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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Homatropine
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Accession:CHEBI:5747 term browser browse the term
Definition:A monocarboxylic acid that has formula C16H21NO3.
Synonyms:related_synonym: (+/-)-Mandelyltropine;   Formula=C16H21NO3;   InChI=1S/C16H21NO3/c1-17-12-7-8-13(17)10-14(9-12)20-16(19)15(18)11-5-3-2-4-6-11/h2-6,12-15,18H,7-10H2,1H3/t12-,13+,14+,15?;   InChIKey=ZTVIKZXZYLEVOL-MCOXGKPRSA-N;   SMILES=CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)C(O)c1ccccc1;   homatropin;   homatropine hydrobromide;   homatropine sulfate;   homoatropine;   mandelyltropeine;   tropine mandelate
 xref: CAS:87-00-3;   Drug_Central:1379;   KEGG:C07814
 xref_mesh: MESH:C100236


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Homatropine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ces1d carboxylesterase 1D multiple interactions
affects binding
ISO CES1 protein binds to and results in increased metabolism of homatropine
homatropine binds to CES1 protein
CTD PMID:12679808, PMID:12773168 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO homatropine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      chemical role 19250
        donor 18378
          Bronsted acid 18241
            oxoacid 18193
              carbon oxoacid 18073
                carboxylic acid 18061
                  monocarboxylic acid 17407
                    Homatropine 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19574
                        carbon atom 19563
                          organic molecular entity 19563
                            organic group 18495
                              organic divalent group 18488
                                organodiyl group 18488
                                  carbonyl group 18391
                                    carbonyl compound 18391
                                      carboxylic acid 18061
                                        monocarboxylic acid 17407
                                          Homatropine 2
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