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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:imidacloprid
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Accession:CHEBI:5870 term browser browse the term
Definition:An imidazolidine that is N-nitroimidazolidin-2-imine bearing a (6-chloro-3-pyridinyl)methyl substituent at position 1.
Synonyms:exact_synonym: 1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine
 related_synonym: 1-((6-chloro-3-pyridinyl)methyl)-N-nitro-2-imidazolidinimine;   1-((6-chloro-3-pyridyl)methyl)-N-nitro-2-imidazolidinimine;   Formula=C9H10ClN5O2;   IMD;   InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13);   InChIKey=YWTYJOPNNQFBPC-UHFFFAOYSA-N;   SMILES=[O-][N+](=O)N=C1NCCN1Cc1ccc(Cl)nc1
 xref: Beilstein:5444268;   CAS:105827-78-9;   CAS:138261-41-3;   KEGG:C11110
 xref_mesh: MESH:C082359
 xref: PMID:11502148;   PMID:11673842;   PMID:11699773;   PMID:11872245;   PMID:12146171;   PMID:12720336;   PMID:14690387;   PMID:14747770;   PMID:15154510;   PMID:15212911;   PMID:15246549;   PMID:15922528;   PMID:16156564;   PMID:16160767;   PMID:16406588;   PMID:16453147;   PMID:16539142;   PMID:16690142;   PMID:16845714;   PMID:18069649;   PMID:18188485;   PMID:18190949;   PMID:18348816;   PMID:18924117;   PMID:18973940;   PMID:18977458;   PMID:19916392;   PMID:19962320;   PMID:22022787;   PMID:22083888;   PMID:22119037;   PMID:22200056;   PMID:22224401;   PMID:22228315;   PMID:22290795;   PMID:22370410;   PMID:22375594;   PMID:22375595;   PMID:22395200;   PMID:22398690;   PMID:22420257;   PMID:22447470;   PMID:22459587;   PMID:22461500;   PMID:24515672;   PMID:25155403;   PMID:25314907;   PMID:25342464;   PMID:25467410;   PMID:25492586;   PMID:25557105;   PMID:25597673;   PMID:25607931;   PMID:25612154;   PMID:25618634;   PMID:25666568;   PMID:25755197;   PMID:25799432;   PMID:25826181;   PMID:25837412;   PMID:25840341;   Patent:EP192060;   Patent:US4742060;   Pesticides:imidacloprid;   Reaxys:5444268;   Wikipedia:Imidacloprid


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imidacloprid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase increases activity EXP imidacloprid results in increased activity of ACHE protein CTD PMID:18080902, PMID:26024013 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Alb albumin multiple interactions EXP [imidacloprid co-treated with sodium arsenate] results in decreased expression of ALB protein CTD PMID:30033815 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Ampd1 adenosine monophosphate deaminase 1 decreases expression EXP imidacloprid results in decreased expression of AMPD1 mRNA CTD PMID:27782041 NCBI chr 2:205,568,934...205,589,961
Ensembl chr 2:205,568,935...205,590,021
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression EXP imidacloprid results in increased expression of BAX protein CTD PMID:27914857 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bche butyrylcholinesterase increases activity EXP imidacloprid results in increased activity of BCHE protein CTD PMID:18080902 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395
JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H increases expression EXP imidacloprid results in increased expression of CACNA1H mRNA CTD PMID:27782041 NCBI chr10:14,730,932...14,789,201
Ensembl chr10:14,730,941...14,788,617
JBrowse link
G Cacng1 calcium voltage-gated channel auxiliary subunit gamma 1 decreases expression EXP imidacloprid results in decreased expression of CACNG1 mRNA CTD PMID:27782041 NCBI chr10:95,921,479...95,934,170
Ensembl chr10:95,921,174...95,934,345
JBrowse link
G Camkk2 calcium/calmodulin-dependent protein kinase kinase 2 decreases expression
multiple interactions
ISO imidacloprid results in decreased expression of CAMKK2 protein
Dietary Fats promotes the reaction [imidacloprid results in decreased expression of CAMKK2 protein]
CTD PMID:27960282 NCBI chr12:39,253,409...39,302,601
Ensembl chr12:39,253,409...39,302,601
JBrowse link
G Cat catalase decreases activity
multiple interactions
EXP imidacloprid results in decreased activity of CAT protein
imidacloprid promotes the reaction [sodium arsenate results in decreased activity of CAT protein]; sodium arsenate promotes the reaction [imidacloprid results in decreased activity of CAT protein]
CTD PMID:20686345, PMID:30033815, PMID:30456172 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccdc81 coiled-coil domain containing 81 increases expression EXP imidacloprid results in increased expression of CCDC81 mRNA CTD PMID:27782041 NCBI chr 1:154,064,132...154,111,999
Ensembl chr 1:154,064,256...154,111,725
JBrowse link
G Cd36 CD36 molecule increases expression ISO imidacloprid results in increased expression of CD36 mRNA CTD PMID:27960282 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Celf6 CUGBP, Elav-like family member 6 increases expression EXP imidacloprid results in increased expression of CELF6 mRNA CTD PMID:27782041 NCBI chr 8:64,364,491...64,428,452
Ensembl chr 8:64,364,741...64,428,386
JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 increases expression EXP imidacloprid results in increased expression of CHRM1 mRNA CTD PMID:26568164 NCBI chr 1:224,869,087...224,885,101
Ensembl chr 1:224,882,439...224,884,205
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 increases expression EXP imidacloprid results in increased expression of CHRM2 protein CTD PMID:18080902 NCBI chr 4:64,089,028...64,091,090
Ensembl chr 4:64,088,900...64,091,090
JBrowse link
G Chrna1 cholinergic receptor nicotinic alpha 1 subunit multiple interactions EXP imidacloprid results in increased activity of [CHRNA1 protein binds to CHRNB2 protein]; LYNX1 protein promotes the reaction [imidacloprid results in increased activity of [CHRNA1 protein binds to CHRNB2 protein]]; LYPD1 protein promotes the reaction [imidacloprid results in increased activity of [CHRNA1 protein binds to CHRNB2 protein]] CTD PMID:19619141 NCBI chr 3:60,445,657...60,460,724
Ensembl chr 3:60,445,666...60,460,724
JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions EXP
ISO
imidacloprid analog inhibits the reaction [Nicotine analog binds to [CHRNA4 protein co-treated with CHRNB2 protein]]; imidacloprid binds to [CHRNA4 protein co-treated with CHRNB2 protein]
imidacloprid inhibits the reaction [Acetylcholine results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]]
CTD PMID:10377228, PMID:10728888, PMID:21538459 NCBI chr 3:176,533,182...176,547,965
Ensembl chr 3:176,527,516...176,548,208
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions EXP
ISO
[NACHRA8 protein co-treated with CHRNB2 protein] affects the susceptibility to imidacloprid; imidacloprid analog inhibits the reaction [Nicotine analog binds to [CHRNA4 protein co-treated with CHRNB2 protein]]; imidacloprid binds to [CHRNA4 protein co-treated with CHRNB2 protein]; imidacloprid binds to [NACHRA1 protein co-treated with CHRNB2 protein]; imidacloprid binds to [NACHRA2 protein co-treated with CHRNB2 protein]; imidacloprid binds to [NACHRALPHA1 protein co-treated with CHRNB2 protein]; imidacloprid binds to [NACHRALPHA2 protein co-treated with CHRNB2 protein]; imidacloprid binds to [NACHRALPHA3 protein co-treated with CHRNB2 protein]; imidacloprid results in increased activity of [CHRNA1 protein binds to CHRNB2 protein]; imidacloprid results in increased activity of [NACHRA1 protein co-treated with CHRNB2 protein]; imidacloprid results in increased activity of [NACHRA1 protein co-treated with NACHRA2 protein co-treated with CHRNB2 protein]; imidacloprid results in increased activity of [NACHRA2 protein co-treated with CHRNB2 protein]; imidacloprid results in increased activity of [NACHRA8 protein co-treated with CHRNB2 protein]; LYNX1 protein promotes the reaction [imidacloprid results in increased activity of [CHRNA1 protein binds to CHRNB2 protein]]; LYPD1 protein promotes the reaction [imidacloprid results in increased activity of [CHRNA1 protein binds to CHRNB2 protein]]
imidacloprid inhibits the reaction [Acetylcholine results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]]
CTD PMID:10377228, PMID:10728888, PMID:16291090, PMID:16981889, PMID:18824080, PMID:19046356, PMID:19619141, PMID:19849723, PMID:21538459, PMID:25459289, PMID:25613467 NCBI chr 2:189,088,570...189,096,785
Ensembl chr 2:189,088,570...189,096,785
JBrowse link
G Cldn1 claudin 1 decreases expression EXP imidacloprid results in decreased expression of CLDN1 mRNA CTD PMID:27792329 NCBI chr11:77,815,216...77,830,373
Ensembl chr11:77,815,181...77,830,416
JBrowse link
G Crb3 crumbs cell polarity complex component 3 increases expression EXP imidacloprid results in increased expression of CRB3 mRNA CTD PMID:27782041 NCBI chr 9:9,982,529...9,986,896
Ensembl chr 9:9,980,720...9,985,630
JBrowse link
G Ctnnd1 catenin delta 1 increases expression EXP imidacloprid results in increased expression of CTNND1 mRNA CTD PMID:27792329 NCBI chr 3:72,001,904...72,053,047
Ensembl chr 3:72,002,152...72,053,049
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression EXP imidacloprid results in decreased expression of CYP17A1 mRNA CTD PMID:27782041 NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases activity
affects expression
multiple interactions
ISO imidacloprid results in increased activity of CYP19A1 protein
imidacloprid affects the expression of CYP19A1 mRNA
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione affects the reaction [imidacloprid affects the expression of CYP19A1 mRNA]
CTD PMID:28750898, PMID:29701941 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G F2rl2 coagulation factor II (thrombin) receptor-like 2 increases expression EXP imidacloprid results in increased expression of F2RL2 mRNA CTD PMID:27782041 NCBI chr 2:26,240,385...26,245,533
Ensembl chr 2:26,240,385...26,245,533
JBrowse link
G Galnt7 polypeptide N-acetylgalactosaminyltransferase 7 increases expression EXP imidacloprid results in increased expression of GALNT7 mRNA CTD PMID:27782041 NCBI chr16:35,935,059...36,062,734
Ensembl chr16:35,934,970...36,062,719
JBrowse link
G Gfap glial fibrillary acidic protein increases expression EXP imidacloprid results in increased expression of GFAP protein CTD PMID:18080902 NCBI chr10:90,990,762...90,999,435
Ensembl chr10:90,990,762...90,999,506
JBrowse link
G Gja1 gap junction protein, alpha 1 decreases expression EXP imidacloprid results in decreased expression of GJA1 mRNA CTD PMID:27792329 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Gpt glutamic--pyruvic transaminase increases activity
multiple interactions
EXP imidacloprid results in increased activity of GPT protein
[imidacloprid co-treated with sodium arsenate] results in increased activity of GPT protein
CTD PMID:30033815 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions
decreases activity
EXP imidacloprid promotes the reaction [sodium arsenate results in decreased activity of GSR protein]; sodium arsenate promotes the reaction [imidacloprid results in decreased activity of GSR protein] CTD PMID:30033815, PMID:30456172 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Hao1 hydroxyacid oxidase 1 decreases expression EXP imidacloprid results in decreased expression of HAO1 mRNA CTD PMID:27782041 NCBI chr 3:127,444,900...127,500,709
Ensembl chr 3:127,444,902...127,500,709
JBrowse link
G Hjv hemojuvelin BMP co-receptor decreases expression EXP imidacloprid results in decreased expression of HJV mRNA CTD PMID:27782041 NCBI chr 2:198,655,437...198,659,318
Ensembl chr 2:198,655,437...198,659,317
JBrowse link
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 decreases expression EXP imidacloprid results in decreased expression of HSD3B2 mRNA CTD PMID:27914857 NCBI chr 2:200,712,895...200,722,429
Ensembl chr 2:202,341,422...202,350,929
JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 decreases expression ISO imidacloprid results in decreased expression of HSP90B1 protein CTD PMID:16884889 NCBI chr 7:27,226,570...27,240,533
Ensembl chr 7:27,226,569...27,240,533
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 decreases expression ISO imidacloprid results in decreased expression of HSPA5 protein CTD PMID:16884889 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 decreases expression ISO imidacloprid results in decreased expression of HSPB1 protein CTD PMID:16884889 NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
JBrowse link
G Hspb7 heat shock protein family B (small) member 7 decreases expression EXP imidacloprid results in decreased expression of HSPB7 mRNA CTD PMID:27782041 NCBI chr 5:159,968,077...159,971,563
Ensembl chr 5:159,967,839...159,971,562
JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C increases expression EXP imidacloprid results in increased expression of HTR2C mRNA CTD PMID:27782041 NCBI chr  X:118,084,520...118,318,040
Ensembl chr  X:118,084,890...118,318,039
JBrowse link
G Itpripl1 ITPRIP like 1 decreases expression EXP imidacloprid results in decreased expression of ITPRIPL1 mRNA CTD PMID:27782041 NCBI chr 3:119,616,473...119,619,865
Ensembl chr 3:119,616,945...119,619,865
JBrowse link
G Klk1 kallikrein 1 decreases expression EXP imidacloprid results in decreased expression of KLK1 mRNA CTD PMID:27782041 NCBI chr 1:100,131,562...100,135,556
Ensembl chr 1:100,059,967...100,203,329
Ensembl chr 1:100,059,967...100,203,329
Ensembl chr 1:100,059,967...100,203,329
JBrowse link
G Krt5 keratin 5 decreases expression EXP imidacloprid results in decreased expression of KRT5 mRNA CTD PMID:27782041 NCBI chr 7:143,320,142...143,324,536
Ensembl chr 7:143,316,920...143,453,546
JBrowse link
G Lep leptin multiple interactions
increases secretion
ISO Dietary Fats promotes the reaction [imidacloprid results in increased secretion of LEP protein]; imidacloprid promotes the reaction [Dietary Fats results in increased secretion of LEP protein] CTD PMID:27960282 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Lynx1 Ly6/neurotoxin 1 multiple interactions EXP LYNX1 protein promotes the reaction [imidacloprid results in increased activity of [CHRNA1 protein binds to CHRNB2 protein]] CTD PMID:19619141 NCBI chr 7:115,982,877...115,988,121
Ensembl chr 7:115,982,876...115,988,090
JBrowse link
G Lypd1 Ly6/Plaur domain containing 1 multiple interactions EXP LYPD1 protein promotes the reaction [imidacloprid results in increased activity of [CHRNA1 protein binds to CHRNB2 protein]] CTD PMID:19619141 NCBI chr13:42,219,884...42,263,024
Ensembl chr13:42,219,887...42,263,024
JBrowse link
G Magel2 MAGE family member L2 increases expression EXP imidacloprid results in increased expression of MAGEL2 mRNA CTD PMID:27782041 NCBI chr 1:123,015,404...123,019,945
Ensembl chr 1:123,015,746...123,019,522
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation ISO imidacloprid results in increased phosphorylation of MAPK1 protein CTD PMID:12460746 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation ISO imidacloprid results in increased phosphorylation of MAPK3 protein CTD PMID:12460746 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mb myoglobin decreases expression EXP imidacloprid results in decreased expression of MB mRNA CTD PMID:27782041 NCBI chr 7:118,101,633...118,108,864
Ensembl chr 7:118,101,634...118,108,864
JBrowse link
G Mybpc2 myosin binding protein C2 increases expression EXP imidacloprid results in increased expression of MYBPC2 mRNA CTD PMID:27782041 NCBI chr 1:100,506,704...100,530,201
Ensembl chr 1:100,506,704...100,530,183
JBrowse link
G Mypn myopalladin decreases expression EXP imidacloprid results in decreased expression of MYPN mRNA CTD PMID:27782041 NCBI chr20:26,988,820...27,074,106
Ensembl chr20:26,988,774...27,074,138
JBrowse link
G Ndufaf2 NADH:ubiquinone oxidoreductase complex assembly factor 2 decreases expression EXP imidacloprid results in decreased expression of NDUFAF2 mRNA CTD PMID:27782041 NCBI chr 2:39,322,145...39,434,535
Ensembl chr 2:39,321,741...39,434,560
JBrowse link
G Neurog3 neurogenin 3 decreases expression EXP imidacloprid results in decreased expression of NEUROG3 mRNA CTD PMID:27782041 NCBI chr20:31,761,419...31,762,893
Ensembl chr20:31,761,405...31,762,893
JBrowse link
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 decreases expression EXP imidacloprid results in decreased expression of NR5A1 mRNA CTD PMID:27914857 NCBI chr 3:22,998,900...23,020,441
Ensembl chr 3:22,999,616...23,020,441
JBrowse link
G Oasl 2'-5'-oligoadenylate synthetase-like increases expression EXP imidacloprid results in increased expression of OASL mRNA CTD PMID:27782041 NCBI chr12:47,444,138...47,456,680
Ensembl chr12:47,444,104...47,456,894
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase increases expression EXP imidacloprid results in increased expression of OGG1 mRNA CTD PMID:27914857 NCBI chr 4:145,282,828...145,289,367
Ensembl chr 4:145,282,797...145,289,326
JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) increases expression
multiple interactions
ISO imidacloprid results in increased expression of PCK2 mRNA
Dietary Fats promotes the reaction [imidacloprid results in increased expression of PCK2 mRNA]; imidacloprid promotes the reaction [Dietary Fats results in increased expression of PCK2 mRNA]
CTD PMID:27960282 NCBI chr15:34,216,735...34,224,357
Ensembl chr15:34,216,833...34,224,193
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 increases expression ISO imidacloprid results in increased expression of PDK4 mRNA CTD PMID:27960282 NCBI chr 4:30,546,772...30,556,774
Ensembl chr 4:30,546,664...30,556,814
JBrowse link
G Pnmt phenylethanolamine-N-methyltransferase multiple interactions
increases expression
EXP imidacloprid promotes the reaction [Nicotine results in increased expression of PNMT protein]
imidacloprid results in increased expression of PNMT protein
CTD PMID:29246838 NCBI chr10:86,340,893...86,342,501
Ensembl chr10:86,340,940...86,342,858
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha decreases expression ISO imidacloprid results in decreased expression of PPARA mRNA CTD PMID:27960282 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha decreases expression ISO imidacloprid results in decreased expression of PPARGC1A protein CTD PMID:27960282 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
JBrowse link
G Prl prolactin multiple interactions ISO [mancozeb co-treated with imidacloprid] results in increased expression of PRL protein CTD PMID:24530807 NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299
JBrowse link
G Rbfox2 RNA binding fox-1 homolog 2 increases expression EXP imidacloprid results in increased expression of RBFOX2 mRNA CTD PMID:27782041 NCBI chr 7:118,157,093...118,396,733
Ensembl chr 7:118,156,946...118,396,728
JBrowse link
G Sirt1 sirtuin 1 decreases expression ISO imidacloprid results in decreased expression of SIRT1 protein CTD PMID:27960282 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Slc22a1 solute carrier family 22 member 1 increases activity ISO imidacloprid results in increased activity of SLC22A1 protein CTD PMID:31364238 NCBI chr 1:48,273,639...48,300,645
Ensembl chr 1:48,273,611...48,300,655
JBrowse link
G Slc22a2 solute carrier family 22 member 2 decreases activity ISO imidacloprid results in decreased activity of SLC22A2 protein CTD PMID:31364238 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
G Slc22a8 solute carrier family 22 member 8 decreases activity ISO imidacloprid results in decreased activity of SLC22A8 protein CTD PMID:31364238 NCBI chr 1:224,799,444...224,818,482
Ensembl chr 1:224,800,252...224,818,482
JBrowse link
G Slc2a2 solute carrier family 2 member 2 increases expression EXP imidacloprid results in increased expression of SLC2A2 mRNA CTD PMID:28850943 NCBI chr 2:114,413,427...114,445,418
Ensembl chr 2:114,413,410...114,445,395
JBrowse link
G Slc2a3 solute carrier family 2 member 3 increases expression EXP imidacloprid results in increased expression of SLC2A3 mRNA CTD PMID:27782041 NCBI chr 4:155,549,991...155,626,018
Ensembl chr 4:155,408,233...155,631,856
JBrowse link
G Slc2a4 solute carrier family 2 member 4 decreases expression ISO
EXP
imidacloprid results in decreased expression of SLC2A4 mRNA
imidacloprid results in decreased expression of SLC2A4 mRNA; imidacloprid results in decreased expression of SLC2A4 protein
CTD PMID:27960282, PMID:28850943 NCBI chr10:56,552,921...56,558,562
Ensembl chr10:56,552,983...56,558,487
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 increases expression ISO imidacloprid results in increased expression of SREBF1 mRNA CTD PMID:27960282 NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009
JBrowse link
G Tacr3 tachykinin receptor 3 increases expression EXP imidacloprid results in increased expression of TACR3 mRNA CTD PMID:27782041 NCBI chr 2:240,021,152...240,118,971
Ensembl chr 2:240,021,152...240,118,971
JBrowse link
G Tada2b transcriptional adaptor 2B increases expression EXP imidacloprid results in increased expression of TADA2B mRNA CTD PMID:27782041 NCBI chr14:79,446,057...79,457,341
Ensembl chr14:79,446,057...79,457,333
JBrowse link
G Th tyrosine hydroxylase multiple interactions
increases expression
EXP [conotoxin AuIB co-treated with triethyl-(beta-4-stilbenoxyethyl)ammonium co-treated with ZM 241385] inhibits the reaction [imidacloprid promotes the reaction [Nicotine results in increased expression of TH mRNA]]; [conotoxin AuIB co-treated with triethyl-(beta-4-stilbenoxyethyl)ammonium co-treated with ZM 241385] inhibits the reaction [imidacloprid results in increased expression of TH mRNA]; [N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide co-treated with exoenzyme C3, Clostridium botulinum] inhibits the reaction [imidacloprid results in increased expression of TH mRNA]; conotoxin AuIB inhibits the reaction [imidacloprid promotes the reaction [Acetylcholine results in increased expression of TH mRNA]]; conotoxin AuIB inhibits the reaction [imidacloprid promotes the reaction [Nicotine results in increased expression of TH mRNA]]; conotoxin AuIB inhibits the reaction [imidacloprid results in increased expression of TH mRNA]; exoenzyme C3, Clostridium botulinum inhibits the reaction [imidacloprid results in increased expression of TH mRNA]; imidacloprid promotes the reaction [Acetylcholine results in increased expression of TH mRNA]; imidacloprid promotes the reaction [Nicotine results in increased expression of TH mRNA]; imidacloprid promotes the reaction [Nicotine results in increased expression of TH protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [imidacloprid results in increased expression of TH mRNA]; triethyl-(beta-4-stilbenoxyethyl)ammonium inhibits the reaction [imidacloprid promotes the reaction [Acetylcholine results in increased expression of TH mRNA]]; triethyl-(beta-4-stilbenoxyethyl)ammonium inhibits the reaction [imidacloprid promotes the reaction [Nicotine results in increased expression of TH mRNA]]; triethyl-(beta-4-stilbenoxyethyl)ammonium inhibits the reaction [imidacloprid results in increased expression of TH mRNA]; ZM 241385 inhibits the reaction [imidacloprid promotes the reaction [Nicotine results in increased expression of TH mRNA]]; ZM 241385 inhibits the reaction [imidacloprid results in increased expression of TH mRNA]
imidacloprid results in increased expression of TH mRNA; imidacloprid results in increased expression of TH protein
CTD PMID:29246838 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
G Thrb thyroid hormone receptor beta affects binding ISO imidacloprid binds to THRB protein CTD PMID:28973306 NCBI chr15:8,890,578...9,239,815
Ensembl chr15:8,890,578...9,086,282
JBrowse link
G Tjp1 tight junction protein 1 decreases expression EXP imidacloprid results in decreased expression of TJP1 mRNA CTD PMID:27792329 NCBI chr 1:126,146,489...126,515,359
Ensembl chr 1:126,146,489...126,227,469
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
ISO Dietary Fats promotes the reaction [imidacloprid results in increased expression of TNF mRNA]; imidacloprid promotes the reaction [Dietary Fats results in increased expression of TNF mRNA] CTD PMID:27960282 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnni2 troponin I2, fast skeletal type decreases expression EXP imidacloprid results in decreased expression of TNNI2 mRNA CTD PMID:27782041 NCBI chr 1:215,609,110...215,611,652
Ensembl chr 1:215,609,036...215,611,658
JBrowse link
G Tshb thyroid stimulating hormone subunit beta multiple interactions ISO [mancozeb co-treated with imidacloprid] results in increased expression of TSHB protein CTD PMID:24530807 NCBI chr 2:205,207,799...205,215,199
Ensembl chr 2:205,207,799...205,212,681
JBrowse link
G Txk TXK tyrosine kinase increases expression EXP imidacloprid results in increased expression of TXK mRNA CTD PMID:27782041 NCBI chr14:38,029,809...38,085,822
Ensembl chr14:38,030,189...38,085,919
JBrowse link
G Unc45b unc-45 myosin chaperone B decreases expression EXP imidacloprid results in decreased expression of UNC45B mRNA CTD PMID:27782041 NCBI chr10:70,262,340...70,290,445
Ensembl chr10:70,262,361...70,290,445
JBrowse link
G Vcl vinculin decreases expression EXP imidacloprid results in decreased expression of VCL mRNA CTD PMID:27792329 NCBI chr15:3,455,211...3,544,738
Ensembl chr15:3,455,211...3,544,702
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      biological role 19734
        xenobiotic 18381
          imidacloprid 79
            (E)-imidacloprid 0
            (Z)-imidacloprid 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19574
                        carbon atom 19563
                          organic molecular entity 19563
                            organic molecule 19488
                              organic cyclic compound 19285
                                organic heterocyclic compound 18410
                                  organic heteromonocyclic compound 16445
                                    pyridines 8381
                                      chloropyridine 966
                                        monochloropyridine 129
                                          2-chloropyridine 129
                                            imidacloprid 79
                                              (E)-imidacloprid 0
                                              (Z)-imidacloprid 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.