The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
A sesquiterpene lactone that is 3,3a,4,4a,7a,8,9,9a-octahydroazuleno[6,5-b]furan-2,5-dione substituted by a hydroxy group at position 4, methyl groups at positions 4a and 8 and a methylidene group at position 3 (the 3aS,4S,4aR,7aR,8R,9aR stereoisomer).
helenalin inhibits the reaction [Drugs, Chinese Herbal results in increased expression of CD40 protein]; helenalin inhibits the reaction [Polysaccharides results in increased expression of CD40 protein]
helenalin inhibits the reaction [Drugs, Chinese Herbal results in increased expression of CD80 protein]; helenalin inhibits the reaction [Polysaccharides results in increased expression of CD80 protein]
helenalin inhibits the reaction [Drugs, Chinese Herbal results in increased expression of CD83 protein]; helenalin inhibits the reaction [Polysaccharides results in increased expression of CD83 protein]
helenalin inhibits the reaction [Drugs, Chinese Herbal results in increased expression of CD86 protein]; helenalin inhibits the reaction [Polysaccharides results in increased expression of CD86 protein]
helenalin inhibits the reaction [Drugs, Chinese Herbal results in increased expression of ICAM1 protein]; helenalin inhibits the reaction [Polysaccharides results in increased expression of ICAM1 protein] helenalin inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; helenalin inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]
helenalin inhibits the reaction [Drugs, Chinese Herbal results in increased secretion of IL10 protein]; helenalin inhibits the reaction [Polysaccharides results in increased secretion of IL10 protein]
helenalin inhibits the reaction [Drugs, Chinese Herbal results in increased secretion of [IL12A protein binds to IL12B protein]]; helenalin inhibits the reaction [Polysaccharides results in increased secretion of [IL12A protein binds to IL12B protein]]
helenalin inhibits the reaction [Drugs, Chinese Herbal results in increased secretion of [IL12A protein binds to IL12B protein]]; helenalin inhibits the reaction [Drugs, Chinese Herbal results in increased secretion of IL12B protein]; helenalin inhibits the reaction [Polysaccharides results in increased secretion of [IL12A protein binds to IL12B protein]]; helenalin inhibits the reaction [Polysaccharides results in increased secretion of IL12B protein]
helenalin inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA]; helenalin inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA]; helenalin inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]; helenalin inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]
helenalin inhibits the reaction [CD 437 results in decreased expression of NFKBIA protein] helenalin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]
helenalin inhibits the reaction [Particulate Matter results in increased expression of PTGS2 mRNA]; helenalin inhibits the reaction [Particulate Matter results in increased expression of PTGS2 protein] helenalin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]
helenalin inhibits the reaction [Acetylmuramyl-Alanyl-Isoglutamine results in increased activity of RELA protein]; helenalin inhibits the reaction [CD 437 results in increased localization of RELA protein]; helenalin inhibits the reaction [Particulate Matter results in increased phosphorylation of RELA protein] helenalin results in decreased activity of RELA protein helenalin inhibits the reaction [TNF protein results in increased phosphorylation of RELA protein]
helenalin inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; helenalin inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; helenalin inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]; helenalin inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]; helenalin inhibits the reaction [TNF protein results in increased phosphorylation of RELA protein]
helenalin inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]; helenalin inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]
helenalin inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]; helenalin inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]