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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:helveticoside
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Accession:CHEBI:5650 term browser browse the term
Definition:A cardenolide glycoside that consists of strophanthidin having a digitoxosyl group attached at position 3.
Synonyms:exact_synonym: 3beta-[(2,6-dideoxy-beta-D-ribo-hexopyranosyl)oxy]-5,14-dihydroxy-19-oxo-5beta-card-20(22)-enolide
 related_synonym: (3beta,5beta)-3-[(2,6-dideoxy-beta-D-ribo-hexopyranosyl)oxy]-5,14-dihydroxy-19-oxocard-20(22)-enolide;   Formula=C29H42O9;   InChI=1S/C29H42O9/c1-16-25(33)22(31)12-24(37-16)38-18-3-8-27(15-30)20-4-7-26(2)19(17-11-23(32)36-14-17)6-10-29(26,35)21(20)5-9-28(27,34)13-18/h11,15-16,18-22,24-25,31,33-35H,3-10,12-14H2,1-2H3/t16-,18+,19-,20+,21-,22+,24+,25-,26-,27+,28+,29+/m1/s1;   InChIKey=QBILRDAMJUPXCX-AGAUEGNUSA-N;   SMILES=[H][C@@]1(CC[C@]2(O)[C@]3([H])CC[C@]4(O)C[C@H](CC[C@]4(C=O)[C@@]3([H])CC[C@]12C)O[C@H]1C[C@H](O)[C@H](O)[C@@H](C)O1)C1=CC(=O)OC1;   Strophanthidin 3-O-beta-D-digitoxoside;   alleoside A;   deglucoerysimoside;   erysimin;   erysimotoxin;   strophanthidin 3beta-digitoxoside
 xref: AGR:IND20482072;   CAS:630-64-8;   KEGG:C08869;   KNApSAcK:C00003625
 xref_mesh: MESH:C007914
 xref: PMID:1368415;   PMID:13965884;   PMID:14028075;   PMID:14073570;   PMID:14181242;   PMID:15907623;   PMID:24288558;   PMID:26384484;   PMID:32147288;   PMID:33180277;   PMID:33417512;   PMID:34616724;   PMID:37410515;   PMID:4237043;   PMID:4237044;   PMID:4679055


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helveticoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rorc RAR-related orphan receptor C increases expression ISO helveticoside results in increased expression of RORC mRNA CTD PMID:29981919 NCBI chr 2:182,009,707...182,034,910
Ensembl chr 2:182,009,286...182,034,907 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19899
    role 19869
      biological role 19867
        biochemical role 19574
          apoptosis inducer 13672
            helveticoside 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19899
    subatomic particle 19897
      composite particle 19897
        hadron 19897
          baryon 19897
            nucleon 19897
              atomic nucleus 19897
                atom 19897
                  main group element atom 19835
                    p-block element atom 19835
                      carbon group element atom 19776
                        carbon atom 19772
                          organic molecular entity 19772
                            heteroorganic entity 19532
                              organochalcogen compound 19293
                                organooxygen compound 19209
                                  carbon oxoacid 18678
                                    carboxylic acid 18675
                                      carboacyl group 17725
                                        univalent carboacyl group 17725
                                          formyl group 9058
                                            aldehyde 9058
                                              steroid aldehyde 92
                                                strophanthidin 6
                                                  helveticoside 1
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