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ONTOLOGY REPORT - ANNOTATIONS


Term:hexachlorophene
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Accession:CHEBI:5693 term browser browse the term
Definition:An organochlorine compound that is diphenylmethane in which each of the phenyl groups is substituted by chlorines at positions 2, 3, and 5, and by a hydroxy group at position 6. An antiseptic that is effective against Gram-positive organisms, it is used in soaps and creams for the treatment of various skin disorders. It is also used in agriculture as an acaricide and fungicide, but is not approved for such use within the European Union.
Synonyms:exact_synonym: 2,2'-methylenebis(3,4,6-trichlorophenol)
 related_synonym: 2,2',3,3',5,5'-hexachloro-6,6'-dihydroxydiphenylmethane;   2,2'-dihydroxy-3,3',5,5',6,6'-hexachlorodiphenylmethane;   2,2'-methanediylbis(3,4,6-trichlorophenol);   Acigena;   Almederm;   Armohex;   Distodin;   Esaclorofene;   Exofene;   Formula=C13H6Cl6O2;   Gamophen;   Gamophene;   Germa-medica;   Hexa-Germ;   Hexabalm;   Hexafen;   Hexascrub;   Hexide;   InChI=1S/C13H6Cl6O2/c14-6-2-8(16)12(20)4(10(6)18)1-5-11(19)7(15)3-9(17)13(5)21/h2-3,20-21H,1H2;   InChIKey=ACGUYXCXAPNIKK-UHFFFAOYSA-N;   Nabac;   Phiso-Scrub;   Phisodan;   SMILES=Oc1c(Cl)cc(Cl)c(Cl)c1Cc1c(O)c(Cl)cc(Cl)c1Cl;   Septi-Soft;   Septisol;   Septofen;   Solu-Heks;   Soy-Dome;   Staphene O;   Ster-Zac;   Steral;   Steraskin;   Surgi-Cen;   Surgi-cin;   Surofene;   Tersaseptic;   Turgex;   bis(2-hydroxy-3,5,6-trichlorophenyl)methane;   bis(3,5,6-trichloro-2-hydroxyphenyl)methane;   hexachlorophenum;   hexaclorofeno
 xref: CAS:70-30-4 "ChemIDplus";   CAS:70-30-4 "KEGG COMPOUND";   CAS:70-30-4 "NIST Chemistry WebBook";   DrugBank:DB00756;   Drug_Central:1364 "DrugCentral";   HMDB:HMDB0014894;   KEGG:C08039;   KEGG:D00859;   LINCS:LSM-6032
 xref_mesh: MESH:D006582
 xref: PDBeChem:H3P;   PMID:1133685 "Europe PMC";   PMID:22313968 "Europe PMC";   PMID:23251633 "Europe PMC";   PMID:397166 "Europe PMC";   PMID:894425 "Europe PMC";   PMID:952574 "Europe PMC";   PPDB:381;   Patent:US2250480;   Patent:US2435593;   Patent:US2812365;   Reaxys:2064407 "Reaxys";   Wikipedia:Hexachlorophene


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hexachlorophene term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:6480464
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:6480464
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit JBrowse link 3 176,533,182 176,547,965 RGD:6480464
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit JBrowse link 2 189,088,570 189,096,785 RGD:6480464
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:6480464
G Dlg4 discs large MAGUK scaffold protein 4 JBrowse link 10 56,625,845 56,655,543 RGD:6480464
G Dlx4 distal-less homeobox 4 JBrowse link 10 82,958,525 82,963,919 RGD:6480464
G Dmrt1 doublesex and mab-3 related transcription factor 1 JBrowse link 1 243,477,403 243,582,629 RGD:6480464
G Eomes eomesodermin JBrowse link 8 127,144,367 127,152,618 RGD:6480464
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:6480464
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 JBrowse link 20 1,955,344 1,984,907 RGD:6480464
G Gabbr2 gamma-aminobutyric acid type B receptor subunit 2 JBrowse link 5 62,276,100 62,621,737 RGD:6480464
G Gabra1 gamma-aminobutyric acid type A receptor alpha1 subunit JBrowse link 10 27,310,718 27,371,802 RGD:6480464
G Gabrb2 gamma-aminobutyric acid type A receptor beta 2 subunit JBrowse link 10 27,973,694 28,193,072 RGD:6480464
G Grin2d glutamate ionotropic receptor NMDA type subunit 2D JBrowse link 1 101,819,068 101,859,146 RGD:6480464
G Grm1 glutamate metabotropic receptor 1 JBrowse link 1 4,753,141 5,165,859 RGD:6480464
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:6480464
G Homer1 homer scaffold protein 1 JBrowse link 2 22,909,550 23,012,303 RGD:6480464
G Myc MYC proto-oncogene, bHLH transcription factor JBrowse link 7 102,586,313 102,591,240 RGD:6480464
G Pax6 paired box 6 JBrowse link 3 95,700,241 95,728,682 RGD:6480464
G Plcb4 phospholipase C, beta 4 JBrowse link 3 128,601,163 128,971,720 RGD:6480464
G Siah1 siah E3 ubiquitin protein ligase 1 JBrowse link 19 21,372,163 21,395,773 RGD:6480464
G Sox2 SRY-box transcription factor 2 JBrowse link 2 121,165,137 121,167,545 RGD:6480464
G Stx4 syntaxin 4 JBrowse link 1 199,287,384 199,295,606 RGD:6480464
G Wnt3a Wnt family member 3A JBrowse link 10 45,598,898 45,643,151 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19679
    role 19623
      application 19246
        pesticide 15810
          acaricide 8870
            hexachlorophene 25
Path 2
Term Annotations click to browse term
  CHEBI ontology 19679
    subatomic particle 19675
      composite particle 19675
        hadron 19675
          baryon 19675
            nucleon 19675
              atomic nucleus 19675
                atom 19675
                  main group element atom 19555
                    p-block element atom 19555
                      carbon group element atom 19438
                        carbon atom 19430
                          organic molecular entity 19430
                            organic molecule 19353
                              organic cyclic compound 19102
                                carbocyclic compound 17516
                                  benzenoid aromatic compound 17038
                                    benzenes 16752
                                      chlorobenzenes 12584
                                        trichlorobenzene 1515
                                          hexachlorophene 25
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.