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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:(2R,3S)-2-hydroxy-3-methylpentanoic acid
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Accession:CHEBI:55536 term browser browse the term
Definition:A valeric acid derivative having an (R)-hydroxy substituent at the 2-position and an (S)-methyl substituent at the 3-position; one of 4 steroisomers of 2-hydroxy-3-methylpentanoic acid, generated by isoleucine metabolism. Found at significantly higher levels than normal in patients with maple syrup urine disease (MSUD).
Synonyms:related_synonym: (2R,3S)-2-hydroxy-3-methylvaleric acid;   (2R,3S)-HMVA;   (2R,3S)-isoleucic acid;   (R,S)-isoleucic acid;   Formula=C6H12O3;   HMVA;   InChI=1S/C6H12O3/c1-3-4(2)5(7)6(8)9/h4-5,7H,3H2,1-2H3,(H,8,9)/t4-,5+/m0/s1;   InChIKey=RILPIWOPNGRASR-CRCLSJGQSA-N;   SMILES=CC[C@H](C)[C@@H](O)C(O)=O
 xref: Beilstein:1721800;   PMID:1429566
 cyclic_relationship: is_conjugate_acid_of CHEBI:55537

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  CHEBI ontology 0
    role 0
      biological role 0
        biochemical role 0
          metabolite 0
            eukaryotic metabolite 0
              plant metabolite 0
                valeric acid 0
                  (2R,3S)-2-hydroxy-3-methylpentanoic acid 0
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  CHEBI ontology 0
    subatomic particle 0
      composite particle 0
        hadron 0
          baryon 0
            nucleon 0
              atomic nucleus 0
                atom 0
                  main group element atom 0
                    p-block element atom 0
                      carbon group element atom 0
                        carbon atom 0
                          organic molecular entity 0
                            heteroorganic entity 0
                              organochalcogen compound 0
                                organooxygen compound 0
                                  carbon oxoacid 0
                                    carboxylic acid 0
                                      monocarboxylic acid 0
                                        fatty acid 0
                                          hydroxy fatty acid 0
                                            2-hydroxy fatty acid 0
                                              2-hydroxy-3-methylpentanoic acid 0
                                                (2R,3S)-2-hydroxy-3-methylpentanoic acid 0
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