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ONTOLOGY REPORT - ANNOTATIONS


Term:ifosfamide
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Accession:CHEBI:5864 term browser browse the term
Definition:The simplest member of the class of ifosfamides that is 1,3,2-oxazaphosphinan-2-amine 2-oxide substituted by 2-chloroethyl groups on both the nitrogen atoms respectively. It is a nitrogen mustard alkylating agent used in the treatment of advanced breast cancer.
Synonyms:exact_synonym: N,3-bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide
 related_synonym: 3-(2-chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide;   Formula=C7H15Cl2N2O2P;   InChI=1S/C7H15Cl2N2O2P/c8-2-4-10-14(12)11(6-3-9)5-1-7-13-14/h1-7H2,(H,10,12);   InChIKey=HOMGKSMUEGBAAB-UHFFFAOYSA-N;   Iphosphamide;   Isofosfamide;   Isophosphamide;   SMILES=ClCCNP1(=O)OCCCN1CCCl;   ifosfamida;   ifosfamidum;   isosfamide
 alt_id: CHEBI:219640
 xref: Beilstein:611835 "Beilstein";   CAS:3778-73-2 "ChemIDplus";   CAS:3778-73-2 "KEGG COMPOUND";   DrugBank:DB01181;   Drug_Central:1421 "DrugCentral";   HMDB:HMDB0015312;   KEGG:C07047;   KEGG:D00343;   LINCS:LSM-5118
 xref_mesh: MESH:D007069
 xref: PMID:11550152 "Europe PMC";   PMID:11669554 "Europe PMC";   Reaxys:5802893 "Reaxys";   Wikipedia:Ifosfamide


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ifosfamide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G 1810037I17Rik RIKEN cDNA 1810037I17 gene JBrowse link 3 122,924,397 122,926,194 RGD:6480464
G 9930012K11Rik RIKEN cDNA 9930012K11 gene JBrowse link 14 70,154,405 70,159,502 RGD:6480464
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A JBrowse link 5 8,567,091 8,748,575 RGD:6480464
G Abcb6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 JBrowse link 1 75,171,640 75,180,392 RGD:6480464
G Abcb9 ATP-binding cassette, sub-family B (MDR/TAP), member 9 JBrowse link 5 124,061,857 124,095,955 RGD:6480464
G Abcg1 ATP binding cassette subfamily G member 1 JBrowse link 17 31,057,694 31,117,984 RGD:6480464
G Abhd4 abhydrolase domain containing 4 JBrowse link 14 54,254,129 54,269,169 RGD:6480464
G Acsl1 acyl-CoA synthetase long-chain family member 1 JBrowse link 8 46,471,037 46,536,051 RGD:6480464
G Agrn agrin JBrowse link 4 156,165,290 156,197,533 RGD:6480464
G Ahr aryl-hydrocarbon receptor JBrowse link 12 35,497,979 35,534,989 RGD:6480464
G Ak4 adenylate kinase 4 JBrowse link 4 101,416,478 101,467,771 RGD:6480464
G Akr1c21 aldo-keto reductase family 1, member C21 JBrowse link 13 4,574,075 4,586,543 RGD:6480464
G Aldh1a3 aldehyde dehydrogenase family 1, subfamily A3 JBrowse link 7 66,390,892 66,427,477 RGD:6480464
G Aldoa aldolase A, fructose-bisphosphate JBrowse link 7 126,795,234 126,800,994 RGD:6480464
G Als2cl ALS2 C-terminal like JBrowse link 9 110,880,120 110,900,530 RGD:6480464
G Ankra2 ankyrin repeat, family A (RFXANK-like), 2 JBrowse link 13 98,263,076 98,274,754 RGD:6480464
G Arhgef10 Rho guanine nucleotide exchange factor (GEF) 10 JBrowse link 8 14,906,412 15,001,085 RGD:6480464
G Asns asparagine synthetase JBrowse link 6 7,675,165 7,693,209 RGD:6480464
G Atf4 activating transcription factor 4 JBrowse link 15 80,255,184 80,257,545 RGD:6480464
G Atxn1 ataxin 1 JBrowse link 13 45,549,755 45,964,991 RGD:6480464
G Aurkb aurora kinase B JBrowse link 11 69,045,624 69,051,664 RGD:6480464
G Avp arginine vasopressin JBrowse link 2 130,580,620 130,582,588 RGD:6480464
G Axl AXL receptor tyrosine kinase JBrowse link 7 25,756,500 25,788,924 RGD:6480464
G B2m beta-2 microglobulin JBrowse link 2 122,147,687 122,153,082 RGD:6480464
G Bax BCL2-associated X protein JBrowse link 7 45,461,695 45,466,903 RGD:6480464
G Bcat1 branched chain aminotransferase 1, cytosolic JBrowse link 6 144,993,835 145,076,157 RGD:6480464
G Bcl2 B cell leukemia/lymphoma 2 JBrowse link 1 106,538,176 106,714,290 RGD:6480464
G Bglap bone gamma carboxyglutamate protein JBrowse link 3 88,383,495 88,384,466 RGD:6480464
G Bhlhe40 basic helix-loop-helix family, member e40 JBrowse link 6 108,660,629 108,666,925 RGD:6480464
G Bnip3 BCL2/adenovirus E1B interacting protein 3 JBrowse link 7 138,890,836 138,909,506 RGD:6480464
G Brd2 bromodomain containing 2 JBrowse link 17 34,112,019 34,122,814 RGD:6480464
G Btg2 BTG anti-proliferation factor 2 JBrowse link 1 134,074,865 134,079,155 RGD:6480464
G Camkk2 calcium/calmodulin-dependent protein kinase kinase 2, beta JBrowse link 5 122,718,380 122,779,522 RGD:6480464
G Cars cysteinyl-tRNA synthetase JBrowse link 7 143,557,230 143,600,090 RGD:6480464
G Casp1 caspase 1 JBrowse link 9 5,298,517 5,307,281 RGD:6480464
G Casp3 caspase 3 JBrowse link 8 46,617,291 46,639,698 RGD:6480464
G Casp9 caspase 9 JBrowse link 4 141,793,612 141,815,978 RGD:6480464
G Cat catalase JBrowse link 2 103,453,904 103,485,153 RGD:6480464
G Ccdc90b coiled-coil domain containing 90B JBrowse link 7 92,561,149 92,582,294 RGD:6480464
G Ccne2 cyclin E2 JBrowse link 4 11,190,433 11,204,779 RGD:6480464
G Ccng2 cyclin G2 JBrowse link 5 93,267,573 93,276,231 RGD:6480464
G Cda cytidine deaminase JBrowse link 4 138,338,528 138,368,311 RGD:6480464
G Cdk6 cyclin-dependent kinase 6 JBrowse link 5 3,341,004 3,531,008 RGD:6480464
G Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) JBrowse link 17 29,090,979 29,100,722 RGD:6480464
G Cers5 ceramide synthase 5 JBrowse link 15 99,735,592 99,772,515 RGD:6480464
G Cmbl carboxymethylenebutenolidase-like (Pseudomonas) JBrowse link 15 31,565,342 31,590,119 RGD:6480464
G Ctdp1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 JBrowse link 18 80,407,959 80,478,739 RGD:6480464
G Cth cystathionase (cystathionine gamma-lyase) JBrowse link 3 157,894,248 157,925,081 RGD:6480464
G Ctsc cathepsin C JBrowse link 7 88,278,024 88,315,861 RGD:6480464
G Cttn cortactin JBrowse link 7 144,435,724 144,471,560 RGD:6480464
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 9 57,687,928 57,703,824 RGD:6480464
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 9 57,676,937 57,683,655 RGD:6480464
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 JBrowse link 17 79,706,940 79,715,061 RGD:6480464
G Cyp2a4 cytochrome P450, family 2, subfamily a, polypeptide 4 JBrowse link 7 26,307,192 26,315,088 RGD:6480464
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 JBrowse link 7 25,897,658 25,926,624 RGD:6480464
G Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29 JBrowse link 19 39,287,044 39,330,713 RGD:6480464
G Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 JBrowse link 19 39,389,556 39,463,103 RGD:6480464
G Cyp2c55 cytochrome P450, family 2, subfamily c, polypeptide 55 JBrowse link 19 39,006,940 39,042,690 RGD:6480464
G Cyp2c65 cytochrome P450, family 2, subfamily c, polypeptide 65 JBrowse link 19 39,061,006 39,093,948 RGD:6480464
G Cyp2c66 cytochrome P450, family 2, subfamily c, polypeptide 66 JBrowse link 19 39,113,898 39,186,756 RGD:6480464
G Cyp2d22 cytochrome P450, family 2, subfamily d, polypeptide 22 JBrowse link 15 82,370,527 82,380,260 RGD:6480464
G Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 JBrowse link 5 145,854,607 145,879,854 RGD:6480464
G Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 JBrowse link 5 137,892,933 137,925,610 RGD:6480464
G Ddit3 DNA-damage inducible transcript 3 JBrowse link 10 127,290,793 127,296,291 RGD:6480464
G Ddit4 DNA-damage-inducible transcript 4 JBrowse link 10 59,949,675 59,951,770 RGD:6480464
G Ddx17 DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 JBrowse link 15 79,527,696 79,546,764 RGD:6480464
G Dgka diacylglycerol kinase, alpha JBrowse link 10 128,720,131 128,745,084 RGD:6480464
G Dlx1 distal-less homeobox 1 JBrowse link 2 71,528,113 71,533,981 RGD:6480464
G Dnajb2 DnaJ heat shock protein family (Hsp40) member B2 JBrowse link 1 75,236,395 75,245,692 RGD:6480464
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 JBrowse link 12 44,205,897 44,210,068 RGD:6480464
G Dnmbp dynamin binding protein JBrowse link 19 43,846,815 43,940,232 RGD:6480464
G Dpm3 dolichyl-phosphate mannosyltransferase polypeptide 3 JBrowse link 3 89,257,065 89,267,079 RGD:6480464
G Dusp22 dual specificity phosphatase 22 JBrowse link 13 30,660,059 30,711,232 RGD:6480464
G Efna1 ephrin A1 JBrowse link 3 89,271,730 89,280,951 RGD:6480464
G Eif1 eukaryotic translation initiation factor 1 JBrowse link 11 100,319,949 100,322,099 RGD:6480464
G Eif3c eukaryotic translation initiation factor 3, subunit C JBrowse link 7 126,546,911 126,566,366 RGD:6480464
G Elf4 E74-like factor 4 (ets domain transcription factor) JBrowse link X 48,411,049 48,463,132 RGD:6480464
G Elk4 ELK4, member of ETS oncogene family JBrowse link 1 132,007,565 132,026,448 RGD:6480464
G Eno2 enolase 2, gamma neuronal JBrowse link 6 124,760,053 124,769,673 RGD:6480464
G Ep400 E1A binding protein p400 JBrowse link 5 110,664,373 110,770,927 RGD:6480464
G Ero1l ERO1-like (S. cerevisiae) JBrowse link 14 45,283,087 45,318,572 RGD:6480464
G Exoc7 exocyst complex component 7 JBrowse link 11 116,287,998 116,306,750 RGD:6480464
G Fabp3 fatty acid binding protein 3, muscle and heart JBrowse link 4 130,308,738 130,315,463 RGD:6480464
G Fam162a family with sequence similarity 162, member A JBrowse link 16 36,043,844 36,071,561 RGD:6480464
G Fam210b family with sequence similarity 210, member B JBrowse link 2 172,345,570 172,355,749 RGD:6480464
G Fam214a family with sequence similarity 214, member A JBrowse link 9 74,952,867 75,032,468 RGD:6480464
G Fam89a family with sequence similarity 89, member A JBrowse link 8 124,740,257 124,751,866 RGD:6480464
G Fasl Fas ligand (TNF superfamily, member 6) JBrowse link 1 161,780,691 161,788,495 RGD:6480464
G Fbxo22 F-box protein 22 JBrowse link 9 55,208,935 55,224,433 RGD:6480464
G Fbxo30 F-box protein 30 JBrowse link 10 11,281,330 11,305,750 RGD:6480464
G Fech ferrochelatase JBrowse link 18 64,456,542 64,489,098 RGD:6480464
G Flvcr2 feline leukemia virus subgroup C cellular receptor 2 JBrowse link 12 85,746,539 85,813,586 RGD:6480464
G Fosl1 fos-like antigen 1 JBrowse link 19 5,447,698 5,455,938 RGD:6480464
G Gars glycyl-tRNA synthetase JBrowse link 6 55,038,001 55,079,504 RGD:6480464
G Gclc glutamate-cysteine ligase, catalytic subunit JBrowse link 9 77,754,535 77,794,489 RGD:6480464
G Gclm glutamate-cysteine ligase, modifier subunit JBrowse link 3 122,245,487 122,267,215 RGD:6480464
G Gdf15 growth differentiation factor 15 JBrowse link 8 70,629,393 70,632,470 RGD:6480464
G Gm20348 predicted gene, 20348 JBrowse link 12 4,810,475 4,817,155 RGD:6480464
G Gpat3 glycerol-3-phosphate acyltransferase 3 JBrowse link 5 100,845,665 100,899,102 RGD:6480464
G Gpr87 G protein-coupled receptor 87 JBrowse link 3 59,178,904 59,195,163 RGD:6480464
G Gpr88 G-protein coupled receptor 88 JBrowse link 3 116,249,654 116,253,540 RGD:6480464
G Gpx1 glutathione peroxidase 1 JBrowse link 9 108,339,080 108,340,342 RGD:6480464
G Gpx3 glutathione peroxidase 3 JBrowse link 11 54,902,854 54,910,387 RGD:6480464
G Gsr glutathione reductase JBrowse link 8 33,653,238 33,698,162 RGD:6480464
G Gstp1 glutathione S-transferase, pi 1 JBrowse link 19 4,035,411 4,037,912 RGD:6480464
G H2-M2 histocompatibility 2, M region locus 2 JBrowse link 17 37,480,851 37,483,554 RGD:6480464
G H2-M3 histocompatibility 2, M region locus 3 JBrowse link 17 37,270,234 37,274,485 RGD:6480464
G H2-Q1 histocompatibility 2, Q region locus 1 JBrowse link 17 35,320,525 35,328,142 RGD:6480464
G Herc3 hect domain and RLD 3 JBrowse link 6 58,831,455 58,920,398 RGD:6480464
G Hif1a hypoxia inducible factor 1, alpha subunit JBrowse link 12 73,901,324 73,947,554 RGD:6480464
G Hspa1b heat shock protein 1B JBrowse link 17 34,956,429 34,959,238 RGD:6480464
G Iars isoleucine-tRNA synthetase JBrowse link 13 49,682,130 49,734,267 RGD:6480464
G Ids iduronate 2-sulfatase JBrowse link X 70,343,069 70,385,834 RGD:6480464
G Ifna2 interferon alpha 2 JBrowse link 4 88,683,207 88,683,779 RGD:6480464
G Ifnb1 interferon beta 1, fibroblast JBrowse link 4 88,522,025 88,522,794 RGD:6480464
G Igf2r insulin-like growth factor 2 receptor JBrowse link 17 12,682,406 12,769,706 RGD:6480464
G Il19 interleukin 19 JBrowse link 1 130,932,656 130,945,457 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 2 129,364,569 129,371,164 RGD:6480464
G Il6 interleukin 6 JBrowse link 5 30,013,114 30,019,975 RGD:6480464
G Inka2 inka box actin regulator 2 JBrowse link 3 105,704,599 105,720,842 RGD:6480464
G Insig2 insulin induced gene 2 JBrowse link 1 121,304,353 121,332,662 RGD:6480464
G Itfg2 integrin alpha FG-GAP repeat containing 2 JBrowse link 6 128,409,047 128,424,927 RGD:6480464
G Itgb1 integrin beta 1 (fibronectin receptor beta) JBrowse link 8 128,685,654 128,733,579 RGD:6480464
G Kat6b K(lysine) acetyltransferase 6B JBrowse link 14 21,499,216 21,672,478 RGD:6480464
G Kdm3a lysine (K)-specific demethylase 3A JBrowse link 6 71,588,970 71,632,990 RGD:6480464
G Keap1 kelch-like ECH-associated protein 1 JBrowse link 9 21,229,730 21,239,332 RGD:6480464
G Krt15 keratin 15 JBrowse link 11 100,131,759 100,135,949 RGD:6480464
G Krt19 keratin 19 JBrowse link 11 100,140,810 100,145,926 RGD:6480464
G Lama3 laminin, alpha 3 JBrowse link 18 12,333,417 12,583,013 RGD:6480464
G Lmcd1 LIM and cysteine-rich domains 1 JBrowse link 6 112,273,758 112,330,423 RGD:6480464
G Ltn1 listerin E3 ubiquitin protein ligase 1 JBrowse link 16 87,376,651 87,432,619 RGD:6480464
G Mafg v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian) JBrowse link 11 120,625,117 120,634,955 RGD:6480464
G Mdm2 transformed mouse 3T3 cell double minute 2 JBrowse link 10 117,688,875 117,710,758 RGD:6480464
G Me1 malic enzyme 1, NADP(+)-dependent, cytosolic JBrowse link 9 86,581,363 86,695,914 RGD:6480464
G Mmp9 matrix metallopeptidase 9 JBrowse link 2 164,940,326 164,955,850 RGD:6480464
G Mr1 major histocompatibility complex, class I-related JBrowse link 1 155,127,874 155,146,814 RGD:6480464
G Mt2 metallothionein 2 JBrowse link 8 94,172,618 94,173,567 RGD:6480464
G Mtdh metadherin JBrowse link 15 34,082,442 34,143,537 RGD:6480464
G Mtfp1 mitochondrial fission process 1 JBrowse link 11 4,091,481 4,095,431 RGD:6480464
G Mxi1 MAX interactor 1, dimerization protein JBrowse link 19 53,310,128 53,373,293 RGD:6480464
G Ncapd2 non-SMC condensin I complex, subunit D2 JBrowse link 6 125,168,007 125,192,100 RGD:6480464
G Nedd9 neural precursor cell expressed, developmentally down-regulated gene 9 JBrowse link 13 41,309,916 41,487,362 RGD:6480464
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 JBrowse link 2 75,675,513 75,704,663 RGD:6480464
G Nin ninein JBrowse link 12 70,011,435 70,113,811 RGD:6480464
G Nos2 nitric oxide synthase 2, inducible JBrowse link 11 78,920,787 78,960,226 RGD:6480464
G Npy1r neuropeptide Y receptor Y1 JBrowse link 8 66,697,149 66,706,800 RGD:6480464
G Nqo1 NAD(P)H dehydrogenase, quinone 1 JBrowse link 8 107,388,225 107,403,205 RGD:6480464
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 JBrowse link 16 38,248,349 38,294,849 RGD:6480464
G Nrep neuronal regeneration related protein JBrowse link 18 33,437,019 33,464,365 RGD:6480464
G Ntpcr nucleoside-triphosphatase, cancer-related JBrowse link 8 125,729,975 125,748,235 RGD:6480464
G Nuak1 NUAK family, SNF1-like kinase, 1 JBrowse link 10 84,370,900 84,440,668 RGD:6480464
G Osgin1 oxidative stress induced growth inhibitor 1 JBrowse link 8 119,425,882 119,446,257 RGD:6480464
G P4ha1 procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide JBrowse link 10 59,323,197 59,373,304 RGD:6480464
G Pank1 pantothenate kinase 1 JBrowse link 19 34,806,935 34,883,423 RGD:6480464
G Pde8a phosphodiesterase 8A JBrowse link 7 81,213,265 81,334,535 RGD:6480464
G Pdia5 protein disulfide isomerase associated 5 JBrowse link 16 35,397,308 35,490,919 RGD:6480464
G Pdk1 pyruvate dehydrogenase kinase, isoenzyme 1 JBrowse link 2 71,873,215 71,903,858 RGD:6480464
G Phgdh 3-phosphoglycerate dehydrogenase JBrowse link 3 98,313,171 98,339,969 RGD:6480464
G Phlda3 pleckstrin homology like domain, family A, member 3 JBrowse link 1 135,766,085 135,769,134 RGD:6480464
G Pidd1 p53 induced death domain protein 1 JBrowse link 7 141,438,113 141,447,565 RGD:6480464
G Plaur plasminogen activator, urokinase receptor JBrowse link 7 24,460,937 24,475,970 RGD:6480464
G Pmepa1 prostate transmembrane protein, androgen induced 1 JBrowse link 2 173,224,458 173,276,731 RGD:6480464
G Podxl podocalyxin-like JBrowse link 6 31,519,493 31,563,937 RGD:6480464
G Por P450 (cytochrome) oxidoreductase JBrowse link 5 135,670,040 135,735,326 RGD:6480464
G Pparg peroxisome proliferator activated receptor gamma JBrowse link 6 115,360,879 115,490,404 RGD:6480464
G Ppfibp1 PTPRF interacting protein, binding protein 1 (liprin beta 1) JBrowse link 6 146,886,609 147,032,025 RGD:6480464
G Ppig peptidyl-prolyl isomerase G (cyclophilin G) JBrowse link 2 69,722,753 69,754,059 RGD:6480464
G Ppm1d protein phosphatase 1D magnesium-dependent, delta isoform JBrowse link 11 85,311,254 85,347,071 RGD:6480464
G Prc1 protein regulator of cytokinesis 1 JBrowse link 7 80,294,445 80,316,259 RGD:6480464
G Prdm1 PR domain containing 1, with ZNF domain JBrowse link 10 44,437,174 44,528,558 RGD:6480464
G Prkab1 protein kinase, AMP-activated, beta 1 non-catalytic subunit JBrowse link 5 116,013,586 116,024,503 RGD:6480464
G Prkab2 protein kinase, AMP-activated, beta 2 non-catalytic subunit JBrowse link 3 97,658,211 97,673,812 RGD:6480464
G Psat1 phosphoserine aminotransferase 1 JBrowse link 19 15,905,123 15,925,059 RGD:6480464
G Pspc1 paraspeckle protein 1 JBrowse link 14 56,722,441 56,778,318 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 1 150,100,031 150,108,234 RGD:6480464
G Pycr1 pyrroline-5-carboxylate reductase 1 JBrowse link 11 120,635,712 120,643,769 RGD:6480464
G Pygl liver glycogen phosphorylase JBrowse link 12 70,190,815 70,227,683 RGD:6480464
G Rab31 RAB31, member RAS oncogene family JBrowse link 17 65,651,726 65,772,752 RGD:6480464
G Rffl ring finger and FYVE like domain containing protein JBrowse link 11 82,803,819 82,871,236 RGD:6480464
G Rit1 Ras-like without CAAX 1 JBrowse link 3 88,716,839 88,731,048 RGD:6480464
G Rlf rearranged L-myc fusion sequence JBrowse link 4 121,145,883 121,215,121 RGD:6480464
G Rnf121 ring finger protein 121 JBrowse link 7 102,019,137 102,072,437 RGD:6480464
G Ro60 Ro60, Y RNA binding protein JBrowse link 1 143,750,790 143,777,063 RGD:6480464
G Rps27l ribosomal protein S27-like JBrowse link 9 66,944,624 66,949,522 RGD:6480464
G Rrm2b ribonucleotide reductase M2 B (TP53 inducible) JBrowse link 15 37,923,952 37,961,119 RGD:6480464
G Rrp12 ribosomal RNA processing 12 homolog (S. cerevisiae) JBrowse link 19 41,859,483 41,896,153 RGD:6480464
G Rsrc2 arginine/serine-rich coiled-coil 2 JBrowse link 5 123,728,426 123,749,429 RGD:6480464
G Sars seryl-aminoacyl-tRNA synthetase JBrowse link 3 108,424,864 108,445,259 RGD:6480464
G Sertad1 SERTA domain containing 1 JBrowse link 7 27,486,953 27,490,316 RGD:6480464
G Sesn1 sestrin 1 JBrowse link 10 41,810,574 41,908,436 RGD:6480464
G Sfn stratifin JBrowse link 4 133,600,556 133,602,168 RGD:6480464
G Sh3tc1 SH3 domain and tetratricopeptide repeats 1 JBrowse link 5 35,697,180 35,739,987 RGD:6480464
G Siah2 siah E3 ubiquitin protein ligase 2 JBrowse link 3 58,674,949 58,692,439 RGD:6480464
G Sipa1l2 signal-induced proliferation-associated 1 like 2 JBrowse link 8 125,418,068 125,569,863 RGD:6480464
G Siva1 SIVA1, apoptosis-inducing factor JBrowse link 12 112,644,828 112,649,152 RGD:6480464
G Slc12a8 solute carrier family 12 (potassium/chloride transporters), member 8 JBrowse link 16 33,517,328 33,664,138 RGD:6480464
G Slc1a5 solute carrier family 1 (neutral amino acid transporter), member 5 JBrowse link 7 16,781,334 16,798,274 RGD:6480464
G Slc22a5 solute carrier family 22 (organic cation transporter), member 5 JBrowse link 11 53,864,542 53,891,796 RGD:6480464
G Slc25a20 solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20 JBrowse link 9 108,662,136 108,684,642 RGD:6480464
G Slc2a1 solute carrier family 2 (facilitated glucose transporter), member 1 JBrowse link 4 119,108,745 119,137,330 RGD:6480464
G Slc3a2 solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 JBrowse link 19 8,706,882 8,723,369 RGD:6480464
G Slc6a9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 JBrowse link 4 117,835,258 117,869,305 RGD:6480464
G Slc7a5 solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 JBrowse link 8 121,881,146 121,907,686 RGD:6480464
G Son Son DNA binding protein JBrowse link 16 91,647,824 91,679,192 RGD:6480464
G Spsb1 splA/ryanodine receptor domain and SOCS box containing 1 JBrowse link 4 149,896,283 149,955,006 RGD:6480464
G Sqstm1 sequestosome 1 JBrowse link 11 50,200,152 50,210,820 RGD:6480464
G Srd5a3 steroid 5 alpha-reductase 3 JBrowse link 5 76,140,273 76,155,503 RGD:6480464
G Srxn1 sulfiredoxin 1 homolog (S. cerevisiae) JBrowse link 2 152,105,524 152,111,376 RGD:6480464
G Sulf2 sulfatase 2 JBrowse link 2 166,073,899 166,155,683 RGD:6480464
G Taldo1 transaldolase 1 JBrowse link 7 141,392,160 141,402,976 RGD:6480464
G Tars threonyl-tRNA synthetase JBrowse link 15 11,383,663 11,399,658 RGD:6480464
G Tbxas1 thromboxane A synthase 1, platelet JBrowse link 6 38,864,159 39,084,590 RGD:6480464
G Tfap2a transcription factor AP-2, alpha JBrowse link 13 40,713,802 40,738,238 RGD:6480464
G Thbs2 thrombospondin 2 JBrowse link 17 14,665,500 14,694,262 RGD:6480464
G Tigar Trp53 induced glycolysis regulatory phosphatase JBrowse link 6 127,085,116 127,109,552 RGD:6480464
G Timm17b translocase of inner mitochondrial membrane 17b JBrowse link X 7,899,336 7,907,652 RGD:6480464
G Tlr4 toll-like receptor 4 JBrowse link 4 66,827,551 66,846,581 RGD:6480464
G Tmem94 transmembrane protein 94 JBrowse link 11 115,765,419 115,799,033 RGD:6480464
G Tmtc2 transmembrane and tetratricopeptide repeat containing 2 JBrowse link 10 105,187,663 105,574,479 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 17 35,199,367 35,202,007 RGD:6480464
G Tnfaip8 tumor necrosis factor, alpha-induced protein 8 JBrowse link 18 49,979,427 50,093,229 RGD:6480464
G Tnfsf9 tumor necrosis factor (ligand) superfamily, member 9 JBrowse link 17 57,105,287 57,107,758 RGD:6480464
G Top1 topoisomerase (DNA) I JBrowse link 2 160,645,897 160,722,764 RGD:6480464
G Top2a topoisomerase (DNA) II alpha JBrowse link 11 98,992,947 99,024,199 RGD:6480464
G Trafd1 TRAF type zinc finger domain containing 1 JBrowse link 5 121,371,725 121,386,570 RGD:6480464
G Triap1 TP53 regulated inhibitor of apoptosis 1 JBrowse link 5 115,341,231 115,343,553 RGD:6480464
G Trp53 transformation related protein 53 JBrowse link 11 69,580,348 69,591,873 RGD:6480464
G Trp53inp1 transformation related protein 53 inducible nuclear protein 1 JBrowse link 4 11,156,441 11,174,379 RGD:6480464
G Tspan12 tetraspanin 12 JBrowse link 6 21,771,391 21,879,596 RGD:6480464
G Txn1 thioredoxin 1 JBrowse link 4 57,943,373 57,956,411 RGD:6480464
G Txnrd1 thioredoxin reductase 1 JBrowse link 10 82,833,951 82,897,724 RGD:6480464
G Ube2g2 ubiquitin-conjugating enzyme E2G 2 JBrowse link 10 77,622,321 77,645,990 RGD:6480464
G Unkl unkempt family like zinc finger JBrowse link 17 25,188,361 25,234,443 RGD:6480464
G Usp3 ubiquitin specific peptidase 3 JBrowse link 9 66,514,639 66,593,148 RGD:6480464
G Vars valyl-tRNA synthetase JBrowse link 17 35,000,907 35,016,329 RGD:6480464
G Vegfa vascular endothelial growth factor A JBrowse link 17 46,016,993 46,032,377 RGD:6480464
G Wars tryptophanyl-tRNA synthetase JBrowse link 12 108,860,030 108,894,175 RGD:6480464
G Wdr63 WD repeat domain 63 JBrowse link 3 146,040,526 146,108,100 RGD:6480464
G Wwc2 WW, C2 and coiled-coil domain containing 2 JBrowse link 8 47,826,082 47,990,544 RGD:6480464
G Xbp1 X-box binding protein 1 JBrowse link 11 5,520,641 5,525,993 RGD:6480464
G Xpc xeroderma pigmentosum, complementation group C JBrowse link 6 91,489,305 91,515,888 RGD:6480464
G Yeats2 YEATS domain containing 2 JBrowse link 16 20,141,053 20,232,573 RGD:6480464
G Zfp266 zinc finger protein 266 JBrowse link 9 20,495,068 20,521,419 RGD:6480464
G Zmat3 zinc finger matrin type 3 JBrowse link 3 32,334,792 32,365,665 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20752
    role 20730
      biological role 20729
        xenobiotic 18727
          ifosfamide 244
Path 2
Term Annotations click to browse term
  CHEBI ontology 20752
    subatomic particle 20745
      composite particle 20745
        hadron 20745
          baryon 20745
            nucleon 20745
              atomic nucleus 20745
                atom 20745
                  main group element atom 20665
                    p-block element atom 20665
                      chalcogen 19873
                        oxygen atom 19861
                          oxygen molecular entity 19861
                            hydroxides 19606
                              oxoacid 18960
                                pnictogen oxoacid 8578
                                  phosphorus oxoacid 8471
                                    phosphoric acids 7360
                                      phosphoric acid 7360
                                        phosphoramide 990
                                          phosphorodiamide 971
                                            ifosfamides 244
                                              ifosfamide 244
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.