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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:echinocandin
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Accession:CHEBI:57248 term browser browse the term
Definition:Any one of a family of large lipopeptides that are inhibitors of the enzyme 1,3-beta-glucan synthase, thus damaging fungal cell walls. Echinocandins are fungicidal against most Candida spp and fungistatic against Aspergillus spp.
Synonyms:related_synonym: echinocandins



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caspofungin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hnmt histamine N-methyltransferase decreases activity ISO caspofungin results in decreased activity of HNMT protein CTD PMID:12921242 NCBI chr 3:6,591,804...6,623,821
Ensembl chr 3:6,591,463...6,624,012
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19810
    role 19759
      biological role 19759
        antimicrobial agent 17402
          antifungal agent 15101
            antibiotic antifungal agent 1886
              echinocandin 1
                acrophiarin 0
                aminocandin 0
                anidulafungin 0
                caspofungin + 1
                cilofungin 0
                echinocandin B 0
                micafungin 0
                pneumocandin B0 + 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19809
      composite particle 19809
        hadron 19809
          baryon 19809
            nucleon 19809
              atomic nucleus 19809
                atom 19809
                  main group element atom 19706
                    p-block element atom 19706
                      carbon group element atom 19628
                        carbon atom 19618
                          organic molecular entity 19618
                            organic group 18728
                              organic divalent group 18719
                                organodiyl group 18719
                                  carbonyl group 18668
                                    carbonyl compound 18668
                                      carboxylic acid 18365
                                        carboacyl group 17484
                                          univalent carboacyl group 17484
                                            carbamoyl group 17300
                                              carboxamide 17300
                                                peptide 9445
                                                  lipopeptide 75
                                                    echinocandin 1
                                                      acrophiarin 0
                                                      aminocandin 0
                                                      anidulafungin 0
                                                      caspofungin + 1
                                                      cilofungin 0
                                                      echinocandin B 0
                                                      micafungin 0
                                                      pneumocandin B0 + 1
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