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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:5790 term browser browse the term
Definition:A morphinane alkaloid that is a hydrogenated ketone derivative of morphine. A semi-synthetic drug, it is a centrally acting pain medication of the opioid class.
Synonyms:exact_synonym: 3-hydroxy-17-methyl-4,5alpha-epoxymorphinan-6-one
 related_synonym: (-)-(5R)-4,5-Epoxy-3-hydroxy-9alpha-methylmorphinan-6-one;   4,5-Epoxy-3-hydroxy-17-methylmorphinan-6-one;   4,5alpha-Epoxy-3-hydroxy-17-methyl-6-morphinanone;   6-Deoxy-7,8-dihydro-6-oxomorphine;   7,8-Dihydromorphinone;   Dihydromorfinon;   Dihydromorphinone;   Dimorphone;   Formula=C17H19NO3;   Hydromorfona;   Idromorfone;   InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2,4,10-11,16,19H,3,5-8H2,1H3/t10-,11+,16-,17-/m0/s1;   InChIKey=WVLOADHCBXTIJK-YNHQPCIGSA-N;   SMILES=[H][C@]12CCC(=O)[C@@H]3Oc4c(O)ccc5C[C@H]1N(C)CC[C@@]23c45;   hidromorfona;   hydromorphonum
 xref: Beilstein:42553;   CAS:466-99-9;   DrugBank:DB00327;   Drug_Central:1393;   KEGG:C07042;   KEGG:D08047
 xref_mesh: MESH:D004091
 xref: PMID:11305075;   PMID:12799972;   PMID:15907647;   PMID:18789923;   PMID:19227610;   PMID:3211162;   Patent:US2628962;   Patent:US2649454;   Patent:US2654756;   VSDB:2976;   Wikipedia:Dihydromorphinone

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hydromorphone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr3a 5-hydroxytryptamine receptor 3A affects activity ISO Hydromorphone affects the activity of HTR3A protein CTD PMID:18635474 NCBI chr 8:49,242,018...49,254,475
Ensembl chr 8:49,242,020...49,254,389
JBrowse link
G Oprm1 opioid receptor, mu 1 increases activity ISO Hydromorphone results in increased activity of OPRM1 protein CTD PMID:32734307 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    role 19751
      biological role 19751
        pharmacological role 18837
          analgesic 13308
            opioid analgesic 638
              hydromorphone 2
                hydromorphone hydrochloride 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      carbon group element atom 19619
                        carbon atom 19609
                          organic molecular entity 19609
                            heteroorganic entity 19278
                              organonitrogen compound 18544
                                alkaloid 5686
                                  isoquinoline alkaloid 1139
                                    morphinane alkaloid 663
                                      morphinan 638
                                        hydromorphone 2
                                          hydromorphone hydrochloride 0
paths to the root