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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:guanadrel sulfate
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Accession:CHEBI:5556 term browser browse the term
Definition:An organic sulfate salt resulting from the reaction of 2 eq. guanadrel with 1 eq. sulfuric acid. A postganglionic adrenergic blocking agent formerly used for the management of hypertension, it has been largely superseded by other drugs less likely to cause orthostatic hypotension (dizzy spells on standing up or stretching).
Synonyms:exact_synonym: 1-(1,4-dioxaspiro[4.5]dec-2-ylmethyl)guanidine sulfate
 related_synonym: Anarel;   CL-1388R;   Formula=C20H40N6O8S;   Hylorel;   InChI=1S/2C10H19N3O2.H2O4S/c2*11-9(12)13-6-8-7-14-10(15-8)4-2-1-3-5-10;1-5(2,3)4/h2*8H,1-7H2,(H4,11,12,13);(H2,1,2,3,4);   InChIKey=RTEVGQJRTFFMLL-UHFFFAOYSA-N;   SMILES=OS(O)(=O)=O.NC(=N)NCC1COC2(CCCCC2)O1.NC(=N)NCC1COC2(CCCCC2)O1;   U 28288D;   U-28,288D;   bis{amino[(1,4-dioxaspiro[4.5]dec-2-ylmethyl)amino]methaniminium} sulfate
 xref: CAS:22195-34-2;   DrugBank:DBSALT000889;   KEGG:D00607;   PMID:2000792;   PMID:4984036;   PMID:4984037;   PMID:6351026;   PMID:6621504;   PMID:6762533;   Reaxys:13410559


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Path 1
Term Annotations click to browse term
  CHEBI ontology 26034
    role 25961
      application 25172
        pharmaceutical 24558
          drug 24544
            cardiovascular drug 8765
              antihypertensive agent 2020
                guanadrel sulfate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 26034
    subatomic particle 26009
      composite particle 26009
        hadron 26020
          baryon 26009
            nucleon 26009
              atomic nucleus 26009
                atom 26009
                  main group element atom 25834
                    p-block element atom 25834
                      chalcogen 24917
                        oxygen atom 24817
                          oxygen molecular entity 24806
                            hydroxides 24049
                              oxoacid 22975
                                chalcogen oxoacid 14506
                                  sulfur oxoacid 14255
                                    sulfuric acid 8713
                                      sulfuric acid derivative 8713
                                        sulfates 8708
                                          sulfate salt 7561
                                            organic sulfate salt 226
                                              guanadrel sulfate 0
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