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ONTOLOGY REPORT - ANNOTATIONS


Term:hydroxyzine
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Accession:CHEBI:5818 term browser browse the term
Definition:A N-alkylpiperazine that is piperzine in which the nitrogens atoms are substituted by 2-(2-hydroxyethoxy)ethyl and (4-chlorophenyl)(phenyl)methyl groups respectively.
Synonyms:exact_synonym: 2-(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)ethanol
 related_synonym: Formula=C21H27ClN2O2;   Hychotine;   Hydroxine;   Hydroxizine;   Hydroxizinum;   Hydroxycine;   Hydroxyzin;   InChI=1S/C21H27ClN2O2/c22-20-8-6-19(7-9-20)21(18-4-2-1-3-5-18)24-12-10-23(11-13-24)14-16-26-17-15-25/h1-9,21,25H,10-17H2;   InChIKey=ZQDWXGKKHFNSQK-UHFFFAOYSA-N;   SMILES=OCCOCCN1CCN(CC1)C(c1ccccc1)c1ccc(Cl)cc1;   hidroxizina;   hydroxyzinum
 xref: Beilstein:321392 "Beilstein";   CAS:68-88-2 "ChemIDplus";   CAS:68-88-2 "KEGG COMPOUND";   DrugBank:DB00557;   Drug_Central:1400 "DrugCentral";   HMDB:HMDB0014697;   KEGG:C07045;   KEGG:D08054;   LINCS:LSM-5103
 xref_mesh: MESH:D006919
 xref: PMID:15233966 "Europe PMC";   PMID:19057127 "Europe PMC";   PMID:19348661 "Europe PMC";   Patent:US2899436;   Reaxys:321392 "Reaxys";   VSDB:2977;   Wikipedia:Hydroxyzine


show annotations for term's descendants       view all columns           Sort by:
 
hydroxyzine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb4 ATP binding cassette subfamily B member 4 JBrowse link 4 22,133,984 22,192,687 RGD:6480464
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:6480464
G Hexb hexosaminidase subunit beta JBrowse link 2 27,983,925 28,003,260 RGD:6480464
G Hrh1 histamine receptor H 1 JBrowse link 4 146,374,596 146,458,148 RGD:6480464
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:6480464
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:6480464
G Slc22a2 solute carrier family 22 member 2 JBrowse link 1 48,318,025 48,360,219 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19654
    role 19598
      application 19220
        pharmaceutical 19081
          drug 19081
            dermatologic drug 12398
              hydroxyzine 7
                hydroxyzine hydrochloride 0
                hydroxyzine pamoate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19654
    subatomic particle 19650
      composite particle 19650
        hadron 19650
          baryon 19650
            nucleon 19650
              atomic nucleus 19650
                atom 19650
                  main group element atom 19531
                    main group molecular entity 19531
                      s-block molecular entity 19314
                        hydrogen molecular entity 19303
                          hydrides 18231
                            inorganic hydride 17095
                              pnictogen hydride 17053
                                nitrogen hydride 16874
                                  azane 16551
                                    ammonia 16548
                                      organic amino compound 16547
                                        tertiary amino compound 8517
                                          N-alkylpiperazine 2950
                                            hydroxyzine 7
                                              hydroxyzine hydrochloride 0
                                              hydroxyzine pamoate 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.