Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:methysergide
go back to main search page
Accession:CHEBI:584020 term browser browse the term
Definition:A synthetic ergot alkaloid, structurally related to the oxytocic agent methylergonovine and to the potent hallucinogen LSD and used prophylactically to reduce the frequency and intensity of severe vascular headaches.
Synonyms:exact_synonym: (8R)-N-[1-hydroxymethyl(propyl)]-1,6-dimethyl-9,10-didehydroergoline-8-carboxamide
 related_synonym: (+)-9,10-Didehydro-N-(1-(hydroxymethyl)propyl)-1,6-dimethylergoline-8beta-carboxamide;   (+)-N-(1-(Hydroxymethyl)propyl)-1-methyl-D-lysergamide;   1-Methyl-D-lysergic acid butanolamide;   1-Methyl-dextro-lysergic acid (+)-1-hydroxy-2-butylamide;   1-Methyllysergic acid butanolamide;   1-Methylmethylergonovine;   9,10-Didehydro-N-(1-(hydroxymethyl)propyl)-1,6-dimethylergoline-8-carboxamide;   Formula=C21H27N3O2;   InChI=1S/C21H27N3O2/c1-4-15(12-25)22-21(26)14-8-17-16-6-5-7-18-20(16)13(10-23(18)2)9-19(17)24(3)11-14/h5-8,10,14-15,19,25H,4,9,11-12H2,1-3H3,(H,22,26)/t14-,15?,19-/m1/s1;   InChIKey=KPJZHOPZRAFDTN-NQUBZZJWSA-N;   N-(1-(Hydroxymethyl)propyl)-1-methyl-dextro-(+)-lysergamide;   SMILES=[H][C@@]12Cc3cn(C)c4cccc(C1=C[C@H](CN2C)C(=O)NC(CC)CO)c34;   methysergidum;   metisergida
 alt_id: CHEBI:6893
 xref: Beilstein:765986 "Beilstein";   CAS:361-37-5 "ChemIDplus";   DrugBank:DB00247;   KEGG:C07199;   KEGG:D02357
 xref_mesh: MESH:D008784
 xref: Patent:GB854569;   Patent:US3113133


show annotations for term's descendants       view all columns           Sort by:
 
methysergide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb4 ATP binding cassette subfamily B member 4 JBrowse link 4 22,133,984 22,192,687 RGD:6480464
G Adra1a adrenoceptor alpha 1A JBrowse link 15 43,296,997 43,398,314 RGD:6480464
G Calca calcitonin-related polypeptide alpha JBrowse link 1 184,184,018 184,188,922 RGD:6480464
G Htr1b 5-hydroxytryptamine receptor 1B JBrowse link 8 89,113,984 89,130,830 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19657
    role 19601
      biological role 19599
        pharmacological role 18680
          neurotransmitter agent 16228
            serotonergic drug 3850
              serotonergic antagonist 2225
                methysergide 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19657
    subatomic particle 19653
      composite particle 19653
        hadron 19653
          baryon 19653
            nucleon 19653
              atomic nucleus 19653
                atom 19653
                  main group element atom 19534
                    p-block element atom 19534
                      carbon group element atom 19417
                        carbon atom 19409
                          organic molecular entity 19409
                            organic group 18338
                              organic divalent group 18329
                                organodiyl group 18329
                                  carbonyl group 18218
                                    carbonyl compound 18218
                                      carboxylic acid 17918
                                        carboacyl group 16941
                                          univalent carboacyl group 16941
                                            carbamoyl group 16621
                                              carboxamide 16621
                                                monocarboxylic acid amide 13181
                                                  methysergide 4
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.