedioic acid binds to Aminocaproic Acid binds to 1-(1,3-carboxypropyl)-4,7-carboxymethyl-1,4,7-triazacyclononane binds to Valerates binds to bombesin (7-14) binds to Copper] inhibits the reaction [bombesin, Tyr(4)- binds to GRPR protein] |
CTD |
PMID:24508213 |
|
NCBI chr X:32,746,259...32,786,266
Ensembl chr X:32,745,873...32,786,359
|
|
G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions |
ISO |
Aminocaproic Acid inhibits the reaction [PLG protein results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:17482686 |
|
NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
|
|
G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions |
ISO |
Aminocaproic Acid inhibits the reaction [PLG protein results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:17482686 |
|
NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
|
|
G |
Plg |
plasminogen |
multiple interactions |
ISO |
Aminocaproic Acid inhibits the reaction [PLG protein results in increased phosphorylation of MAPK1 protein]; Aminocaproic Acid inhibits the reaction [PLG protein results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:17482686 |
|
NCBI chr 1:48,521,828...48,563,895
Ensembl chr 1:48,521,772...48,563,776
|
|
G |
Serpinc1 |
serpin family C member 1 |
increases expression |
ISO |
Aminocaproic Acid results in increased expression of SERPINC1 protein |
CTD |
PMID:11304663 |
|
NCBI chr13:78,806,107...78,820,375
Ensembl chr13:78,805,347...78,833,192
|
|
|
G |
Slc22a5 |
solute carrier family 22 member 5 |
affects binding increases uptake multiple interactions increases transport |
ISO EXP |
pivaloylcarnitine binds to SLC22A5 protein SLC22A5 protein results in increased uptake of pivaloylcarnitine Carnitine inhibits the reaction [SLC22A5 protein results in increased transport of pivaloylcarnitine]; pivaloylcarnitine inhibits the reaction [SLC22A5 protein results in increased transport of Carnitine] |
CTD |
PMID:18762717 PMID:19539806 |
|
NCBI chr10:39,201,101...39,228,090
Ensembl chr10:39,201,107...39,323,853
|
|
|
G |
Ache |
acetylcholinesterase |
multiple interactions |
EXP |
Acetylcarnitine inhibits the reaction [Dexamethasone results in decreased activity of ACHE protein]; Acetylcarnitine inhibits the reaction [Dexamethasone results in increased activity of ACHE protein] |
CTD |
PMID:21986892 |
|
NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
|
|
G |
Apex1 |
apurinic/apyrimidinic endodeoxyribonuclease 1 |
increases expression |
EXP |
Acetylcarnitine results in increased expression of APEX1 mRNA |
CTD |
PMID:14654561 |
|
NCBI chr15:27,849,943...27,852,083
Ensembl chr15:27,849,979...27,852,082
|
|
G |
Atp6v1f |
ATPase H+ transporting V1 subunit F |
increases expression |
EXP |
Acetylcarnitine results in increased expression of ATP6V1F mRNA |
CTD |
PMID:14654561 |
|
NCBI chr 4:56,744,563...56,747,657
Ensembl chr 4:56,744,561...56,747,656
|
|
G |
C1qa |
complement C1q A chain |
decreases expression |
ISO |
Acetylcarnitine results in decreased expression of C1QA mRNA |
CTD |
PMID:19555370 |
|
NCBI chr 5:155,261,254...155,264,101
Ensembl chr 5:155,261,250...155,264,143
|
|
G |
C4b |
complement C4B (Chido blood group) |
decreases expression |
ISO |
Acetylcarnitine results in decreased expression of C4B mRNA |
CTD |
PMID:19555370 |
|
NCBI chr20:4,302,344...4,316,752
Ensembl chr20:4,302,344...4,316,715
|
|
G |
Casp3 |
caspase 3 |
multiple interactions |
EXP |
Acetylcarnitine inhibits the reaction [sodium arsenite results in increased activity of CASP3 protein]; Acetylcarnitine inhibits the reaction [Sodium Selenite results in increased expression of CASP3 mRNA] |
CTD |
PMID:20067779 PMID:29278859 |
|
NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
|
|
G |
Casp9 |
caspase 9 |
multiple interactions |
EXP |
Acetylcarnitine inhibits the reaction [sodium arsenite results in increased activity of CASP9 protein] |
CTD |
PMID:29278859 |
|
NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
|
|
G |
Cat |
catalase |
multiple interactions |
EXP |
Acetylcarnitine inhibits the reaction [sodium arsenite results in decreased activity of CAT protein]; Acetylcarnitine inhibits the reaction [Sodium Selenite results in decreased expression of CAT mRNA] |
CTD |
PMID:20067779 PMID:26349760 PMID:29278859 |
|
NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
|
|
G |
Col2a1 |
collagen type II alpha 1 chain |
multiple interactions |
EXP |
[COL2A1 protein co-treated with Freund's Adjuvant] results in decreased abundance of Acetylcarnitine |
CTD |
PMID:24709313 |
|
NCBI chr 7:139,454,945...139,484,403
Ensembl chr 7:139,455,242...139,483,997
|
|
G |
Ctss |
cathepsin S |
decreases expression |
ISO |
Acetylcarnitine results in decreased expression of CTSS mRNA |
CTD |
PMID:19555370 |
|
NCBI chr 2:197,655,780...197,679,768
Ensembl chr 2:197,655,786...197,679,458
|
|
G |
Cxcl14 |
C-X-C motif chemokine ligand 14 |
decreases expression |
ISO |
Acetylcarnitine results in decreased expression of CXCL14 mRNA |
CTD |
PMID:19555370 |
|
NCBI chr17:9,109,731...9,117,754
Ensembl chr17:9,109,731...9,117,750
|
|
G |
Egr1 |
early growth response 1 |
multiple interactions |
EXP |
Acetylcarnitine inhibits the reaction [Sodium Selenite results in increased expression of EGR1 mRNA] |
CTD |
PMID:20067779 |
|
NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
|
|
G |
Gfap |
glial fibrillary acidic protein |
decreases expression |
ISO |
Acetylcarnitine results in decreased expression of GFAP mRNA |
CTD |
PMID:19555370 |
|
NCBI chr10:90,990,762...90,999,435
Ensembl chr10:90,990,762...90,999,506
|
|
G |
Gsr |
glutathione-disulfide reductase |
multiple interactions |
ISO |
Acetylcarnitine inhibits the reaction [Acetaminophen results in decreased expression of GSR protein] |
CTD |
PMID:26265018 |
|
NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
|
|
G |
Gstp1 |
glutathione S-transferase pi 1 |
multiple interactions |
EXP |
Acetylcarnitine affects the reaction [Dexamethasone results in decreased expression of GSTP1 mRNA] |
CTD |
PMID:21986892 |
|
NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
|
|
G |
Hmox1 |
heme oxygenase 1 |
multiple interactions |
EXP |
Acetylcarnitine affects the reaction [Dexamethasone results in increased expression of HMOX1 mRNA] |
CTD |
PMID:21986892 |
|
NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
|
|
G |
Hmox2 |
heme oxygenase 2 |
multiple interactions |
EXP |
Acetylcarnitine affects the reaction [Dexamethasone results in increased expression of HMOX2 mRNA] |
CTD |
PMID:21986892 |
|
NCBI chr10:10,990,034...11,035,493
Ensembl chr10:10,990,034...11,035,484
|
|
G |
Hspb1 |
heat shock protein family B (small) member 1 |
decreases expression |
EXP |
Acetylcarnitine results in decreased expression of HSPB1 mRNA |
CTD |
PMID:14654561 |
|
NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
|
|
G |
Idh2 |
isocitrate dehydrogenase (NADP(+)) 2 |
increases abundance multiple interactions |
ISO |
IDH2 protein mutant form results in increased abundance of Acetylcarnitine Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of Acetylcarnitine] |
CTD |
PMID:27469509 |
|
NCBI chr 1:141,874,354...141,893,674
Ensembl chr 1:141,866,283...141,893,705
|
|
G |
Il1b |
interleukin 1 beta |
multiple interactions |
EXP |
Acetylcarnitine inhibits the reaction [sodium arsenite results in increased expression of IL1B protein] |
CTD |
PMID:29278859 |
|
NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
|
|
G |
Il6 |
interleukin 6 |
multiple interactions |
EXP |
Acetylcarnitine inhibits the reaction [sodium arsenite results in increased expression of IL6 protein] |
CTD |
PMID:29278859 |
|
NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
|
|
G |
Mgst1 |
microsomal glutathione S-transferase 1 |
increases expression |
EXP |
Acetylcarnitine results in increased expression of MGST1 mRNA |
CTD |
PMID:14654561 |
|
NCBI chr 4:172,119,382...172,134,609
Ensembl chr 4:172,119,331...172,134,607
|
|
G |
Mt-co1 |
mitochondrially encoded cytochrome c oxidase I |
multiple interactions |
EXP |
Acetylcarnitine inhibits the reaction [Sodium Selenite results in decreased expression of COX1 mRNA] |
CTD |
PMID:20067779 |
|
NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867
|
|
G |
Ngf |
nerve growth factor |
multiple interactions |
EXP |
Acetylcarnitine inhibits the reaction [Cisplatin results in decreased expression of NGF protein] |
CTD |
PMID:14654561 |
|
NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453
|
|
G |
Nos1 |
nitric oxide synthase 1 |
multiple interactions |
EXP |
Acetylcarnitine affects the reaction [Dexamethasone results in increased expression of NOS1 mRNA] |
CTD |
PMID:21986892 |
|
NCBI chr12:44,214,949...44,405,530
Ensembl chr12:44,213,943...44,520,341
|
|
G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions |
EXP |
Acetylcarnitine affects the reaction [Dexamethasone results in increased expression of NOS2 mRNA] |
CTD |
PMID:21986892 |
|
NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
|
|
G |
Pah |
phenylalanine hydroxylase |
decreases expression |
ISO |
Acetylcarnitine results in decreased expression of PAH mRNA |
CTD |
PMID:19555370 |
|
NCBI chr 7:28,066,639...28,129,772
Ensembl chr 7:28,066,635...28,129,769
|
|
G |
Pink1 |
PTEN induced kinase 1 |
multiple interactions |
ISO |
Acetylcarnitine inhibits the reaction [Cadmium results in increased expression of PINK1] |
CTD |
PMID:25464205 |
|
NCBI chr 5:156,677,146...156,689,258
Ensembl chr 5:156,677,146...156,689,415
|
|
G |
Ppargc1a |
PPARG coactivator 1 alpha |
increases expression multiple interactions |
ISO |
Acetylcarnitine results in increased expression of PPARGC1A protein [Acetylcarnitine co-treated with Thioctic Acid] results in increased expression of PPARGC1A protein |
CTD |
PMID:20414966 |
|
NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
|
|
G |
Prkn |
parkin RBR E3 ubiquitin protein ligase |
multiple interactions |
ISO |
Acetylcarnitine inhibits the reaction [Cadmium results in increased expression of PRKN] |
CTD |
PMID:25464205 |
|
NCBI chr 1:48,880,015...50,069,998
|
|
G |
Psmb6 |
proteasome 20S subunit beta 6 |
increases expression |
EXP |
Acetylcarnitine results in increased expression of PSMB6 mRNA |
CTD |
PMID:14654561 |
|
NCBI chr10:57,131,339...57,133,685
Ensembl chr10:57,131,386...57,133,637
|
|
G |
Ptma |
prothymosin alpha |
increases expression |
EXP |
Acetylcarnitine results in increased expression of PTMA mRNA |
CTD |
PMID:14654561 |
|
NCBI chr 9:93,545,396...93,549,436
Ensembl chr 9:93,545,396...93,549,436
|
|
G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
EXP |
Acetylcarnitine inhibits the reaction [sodium arsenite results in increased expression of RELA protein] |
CTD |
PMID:29278859 |
|
NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
|
|
G |
Rps17 |
ribosomal protein S17 |
increases expression |
EXP |
Acetylcarnitine results in increased expression of RPS17 mRNA |
CTD |
PMID:14654561 |
|
NCBI chr 1:143,167,329...143,169,915
Ensembl chr 1:143,167,362...143,169,657
|
|
G |
Skap2 |
src kinase associated phosphoprotein 2 |
decreases expression |
ISO |
Acetylcarnitine results in decreased expression of SKAP2 mRNA |
CTD |
PMID:19555370 |
|
NCBI chr 4:81,816,778...81,968,832
Ensembl chr 4:81,818,569...81,968,832
|
|
G |
Slc25a20 |
solute carrier family 25 member 20 |
multiple interactions |
EXP |
Acetylcarnitine inhibits the reaction [Hydrogen Peroxide results in decreased activity of SLC25A20 protein] |
CTD |
PMID:23402788 |
|
NCBI chr 8:117,455,308...117,476,762
Ensembl chr 8:117,455,262...117,476,734
|
|
G |
Snca |
synuclein alpha |
multiple interactions |
ISO |
[Acetylcarnitine co-treated with Thioctic Acid] inhibits the reaction [Rotenone results in increased expression of SNCA protein]; Acetylcarnitine inhibits the reaction [Rotenone results in increased expression of SNCA protein] |
CTD |
PMID:20414966 |
|
NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
|
|
G |
Tnni3 |
troponin I3, cardiac type |
multiple interactions |
EXP |
Acetylcarnitine inhibits the reaction [Cisplatin results in increased expression of TNNI3 protein] |
CTD |
PMID:21034734 |
|
NCBI chr 1:72,882,806...72,886,490
Ensembl chr 1:72,882,806...72,886,488
|
|
|
G |
Idh2 |
isocitrate dehydrogenase (NADP(+)) 2 |
multiple interactions increases abundance |
ISO |
Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of butyrylcarnitine] |
CTD |
PMID:27469509 |
|
NCBI chr 1:141,874,354...141,893,674
Ensembl chr 1:141,866,283...141,893,705
|
|
|
G |
Crot |
carnitine O-octanoyltransferase |
increases chemical synthesis |
ISO |
CROT protein results in increased chemical synthesis of octanoylcarnitine |
CTD |
PMID:6838215 |
|
NCBI chr 4:22,079,837...22,116,265
Ensembl chr 4:22,081,604...22,116,265
|
|
|
G |
Col2a1 |
collagen type II alpha 1 chain |
multiple interactions |
EXP |
[COL2A1 protein co-treated with Freund's Adjuvant] results in decreased abundance of Palmitoylcarnitine |
CTD |
PMID:24709313 |
|
NCBI chr 7:139,454,945...139,484,403
Ensembl chr 7:139,455,242...139,483,997
|
|
G |
Gls |
glutaminase |
increases chemical synthesis |
ISO |
GLS protein results in increased chemical synthesis of Palmitoylcarnitine |
CTD |
PMID:31040181 |
|
NCBI chr 9:54,212,622...54,284,879
Ensembl chr 9:54,212,767...54,284,872
|
|
G |
Ppp3r1 |
protein phosphatase 3, regulatory subunit B, alpha |
decreases metabolic processing |
ISO |
PPP3R1 gene mutant form results in decreased metabolism of Palmitoylcarnitine |
CTD |
PMID:19700627 |
|
NCBI chr14:100,311,224...100,360,879
Ensembl chr14:100,311,173...100,360,879
|
|
G |
Prkaa1 |
protein kinase AMP-activated catalytic subunit alpha 1 |
increases chemical synthesis |
ISO |
PRKAA1 protein results in increased chemical synthesis of Palmitoylcarnitine |
CTD |
PMID:31040181 |
|
NCBI chr 2:54,857,688...54,893,404
Ensembl chr 2:54,857,688...54,893,404
|
|
|
G |
Acox1 |
acyl-CoA oxidase 1 |
increases metabolic processing multiple interactions |
ISO |
ACOX1 protein results in increased metabolism of Palmitoyl Coenzyme A [ACOX1 protein results in increased metabolism of Palmitoyl Coenzyme A] which results in increased chemical synthesis of Hydrogen Peroxide; benz(a)anthracene promotes the reaction [[ACOX1 protein results in increased metabolism of Palmitoyl Coenzyme A] which results in increased chemical synthesis of Hydrogen Peroxide]; Dehydroepiandrosterone promotes the reaction [[ACOX1 protein results in increased metabolism of Palmitoyl Coenzyme A] which results in increased chemical synthesis of Hydrogen Peroxide]; Tetrachlorodibenzodioxin promotes the reaction [[ACOX1 protein results in increased metabolism of Palmitoyl Coenzyme A] which results in increased chemical synthesis of Hydrogen Peroxide] |
CTD |
PMID:10497882 |
|
NCBI chr10:104,724,534...104,748,003
Ensembl chr10:104,722,958...104,748,050
|
|
G |
Ces1d |
carboxylesterase 1D |
increases hydrolysis |
EXP |
CES1 protein results in increased hydrolysis of Palmitoyl Coenzyme A |
CTD |
PMID:8611161 |
|
NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
|
|
G |
Cpt1a |
carnitine palmitoyltransferase 1A |
multiple interactions |
EXP |
valproyl-coenzyme A inhibits the reaction [CPT1A protein results in increased metabolism of Palmitoyl Coenzyme A] |
CTD |
PMID:19854160 |
|
NCBI chr 1:218,568,157...218,629,679
Ensembl chr 1:218,569,510...218,629,678
|
|
G |
Dgat1 |
diacylglycerol O-acyltransferase 1 |
multiple interactions |
ISO |
DGAT1 protein results in increased metabolism of [Palmitoyl Coenzyme A co-treated with Vitamin A] |
CTD |
PMID:16214399 |
|
NCBI chr 7:117,566,363...117,576,735
Ensembl chr 7:117,566,368...117,576,737
|
|
G |
Gsta1 |
glutathione S-transferase alpha 1 |
multiple interactions |
ISO |
Palmitoyl Coenzyme A binds to and results in decreased activity of GSTA1 protein |
CTD |
PMID:10542059 |
|
NCBI chr 9:27,366,404...27,381,004
Ensembl chr 9:27,368,272...27,452,902
|
|
G |
Hnf4a |
hepatocyte nuclear factor 4, alpha |
decreases expression |
ISO |
Palmitoyl Coenzyme A results in decreased expression of HNF4A mRNA; Palmitoyl Coenzyme A results in decreased expression of HNF4A protein |
CTD |
PMID:17992261 |
|
NCBI chr 3:159,902,441...159,965,003
Ensembl chr 3:159,902,441...159,965,003
|
|
G |
Ppara |
peroxisome proliferator activated receptor alpha |
multiple interactions |
ISO |
Palmitoyl Coenzyme A binds to and results in increased activity of PPARA protein Acetylglucosamine inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Atorvastatin promotes the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Atropine inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Budesonide inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Enalapril inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Fenofibrate promotes the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; gamma-Aminobutyric Acid inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; gedunin inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]; Pravastatin promotes the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Pyrazinamide inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Saccharin inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; salicylamide inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Tolazoline inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Tolmetin inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]] |
CTD |
PMID:11139385 PMID:18812576 |
|
NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
|
|
G |
Pparg |
peroxisome proliferator-activated receptor gamma |
multiple interactions |
ISO |
Palmitoyl Coenzyme A binds to and results in increased activity of PPARG protein |
CTD |
PMID:11139385 |
|
NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
|
|
G |
Shbg |
sex hormone binding globulin |
decreases expression |
ISO |
Palmitoyl Coenzyme A results in decreased expression of SHBG mRNA; Palmitoyl Coenzyme A results in decreased expression of SHBG protein |
CTD |
PMID:17992261 |
|
NCBI chr10:56,219,861...56,237,354
Ensembl chr10:56,219,858...56,223,245
|
|
|
G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
multiple interactions |
ISO |
sodium propionate promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] |
CTD |
PMID:31621310 |
|
NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
|
|
G |
Cyp1b1 |
cytochrome P450, family 1, subfamily b, polypeptide 1 |
multiple interactions |
ISO |
sodium propionate promotes the reaction [biochanin A results in increased expression of CYP1B1 mRNA]; sodium propionate promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] |
CTD |
PMID:31621310 |
|
NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
|
|
G |
Mt1 |
metallothionein 1 |
multiple interactions increases expression |
EXP |
[sodium propionate co-treated with Cadmium] results in increased expression of MT1A mRNA; [sodium propionate co-treated with Dexamethasone] results in increased expression of MT1A mRNA sodium propionate results in increased expression of MT1A mRNA |
CTD |
PMID:1597404 |
|
NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
|
|
G |
Ugt1a1 |
UDP glucuronosyltransferase family 1 member A1 |
multiple interactions |
ISO |
sodium propionate promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of UGT1A1 mRNA] |
CTD |
PMID:31621310 |
|
NCBI chr 9:95,295,701...95,302,822
Ensembl chr 9:95,161,157...95,302,822
|
|
|
G |
Hdac8 |
histone deacetylase 8 |
decreases activity |
EXP |
Sodium valproate attenuates the reaction [deoxycorticosterone acetate increases activity of Hdac8 protein in the heart] |
RGD |
PMID:23868068 |
RGD:9681716 |
NCBI chr X:72,163,777...72,370,058
Ensembl chr X:72,163,777...72,370,044
|
|