CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: trichothecene
Accession: CHEBI:55517
browse the term
Definition: Any one of a large family of chemically related mycotoxins with a structure based on a sesquiterpene skeleton. The most important structural features causing the biological activities of trichothecenes are a 12,13-epoxy ring, the presence of hydroxy or acetyl groups at appropriate positions on the trichothecene nucleus and the structure and position of the side-chain.
Synonyms: related_synonym: Formula=C15H17O2R5; SMILES=[H][C@]12O[C@]3([H])[C@H]([*])[C@@H]([*])[C@@](C)(C33CO3)C1(C[*])C([*])C([*])C(C)=C2; trichothecenes
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Adrb2
adrenoceptor beta 2
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of ADRB2 mRNA
CTD
PMID:23792671
NCBI chr18:57,912,760...57,914,802
Ensembl chr18:57,911,348...57,914,803
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Angptl4
angiopoietin-like 4
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of ANGPTL4 mRNA
CTD
PMID:23792671
NCBI chr 7:15,252,450...15,259,971
Ensembl chr 7:15,252,473...15,258,681
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Ar
androgen receptor
decreases activity multiple interactions
ISO
15-acetyldeoxynivalenol results in decreased activity of AR protein [15-acetyldeoxynivalenol co-treated with 3-acetyldeoxynivalenol co-treated with deoxynivalenol co-treated with zearalenol co-treated with Zearalenone] results in decreased activity of AR protein; [15-acetyldeoxynivalenol co-treated with 3-acetyldeoxynivalenol co-treated with deoxynivalenol] results in decreased activity of AR protein
CTD
PMID:27481073
NCBI chr X:67,135,317...67,304,476
Ensembl chr X:67,135,317...67,304,467
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Arc
activity-regulated cytoskeleton-associated protein
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of ARC mRNA
CTD
PMID:23792671
NCBI chr 7:108,444,959...108,448,413
Ensembl chr 7:108,444,692...108,451,220
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Areg
amphiregulin
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of AREG mRNA
CTD
PMID:23792671
NCBI chr14:17,256,384...17,265,641
Ensembl chr14:17,256,384...17,265,641
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Arid5a
AT-rich interaction domain 5A
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of ARID5A mRNA
CTD
PMID:23792671
NCBI chr 9:46,030,513...46,058,729
Ensembl chr 9:46,030,548...46,045,363
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Arl5b
ARF like GTPase 5B
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of ARL5B mRNA
CTD
PMID:23792671
NCBI chr17:82,864,315...82,888,458
Ensembl chr17:82,864,287...82,890,646
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Arrdc4
arrestin domain containing 4
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of ARRDC4 mRNA
CTD
PMID:23792671
NCBI chr 1:131,779,436...131,793,438
Ensembl chr 1:131,779,437...131,793,565
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Atf3
activating transcription factor 3
increases expression multiple interactions
ISO
15-acetyldeoxynivalenol results in increased expression of ATF3 mRNA [Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] promotes the reaction [15-acetyldeoxynivalenol results in increased expression of ATF3 mRNA]
CTD
PMID:19101521 PMID:22003189 PMID:23792671
NCBI chr13:105,274,103...105,331,653
Ensembl chr13:105,282,440...105,295,750
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Atf6
activating transcription factor 6
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of ATF6 mRNA
CTD
PMID:20682335
NCBI chr13:85,460,312...85,639,959
Ensembl chr13:85,462,840...85,640,033
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Atosb
atos homolog B
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of ATOSB mRNA
CTD
PMID:23792671
NCBI chr 5:62,056,654...62,070,338
Ensembl chr 5:62,056,654...62,064,613
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Bdkrb1
bradykinin receptor B1
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of BDKRB1 mRNA
CTD
PMID:23792671
NCBI chr 6:130,275,631...130,284,968
Ensembl chr 6:130,275,478...130,280,973
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Bdkrb2
bradykinin receptor B2
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of BDKRB2 mRNA
CTD
PMID:23792671
NCBI chr 6:130,237,055...130,267,205
Ensembl chr 6:130,237,255...130,267,209
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Bhlhe40
basic helix-loop-helix family, member e40
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of BHLHE40 mRNA
CTD
PMID:23792671
NCBI chr 4:143,174,450...143,180,150
Ensembl chr 4:143,174,048...143,180,783
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Btg2
BTG anti-proliferation factor 2
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of BTG2 mRNA
CTD
PMID:23792671
NCBI chr13:48,083,931...48,087,690
Ensembl chr13:48,083,931...48,087,690
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C3h11orf96
similar to human chromosome 11 open reading frame 96
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of C11ORF96 mRNA
CTD
PMID:23792671
NCBI chr 3:100,375,474...100,376,717
Ensembl chr 3:100,351,199...100,378,346
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Ccdc116
coiled-coil domain containing 116
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of CCDC116 mRNA
CTD
PMID:23792671
NCBI chr11:97,346,927...97,354,827
Ensembl chr11:97,346,675...97,354,824
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Cck
cholecystokinin
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of CCK protein
CTD
PMID:24385417
NCBI chr 8:130,031,012...130,037,702
Ensembl chr 8:130,031,013...130,037,686
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Ccl2
C-C motif chemokine ligand 2
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of CCL2 mRNA
CTD
PMID:24793808
NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875
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Ccl3
C-C motif chemokine ligand 3
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of CCL3 mRNA
CTD
PMID:23792671
NCBI chr10:68,948,889...68,950,439
Ensembl chr10:68,948,889...68,950,439
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Ccl4
C-C motif chemokine ligand 4
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of CCL4 mRNA
CTD
PMID:23792671
NCBI chr10:68,963,893...68,965,728
Ensembl chr10:68,950,289...68,965,722
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Ccl7
C-C motif chemokine ligand 7
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of CCL7 mRNA
CTD
PMID:24793808
NCBI chr10:67,514,095...67,515,945
Ensembl chr10:67,514,091...67,515,947
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Ccr7
C-C motif chemokine receptor 7
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of CCR7 mRNA
CTD
PMID:23792671
NCBI chr10:84,594,399...84,604,514
Ensembl chr10:84,593,594...84,604,501
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Crem
cAMP responsive element modulator
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of CREM mRNA
CTD
PMID:23792671
NCBI chr17:58,932,011...59,001,160
Ensembl chr17:58,934,147...59,001,160
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Cxcl2
C-X-C motif chemokine ligand 2
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of CXCL2 mRNA
CTD
PMID:24793808
NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,465,242...17,467,255
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Cxcr4
C-X-C motif chemokine receptor 4
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of CXCR4 mRNA
CTD
PMID:23792671
NCBI chr13:42,630,383...42,634,288
Ensembl chr13:42,630,104...42,634,459
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Ddit3
DNA-damage inducible transcript 3
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of DDIT3 mRNA
CTD
PMID:23792671
NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509
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Dixdc1
DIX domain containing 1
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of DIXDC1 mRNA
CTD
PMID:23792671
NCBI chr 8:59,904,218...59,977,595
Ensembl chr 8:59,904,218...59,978,447
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Dlx1
distal-less homeobox 1
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of DLX1 mRNA
CTD
PMID:23792671
NCBI chr 3:76,763,864...76,768,454
Ensembl chr 3:76,763,500...76,768,447
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Dlx2
distal-less homeobox 2
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of DLX2 mRNA
CTD
PMID:23792671
NCBI chr 3:76,777,912...76,781,255
Ensembl chr 3:76,777,912...76,781,255
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Dmrt2
doublesex and mab-3 related transcription factor 2
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of DMRT2 mRNA
CTD
PMID:23792671
NCBI chr 1:232,743,935...232,750,431
Ensembl chr 1:232,743,942...232,750,431
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Dnajb5
DnaJ heat shock protein family (Hsp40) member B5
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of DNAJB5 mRNA
CTD
PMID:23792671
NCBI chr 5:61,972,637...61,981,887
Ensembl chr 5:61,972,706...61,981,860
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Dusp10
dual specificity phosphatase 10
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of DUSP10 mRNA
CTD
PMID:23792671
NCBI chr13:98,145,317...98,183,304
Ensembl chr13:98,145,893...98,183,304
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Dusp8
dual specificity phosphatase 8
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of DUSP8 mRNA
CTD
PMID:23792671
NCBI chr 1:206,596,912...206,613,728
Ensembl chr 1:206,598,942...206,612,441
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Egr3
early growth response 3
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of EGR3 mRNA
CTD
PMID:23792671
NCBI chr15:51,560,482...51,565,778
Ensembl chr15:51,560,344...51,565,712
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Eif2a
eukaryotic translation initiation factor 2A
increases phosphorylation
ISO
15-acetyldeoxynivalenol results in increased phosphorylation of EIF2A protein
CTD
PMID:20682335
NCBI chr 2:144,911,247...144,944,705
Ensembl chr 2:144,911,153...144,945,201
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Emx2
empty spiracles homeobox 2
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of EMX2 mRNA
CTD
PMID:23792671
NCBI chr 1:268,612,663...268,619,671
Ensembl chr 1:268,612,663...268,619,671
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Ephb3
Eph receptor B3
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of EPHB3 mRNA
CTD
PMID:23792671
NCBI chr11:93,345,098...93,363,775
Ensembl chr11:93,345,098...93,363,775
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Ereg
epiregulin
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of EREG mRNA
CTD
PMID:23792671
NCBI chr14:17,311,485...17,325,260
Ensembl chr14:17,311,485...17,325,260
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Ern1
endoplasmic reticulum to nucleus signaling 1
decreases expression
ISO
15-acetyldeoxynivalenol results in decreased expression of ERN1 mRNA
CTD
PMID:20682335
NCBI chr10:91,826,663...91,920,976
Ensembl chr10:91,830,428...91,920,791
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Fam43a
family with sequence similarity 43, member A
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of FAM43A mRNA
CTD
PMID:23792671
NCBI chr11:83,633,165...83,636,313
Ensembl chr11:83,633,154...83,695,297
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Fbp2
fructose-bisphosphatase 2
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of FBP2 mRNA
CTD
PMID:23792671
NCBI chr17:2,241,767...2,259,371
Ensembl chr17:2,241,975...2,259,366
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Fgf9
fibroblast growth factor 9
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of FGF9 mRNA
CTD
PMID:23792671
NCBI chr15:36,325,552...36,369,995
Ensembl chr15:36,325,599...36,367,926
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Fjx1
four-jointed box kinase 1
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of FJX1 mRNA
CTD
PMID:23792671
NCBI chr 3:109,229,223...109,231,324
Ensembl chr 3:109,227,170...109,232,479
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Gem
GTP binding protein overexpressed in skeletal muscle
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of GEM mRNA
CTD
PMID:23792671
NCBI chr 5:30,011,641...30,022,554
Ensembl chr 5:30,011,592...30,022,542
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Gfod1
Gfo/Idh/MocA-like oxidoreductase domain containing 1
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of GFOD1 mRNA
CTD
PMID:23792671
NCBI chr17:21,606,090...21,710,922
Ensembl chr17:21,605,415...21,710,920
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Gtf2ird2
GTF2I repeat domain containing 2
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of GTF2IRD2 mRNA
CTD
PMID:23792671
NCBI chr12:28,134,199...28,179,089
Ensembl chr12:28,133,792...28,172,876
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Has2
hyaluronan synthase 2
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of HAS2 mRNA
CTD
PMID:23792671
NCBI chr 7:90,002,929...90,028,933
Ensembl chr 7:90,002,929...90,018,535
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Hoxb2
homeobox B2
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of HOXB2 mRNA
CTD
PMID:23792671
NCBI chr10:81,814,340...81,816,731
Ensembl chr10:81,814,340...81,816,726
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Hpse2
heparanase 2 (inactive)
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of HPSE2 mRNA
CTD
PMID:23792671
NCBI chr 1:251,532,149...252,231,316
Ensembl chr 1:251,532,149...252,195,255
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Hspa5
heat shock protein family A (Hsp70) member 5
decreases expression
ISO
15-acetyldeoxynivalenol results in decreased expression of HSPA5 mRNA
CTD
PMID:20682335
NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790
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Il10ra
interleukin 10 receptor subunit alpha
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of IL10RA mRNA
CTD
PMID:23792671
NCBI chr 8:54,459,754...54,474,786
Ensembl chr 8:54,459,882...54,475,028
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Il1b
interleukin 1 beta
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of IL1B mRNA
CTD
PMID:23792671 PMID:24793808
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
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Il2
interleukin 2
affects secretion increases expression
ISO
15-acetyldeoxynivalenol affects the secretion of IL2 protein 15-acetyldeoxynivalenol results in increased expression of IL2 mRNA
CTD
PMID:8560498
NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672
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Il4
interleukin 4
affects secretion
ISO
15-acetyldeoxynivalenol affects the secretion of IL4 protein
CTD
PMID:8560498
NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549
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Il5
interleukin 5
affects secretion
ISO
15-acetyldeoxynivalenol affects the secretion of IL5 protein
CTD
PMID:8560498
NCBI chr10:38,375,132...38,378,003
Ensembl chr10:38,375,132...38,378,003
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Il6
interleukin 6
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of IL6 mRNA
CTD
PMID:8560498 PMID:24793808
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
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Iqcn
IQ motif containing N
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of IQCN mRNA
CTD
PMID:23792671
NCBI chr16:18,750,492...18,766,184
Ensembl chr16:18,750,353...18,767,534
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Irgm
immunity-related GTPase M
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of IRGM mRNA
CTD
PMID:23792671
NCBI chr10:33,734,640...33,742,720
Ensembl chr10:33,732,961...33,743,228
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Kcnj2
potassium inwardly-rectifying channel, subfamily J, member 2
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of KCNJ2 mRNA
CTD
PMID:23792671
NCBI chr10:96,560,225...96,570,788
Ensembl chr10:96,565,600...96,570,901
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Klf10
KLF transcription factor 10
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of KLF10 mRNA
CTD
PMID:23792671
NCBI chr 7:71,352,612...71,358,680
Ensembl chr 7:71,350,573...71,358,948
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Man1b1
mannosidase, alpha, class 1B, member 1
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of MAN1B1 mRNA
CTD
PMID:23792671
NCBI chr 3:28,539,778...28,563,155
Ensembl chr 3:28,541,347...28,563,154
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Mfsd2a
MFSD2 lysolipid transporter A, lysophospholipid
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of MFSD2A mRNA
CTD
PMID:23792671
NCBI chr 5:140,510,933...140,525,828
Ensembl chr 5:140,510,953...140,525,916
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Mras
muscle RAS oncogene homolog
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of MRAS mRNA
CTD
PMID:23792671
NCBI chr 8:108,823,374...108,886,104
Ensembl chr 8:108,823,374...108,875,911
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Mroh3
maestro heat-like repeat family member 3
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of MROH3P mRNA
CTD
PMID:23792671
NCBI chr13:50,181,713...50,217,164
Ensembl chr13:50,181,713...50,217,164
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Mxd1
max dimerization protein 1
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of MXD1 mRNA
CTD
PMID:23792671
NCBI chr 4:120,654,731...120,678,972
Ensembl chr 4:120,654,731...120,675,129
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Neurl3
neuralized E3 ubiquitin protein ligase 3
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of NEURL3 mRNA
CTD
PMID:23792671
NCBI chr 9:45,990,373...45,998,470
Ensembl chr 9:45,990,375...45,998,535
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Nod2
nucleotide-binding oligomerization domain containing 2
multiple interactions
ISO
[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] promotes the reaction [15-acetyldeoxynivalenol results in increased expression of ATF3 mRNA]
CTD
PMID:22003189
NCBI chr19:34,555,832...34,596,281
Ensembl chr19:34,555,832...34,722,846
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Nr4a3
nuclear receptor subfamily 4, group A, member 3
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of NR4A3 mRNA
CTD
PMID:23792671
NCBI chr 5:67,157,141...67,198,287
Ensembl chr 5:67,157,375...67,198,285
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Nwd2
NACHT and WD repeat domain containing 2
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of NWD2 mRNA
CTD
PMID:23792671
NCBI chr14:44,833,623...45,024,962
Ensembl chr14:44,834,856...45,024,047
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Pcdh9
protocadherin 9
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of PCDH9 mRNA
CTD
PMID:23792671
NCBI chr15:75,748,472...76,646,644 NCBI chr15:76,078,024...76,127,778
Ensembl chr15:75,749,278...76,645,302
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Per1
period circadian regulator 1
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of PER1 mRNA
CTD
PMID:23792671
NCBI chr10:54,299,002...54,313,804
Ensembl chr10:54,302,641...54,314,211
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Pparg
peroxisome proliferator-activated receptor gamma
decreases activity
ISO
15-acetyldeoxynivalenol results in decreased activity of PPARG protein
CTD
PMID:27481073
NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104
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Ptgs2
prostaglandin-endoperoxide synthase 2
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of PTGS2 mRNA
CTD
PMID:14514436
NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
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Rcan1
regulator of calcineurin 1
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of RCAN1 mRNA
CTD
PMID:23792671
NCBI chr11:45,108,123...45,188,065
Ensembl chr11:45,108,124...45,118,236
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Rem2
RRAD and GEM like GTPase 2
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of REM2 mRNA
CTD
PMID:23792671
NCBI chr15:31,903,972...31,908,451
Ensembl chr15:31,903,965...31,908,445
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Rgs16
regulator of G-protein signaling 16
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of RGS16 mRNA
CTD
PMID:23792671
NCBI chr13:68,421,480...68,443,312
Ensembl chr13:68,438,120...68,443,313
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Rhoh
ras homolog family member H
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of RHOH mRNA
CTD
PMID:23792671
NCBI chr14:42,694,860...42,725,690
Ensembl chr14:42,693,413...42,749,967
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Rnd1
Rho family GTPase 1
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of RND1 mRNA
CTD
PMID:23792671
NCBI chr 7:131,700,321...131,707,392
Ensembl chr 7:131,700,321...131,707,392
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Six1
SIX homeobox 1
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of SIX1 mRNA
CTD
PMID:23792671
NCBI chr 6:97,482,617...97,487,853
Ensembl chr 6:97,482,617...97,487,853
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Slc34a1
solute carrier family 34 member 1
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of SLC34A1 mRNA
CTD
PMID:23792671
NCBI chr17:9,224,010...9,238,983
Ensembl chr17:9,224,010...9,238,983
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Stmn4
stathmin 4
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of STMN4 mRNA
CTD
PMID:23792671
NCBI chr15:44,716,825...44,734,776
Ensembl chr15:44,716,880...44,742,086
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Stox2
storkhead box 2
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of STOX2 mRNA
CTD
PMID:23792671
NCBI chr16:51,580,855...51,819,909
Ensembl chr16:51,580,798...51,815,209
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Tfap2a
transcription factor AP-2 alpha
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of TFAP2A mRNA
CTD
PMID:23792671
NCBI chr17:24,230,064...24,253,219
Ensembl chr17:24,229,910...24,253,219
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Thrb
thyroid hormone receptor beta
multiple interactions
ISO
[15-acetyldeoxynivalenol co-treated with 3-acetyldeoxynivalenol co-treated with deoxynivalenol co-treated with zearalenol co-treated with Zearalenone] results in decreased activity of THRB protein
CTD
PMID:27481073
NCBI chr15:10,115,954...10,465,231
Ensembl chr15:10,115,954...10,313,680
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Tmcc2
transmembrane and coiled-coil domain family 2
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of TMCC2 mRNA
CTD
PMID:23792671
NCBI chr13:46,346,177...46,383,862
Ensembl chr13:46,346,177...46,383,862
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Tmem88
transmembrane protein 88
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of TMEM88 mRNA
CTD
PMID:23792671
NCBI chr10:54,617,554...54,619,309
Ensembl chr10:54,617,630...54,619,438
G
Tnf
tumor necrosis factor
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of TNF mRNA
CTD
PMID:23792671 PMID:24793808
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
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Ucp1
uncoupling protein 1
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of UCP1 mRNA
CTD
PMID:23792671
NCBI chr19:41,713,350...41,721,421
Ensembl chr19:41,713,351...41,721,420
G
Zbtb21
zinc finger and BTB domain containing 21
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of ZBTB21 mRNA
CTD
PMID:23792671
NCBI chr11:50,781,697...50,796,399
Ensembl chr11:50,781,099...50,796,560
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Zc3h12d
zinc finger CCCH type containing 12D
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of ZC3H12D mRNA
CTD
PMID:23792671
NCBI chr 1:4,131,674...4,169,192
Ensembl chr 1:4,134,697...4,169,191
G
Zfp2
zinc finger protein 2
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of ZFP2 mRNA
CTD
PMID:23792671
NCBI chr10:35,701,303...35,729,861
Ensembl chr10:35,702,151...35,730,108
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Zfp77
zinc finger protein 77
increases expression
ISO
15-acetyldeoxynivalenol results in increased expression of ZNF77 mRNA
CTD
PMID:23792671
NCBI chr 7:7,920,674...7,967,079
Ensembl chr 7:7,920,716...7,937,127
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Ar
androgen receptor
decreases activity multiple interactions
ISO
3-acetyldeoxynivalenol results in decreased activity of AR protein [15-acetyldeoxynivalenol co-treated with 3-acetyldeoxynivalenol co-treated with deoxynivalenol co-treated with zearalenol co-treated with Zearalenone] results in decreased activity of AR protein; [15-acetyldeoxynivalenol co-treated with 3-acetyldeoxynivalenol co-treated with deoxynivalenol] results in decreased activity of AR protein
CTD
PMID:27481073
NCBI chr X:67,135,317...67,304,476
Ensembl chr X:67,135,317...67,304,467
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Atf4
activating transcription factor 4
increases expression multiple interactions
ISO
3-acetyldeoxynivalenol results in increased expression of ATF4 mRNA 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of ATF4 mRNA]
CTD
PMID:35413383
NCBI chr 7:113,684,681...113,686,739
Ensembl chr 7:113,684,681...113,686,739
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Atf6
activating transcription factor 6
increases expression multiple interactions
ISO
3-acetyldeoxynivalenol results in increased expression of ATF6 mRNA 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of ATF6 mRNA]
CTD
PMID:20682335 PMID:35413383
NCBI chr13:85,460,312...85,639,959
Ensembl chr13:85,462,840...85,640,033
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Cck
cholecystokinin
increases expression
ISO
3-acetyldeoxynivalenol results in increased expression of CCK protein
CTD
PMID:24385417
NCBI chr 8:130,031,012...130,037,702
Ensembl chr 8:130,031,013...130,037,686
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Ccl2
C-C motif chemokine ligand 2
increases expression multiple interactions
ISO
3-acetyldeoxynivalenol results in increased expression of CCL2 mRNA 3-acetyldeoxynivalenol results in increased expression of and results in increased secretion of CCL2 protein; 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of and results in increased secretion of CCL2 protein]; 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of CCL2 mRNA]
CTD
PMID:24793808 PMID:35413383
NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875
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Ccl7
C-C motif chemokine ligand 7
increases expression
ISO
3-acetyldeoxynivalenol results in increased expression of CCL7 mRNA
CTD
PMID:24793808
NCBI chr10:67,514,095...67,515,945
Ensembl chr10:67,514,091...67,515,947
G
Csf1
colony stimulating factor 1
increases expression multiple interactions
ISO
3-acetyldeoxynivalenol results in increased expression of CSF1 mRNA 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of CSF1 mRNA]
CTD
PMID:35413383
NCBI chr 2:198,065,400...198,084,774
Ensembl chr 2:198,065,405...198,084,468
G
Csf2
colony stimulating factor 2
multiple interactions
ISO
3-acetyldeoxynivalenol results in increased expression of and results in increased secretion of CSF2 protein; 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of and results in increased secretion of CSF2 protein]
CTD
PMID:35413383
NCBI chr10:38,887,692...38,889,673
Ensembl chr10:38,887,692...38,890,031
G
Csf3
colony stimulating factor 3
multiple interactions increases expression
ISO
4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of CSF3 mRNA]
CTD
PMID:35413383
NCBI chr10:84,157,485...84,159,860
Ensembl chr10:84,157,211...84,159,860
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Cxcl2
C-X-C motif chemokine ligand 2
increases expression
ISO
3-acetyldeoxynivalenol results in increased expression of CXCL2 mRNA
CTD
PMID:24793808
NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,465,242...17,467,255
G
Ddit3
DNA-damage inducible transcript 3
multiple interactions increases expression
ISO
4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of DDIT3 mRNA]
CTD
PMID:35413383
NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509
G
Eif2a
eukaryotic translation initiation factor 2A
increases phosphorylation
ISO
3-acetyldeoxynivalenol results in increased phosphorylation of EIF2A protein
CTD
PMID:20682335
NCBI chr 2:144,911,247...144,944,705
Ensembl chr 2:144,911,153...144,945,201
G
Eif2ak3
eukaryotic translation initiation factor 2 alpha kinase 3
increases expression
ISO
3-acetyldeoxynivalenol results in increased expression of EIF2AK3 mRNA
CTD
PMID:35413383
NCBI chr 4:104,363,838...104,425,271
Ensembl chr 4:104,363,833...104,425,268
G
Eif2s1
eukaryotic translation initiation factor 2 subunit alpha
increases expression multiple interactions
ISO
3-acetyldeoxynivalenol results in increased expression of EIF2S1 mRNA 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of EIF2S1 mRNA]
CTD
PMID:35413383
NCBI chr 6:103,405,880...103,430,549
Ensembl chr 6:103,405,788...103,431,649
G
Ern1
endoplasmic reticulum to nucleus signaling 1
increases expression multiple interactions
ISO
3-acetyldeoxynivalenol results in increased expression of ERN1 mRNA 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of ERN1 mRNA]
CTD
PMID:20682335 PMID:35413383
NCBI chr10:91,826,663...91,920,976
Ensembl chr10:91,830,428...91,920,791
G
Hspa5
heat shock protein family A (Hsp70) member 5
decreases expression increases expression multiple interactions
ISO
3-acetyldeoxynivalenol results in decreased expression of HSPA5 mRNA 3-acetyldeoxynivalenol results in increased expression of HSPA5 mRNA 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of HSPA5 mRNA]
CTD
PMID:20682335 PMID:35413383
NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790
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Ifnb1
interferon beta 1
increases expression multiple interactions
ISO
3-acetyldeoxynivalenol results in increased expression of IFNB1 mRNA 3-acetyldeoxynivalenol results in increased expression of and results in increased secretion of IFNB1 protein; 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of and results in increased secretion of IFNB1 protein]; 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of IFNB1 mRNA]
CTD
PMID:35413383
NCBI chr 5:108,066,650...108,067,487
Ensembl chr 5:108,066,650...108,067,487
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Ifng
interferon gamma
multiple interactions increases expression
ISO
4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of IFNG mRNA]
CTD
PMID:35413383
NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216
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Il10
interleukin 10
multiple interactions increases expression
ISO
3-acetyldeoxynivalenol results in increased expression of and results in increased secretion of IL10 protein; 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of and results in increased secretion of IL10 protein]; 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of IL10 mRNA]
CTD
PMID:35413383
NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580
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Il17a
interleukin 17A
increases expression multiple interactions
ISO
3-acetyldeoxynivalenol results in increased expression of IL17A mRNA 3-acetyldeoxynivalenol results in increased expression of and results in increased secretion of IL17A protein; 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of and results in increased secretion of IL17A protein]; 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of IL17A mRNA]
CTD
PMID:35413383
NCBI chr 9:30,640,844...30,644,331
Ensembl chr 9:30,640,844...30,644,331
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Il1a
interleukin 1 alpha
increases expression multiple interactions
ISO
3-acetyldeoxynivalenol results in increased expression of IL1A mRNA 3-acetyldeoxynivalenol results in increased expression of and results in increased secretion of IL1A protein; 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of and results in increased secretion of IL1A protein]; 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of IL1A mRNA]
CTD
PMID:35413383
NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013
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Il1b
interleukin 1 beta
increases expression multiple interactions
ISO
3-acetyldeoxynivalenol results in increased expression of IL1B mRNA 3-acetyldeoxynivalenol results in increased expression of and results in increased secretion of IL1B protein; 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of and results in increased secretion of IL1B protein]; 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of IL1B mRNA]
CTD
PMID:24793808 PMID:35413383
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
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Il2
interleukin 2
affects secretion increases expression
ISO
3-acetyldeoxynivalenol affects the secretion of IL2 protein 3-acetyldeoxynivalenol results in increased expression of IL2 mRNA
CTD
PMID:8560498
NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672
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Il4
interleukin 4
affects secretion
ISO
3-acetyldeoxynivalenol affects the secretion of IL4 protein
CTD
PMID:8560498
NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549
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Il5
interleukin 5
affects secretion
ISO
3-acetyldeoxynivalenol affects the secretion of IL5 protein
CTD
PMID:8560498
NCBI chr10:38,375,132...38,378,003
Ensembl chr10:38,375,132...38,378,003
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Il6
interleukin 6
increases expression multiple interactions
ISO
3-acetyldeoxynivalenol results in increased expression of IL6 mRNA 3-acetyldeoxynivalenol results in increased expression of and results in increased secretion of IL6 protein; 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of and results in increased secretion of IL6 protein]; 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of IL6 mRNA]
CTD
PMID:24793808 PMID:35413383
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
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Mapk8
mitogen-activated protein kinase 8
multiple interactions increases expression
ISO
4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of MAPK8 mRNA]
CTD
PMID:35413383
NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427
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Mpo
myeloperoxidase
multiple interactions increases secretion
ISO
4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased secretion of MPO protein]
CTD
PMID:35413383
NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056
G
Pparg
peroxisome proliferator-activated receptor gamma
decreases activity
ISO
3-acetyldeoxynivalenol results in decreased activity of PPARG protein
CTD
PMID:27481073
NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104
G
Ptgs2
prostaglandin-endoperoxide synthase 2
increases expression
ISO
3-acetyldeoxynivalenol results in increased expression of PTGS2 mRNA
CTD
PMID:14514436
NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
G
Thrb
thyroid hormone receptor beta
decreases activity multiple interactions
ISO
3-acetyldeoxynivalenol results in decreased activity of THRB protein [15-acetyldeoxynivalenol co-treated with 3-acetyldeoxynivalenol co-treated with deoxynivalenol co-treated with zearalenol co-treated with Zearalenone] results in decreased activity of THRB protein
CTD
PMID:27481073
NCBI chr15:10,115,954...10,465,231
Ensembl chr15:10,115,954...10,313,680
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Tnf
tumor necrosis factor
increases expression multiple interactions
ISO
3-acetyldeoxynivalenol results in increased expression of TNF mRNA 3-acetyldeoxynivalenol results in increased expression of and results in increased secretion of TNF protein; 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of and results in increased secretion of TNF protein]; 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of TNF mRNA]
CTD
PMID:24793808 PMID:35413383
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
G
Xbp1
X-box binding protein 1
increases expression multiple interactions
ISO
3-acetyldeoxynivalenol results in increased expression of XBP1 mRNA 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of XBP1 mRNA]
CTD
PMID:35413383
NCBI chr14:84,604,623...84,609,707
Ensembl chr14:84,604,107...84,609,706
G
A2m
alpha-2-macroglobulin
decreases expression
ISO
deoxynivalenol results in decreased expression of A2M protein
CTD
PMID:39638853
NCBI chr 4:156,570,163...156,619,870
Ensembl chr 4:156,569,860...156,619,868
G
Aars1
alanyl-tRNA synthetase 1
decreases expression
ISO
deoxynivalenol results in decreased expression of AARS1 protein
CTD
PMID:39638853
NCBI chr19:55,906,694...55,930,499
Ensembl chr19:55,906,702...55,930,497
G
Aass
aminoadipate-semialdehyde synthase
decreases expression
ISO
deoxynivalenol results in decreased expression of AASS protein
CTD
PMID:39638853
NCBI chr 4:52,572,146...52,628,811
Ensembl chr 4:52,572,147...52,657,600
G
Abat
4-aminobutyrate aminotransferase
decreases expression
ISO
deoxynivalenol results in decreased expression of ABAT protein
CTD
PMID:39638853
NCBI chr10:7,503,351...7,599,474
Ensembl chr10:7,492,022...7,599,474
G
Abcb1a
ATP binding cassette subfamily B member 1A
decreases response to substance multiple interactions
ISO
ABCB1 protein results in decreased susceptibility to deoxynivalenol deoxynivalenol inhibits the reaction [valspodar inhibits the reaction [ABCB1 protein results in increased export of calcein AM]]
CTD
PMID:29174985
NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135
G
Abcb6
ATP binding cassette subfamily B member 6
decreases expression
ISO
deoxynivalenol results in decreased expression of ABCB6 protein
CTD
PMID:39638853
NCBI chr 9:84,117,222...84,125,939
Ensembl chr 9:84,117,220...84,125,526
G
Abcc2
ATP binding cassette subfamily C member 2
decreases expression
ISO
deoxynivalenol results in decreased expression of ABCC2 protein
CTD
PMID:39638853
NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471
G
Abcc3
ATP binding cassette subfamily C member 3
decreases expression
ISO
deoxynivalenol results in decreased expression of ABCC3 mRNA
CTD
PMID:31863870
NCBI chr10:79,793,571...79,839,528
Ensembl chr10:79,793,583...79,839,494
G
Abcf1
ATP binding cassette subfamily F member 1
decreases phosphorylation
ISO
deoxynivalenol results in decreased phosphorylation of ABCF1 protein
CTD
PMID:23352502 PMID:23811945
NCBI chr20:2,807,315...2,820,240
Ensembl chr20:2,807,106...2,820,240
G
Abcf2
ATP binding cassette subfamily F member 2
increases expression
ISO
deoxynivalenol results in increased expression of ABCF2 protein
CTD
PMID:39638853
NCBI chr 4:11,485,865...11,500,067
Ensembl chr 4:11,487,395...11,500,053
G
Abi1
abl-interactor 1
increases phosphorylation
ISO
deoxynivalenol results in increased phosphorylation of ABI1 protein
CTD
PMID:23352502
NCBI chr17:90,006,917...90,088,002
Ensembl chr17:90,006,925...90,087,827
G
Ablim1
actin-binding LIM protein 1
increases expression
ISO
deoxynivalenol results in increased expression of ABLIM1 protein
CTD
PMID:39638853
NCBI chr 1:266,088,868...266,377,169
Ensembl chr 1:266,088,870...266,377,098
G
Abraxas2
abraxas 2, BRISC complex subunit
increases expression
ISO
deoxynivalenol results in increased expression of ABRAXAS2 mRNA
CTD
PMID:31863870
NCBI chr 1:197,077,177...197,102,753
Ensembl chr 1:197,077,158...197,102,757
G
Acaa1a
acetyl-CoA acyltransferase 1A
decreases expression
ISO
deoxynivalenol results in decreased expression of ACAA1 protein
CTD
PMID:39638853
NCBI chr 8:127,956,126...127,966,348
Ensembl chr 8:127,956,129...127,966,241
G
Acadsb
acyl-CoA dehydrogenase, short/branched chain
decreases expression
ISO
deoxynivalenol results in decreased expression of ACADSB protein
CTD
PMID:39638853
NCBI chr 1:195,619,088...195,660,564
Ensembl chr 1:195,619,038...195,660,561
G
Acan
aggrecan
decreases expression
ISO
deoxynivalenol results in decreased expression of ACAN mRNA
CTD
PMID:31863870
NCBI chr 1:142,390,951...142,453,779
Ensembl chr 1:142,390,951...142,453,779
G
Acin1
apoptotic chromatin condensation inducer 1
affects phosphorylation
ISO
deoxynivalenol affects the phosphorylation of ACIN1 protein
CTD
PMID:23811945
NCBI chr15:32,072,121...32,117,004
Ensembl chr15:32,072,123...32,117,166
G
Acly
ATP citrate lyase
decreases expression
ISO
deoxynivalenol results in decreased expression of ACLY protein
CTD
PMID:39638853
NCBI chr10:85,912,402...85,964,605
Ensembl chr10:85,912,402...85,963,631
G
Acot1
acyl-CoA thioesterase 1
decreases expression
ISO
deoxynivalenol results in decreased expression of ACOT1 protein
CTD
PMID:39638853
NCBI chr 6:109,367,274...109,375,268
Ensembl chr 6:109,367,268...109,380,749
G
Acot9
acyl-CoA thioesterase 9
increases expression
ISO
deoxynivalenol results in increased expression of ACOT9 protein
CTD
PMID:39638853
NCBI chr X:43,922,943...43,973,311
Ensembl chr X:43,914,923...43,973,205
G
Acsf2
acyl-CoA synthetase family member 2
decreases expression
ISO
deoxynivalenol results in decreased expression of ACSF2 protein
CTD
PMID:39638853
NCBI chr10:80,001,389...80,043,796
Ensembl chr10:80,001,389...80,045,050
G
Acsl4
acyl-CoA synthetase long-chain family member 4
decreases expression increases expression
ISO
deoxynivalenol results in decreased expression of ACSL4 protein deoxynivalenol results in increased expression of ACSL4 mRNA; deoxynivalenol results in increased expression of ACSL4 protein
CTD
PMID:33890134 PMID:39638853 PMID:39983889
NCBI chr X:110,739,633...110,803,416
Ensembl chr X:110,739,648...110,803,261
G
Acsl5
acyl-CoA synthetase long-chain family member 5
decreases expression
ISO
deoxynivalenol results in decreased expression of ACSL5 protein
CTD
PMID:39638853
NCBI chr 1:264,294,851...264,341,943
Ensembl chr 1:264,294,864...264,341,943
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Acss1
acyl-CoA synthetase short-chain family member 1
decreases expression
ISO
deoxynivalenol results in decreased expression of ACSS1 protein
CTD
PMID:39638853
NCBI chr 3:159,910,809...159,960,748
Ensembl chr 3:159,910,809...159,960,748
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Acss2
acyl-CoA synthetase short-chain family member 2
decreases expression
ISO
deoxynivalenol results in decreased expression of ACSS2 protein
CTD
PMID:39638853
NCBI chr 3:164,464,124...164,507,607
Ensembl chr 3:164,464,055...164,519,830
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Acta1
actin, alpha 1, skeletal muscle
affects phosphorylation
ISO
deoxynivalenol affects the phosphorylation of ACTA1 protein
CTD
PMID:23811945
NCBI chr19:68,781,168...68,784,194
Ensembl chr19:68,781,168...68,786,178
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Actbl2
actin, beta-like 2
decreases phosphorylation
ISO
deoxynivalenol results in decreased phosphorylation of ACTBL2 protein
CTD
PMID:23352502
NCBI chr 2:44,591,391...44,594,138
Ensembl chr 2:44,591,391...44,594,138
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Adam10
ADAM metallopeptidase domain 10
decreases expression
ISO
deoxynivalenol results in decreased expression of ADAM10 protein
CTD
PMID:39638853
NCBI chr 8:80,226,862...80,358,728
Ensembl chr 8:80,226,674...80,361,600
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Afg2b
AFG2 AAA ATPase homolog B
increases expression
ISO
deoxynivalenol results in increased expression of AFG2B mRNA
CTD
PMID:31863870
NCBI chr 3:130,148,061...130,162,458
Ensembl chr 3:130,148,301...130,162,112
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Afp
alpha-fetoprotein
decreases expression
ISO
deoxynivalenol results in decreased expression of AFP protein
CTD
PMID:39638853
NCBI chr14:17,857,584...17,875,645
Ensembl chr14:17,857,584...17,875,649
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Agfg1
ArfGAP with FG repeats 1
affects phosphorylation increases expression
ISO
deoxynivalenol affects the phosphorylation of AGFG1 protein deoxynivalenol results in increased expression of AGFG1 mRNA
CTD
PMID:23811945 PMID:31863870
NCBI chr 9:91,572,962...91,630,688
Ensembl chr 9:91,573,157...91,626,910
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Agrn
agrin
decreases expression
ISO
deoxynivalenol results in decreased expression of AGRN protein
CTD
PMID:39638853
NCBI chr 5:172,031,528...172,064,429
Ensembl chr 5:172,031,528...172,064,539
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Agt
angiotensinogen
decreases expression
ISO
deoxynivalenol results in decreased expression of AGT protein
CTD
PMID:39638853
NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944
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Agxt
alanine--glyoxylate aminotransferase
decreases expression
ISO
deoxynivalenol results in decreased expression of AGXT protein
CTD
PMID:39638853
NCBI chr 9:101,122,793...101,132,746
Ensembl chr 9:101,122,793...101,132,745
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Ahnak
AHNAK nucleoprotein
affects phosphorylation decreases expression
ISO
deoxynivalenol affects the phosphorylation of AHNAK protein deoxynivalenol results in decreased expression of AHNAK protein
CTD
PMID:23352502 PMID:23811945 PMID:39638853
NCBI chr 1:215,311,289...215,400,010
Ensembl chr 1:215,321,931...215,400,675
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Ahr
aryl hydrocarbon receptor
multiple interactions increases expression
ISO
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of AHR mRNA]]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of AHR protein]]; 6-formylindolo(3,2-b)carbazole promotes the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of AHR mRNA]]; 6-formylindolo(3,2-b)carbazole promotes the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of AHR protein]]; sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of AHR mRNA]; sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of AHR protein] deoxynivalenol results in increased expression of AHR mRNA; deoxynivalenol results in increased expression of AHR protein
CTD
PMID:35381244
NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901
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Ahsg
alpha-2-HS-glycoprotein
decreases expression
ISO
deoxynivalenol results in decreased expression of AHSG protein
CTD
PMID:39638853
NCBI chr11:91,625,975...91,632,583
Ensembl chr11:91,625,975...91,634,039
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Ajuba
ajuba LIM protein
decreases phosphorylation
ISO
deoxynivalenol results in decreased phosphorylation of AJUBA protein
CTD
PMID:33890134
NCBI chr15:31,989,796...32,000,042
Ensembl chr15:31,989,799...32,000,042
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Ak7
adenylate kinase 7
decreases expression
ISO
deoxynivalenol results in decreased expression of AK7 mRNA
CTD
PMID:26763390
NCBI chr 6:130,376,499...130,444,674
Ensembl chr 6:130,376,550...130,444,677
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Akap8l
A-kinase anchoring protein 8 like
increases expression
ISO
deoxynivalenol results in increased expression of AKAP8L mRNA
CTD
PMID:31863870
NCBI chr 7:11,983,215...12,012,843
Ensembl chr 7:11,982,721...12,012,811
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Akr1b7
aldo-keto reductase family 1, member B7
multiple interactions
ISO
[Selenomethionine co-treated with deoxynivalenol] results in increased expression of AKR1B7 mRNA
CTD
PMID:38040082
NCBI chr 4:64,043,901...64,083,751
Ensembl chr 4:64,020,686...64,064,909
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Akt1
AKT serine/threonine kinase 1
multiple interactions increases phosphorylation decreases phosphorylation
ISO
AKT1 protein affects the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; AKT1 protein affects the reaction [deoxynivalenol results in increased phosphorylation of CREB1 protein]; deoxynivalenol results in increased phosphorylation of and results in increased activity of AKT1 protein; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased phosphorylation of AKT1 protein]; lauric acid inhibits the reaction [deoxynivalenol results in decreased phosphorylation of AKT1 protein] [Zearalenone co-treated with deoxynivalenol] results in decreased phosphorylation of AKT1 protein
CTD
PMID:15976193 PMID:16424113 PMID:24937323 PMID:34506767 PMID:35090964 PMID:37705238 More...
NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610
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Alb
albumin
decreases expression multiple interactions increases expression
ISO
deoxynivalenol results in decreased expression of ALB protein [deoxynivalenol co-treated with Zearalenone] affects the expression of ALB mRNA; [deoxynivalenol co-treated with Zearalenone] results in decreased expression of ALB protein; [deoxynivalenol co-treated with Zearalenone] results in increased expression of ALB mRNA deoxynivalenol results in decreased expression of ALB mRNA; deoxynivalenol results in decreased expression of ALB protein deoxynivalenol results in increased expression of ALB mRNA
CTD
PMID:25445755 PMID:28865950 PMID:28935499
NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865
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Aldh1a1
aldehyde dehydrogenase 1 family, member A1
decreases expression
ISO
deoxynivalenol results in decreased expression of ALDH1A1 protein
CTD
PMID:39638853
NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:227,427,070...227,579,500
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Aldh2
aldehyde dehydrogenase 2 family member
decreases expression
ISO
deoxynivalenol results in decreased expression of ALDH2 protein
CTD
PMID:39638853
NCBI chr12:40,610,244...40,643,220
Ensembl chr12:40,610,224...40,643,219
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Aldh3b1
aldehyde dehydrogenase 3 family, member B1
decreases expression
ISO
deoxynivalenol results in decreased expression of ALDH3B1 mRNA
CTD
PMID:31863870
NCBI chr 1:210,574,545...210,605,188
Ensembl chr 1:210,573,661...210,610,538
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Aldh6a1
aldehyde dehydrogenase 6 family, member A1
decreases expression
ISO
deoxynivalenol results in decreased expression of ALDH6A1 protein
CTD
PMID:39638853
NCBI chr 6:109,809,092...109,829,725
Ensembl chr 6:109,809,122...109,829,743
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Aldh7a1
aldehyde dehydrogenase 7 family, member A1
decreases expression
ISO
deoxynivalenol results in decreased expression of ALDH7A1 protein
CTD
PMID:39638853
NCBI chr18:52,208,035...52,240,293
Ensembl chr18:52,204,161...52,240,467
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Aldoa
aldolase, fructose-bisphosphate A
decreases expression
ISO
deoxynivalenol results in decreased expression of ALDOA protein
CTD
PMID:39638853
NCBI chr 1:190,832,820...190,838,021
Ensembl chr 1:190,832,820...190,838,211
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Aldob
aldolase, fructose-bisphosphate B
increases expression multiple interactions
ISO
deoxynivalenol results in increased expression of ALDOB mRNA [deoxynivalenol co-treated with Zearalenone] affects the expression of ALDOB mRNA; [deoxynivalenol co-treated with Zearalenone] results in increased expression of ALDOB mRNA
CTD
PMID:28865950 PMID:28935499
NCBI chr 5:68,684,541...68,697,582
Ensembl chr 5:68,684,542...68,716,740
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Aldoc
aldolase, fructose-bisphosphate C
decreases expression
ISO
deoxynivalenol results in decreased expression of ALDOC protein
CTD
PMID:39638853
NCBI chr10:63,715,544...63,719,133
Ensembl chr10:63,715,489...63,719,133
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Alkbh1
alkB homolog 1, histone H2A dioxygenase
increases expression
ISO
deoxynivalenol results in increased expression of ALKBH1 mRNA
CTD
PMID:31863870
NCBI chr 6:112,799,234...112,819,708
Ensembl chr 6:112,799,234...112,819,708
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Alox12
arachidonate 12-lipoxygenase, 12S type
decreases expression
ISO
deoxynivalenol results in decreased expression of ALOX12 mRNA
CTD
PMID:39983889
NCBI chr10:55,456,923...55,469,239
Ensembl chr10:55,456,928...55,469,199
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Alpi
alkaline phosphatase, intestinal
multiple interactions
ISO
deoxynivalenol results in decreased expression of and results in decreased activity of ALPI protein
CTD
PMID:20362602
NCBI chr 9:95,221,314...95,224,780
Ensembl chr 9:95,221,314...95,224,780
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Alpk2
alpha-kinase 2
decreases expression
ISO
deoxynivalenol results in decreased expression of ALPK2 mRNA
CTD
PMID:31863870
NCBI chr18:61,045,717...61,161,703
Ensembl chr18:61,045,380...61,175,985
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Ambp
alpha-1-microglobulin/bikunin precursor
decreases expression
ISO
deoxynivalenol results in decreased expression of AMBP protein
CTD
PMID:39638853
NCBI chr 5:81,583,621...81,593,938
Ensembl chr 5:81,583,622...81,593,850
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Amigo2
adhesion molecule with Ig like domain 2
decreases expression
ISO
deoxynivalenol results in decreased expression of AMIGO2 mRNA
CTD
PMID:31863870
NCBI chr 7:130,270,639...130,273,735
Ensembl chr 7:130,270,554...130,282,218
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Angptl7
angiopoietin like 7
decreases expression
ISO
deoxynivalenol results in decreased expression of ANGPTL7 mRNA
CTD
PMID:31863870
NCBI chr 5:164,215,223...164,220,408
Ensembl chr 5:164,215,223...164,220,584
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Ankrd13c
ankyrin repeat domain 13C
increases expression
ISO
deoxynivalenol results in increased expression of ANKRD13C mRNA
CTD
PMID:31863870
NCBI chr 2:249,679,752...249,729,272
Ensembl chr 2:249,681,872...249,729,272
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Ankrd37
ankyrin repeat domain 37
decreases expression
ISO
deoxynivalenol results in decreased expression of ANKRD37 mRNA
CTD
PMID:31863870
NCBI chr16:53,001,487...53,004,545
Ensembl chr16:52,994,740...53,004,545
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Anln
anillin, actin binding protein
increases expression
ISO
deoxynivalenol results in increased expression of ANLN mRNA
CTD
PMID:31863870
NCBI chr 8:29,134,222...29,197,513
Ensembl chr 8:29,134,222...29,197,513
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Anpep
alanyl aminopeptidase, membrane
decreases expression
ISO
deoxynivalenol results in decreased expression of ANPEP mRNA; deoxynivalenol results in decreased expression of ANPEP protein
CTD
PMID:31863870 PMID:39638853
NCBI chr 1:143,176,645...143,219,447
Ensembl chr 1:143,176,645...143,195,101
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Anxa6
annexin A6
decreases expression
ISO
deoxynivalenol results in decreased expression of ANXA6 protein
CTD
PMID:39638853
NCBI chr10:39,602,106...39,657,183
Ensembl chr10:39,602,106...39,657,359
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Aoc1
amine oxidase, copper containing 1
increases activity multiple interactions
ISO
deoxynivalenol results in increased activity of AOC1 protein Curcumin inhibits the reaction [deoxynivalenol results in increased activity of AOC1 protein]
CTD
PMID:35817260
NCBI chr 4:79,143,126...79,162,705
Ensembl chr 4:79,143,126...79,162,704
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Aplp2
amyloid beta precursor like protein 2
decreases expression
ISO
deoxynivalenol results in decreased expression of APLP2 protein
CTD
PMID:39638853
NCBI chr 8:37,857,407...37,920,487
Ensembl chr 8:37,857,407...37,920,031
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Apoa1
apolipoprotein A1
decreases expression
ISO
deoxynivalenol results in decreased expression of APOA1 protein
CTD
PMID:39638853
NCBI chr 8:55,423,945...55,425,729
Ensembl chr 8:55,423,825...55,425,729
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Apob
apolipoprotein B
decreases expression
ISO
deoxynivalenol results in decreased expression of APOB protein
CTD
PMID:39638853
NCBI chr 6:36,563,704...36,603,300
Ensembl chr 6:36,563,704...36,611,814
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Apoc3
apolipoprotein C3
decreases expression
ISO
deoxynivalenol results in decreased expression of APOC3 protein
CTD
PMID:39638853
NCBI chr 8:55,428,172...55,430,352
Ensembl chr 8:55,428,024...55,458,679
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Apoe
apolipoprotein E
decreases expression
ISO
deoxynivalenol results in decreased expression of APOE protein
CTD
PMID:39638853
NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:88,481,385...88,485,855
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Apoh
apolipoprotein H
decreases expression
ISO
deoxynivalenol results in decreased expression of APOH protein
CTD
PMID:39638853
NCBI chr10:93,841,992...93,855,897
Ensembl chr10:93,841,966...93,857,127
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Ar
androgen receptor
decreases activity multiple interactions
ISO
deoxynivalenol results in decreased activity of AR protein [15-acetyldeoxynivalenol co-treated with 3-acetyldeoxynivalenol co-treated with deoxynivalenol co-treated with zearalenol co-treated with Zearalenone] results in decreased activity of AR protein; [15-acetyldeoxynivalenol co-treated with 3-acetyldeoxynivalenol co-treated with deoxynivalenol] results in decreased activity of AR protein
CTD
PMID:27481073
NCBI chr X:67,135,317...67,304,476
Ensembl chr X:67,135,317...67,304,467
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Arglu1
arginine and glutamate rich 1
decreases phosphorylation
ISO
deoxynivalenol results in decreased phosphorylation of ARGLU1 protein
CTD
PMID:23811945
NCBI chr16:87,455,097...87,479,148
Ensembl chr16:87,455,113...87,479,148
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Arhgap45
Rho GTPase activating protein 45
affects phosphorylation
ISO
deoxynivalenol affects the phosphorylation of ARHGAP45 protein
CTD
PMID:23811945
NCBI chr 7:10,325,515...10,340,955
Ensembl chr 7:10,325,539...10,341,890
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Ark2n
arkadia (RNF111) N-terminal like PKA signaling regulator 2N
increases expression
ISO
deoxynivalenol results in increased expression of ARK2N mRNA
CTD
PMID:31863870
NCBI chr18:73,431,104...73,520,759
Ensembl chr18:73,431,104...73,518,144
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Armc10
armadillo repeat containing 10
affects phosphorylation increases phosphorylation
ISO
deoxynivalenol affects the phosphorylation of ARMC10 protein deoxynivalenol results in increased phosphorylation of ARMC10 protein
CTD
PMID:23352502 PMID:23811945
NCBI chr 4:14,291,211...14,306,799
Ensembl chr 4:14,291,211...14,306,817
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Ascc3
activating signal cointegrator 1 complex subunit 3
increases expression
ISO
deoxynivalenol results in increased expression of ASCC3 mRNA
CTD
PMID:31863870
NCBI chr20:55,089,430...55,372,374
Ensembl chr20:55,255,503...55,372,374
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Ascl2
achaete-scute family bHLH transcription factor 2
increases expression
ISO
deoxynivalenol results in increased expression of ASCL2 mRNA
CTD
PMID:19438726
NCBI chr 1:207,578,447...207,665,126
Ensembl chr 1:207,578,449...207,580,856
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Ascl4
achaete-scute family bHLH transcription factor 4
increases expression
ISO
deoxynivalenol results in increased expression of ASCL4 mRNA
CTD
PMID:37419272
NCBI chr 7:19,828,710...19,830,952
Ensembl chr 7:19,828,710...19,830,952
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Asgr1
asialoglycoprotein receptor 1
decreases expression
ISO
deoxynivalenol results in decreased expression of ASGR1 protein
CTD
PMID:39638853
NCBI chr10:55,274,299...55,278,323
Ensembl chr10:55,274,706...55,278,322
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Asgr2
asialoglycoprotein receptor 2
decreases expression
ISO
deoxynivalenol results in decreased expression of ASGR2 protein
CTD
PMID:39638853
NCBI chr10:55,320,082...55,333,294
Ensembl chr10:55,320,091...55,333,263
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Asns
asparagine synthetase (glutamine-hydrolyzing)
decreases expression
ISO
deoxynivalenol results in decreased expression of ASNS mRNA; deoxynivalenol results in decreased expression of ASNS protein
CTD
PMID:31863870 PMID:39638853
NCBI chr 4:36,752,061...36,769,970
Ensembl chr 4:36,751,802...36,776,050
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Atad2
ATPase family, AAA domain containing 2
increases expression
ISO
deoxynivalenol results in increased expression of ATAD2 protein
CTD
PMID:39638853
NCBI chr 7:91,523,626...91,566,238
Ensembl chr 7:91,523,626...91,566,238
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Atf1
activating transcription factor 1
multiple interactions increases phosphorylation increases expression
ISO
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in increased phosphorylation of ATF1 protein]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased phosphorylation of ATF1 protein]; SB 203580 inhibits the reaction [deoxynivalenol results in increased phosphorylation of ATF1 protein] deoxynivalenol results in increased expression of ATF1 mRNA
CTD
PMID:16424113 PMID:22846391
NCBI chr 7:133,240,774...133,283,488
Ensembl chr 7:133,241,197...133,283,485
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Atf2
activating transcription factor 2
increases expression multiple interactions increases phosphorylation affects localization
ISO
deoxynivalenol results in increased expression of ATF2 mRNA 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased phosphorylation of ATF2 protein] deoxynivalenol affects the localization of ATF2 protein
CTD
PMID:12604842 PMID:15772366 PMID:22846391
NCBI chr 3:79,125,814...79,202,896
Ensembl chr 3:79,126,705...79,202,745
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Atf3
activating transcription factor 3
multiple interactions decreases expression increases expression increases response to substance decreases degradation
ISO
[[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which affects the localization of ELAVL1 protein] which co-treated with deoxynivalenol] promotes the reaction [[ELAVL1 protein binds to ATF3 3' UTR] which results in increased stability of ATF3 mRNA]; [[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of ATF3 mRNA; [Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] promotes the reaction [deoxynivalenol results in increased expression of ATF3 mRNA]; ATF3 protein affects the reaction [[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] affects the phosphorylation of RELA protein]; ATF3 protein affects the reaction [deoxynivalenol results in increased expression of EGR1 protein]; EP300 protein affects the reaction [deoxynivalenol results in increased expression of ATF3 protein alternative form]; KAT2A protein affects the reaction [deoxynivalenol results in increased expression of ATF3 protein alternative form]; KAT2B protein affects the reaction [deoxynivalenol results in increased expression of ATF3 protein alternative form]; N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea inhibits the reaction [deoxynivalenol results in decreased degradation of ATF3 protein]; SB 203580 inhibits the reaction [deoxynivalenol results in decreased degradation of ATF3 mRNA]; SB 203580 inhibits the reaction [deoxynivalenol results in decreased degradation of ATF3 protein] deoxynivalenol results in decreased expression of ATF3 mRNA deoxynivalenol results in increased expression of ATF3 mRNA; deoxynivalenol results in increased expression of ATF3 protein; deoxynivalenol results in increased expression of ATF3 protein alternative form ATF3 protein results in increased susceptibility to deoxynivalenol deoxynivalenol results in decreased degradation of ATF3 mRNA; deoxynivalenol results in decreased degradation of ATF3 protein
CTD
PMID:19101521 PMID:19360757 PMID:21074547 PMID:22003189 PMID:22846391 PMID:23253260 PMID:30286430 PMID:35314294 More...
NCBI chr13:105,274,103...105,331,653
Ensembl chr13:105,282,440...105,295,750
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Atf6
activating transcription factor 6
multiple interactions increases expression
ISO
ATF6 protein affects the reaction [deoxynivalenol results in increased expression of IL6 mRNA] deoxynivalenol results in increased expression of ATF6 protein deoxynivalenol results in increased expression of ATF6 mRNA
CTD
PMID:19336499 PMID:20682335 PMID:22846391
NCBI chr13:85,460,312...85,639,959
Ensembl chr13:85,462,840...85,640,033
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Atg14
autophagy related 14
increases expression
ISO
deoxynivalenol results in increased expression of ATG14 mRNA
CTD
PMID:31863870
NCBI chr15:23,275,457...23,306,817
Ensembl chr15:23,275,457...23,306,815
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Atg4b
autophagy related 4B, cysteine peptidase
increases expression
ISO
deoxynivalenol results in increased expression of ATG4B mRNA
CTD
PMID:31863870
NCBI chr 9:101,729,772...101,761,456
Ensembl chr 9:101,726,782...101,761,622
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Atg5
autophagy related 5
increases expression multiple interactions
ISO
deoxynivalenol results in increased expression of ATG5 mRNA; deoxynivalenol results in increased expression of ATG5 protein 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of ATG5 mRNA]]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of ATG5 protein]]; 6-formylindolo(3,2-b)carbazole promotes the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of ATG5 mRNA]]; 6-formylindolo(3,2-b)carbazole promotes the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of ATG5 protein]]; sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of ATG5 mRNA]; sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of ATG5 protein]
CTD
PMID:35381244
NCBI chr20:49,380,835...49,471,826
Ensembl chr20:49,380,813...49,471,821
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Atl2
atlastin GTPase 2
increases expression
ISO
deoxynivalenol results in increased expression of ATL2 protein
CTD
PMID:39638853
NCBI chr 6:20,891,220...20,932,644
Ensembl chr 6:20,891,227...20,933,320
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Atp10a
ATPase phospholipid transporting 10A (putative)
decreases expression
ISO
deoxynivalenol results in decreased expression of ATP10A mRNA
CTD
PMID:31863870
NCBI chr 1:118,692,456...118,866,117
Ensembl chr 1:118,692,478...118,866,114
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Atp1a1
ATPase Na+/K+ transporting subunit alpha 1
decreases expression
ISO
deoxynivalenol results in decreased expression of ATP1A1 protein
CTD
PMID:39638853
NCBI chr 2:191,709,311...191,737,414
Ensembl chr 2:191,709,311...191,737,425
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Atp5f1c
ATP synthase F1 subunit gamma
decreases expression
ISO
deoxynivalenol results in decreased expression of ATP5F1C protein
CTD
PMID:33890134
NCBI chr17:73,333,584...73,355,872
Ensembl chr17:73,333,588...73,383,073
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Atp5pd
ATP synthase peripheral stalk subunit d
decreases expression
ISO
deoxynivalenol results in decreased expression of ATP5PD protein
CTD
PMID:33890134
NCBI chr10:101,156,673...101,161,926
Ensembl chr10:101,156,673...101,162,954
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Atp6ap2
ATPase H+ transporting accessory protein 2
decreases expression
ISO
deoxynivalenol results in decreased expression of ATP6AP2 protein
CTD
PMID:39638853
NCBI chr X:12,856,708...12,883,670
Ensembl chr X:12,855,859...12,905,875
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Atp6v1a
ATPase H+ transporting V1 subunit A
decreases expression
ISO
deoxynivalenol results in decreased expression of ATP6V1A protein
CTD
PMID:33890134
NCBI chr11:70,066,800...70,120,603
Ensembl chr11:70,035,134...70,120,603
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Atp6v1b2
ATPase H+ transporting V1 subunit B2
decreases expression
ISO
deoxynivalenol results in decreased expression of ATP6V1B2 protein
CTD
PMID:33890134
NCBI chr16:25,384,254...25,408,388
Ensembl chr16:25,384,257...25,408,839
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Atp6v1d
ATPase H+ transporting V1 subunit D
decreases expression
ISO
deoxynivalenol results in decreased expression of ATP6V1D protein
CTD
PMID:33890134
NCBI chr 6:103,389,778...103,405,346
Ensembl chr 6:103,389,783...103,405,346
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Atp6v1g1
ATPase H+ transporting V1 subunit G1
decreases expression
ISO
deoxynivalenol results in decreased expression of ATP6V1G1 protein
CTD
PMID:33890134
NCBI chr 5:81,976,959...81,983,139
Ensembl chr 5:81,977,015...81,985,930
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Atp6v1h
ATPase H+ transporting V1 subunit H
decreases expression
ISO
deoxynivalenol results in decreased expression of ATP6V1H protein
CTD
PMID:33890134
NCBI chr 5:19,176,849...19,282,516
Ensembl chr 5:19,176,849...19,282,516
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Atp8b2
ATPase phospholipid transporting 8B2
decreases expression
ISO
deoxynivalenol results in decreased expression of ATP8B2 mRNA
CTD
PMID:31863870
NCBI chr 2:177,676,205...177,699,575
Ensembl chr 2:177,676,208...177,699,575
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Atrn
attractin
decreases expression
ISO
deoxynivalenol results in decreased expression of ATRN protein
CTD
PMID:39638853
NCBI chr 3:138,563,271...138,697,360
Ensembl chr 3:138,563,312...138,697,360
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Atrx
ATRX, chromatin remodeler
affects phosphorylation
ISO
deoxynivalenol affects the phosphorylation of ATRX protein
CTD
PMID:23811945
NCBI chr X:74,916,548...75,062,880
Ensembl chr X:74,916,548...75,062,880
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Atxn10
ataxin 10
decreases expression
ISO
deoxynivalenol results in decreased expression of ATXN10 protein
CTD
PMID:39638853
NCBI chr 7:118,321,516...118,444,967
Ensembl chr 7:118,319,490...118,445,636
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Atxn2l
ataxin 2-like
increases expression
ISO
deoxynivalenol results in increased expression of ATXN2L protein
CTD
PMID:39638853
NCBI chr 1:190,508,878...190,526,263
Ensembl chr 1:190,508,878...190,520,579
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Aurka
aurora kinase A
increases expression
ISO
deoxynivalenol results in increased expression of AURKA protein
CTD
PMID:39638853
NCBI chr 3:181,546,742...181,562,890
Ensembl chr 3:181,546,742...181,562,771
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B2m
beta-2 microglobulin
decreases expression
ISO
deoxynivalenol results in decreased expression of B2M protein
CTD
PMID:39638853
NCBI chr 3:129,549,236...129,555,354
Ensembl chr 3:129,549,318...129,555,356
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B3galt4
Beta-1,3-galactosyltransferase 4
decreases expression
ISO
deoxynivalenol results in decreased expression of B3GALT4 mRNA
CTD
PMID:26763390
NCBI chr20:4,937,974...4,939,549
Ensembl chr20:4,937,674...4,939,885
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B4gat1
beta-1,4-glucuronyltransferase 1
decreases expression
ISO
deoxynivalenol results in decreased expression of B4GAT1 protein
CTD
PMID:39638853
NCBI chr 1:211,772,644...211,774,866
Ensembl chr 1:211,772,606...211,775,442
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Bach2
BTB domain and CNC homolog 2
increases expression
ISO
deoxynivalenol results in increased expression of BACH2 mRNA
CTD
PMID:24247028
NCBI chr 5:51,428,802...51,779,030
Ensembl chr 5:51,434,870...51,774,234
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Bad
BCL2-associated agonist of cell death
increases phosphorylation
ISO
deoxynivalenol results in increased phosphorylation of BAD protein
CTD
PMID:15976193
NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:213,562,187...213,572,034
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Bag3
BAG cochaperone 3
increases expression
ISO
deoxynivalenol results in increased expression of BAG3 mRNA
CTD
PMID:22846391
NCBI chr 1:192,533,460...192,557,281
Ensembl chr 1:192,475,828...192,557,280
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Bak1
BCL2-antagonist/killer 1
increases expression
ISO
deoxynivalenol results in increased expression of BAK1 mRNA
CTD
PMID:20702593
NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,102,335...5,110,974
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Bax
BCL2 associated X, apoptosis regulator
multiple interactions increases expression affects localization decreases expression
ISO
[Zearalenone co-treated with deoxynivalenol] results in increased expression of BAX mRNA; [Zearalenone co-treated with deoxynivalenol] results in increased expression of BAX protein; Ascorbic Acid inhibits the reaction [deoxynivalenol results in increased expression of BAX protein] [deoxynivalenol co-treated with Aflatoxin B1] results in increased expression of BAX protein; Curcumin inhibits the reaction [deoxynivalenol results in increased expression of BAX mRNA]; Curcumin inhibits the reaction [deoxynivalenol results in increased expression of BAX protein]; deoxynivalenol promotes the reaction [Zearalenone results in increased expression of BAX mRNA] deoxynivalenol results in increased expression of BAX mRNA; deoxynivalenol results in increased expression of BAX protein deoxynivalenol affects the localization of BAX protein deoxynivalenol results in decreased expression of BAX mRNA
CTD
PMID:15976193 PMID:17166419 PMID:19410639 PMID:22269384 PMID:25445755 PMID:35090964 PMID:35817260 PMID:37705238 PMID:38763499 More...
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
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Baz1b
bromodomain adjacent to zinc finger domain, 1B
increases expression
ISO
deoxynivalenol results in increased expression of BAZ1B protein
CTD
PMID:39638853
NCBI chr12:27,068,541...27,126,511
Ensembl chr12:27,068,541...27,126,511
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Bbc3
Bcl-2 binding component 3
increases expression
ISO
deoxynivalenol results in increased expression of BBC3 mRNA
CTD
PMID:22846391
NCBI chr 1:86,141,450...86,150,666
Ensembl chr 1:86,141,603...86,150,666
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Bcam
basal cell adhesion molecule (Lutheran blood group)
decreases expression
ISO
deoxynivalenol results in decreased expression of BCAM protein
CTD
PMID:39638853
NCBI chr 1:88,542,971...88,557,358
Ensembl chr 1:88,542,972...88,557,888
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Bcas2
BCAS2, pre-mRNA processing factor
increases expression
ISO
deoxynivalenol results in increased expression of BCAS2 protein
CTD
PMID:39638853
NCBI chr 2:193,381,000...193,388,881
Ensembl chr 2:193,380,982...193,388,878
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Bcl10
BCL10, immune signaling adaptor
increases expression
ISO
deoxynivalenol results in increased expression of BCL10 mRNA
CTD
PMID:22846391
NCBI chr 2:237,501,181...237,510,821
Ensembl chr 2:237,501,134...237,511,829
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Bcl2
BCL2, apoptosis regulator
multiple interactions decreases expression increases expression
ISO
Ascorbic Acid inhibits the reaction [deoxynivalenol results in decreased expression of BCL2 protein] deoxynivalenol results in decreased expression of BCL2 mRNA; deoxynivalenol results in decreased expression of BCL2 protein [deoxynivalenol co-treated with Aflatoxin B1] results in decreased expression of BCL2 protein; Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of BCL2 mRNA]; Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of BCL2 protein]; deoxynivalenol promotes the reaction [Aflatoxin B1 results in decreased expression of BCL2 mRNA]; Selenomethionine inhibits the reaction [deoxynivalenol results in decreased expression of BCL2 protein] deoxynivalenol results in increased expression of BCL2 mRNA
CTD
PMID:17166419 PMID:22269384 PMID:25445755 PMID:35817260 PMID:37705238 PMID:38040082 PMID:38763499 More...
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
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Bcl2l1
Bcl2-like 1
decreases expression
ISO
deoxynivalenol results in decreased expression of BCL2L1 mRNA
CTD
PMID:22846391
NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907 Ensembl chr 1:161,745,540...161,764,907
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Bcl2l13
Bcl2-like 13
increases expression
ISO
deoxynivalenol results in increased expression of BCL2L13 mRNA
CTD
PMID:22846391
NCBI chr 4:155,728,284...155,785,058
Ensembl chr 4:155,728,284...155,781,158
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Bcl6
BCL6, transcription repressor
increases expression
ISO
deoxynivalenol results in increased expression of BCL6 mRNA
CTD
PMID:22968694 PMID:31863870
NCBI chr11:90,358,753...90,382,049
Ensembl chr11:90,358,753...90,382,047
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Bclaf1
BCL2-associated transcription factor 1
increases expression affects phosphorylation
ISO
deoxynivalenol results in increased expression of BCLAF1 mRNA deoxynivalenol affects the phosphorylation of BCLAF1 protein
CTD
PMID:22846391 PMID:23352502 PMID:23811945
NCBI chr 1:16,904,572...16,937,106
Ensembl chr 1:16,914,118...16,936,801
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Becn1
beclin 1
increases expression decreases expression multiple interactions
ISO
deoxynivalenol results in increased expression of BECN1 mRNA deoxynivalenol results in decreased expression of BECN1 protein 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of BECN1 mRNA]]; 6-formylindolo(3,2-b)carbazole promotes the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of BECN1 mRNA]]; Selenomethionine inhibits the reaction [deoxynivalenol results in decreased expression of BECN1 protein]; sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of BECN1 mRNA]
CTD
PMID:34677630 PMID:35381244 PMID:38040082
NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,731,650...86,747,002
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Bend7
BEN domain containing 7
increases expression
ISO
deoxynivalenol results in increased expression of BEND7 mRNA
CTD
PMID:31863870
NCBI chr17:78,392,489...78,475,459
Ensembl chr17:78,393,601...78,475,223
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Bid
BH3 interacting domain death agonist
decreases expression
ISO
deoxynivalenol results in decreased expression of BID mRNA
CTD
PMID:22269384
NCBI chr 4:155,785,366...155,808,775
Ensembl chr 4:155,785,377...155,808,275
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Bin1
bridging integrator 1
decreases phosphorylation
ISO
deoxynivalenol results in decreased phosphorylation of BIN1 protein
CTD
PMID:23352502
NCBI chr18:24,282,840...24,341,461
Ensembl chr18:24,283,801...24,341,458
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Bmal1
basic helix-loop-helix ARNT like 1
multiple interactions
ISO
BMAL1 protein inhibits the reaction [deoxynivalenol results in increased activity of GOT1 protein]; BMAL1 protein inhibits the reaction [deoxynivalenol results in increased activity of GPT protein]; BMAL1 protein inhibits the reaction [deoxynivalenol results in increased expression of IL1B protein]; BMAL1 protein inhibits the reaction [deoxynivalenol results in increased expression of IL6 protein]; BMAL1 protein inhibits the reaction [deoxynivalenol results in increased expression of TNF protein]; BMAL1 protein promotes the reaction [deoxynivalenol results in decreased expression of CLOCK protein]; BMAL1 protein promotes the reaction [deoxynivalenol results in decreased expression of NR1D1 protein]; BMAL1 protein promotes the reaction [deoxynivalenol results in decreased expression of PER2 protein]; BMAL1 protein promotes the reaction [deoxynivalenol results in decreased expression of PER3 protein]; deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of CLOCK mRNA]; deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of CRY1 mRNA]; deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of CRY1 protein]; deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of CRY2 mRNA]; deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of CRY2 protein]; deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of NR1D1 mRNA]; deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of NR1D2 mRNA]; deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of PER1 mRNA]; deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of PER1 protein]; deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of PER3 mRNA]
CTD
PMID:36602574
NCBI chr 1:176,766,222...176,864,741
Ensembl chr 1:176,829,305...176,864,739
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Bmp2
bone morphogenetic protein 2
increases expression
ISO
deoxynivalenol results in increased expression of BMP2 mRNA
CTD
PMID:31863870
NCBI chr 3:141,264,648...141,275,416
Ensembl chr 3:141,264,646...141,274,760
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Bms1
BMS1 ribosome biogenesis factor
increases expression
ISO
deoxynivalenol results in increased expression of BMS1 protein
CTD
PMID:39638853
NCBI chr 4:153,230,471...153,267,437
Ensembl chr 4:153,230,471...153,267,429
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Bnip1
BCL2 interacting protein 1
increases expression
ISO
deoxynivalenol results in increased expression of BNIP1 mRNA
CTD
PMID:22846391
NCBI chr10:16,891,317...16,903,561
Ensembl chr10:16,891,317...16,903,561
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Bnip2
BCL2 interacting protein 2
increases phosphorylation
ISO
deoxynivalenol results in increased phosphorylation of BNIP2 protein
CTD
PMID:23352502
NCBI chr 8:79,521,375...79,539,148
Ensembl chr 8:79,521,363...79,547,368
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Bop1
BOP1 ribosomal biogenesis factor
increases expression
ISO
deoxynivalenol results in increased expression of BOP1 protein
CTD
PMID:39638853
NCBI chr 7:110,052,716...110,076,529
Ensembl chr 7:110,052,720...110,076,529
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Bptf
bromodomain PHD finger transcription factor
increases phosphorylation
ISO
deoxynivalenol results in increased phosphorylation of BPTF protein
CTD
PMID:23352502
NCBI chr10:92,480,007...92,582,485
Ensembl chr10:92,480,007...92,582,413
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Brd3
bromodomain containing 3
increases phosphorylation
ISO
deoxynivalenol results in increased phosphorylation of BRD3 protein
CTD
PMID:23811945
NCBI chr 3:31,173,332...31,227,749
Ensembl chr 3:31,173,332...31,227,629
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Bst1
bone marrow stromal cell antigen 1
decreases expression
ISO
deoxynivalenol results in decreased expression of BST1 mRNA
CTD
PMID:31863870
NCBI chr14:71,466,179...71,482,671
Ensembl chr14:71,466,180...71,482,647
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Bub1b
BUB1 mitotic checkpoint serine/threonine kinase B
increases expression
ISO
deoxynivalenol results in increased expression of BUB1B mRNA
CTD
PMID:31863870
NCBI chr 3:126,017,019...126,069,470
Ensembl chr 3:126,017,045...126,069,796
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Bub3
BUB3 mitotic checkpoint protein
increases expression
ISO
deoxynivalenol results in increased expression of BUB3 mRNA; deoxynivalenol results in increased expression of BUB3 protein
CTD
PMID:31863870 PMID:39638853
NCBI chr 1:195,760,532...195,771,140
Ensembl chr 1:195,758,105...195,791,028
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Bysl
bystin-like
increases expression
ISO
deoxynivalenol results in increased expression of BYSL protein
CTD
PMID:39638853
NCBI chr 9:20,880,341...20,890,092
Ensembl chr 9:20,880,026...20,890,900
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C3
complement C3
increases expression decreases expression
ISO
deoxynivalenol results in increased expression of C3 mRNA deoxynivalenol results in decreased expression of C3 protein
CTD
PMID:22968694 PMID:39638853
NCBI chr 9:2,174,412...2,201,339
Ensembl chr 9:2,174,412...2,201,339
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C3ar1
complement C3a receptor 1
increases expression
ISO
deoxynivalenol results in increased expression of C3AR1 mRNA
CTD
PMID:12604170 PMID:22968694
NCBI chr 4:157,747,419...157,756,609
Ensembl chr 4:157,746,089...157,776,323
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C4a
complement C4A
decreases expression
ISO
deoxynivalenol results in decreased expression of C4A protein
CTD
PMID:39638853
NCBI chr20:4,010,306...4,024,707
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C4b
complement C4B
increases expression
ISO
deoxynivalenol results in increased expression of C4B mRNA
CTD
PMID:22968694
NCBI chr20:4,201,979...4,216,292
Ensembl chr20:4,201,961...4,216,289
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Cacna1d
calcium voltage-gated channel subunit alpha1 D
increases expression
ISO
deoxynivalenol results in increased expression of CACNA1D mRNA
CTD
PMID:23792671
NCBI chr16:5,233,682...5,527,549
Ensembl chr16:5,233,690...5,674,692
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Cacng6
calcium voltage-gated channel auxiliary subunit gamma 6
decreases expression
ISO
deoxynivalenol results in decreased expression of CACNG6 mRNA
CTD
PMID:26763390
NCBI chr 1:74,648,342...74,663,351
Ensembl chr 1:74,648,063...74,662,753
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Cadm1
cell adhesion molecule 1
decreases expression
ISO
deoxynivalenol results in decreased expression of CADM1 protein
CTD
PMID:39638853
NCBI chr 8:56,744,374...57,075,264
Ensembl chr 8:56,744,372...57,080,192
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Canx
calnexin
decreases phosphorylation
ISO
deoxynivalenol results in decreased phosphorylation of CANX protein
CTD
PMID:23811945
NCBI chr10:35,124,941...35,157,954
Ensembl chr10:35,124,941...35,157,857
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Card11
caspase recruitment domain family, member 11
affects phosphorylation
ISO
deoxynivalenol affects the phosphorylation of CARD11 protein
CTD
PMID:23811945
NCBI chr12:18,735,088...18,872,045
Ensembl chr12:18,735,088...18,872,045
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Casc3
CASC3 exon junction complex subunit
increases phosphorylation
ISO
deoxynivalenol results in increased phosphorylation of CASC3 protein
CTD
PMID:23811945
NCBI chr10:84,264,157...84,286,639
Ensembl chr10:84,265,033...84,286,637
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Cask
calcium/calmodulin dependent serine protein kinase
increases expression
ISO
deoxynivalenol results in increased expression of CASK protein
CTD
PMID:39638853
NCBI chr X:11,572,328...11,915,831
Ensembl chr X:11,572,636...11,911,948
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Casp1
caspase 1
increases expression increases cleavage multiple interactions
ISO
deoxynivalenol results in increased expression of CASP1 mRNA deoxynivalenol results in increased cleavage of CASP1 protein deoxynivalenol promotes the reaction [fumonisin B1 results in increased cleavage of CASP1 protein]; fumonisin B1 promotes the reaction [deoxynivalenol results in increased cleavage of CASP1 protein]
CTD
PMID:36309173
NCBI chr 8:10,746,338...10,882,295
Ensembl chr 8:10,746,333...10,882,275
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Casp3
caspase 3
increases activity increases cleavage increases expression multiple interactions decreases expression
ISO EXP
deoxynivalenol results in increased activity of CASP3 protein deoxynivalenol results in increased cleavage of CASP3 protein deoxynivalenol results in increased expression of CASP3 mRNA; deoxynivalenol results in increased expression of CASP3 protein benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased expression of CASP3 mRNA]; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased expression of CASP3 protein] 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [deoxynivalenol results in increased activity of CASP3 protein]; 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased activity of CASP3 protein]; [deoxynivalenol co-treated with Aflatoxin B1] results in increased expression of CASP3 protein; acetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [deoxynivalenol results in increased expression of and results in increased cleavage of CASP3 protein]; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased expression of and results in increased cleavage of CASP3 protein]; Curcumin inhibits the reaction [deoxynivalenol results in increased activity of CASP3 protein]; deoxynivalenol promotes the reaction [Aflatoxin B1 results in increased expression of CASP3 mRNA]; deoxynivalenol results in increased activity of and results in increased cleavage of CASP3 protein; deoxynivalenol results in increased expression of and results in increased cleavage of CASP3 protein; HCK protein affects the reaction [deoxynivalenol results in increased activity of CASP3 protein]; lauric acid inhibits the reaction [deoxynivalenol results in increased cleavage of CASP3 protein]; pifithrin inhibits the reaction [deoxynivalenol results in increased activity of CASP3 protein]; SB 203580 inhibits the reaction [deoxynivalenol results in increased activity of CASP3 protein]; Zearalenone promotes the reaction [deoxynivalenol results in increased expression of CASP3 mRNA] deoxynivalenol results in decreased expression of CASP3 protein [Zearalenone co-treated with Aflatoxin B1] promotes the reaction [deoxynivalenol results in increased expression of CASP3 mRNA]; [Zearalenone co-treated with deoxynivalenol] results in increased expression of CASP3 protein; Aflatoxin B1 promotes the reaction [deoxynivalenol results in increased expression of CASP3 mRNA]; Ascorbic Acid inhibits the reaction [deoxynivalenol results in increased expression of CASP3 protein]; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [deoxynivalenol results in decreased expression of and results in increased cleavage of CASP3 protein]; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [deoxynivalenol results in decreased expression of and results in increased cleavage of CASP3 protein]; deoxynivalenol results in decreased expression of and results in increased cleavage of CASP3 protein
CTD
PMID:15772366 PMID:15976193 PMID:17166419 PMID:19410639 PMID:19664677 PMID:22269384 PMID:22491426 PMID:25445755 PMID:27757495 PMID:30668976 PMID:34506767 PMID:34673182 PMID:34677630 PMID:35090964 PMID:35314294 PMID:35817260 PMID:35925383 PMID:37705238 PMID:38763499 More...
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
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Casp7
caspase 7
increases activity
ISO
deoxynivalenol results in increased activity of CASP7 protein
CTD
PMID:27757495
NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:265,442,676...265,482,512
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Casp8
caspase 8
increases expression multiple interactions
ISO EXP
deoxynivalenol results in increased expression of CASP8 mRNA benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased expression of CASP8 mRNA] [Aflatoxin B1 co-treated with deoxynivalenol] promotes the reaction [Zearalenone results in increased expression of CASP8 mRNA]; [Aflatoxin B1 co-treated with deoxynivalenol] results in increased expression of CASP8 mRNA; [Zearalenone co-treated with Aflatoxin B1] promotes the reaction [deoxynivalenol results in increased expression of CASP8 mRNA]; [Zearalenone co-treated with deoxynivalenol] promotes the reaction [Aflatoxin B1 results in increased expression of CASP8 mRNA]; Zearalenone promotes the reaction [[Aflatoxin B1 co-treated with deoxynivalenol] results in increased expression of CASP8 mRNA] deoxynivalenol results in increased activity of and results in increased cleavage of CASP8 protein
CTD
PMID:22491426 PMID:22846391 PMID:30668976 PMID:34673182
NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699
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Casp9
caspase 9
decreases expression multiple interactions increases expression increases activity
ISO EXP
deoxynivalenol results in decreased expression of CASP9 protein benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased expression of CASP9 mRNA] Zearalenone promotes the reaction [[Aflatoxin B1 co-treated with deoxynivalenol] results in increased expression of CASP9 mRNA] [deoxynivalenol co-treated with Aflatoxin B1] results in increased expression of CASP9 protein; deoxynivalenol results in increased activity of and results in increased cleavage of CASP9 protein deoxynivalenol results in increased expression of CASP9 mRNA; deoxynivalenol results in increased expression of CASP9 protein deoxynivalenol results in increased activity of CASP9 protein
CTD
PMID:22269384 PMID:22491426 PMID:30668976 PMID:34673182 PMID:35314294 PMID:38763499 More...
Ensembl chr 5:159,391,188...159,409,648
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Casr
calcium-sensing receptor
multiple interactions
ISO
CASR affects the reaction [deoxynivalenol results in increased secretion of CCK protein]
CTD
PMID:25787141
NCBI chr11:77,738,398...77,813,639
Ensembl chr11:77,740,614...77,810,167
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Cat
catalase
increases expression decreases activity multiple interactions decreases expression increases activity
ISO EXP
deoxynivalenol results in increased expression of CAT mRNA; deoxynivalenol results in increased expression of CAT protein deoxynivalenol results in decreased activity of CAT protein Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of CAT mRNA] deoxynivalenol results in increased activity of CAT protein Lutein inhibits the reaction [deoxynivalenol results in increased expression of CAT protein]
CTD
PMID:20347963 PMID:34400200 PMID:34673182 PMID:35314294 PMID:35817260 PMID:37705238 More...
NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
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Cbll1
Cbl proto-oncogene like 1
increases expression
ISO
deoxynivalenol results in increased expression of CBLL1 mRNA
CTD
PMID:31863870
NCBI chr 6:53,798,712...53,812,890
Ensembl chr 6:53,798,712...53,813,880
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Cbs
cystathionine beta synthase
decreases expression
ISO
deoxynivalenol results in decreased expression of CBS mRNA
CTD
PMID:31863870
NCBI chr20:9,709,394...9,733,925
Ensembl chr20:9,709,395...9,734,066
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Cbx5
chromobox 5
increases phosphorylation
ISO
deoxynivalenol results in increased phosphorylation of CBX5 protein
CTD
PMID:23811945
NCBI chr 7:136,203,827...136,254,575
Ensembl chr 7:136,211,649...136,229,118
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Ccdc112
coiled-coil domain containing 112
increases expression
ISO
deoxynivalenol results in increased expression of CCDC112 mRNA
CTD
PMID:31863870
NCBI chr18:41,184,769...41,218,958
Ensembl chr18:41,184,769...41,218,958
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Ccdc137
coiled-coil domain containing 137
increases expression
ISO
deoxynivalenol results in increased expression of CCDC137 protein
CTD
PMID:39638853
NCBI chr10:106,229,099...106,235,502
Ensembl chr10:106,229,099...106,235,502
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Ccdc86
coiled-coil domain containing 86
increases expression
ISO
deoxynivalenol results in increased expression of CCDC86 protein
CTD
PMID:39638853
NCBI chr 1:217,015,059...217,021,439
Ensembl chr 1:217,014,848...217,021,468
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Cck
cholecystokinin
increases secretion multiple interactions increases expression
ISO
deoxynivalenol results in increased secretion of CCK protein 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [deoxynivalenol results in increased secretion of CCK protein]; 2-aminoethyl diphenylborinate inhibits the reaction [deoxynivalenol results in increased secretion of CCK protein]; [N-(2-hydroxy-3-(2-cyano-3-chlorophenoxy)propyl)-1,1-dimethyl-2-(2-nephthyl)ethylamine co-treated with Ruthenium Red] inhibits the reaction [deoxynivalenol results in increased expression of CCK protein]; CASR affects the reaction [deoxynivalenol results in increased secretion of CCK protein]; Egtazic Acid inhibits the reaction [deoxynivalenol results in increased secretion of CCK protein]; N-(2-hydroxy-3-(2-cyano-3-chlorophenoxy)propyl)-1,1-dimethyl-2-(2-nephthyl)ethylamine inhibits the reaction [deoxynivalenol results in increased expression of CCK protein]; Nitrendipine inhibits the reaction [deoxynivalenol results in increased secretion of CCK protein]; Ruthenium Red inhibits the reaction [deoxynivalenol results in increased expression of CCK protein]; triphenylphosphine oxide inhibits the reaction [deoxynivalenol results in increased secretion of CCK protein]; TRPA1 affects the reaction [deoxynivalenol results in increased secretion of CCK protein]
CTD
PMID:22903826 PMID:24385417 PMID:25787141 PMID:26979077
NCBI chr 8:130,031,012...130,037,702
Ensembl chr 8:130,031,013...130,037,686
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Ccl1
C-C motif chemokine ligand 1
increases expression
ISO
deoxynivalenol results in increased expression of CCL1 mRNA
CTD
PMID:22968694
NCBI chr10:67,625,962...67,628,740
Ensembl chr10:67,625,962...67,628,790
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Ccl11
C-C motif chemokine ligand 11
increases expression
ISO
deoxynivalenol results in increased expression of CCL11 mRNA
CTD
PMID:22968694
NCBI chr10:67,525,975...67,530,576
Ensembl chr10:67,525,862...67,530,575
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Ccl12
C-C motif chemokine ligand 12
increases expression
ISO
deoxynivalenol results in increased expression of CCL12 mRNA
CTD
PMID:22968694
NCBI chr10:67,567,876...67,569,426
Ensembl chr10:67,567,876...67,569,426
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Ccl17
C-C motif chemokine ligand 17
increases expression
ISO
deoxynivalenol results in increased expression of CCL17 mRNA
CTD
PMID:22968694
NCBI chr19:10,208,120...10,218,340
Ensembl chr19:10,208,120...10,209,895
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Ccl2
C-C motif chemokine ligand 2
increases expression multiple interactions
ISO
deoxynivalenol results in increased expression of CCL2 mRNA; deoxynivalenol results in increased expression of CCL2 protein Fatty Acids, Omega-3 inhibits the reaction [deoxynivalenol results in increased expression of CCL2 mRNA]
CTD
PMID:15371230 PMID:15681167 PMID:17090620 PMID:22846391 PMID:22968694 PMID:24793808 More...
NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875
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Ccl20
C-C motif chemokine ligand 20
increases expression
ISO
deoxynivalenol results in increased expression of CCL20 mRNA
CTD
PMID:27757495 PMID:35314294
NCBI chr 9:91,837,139...91,839,736
Ensembl chr 9:91,836,946...91,839,736
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Ccl22
C-C motif chemokine ligand 22
increases expression
ISO
deoxynivalenol results in increased expression of CCL22 mRNA
CTD
PMID:22968694
NCBI chr19:10,263,589...10,270,359
Ensembl chr19:10,263,589...10,270,359
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Ccl24
C-C motif chemokine ligand 24
increases expression
ISO
deoxynivalenol results in increased expression of CCL24 mRNA
CTD
PMID:22968694
NCBI chr12:26,737,423...26,741,420
Ensembl chr12:26,737,439...26,750,924
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Ccl25
C-C motif chemokine ligand 25
decreases expression
ISO
deoxynivalenol results in decreased expression of CCL25 mRNA
CTD
PMID:22968694
NCBI chr12:7,505,231...7,514,402
Ensembl chr12:7,505,235...7,514,385
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Ccl3
C-C motif chemokine ligand 3
increases expression
ISO
deoxynivalenol results in increased expression of CCL3 mRNA
CTD
PMID:22846391 PMID:22968694
NCBI chr10:68,948,889...68,950,439
Ensembl chr10:68,948,889...68,950,439
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Ccl4
C-C motif chemokine ligand 4
increases expression
ISO
deoxynivalenol results in increased expression of CCL4 mRNA
CTD
PMID:21074547 PMID:22846391 PMID:22968694 PMID:27757495
NCBI chr10:68,963,893...68,965,728
Ensembl chr10:68,950,289...68,965,722
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Ccl5
C-C motif chemokine ligand 5
increases expression multiple interactions
ISO
deoxynivalenol results in increased expression of CCL5 mRNA benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased expression of CCL5 mRNA]
CTD
PMID:22968694 PMID:27757495 PMID:35925383
NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,738,651...68,824,884
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Ccl7
C-C motif chemokine ligand 7
multiple interactions increases expression
ISO
Fatty Acids, Omega-3 inhibits the reaction [deoxynivalenol results in increased expression of CCL7 mRNA]
CTD
PMID:15371230 PMID:15681167 PMID:22968694 PMID:24793808
NCBI chr10:67,514,095...67,515,945
Ensembl chr10:67,514,091...67,515,947
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Ccn1
cellular communication network factor 1
increases expression
ISO
deoxynivalenol results in increased expression of CCN1 mRNA
CTD
PMID:15371230
NCBI chr 2:237,222,730...237,225,689
Ensembl chr 2:237,222,432...237,225,883
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Ccn2
cellular communication network factor 2
increases expression
ISO
deoxynivalenol results in increased expression of CCN2 mRNA
CTD
PMID:35588983
NCBI chr 1:22,621,498...22,624,614
Ensembl chr 1:22,621,501...22,624,976
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Ccnb1
cyclin B1
increases expression multiple interactions
ISO
deoxynivalenol results in increased expression of CCNB1 mRNA 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in increased expression of CCNB1 mRNA]
CTD
PMID:34677630
NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:33,646,252...33,655,225
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Ccnd1
cyclin D1
increases expression multiple interactions
ISO
deoxynivalenol results in increased expression of CCND1 mRNA; deoxynivalenol results in increased expression of CCND1 protein Celecoxib inhibits the reaction [deoxynivalenol results in increased expression of CCND1 protein]
CTD
PMID:22454431 PMID:24937323 PMID:32416088
NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810
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Ccne1
cyclin E1
decreases expression
ISO
deoxynivalenol results in decreased expression of CCNE1 mRNA
CTD
PMID:27456127
NCBI chr 1:99,918,672...99,927,986
Ensembl chr 1:99,918,674...99,927,822
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Ccng2
cyclin G2
increases expression
ISO
deoxynivalenol results in increased expression of CCNG2 mRNA
CTD
PMID:30169763
NCBI chr14:15,088,694...15,097,190
Ensembl chr14:15,088,695...15,096,206
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Ccny
cyclin Y
affects phosphorylation
ISO
deoxynivalenol affects the phosphorylation of CCNY protein
CTD
PMID:23811945
NCBI chr17:62,079,925...62,207,780
Ensembl chr17:62,079,925...62,207,979
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Ccr1
C-C motif chemokine receptor 1
increases expression
ISO
deoxynivalenol results in increased expression of CCR1 mRNA
CTD
PMID:22968694
NCBI chr 8:132,433,711...132,439,266
Ensembl chr 8:132,431,592...132,439,374
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Ccr2
C-C motif chemokine receptor 2
increases expression
ISO
deoxynivalenol results in increased expression of CCR2 mRNA
CTD
PMID:22968694
NCBI chr 8:132,611,883...132,619,106
Ensembl chr 8:132,611,410...132,620,059
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Ccr3
C-C motif chemokine receptor 3
increases expression
ISO
deoxynivalenol results in increased expression of CCR3 mRNA
CTD
PMID:22968694
NCBI chr 8:132,463,533...132,511,601
Ensembl chr 8:132,463,788...132,511,593
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Ccr4
C-C motif chemokine receptor 4
increases expression
ISO
deoxynivalenol results in increased expression of CCR4 mRNA
CTD
PMID:27757495
NCBI chr 8:123,054,505...123,060,244
Ensembl chr 8:123,054,324...123,077,642
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Ccr7
C-C motif chemokine receptor 7
increases expression
ISO
deoxynivalenol results in increased expression of CCR7 mRNA
CTD
PMID:22968694
NCBI chr10:84,594,399...84,604,514
Ensembl chr10:84,593,594...84,604,501
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Cd14
CD14 molecule
multiple interactions
ISO
deoxynivalenol inhibits the reaction [IFNG protein results in increased expression of CD14 protein]
CTD
PMID:19549553
NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,608,883...28,611,292
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Cd248
CD248 molecule
decreases expression
ISO
deoxynivalenol results in decreased expression of CD248 mRNA
CTD
PMID:31863870
NCBI chr 1:211,803,052...211,805,616
Ensembl chr 1:211,801,934...211,805,776
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Cd276
Cd276 molecule
decreases expression
ISO
deoxynivalenol results in decreased expression of CD276 protein
CTD
PMID:39638853
NCBI chr 8:67,833,587...67,863,918
Ensembl chr 8:67,829,048...67,864,505
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Cd40
CD40 molecule
decreases expression
ISO
deoxynivalenol results in decreased expression of CD40 mRNA
CTD
PMID:22968694
NCBI chr 3:174,209,113...174,224,592
Ensembl chr 3:174,209,719...174,224,847
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Cd46
CD46 molecule
decreases expression
ISO
deoxynivalenol results in decreased expression of CD46 protein
CTD
PMID:39638853
NCBI chr13:109,104,122...109,134,903
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Cd55
CD55 molecule (Cromer blood group)
increases expression
ISO
deoxynivalenol results in increased expression of CD55 mRNA
CTD
PMID:22846391 PMID:24247028
NCBI chr13:44,409,574...44,438,913
Ensembl chr13:44,409,587...44,438,107
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Cd68
Cd68 molecule
increases expression
ISO
deoxynivalenol results in increased expression of CD68 mRNA
CTD
PMID:25549547
NCBI chr10:54,880,562...54,882,441
Ensembl chr10:54,880,563...54,882,540
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Cd69
Cd69 molecule
increases expression
ISO
deoxynivalenol results in increased expression of CD69 mRNA
CTD
PMID:22846391 PMID:24247028
NCBI chr 4:164,411,485...164,419,403
Ensembl chr 4:164,411,485...164,419,509
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Cd74
CD74 molecule
decreases expression
ISO
deoxynivalenol results in decreased expression of CD74 protein
CTD
PMID:39638853
NCBI chr18:56,527,071...56,536,406
Ensembl chr18:56,527,132...56,536,410
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Cd80
Cd80 molecule
increases expression
ISO
deoxynivalenol results in increased expression of CD80 mRNA
CTD
PMID:21074547
NCBI chr11:75,760,073...75,798,978
Ensembl chr11:75,760,147...75,797,540
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Cd86
CD86 molecule
increases expression
ISO
deoxynivalenol results in increased expression of CD86 mRNA
CTD
PMID:21074547
NCBI chr11:77,647,565...77,706,178
Ensembl chr11:77,647,600...77,725,361
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Cdan1
codanin 1
increases expression
ISO
deoxynivalenol results in increased expression of CDAN1 mRNA
CTD
PMID:31863870
NCBI chr 3:128,129,664...128,143,520
Ensembl chr 3:128,129,301...128,143,549
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Cdc5l
cell division cycle 5-like
increases expression
ISO
deoxynivalenol results in increased expression of CDC5L protein
CTD
PMID:39638853
NCBI chr 9:23,062,397...23,100,901
Ensembl chr 9:23,062,205...23,100,899
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Cdh13
cadherin 13
decreases expression
ISO
deoxynivalenol results in decreased expression of CDH13 mRNA
CTD
PMID:31863870
NCBI chr19:63,258,251...64,296,122
Ensembl chr19:63,258,122...64,296,119
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Cdh2
cadherin 2
decreases expression
ISO
deoxynivalenol results in decreased expression of CDH2 protein
CTD
PMID:39638853
NCBI chr18:8,051,097...8,265,288
Ensembl chr18:8,051,097...8,265,288
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Cdk1
cyclin-dependent kinase 1
increases expression multiple interactions
ISO
deoxynivalenol results in increased expression of CDK1 mRNA 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in increased expression of CDK1 mRNA]
CTD
PMID:31863870 PMID:34677630
NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,265,289...19,280,455
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Cdkn1a
cyclin-dependent kinase inhibitor 1A
increases expression multiple interactions decreases degradation
ISO
deoxynivalenol results in increased expression of CDKN1A mRNA; deoxynivalenol results in increased expression of CDKN1A protein 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in increased expression of CDKN1A mRNA]; EGR1 protein affects the reaction [deoxynivalenol results in increased expression of CDKN1A protein]; U 0126 inhibits the reaction [deoxynivalenol results in decreased degradation of CDKN1A mRNA]
CTD
PMID:18006205 PMID:22454431 PMID:30169763 PMID:30286430 PMID:31863870 PMID:34677630 More...
NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
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Cdkn3
cyclin-dependent kinase inhibitor 3
increases expression
ISO
deoxynivalenol results in increased expression of CDKN3 mRNA
CTD
PMID:31863870
NCBI chr15:22,502,299...22,513,725
Ensembl chr15:22,502,382...22,513,722
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Cdv3
carnitine deficiency-associated gene expressed in ventricle 3
increases expression
ISO
deoxynivalenol results in increased expression of CDV3 protein
CTD
PMID:39638853
NCBI chr 8:112,812,898...112,826,073
Ensembl chr 8:112,813,952...112,826,056
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Cebpa
CCAAT/enhancer binding protein alpha
multiple interactions decreases expression
ISO
[deoxynivalenol co-treated with Zearalenone] results in decreased expression of CEBPA mRNA deoxynivalenol results in decreased expression of CEBPA mRNA
CTD
PMID:28865950 PMID:28935499
NCBI chr 1:96,896,584...96,899,256
Ensembl chr 1:96,896,171...96,899,309
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Cebpb
CCAAT/enhancer binding protein beta
multiple interactions increases activity affects localization
ISO
4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased activity of CEBPB protein] deoxynivalenol affects the localization of CEBPB protein
CTD
PMID:12604842 PMID:15772366
NCBI chr 3:176,817,005...176,818,436
Ensembl chr 3:176,816,859...176,838,072
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Cemip2
cell migration inducing hyaluronidase 2
increases expression
ISO
deoxynivalenol results in increased expression of CEMIP2 protein
CTD
PMID:39638853
NCBI chr 1:228,756,826...228,834,313
Ensembl chr 1:228,757,466...228,832,906
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Cenpw
centromere protein W
increases expression
ISO
deoxynivalenol results in increased expression of CENPW mRNA
CTD
PMID:31863870
NCBI chr 1:29,353,939...29,359,109
Ensembl chr 1:29,353,970...29,359,109
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Cercam
cerebral endothelial cell adhesion molecule
decreases expression
ISO
deoxynivalenol results in decreased expression of CERCAM mRNA
CTD
PMID:31863870
NCBI chr 3:33,515,513...33,553,817
Ensembl chr 3:33,486,664...33,553,813
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Cers2
ceramide synthase 2
increases expression
ISO
deoxynivalenol results in increased expression of CERS2 protein
CTD
PMID:39638853
NCBI chr 2:185,579,511...185,587,789
Ensembl chr 2:185,579,119...185,588,839
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Ces2h
carboxylesterase 2H
decreases expression
ISO
deoxynivalenol results in decreased expression of CES2 protein
CTD
PMID:39638853
NCBI chr19:49,884,164...49,898,764
Ensembl chr19:49,884,164...49,898,752
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Cgref1
cell growth regulator with EF hand domain 1
decreases expression
ISO
deoxynivalenol results in decreased expression of CGREF1 mRNA
CTD
PMID:31863870
NCBI chr 6:31,151,795...31,163,801
Ensembl chr 6:31,151,795...31,163,800
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Chac1
ChaC glutathione-specific gamma-glutamylcyclotransferase 1
decreases expression
ISO
deoxynivalenol results in decreased expression of CHAC1 mRNA
CTD
PMID:23253260
NCBI chr 3:126,796,131...126,799,352
Ensembl chr 3:126,796,024...126,799,361
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Champ1
chromosome alignment maintaining phosphoprotein 1
affects phosphorylation
ISO
deoxynivalenol affects the phosphorylation of CHAMP1 protein
CTD
PMID:23352502
NCBI chr16:82,436,172...82,447,144
Ensembl chr16:82,434,823...82,458,984
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Cherp
calcium homeostasis endoplasmic reticulum protein
increases expression
ISO
deoxynivalenol results in increased expression of CHERP protein
CTD
PMID:39638853
NCBI chr16:17,401,497...17,414,549
Ensembl chr16:17,401,497...17,414,549
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Chka
choline kinase alpha
increases expression
ISO
deoxynivalenol results in increased expression of CHKA mRNA
CTD
PMID:31863870
NCBI chr 1:210,506,069...210,554,753
Ensembl chr 1:210,506,056...210,554,752
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Chlsn
cholesin
increases expression
ISO
deoxynivalenol results in increased expression of C7ORF50 protein
CTD
PMID:39638853
NCBI chr12:20,298,968...20,402,890
Ensembl chr12:20,388,520...20,402,922
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Chn1
chimerin 1
decreases expression
ISO
deoxynivalenol results in decreased expression of CHN1 mRNA
CTD
PMID:31863870
NCBI chr 3:78,917,329...79,084,040
Ensembl chr 3:78,917,329...79,084,197
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Chordc1
cysteine and histidine rich domain containing 1
increases expression
ISO
deoxynivalenol results in increased expression of CHORDC1 mRNA; deoxynivalenol results in increased expression of CHORDC1 protein
CTD
PMID:31863870 PMID:39638853
NCBI chr 8:23,650,721...23,674,786
Ensembl chr 8:23,650,865...23,677,696
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Chtop
chromatin target of PRMT1
increases expression
ISO
deoxynivalenol results in increased expression of CHTOP protein
CTD
PMID:39638853
NCBI chr 2:178,278,848...178,291,142
Ensembl chr 2:178,278,848...178,290,348
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Chuk
component of inhibitor of nuclear factor kappa B kinase complex
increases phosphorylation increases expression
ISO
deoxynivalenol results in increased phosphorylation of CHUK protein deoxynivalenol results in increased expression of CHUK mRNA
CTD
PMID:20633634 PMID:34400200
NCBI chr 1:252,908,748...252,944,273
Ensembl chr 1:252,908,749...252,944,273
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Cish
cytokine inducible SH2-containing protein
increases expression
ISO
deoxynivalenol results in increased expression of CISH mRNA
CTD
PMID:19625342
NCBI chr 8:116,850,969...116,855,917
Ensembl chr 8:116,850,773...116,855,986
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Ckap2
cytoskeleton associated protein 2
increases expression
ISO
deoxynivalenol results in increased expression of CKAP2 mRNA
CTD
PMID:31863870
NCBI chr16:76,542,114...76,567,297
Ensembl chr16:76,542,104...76,567,352
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Ckap5
cytoskeleton associated protein 5
increases expression
ISO
deoxynivalenol results in increased expression of CKAP5 mRNA
CTD
PMID:31863870
NCBI chr 3:97,946,966...98,049,050
Ensembl chr 3:97,947,031...98,049,049
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Cks1b
CDC28 protein kinase regulatory subunit 1B
increases expression
ISO
deoxynivalenol results in increased expression of CKS1B mRNA
CTD
PMID:31863870
NCBI chr 2:177,130,751...177,135,333
Ensembl chr 2:177,130,777...177,135,365
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Cldn1
claudin 1
increases expression decreases expression multiple interactions affects expression
ISO
deoxynivalenol results in increased expression of CLDN1 mRNA deoxynivalenol results in decreased expression of CLDN1 mRNA; deoxynivalenol results in decreased expression of CLDN1 protein 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of CLDN1 mRNA]]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide promotes the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of CLDN1 protein]]; 6-formylindolo(3,2-b)carbazole inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of CLDN1 mRNA]]; 6-formylindolo(3,2-b)carbazole inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of CLDN1 protein]]; Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of CLDN1 mRNA]; Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of CLDN1 protein]; lauric acid inhibits the reaction [deoxynivalenol results in decreased expression of CLDN1 protein]; sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of CLDN1 mRNA]; sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of CLDN1 protein] [deoxynivalenol co-treated with Zearalenone] results in decreased expression of CLDN1 mRNA; [deoxynivalenol co-treated with Zearalenone] results in decreased expression of CLDN1 protein; deoxynivalenol results in decreased expression of and affects the localization of CLDN1 protein deoxynivalenol affects the expression of CLDN1 protein
CTD
PMID:24568843 PMID:28865950 PMID:28935499 PMID:34506767 PMID:35381244 PMID:35817260 More...
NCBI chr11:87,926,376...87,941,533
Ensembl chr11:87,926,337...87,941,529
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Cldn2
claudin 2
affects expression increases expression
ISO
deoxynivalenol affects the expression of CLDN2 protein deoxynivalenol results in increased expression of CLDN2 mRNA
CTD
PMID:24568843
NCBI chr X:108,248,383...108,258,847
Ensembl chr X:108,237,676...108,262,377
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Cldn3
claudin 3
multiple interactions increases expression affects expression
ISO
deoxynivalenol results in decreased expression of and affects the localization of CLDN3 protein [deoxynivalenol results in increased susceptibility to Antigens] which results in decreased expression of CLDN3 mRNA deoxynivalenol results in increased expression of CLDN3 mRNA deoxynivalenol affects the expression of CLDN3 protein
CTD
PMID:24568843 PMID:28935500
NCBI chr12:27,345,075...27,346,547
Ensembl chr12:27,345,076...27,348,841
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Cldn4
claudin 4
decreases expression increases expression multiple interactions
ISO
deoxynivalenol results in decreased expression of CLDN4 protein deoxynivalenol results in increased expression of CLDN4 mRNA deoxynivalenol results in decreased expression of and affects the localization of CLDN4 protein
CTD
PMID:19289138 PMID:20362602 PMID:24568843
NCBI chr12:27,388,160...27,389,958
Ensembl chr12:27,387,981...27,389,958
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Clic3
chloride intracellular channel 3
decreases expression
ISO
deoxynivalenol results in decreased expression of CLIC3 mRNA
CTD
PMID:31863870
NCBI chr 3:28,670,176...28,672,166
Ensembl chr 3:28,670,229...28,675,723
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Clock
clock circadian regulator
multiple interactions decreases expression
ISO
BMAL1 protein promotes the reaction [deoxynivalenol results in decreased expression of CLOCK protein]; deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of CLOCK mRNA]
CTD
PMID:36602574
NCBI chr14:32,262,747...32,346,872
Ensembl chr14:32,262,750...32,346,872
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Clptm1
CLPTM1 regulator of GABA type A receptor forward trafficking
decreases expression
ISO
deoxynivalenol results in decreased expression of CLPTM1 protein
CTD
PMID:39638853
NCBI chr 1:88,417,447...88,449,047
Ensembl chr 1:88,417,447...88,449,446
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Clu
clusterin
decreases expression
ISO
deoxynivalenol results in decreased expression of CLU protein
CTD
PMID:39638853
NCBI chr15:44,336,619...44,375,861
Ensembl chr15:44,359,914...44,375,860
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Cnih1
cornichon family member 1
decreases expression
ISO
deoxynivalenol results in decreased expression of CNIH1 protein
CTD
PMID:39638853
NCBI chr15:22,517,755...22,529,651
Ensembl chr15:22,497,340...22,529,578
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Cnpy2
canopy FGF signaling regulator 2
decreases expression
ISO
deoxynivalenol results in decreased expression of CNPY2 mRNA
CTD
PMID:31863870
NCBI chr 7:1,332,293...1,338,081
Ensembl chr 7:1,334,335...1,340,333
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Col15a1
collagen type XV alpha 1 chain
decreases expression
ISO
deoxynivalenol results in decreased expression of COL15A1 mRNA
CTD
PMID:31863870
NCBI chr 5:66,297,546...66,403,172
Ensembl chr 5:66,297,461...66,403,170
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Col18a1
collagen type XVIII alpha 1 chain
decreases expression
ISO
deoxynivalenol results in decreased expression of COL18A1 protein
CTD
PMID:39638853
NCBI chr20:11,473,645...11,582,111
Ensembl chr20:11,473,645...11,582,112
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Col4a1
collagen type IV alpha 1 chain
decreases expression
ISO
deoxynivalenol results in decreased expression of COL4A1 mRNA
CTD
PMID:31863870
NCBI chr16:84,885,597...84,996,482
Ensembl chr16:84,885,597...84,996,482
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Col5a1
collagen type V alpha 1 chain
decreases expression
ISO
deoxynivalenol results in decreased expression of COL5A1 mRNA
CTD
PMID:31863870
NCBI chr 3:31,606,475...31,755,097
Ensembl chr 3:31,606,486...31,753,020
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Col6a2
collagen type VI alpha 2 chain
decreases expression
ISO
deoxynivalenol results in decreased expression of COL6A2 mRNA
CTD
PMID:31863870
NCBI chr20:12,021,182...12,048,932
Ensembl chr20:12,021,265...12,057,042
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Comt
catechol-O-methyltransferase
decreases phosphorylation
ISO
deoxynivalenol results in decreased phosphorylation of COMT protein
CTD
PMID:23811945
NCBI chr11:96,072,371...96,091,956
Ensembl chr11:96,072,489...96,092,533
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Copb2
COPI coat complex subunit beta 2
decreases expression
ISO
deoxynivalenol results in decreased expression of COPB2 protein
CTD
PMID:39638853
NCBI chr 8:108,040,687...108,062,810
Ensembl chr 8:108,040,693...108,064,550
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Coq8a
coenzyme Q8A
decreases expression
ISO
deoxynivalenol results in decreased expression of COQ8A protein
CTD
PMID:39638853
NCBI chr13:94,436,680...94,465,535
Ensembl chr13:94,436,546...94,463,378
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Coro1a
coronin 1A
affects phosphorylation
ISO
deoxynivalenol affects the phosphorylation of CORO1A protein
CTD
PMID:23811945
NCBI chr 1:190,726,129...190,731,133
Ensembl chr 1:190,726,130...190,731,102
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Coro2a
coronin 2A
decreases expression
ISO
deoxynivalenol results in decreased expression of CORO2A protein
CTD
PMID:39638853
NCBI chr 5:65,623,820...65,677,483
Ensembl chr 5:65,623,823...65,654,602
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Coro2b
coronin 2B
decreases expression
ISO
deoxynivalenol results in decreased expression of CORO2B mRNA
CTD
PMID:31863870
NCBI chr 8:71,802,329...71,912,739
Ensembl chr 8:71,802,329...71,912,739
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Cox5b
cytochrome c oxidase subunit 5B
decreases expression
ISO
deoxynivalenol results in decreased expression of COX5B protein
CTD
PMID:33890134
NCBI chr 9:46,417,735...46,419,664
Ensembl chr 9:46,417,838...46,420,403
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Cpd
carboxypeptidase D
decreases expression
ISO
deoxynivalenol results in decreased expression of CPD protein
CTD
PMID:39638853
NCBI chr10:62,121,681...62,185,638
Ensembl chr10:62,121,679...62,185,638
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Cpsf2
cleavage and polyadenylation specific factor 2
increases expression
ISO
deoxynivalenol results in increased expression of CPSF2 mRNA
CTD
PMID:31863870
NCBI chr 6:126,885,417...126,917,634
Ensembl chr 6:126,885,476...126,917,632
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Creb1
cAMP responsive element binding protein 1
multiple interactions increases phosphorylation increases activity affects localization
ISO
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in increased phosphorylation of CREB1 protein]; AKT1 protein affects the reaction [deoxynivalenol results in increased phosphorylation of CREB1 protein]; Celecoxib inhibits the reaction [deoxynivalenol results in increased phosphorylation of CREB1 protein]; deoxynivalenol promotes the reaction [CREB1 protein modified form binds to IL6 promoter]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol promotes the reaction [CREB1 protein modified form binds to IL6 promoter]]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased activity of CREB1 protein]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased phosphorylation of CREB1 protein]; SB 203580 inhibits the reaction [deoxynivalenol results in increased phosphorylation of CREB1 protein] deoxynivalenol affects the localization of CREB1 protein
CTD
PMID:12604842 PMID:16424113 PMID:32416088
NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:73,397,306...73,466,339
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Creb5
cAMP responsive element binding protein 5
increases expression
ISO
deoxynivalenol results in increased expression of CREB5 mRNA
CTD
PMID:31863870
NCBI chr 4:83,723,587...84,124,786
Ensembl chr 4:83,723,194...84,120,793
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Crebbp
CREB binding protein
increases expression
ISO
deoxynivalenol results in increased expression of CREBBP mRNA
CTD
PMID:24247028
NCBI chr10:11,842,307...11,968,266
Ensembl chr10:11,822,620...11,968,266
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Creld1
cysteine-rich with EGF-like domains 1
decreases expression
ISO
deoxynivalenol results in decreased expression of CRELD1 mRNA
CTD
PMID:31863870
NCBI chr 4:148,187,510...148,197,120
Ensembl chr 4:148,187,265...148,197,116
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Crp
C-reactive protein
increases expression
ISO
deoxynivalenol results in increased expression of CRP mRNA
CTD
PMID:22968694
NCBI chr13:87,694,062...87,695,978
Ensembl chr13:87,657,317...87,707,514
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Cry1
cryptochrome circadian regulator 1
multiple interactions
ISO
deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of CRY1 mRNA]; deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of CRY1 protein]
CTD
PMID:36602574
NCBI chr 7:20,417,526...20,481,791
Ensembl chr 7:20,417,107...20,481,822
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Cry2
cryptochrome circadian regulator 2
multiple interactions
ISO
deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of CRY2 mRNA]; deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of CRY2 protein]
CTD
PMID:36602574
NCBI chr 3:98,830,479...98,860,437
Ensembl chr 3:98,830,483...98,860,447
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Cryl1
crystallin, lambda 1
decreases expression
ISO
deoxynivalenol results in decreased expression of CRYL1 protein
CTD
PMID:39638853
NCBI chr15:35,542,628...35,661,563
Ensembl chr15:35,542,628...35,661,563
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Csde1
cold shock domain containing E1
increases expression
ISO
deoxynivalenol results in increased expression of CSDE1 protein
CTD
PMID:39638853
NCBI chr 2:193,234,546...193,271,301
Ensembl chr 2:193,243,526...193,271,301
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Csf3
colony stimulating factor 3
increases expression
ISO
deoxynivalenol results in increased expression of CSF3 mRNA
CTD
PMID:27757495
NCBI chr10:84,157,485...84,159,860
Ensembl chr10:84,157,211...84,159,860
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Cthrc1
collagen triple helix repeat containing 1
decreases expression
ISO
deoxynivalenol results in decreased expression of CTHRC1 mRNA
CTD
PMID:31863870
NCBI chr 7:72,007,372...72,017,654
Ensembl chr 7:72,007,372...72,017,654
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Ctnna1
catenin alpha 1
decreases expression
ISO
deoxynivalenol results in decreased expression of CTNNA1 protein
CTD
PMID:33890134
NCBI chr18:27,002,330...27,135,009
Ensembl chr18:26,999,820...27,135,007
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Ctnnb1
catenin beta 1
affects phosphorylation
ISO
deoxynivalenol affects the phosphorylation of CTNNB1 protein
CTD
PMID:23811945
NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662
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Ctsd
cathepsin D
decreases expression
ISO
deoxynivalenol results in decreased expression of CTSD protein
CTD
PMID:39638853
NCBI chr 1:206,956,945...206,968,821
Ensembl chr 1:206,956,944...206,968,821
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Ctso
cathepsin O
decreases expression
ISO
deoxynivalenol results in decreased expression of CTSO mRNA
CTD
PMID:31863870
NCBI chr 2:169,528,468...169,551,975
Ensembl chr 2:169,528,511...169,554,995
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Cwf19l2
CWF19 like cell cycle control factor 2
increases expression
ISO
deoxynivalenol results in increased expression of CWF19L2 mRNA
CTD
PMID:31863870
NCBI chr 6:6,036,158...6,102,686
Ensembl chr 6:6,026,861...6,102,635
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Cx3cl1
C-X3-C motif chemokine ligand 1
increases expression
ISO
deoxynivalenol results in increased expression of CX3CL1 mRNA
CTD
PMID:22846391
NCBI chr19:10,233,326...10,244,856
Ensembl chr19:10,233,329...10,242,999
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Cxcl1
C-X-C motif chemokine ligand 1
multiple interactions increases expression
ISO
[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of CXCL1 mRNA; [Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] promotes the reaction [deoxynivalenol results in increased expression of CXCL1 mRNA]; ELAVL1 protein affects the reaction [[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of CXCL1 mRNA]
CTD
PMID:22003189 PMID:27757495
NCBI chr14:17,477,542...17,479,321
Ensembl chr14:17,477,549...17,479,811
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Cxcl10
C-X-C motif chemokine ligand 10
decreases expression increases expression
ISO
deoxynivalenol results in decreased expression of CXCL10 mRNA deoxynivalenol results in increased expression of CXCL10 mRNA; deoxynivalenol results in increased expression of CXCL10 protein
CTD
PMID:15371230 PMID:22968694 PMID:34400200
NCBI chr14:15,989,066...15,991,263
Ensembl chr14:15,989,018...15,991,261
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Cxcl11
C-X-C motif chemokine ligand 11
decreases expression increases expression
ISO
deoxynivalenol results in decreased expression of CXCL11 mRNA deoxynivalenol results in increased expression of CXCL11 mRNA
CTD
PMID:22968694 PMID:27757495
NCBI chr14:15,973,728...15,976,503
Ensembl chr14:15,973,720...15,976,567
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Cxcl2
C-X-C motif chemokine ligand 2
increases expression multiple interactions
ISO
deoxynivalenol results in increased expression of CXCL2 mRNA; deoxynivalenol results in increased expression of CXCL2 protein deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of CXCL2 mRNA]; Fatty Acids, Omega-3 inhibits the reaction [deoxynivalenol results in increased expression of CXCL2 mRNA]
CTD
PMID:12604170 PMID:15371230 PMID:15681167 PMID:22968694 PMID:24793808 PMID:27757495 More...
NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,465,242...17,467,255
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Cxcl3
C-X-C motif chemokine ligand 3
multiple interactions increases expression
ISO
[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of CXCL1 mRNA; [Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] promotes the reaction [deoxynivalenol results in increased expression of CXCL1 mRNA]; ELAVL1 protein affects the reaction [[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of CXCL1 mRNA] deoxynivalenol results in increased expression of CXCL1 mRNA; deoxynivalenol results in increased expression of CXCL3 mRNA
CTD
PMID:15371230 PMID:15681167 PMID:22003189 PMID:22968694 PMID:27757495
NCBI chr14:17,571,900...17,573,624
Ensembl chr14:17,571,900...17,573,624
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Cxcl9
C-X-C motif chemokine ligand 9
increases expression
ISO
deoxynivalenol results in increased expression of CXCL9 mRNA
CTD
PMID:22968694
NCBI chr14:16,007,166...16,012,077
Ensembl chr14:16,007,204...16,014,299
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Cxcr1
C-X-C motif chemokine receptor 1
increases expression
ISO
deoxynivalenol results in increased expression of CXCR1 mRNA
CTD
PMID:22968694
NCBI chr 9:83,216,040...83,220,225
Ensembl chr 9:83,215,292...83,226,872
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Cxcr2
C-X-C motif chemokine receptor 2
increases expression
ISO
deoxynivalenol results in increased expression of CXCR2 mRNA
CTD
PMID:22968694
NCBI chr 9:83,178,645...83,185,017
Ensembl chr 9:83,183,808...83,188,602
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Cxcr4
C-X-C motif chemokine receptor 4
increases expression
ISO
deoxynivalenol results in increased expression of CXCR4 mRNA
CTD
PMID:22846391 PMID:27757495
NCBI chr13:42,630,383...42,634,288
Ensembl chr13:42,630,104...42,634,459
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Cyc1
cytochrome c-1
decreases expression
ISO
deoxynivalenol results in decreased expression of CYC1 protein
CTD
PMID:33890134
NCBI chr 7:109,947,750...109,950,142
Ensembl chr 7:109,947,766...109,950,657
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Cycs
cytochrome c, somatic
affects localization multiple interactions increases expression decreases expression increases activity
ISO
deoxynivalenol affects the localization of CYCS protein [deoxynivalenol co-treated with Aflatoxin B1] results in increased expression of CYCS protein deoxynivalenol results in increased expression of CYCS mRNA; deoxynivalenol results in increased expression of CYCS protein deoxynivalenol results in decreased expression of CYCS protein deoxynivalenol results in increased activity of CYCS protein
CTD
PMID:15976193 PMID:22269384 PMID:22846391 PMID:38763499
NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:80,982,668...80,984,816 Ensembl chr18:80,982,668...80,984,816
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Cyp11b2
cytochrome P450, family 11, subfamily b, polypeptide 2
increases expression
ISO
deoxynivalenol results in increased expression of CYP11B1 mRNA
CTD
PMID:22982764
NCBI chr 7:108,719,349...108,726,024
Ensembl chr 7:108,719,349...108,725,763
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Cyp11b3
cytochrome P450, family 11, subfamily b, polypeptide 3
increases expression
ISO
deoxynivalenol results in increased expression of CYP11B2 mRNA
CTD
PMID:22982764
NCBI chr 7:108,689,319...108,694,808
Ensembl chr 7:108,689,165...108,694,921
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Cyp17a1
cytochrome P450, family 17, subfamily a, polypeptide 1
increases expression
ISO
deoxynivalenol results in increased expression of CYP17A1 mRNA
CTD
PMID:22982764
NCBI chr 1:255,476,861...255,484,547
Ensembl chr 1:255,476,861...255,482,974
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Cyp19a1
cytochrome P450, family 19, subfamily a, polypeptide 1
decreases expression
ISO
deoxynivalenol results in decreased expression of CYP19A1 mRNA
CTD
PMID:22982764
NCBI chr 8:63,449,148...63,476,534
Ensembl chr 8:63,449,148...63,476,917
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Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
increases expression multiple interactions
ISO
deoxynivalenol results in increased expression of CYP1A1 mRNA 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of CYP1A1 mRNA]]; 6-formylindolo(3,2-b)carbazole promotes the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of CYP1A1 mRNA]]; sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of CYP1A1 mRNA]
CTD
PMID:22982764 PMID:35381244
NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
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Cyp1b1
cytochrome P450, family 1, subfamily b, polypeptide 1
decreases expression
ISO
deoxynivalenol results in decreased expression of CYP1B1 mRNA
CTD
PMID:20702593
NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142
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Cyp27a1
cytochrome P450, family 27, subfamily a, polypeptide 1
decreases expression
ISO
deoxynivalenol results in decreased expression of CYP27A1 protein
CTD
PMID:39638853
NCBI chr 9:83,712,402...83,743,222
Ensembl chr 9:83,713,293...83,743,215
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Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
increases expression
ISO
deoxynivalenol results in increased expression of CYP2E1 mRNA; deoxynivalenol results in increased expression of CYP2E1 protein
CTD
PMID:39147090
NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495
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Cyp2w1
cytochrome P450, family 2, subfamily w, polypeptide 1
decreases expression
ISO
deoxynivalenol results in decreased expression of CYP2W1 protein
CTD
PMID:39638853
NCBI chr12:20,405,400...20,410,282
Ensembl chr12:20,405,400...20,410,282
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Cyp3a2
cytochrome P450, family 3, subfamily a, polypeptide 2
affects expression multiple interactions
ISO
deoxynivalenol affects the expression of CYP3A4 mRNA [deoxynivalenol co-treated with Zearalenone] affects the expression of CYP3A4 mRNA; [deoxynivalenol co-treated with Zearalenone] results in decreased expression of CYP3A4 protein; [deoxynivalenol co-treated with Zearalenone] results in increased expression of CYP3A4 mRNA; [deoxynivalenol co-treated with Zearalenone] results in increased expression of CYP3A4 protein
CTD
PMID:28865950 PMID:28935499
NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857
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Cyp4f1
cytochrome P450, family 4, subfamily f, polypeptide 1
decreases expression
ISO
deoxynivalenol results in decreased expression of CYP4F12 protein
CTD
PMID:39638853
NCBI chr 7:12,661,357...12,672,952
Ensembl chr 7:12,661,359...12,672,612
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Cyp4f18
cytochrome P450, family 4, subfamily f, polypeptide 18
multiple interactions
ISO
[deoxynivalenol co-treated with Zearalenone] results in decreased expression of CYP4F3 mRNA; [deoxynivalenol co-treated with Zearalenone] results in increased expression of CYP4F3 mRNA
CTD
PMID:28865950 PMID:28935499
NCBI chr16:17,797,558...17,838,958
Ensembl chr16:17,740,001...17,838,958
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Cyp51
cytochrome P450, family 51
decreases expression
ISO
deoxynivalenol results in decreased expression of CYP51A1 protein
CTD
PMID:39638853
NCBI chr 4:30,991,693...31,010,147
Ensembl chr 4:30,991,613...31,010,450
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Cytl1
cytokine like 1
decreases expression
ISO
deoxynivalenol results in decreased expression of CYTL1 mRNA
CTD
PMID:31863870
NCBI chr14:77,278,635...77,283,645
Ensembl chr14:77,278,636...77,283,645
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Dag1
dystroglycan 1
decreases expression
ISO
deoxynivalenol results in decreased expression of DAG1 protein
CTD
PMID:39638853
NCBI chr 8:117,769,517...117,834,347
Ensembl chr 8:117,769,517...117,782,199
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Dbi
diazepam binding inhibitor
decreases expression
ISO
deoxynivalenol results in decreased expression of DBI protein
CTD
PMID:39638853
NCBI chr13:33,794,231...33,802,632
Ensembl chr13:33,759,845...33,821,450
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Dcaf13
DDB1 and CUL4 associated factor 13
increases expression
ISO
deoxynivalenol results in increased expression of DCAF13 protein
CTD
PMID:39638853
NCBI chr 7:72,045,828...72,081,039
Ensembl chr 7:72,045,872...72,083,629
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Ddb2
damage specific DNA binding protein 2
increases expression
ISO
deoxynivalenol results in increased expression of DDB2 mRNA
CTD
PMID:31863870
NCBI chr 3:97,640,923...97,667,617
Ensembl chr 3:97,640,579...97,664,066
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Ddit3
DNA-damage inducible transcript 3
increases expression decreases expression
ISO
deoxynivalenol results in increased expression of DDIT3 mRNA deoxynivalenol results in decreased expression of DDIT3 mRNA
CTD
PMID:22846391 PMID:23253260 PMID:30169763
NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509
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Ddit4
DNA-damage-inducible transcript 4
decreases expression
ISO
deoxynivalenol results in decreased expression of DDIT4 mRNA
CTD
PMID:31863870
NCBI chr20:28,434,938...28,437,037
Ensembl chr20:28,434,944...28,437,037
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Ddrgk1
DDRGK domain containing 1
increases expression
ISO
deoxynivalenol results in increased expression of DDRGK1 protein
CTD
PMID:39638853
NCBI chr 3:138,315,006...138,336,691
Ensembl chr 3:138,315,282...138,335,766
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Ddx17
DEAD-box helicase 17
increases expression
ISO
deoxynivalenol results in increased expression of DDX17 protein
CTD
PMID:39638853
NCBI chr 7:112,971,522...112,989,747
Ensembl chr 7:112,971,523...112,989,747
G
Ddx18
DEAD-box helicase 18
increases expression
ISO
deoxynivalenol results in increased expression of DDX18 protein
CTD
PMID:39638853
NCBI chr13:35,282,391...35,296,038
Ensembl chr13:35,282,467...35,295,972
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Ddx21
DExD-box helicase 21
decreases phosphorylation increases expression
ISO
deoxynivalenol results in decreased phosphorylation of DDX21 protein deoxynivalenol results in increased expression of DDX21 protein
CTD
PMID:23352502 PMID:23811945 PMID:39638853
NCBI chr20:31,077,044...31,097,238
Ensembl chr20:31,077,045...31,097,238
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Ddx24
DEAD-box helicase 24
increases expression
ISO
deoxynivalenol results in increased expression of DDX24 protein
CTD
PMID:39638853
NCBI chr 6:128,329,554...128,346,818
Ensembl chr 6:128,329,554...128,349,625
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Ddx27
DEAD-box helicase 27
increases expression
ISO
deoxynivalenol results in increased expression of DDX27 protein
CTD
PMID:39638853
NCBI chr 3:176,163,220...176,182,418
Ensembl chr 3:176,163,203...176,182,410
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Ddx39a
DExD-box helicase 39A
increases expression
ISO
deoxynivalenol results in increased expression of DDX39A mRNA
CTD
PMID:31863870
NCBI chr19:41,323,465...41,331,413
Ensembl chr19:41,322,836...41,332,306
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Ddx42
DEAD-box helicase 42
increases expression
ISO
deoxynivalenol results in increased expression of DDX42 protein
CTD
PMID:39638853
NCBI chr10:91,648,719...91,680,730
Ensembl chr10:91,648,248...91,680,729
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Ddx46
DEAD-box helicase 46
increases expression
ISO
deoxynivalenol results in increased expression of DDX46 protein
CTD
PMID:39638853
NCBI chr17:8,947,237...8,993,705
Ensembl chr17:8,947,237...8,990,247
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Ddx5
DEAD-box helicase 5
increases expression
ISO
deoxynivalenol results in increased expression of DDX5 protein
CTD
PMID:39638853
NCBI chr10:92,224,393...92,231,928
Ensembl chr10:92,224,395...92,231,300
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Ddx50
DExD-box helicase 50
increases expression
ISO
deoxynivalenol results in increased expression of DDX50 protein
CTD
PMID:39638853
NCBI chr20:31,104,354...31,133,652
Ensembl chr20:31,104,354...31,133,652
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Ddx52
DExD-box helicase 52
increases expression
ISO
deoxynivalenol results in increased expression of DDX52 mRNA
CTD
PMID:31863870
NCBI chr10:69,322,062...69,344,856
Ensembl chr10:69,322,114...69,428,714
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Ddx54
DEAD-box helicase 54
increases expression
ISO
deoxynivalenol results in increased expression of DDX54 protein
CTD
PMID:39638853
NCBI chr12:41,595,298...41,610,560
Ensembl chr12:41,595,555...41,611,053
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Ddx56
DEAD-box helicase 56
increases expression
ISO
deoxynivalenol results in increased expression of DDX56 protein
CTD
PMID:39638853
NCBI chr14:85,325,942...85,336,262
Ensembl chr14:85,325,942...85,336,262
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Deptor
DEP domain containing MTOR-interacting protein
decreases expression
ISO
deoxynivalenol results in decreased expression of DEPTOR mRNA
CTD
PMID:31863870
NCBI chr 7:88,404,745...88,574,065
Ensembl chr 7:88,404,620...88,574,041
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Dffa
DNA fragmentation factor subunit alpha
decreases phosphorylation
ISO
deoxynivalenol results in decreased phosphorylation of DFFA protein
CTD
PMID:23811945
NCBI chr 5:164,823,807...164,836,729
Ensembl chr 5:164,823,807...164,836,728
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Dgkg
diacylglycerol kinase, gamma
multiple interactions
ISO
[Selenomethionine co-treated with deoxynivalenol] results in increased expression of DGKG mRNA
CTD
PMID:38040082
NCBI chr11:91,888,957...92,083,715
Ensembl chr11:91,888,782...92,082,105
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Dgki
diacylglycerol kinase, iota
multiple interactions
ISO
[Selenomethionine co-treated with deoxynivalenol] results in increased expression of DGKI mRNA
CTD
PMID:38040082
NCBI chr 4:66,377,897...66,839,790
Ensembl chr 4:66,387,126...66,990,832
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Dhrs2
dehydrogenase/reductase 2
decreases expression
ISO
deoxynivalenol results in decreased expression of DHRS2 protein
CTD
PMID:39638853
NCBI chr15:32,658,855...32,673,591
Ensembl chr15:32,659,223...32,673,588
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Dhx33
DEAH-box helicase 33
increases expression
ISO
deoxynivalenol results in increased expression of DHX33 protein
CTD
PMID:39638853
NCBI chr10:56,206,680...56,223,189
Ensembl chr10:56,206,680...56,223,143
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Dhx37
DEAH-box helicase 37
increases expression
ISO
deoxynivalenol results in increased expression of DHX37 protein
CTD
PMID:39638853
NCBI chr12:36,856,119...36,876,245
Ensembl chr12:36,849,701...36,876,240
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Diablo
diablo, IAP-binding mitochondrial protein
increases expression
ISO
deoxynivalenol results in increased expression of DIABLO protein
CTD
PMID:39638853
NCBI chr12:38,716,668...38,731,285
Ensembl chr12:38,716,668...38,731,265
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Dimt1
DIM1 rRNA methyltransferase and ribosome maturation factor
increases expression
ISO
deoxynivalenol results in increased expression of DIMT1 protein
CTD
PMID:39638853
NCBI chr 2:40,076,622...40,101,792
Ensembl chr 2:40,076,570...40,101,787
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Dkc1
dyskerin pseudouridine synthase 1
decreases phosphorylation increases expression
ISO
deoxynivalenol results in decreased phosphorylation of DKC1 protein deoxynivalenol results in increased expression of DKC1 protein
CTD
PMID:23811945 PMID:39638853
NCBI chr X:157,751,651...157,757,796
Ensembl chr Y:380,743...385,405 Ensembl chr X:380,743...385,405
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Dnah10
dynein, axonemal, heavy chain 10
affects phosphorylation
ISO
deoxynivalenol affects the phosphorylation of DNAH10 protein
CTD
PMID:23811945
NCBI chr12:37,484,444...37,607,810
Ensembl chr12:37,472,813...37,640,860
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Dnaja1
DnaJ heat shock protein family (Hsp40) member A1
increases expression decreases expression
ISO
deoxynivalenol results in increased expression of DNAJA1 mRNA deoxynivalenol results in decreased expression of DNAJA1 protein
CTD
PMID:15371230 PMID:33890134
NCBI chr 5:60,638,404...60,649,315
Ensembl chr 5:60,638,410...60,650,160
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Dnajc1
DnaJ heat shock protein family (Hsp40) member C1
increases expression
ISO
deoxynivalenol results in increased expression of DNAJC1 mRNA
CTD
PMID:24247028
NCBI chr17:85,863,651...86,020,954
Ensembl chr17:85,863,651...86,020,432
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Dnajc3
DnaJ heat shock protein family (Hsp40) member C3
multiple interactions decreases expression
ISO
deoxynivalenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of DNAJC3 mRNA] deoxynivalenol results in decreased expression of DNAJC3 mRNA
CTD
PMID:10652249
NCBI chr15:102,432,667...102,475,643
Ensembl chr15:102,432,663...102,475,643
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Dnajc5
DnaJ heat shock protein family (Hsp40) member C5
increases phosphorylation
ISO
deoxynivalenol results in increased phosphorylation of DNAJC5 protein
CTD
PMID:23352502
NCBI chr 3:188,999,508...189,033,455
Ensembl chr 3:188,999,470...189,034,089
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Dnajc7
DnaJ heat shock protein family (Hsp40) member C7
increases expression
ISO
deoxynivalenol results in increased expression of DNAJC7 protein
CTD
PMID:39638853
NCBI chr10:86,018,977...86,055,419
Ensembl chr10:86,018,961...86,055,489
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Dnmt1
DNA methyltransferase 1
affects phosphorylation increases expression
ISO EXP
deoxynivalenol affects the phosphorylation of DNMT1 protein deoxynivalenol results in increased expression of DNMT1 mRNA; deoxynivalenol results in increased expression of DNMT1 protein
CTD
PMID:23352502 PMID:23811945 PMID:32738333
NCBI chr 8:27,716,797...27,763,405
Ensembl chr 8:27,716,797...27,763,119
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Dnmt3a
DNA methyltransferase 3 alpha
increases expression
EXP
deoxynivalenol results in increased expression of DNMT3A mRNA; deoxynivalenol results in increased expression of DNMT3A protein
CTD
PMID:32738333
NCBI chr 6:32,507,316...32,621,678
Ensembl chr 6:32,512,070...32,614,970
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Dnttip2
deoxynucleotidyltransferase, terminal, interacting protein 2
increases expression
ISO
deoxynivalenol results in increased expression of DNTTIP2 mRNA; deoxynivalenol results in increased expression of DNTTIP2 protein
CTD
PMID:31863870 PMID:39638853
NCBI chr 2:213,058,975...213,071,020
Ensembl chr 2:213,058,962...213,071,016
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Dpep1
dipeptidase 1
decreases expression
ISO
deoxynivalenol results in decreased expression of DPEP1 protein
CTD
PMID:39638853
NCBI chr19:68,118,270...68,143,781
Ensembl chr19:68,118,453...68,143,775
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Dpysl2
dihydropyrimidinase-like 2
decreases expression
ISO
deoxynivalenol results in decreased expression of DPYSL2 protein
CTD
PMID:39638853
NCBI chr15:45,181,041...45,287,065
Ensembl chr15:45,181,041...45,287,065
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Dsc1
desmocollin 1
increases expression
ISO
deoxynivalenol results in increased expression of DSC1 protein
CTD
PMID:33890134
NCBI chr18:11,774,711...11,831,868
Ensembl chr18:11,775,010...11,803,522
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Dusp1
dual specificity phosphatase 1
increases expression multiple interactions
ISO
deoxynivalenol results in increased expression of DUSP1 mRNA; deoxynivalenol results in increased expression of DUSP1 protein Fatty Acids, Omega-3 promotes the reaction [deoxynivalenol results in increased expression of DUSP1 mRNA] [deoxynivalenol results in increased expression of DUSP1 protein] which results in decreased activity of MAPK8 protein; [deoxynivalenol results in increased expression of DUSP1 protein] which results in decreased activity of MAPK9 protein
CTD
PMID:15371230 PMID:15681167 PMID:20708668
NCBI chr10:17,184,853...17,187,646
Ensembl chr10:17,184,823...17,187,644
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Dusp6
dual specificity phosphatase 6
decreases expression
ISO
deoxynivalenol results in decreased expression of DUSP6 mRNA
CTD
PMID:24247028
NCBI chr 7:35,979,502...35,983,834
Ensembl chr 7:35,977,921...35,983,833
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Dusp8
dual specificity phosphatase 8
increases expression
ISO
deoxynivalenol results in increased expression of DUSP8 mRNA
CTD
PMID:23792671
NCBI chr 1:206,596,912...206,613,728
Ensembl chr 1:206,598,942...206,612,441
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Dusp9
dual specificity phosphatase 9
decreases expression
ISO
deoxynivalenol results in decreased expression of DUSP9 protein
CTD
PMID:39638853
NCBI chr X:156,503,237...156,507,162
Ensembl chr X:156,503,190...156,507,161
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Dync1li1
dynein cytoplasmic 1 light intermediate chain 1
increases phosphorylation
ISO
deoxynivalenol results in increased phosphorylation of DYNC1LI1 protein
CTD
PMID:23352502
NCBI chr 8:123,254,823...123,288,496
Ensembl chr 8:123,254,859...123,289,167
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Ebna1bp2
EBNA1 binding protein 2
increases expression
ISO
deoxynivalenol results in increased expression of EBNA1BP2 protein
CTD
PMID:39638853
NCBI chr 5:137,433,534...137,438,100
Ensembl chr 5:137,433,226...137,438,637
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Ece1
endothelin converting enzyme 1
decreases expression
ISO
deoxynivalenol results in decreased expression of ECE1 protein
CTD
PMID:39638853
NCBI chr 5:155,361,031...155,462,723
Ensembl chr 5:155,360,639...155,462,719
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Eci2
enoyl-CoA delta isomerase 2
decreases expression
ISO
deoxynivalenol results in decreased expression of ECI2 protein
CTD
PMID:39638853
NCBI chr17:30,056,274...30,092,169
Ensembl chr17:30,076,524...30,092,161
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Ecm1
extracellular matrix protein 1
decreases expression
ISO
deoxynivalenol results in decreased expression of ECM1 mRNA
CTD
PMID:31863870
NCBI chr 2:185,976,439...185,981,656
Ensembl chr 2:185,976,440...185,981,606
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Ect2
epithelial cell transforming 2
increases expression
ISO
deoxynivalenol results in increased expression of ECT2 mRNA
CTD
PMID:31863870
NCBI chr 2:111,904,522...111,966,786
Ensembl chr 2:111,904,522...111,966,626
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Edf1
endothelial differentiation-related factor 1
increases expression
ISO
deoxynivalenol results in increased expression of EDF1 protein
CTD
PMID:39638853
NCBI chr 3:28,764,906...28,779,499
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Eea1
early endosome antigen 1
increases expression
ISO
deoxynivalenol results in increased expression of EEA1 protein
CTD
PMID:39638853
NCBI chr 7:32,441,281...32,608,808
Ensembl chr 7:32,441,272...32,608,476
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Eef1b2
eukaryotic translation elongation factor 1 beta 2
decreases phosphorylation
ISO
deoxynivalenol results in decreased phosphorylation of EEF1B2 protein
CTD
PMID:23352502
NCBI chr 9:72,074,091...72,076,591
Ensembl chr 9:72,073,802...72,076,589
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Eef1d
eukaryotic translation elongation factor 1 delta
increases phosphorylation
ISO
deoxynivalenol results in increased phosphorylation of EEF1D protein
CTD
PMID:23811945
NCBI chr 7:109,462,645...109,478,021
Ensembl chr 7:109,462,646...109,489,531
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Egf
epidermal growth factor
increases expression
ISO
deoxynivalenol results in increased expression of EGF mRNA
CTD
PMID:27757495
NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:220,893,660...220,976,297
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Egfr
epidermal growth factor receptor
decreases expression
ISO
deoxynivalenol results in decreased expression of EGFR protein
CTD
PMID:33890134 PMID:39638853
NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358
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Egr1
early growth response 1
increases expression multiple interactions
ISO
[deoxynivalenol results in increased expression of EGR1 protein] which results in increased expression of CXCL8 protein; deoxynivalenol results in increased expression of EGR1 mRNA; deoxynivalenol results in increased expression of EGR1 protein ATF3 protein affects the reaction [deoxynivalenol results in increased expression of EGR1 protein]; deoxynivalenol results in increased expression of and results in increased phosphorylation of EGR1 protein; EGR1 protein affects the reaction [deoxynivalenol results in increased expression of CDKN1A protein]; EGR1 protein promotes the reaction [deoxynivalenol results in increased expression of PPARG mRNA]
CTD
PMID:17707346 PMID:18485432 PMID:19360757 PMID:30286430 PMID:33890134
NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,736,838...26,740,843
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Ehd1
EH-domain containing 1
decreases expression
ISO
deoxynivalenol results in decreased expression of EHD1 protein
CTD
PMID:39638853
NCBI chr 1:213,009,113...213,031,488
Ensembl chr 1:213,008,049...213,031,485
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Eid2
EP300 interacting inhibitor of differentiation 2
increases expression
ISO
deoxynivalenol results in increased expression of EID2 mRNA
CTD
PMID:31863870
NCBI chr 1:92,665,837...92,667,162
Ensembl chr 1:92,665,481...92,675,307
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Eif1
eukaryotic translation initiation factor 1
increases expression
ISO
deoxynivalenol results in increased expression of EIF1 protein
CTD
PMID:39638853
NCBI chr10:85,747,064...85,749,447
Ensembl chr 5:25,895,968...25,896,654 Ensembl chr10:25,895,968...25,896,654
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Eif2a
eukaryotic translation initiation factor 2A
increases phosphorylation
ISO
deoxynivalenol results in increased phosphorylation of EIF2A protein
CTD
PMID:20682335
NCBI chr 2:144,911,247...144,944,705
Ensembl chr 2:144,911,153...144,945,201
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Eif2ak2
eukaryotic translation initiation factor 2-alpha kinase 2
decreases expression affects response to substance multiple interactions
ISO
deoxynivalenol results in decreased expression of EIF2AK2 mRNA EIF2AK2 protein affects the susceptibility to deoxynivalenol EIF2AK2 protein affects the reaction [deoxynivalenol results in increased activity of RELA protein]; EIF2AK2 protein affects the reaction [deoxynivalenol results in increased expression of CXCL8 mRNA]
CTD
PMID:17090620 PMID:18599499 PMID:22491426
NCBI chr 6:21,941,147...21,977,115
Ensembl chr 6:21,952,631...21,977,116
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Eif2b4
eukaryotic translation initiation factor 2B subunit delta
increases expression
ISO
deoxynivalenol results in increased expression of EIF2B4 mRNA
CTD
PMID:31863870
NCBI chr 6:30,903,148...30,908,803
Ensembl chr 6:30,903,219...30,908,800
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Eif2s2
eukaryotic translation initiation factor 2 subunit beta
affects expression
ISO
deoxynivalenol affects the expression of EIF2S2 mRNA
CTD
PMID:24247028
NCBI chr 3:163,834,846...163,855,733
Ensembl chr 3:163,834,851...163,855,570
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Eif3a
eukaryotic translation initiation factor 3, subunit A
increases expression
ISO
deoxynivalenol results in increased expression of EIF3A protein
CTD
PMID:39638853
NCBI chr 1:269,888,730...269,925,785
Ensembl chr 1:269,888,615...269,919,025
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Eif3b
eukaryotic translation initiation factor 3, subunit B
affects phosphorylation increases expression
ISO
deoxynivalenol affects the phosphorylation of EIF3B protein deoxynivalenol results in increased expression of EIF3B protein
CTD
PMID:23811945 PMID:39638853
NCBI chr12:19,310,308...19,334,768
Ensembl chr12:19,310,311...19,334,939
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Eif3c
eukaryotic translation initiation factor 3, subunit C
affects phosphorylation
ISO
deoxynivalenol affects the phosphorylation of EIF3C protein
CTD
PMID:23811945
NCBI chr 1:190,565,183...190,583,067
Ensembl chr 1:190,565,184...190,583,067
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Eif3d
eukaryotic translation initiation factor 3, subunit D
increases expression
ISO
deoxynivalenol results in increased expression of EIF3D protein
CTD
PMID:39638853
NCBI chr 7:111,420,351...111,432,761
Ensembl chr 7:111,420,351...111,432,740
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Eif3e
eukaryotic translation initiation factor 3 subunit E
increases expression
ISO
deoxynivalenol results in increased expression of EIF3E protein
CTD
PMID:39638853
NCBI chr 7:76,224,567...76,257,346
Ensembl chr 7:76,224,568...76,257,785
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Eif3f
eukaryotic translation initiation factor 3, subunit F
increases expression
ISO
deoxynivalenol results in increased expression of EIF3F protein
CTD
PMID:39638853
NCBI chr 1:172,369,062...172,378,043
Ensembl chr 1:172,369,062...172,378,041
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Eif3i
eukaryotic translation initiation factor 3, subunit I
increases expression
ISO
deoxynivalenol results in increased expression of EIF3I protein
CTD
PMID:39638853
NCBI chr 5:147,219,457...147,226,910
Ensembl chr 5:147,219,366...147,241,232
G
Eif3j
eukaryotic translation initiation factor 3, subunit J
increases expression
ISO
deoxynivalenol results in increased expression of EIF3J protein
CTD
PMID:39638853
NCBI chr 3:129,438,715...129,460,953
Ensembl chr 3:129,438,722...129,462,246
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Eif4a3
eukaryotic translation initiation factor 4A3
increases expression
ISO
deoxynivalenol results in increased expression of EIF4A3 protein
CTD
PMID:39638853
NCBI chr10:105,047,567...105,057,561
Ensembl chr10:105,047,568...105,058,207
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Eif4ebp1
eukaryotic translation initiation factor 4E binding protein 1
increases phosphorylation
ISO
deoxynivalenol results in increased phosphorylation of EIF4EBP1 protein
CTD
PMID:23352502
NCBI chr16:71,495,457...71,508,845
Ensembl chr16:71,487,930...71,508,874
G
Eif4g1
eukaryotic translation initiation factor 4 gamma 1
increases phosphorylation increases expression
ISO
deoxynivalenol results in increased phosphorylation of EIF4G1 protein deoxynivalenol results in increased expression of EIF4G1 protein
CTD
PMID:23352502 PMID:39638853
NCBI chr11:93,726,322...93,746,387
Ensembl chr11:93,726,322...93,746,367
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Eif4g2
eukaryotic translation initiation factor 4, gamma 2
increases expression
ISO
deoxynivalenol results in increased expression of EIF4G2 protein
CTD
PMID:39638853
NCBI chr 1:174,616,102...174,628,252
Ensembl chr 1:174,616,103...174,628,252
G
Eif5b
eukaryotic translation initiation factor 5B
affects phosphorylation increases expression
ISO
deoxynivalenol affects the phosphorylation of EIF5B protein deoxynivalenol results in increased expression of EIF5B protein
CTD
PMID:23811945 PMID:39638853
NCBI chr 9:47,718,706...47,773,289
Ensembl chr 9:47,718,706...47,778,583
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Eif6
eukaryotic translation initiation factor 6
increases expression
ISO
deoxynivalenol results in increased expression of EIF6 protein
CTD
PMID:39638853
NCBI chr 3:164,785,162...164,791,410
Ensembl chr 3:164,785,163...164,791,525
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Elavl1
ELAV like RNA binding protein 1
multiple interactions
ISO
[[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which affects the localization of ELAVL1 protein] which co-treated with deoxynivalenol] promotes the reaction [[ELAVL1 protein binds to ATF3 3' UTR] which results in increased stability of ATF3 mRNA]; [[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] affects the localization of ELAVL1 protein; [deoxynivalenol results in increased expression of ELAVL1 protein] which results in decreased degradation of CXCL8 mRNA; deoxynivalenol results in increased expression of and results in increased localization of ELAVL1 protein; ELAVL1 protein affects the reaction [[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of CXCL1 mRNA]; ELAVL1 protein affects the reaction [[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of CXCL8 mRNA]; ELAVL1 protein affects the reaction [deoxynivalenol results in increased expression of CXCL8 mRNA]; ELAVL1 protein affects the reaction [deoxynivalenol results in increased expression of CXCL8 protein]
CTD
PMID:19591856 PMID:22003189
NCBI chr12:7,441,699...7,482,625
Ensembl chr12:7,441,699...7,482,631
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Elk1
ETS transcription factor ELK1
increases expression
ISO
deoxynivalenol results in increased expression of ELK1 protein
CTD
PMID:33890134
NCBI chr X:3,692,367...3,709,252
Ensembl chr X:3,693,293...3,709,249
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Emc10
ER membrane protein complex subunit 10
decreases expression
ISO
deoxynivalenol results in decreased expression of EMC10 mRNA
CTD
PMID:31863870
NCBI chr 1:104,119,040...104,125,409
Ensembl chr 1:104,119,040...104,125,368
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Emg1
EMG1 N1-specific pseudouridine methyltransferase
increases expression
ISO
deoxynivalenol results in increased expression of EMG1 protein
CTD
PMID:39638853
NCBI chr 4:159,195,545...159,203,826
Ensembl chr 4:159,195,564...159,203,826
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Emilin1
elastin microfibril interfacer 1
decreases expression
ISO
deoxynivalenol results in decreased expression of EMILIN1 mRNA
CTD
PMID:31863870
NCBI chr 6:31,175,919...31,183,657
Ensembl chr 6:31,175,919...31,183,657
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Eng
endoglin
decreases expression
ISO
deoxynivalenol results in decreased expression of ENG mRNA
CTD
PMID:31863870
NCBI chr 3:36,332,190...36,370,324
Ensembl chr 3:36,326,202...36,370,933
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Engase
endo-beta-N-acetylglucosaminidase
increases expression
ISO
deoxynivalenol results in increased expression of ENGASE mRNA
CTD
PMID:23792671
NCBI chr10:104,205,753...104,218,416
Ensembl chr10:104,205,752...104,218,411
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Eno2
enolase 2
decreases expression
ISO
deoxynivalenol results in decreased expression of ENO2 protein
CTD
PMID:39638853
NCBI chr 4:159,258,371...159,267,220
Ensembl chr 4:159,258,371...159,267,220
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Ep300
E1A binding protein p300
multiple interactions increases expression
ISO
EP300 protein affects the reaction [deoxynivalenol results in increased expression of ATF3 protein alternative form] deoxynivalenol results in increased expression of EP300 protein
CTD
PMID:30286430
NCBI chr 7:114,987,857...115,058,652
Ensembl chr 7:114,946,982...115,058,574
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Ep400
E1A binding protein p400
decreases phosphorylation
ISO
deoxynivalenol results in decreased phosphorylation of EP400 protein
CTD
PMID:23352502
NCBI chr12:51,551,665...51,658,635
Ensembl chr12:51,551,695...51,658,634
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Epb41l2
erythrocyte membrane protein band 4.1-like 2
affects phosphorylation
ISO
deoxynivalenol affects the phosphorylation of EPB41L2 protein
CTD
PMID:23811945
NCBI chr 1:21,682,336...21,857,106
Ensembl chr 1:21,682,335...21,857,105
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Epha2
Eph receptor A2
increases expression
ISO
deoxynivalenol results in increased expression of EPHA2 protein
CTD
PMID:39638853
NCBI chr 5:158,888,629...158,917,100
Ensembl chr 5:158,888,629...158,917,234
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Ephx1
epoxide hydrolase 1
decreases expression
ISO
deoxynivalenol results in decreased expression of EPHX1 mRNA deoxynivalenol results in decreased expression of EPHX1 protein
CTD
PMID:15371230 PMID:39638853
NCBI chr13:95,246,079...95,275,852
Ensembl chr13:95,246,080...95,321,981
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Eppk1
epiplakin 1
decreases expression
ISO
deoxynivalenol results in decreased expression of EPPK1 protein
CTD
PMID:39638853
NCBI chr 7:109,697,607...109,718,468
Ensembl chr 7:109,697,607...109,718,468
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Ern1
endoplasmic reticulum to nucleus signaling 1
decreases expression increases expression
ISO
deoxynivalenol results in decreased expression of ERN1 mRNA deoxynivalenol results in increased expression of ERN1 protein
CTD
PMID:19336499 PMID:20682335
NCBI chr10:91,826,663...91,920,976
Ensembl chr10:91,830,428...91,920,791
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Esf1
ESF1 nucleolar pre-rRNA processing protein homolog
increases expression
ISO
deoxynivalenol results in increased expression of ESF1 protein
CTD
PMID:39638853
NCBI chr 3:147,908,405...147,961,567
Ensembl chr 3:147,908,405...147,961,485
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Esr1
estrogen receptor 1
multiple interactions increases phosphorylation
ISO
ESR1 promotes the reaction [deoxynivalenol results in increased expression of PGR mRNA]; ESR1 promotes the reaction [deoxynivalenol results in increased expression of TFF1 mRNA] deoxynivalenol results in increased phosphorylation of ESR1 protein
CTD
PMID:35588983
NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354
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Etnk1
ethanolamine kinase 1
increases expression
ISO
deoxynivalenol results in increased expression of ETNK1 mRNA
CTD
PMID:31863870
NCBI chr 4:177,857,001...177,901,278
Ensembl chr 4:177,856,960...177,924,721
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Evi2a
ecotropic viral integration site 2A
increases expression
ISO
deoxynivalenol results in increased expression of EVI2A mRNA
CTD
PMID:24247028
NCBI chr10:64,983,727...64,987,627
Ensembl chr10:64,983,705...64,999,516
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Evl
Enah/Vasp-like
affects phosphorylation
ISO
deoxynivalenol affects the phosphorylation of EVL protein
CTD
PMID:23811945
NCBI chr 6:133,238,547...133,358,730
Ensembl chr 6:133,238,547...133,358,729
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Exosc1
exosome component 1
increases expression
ISO
deoxynivalenol results in increased expression of EXOSC1 protein
CTD
PMID:39638853
NCBI chr 1:250,684,746...250,694,748
Ensembl chr 1:250,684,750...250,694,748
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Exosc10
exosome component 10
increases expression
ISO
deoxynivalenol results in increased expression of EXOSC10 protein
CTD
PMID:39638853
NCBI chr 5:164,278,414...164,302,067
Ensembl chr 5:164,278,440...164,302,067
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Exosc2
exosome component 2
increases expression
ISO
deoxynivalenol results in increased expression of EXOSC2 mRNA; deoxynivalenol results in increased expression of EXOSC2 protein
CTD
PMID:24247028 PMID:39638853
NCBI chr 3:35,360,652...35,370,948
Ensembl chr 3:35,360,666...35,371,373
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Exosc4
exosome component 4
increases expression
ISO
deoxynivalenol results in increased expression of EXOSC4 protein
CTD
PMID:39638853
NCBI chr 7:109,928,491...109,931,233
Ensembl chr 7:109,928,498...109,931,820
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Exosc7
exosome component 7
increases expression
ISO
deoxynivalenol results in increased expression of EXOSC7 protein
CTD
PMID:39638853
NCBI chr 8:131,650,988...131,676,399
Ensembl chr 8:131,651,050...131,696,825
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F11r
F11 receptor
decreases expression
ISO
deoxynivalenol results in decreased expression of F11R protein
CTD
PMID:39638853
NCBI chr13:86,406,229...86,429,819
Ensembl chr13:86,406,218...86,429,816
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F2
coagulation factor II, thrombin
decreases expression
ISO
deoxynivalenol results in decreased expression of F2 protein
CTD
PMID:39638853
NCBI chr 3:98,051,958...98,065,246
Ensembl chr 3:98,051,960...98,065,246
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F3
coagulation factor III, tissue factor
decreases expression
ISO
deoxynivalenol results in decreased expression of F3 mRNA
CTD
PMID:31863870
NCBI chr 2:212,511,675...212,523,375
Ensembl chr 2:212,511,680...212,523,369
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Fabp3
fatty acid binding protein 3
decreases expression
ISO
deoxynivalenol results in decreased expression of FABP3 mRNA
CTD
PMID:31863870
NCBI chr 5:147,936,027...147,942,870
Ensembl chr 5:147,936,119...147,942,881
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Fabp4
fatty acid binding protein 4
decreases expression
ISO
deoxynivalenol results in decreased expression of FABP4 mRNA
CTD
PMID:31863870
NCBI chr 2:93,488,251...93,492,961
Ensembl chr 2:93,488,271...93,492,972
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Fabp6
fatty acid binding protein 6
decreases expression
ISO
deoxynivalenol results in decreased expression of FABP6 mRNA
CTD
PMID:35224661
NCBI chr10:28,565,054...28,569,727
Ensembl chr10:28,565,054...28,573,058
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Fads2
fatty acid desaturase 2
decreases expression
ISO
deoxynivalenol results in decreased expression of FADS2 protein
CTD
PMID:39638853
NCBI chr 1:216,132,277...216,172,190
Ensembl chr 1:216,133,676...216,172,066
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Fam169a
family with sequence similarity 169, member A
decreases expression
ISO
deoxynivalenol results in decreased expression of FAM169A protein
CTD
PMID:39638853
NCBI chr 2:30,115,307...30,175,972
Ensembl chr 2:30,119,381...30,175,962
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Fam83d
family with sequence similarity 83, member D
increases expression
ISO
deoxynivalenol results in increased expression of FAM83D mRNA
CTD
PMID:31863870
NCBI chr 3:167,841,748...167,861,062
Ensembl chr 3:167,841,791...167,861,061
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Fas
Fas cell surface death receptor
multiple interactions increases expression
EXP
Bentonite inhibits the reaction [deoxynivalenol results in increased expression of FAS protein]; Charcoal inhibits the reaction [deoxynivalenol results in increased expression of FAS protein] deoxynivalenol results in increased expression of FAS mRNA
CTD
PMID:26115597
NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:241,205,935...241,246,104
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Faslg
Fas ligand
increases expression
ISO
deoxynivalenol results in increased expression of FASL mRNA
CTD
PMID:22968694
NCBI chr13:76,680,885...76,706,042
Ensembl chr13:76,688,243...76,695,503
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Fasn
fatty acid synthase
decreases expression
ISO
deoxynivalenol results in decreased expression of FASN protein
CTD
PMID:39638853
NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,570,413...106,588,583
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Fastkd2
FAST kinase domains 2
increases expression
ISO
deoxynivalenol results in increased expression of FASTKD2 mRNA; deoxynivalenol results in increased expression of FASTKD2 protein
CTD
PMID:31863870 PMID:39638853
NCBI chr 9:72,659,961...72,681,986
Ensembl chr 9:72,661,764...72,721,338
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Fbl
fibrillarin
increases expression
ISO
deoxynivalenol results in increased expression of FBL protein
CTD
PMID:39638853
NCBI chr 1:92,597,407...92,606,507
Ensembl chr 1:92,597,258...92,606,506
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Fbxo2
F-box protein 2
decreases expression
ISO
deoxynivalenol results in decreased expression of FBXO2 protein
CTD
PMID:39638853
NCBI chr 5:163,876,079...163,881,508
Ensembl chr 5:163,875,757...163,881,508
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Fbxo22
F-box protein 22
increases expression
ISO
deoxynivalenol results in increased expression of FBXO22 mRNA
CTD
PMID:31863870
NCBI chr 8:64,476,034...64,492,063
Ensembl chr 8:64,475,957...64,492,062
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Fbxo28
F-box protein 28
increases expression
ISO
deoxynivalenol results in increased expression of FBXO28 mRNA
CTD
PMID:31863870
NCBI chr13:96,527,667...96,553,138
Ensembl chr13:96,527,670...96,553,138
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Fcgrt
Fc gamma receptor and transporter
decreases expression
ISO
deoxynivalenol results in decreased expression of FCGRT protein
CTD
PMID:39638853
NCBI chr 1:104,710,902...104,720,685
Ensembl chr 1:104,710,909...104,720,532
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Fdft1
farnesyl diphosphate farnesyl transferase 1
decreases expression
ISO
deoxynivalenol results in decreased expression of FDFT1 protein
CTD
PMID:33890134 PMID:39638853
NCBI chr15:41,588,114...41,616,168
Ensembl chr15:41,588,117...41,616,168
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Fdps
farnesyl diphosphate synthase
decreases expression
ISO
deoxynivalenol results in decreased expression of FDPS protein
CTD
PMID:33890134 PMID:39638853
NCBI chr 2:176,795,192...176,804,816
Ensembl chr 2:176,795,192...176,807,136
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Fgfr4
fibroblast growth factor receptor 4
decreases expression
ISO
deoxynivalenol results in decreased expression of FGFR4 protein
CTD
PMID:39638853
NCBI chr17:9,466,686...9,481,423
Ensembl chr17:9,466,692...9,481,389
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Flna
filamin A
decreases phosphorylation increases phosphorylation
ISO
deoxynivalenol results in decreased phosphorylation of FLNA protein deoxynivalenol results in increased phosphorylation of FLNA protein
CTD
PMID:23811945
NCBI chr X:157,159,051...157,185,559
Ensembl chr X:157,159,051...157,182,343
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Fmnl1
formin-like 1
decreases phosphorylation
ISO
deoxynivalenol results in decreased phosphorylation of FMNL1 protein
CTD
PMID:23352502
NCBI chr10:88,615,290...88,643,411
Ensembl chr10:88,615,869...88,643,411
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Fmod
fibromodulin
decreases expression
ISO
deoxynivalenol results in decreased expression of FMOD mRNA
CTD
PMID:31863870
NCBI chr13:48,045,567...48,056,184
Ensembl chr13:47,990,774...48,056,183
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Fn1
fibronectin 1
decreases expression
ISO
deoxynivalenol results in decreased expression of FN1 mRNA; deoxynivalenol results in decreased expression of FN1 protein
CTD
PMID:31863870 PMID:39638853
NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137
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Fn3k
fructosamine 3 kinase
decreases expression
ISO
deoxynivalenol results in decreased expression of FN3K protein
CTD
PMID:39638853
NCBI chr10:107,198,566...107,214,176
Ensembl chr10:107,198,892...107,214,175
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Fnbp1
formin binding protein 1
decreases expression
ISO
deoxynivalenol results in decreased expression of FNBP1 mRNA
CTD
PMID:24247028
NCBI chr 3:34,706,814...34,826,770
Ensembl chr 3:34,706,814...34,822,117
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Fndc3b
fibronectin type III domain containing 3B
increases expression
ISO
deoxynivalenol results in increased expression of FNDC3B protein
CTD
PMID:39638853
NCBI chr 2:112,240,108...112,546,113
Ensembl chr 2:112,243,202...112,546,306
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Fos
Fos proto-oncogene, AP-1 transcription factor subunit
increases expression multiple interactions affects activity
ISO
deoxynivalenol results in increased expression of FOS mRNA deoxynivalenol inhibits the reaction [Cadmium Chloride results in decreased expression of FOS mRNA] Celecoxib inhibits the reaction [deoxynivalenol results in increased expression of FOS protein] deoxynivalenol affects the activity of FOS protein deoxynivalenol results in increased expression of FOS mRNA; deoxynivalenol results in increased expression of FOS protein
CTD
PMID:10662601 PMID:15371230 PMID:15681167 PMID:19360757 PMID:21873375 PMID:22968694 PMID:24937323 PMID:32416088 PMID:33309878 PMID:35314294 More...
NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598
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Fosb
FosB proto-oncogene, AP-1 transcription factor subunit
affects activity multiple interactions increases expression
ISO
deoxynivalenol affects the activity of FOSB protein [Cadmium Chloride co-treated with deoxynivalenol] results in increased expression of FOSB mRNA deoxynivalenol results in increased expression of FOSB mRNA
CTD
PMID:10662601 PMID:33309878
NCBI chr 1:88,082,324...88,089,506
Ensembl chr 1:88,082,127...88,089,477
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Fosl1
FOS like 1, AP-1 transcription factor subunit
multiple interactions
ISO
[Cadmium Chloride co-treated with deoxynivalenol] results in increased expression of FOSL1 mRNA
CTD
PMID:33309878
NCBI chr 1:212,183,885...212,192,391
Ensembl chr 1:212,183,833...212,192,391
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Fosl2
FOS like 2, AP-1 transcription factor subunit
multiple interactions increases expression affects activity
ISO
Fatty Acids, Omega-3 inhibits the reaction [deoxynivalenol results in increased expression of FOSL2 mRNA] deoxynivalenol results in increased expression of FOSL2 mRNA; deoxynivalenol results in increased expression of FOSL2 protein [Cadmium Chloride co-treated with deoxynivalenol] results in increased expression of FOSL2 mRNA deoxynivalenol affects the activity of FOSL2 protein
CTD
PMID:10662601 PMID:15371230 PMID:15681167 PMID:33309878 PMID:33890134
NCBI chr 6:30,017,952...30,039,269
Ensembl chr 6:30,021,916...30,039,406
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Foxo1
forkhead box O1
increases phosphorylation
ISO
deoxynivalenol results in increased phosphorylation of FOXO1 protein
CTD
PMID:15976193
NCBI chr 2:138,462,974...138,541,420
Ensembl chr 2:138,462,697...138,541,419
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Foxo3
forkhead box O3
affects response to substance increases expression multiple interactions
ISO
FOXO3A affects the susceptibility to deoxynivalenol deoxynivalenol results in increased expression of FOXO3A mRNA Acetylcysteine inhibits the reaction [deoxynivalenol affects the localization of and results in increased activity of FOXO3A protein]; deoxynivalenol affects the localization of and results in increased activity of FOXO3A protein; pyrazolanthrone inhibits the reaction [deoxynivalenol affects the localization of FOXO3A protein]
CTD
PMID:30169763
NCBI chr20:47,251,968...47,348,254
Ensembl chr20:47,255,878...47,346,845
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Foxp3
forkhead box P3
increases expression
ISO
deoxynivalenol results in increased expression of FOXP3 mRNA
CTD
PMID:27757495
NCBI chr X:17,580,380...17,601,181
Ensembl chr X:17,580,380...17,595,894
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Fras1
Fraser extracellular matrix complex subunit 1
decreases expression
ISO
deoxynivalenol results in decreased expression of FRAS1 protein
CTD
PMID:39638853
NCBI chr14:13,095,370...13,506,895
Ensembl chr14:13,095,370...13,504,664
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Ftsj3
FtsJ RNA 2'-O-methyltransferase 3
increases expression
ISO
deoxynivalenol results in increased expression of FTSJ3 protein
CTD
PMID:39638853
NCBI chr10:91,680,735...91,687,475
Ensembl chr10:91,680,753...91,687,179
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Fubp1
far upstream element binding protein 1
increases expression
ISO
deoxynivalenol results in increased expression of FUBP1 protein
CTD
PMID:39638853
NCBI chr 2:243,819,529...243,846,544
Ensembl chr 2:243,819,218...243,846,428
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Fuca1
alpha-L-fucosidase 1
decreases expression
ISO
deoxynivalenol results in decreased expression of FUCA1 mRNA
CTD
PMID:31863870
NCBI chr 5:153,436,262...153,453,512
Ensembl chr 5:153,436,248...153,453,511
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Fus
Fus RNA binding protein
increases expression
ISO
deoxynivalenol results in increased expression of FUS protein
CTD
PMID:39638853
NCBI chr 1:192,007,011...192,020,887
Ensembl chr 1:192,007,006...192,020,884
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Fut1
fucosyltransferase 1
decreases expression
ISO
deoxynivalenol results in decreased expression of FUT1 mRNA
CTD
PMID:26763390
NCBI chr 1:105,223,399...105,226,817
Ensembl chr 1:105,223,390...105,227,513
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G3bp1
G3BP stress granule assembly factor 1
decreases phosphorylation increases phosphorylation
ISO
deoxynivalenol results in decreased phosphorylation of G3BP1 protein deoxynivalenol results in increased phosphorylation of G3BP1 protein
CTD
PMID:23352502 PMID:23811945
NCBI chr10:40,087,533...40,120,931
Ensembl chr10:40,087,533...40,120,931
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G3bp2
G3BP stress granule assembly factor 2
decreases phosphorylation
ISO
deoxynivalenol results in decreased phosphorylation of G3BP2 protein
CTD
PMID:23352502
NCBI chr14:16,216,684...16,304,828
Ensembl chr14:16,248,744...16,304,823
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Gabpa
GA binding protein transcription factor subunit alpha
decreases expression
ISO
deoxynivalenol results in decreased expression of GABPA protein
CTD
PMID:33890134
NCBI chr11:37,375,040...37,404,060
Ensembl chr11:37,375,084...37,404,059
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Gadd45a
growth arrest and DNA-damage-inducible, alpha
increases expression
ISO
deoxynivalenol results in increased expression of GADD45A mRNA
CTD
PMID:30169763 PMID:31863870
NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:97,484,502...97,486,807
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Galk1
galactokinase 1
decreases expression
ISO
deoxynivalenol results in decreased expression of GALK1 protein
CTD
PMID:39638853
NCBI chr10:101,742,067...101,746,244
Ensembl chr10:101,735,061...101,746,258
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Galm
galactose mutarotase
decreases expression
ISO
deoxynivalenol results in decreased expression of GALM protein
CTD
PMID:39638853
NCBI chr 6:20,589,775...20,641,516
Ensembl chr 6:20,589,776...20,644,417
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Galnt1
polypeptide N-acetylgalactosaminyltransferase 1
decreases expression
ISO
deoxynivalenol results in decreased expression of GALNT1 mRNA
CTD
PMID:31863870
NCBI chr18:15,763,697...15,843,598
Ensembl chr18:15,764,277...15,843,588
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Galp
galanin-like peptide
multiple interactions increases expression
EXP
GALP protein promotes the reaction [deoxynivalenol results in increased expression of IL11 protein]; GALP protein promotes the reaction [deoxynivalenol results in increased expression of IL1B protein]; GALP protein promotes the reaction [deoxynivalenol results in increased expression of IL6 protein] deoxynivalenol results in increased expression of GALP mRNA; deoxynivalenol results in increased expression of GALP protein
CTD
PMID:32738333
NCBI chr 1:76,717,110...76,741,056
Ensembl chr 1:76,717,110...76,735,354
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Galr2
galanin receptor 2
increases expression
EXP
deoxynivalenol results in increased expression of GALR2 mRNA
CTD
PMID:32738333
NCBI chr10:102,012,086...102,016,057
Ensembl chr10:102,013,370...102,016,055
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Galr3
galanin receptor 3
increases expression
EXP
deoxynivalenol results in increased expression of GALR3 mRNA
CTD
PMID:32738333
NCBI chr 7:112,483,183...112,496,359
Ensembl chr 7:112,485,672...112,488,136
G
Ganab
glucosidase II alpha subunit
decreases expression
ISO
deoxynivalenol results in decreased expression of GANAB protein
CTD
PMID:39638853
NCBI chr 1:215,222,918...215,242,808
Ensembl chr 1:215,222,995...215,243,036
G
Gatad2a
GATA zinc finger domain containing 2A
affects phosphorylation increases expression
ISO
deoxynivalenol affects the phosphorylation of GATAD2A protein deoxynivalenol results in increased expression of GATAD2A protein
CTD
PMID:23352502 PMID:39638853
NCBI chr16:19,463,500...19,553,497
Ensembl chr16:19,463,500...19,553,497
G
Gcg
glucagon
multiple interactions increases expression increases secretion
ISO
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [deoxynivalenol results in increased secretion of GCG protein alternative form]; 2-aminoethyl diphenylborinate inhibits the reaction [deoxynivalenol results in increased secretion of GCG protein alternative form]; Egtazic Acid inhibits the reaction [deoxynivalenol results in increased secretion of GCG protein alternative form]; Nitrendipine inhibits the reaction [deoxynivalenol results in increased secretion of GCG protein alternative form]; triphenylphosphine oxide inhibits the reaction [deoxynivalenol results in increased secretion of GCG protein alternative form] deoxynivalenol results in increased expression of GCG protein
CTD
PMID:25787141 PMID:28633506
NCBI chr 3:67,522,489...67,531,533
Ensembl chr 3:67,522,489...67,531,533
G
Gchfr
GTP cyclohydrolase I feedback regulator
decreases expression
ISO
deoxynivalenol results in decreased expression of GCHFR protein
CTD
PMID:39638853
NCBI chr 3:126,611,892...126,615,926
Ensembl chr 3:126,613,240...126,615,926
G
Gclc
glutamate-cysteine ligase, catalytic subunit
decreases expression multiple interactions
ISO
deoxynivalenol results in decreased expression of GCLC mRNA NNMT protein promotes the reaction [deoxynivalenol results in decreased expression of GCLC protein]; Resveratrol inhibits the reaction [deoxynivalenol results in decreased expression of GCLC protein] deoxynivalenol results in decreased expression of GCLC mRNA; deoxynivalenol results in decreased expression of GCLC protein Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of GCLC mRNA]
CTD
PMID:35817260 PMID:37419272 PMID:39147090 PMID:39983889
NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:87,510,463...87,548,893
G
Gclm
glutamate cysteine ligase, modifier subunit
increases expression
ISO
deoxynivalenol results in increased expression of GCLM mRNA
CTD
PMID:34400200
NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:213,031,838...213,055,003
G
Gdf15
growth differentiation factor 15
increases expression
ISO
deoxynivalenol results in increased expression of GDF15 protein
CTD
PMID:39638853
NCBI chr16:18,838,436...18,842,022
Ensembl chr16:18,838,436...18,842,022
G
Gdf5
growth differentiation factor 5
increases expression
ISO
deoxynivalenol results in increased expression of GDF5 mRNA
CTD
PMID:31863870
NCBI chr 3:164,914,401...164,918,593
Ensembl chr 3:164,914,401...164,918,593
G
Gh1
growth hormone 1
multiple interactions decreases secretion decreases expression
EXP
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in decreased expression of GH1 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in decreased expression of GH1 protein]; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [deoxynivalenol results in decreased expression of GH1 mRNA]; deoxynivalenol results in decreased expression of and results in decreased secretion of GH1 protein; farnesylthiosalicylic acid inhibits the reaction [deoxynivalenol results in decreased expression of GH1 mRNA]; farnesylthiosalicylic acid inhibits the reaction [deoxynivalenol results in decreased expression of GH1 protein]; pyrazolanthrone inhibits the reaction [deoxynivalenol results in decreased expression of GH1 mRNA]; pyrazolanthrone inhibits the reaction [deoxynivalenol results in decreased expression of GH1 protein]; SB 203580 inhibits the reaction [deoxynivalenol results in decreased expression of GH1 mRNA]; SB 203580 inhibits the reaction [deoxynivalenol results in decreased expression of GH1 protein] deoxynivalenol results in decreased secretion of GH1 protein
CTD
PMID:26141394 PMID:32738333 PMID:34673182
NCBI chr10:91,727,883...91,729,860
Ensembl chr10:91,727,884...91,729,859
G
Ghr
growth hormone receptor
affects expression
EXP
deoxynivalenol affects the expression of GHR mRNA
CTD
PMID:34673182
NCBI chr 2:54,269,066...54,532,595
Ensembl chr 2:54,270,206...54,532,331
G
Ghrh
growth hormone releasing hormone
increases expression
EXP
deoxynivalenol results in increased expression of GHRH mRNA
CTD
PMID:34673182
NCBI chr 3:166,412,763...166,432,519
Ensembl chr 3:166,412,764...166,431,880
G
Gip
gastric inhibitory polypeptide
increases expression
ISO
deoxynivalenol results in increased expression of GIP protein
CTD
PMID:28633506
NCBI chr10:81,465,070...81,473,216
Ensembl chr10:81,465,062...81,473,216
G
Gkap1
G kinase anchoring protein 1
increases expression
ISO
deoxynivalenol results in increased expression of GKAP1 mRNA
CTD
PMID:31863870
NCBI chr17:6,389,377...6,429,091
Ensembl chr17:6,389,377...6,438,279
G
Glb1
galactosidase, beta 1
decreases expression
ISO
deoxynivalenol results in decreased expression of GLB1 protein
CTD
PMID:39638853
NCBI chr 8:122,963,718...123,036,326
Ensembl chr 8:122,963,718...123,036,326
G
Gldc
glycine decarboxylase
decreases expression
ISO
deoxynivalenol results in decreased expression of GLDC protein
CTD
PMID:39638853
NCBI chr 1:237,296,753...237,375,620
Ensembl chr 1:237,296,753...237,375,604
G
Gldn
gliomedin
decreases expression
ISO
deoxynivalenol results in decreased expression of GLDN mRNA
CTD
PMID:31863870
NCBI chr 8:63,575,270...63,619,346
Ensembl chr 8:63,575,270...63,619,346
G
Glg1
golgi glycoprotein 1
decreases expression
ISO
deoxynivalenol results in decreased expression of GLG1 protein
CTD
PMID:39638853
NCBI chr19:56,034,248...56,133,538
Ensembl chr19:56,006,459...56,133,528
G
Gls
glutaminase
increases expression
ISO
deoxynivalenol results in increased expression of GLS protein
CTD
PMID:39638853
NCBI chr 9:56,836,584...56,908,861
Ensembl chr 9:56,836,584...56,908,861
G
Glt8d1
glycosyltransferase 8 domain containing 1
decreases expression
ISO
deoxynivalenol results in decreased expression of GLT8D1 protein
CTD
PMID:39638853
NCBI chr16:6,198,152...6,213,671
Ensembl chr16:6,204,740...6,213,668
G
Glyr1
glyoxylate reductase 1 homolog
decreases expression
ISO
deoxynivalenol results in decreased expression of GLYR1 protein
CTD
PMID:39638853
NCBI chr10:11,038,577...11,074,093
Ensembl chr10:11,038,568...11,074,090
G
Gnl2
G protein nucleolar 2
increases expression
ISO
deoxynivalenol results in increased expression of GNL2 protein
CTD
PMID:39638853
NCBI chr 5:142,577,798...142,603,185
Ensembl chr 5:142,577,731...142,603,178
G
Gnl3
G protein nucleolar 3
increases expression
ISO
deoxynivalenol results in increased expression of GNL3 protein
CTD
PMID:39638853
NCBI chr16:6,213,844...6,220,029
Ensembl chr16:6,213,871...6,219,845
G
Got1
glutamic-oxaloacetic transaminase 1
multiple interactions increases activity
ISO
BMAL1 protein inhibits the reaction [deoxynivalenol results in increased activity of GOT1 protein]
CTD
PMID:36602574
NCBI chr 1:252,306,541...252,337,622
Ensembl chr 1:252,284,434...252,329,871
G
Gp1bb
glycoprotein Ib platelet subunit beta
affects phosphorylation
ISO
deoxynivalenol affects the phosphorylation of GP1BB protein
CTD
PMID:23811945
NCBI chr11:95,882,561...95,883,738
G
Gpc3
glypican 3
decreases expression
ISO
deoxynivalenol results in decreased expression of GPC3 protein
CTD
PMID:39638853
NCBI chr X:136,789,770...137,157,598
Ensembl chr X:136,789,770...137,157,639
G
Gpi
glucose-6-phosphate isomerase
decreases expression
ISO
deoxynivalenol results in decreased expression of GPI protein
CTD
PMID:39638853
NCBI chr 1:95,965,389...95,996,932
Ensembl chr 1:95,965,396...95,993,261
G
Gpkow
G patch domain and KOW motifs
increases expression
ISO
deoxynivalenol results in increased expression of GPKOW mRNA
CTD
PMID:31863870
NCBI chr X:17,463,521...17,478,298
Ensembl chr X:17,463,525...17,478,298
G
Gpn1
GPN-loop GTPase 1
increases phosphorylation
ISO
deoxynivalenol results in increased phosphorylation of GPN1 protein
CTD
PMID:23352502
NCBI chr 6:30,667,337...30,685,011
Ensembl chr 6:30,666,868...30,685,011
G
Gprc5c
G protein-coupled receptor, class C, group 5, member C
decreases expression
ISO
deoxynivalenol results in decreased expression of GPRC5C protein
CTD
PMID:39638853
NCBI chr10:100,385,682...100,407,953
Ensembl chr10:100,383,631...100,426,962
G
Gpt
glutamic--pyruvic transaminase
multiple interactions increases expression increases activity
ISO EXP
acetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [deoxynivalenol results in increased activity of GPT protein]; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased activity of GPT protein]; BMAL1 protein inhibits the reaction [deoxynivalenol results in increased activity of GPT protein]; deoxynivalenol promotes the reaction [Aflatoxin B1 results in increased activity of GPT protein] Bentonite inhibits the reaction [deoxynivalenol results in increased expression of GPT protein]; Charcoal inhibits the reaction [deoxynivalenol results in increased expression of GPT protein]
CTD
PMID:25445755 PMID:26115597 PMID:34400200 PMID:35925383 PMID:36602574
NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160
G
Gpx1
glutathione peroxidase 1
increases phosphorylation increases expression
ISO
deoxynivalenol results in increased phosphorylation of GPX1 protein deoxynivalenol results in increased expression of GPX1 mRNA
CTD
PMID:23811945 PMID:34400200
NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581
G
Gpx4
glutathione peroxidase 4
multiple interactions decreases expression
ISO
NNMT protein promotes the reaction [deoxynivalenol results in decreased expression of GPX4 protein]; Resveratrol inhibits the reaction [deoxynivalenol results in decreased expression of GPX4 protein] Selenomethionine inhibits the reaction [deoxynivalenol results in decreased expression of GPX4 protein] deoxynivalenol results in decreased expression of GPX4 mRNA; deoxynivalenol results in decreased expression of GPX4 protein
CTD
PMID:37419272 PMID:38040082 PMID:39147090 PMID:39983889
NCBI chr 7:10,300,833...10,303,629
Ensembl chr 7:10,300,832...10,303,629
G
Grem1
gremlin 1, DAN family BMP antagonist
decreases expression
ISO
deoxynivalenol results in decreased expression of GREM1 mRNA
CTD
PMID:31863870
NCBI chr 3:120,966,639...120,978,319
Ensembl chr 3:120,966,623...120,979,089
G
Grn
granulin precursor
decreases expression
ISO
deoxynivalenol results in decreased expression of GRN protein
CTD
PMID:39638853
NCBI chr10:87,887,834...87,893,938
Ensembl chr10:87,886,122...87,893,936
G
Grwd1
glutamate-rich WD repeat containing 1
increases expression
ISO
deoxynivalenol results in increased expression of GRWD1 protein
CTD
PMID:39638853
NCBI chr 1:105,437,708...105,443,410
Ensembl chr 1:105,437,709...105,443,825
G
Gsdmd
gasdermin D
increases expression multiple interactions
ISO
deoxynivalenol results in increased expression of GSDMD mRNA; deoxynivalenol results in increased expression of GSDMD protein deoxynivalenol promotes the reaction [fumonisin B1 results in increased expression of GSDMD mRNA]; deoxynivalenol promotes the reaction [fumonisin B1 results in increased expression of GSDMD protein]; deoxynivalenol results in increased expression of and results in increased cleavage of GSDMD protein; fumonisin B1 promotes the reaction [deoxynivalenol results in increased expression of GSDMD mRNA]; fumonisin B1 promotes the reaction [deoxynivalenol results in increased expression of GSDMD protein]
CTD
PMID:35925383 PMID:36309173
NCBI chr 7:109,423,209...109,427,771
Ensembl chr 7:109,422,910...109,430,722
G
Gsdme
gasdermin E
multiple interactions
ISO
acetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [deoxynivalenol results in increased expression of and results in increased cleavage of GSDME protein]; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased expression of and results in increased cleavage of GSDME protein]; deoxynivalenol results in increased expression of and results in increased cleavage of GSDME protein [GSDME protein co-treated with deoxynivalenol] results in increased secretion of IL1B protein; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased cleavage of GSDME protein]; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased cleavage of GSDME protein]; deoxynivalenol results in decreased expression of and results in increased cleavage of GSDME protein; GSDME protein inhibits the reaction [deoxynivalenol results in increased cleavage of PARP1 protein]; GSDME protein promotes the reaction [deoxynivalenol results in increased secretion of IL6 protein]
CTD
PMID:35925383
NCBI chr 4:80,590,344...80,651,943
Ensembl chr 4:80,588,614...80,641,525
G
Gsk3b
glycogen synthase kinase 3 beta
increases phosphorylation
ISO
deoxynivalenol results in increased phosphorylation of GSK3B protein
CTD
PMID:15976193
NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249
G
Gss
glutathione synthetase
increases expression multiple interactions
ISO
deoxynivalenol results in increased expression of GSS mRNA; deoxynivalenol results in increased expression of GSS protein Resveratrol inhibits the reaction [deoxynivalenol results in decreased expression of GSS protein]; Resveratrol promotes the reaction [deoxynivalenol results in increased expression of GSS protein]
CTD
PMID:37419272 PMID:39983889
NCBI chr 3:164,508,005...164,538,343
Ensembl chr 3:164,508,005...164,538,306
G
Gtpbp10
GTP binding protein 10
increases expression
ISO
deoxynivalenol results in increased expression of GTPBP10 protein
CTD
PMID:39638853
NCBI chr 4:29,431,683...29,449,201
Ensembl chr 4:29,431,692...29,449,212
G
Gtpbp4
GTP binding protein 4
increases expression
ISO
deoxynivalenol results in increased expression of GTPBP4 protein
CTD
PMID:39638853
NCBI chr17:65,997,472...66,019,530
Ensembl chr17:66,276,566...66,289,637
G
Guf1
GTP binding elongation factor GUF1
increases expression
ISO
deoxynivalenol results in increased expression of GUF1 protein
CTD
PMID:39638853
NCBI chr14:38,891,905...38,911,283
Ensembl chr14:38,891,905...38,911,283
G
H1f0
H1.0 linker histone
increases expression
ISO
deoxynivalenol results in increased expression of H1-0 mRNA; deoxynivalenol results in increased expression of H1-0 protein
CTD
PMID:31863870 PMID:39638853
NCBI chr 7:112,473,280...112,475,140
Ensembl chr 7:112,473,222...112,475,006
G
H1f10
H1.10 linker histone
increases expression
ISO
deoxynivalenol results in increased expression of H1-10 mRNA; deoxynivalenol results in increased expression of H1-10 protein
CTD
PMID:31863870 PMID:39638853
NCBI chr 4:121,997,834...121,998,897
Ensembl chr 4:121,997,831...121,998,966
G
H1f2
H1.2 linker histone, cluster member
increases expression
ISO
deoxynivalenol results in increased expression of H1-2 mRNA
CTD
PMID:31863870
NCBI chr17:41,818,962...41,820,453
Ensembl chr17:41,779,051...41,822,317
G
H1f4
H1.4 linker histone, cluster member
increases expression
ISO
deoxynivalenol results in increased expression of H1-4 protein
CTD
PMID:39638853
NCBI chr17:41,914,425...41,915,206
Ensembl chr17:41,914,431...41,916,129
G
H1f5
H1.5 linker histone, cluster member
decreases phosphorylation
ISO
deoxynivalenol results in decreased phosphorylation of H1F5 protein
CTD
PMID:23352502
NCBI chr17:47,421,875...47,422,905
Ensembl chr17:47,421,843...47,477,387
G
H3-7l
H3.7 histone like
increases expression
ISO
deoxynivalenol results in increased expression of H3-7 protein
CTD
PMID:39638853
NCBI chr 7:102,145,916...102,146,683
G
Hapln1
hyaluronan and proteoglycan link protein 1
decreases expression
ISO
deoxynivalenol results in decreased expression of HAPLN1 mRNA
CTD
PMID:31863870
NCBI chr 2:22,366,967...22,431,709
Ensembl chr 2:22,366,967...22,429,098
G
Haus2
HAUS augmin like complex subunit 2
increases expression
ISO
deoxynivalenol results in increased expression of HAUS2 mRNA
CTD
PMID:31863870
NCBI chr 3:128,006,894...128,019,730
Ensembl chr 3:128,006,932...128,019,729
G
Hba-a1
hemoglobin alpha, adult chain 1
increases phosphorylation
ISO
deoxynivalenol results in increased phosphorylation of HBA protein
CTD
PMID:23811945
NCBI chr10:15,841,724...15,842,580
Ensembl chr10:15,841,763...15,842,603
G
Hbb
hemoglobin subunit beta
affects phosphorylation
ISO
deoxynivalenol affects the phosphorylation of HBB-B1 protein
CTD
PMID:23811945
NCBI chr 1:167,662,310...167,663,721
Ensembl chr 1:167,630,245...167,663,873
G
Hck
HCK proto-oncogene, Src family tyrosine kinase
increases phosphorylation affects response to substance multiple interactions
ISO
deoxynivalenol results in increased phosphorylation of HCK protein HCK protein affects the susceptibility to deoxynivalenol 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased phosphorylation of and results in increased activity of HCK protein]; deoxynivalenol results in increased phosphorylation of and results in increased activity of HCK protein; HCK protein affects the reaction [deoxynivalenol results in increased activity of CASP3 protein]; HCK protein affects the reaction [deoxynivalenol results in increased expression of TNF protein]
CTD
PMID:15772366 PMID:20181660 PMID:22491426
NCBI chr 3:162,031,833...162,074,933
Ensembl chr 3:162,031,817...162,074,935
G
Hdac1
histone deacetylase 1
affects phosphorylation
ISO
deoxynivalenol affects the phosphorylation of HDAC1 protein
CTD
PMID:23352502
NCBI chr 5:147,138,328...147,165,387
Ensembl chr 5:147,138,156...147,165,387
G
Hdac2
histone deacetylase 2
affects phosphorylation increases expression
ISO
deoxynivalenol affects the phosphorylation of HDAC2 protein deoxynivalenol results in increased expression of HDAC2 protein
CTD
PMID:23352502 PMID:39638853
NCBI chr20:42,101,815...42,126,486
Ensembl chr20:42,102,861...42,126,311
G
Hdgf
heparin binding growth factor
decreases phosphorylation
ISO
deoxynivalenol results in decreased phosphorylation of HDGF protein
CTD
PMID:23811945
NCBI chr 2:175,668,290...175,677,614
Ensembl chr 2:175,668,324...175,677,225
G
Heatr1
HEAT repeat containing 1
increases expression
ISO
deoxynivalenol results in increased expression of HEATR1 protein
CTD
PMID:39638853
NCBI chr17:62,745,008...62,785,609
Ensembl chr17:62,745,008...62,785,186
G
Hells
helicase, lymphoid specific
increases expression
ISO
deoxynivalenol results in increased expression of HELLS protein
CTD
PMID:39638853
NCBI chr 1:246,113,580...246,159,230
Ensembl chr 1:246,114,096...246,159,228
G
Hemgn
hemogen
affects phosphorylation
ISO
deoxynivalenol affects the phosphorylation of HEMGN protein
CTD
PMID:23811945
NCBI chr 5:65,475,228...65,495,384
Ensembl chr 5:65,475,228...65,494,375
G
Hif1a
hypoxia inducible factor 1 subunit alpha
increases expression multiple interactions
ISO
deoxynivalenol results in increased expression of HIF1A mRNA Selenomethionine inhibits the reaction [deoxynivalenol results in increased expression of HIF1A protein] 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in increased expression of HIF1A mRNA]
CTD
PMID:34677630 PMID:38040082
NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323
G
Hinfp
histone H4 transcription factor
increases expression
ISO
deoxynivalenol results in increased expression of HINFP protein
CTD
PMID:33890134
NCBI chr 8:53,525,576...53,541,101
Ensembl chr 8:53,527,236...53,540,555
G
Hint1
histidine triad nucleotide binding protein 1
decreases expression
ISO
deoxynivalenol results in decreased expression of HINT1 mRNA
CTD
PMID:15371230
NCBI chr10:39,490,225...39,493,970
Ensembl chr 4:93,430,926...93,431,642 Ensembl chr10:93,430,926...93,431,642
G
Hist1h2bd
histone cluster 1 H2B family member D
increases expression
ISO
deoxynivalenol results in increased expression of H2BC5 mRNA
CTD
PMID:31863870
NCBI chr17:47,488,627...47,489,008
G
Hlx
H2.0-like homeobox
increases expression
ISO
deoxynivalenol results in increased expression of HLX mRNA
CTD
PMID:31863870
NCBI chr13:98,811,852...98,817,264
Ensembl chr13:98,811,856...98,817,264
G
Hmgcr
3-hydroxy-3-methylglutaryl-CoA reductase
decreases expression
ISO
deoxynivalenol results in decreased expression of HMGCR mRNA
CTD
PMID:22982764
NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:29,720,553...29,754,533
G
Hmox1
heme oxygenase 1
decreases expression multiple interactions increases expression decreases response to substance
ISO
deoxynivalenol results in decreased expression of HMOX1 mRNA; deoxynivalenol results in decreased expression of HMOX1 protein 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in increased expression of HMOX1 mRNA] deoxynivalenol results in increased expression of HMOX1 mRNA; deoxynivalenol results in increased expression of HMOX1 protein Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of HMOX1 mRNA]; HMOX1 protein inhibits the reaction [deoxynivalenol results in increased expression of IL1B protein]; HMOX1 protein inhibits the reaction [deoxynivalenol results in increased expression of IL6 protein]; HMOX1 protein inhibits the reaction [deoxynivalenol results in increased expression of TNF protein]; Selenomethionine inhibits the reaction [deoxynivalenol results in increased expression of HMOX1 protein] HMOX1 protein results in decreased susceptibility to deoxynivalenol
CTD
PMID:24355168 PMID:26763390 PMID:31034930 PMID:31863870 PMID:34400200 PMID:34677630 PMID:35314294 PMID:35817260 PMID:38040082 PMID:39638853 PMID:39983889 More...
NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
G
Hmox2
heme oxygenase 2
increases expression
ISO
deoxynivalenol results in increased expression of HMOX2 protein
CTD
PMID:39638853
NCBI chr10:11,303,512...11,337,640
Ensembl chr10:11,303,512...11,318,800
G
Hnf4a
hepatocyte nuclear factor 4, alpha
increases expression multiple interactions
ISO
deoxynivalenol results in increased expression of HNF4 mRNA; deoxynivalenol results in increased expression of HNF4A mRNA [deoxynivalenol co-treated with Zearalenone] affects the expression of HNF4A mRNA
CTD
PMID:28865950 PMID:35314294
NCBI chr 3:172,606,220...172,667,758
Ensembl chr 3:172,606,220...172,667,758
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Hnrnpf
heterogeneous nuclear ribonucleoprotein F
increases expression
ISO
deoxynivalenol results in increased expression of HNRNPF protein
CTD
PMID:39638853
NCBI chr 4:152,755,668...152,776,867
Ensembl chr 4:152,722,617...152,815,769
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Hnrnph1
heterogeneous nuclear ribonucleoprotein H1
increases expression
ISO
deoxynivalenol results in increased expression of HNRNPH1 protein
CTD
PMID:39638853
NCBI chr10:35,187,412...35,203,909
Ensembl chr10:35,193,890...35,203,906
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Hnrnpul1
heterogeneous nuclear ribonucleoprotein U-like 1
increases expression
ISO
deoxynivalenol results in increased expression of HNRNPUL1 protein
CTD
PMID:39638853
NCBI chr 1:90,356,182...90,391,923
Ensembl chr 1:90,356,182...90,390,370
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Hoxa7
homeobox A7
increases expression multiple interactions
ISO
deoxynivalenol results in increased expression of HOXA7 mRNA AG 1879 inhibits the reaction [deoxynivalenol results in increased expression of HOXA7 mRNA]
CTD
PMID:19438726
NCBI chr 4:82,646,342...82,652,449
Ensembl chr 4:82,646,364...82,648,241
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Hsd3b2
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
increases expression
ISO
deoxynivalenol results in increased expression of HSD3B2 mRNA
CTD
PMID:22982764
NCBI chr 2:188,784,614...188,812,535
Ensembl chr 2:188,784,614...188,790,569
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Hsp90ab1
heat shock protein 90 alpha family class B member 1
affects phosphorylation
ISO
deoxynivalenol affects the phosphorylation of HSP90AB1 protein
CTD
PMID:23811945
NCBI chr 9:22,930,249...22,935,929
Ensembl chr 9:22,931,070...22,935,926
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Hspa1l
heat shock protein family A (Hsp70) member 1 like
decreases expression
ISO
deoxynivalenol results in decreased expression of HSPA1L protein
CTD
PMID:33890134
NCBI chr20:3,853,496...3,860,223
Ensembl chr20:3,853,331...3,876,877
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Hspa5
heat shock protein family A (Hsp70) member 5
multiple interactions increases phosphorylation decreases expression
ISO
calpain inhibitor III inhibits the reaction [deoxynivalenol results in increased degradation of HSPA5 protein]; deoxynivalenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HSPA5 mRNA]; deoxynivalenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HSPA5 protein]; deoxynivalenol results in increased degradation of and results in decreased expression of HSPA5 protein; phenylalanyl-glycyl-NHO-Bz inhibits the reaction [deoxynivalenol results in increased degradation of HSPA5 protein] deoxynivalenol results in increased phosphorylation of HSPA5 protein deoxynivalenol results in decreased expression of HSPA5 mRNA
CTD
PMID:10652249 PMID:19336499 PMID:20682335 PMID:23811945 PMID:24356939
NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790
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Hspa8
heat shock protein family A (Hsp70) member 8
increases phosphorylation
ISO
deoxynivalenol results in increased phosphorylation of HSPA8 protein
CTD
PMID:23811945
NCBI chr 8:50,080,514...50,084,376
Ensembl chr 8:50,080,199...50,084,372
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Hspg2
heparan sulfate proteoglycan 2
decreases expression
ISO
deoxynivalenol results in decreased expression of HSPG2 protein
CTD
PMID:39638853
NCBI chr 5:154,960,818...155,061,971
Ensembl chr 5:154,960,846...155,061,971
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Hsph1
heat shock protein family H (Hsp110) member 1
increases phosphorylation
ISO
deoxynivalenol results in increased phosphorylation of HSPH1 protein
CTD
PMID:23352502
NCBI chr12:10,427,368...10,446,602
Ensembl chr12:10,427,297...10,446,891
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Hyls1
HYLS1, centriolar and ciliogenesis associated
increases expression
ISO
deoxynivalenol results in increased expression of HYLS1 mRNA
CTD
PMID:31863870
NCBI chr 8:42,170,505...42,179,573
Ensembl chr 8:42,168,546...42,179,725
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Icam1
intercellular adhesion molecule 1
increases expression multiple interactions
ISO
deoxynivalenol results in increased expression of ICAM1 mRNA; deoxynivalenol results in increased expression of ICAM1 protein deoxynivalenol inhibits the reaction [IFNG protein results in increased expression of ICAM1 protein]
CTD
PMID:19549553 PMID:21074547 PMID:34400200 PMID:39638853
NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617
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Id1
inhibitor of DNA binding 1
decreases expression
ISO
deoxynivalenol results in decreased expression of ID1 mRNA
CTD
PMID:31863870
NCBI chr 3:161,671,525...161,672,691
Ensembl chr 3:161,671,538...161,672,685
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Idh1
isocitrate dehydrogenase (NADP(+)) 1
decreases expression
ISO
deoxynivalenol results in decreased expression of IDH1 protein
CTD
PMID:39638853
NCBI chr 9:74,027,887...74,057,442
Ensembl chr 9:74,027,892...74,049,555
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Ifitm3
interferon induced transmembrane protein 3
decreases expression
ISO
deoxynivalenol results in decreased expression of IFITM3 protein
CTD
PMID:33890134
NCBI chr 1:205,540,649...205,541,758
Ensembl chr 1:205,481,168...205,547,920
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Ifna1
interferon, alpha 1
decreases expression
ISO
deoxynivalenol results in decreased expression of IFNA1 mRNA
CTD
PMID:17090620
NCBI chr 5:108,143,240...108,143,809
Ensembl chr 5:108,143,240...108,143,809
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Ifnar1
interferon alpha and beta receptor subunit 1
decreases expression
ISO
deoxynivalenol results in decreased expression of IFNAR1 mRNA
CTD
PMID:17090620
NCBI chr11:44,211,769...44,238,206
Ensembl chr11:44,211,845...44,238,205
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Ifnb1
interferon beta 1
multiple interactions increases expression
ISO
deoxynivalenol inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IFNB1 mRNA]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA] deoxynivalenol results in increased expression of IFNB1 mRNA
CTD
PMID:14644621 PMID:17090620 PMID:19857559
NCBI chr 5:108,066,650...108,067,487
Ensembl chr 5:108,066,650...108,067,487
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Ifng
interferon gamma
affects expression multiple interactions increases expression
ISO
deoxynivalenol affects the expression of IFNG mRNA 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; Adenine inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased abundance of Nitric Oxide]; deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]; deoxynivalenol inhibits the reaction [IFNG protein results in increased expression of CD14 protein]; deoxynivalenol inhibits the reaction [IFNG protein results in increased expression of ICAM1 protein]; deoxynivalenol inhibits the reaction [IFNG protein results in increased expression of IFNGR1 protein]; lactacystin inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; SB 203580 inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]] deoxynivalenol results in increased expression of IFNG mRNA; deoxynivalenol results in increased expression of IFNG protein [deoxynivalenol co-treated with Aflatoxin B1] results in decreased expression of IFNG mRNA; [deoxynivalenol results in increased susceptibility to Antigens] which results in increased expression of IFNG protein; Celecoxib inhibits the reaction [deoxynivalenol results in increased expression of IFNG protein]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of IFNG mRNA]
CTD
PMID:9194413 PMID:9707511 PMID:14644621 PMID:17090620 PMID:17166736 PMID:19549553 PMID:20702593 PMID:22968694 PMID:24937323 PMID:25766886 PMID:28935500 PMID:32416088 PMID:38763499 More...
NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216
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Ifngr1
interferon gamma receptor 1
multiple interactions decreases expression
ISO
deoxynivalenol inhibits the reaction [IFNG protein results in increased expression of IFNGR1 protein] deoxynivalenol results in decreased expression of IFNGR1 mRNA
CTD
PMID:17090620 PMID:19549553
NCBI chr 1:16,152,811...16,171,439
Ensembl chr 1:16,152,879...16,171,437
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Igf1
insulin-like growth factor 1
multiple interactions increases expression decreases expression
ISO EXP
deoxynivalenol promotes the reaction [Glutathione results in increased expression of IGF1 mRNA] deoxynivalenol results in increased expression of IGF1 mRNA deoxynivalenol results in decreased expression of IGF1 protein
CTD
PMID:19805407 PMID:32738333
NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764
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Igf2
insulin-like growth factor 2
decreases expression
ISO
deoxynivalenol results in decreased expression of IGF2 protein
CTD
PMID:39638853
NCBI chr 1:207,243,873...207,261,263
Ensembl chr 1:207,243,873...207,260,667
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Igfals
insulin-like growth factor binding protein, acid labile subunit
decreases expression increases expression multiple interactions
ISO EXP
deoxynivalenol results in decreased expression of IGFALS mRNA; deoxynivalenol results in decreased expression of IGFALS protein deoxynivalenol results in increased expression of IGFALS mRNA deoxynivalenol inhibits the reaction [Glutathione results in increased expression of IGFALS mRNA]
CTD
PMID:19625342 PMID:19805407 PMID:23298694 PMID:32738333
NCBI chr10:14,397,076...14,408,439
Ensembl chr10:14,403,399...14,407,138
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Igfbp3
insulin-like growth factor binding protein 3
multiple interactions
ISO
deoxynivalenol promotes the reaction [Glutathione results in increased expression of IGFBP3 mRNA]
CTD
PMID:19805407
NCBI chr14:86,270,208...86,277,944
Ensembl chr14:86,270,208...86,277,944
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Igfbp6
insulin-like growth factor binding protein 6
decreases expression
ISO
deoxynivalenol results in decreased expression of IGFBP6 mRNA
CTD
PMID:31863870
NCBI chr 7:135,154,919...135,159,550
Ensembl chr 7:135,154,685...135,159,795
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Igsf1
immunoglobulin superfamily, member 1
decreases expression
ISO
deoxynivalenol results in decreased expression of IGSF1 protein
CTD
PMID:39638853
NCBI chr X:133,947,717...133,963,154
Ensembl chr X:133,947,429...133,962,962
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Il10
interleukin 10
increases expression multiple interactions
ISO
deoxynivalenol results in increased expression of IL10 mRNA alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [deoxynivalenol promotes the reaction [IL10 protein results in increased expression of IL1B mRNA]]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [deoxynivalenol promotes the reaction [IL10 protein results in increased expression of TNF mRNA]]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [deoxynivalenol promotes the reaction [IL10 protein results in increased phosphorylation of JAK2 mRNA]]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [deoxynivalenol promotes the reaction [IL10 protein results in increased phosphorylation of JAK2 protein]]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [deoxynivalenol promotes the reaction [IL10 protein results in increased phosphorylation of STAT3 mRNA]]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [deoxynivalenol promotes the reaction [IL10 protein results in increased phosphorylation of STAT3 protein]]; deoxynivalenol promotes the reaction [IL10 protein results in increased expression of IL1B mRNA]; deoxynivalenol promotes the reaction [IL10 protein results in increased expression of SOCS3 mRNA]; deoxynivalenol promotes the reaction [IL10 protein results in increased expression of SOCS3 protein]; deoxynivalenol promotes the reaction [IL10 protein results in increased expression of TNF mRNA]; deoxynivalenol promotes the reaction [IL10 protein results in increased phosphorylation of JAK2 mRNA]; deoxynivalenol promotes the reaction [IL10 protein results in increased phosphorylation of JAK2 protein]; deoxynivalenol promotes the reaction [IL10 protein results in increased phosphorylation of STAT3 mRNA]; deoxynivalenol promotes the reaction [IL10 protein results in increased phosphorylation of STAT3 protein]
CTD
PMID:9194413 PMID:9707511 PMID:22968694 PMID:38432439
NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580
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Il10rb
interleukin 10 receptor subunit beta
increases expression
ISO
deoxynivalenol results in increased expression of IL10RB mRNA
CTD
PMID:22968694
NCBI chr11:44,132,471...44,154,062
Ensembl chr11:44,132,189...44,154,053
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Il11
interleukin 11
increases expression affects expression multiple interactions
ISO EXP
deoxynivalenol results in increased expression of IL11 mRNA deoxynivalenol affects the expression of IL11 mRNA deoxynivalenol results in increased expression of IL11 mRNA; deoxynivalenol results in increased expression of IL11 protein GALP protein promotes the reaction [deoxynivalenol results in increased expression of IL11 protein] Fatty Acids, Omega-3 inhibits the reaction [deoxynivalenol results in increased expression of IL11 mRNA]
CTD
PMID:15371230 PMID:15681167 PMID:32738333 PMID:34673182
NCBI chr 1:78,098,622...78,104,915
Ensembl chr 1:78,096,930...78,104,915
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Il12a
interleukin 12A
increases expression
ISO
deoxynivalenol results in increased expression of IL12A mRNA
CTD
PMID:9707511 PMID:27757495
NCBI chr 2:155,275,734...155,282,997
Ensembl chr 2:155,275,625...155,282,997
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Il12b
interleukin 12B
increases expression multiple interactions
ISO
deoxynivalenol results in increased expression of IL12B mRNA [Lipopolysaccharides co-treated with deoxynivalenol] results in increased expression of IL12B protein
CTD
PMID:9194413 PMID:9707511 PMID:28935500
NCBI chr10:29,390,300...29,405,194
Ensembl chr10:29,389,905...29,405,194
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Il13
interleukin 13
multiple interactions
ISO
deoxynivalenol promotes the reaction [Antigens, Dermatophagoides results in increased expression of and results in increased secretion of IL13 protein]
CTD
PMID:33170220
NCBI chr10:38,290,926...38,293,483
Ensembl chr10:38,290,926...38,293,483
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Il15
interleukin 15
increases expression
ISO
deoxynivalenol results in increased expression of IL15 mRNA
CTD
PMID:27757495
NCBI chr19:42,536,160...42,611,349
Ensembl chr19:42,545,346...42,611,348
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Il17a
interleukin 17A
multiple interactions increases expression
ISO
[deoxynivalenol results in increased susceptibility to Antigens] which results in increased expression of IL17A protein; Celecoxib inhibits the reaction [deoxynivalenol results in increased expression of IL17A protein]
CTD
PMID:28935500 PMID:32416088
NCBI chr 9:30,640,844...30,644,331
Ensembl chr 9:30,640,844...30,644,331
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Il18
interleukin 18
decreases expression increases secretion increases expression multiple interactions
ISO
deoxynivalenol results in decreased expression of IL18 mRNA deoxynivalenol results in increased secretion of IL18 protein deoxynivalenol results in increased expression of IL18 mRNA; deoxynivalenol results in increased expression of IL18 protein acetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [deoxynivalenol results in increased expression of IL18 mRNA]; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased expression of IL18 mRNA]; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased secretion of IL18 protein]; deoxynivalenol promotes the reaction [fumonisin B1 results in increased expression of IL18 mRNA]; deoxynivalenol promotes the reaction [fumonisin B1 results in increased expression of IL18 protein]; deoxynivalenol promotes the reaction [fumonisin B1 results in increased secretion of IL18 protein]; fumonisin B1 promotes the reaction [deoxynivalenol results in increased expression of IL18 mRNA]; fumonisin B1 promotes the reaction [deoxynivalenol results in increased expression of IL18 protein]; fumonisin B1 promotes the reaction [deoxynivalenol results in increased secretion of IL18 protein]
CTD
PMID:22968694 PMID:35925383 PMID:36309173
NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:59,809,592...59,831,286
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Il18rap
interleukin 18 receptor accessory protein
decreases expression
ISO
deoxynivalenol results in decreased expression of IL18RAP mRNA
CTD
PMID:22968694
NCBI chr 9:50,263,723...50,296,583
Ensembl chr 9:50,263,733...50,296,583
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Il1a
interleukin 1 alpha
increases expression multiple interactions
ISO EXP
deoxynivalenol results in increased expression of IL1A mRNA Fatty Acids, Omega-3 inhibits the reaction [deoxynivalenol results in increased expression of IL1A mRNA]; Lipopolysaccharides promotes the reaction [deoxynivalenol results in increased expression of IL1A mRNA]
CTD
PMID:15371230 PMID:15681167 PMID:16009389 PMID:32738333
NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013
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Il1b
interleukin 1 beta
increases expression increases secretion multiple interactions decreases expression
ISO EXP
deoxynivalenol results in increased expression of IL1B mRNA; deoxynivalenol results in increased expression of IL1B protein deoxynivalenol results in increased secretion of IL1B protein GALP protein promotes the reaction [deoxynivalenol results in increased expression of IL1B protein] 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; [GSDME protein co-treated with deoxynivalenol] results in increased secretion of IL1B protein; [Zearalenone co-treated with deoxynivalenol] results in increased expression of IL1B mRNA; Adenine inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased secretion of IL1B protein]; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased secretion of IL1B protein]; deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased abundance of Nitric Oxide]; deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]; deoxynivalenol inhibits the reaction [IL1B protein results in increased expression of CXCL8 protein]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; lactacystin inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; SB 203580 inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]] 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide promotes the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of IL1B mRNA]]; 6-formylindolo(3,2-b)carbazole inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of IL1B mRNA]]; [deoxynivalenol results in increased susceptibility to Antigens] which results in increased expression of IL1B protein; [Lipopolysaccharides co-treated with deoxynivalenol] results in increased expression of IL1B mRNA; [Lipopolysaccharides co-treated with deoxynivalenol] results in increased expression of IL1B protein; acetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [deoxynivalenol results in increased expression of IL1B mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [deoxynivalenol promotes the reaction [IL10 protein results in increased expression of IL1B mRNA]]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [deoxynivalenol results in increased expression of IL1B mRNA]; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased expression of IL1B mRNA]; BMAL1 protein inhibits the reaction [deoxynivalenol results in increased expression of IL1B protein]; Curcumin inhibits the reaction [deoxynivalenol results in increased expression of IL1B mRNA]; deoxynivalenol promotes the reaction [Antigens, Dermatophagoides results in increased expression of IL1B protein]; deoxynivalenol promotes the reaction [fumonisin B1 results in increased expression of IL1B mRNA]; deoxynivalenol promotes the reaction [fumonisin B1 results in increased expression of IL1B protein]; deoxynivalenol promotes the reaction [fumonisin B1 results in increased secretion of IL1B protein]; deoxynivalenol promotes the reaction [IL10 protein results in increased expression of IL1B mRNA]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of IL1B protein]; fumonisin B1 promotes the reaction [deoxynivalenol results in increased expression of IL1B mRNA]; fumonisin B1 promotes the reaction [deoxynivalenol results in increased expression of IL1B protein]; fumonisin B1 promotes the reaction [deoxynivalenol results in increased secretion of IL1B protein]; HMOX1 protein inhibits the reaction [deoxynivalenol results in increased expression of IL1B protein]; Lipopolysaccharides promotes the reaction [deoxynivalenol results in increased expression of IL1B mRNA]; Lipopolysaccharides promotes the reaction [deoxynivalenol results in increased expression of IL1B protein]; Poly I-C promotes the reaction [deoxynivalenol results in increased expression of IL1B mRNA]; resiquimod promotes the reaction [deoxynivalenol results in increased expression of IL1B mRNA]; sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of IL1B mRNA]; stattic inhibits the reaction [deoxynivalenol results in increased expression of IL1B mRNA]; Zymosan promotes the reaction [deoxynivalenol results in increased expression of IL1B mRNA] deoxynivalenol results in decreased expression of IL1B mRNA
CTD
PMID:9194413 PMID:9707511 PMID:10344227 PMID:12604842 PMID:12773775 PMID:15371230 PMID:15681167 PMID:16009389 PMID:16364386 PMID:16687389 PMID:18308354 PMID:18433975 PMID:18614267 PMID:20702593 PMID:21873375 PMID:22454431 PMID:22968694 PMID:24793808 PMID:25392278 PMID:25549547 PMID:25766886 PMID:28935500 PMID:31034930 PMID:32738333 PMID:33170220 PMID:33890134 PMID:34400200 PMID:34673182 PMID:35090964 PMID:35381244 PMID:35817260 PMID:35925383 PMID:36309173 PMID:36602574 PMID:38432439 More...
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
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Il1f10
interleukin 1 family member 10
increases expression
ISO
deoxynivalenol results in increased expression of IL1F10 mRNA
CTD
PMID:22968694
NCBI chr 3:27,470,798...27,473,726
Ensembl chr 3:27,470,798...27,473,726
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Il1r1
interleukin 1 receptor type 1
increases expression multiple interactions
ISO
deoxynivalenol results in increased expression of IL1R1 mRNA IL1R1 protein affects the susceptibility to [Lipopolysaccharides co-treated with deoxynivalenol]
CTD
PMID:12773775 PMID:22968694
NCBI chr 9:50,000,558...50,076,579
Ensembl chr 9:50,000,566...50,076,579
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Il1rl1
interleukin 1 receptor-like 1
increases expression
ISO
deoxynivalenol results in increased expression of IL1RL1 mRNA
CTD
PMID:26304032
NCBI chr 9:50,157,326...50,222,888
Ensembl chr 9:50,204,551...50,222,891
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Il1rn
interleukin 1 receptor antagonist
increases expression
ISO
deoxynivalenol results in increased expression of IL1RN mRNA
CTD
PMID:22968694
NCBI chr 3:27,509,836...27,525,738
Ensembl chr 3:27,509,798...27,525,732
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Il2
interleukin 2
affects secretion increases expression increases stability multiple interactions affects expression
ISO
deoxynivalenol affects the secretion of IL2 protein deoxynivalenol results in increased expression of IL2 mRNA deoxynivalenol results in increased stability of IL2 mRNA [deoxynivalenol co-treated with Aflatoxin B1] results in decreased expression of IL2 mRNA; deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein] deoxynivalenol affects the expression of IL2 mRNA
CTD
PMID:8560498 PMID:8658534 PMID:9194413 PMID:9439728 PMID:9707511 PMID:17166736 PMID:38763499 More...
NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672
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Il22ra2
interleukin 22 receptor subunit alpha 2
increases expression
ISO
deoxynivalenol results in increased expression of IL22RA2 mRNA
CTD
PMID:22968694
NCBI chr 1:16,172,238...16,228,009
Ensembl chr 1:16,184,113...16,197,950
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Il23a
interleukin 23 subunit alpha
increases expression
ISO
deoxynivalenol results in increased expression of IL23A mRNA
CTD
PMID:22968694
NCBI chr 7:1,306,320...1,308,434
Ensembl chr 7:1,306,320...1,308,434
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Il33
interleukin 33
increases expression multiple interactions
ISO
deoxynivalenol results in increased expression of IL33 mRNA; deoxynivalenol results in increased expression of IL33 protein deoxynivalenol promotes the reaction [Antigens, Dermatophagoides results in increased expression of IL33 protein]; Oligosaccharides analog inhibits the reaction [deoxynivalenol results in increased expression of IL33 mRNA]; Oligosaccharides analog inhibits the reaction [deoxynivalenol results in increased expression of IL33 protein]
CTD
PMID:26304032 PMID:33170220
NCBI chr 1:237,115,478...237,149,897
Ensembl chr 1:237,115,572...237,150,901
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Il36g
interleukin 36, gamma
increases expression
ISO
deoxynivalenol results in increased expression of IL36G protein
CTD
PMID:33890134
NCBI chr 3:27,346,675...27,352,839
Ensembl chr 3:27,346,670...27,352,834
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Il4
interleukin 4
increases expression multiple interactions affects secretion
ISO
deoxynivalenol results in increased expression of IL4 mRNA deoxynivalenol results in increased expression of IL4 mRNA; deoxynivalenol results in increased expression of IL4 protein deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 mRNA]; deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 protein]; deoxynivalenol promotes the reaction [Antigens, Dermatophagoides results in increased expression of and results in increased secretion of IL4 protein] deoxynivalenol affects the secretion of IL4 protein
CTD
PMID:8560498 PMID:8658534 PMID:9194413 PMID:9707511 PMID:22846391 PMID:24937323 PMID:33170220 More...
NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549
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Il5
interleukin 5
affects secretion increases expression multiple interactions
ISO
deoxynivalenol affects the secretion of IL5 protein deoxynivalenol results in increased expression of IL5 mRNA deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 mRNA]; deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 protein]; deoxynivalenol promotes the reaction [Antigens, Dermatophagoides results in increased expression of and results in increased secretion of IL5 protein]
CTD
PMID:8560498 PMID:8658534 PMID:33170220
NCBI chr10:38,375,132...38,378,003
Ensembl chr10:38,375,132...38,378,003
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Il6
interleukin 6
decreases expression increases secretion multiple interactions increases expression increases stability
ISO EXP
deoxynivalenol results in decreased expression of IL6 mRNA deoxynivalenol results in increased secretion of IL6 protein [Zearalenone co-treated with deoxynivalenol] results in increased expression of IL6 mRNA; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased secretion of IL6 protein]; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased secretion of IL6 protein]; GSDME protein promotes the reaction [deoxynivalenol results in increased secretion of IL6 protein] deoxynivalenol results in increased expression of IL6 mRNA; deoxynivalenol results in increased expression of IL6 protein GALP protein promotes the reaction [deoxynivalenol results in increased expression of IL6 protein] 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide promotes the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of IL6 mRNA]]; 6-formylindolo(3,2-b)carbazole inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of IL6 mRNA]]; [deoxynivalenol co-treated with Aflatoxin B1] results in decreased expression of IL6 mRNA; [deoxynivalenol results in increased susceptibility to Antigens] which results in increased expression of IL6 protein; [Docosahexaenoic Acids co-treated with Eicosapentaenoic Acid] inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; [Lipopolysaccharides co-treated with deoxynivalenol] results in increased expression of IL6 protein; acetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; AKT1 protein affects the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; ATF6 protein affects the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased secretion of IL6 protein]; BMAL1 protein inhibits the reaction [deoxynivalenol results in increased expression of IL6 protein]; Celecoxib inhibits the reaction [deoxynivalenol results in increased expression of IL6 protein]; Curcumin inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; deoxynivalenol promotes the reaction [CREB1 protein modified form binds to IL6 promoter]; deoxynivalenol promotes the reaction [fumonisin B1 results in increased expression of IL6 mRNA]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; Dichlororibofuranosylbenzimidazole inhibits the reaction [deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol promotes the reaction [CREB1 protein modified form binds to IL6 promoter]]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased expression of IL6]; Eicosapentaenoic Acid inhibits the reaction [deoxynivalenol results in increased expression of IL6 protein]; Eicosapentaenoic Acid inhibits the reaction [deoxynivalenol results in increased expression of IL6]; Fatty Acids, Omega-3 inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; Fish Oils inhibits the reaction [deoxynivalenol results in increased expression of IL6 protein]; fumonisin B1 promotes the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; HMOX1 protein inhibits the reaction [deoxynivalenol results in increased expression of IL6 protein]; Indomethacin inhibits the reaction [deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein]]; Indomethacin inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; Indomethacin inhibits the reaction [deoxynivalenol results in increased expression of IL6 protein]; Lipopolysaccharides promotes the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; Lipopolysaccharides promotes the reaction [deoxynivalenol results in increased expression of IL6 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein]]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [deoxynivalenol results in increased expression of IL6 protein]; Poly I-C promotes the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; PTGS2 protein affects the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; PTGS2 protein affects the reaction [deoxynivalenol results in increased expression of IL6 protein]; resiquimod promotes the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; SB 203580 inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; stattic inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; Zymosan promotes the reaction [deoxynivalenol results in increased expression of IL6 mRNA] deoxynivalenol results in increased stability of IL6 mRNA
CTD
PMID:9194413 PMID:9707511 PMID:10344227 PMID:11295263 PMID:11922776 PMID:12604842 PMID:12649040 PMID:14644621 PMID:14690764 PMID:15173396 PMID:15371230 PMID:15570035 PMID:15681167 PMID:16009389 PMID:16364386 PMID:16424113 PMID:16524712 PMID:16687389 PMID:17090620 PMID:18433975 PMID:18614267 PMID:19336499 PMID:19625342 PMID:20702593 PMID:21873375 PMID:22454431 PMID:22968694 PMID:24793808 PMID:24937323 PMID:27757495 PMID:28935500 PMID:31034930 PMID:32416088 PMID:32738333 PMID:33170220 PMID:34400200 PMID:34673182 PMID:35090964 PMID:35381244 PMID:35817260 PMID:35925383 PMID:36309173 PMID:36602574 PMID:38763499 More...
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
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Il7
interleukin 7
decreases expression
ISO
deoxynivalenol results in decreased expression of IL7 mRNA
CTD
PMID:22968694
NCBI chr 2:96,142,523...96,186,282
Ensembl chr 2:96,142,092...96,187,389
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Il9
interleukin 9
multiple interactions
ISO
deoxynivalenol promotes the reaction [Antigens, Dermatophagoides results in increased expression of and results in increased secretion of IL9 protein]
CTD
PMID:33170220
NCBI chr17:8,117,028...8,120,151
Ensembl chr17:8,117,028...8,120,151
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Ilf3
interleukin enhancer binding factor 3
increases expression
ISO
deoxynivalenol results in increased expression of ILF3 protein
CTD
PMID:39638853
NCBI chr 8:28,198,454...28,236,634
Ensembl chr 8:28,198,543...28,236,612
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Inpp5d
inositol polyphosphate-5-phosphatase D
affects phosphorylation
ISO
deoxynivalenol affects the phosphorylation of INPP5D protein
CTD
PMID:23352502
NCBI chr 9:95,735,533...95,840,584
Ensembl chr 9:95,735,530...95,840,589
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Ints11
integrator complex subunit 11
increases expression
ISO
deoxynivalenol results in increased expression of INTS11 protein
CTD
PMID:39638853
NCBI chr 5:171,761,370...171,779,883
Ensembl chr 5:171,761,371...171,779,883
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Irak1
interleukin-1 receptor-associated kinase 1
multiple interactions
ISO
deoxynivalenol inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of IRAK1 protein]
CTD
PMID:26961612
NCBI chr X:156,919,927...156,929,825
Ensembl chr X:156,920,081...156,929,825
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Irf2bp2
interferon regulatory factor 2 binding protein 2
increases expression
ISO
deoxynivalenol results in increased expression of IRF2BP2 mRNA
CTD
PMID:31863870
NCBI chr19:71,456,689...71,462,368
Ensembl chr19:71,456,689...71,462,368
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Ist1
IST1 factor associated with ESCRT-III
increases expression
ISO
deoxynivalenol results in increased expression of IST1 mRNA
CTD
PMID:31863870
NCBI chr19:54,558,353...54,580,551
Ensembl chr19:54,558,353...54,580,491
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Itga10
integrin subunit alpha 10
decreases expression
ISO
deoxynivalenol results in decreased expression of ITGA10 mRNA
CTD
PMID:31863870
NCBI chr 2:186,871,711...186,891,012
Ensembl chr 2:186,871,711...186,891,012
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Itga6
integrin subunit alpha 6
decreases expression
ISO
deoxynivalenol results in decreased expression of ITGA6 protein
CTD
PMID:39638853
NCBI chr 3:77,012,168...77,097,076
Ensembl chr 3:77,017,766...77,097,076
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Itgb2
integrin subunit beta 2
increases expression
ISO
deoxynivalenol results in increased expression of ITGB2 mRNA
CTD
PMID:22968694
NCBI chr20:11,061,009...11,097,242
Ensembl chr20:11,058,492...11,097,182
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Itgbl1
integrin subunit beta like 1
decreases expression
ISO
deoxynivalenol results in decreased expression of ITGBL1 mRNA
CTD
PMID:31863870
NCBI chr15:107,186,792...107,448,335
Ensembl chr15:107,186,689...107,451,098
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Itih2
inter-alpha-trypsin inhibitor heavy chain 2
decreases expression
ISO
deoxynivalenol results in decreased expression of ITIH2 protein
CTD
PMID:39638853
NCBI chr17:73,285,281...73,321,555
Ensembl chr17:73,285,270...73,321,547
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Itih5
inter-alpha-trypsin inhibitor heavy chain 5
decreases expression
ISO
deoxynivalenol results in decreased expression of ITIH5 mRNA
CTD
PMID:31863870
NCBI chr17:73,161,886...73,261,930
Ensembl chr17:73,161,611...73,262,496
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Itm2b
integral membrane protein 2B
decreases expression
ISO
deoxynivalenol results in decreased expression of ITM2B protein
CTD
PMID:39638853
NCBI chr15:54,955,549...54,978,455
Ensembl chr15:54,955,552...54,978,455
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Jak1
Janus kinase 1
increases expression increases phosphorylation
ISO
deoxynivalenol results in increased expression of JAK1 mRNA deoxynivalenol results in increased phosphorylation of JAK1 protein
CTD
PMID:22454431 PMID:36602574
NCBI chr 5:120,895,606...121,004,207
Ensembl chr 5:120,896,046...120,996,758
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Jak2
Janus kinase 2
increases expression multiple interactions
ISO
deoxynivalenol results in increased expression of JAK2 mRNA alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [deoxynivalenol promotes the reaction [IL10 protein results in increased phosphorylation of JAK2 mRNA]]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [deoxynivalenol promotes the reaction [IL10 protein results in increased phosphorylation of JAK2 protein]]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [deoxynivalenol results in increased expression of JAK2 mRNA]; deoxynivalenol promotes the reaction [IL10 protein results in increased phosphorylation of JAK2 mRNA]; deoxynivalenol promotes the reaction [IL10 protein results in increased phosphorylation of JAK2 protein]; stattic inhibits the reaction [deoxynivalenol results in increased expression of JAK2 mRNA]
CTD
PMID:22454431 PMID:38432439
NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:236,408,662...236,468,762
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Jpt1
Jupiter microtubule associated homolog 1
increases expression
ISO
deoxynivalenol results in increased expression of JPT1 protein
CTD
PMID:39638853
NCBI chr10:101,243,428...101,261,464
Ensembl chr10:101,243,424...101,261,469
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Jun
Jun proto-oncogene, AP-1 transcription factor subunit
multiple interactions increases phosphorylation increases activity increases expression affects localization affects activity
ISO
[Cadmium Chloride co-treated with deoxynivalenol] results in increased expression of JUN mRNA; deoxynivalenol results in increased expression of and results in increased phosphorylation of JUN protein deoxynivalenol results in increased phosphorylation of JUN protein deoxynivalenol results in increased activity of JUN protein deoxynivalenol results in increased expression of JUN mRNA; deoxynivalenol results in increased expression of JUN protein deoxynivalenol affects the localization of JUN protein deoxynivalenol affects the activity of JUN protein 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased activity of JUN protein]; 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased phosphorylation of JUN protein]; Celecoxib inhibits the reaction [deoxynivalenol results in increased expression of JUN protein]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased phosphorylation of JUN protein]
CTD
PMID:10662601 PMID:12604842 PMID:15371230 PMID:15681167 PMID:15772366 PMID:16424113 PMID:19360757 PMID:23352502 PMID:23792671 PMID:24937323 PMID:32416088 PMID:33309878 PMID:33890134 More...
NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285
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Junb
JunB proto-oncogene, AP-1 transcription factor subunit
multiple interactions increases expression increases activity affects activity
ISO
4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased activity of JUNB protein] deoxynivalenol results in increased expression of JUNB mRNA [Cadmium Chloride co-treated with deoxynivalenol] results in increased expression of JUNB mRNA deoxynivalenol affects the activity of JUNB protein
CTD
PMID:10662601 PMID:15371230 PMID:15681167 PMID:15772366 PMID:33309878
NCBI chr19:40,081,126...40,082,910
Ensembl chr19:40,073,541...40,085,218
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Jund
JunD proto-oncogene, AP-1 transcription factor subunit
affects activity multiple interactions affects localization increases activity increases expression
ISO
deoxynivalenol affects the activity of JUND protein [Cadmium Chloride co-treated with deoxynivalenol] results in increased expression of JUND mRNA deoxynivalenol affects the localization of JUND protein deoxynivalenol results in increased activity of JUND protein deoxynivalenol results in increased expression of JUND mRNA; deoxynivalenol results in increased expression of JUND protein 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased activity of JUND protein]
CTD
PMID:10662601 PMID:12604842 PMID:15772366 PMID:22846391 PMID:33309878 PMID:33890134 More...
NCBI chr16:18,768,093...18,769,771
Ensembl chr16:18,764,985...18,782,148
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Jup
junction plakoglobin
decreases expression
ISO
deoxynivalenol results in decreased expression of JUP protein
CTD
PMID:39638853
NCBI chr10:85,800,812...85,827,881
Ensembl chr10:85,800,814...85,827,429
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Kat2a
lysine acetyltransferase 2A
multiple interactions
ISO
KAT2A protein affects the reaction [deoxynivalenol results in increased expression of ATF3 protein alternative form]
CTD
PMID:30286430
NCBI chr10:86,132,535...86,140,877
Ensembl chr10:86,132,535...86,140,485
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Kat2b
lysine acetyltransferase 2B
increases expression multiple interactions
ISO
deoxynivalenol results in increased expression of KAT2B protein KAT2B protein affects the reaction [deoxynivalenol results in increased expression of ATF3 protein alternative form]
CTD
PMID:30286430
NCBI chr 9:6,799,101...6,903,616
Ensembl chr 9:6,799,145...6,903,616
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Kbtbd11
kelch repeat and BTB domain containing 11
affects phosphorylation
ISO
deoxynivalenol affects the phosphorylation of KBTBD11 protein
CTD
PMID:23811945
NCBI chr16:81,318,596...81,340,334
Ensembl chr16:81,313,093...81,340,390
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Kcnmb4
potassium calcium-activated channel subfamily M regulatory beta subunit 4
decreases expression
ISO
deoxynivalenol results in decreased expression of KCNMB4 mRNA
CTD
PMID:26763390
NCBI chr 7:53,952,150...54,005,101
Ensembl chr 7:53,949,881...54,005,281
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Kdelr1
KDEL endoplasmic reticulum protein retention receptor 1
decreases expression
ISO
deoxynivalenol results in decreased expression of KDELR1 protein
CTD
PMID:39638853
NCBI chr 1:105,483,598...105,494,587
Ensembl chr 1:105,480,967...105,494,600
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Kdelr3
KDEL endoplasmic reticulum protein retention receptor 3
decreases expression
ISO
deoxynivalenol results in decreased expression of KDELR3 mRNA
CTD
PMID:31863870
NCBI chr 7:112,959,632...112,969,858
Ensembl chr 7:112,959,718...112,969,858
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Kdm4b
lysine demethylase 4B
affects phosphorylation
ISO
deoxynivalenol affects the phosphorylation of KDM4B protein
CTD
PMID:23811945
NCBI chr 9:1,245,885...1,324,384
Ensembl chr 9:1,245,899...1,324,384
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Keap1
Kelch-like ECH-associated protein 1
decreases expression multiple interactions increases expression
ISO
deoxynivalenol results in decreased expression of KEAP1 mRNA Selenomethionine inhibits the reaction [deoxynivalenol results in increased expression of KEAP1 protein]
CTD
PMID:34400200 PMID:38040082
NCBI chr 8:28,044,555...28,054,042
Ensembl chr 8:28,044,555...28,054,042
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Khdc4
KH domain containing 4, pre-mRNA splicing factor
increases expression
ISO
deoxynivalenol results in increased expression of KHDC4 mRNA
CTD
PMID:31863870
NCBI chr 2:176,446,895...176,475,405
Ensembl chr 2:176,446,910...176,475,392
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Khdrbs3
KH RNA binding domain containing, signal transduction associated 3
increases expression
ISO
deoxynivalenol results in increased expression of KHDRBS3 mRNA
CTD
PMID:31863870
NCBI chr 7:102,726,628...102,884,545
Ensembl chr 7:102,726,843...102,884,541
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Kif11
kinesin family member 11
increases expression
ISO
deoxynivalenol results in increased expression of KIF11 mRNA
CTD
PMID:31863870
NCBI chr 1:244,494,916...244,589,250
Ensembl chr 1:244,494,875...244,589,250
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Kif2c
kinesin family member 2C
increases expression
ISO
deoxynivalenol results in increased expression of KIF2C mRNA
CTD
PMID:31863870
NCBI chr 5:135,873,925...135,899,267
Ensembl chr 5:135,873,925...135,899,212
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Kitlg
KIT ligand
increases expression
ISO
deoxynivalenol results in increased expression of KITLG mRNA
CTD
PMID:27757495 PMID:31863870
NCBI chr 7:36,782,621...36,863,796
Ensembl chr 7:36,782,638...36,863,793
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Klf4
KLF transcription factor 4
affects localization affects expression
ISO
deoxynivalenol affects the localization of KLF4 protein deoxynivalenol affects the expression of KLF4 protein
CTD
PMID:33890134
NCBI chr 5:75,074,107...75,079,182
Ensembl chr 5:75,074,236...75,078,592
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Klhl30
kelch-like family member 30
decreases expression
ISO
deoxynivalenol results in decreased expression of KLHL30 mRNA
CTD
PMID:26763390
NCBI chr 9:99,389,982...99,400,295
Ensembl chr 9:99,390,014...99,400,295
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Kmt2a
lysine methyltransferase 2A
multiple interactions increases expression
ISO
AG 1879 inhibits the reaction [deoxynivalenol results in increased expression of KMT2A mRNA]; deoxynivalenol promotes the reaction [SP1 protein binds to KMT2A promoter]; SP1 protein promotes the reaction [deoxynivalenol results in increased expression of KMT2A mRNA]
CTD
PMID:19438726
NCBI chr 8:54,013,547...54,089,219
Ensembl chr 8:54,013,547...54,089,317
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Kpna4
karyopherin subunit alpha 4
increases expression
ISO
deoxynivalenol results in increased expression of KPNA4 protein
CTD
PMID:39638853
NCBI chr 2:155,635,679...155,691,056
Ensembl chr 2:155,634,247...155,691,053
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Krr1
KRR1, small subunit processome component homolog
increases expression
ISO
deoxynivalenol results in increased expression of KRR1 protein
CTD
PMID:39638853
NCBI chr 7:49,361,794...49,374,222
Ensembl chr 7:49,361,901...49,374,216
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Krt18
keratin 18
increases expression
ISO
deoxynivalenol results in increased expression of KRT18 protein
CTD
PMID:33890134 PMID:39638853
NCBI chr 7:135,036,168...135,039,844
Ensembl chr 7:135,035,982...135,039,848 Ensembl chr10:135,035,982...135,039,848
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Krt20
keratin 20
multiple interactions decreases expression
ISO
lauric acid inhibits the reaction [deoxynivalenol results in decreased expression of KRT20 protein]
CTD
PMID:34506767
NCBI chr10:84,880,952...84,890,285
Ensembl chr10:84,880,952...84,890,285
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Ktn1
kinectin 1
increases expression
ISO
deoxynivalenol results in increased expression of KTN1 protein
CTD
PMID:39638853
NCBI chr15:23,392,570...23,485,061
Ensembl chr15:23,394,315...23,482,263
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Lad1
ladinin 1
increases expression
ISO
deoxynivalenol results in increased expression of LAD1 protein
CTD
PMID:39638853
NCBI chr13:49,801,347...49,815,709
Ensembl chr13:49,800,472...49,815,709
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Lama5
laminin subunit alpha 5
decreases expression
ISO
deoxynivalenol results in decreased expression of LAMA5 protein
CTD
PMID:39638853
NCBI chr 3:187,647,904...187,695,974
Ensembl chr 3:187,647,904...187,696,173
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Lamb1
laminin subunit beta 1
decreases expression
ISO
deoxynivalenol results in decreased expression of LAMB1 mRNA
CTD
PMID:31863870
NCBI chr 6:53,562,849...53,630,118
Ensembl chr 6:53,563,073...53,630,760
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Lamc1
laminin subunit gamma 1
decreases expression
ISO
deoxynivalenol results in decreased expression of LAMC1 protein
CTD
PMID:39638853
NCBI chr13:67,924,872...68,051,986
Ensembl chr13:67,924,872...68,051,986
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Laptm4a
lysosomal protein transmembrane 4 alpha
decreases expression
ISO
deoxynivalenol results in decreased expression of LAPTM4A protein
CTD
PMID:39638853
NCBI chr 6:37,438,503...37,456,238
Ensembl chr 6:37,438,121...37,456,223
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Larp4
La ribonucleoprotein 4
increases expression
ISO
deoxynivalenol results in increased expression of LARP4 protein
CTD
PMID:39638853
NCBI chr 7:132,983,276...133,031,514
Ensembl chr 7:132,980,385...133,029,633
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Larp7
La ribonucleoprotein 7, transcriptional regulator
decreases phosphorylation
ISO
deoxynivalenol results in decreased phosphorylation of LARP7 protein
CTD
PMID:23352502
NCBI chr 2:218,672,145...218,687,332
Ensembl chr 2:218,672,208...218,687,308
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Lcn1
lipocalin 1
increases expression
ISO
deoxynivalenol results in increased expression of LCN1 protein
CTD
PMID:33890134
NCBI chr 3:29,930,943...29,935,418
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Lcp1
lymphocyte cytosolic protein 1
increases phosphorylation affects phosphorylation
ISO
deoxynivalenol results in increased phosphorylation of LCP1 protein deoxynivalenol affects the phosphorylation of LCP1 protein
CTD
PMID:23352502 PMID:23811945
NCBI chr15:56,846,375...56,954,090
Ensembl chr15:56,847,433...56,954,092
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Lgals3bp
galectin 3 binding protein
decreases expression
ISO
deoxynivalenol results in decreased expression of LGALS3BP protein
CTD
PMID:33890134 PMID:39638853
NCBI chr10:104,118,510...104,127,848
Ensembl chr10:104,118,510...104,127,848
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Lgr5
leucine rich repeat containing G protein coupled receptor 5
multiple interactions decreases expression
ISO
lauric acid inhibits the reaction [deoxynivalenol results in decreased expression of LGR5 protein]
CTD
PMID:34506767
NCBI chr 7:52,973,151...53,107,964
Ensembl chr 7:52,974,332...53,108,163
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Lhcgr
luteinizing hormone/choriogonadotropin receptor
multiple interactions
ISO
[Colforsin co-treated with deoxynivalenol] results in increased expression of LHCGR mRNA
CTD
PMID:26783879
NCBI chr 6:11,415,361...11,480,834
Ensembl chr 6:11,415,415...11,478,061
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Lig1
DNA ligase 1
affects phosphorylation
ISO
deoxynivalenol affects the phosphorylation of LIG1 protein
CTD
PMID:23811945
NCBI chr 1:83,243,043...83,281,707
Ensembl chr 1:83,219,545...83,281,708
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Lin28b
lin-28 homolog B
increases expression
ISO
deoxynivalenol results in increased expression of LIN28B protein
CTD
PMID:39638853
NCBI chr20:50,447,700...50,547,135
Ensembl chr20:50,450,971...50,541,968
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Lipa
lipase A, lysosomal acid type
decreases expression
ISO
deoxynivalenol results in decreased expression of LIPA protein
CTD
PMID:33890134 PMID:39638853
NCBI chr 1:241,437,524...241,470,936
Ensembl chr 1:241,437,524...241,470,740
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Llph
LLP homolog, long-term synaptic facilitation factor
increases expression
ISO
deoxynivalenol results in increased expression of LLPH protein
CTD
PMID:39638853
NCBI chr 7:57,620,925...57,625,924
Ensembl chr 7:57,620,993...57,625,925
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Lmna
lamin A/C
affects phosphorylation decreases phosphorylation
ISO
deoxynivalenol affects the phosphorylation of LMNA protein deoxynivalenol results in decreased phosphorylation of LMNA protein
CTD
PMID:23352502 PMID:23811945
NCBI chr 2:176,237,564...176,265,301
Ensembl chr 2:176,237,564...176,288,072
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Lmnb1
lamin B1
increases phosphorylation
ISO
deoxynivalenol results in increased phosphorylation of LMNB1 protein
CTD
PMID:23811945
NCBI chr18:52,373,939...52,413,284
Ensembl chr18:52,373,757...52,413,283
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Lmo2
LIM domain only 2
decreases expression
ISO
deoxynivalenol results in decreased expression of LMO2 mRNA
CTD
PMID:26763390
NCBI chr 3:110,810,162...110,832,895
Ensembl chr 3:110,809,912...110,833,075
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Loxl3
lysyl oxidase-like 3
decreases expression
ISO
deoxynivalenol results in decreased expression of LOXL3 mRNA
CTD
PMID:31863870
NCBI chr 4:117,098,358...117,114,673
Ensembl chr 4:117,099,635...117,115,046
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Lpcat3
lysophosphatidylcholine acyltransferase 3
multiple interactions decreases expression
ISO
Selenomethionine inhibits the reaction [deoxynivalenol results in decreased expression of LPCAT3 protein]
CTD
PMID:38040082
NCBI chr 4:159,154,690...159,196,176
Ensembl chr 4:159,154,158...159,196,358
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Lpxn
leupaxin
decreases phosphorylation
ISO
deoxynivalenol results in decreased phosphorylation of LPXN protein
CTD
PMID:23352502
NCBI chr 1:219,353,319...219,387,743
Ensembl chr 1:219,353,708...219,387,742
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Lrp1
LDL receptor related protein 1
decreases expression
ISO
deoxynivalenol results in decreased expression of LRP1 protein
CTD
PMID:39638853
NCBI chr 7:65,265,639...65,346,196
Ensembl chr 7:65,265,639...65,346,196
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Lrrc59
leucine rich repeat containing 59
increases expression
ISO
deoxynivalenol results in increased expression of LRRC59 protein
CTD
PMID:39638853
NCBI chr10:80,069,162...80,083,820
Ensembl chr10:80,069,120...80,084,079
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Lsm3
LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated
increases expression
ISO
deoxynivalenol results in increased expression of LSM3 protein
CTD
PMID:39638853
NCBI chr 4:125,578,185...125,584,429
Ensembl chr 4:125,578,185...125,584,429
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Lsp1
lymphocyte-specific protein 1
affects phosphorylation decreases expression increases phosphorylation
ISO
deoxynivalenol affects the phosphorylation of LSP1 protein deoxynivalenol results in decreased expression of LSP1 mRNA deoxynivalenol results in increased phosphorylation of LSP1 protein
CTD
PMID:23352502 PMID:23811945 PMID:31863870
NCBI chr 1:207,044,157...207,077,891
Ensembl chr 1:207,044,159...207,077,893
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Lss
lanosterol synthase
decreases expression
ISO
deoxynivalenol results in decreased expression of LSS protein
CTD
PMID:39638853
NCBI chr20:12,090,641...12,118,230
Ensembl chr20:12,073,543...12,118,253
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Lta
lymphotoxin alpha
increases expression
ISO
deoxynivalenol results in increased expression of LTA mRNA
CTD
PMID:22968694
NCBI chr20:3,622,291...3,625,852
Ensembl chr20:3,623,527...3,625,533
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Ltb
lymphotoxin beta
decreases expression
ISO
deoxynivalenol results in decreased expression of LTB mRNA
CTD
PMID:22968694
NCBI chr20:3,632,209...3,634,054
Ensembl chr20:3,632,210...3,634,054
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Ltbp2
latent transforming growth factor beta binding protein 2
decreases expression
ISO
deoxynivalenol results in decreased expression of LTBP2 mRNA
CTD
PMID:31863870
NCBI chr 6:110,161,029...110,261,586
Ensembl chr 6:110,161,029...110,257,298
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Luc7l1
LUC7 pre-mRNA splicing factor like 1
increases expression
ISO
deoxynivalenol results in increased expression of LUC7L protein
CTD
PMID:39638853
NCBI chr10:15,777,837...15,811,586
Ensembl chr10:15,777,829...15,817,940
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Luc7l3
LUC7 pre-mRNA splicing factor like 3
increases expression
ISO
deoxynivalenol results in increased expression of LUC7L3 protein
CTD
PMID:39638853
NCBI chr10:79,737,457...79,773,478
Ensembl chr10:79,736,853...79,773,429
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Lyar
Ly1 antibody reactive
increases expression
ISO
deoxynivalenol results in increased expression of LYAR protein
CTD
PMID:39638853
NCBI chr14:76,789,193...76,802,973
Ensembl chr14:76,789,200...76,802,765
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Lyz2
lysozyme 2
multiple interactions decreases expression
ISO
lauric acid inhibits the reaction [deoxynivalenol results in decreased expression of LYZ protein]
CTD
PMID:34506767
NCBI chr 7:54,792,715...54,798,060
Ensembl chr 7:54,792,716...54,798,011
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Macroh2a1
macroH2A.1 histone
increases expression
ISO
deoxynivalenol results in increased expression of MACROH2A1 protein
CTD
PMID:39638853
NCBI chr17:8,484,340...8,547,268
Ensembl chr17:8,484,246...8,547,257
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Maff
MAF bZIP transcription factor F
increases expression
ISO
deoxynivalenol results in increased expression of MAFF mRNA
CTD
PMID:24247028
NCBI chr 7:112,792,787...112,804,139
Ensembl chr 7:112,791,416...112,804,147
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Mall
mal, T-cell differentiation protein-like
decreases expression
ISO
deoxynivalenol results in decreased expression of MALL mRNA
CTD
PMID:31863870
NCBI chr 3:135,381,180...135,404,136
Ensembl chr 3:135,377,410...135,404,066
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Maoa
monoamine oxidase A
decreases expression
ISO
deoxynivalenol results in decreased expression of MAOA protein
CTD
PMID:39638853
NCBI chr X:8,615,239...8,681,372
Ensembl chr X:8,615,239...8,682,631
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Map1lc3b
microtubule-associated protein 1 light chain 3 beta
increases expression decreases expression multiple interactions
ISO
deoxynivalenol results in increased expression of MAP1LC3B mRNA deoxynivalenol results in decreased expression of MAP1LC3B protein 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of MAP1LC3B mRNA]]; 6-formylindolo(3,2-b)carbazole promotes the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of MAP1LC3B mRNA]]; Selenomethionine inhibits the reaction [deoxynivalenol results in decreased expression of MAP1LC3B protein]; sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of MAP1LC3B mRNA]
CTD
PMID:34677630 PMID:35381244 PMID:38040082
NCBI chr19:66,571,631...66,582,270
Ensembl chr19:66,574,407...66,584,358 Ensembl chr16:66,574,407...66,584,358
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Map2k4
mitogen activated protein kinase kinase 4
increases phosphorylation multiple interactions
ISO
deoxynivalenol results in increased phosphorylation of MAP2K4 protein Celecoxib inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAP2K4 protein]
CTD
PMID:32416088
NCBI chr10:50,842,348...50,947,063
Ensembl chr10:50,844,034...50,947,185
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Map2k6
mitogen-activated protein kinase kinase 6
multiple interactions increases phosphorylation
ISO
AG 1879 inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAP2K6 protein]
CTD
PMID:20181660
NCBI chr10:95,872,747...95,987,747
Ensembl chr10:95,872,546...95,987,721
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Map3k5
mitogen-activated protein kinase kinase kinase 5
multiple interactions increases phosphorylation
ISO
AG 1879 inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAP3K5 protein]
CTD
PMID:20181660
NCBI chr 1:16,505,387...16,723,899
Ensembl chr 1:16,505,596...16,723,898
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Map4
microtubule-associated protein 4
decreases phosphorylation
ISO
deoxynivalenol results in decreased phosphorylation of MAP4 protein
CTD
PMID:23811945
NCBI chr 8:118,800,393...118,942,805
Ensembl chr 8:118,804,022...118,942,805
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Mapk1
mitogen activated protein kinase 1
multiple interactions increases phosphorylation
ISO
4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK1 protein]; AG 1879 inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK1 protein]; Celecoxib inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK1 protein]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK1 protein]; Eicosapentaenoic Acid inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK1 protein]; Fish Oils inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK1 protein]; Lipopolysaccharides inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK1 protein] [deoxynivalenol results in increased phosphorylation of MAPK1 protein] which results in increased expression of CXCL8 protein; deoxynivalenol results in increased phosphorylation of and results in increased activity of MAPK1 protein; MAPK1 protein promotes the reaction [deoxynivalenol results in increased expression of PPARG mRNA]
CTD
PMID:12377986 PMID:12604842 PMID:14644621 PMID:14690764 PMID:15570035 PMID:15772366 PMID:15976193 PMID:16009389 PMID:16424113 PMID:17707346 PMID:18006205 PMID:18485432 PMID:18502741 PMID:19360757 PMID:20633634 PMID:23352502 PMID:23811945 PMID:24937323 PMID:32416088 PMID:37705238 More...
NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
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Mapk12
mitogen-activated protein kinase 12
decreases expression
ISO
deoxynivalenol results in decreased expression of MAPK12 mRNA
CTD
PMID:31863870
NCBI chr 7:122,085,647...122,096,307
Ensembl chr 7:122,085,913...122,096,307
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Mapk14
mitogen activated protein kinase 14
multiple interactions increases expression increases phosphorylation
ISO
deoxynivalenol results in increased phosphorylation of and results in increased activity of MAPK14 protein deoxynivalenol results in increased expression of MAPK14 mRNA deoxynivalenol results in increased phosphorylation of MAPK14 protein
CTD
PMID:15976193 PMID:16364386 PMID:20702593
NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294
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Mapk3
mitogen activated protein kinase 3
multiple interactions increases phosphorylation
ISO
[deoxynivalenol results in increased phosphorylation of MAPK3 protein] which results in increased expression of CXCL8 protein; deoxynivalenol results in increased phosphorylation of and results in increased activity of MAPK3 protein; MAPK3 protein promotes the reaction [deoxynivalenol results in increased expression of PPARG mRNA] 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK3 protein]; AG 1879 inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK3 protein]; Celecoxib inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK3 protein]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK3 protein]; Eicosapentaenoic Acid inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK3 protein]; Fish Oils inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK3 protein]; Lipopolysaccharides inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK3 protein]
CTD
PMID:12377986 PMID:12604842 PMID:14644621 PMID:14690764 PMID:15570035 PMID:15772366 PMID:15976193 PMID:16009389 PMID:16424113 PMID:17707346 PMID:18006205 PMID:18485432 PMID:18502741 PMID:19360757 PMID:20633634 PMID:23352502 PMID:23811945 PMID:24937323 PMID:32416088 PMID:37705238 More...
NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
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Mapk8
mitogen-activated protein kinase 8
decreases activity increases phosphorylation multiple interactions
ISO
deoxynivalenol results in decreased activity of MAPK8 protein deoxynivalenol results in increased phosphorylation of MAPK8 protein 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK8 protein]; AG 1879 inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK8 protein]; Celecoxib inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK8 protein]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK8 protein]; Eicosapentaenoic Acid inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK8 protein]; Fish Oils inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK8 protein] [deoxynivalenol results in increased expression of DUSP1 protein] which results in decreased activity of MAPK8 protein; deoxynivalenol results in increased phosphorylation of and results in increased activity of MAPK8 protein
CTD
PMID:12377986 PMID:12604842 PMID:14644621 PMID:14690764 PMID:15570035 PMID:15772366 PMID:16424113 PMID:18485432 PMID:18502741 PMID:19360757 PMID:20708668 PMID:23352502 PMID:32416088 PMID:37705238 More...
NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427
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Mapk9
mitogen-activated protein kinase 9
decreases activity increases phosphorylation decreases phosphorylation decreases expression multiple interactions
ISO
deoxynivalenol results in decreased activity of MAPK9 protein deoxynivalenol results in increased phosphorylation of MAPK9 protein deoxynivalenol results in decreased phosphorylation of MAPK9 protein deoxynivalenol results in decreased expression of MAPK9 mRNA 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK9 protein]; AG 1879 inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK9 protein]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK9 protein]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK9 protein]; Eicosapentaenoic Acid inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK9 protein]; Fish Oils inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK9 protein] [deoxynivalenol results in increased expression of DUSP1 protein] which results in decreased activity of MAPK9 protein; deoxynivalenol results in increased phosphorylation of and results in increased activity of MAPK9 protein
CTD
PMID:12377986 PMID:12604842 PMID:14644621 PMID:14690764 PMID:15371230 PMID:15570035 PMID:15772366 PMID:16424113 PMID:18485432 PMID:18502741 PMID:19360757 PMID:20633634 PMID:20708668 PMID:23352502 PMID:23811945 More...
NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,670,756...34,712,228
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Marcks
myristoylated alanine rich protein kinase C substrate
increases phosphorylation decreases expression
ISO
deoxynivalenol results in increased phosphorylation of MARCKS protein deoxynivalenol results in decreased expression of MARCKS protein
CTD
PMID:23811945 PMID:39638853
NCBI chr20:42,240,185...42,245,882
Ensembl chr20:42,240,185...42,245,882
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Mcfd2
multiple coagulation factor deficiency 2, ER cargo receptor complex subunit
decreases expression
ISO
deoxynivalenol results in decreased expression of MCFD2 protein
CTD
PMID:39638853
NCBI chr 6:13,028,036...13,039,388
Ensembl chr 6:13,016,104...13,039,379
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Mdm2
MDM2 proto-oncogene
increases expression
ISO
deoxynivalenol results in increased expression of MDM2 mRNA
CTD
PMID:31863870
NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:55,176,560...55,200,791
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Mdm4
MDM4 regulator of p53
increases expression
ISO
deoxynivalenol results in increased expression of MDM4 mRNA
CTD
PMID:22846391
NCBI chr13:46,922,236...47,068,241
Ensembl chr13:46,958,298...47,026,372
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Meis3
Meis homeobox 3
decreases response to substance decreases expression
ISO
MEIS3 protein results in decreased susceptibility to deoxynivalenol deoxynivalenol results in decreased expression of MEIS3 mRNA
CTD
PMID:26763390
NCBI chr 1:85,986,602...86,000,873
Ensembl chr 1:85,990,050...86,000,873
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Met
MET proto-oncogene, receptor tyrosine kinase
affects phosphorylation
ISO
deoxynivalenol affects the phosphorylation of MET protein
CTD
PMID:23811945
NCBI chr 4:46,756,823...46,864,041
Ensembl chr 4:46,756,506...46,870,821
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Mettl14
methyltransferase 14, N6-adenosine-methyltransferase non-catalytic subunit
increases expression
ISO
deoxynivalenol results in increased expression of METTL14 mRNA
CTD
PMID:31863870
NCBI chr 2:214,215,165...214,231,412
Ensembl chr 2:214,215,165...214,231,412
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Micall1
MICAL-like 1
decreases phosphorylation
ISO
deoxynivalenol results in decreased phosphorylation of MICALL1 protein
CTD
PMID:33890134
NCBI chr 7:112,557,192...112,587,618
Ensembl chr 7:112,557,192...112,587,618
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Minpp1
multiple inositol-polyphosphate phosphatase 1
decreases expression
ISO
deoxynivalenol results in decreased expression of MINPP1 protein
CTD
PMID:39638853
NCBI chr 1:239,766,809...239,793,023
Ensembl chr 1:239,767,286...239,793,015
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Mir221
microRNA 221
multiple interactions
ISO
[Zearalenone co-treated with deoxynivalenol] results in decreased expression of MIR221 mRNA
CTD
PMID:35090964
NCBI chr X:6,023,182...6,023,290
Ensembl chr X:6,023,182...6,023,290
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Mki67
marker of proliferation Ki-67
increases phosphorylation multiple interactions increases expression
ISO
deoxynivalenol results in increased phosphorylation of MKI67 protein Celecoxib inhibits the reaction [deoxynivalenol results in increased expression of MKI67 protein] deoxynivalenol results in increased expression of MKI67 mRNA; deoxynivalenol results in increased expression of MKI67 protein
CTD
PMID:23352502 PMID:23811945 PMID:31863870 PMID:32416088 PMID:39638853
NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:199,926,150...199,952,593
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Mknk2
MAPK interacting serine/threonine kinase 2
affects phosphorylation decreases expression
ISO
deoxynivalenol affects the phosphorylation of MKNK2 protein deoxynivalenol results in decreased expression of MKNK2 mRNA
CTD
PMID:23811945 PMID:31863870
NCBI chr 7:9,690,385...9,701,527
Ensembl chr 7:9,690,421...9,701,529
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Mmut
methylmalonyl-CoA mutase
decreases expression
ISO
deoxynivalenol results in decreased expression of MMUT protein
CTD
PMID:33890134 PMID:39638853
NCBI chr 9:27,425,935...27,454,202
Ensembl chr 9:27,425,935...27,454,342
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Mpo
myeloperoxidase
increases activity
ISO
deoxynivalenol results in increased activity of MPO protein
CTD
PMID:24937323
NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056
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Mrap2
melanocortin 2 receptor accessory protein 2
decreases expression
ISO
deoxynivalenol results in decreased expression of MRAP2 mRNA
CTD
PMID:31863870
NCBI chr 8:96,968,239...97,024,581
Ensembl chr 8:96,988,079...97,024,579
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Mrm1
mitochondrial rRNA methyltransferase 1
increases expression
ISO
deoxynivalenol results in increased expression of MRM1 protein
CTD
PMID:39638853
NCBI chr10:70,187,842...70,194,785
Ensembl chr10:70,188,748...70,194,131
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Mrpl12
mitochondrial ribosomal protein L12
increases expression
ISO
deoxynivalenol results in increased expression of MRPL12 protein
CTD
PMID:39638853
NCBI chr10:106,256,746...106,261,249
Ensembl chr10:106,256,547...106,263,088
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Mrpl28
mitochondrial ribosomal protein L28
increases expression
ISO
deoxynivalenol results in increased expression of MRPL28 protein
CTD
PMID:39638853
NCBI chr10:15,653,006...15,656,062
Ensembl chr10:15,653,179...15,666,971
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Mrpl39
mitochondrial ribosomal protein L39
increases expression
ISO
deoxynivalenol results in increased expression of MRPL39 mRNA
CTD
PMID:31863870
NCBI chr11:37,266,116...37,281,612
Ensembl chr11:37,257,696...37,281,544
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Mrps18b
mitochondrial ribosomal protein S18B
increases expression
ISO
deoxynivalenol results in increased expression of MRPS18B mRNA
CTD
PMID:31863870
NCBI chr20:2,842,978...2,849,065
Ensembl chr20:2,842,528...2,849,065
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Mrps22
mitochondrial ribosomal protein S22
increases expression
ISO
deoxynivalenol results in increased expression of MRPS22 mRNA
CTD
PMID:31863870
NCBI chr 8:108,063,468...108,076,638
Ensembl chr 8:108,063,471...108,076,638
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Mrps30
mitochondrial ribosomal protein S30
increases expression
ISO
deoxynivalenol results in increased expression of MRPS30 mRNA
CTD
PMID:24247028 PMID:31863870
NCBI chr 2:52,189,049...52,196,136
Ensembl chr 2:52,189,058...52,195,904
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Mrps31
mitochondrial ribosomal protein S31
increases expression
ISO
deoxynivalenol results in increased expression of MRPS31 mRNA
CTD
PMID:31863870
NCBI chr16:76,303,807...76,332,970
Ensembl chr16:76,301,645...76,333,065
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Mrto4
MRT4 homolog, ribosome maturation factor
increases expression
ISO
deoxynivalenol results in increased expression of MRTO4 protein
CTD
PMID:39638853
NCBI chr 5:156,884,985...156,891,738
Ensembl chr 5:156,884,985...156,891,738
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Msh6
mutS homolog 6
decreases expression
ISO
deoxynivalenol results in decreased expression of MSH6 protein
CTD
PMID:39638853
NCBI chr 6:12,316,190...12,333,505
Ensembl chr 6:12,316,198...12,333,844
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Msx2
msh homeobox 2
increases expression
ISO
deoxynivalenol results in increased expression of MSX2 mRNA
CTD
PMID:31863870
NCBI chr17:11,102,284...11,107,949
Ensembl chr17:11,102,247...11,107,945
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Mta1
metastasis associated 1
increases expression
ISO
deoxynivalenol results in increased expression of MTA1 protein
CTD
PMID:39638853
NCBI chr 6:137,999,845...138,038,696
Ensembl chr 6:137,999,915...138,038,696
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Mta2
metastasis associated 1 family, member 2
increases expression
ISO
deoxynivalenol results in increased expression of MTA2 protein
CTD
PMID:39638853
NCBI chr 1:215,267,286...215,276,008
Ensembl chr 1:215,267,046...215,276,062
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Mta3
metastasis associated 1 family, member 3
affects phosphorylation
ISO
deoxynivalenol affects the phosphorylation of MTA3 protein
CTD
PMID:23352502
NCBI chr 6:16,619,575...16,739,732
Ensembl chr 6:16,621,998...16,739,485
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Mtdh
metadherin
affects phosphorylation
ISO
deoxynivalenol affects the phosphorylation of LYRIC protein
CTD
PMID:23352502
NCBI chr 7:67,192,592...67,250,819
Ensembl chr 7:67,192,393...67,249,584
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Mthfd2
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
decreases expression
ISO
deoxynivalenol results in decreased expression of MTHFD2 mRNA
CTD
PMID:31863870
NCBI chr 4:117,368,833...117,380,350
Ensembl chr 4:117,368,835...117,380,350
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Mtor
mechanistic target of rapamycin kinase
multiple interactions decreases phosphorylation
ISO
lauric acid inhibits the reaction [deoxynivalenol results in decreased phosphorylation of MTOR protein]
CTD
PMID:34506767
NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:164,167,928...164,277,435
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Mtrex
Mtr4 exosome RNA helicase
increases expression
ISO
deoxynivalenol results in increased expression of MTREX mRNA; deoxynivalenol results in increased expression of MTREX protein
CTD
PMID:31863870 PMID:39638853
NCBI chr 2:46,233,528...46,293,827
Ensembl chr 2:46,194,647...46,293,827
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Mttp
microsomal triglyceride transfer protein
decreases expression
ISO
deoxynivalenol results in decreased expression of MTTP protein
CTD
PMID:39638853
NCBI chr 2:229,286,501...229,327,650
Ensembl chr 2:229,286,501...229,327,650
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Muc16
mucin 16, cell surface associated
affects phosphorylation
ISO
deoxynivalenol affects the phosphorylation of MUC16 protein
CTD
PMID:23811945
NCBI chr 8:24,440,840...24,644,494
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Muc2
mucin 2, oligomeric mucus/gel-forming
multiple interactions decreases expression
ISO
lauric acid inhibits the reaction [deoxynivalenol results in decreased expression of MUC2 protein]
CTD
PMID:34506767
NCBI chr 1:206,225,775...206,261,280
Ensembl chr 1:206,229,035...206,261,280
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Muc5ac
mucin 5AC, oligomeric mucus/gel-forming
increases expression multiple interactions
ISO
deoxynivalenol results in increased expression of MUC5AC mRNA deoxynivalenol results in increased expression of and results in increased secretion of MUC5AC protein
CTD
PMID:24496642
NCBI chr 1:206,293,717...206,326,006
Ensembl chr 1:206,293,869...206,326,006
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Muc5b
mucin 5B, oligomeric mucus/gel-forming
increases expression multiple interactions
ISO
deoxynivalenol results in increased expression of MUC5B mRNA deoxynivalenol results in increased expression of and results in increased secretion of MUC5B protein
CTD
PMID:24496642
NCBI chr 1:206,346,400...206,378,367
Ensembl chr 1:206,346,400...206,378,367
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Mvk
mevalonate kinase
decreases expression
ISO
deoxynivalenol results in decreased expression of MVK protein
CTD
PMID:39638853
NCBI chr12:47,802,002...47,819,503
Ensembl chr12:47,802,002...47,819,503
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Mybbp1a
MYB binding protein 1a
decreases phosphorylation increases expression
ISO
deoxynivalenol results in decreased phosphorylation of MYBBP1A protein deoxynivalenol results in increased expression of MYBBP1A protein
CTD
PMID:23352502 PMID:39638853
NCBI chr10:57,555,458...57,565,819
Ensembl chr10:57,555,452...57,566,041
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Myc
MYC proto-oncogene, bHLH transcription factor
increases expression
ISO
deoxynivalenol results in increased expression of MYC mRNA
CTD
PMID:24247028
NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028
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Mycn
MYCN proto-oncogene, bHLH transcription factor
affects phosphorylation
ISO
deoxynivalenol affects the phosphorylation of MYCN protein
CTD
PMID:23352502
NCBI chr 6:41,446,683...41,452,584
Ensembl chr 6:41,446,684...41,452,508
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Myd88
MYD88, innate immune signal transduction adaptor
multiple interactions increases expression
ISO
deoxynivalenol inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of MYD88 protein] deoxynivalenol results in increased expression of MYD88 mRNA; deoxynivalenol results in increased expression of MYD88 protein
CTD
PMID:26961612 PMID:34400200
NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:127,952,161...127,956,230
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Myh11
myosin heavy chain 11
decreases phosphorylation
ISO
deoxynivalenol results in decreased phosphorylation of MYH11 protein
CTD
PMID:23811945
NCBI chr10:1,250,554...1,345,681
Ensembl chr10:1,263,194...1,345,678
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Myh9
myosin, heavy chain 9
affects phosphorylation increases phosphorylation
ISO
deoxynivalenol affects the phosphorylation of MYH9 protein deoxynivalenol results in increased phosphorylation of MYH9 protein
CTD
PMID:23352502 PMID:23811945
NCBI chr 7:111,224,291...111,304,963
Ensembl chr 7:111,224,291...111,304,963
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Myl9
myosin light chain 9
multiple interactions increases expression
ISO
Curcumin inhibits the reaction [deoxynivalenol results in increased expression of MYL9 protein modified form]
CTD
PMID:35817260
NCBI chr 3:165,742,020...165,748,409
Ensembl chr 3:165,742,046...165,748,410
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Mylk
myosin light chain kinase
increases expression multiple interactions
ISO
deoxynivalenol results in increased expression of MYLK mRNA; deoxynivalenol results in increased expression of MYLK protein Curcumin inhibits the reaction [deoxynivalenol results in increased expression of MYLK mRNA]; Curcumin inhibits the reaction [deoxynivalenol results in increased expression of MYLK protein]
CTD
PMID:35817260
NCBI chr11:79,288,243...79,535,450
Ensembl chr11:79,288,243...79,535,659
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Myo5c
myosin VC
decreases expression
ISO
deoxynivalenol results in decreased expression of MYO5C mRNA
CTD
PMID:26763390
NCBI chr 8:84,870,031...84,946,996
Ensembl chr 8:84,870,043...84,946,996
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Mzf1
myeloid zinc finger 1
decreases expression
ISO
deoxynivalenol results in decreased expression of MZF1 protein
CTD
PMID:33890134
NCBI chr 1:82,742,709...82,755,069
Ensembl chr 1:82,742,726...82,753,820
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Naglu
N-acetyl-alpha-glucosaminidase
decreases expression
ISO
deoxynivalenol results in decreased expression of NAGLU mRNA
CTD
PMID:31863870
NCBI chr10:86,501,864...86,509,333
Ensembl chr10:86,501,836...86,509,315
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Nampt
nicotinamide phosphoribosyltransferase
increases expression
ISO
deoxynivalenol results in increased expression of NAMPT mRNA
CTD
PMID:31863870
NCBI chr 6:55,152,756...55,189,547
Ensembl chr 6:55,151,926...55,189,544
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Nanos1
nanos C2HC-type zinc finger 1
decreases expression
ISO
deoxynivalenol results in decreased expression of NANOS1 mRNA
CTD
PMID:31863870
NCBI chr 1:269,883,713...269,887,611
Ensembl chr 1:269,883,536...269,895,417
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Ncl
nucleolin
affects phosphorylation increases expression
ISO
deoxynivalenol affects the phosphorylation of NCL protein deoxynivalenol results in increased expression of NCL protein
CTD
PMID:23352502 PMID:39638853
NCBI chr 9:94,447,559...94,456,083
Ensembl chr 9:94,446,682...94,456,083
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Ncoa4
nuclear receptor coactivator 4
decreases expression
ISO
deoxynivalenol results in decreased expression of NCOA4 mRNA
CTD
PMID:39983889
NCBI chr16:7,395,502...7,415,846
Ensembl chr16:7,401,802...7,415,840
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Ncoa5
nuclear receptor coactivator 5
increases expression
ISO
deoxynivalenol results in increased expression of NCOA5 protein
CTD
PMID:39638853
NCBI chr 3:174,155,731...174,188,862
Ensembl chr 3:174,155,741...174,188,862
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Ndc80
NDC80 kinetochore complex component
increases expression
ISO
deoxynivalenol results in increased expression of NDC80 mRNA
CTD
PMID:31863870
NCBI chr 9:118,853,806...118,887,582
Ensembl chr 9:118,853,806...118,887,568
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Ndufb7
NADH:ubiquinone oxidoreductase subunit B7
decreases expression
ISO
deoxynivalenol results in decreased expression of NDUFB7 protein
CTD
PMID:33890134
NCBI chr19:41,472,953...41,477,291
Ensembl chr19:41,472,953...41,477,291
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Ndufb8
NADH:ubiquinone oxidoreductase subunit B8
decreases expression
ISO
deoxynivalenol results in decreased expression of NDUFB8 protein
CTD
PMID:33890134
NCBI chr 1:253,357,878...253,362,936
Ensembl chr 1:253,357,841...253,362,936
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Ndufb9
NADH:ubiquinone oxidoreductase subunit B9
decreases expression
ISO
deoxynivalenol results in decreased expression of NDUFB9 protein
CTD
PMID:33890134
NCBI chr 7:92,370,423...92,376,841
Ensembl chr 7:92,370,467...92,379,955
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Ndufs4
NADH:ubiquinone oxidoreductase subunit S4
decreases expression
ISO
deoxynivalenol results in decreased expression of NDUFS4 protein
CTD
PMID:33890134
NCBI chr 2:47,684,420...47,794,914
Ensembl chr 2:47,684,406...47,794,931
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Ndufs5
NADH:ubiquinone oxidoreductase subunit S5
decreases expression
ISO
deoxynivalenol results in decreased expression of NDUFS5 protein
CTD
PMID:33890134
NCBI chr 5:141,258,828...141,264,552
Ensembl chr 2:184,849,197...185,028,909 Ensembl chr 5:184,849,197...185,028,909 Ensembl chr14:184,849,197...185,028,909
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Ndufs7
NADH:ubiquinone oxidoreductase core subunit S7
decreases expression
ISO
deoxynivalenol results in decreased expression of NDUFS7 protein
CTD
PMID:33890134
NCBI chr 7:10,103,226...10,110,862
Ensembl chr 7:10,103,227...10,110,691
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Ndufv3
NADH:ubiquinone oxidoreductase subunit V3
decreases expression
ISO
deoxynivalenol results in decreased expression of NDUFV3 protein
CTD
PMID:33890134
NCBI chr20:9,613,786...9,622,941
Ensembl chr13:48,468,224...48,488,847 Ensembl chr20:48,468,224...48,488,847
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Nedd4l
NEDD4 like E3 ubiquitin protein ligase
increases expression
ISO
deoxynivalenol results in increased expression of NEDD4L mRNA
CTD
PMID:31863870
NCBI chr18:60,663,918...60,996,824
Ensembl chr18:60,663,970...60,996,824
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Neu1
neuraminidase 1
decreases expression
ISO
deoxynivalenol results in decreased expression of NEU1 protein
CTD
PMID:39638853
NCBI chr20:3,902,120...3,906,383
Ensembl chr20:3,902,120...3,906,383
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Nfatc1
nuclear factor of activated T-cells 1
affects localization
ISO
deoxynivalenol affects the localization of NFATC1 protein
CTD
PMID:21074547 PMID:22846391
NCBI chr18:76,321,386...76,430,997
Ensembl chr18:76,321,386...76,430,990
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Nfe2l2
NFE2 like bZIP transcription factor 2
increases activity multiple interactions decreases expression increases expression
ISO
deoxynivalenol analog results in increased activity of NFE2L2 protein; deoxynivalenol results in increased activity of NFE2L2 protein Selenomethionine inhibits the reaction [deoxynivalenol results in increased expression of NFE2L2 protein] deoxynivalenol results in decreased expression of NFE2L2 mRNA 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in increased expression of NFE2L2 mRNA]; Resveratrol inhibits the reaction [deoxynivalenol results in decreased expression of NFE2L2 protein] deoxynivalenol results in increased expression of NFE2L2 mRNA; deoxynivalenol results in increased expression of NFE2L2 protein
CTD
PMID:30244016 PMID:34400200 PMID:34677630 PMID:37419272 PMID:38040082 PMID:39983889 More...
NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090
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Nfkb1
nuclear factor kappa B subunit 1
multiple interactions increases expression increases activity affects localization
ISO
4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased activity of NFKB1 protein]; deoxynivalenol results in decreased activity of [NFKB1 protein binds to NFKB1 protein]; deoxynivalenol results in decreased activity of [REL protein binds to NFKB1 protein] deoxynivalenol results in increased expression of NFKB1 mRNA deoxynivalenol affects the localization of NFKB1 protein
CTD
PMID:8887449 PMID:12604842 PMID:15772366 PMID:35314294
NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088
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Nfkb2
nuclear factor kappa B subunit 2
increases expression multiple interactions
ISO
deoxynivalenol results in increased expression of NFKB2 mRNA deoxynivalenol inhibits the reaction [NFKB2 protein binds to CXCL8 promoter]
CTD
PMID:17636245 PMID:22846391
NCBI chr 1:255,106,010...255,114,649
Ensembl chr 1:255,107,374...255,114,637
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Nfkbia
NFKB inhibitor alpha
increases degradation multiple interactions increases phosphorylation increases expression decreases expression
ISO
deoxynivalenol results in increased degradation of NFKBIA protein deoxynivalenol inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of NFKBIA protein] deoxynivalenol results in increased phosphorylation of NFKBIA protein deoxynivalenol results in increased expression of NFKBIA mRNA deoxynivalenol results in decreased expression of NFKBIA mRNA; deoxynivalenol results in decreased expression of NFKBIA protein lipopolysaccharide, E coli O55-B5 inhibits the reaction [deoxynivalenol results in increased degradation of NFKBIA protein]
CTD
PMID:8887449 PMID:18485432 PMID:23253260 PMID:24937323 PMID:26961612 PMID:34400200 More...
NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072
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Nfkbib
NFKB inhibitor beta
increases expression
ISO
deoxynivalenol results in increased expression of NFKBIB mRNA
CTD
PMID:22846391
NCBI chr 1:93,173,817...93,181,387
Ensembl chr 1:93,173,820...93,326,366
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Nfya
nuclear transcription factor Y subunit alpha
increases expression
ISO
deoxynivalenol results in increased expression of NFYA protein
CTD
PMID:33890134
NCBI chr 9:20,085,067...20,111,521
Ensembl chr 9:20,085,073...20,111,504
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Ngdn
neuroguidin
increases expression
ISO
deoxynivalenol results in increased expression of NGDN protein
CTD
PMID:39638853
NCBI chr15:32,459,898...32,467,260
Ensembl chr15:32,399,109...32,467,260
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Nherf1
NHERF family PDZ scaffold protein 1
decreases phosphorylation
ISO
deoxynivalenol results in decreased phosphorylation of NHERF1 protein
CTD
PMID:23811945
NCBI chr10:100,902,165...100,919,265
Ensembl chr10:100,901,227...100,919,579
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Nhp2
NHP2 ribonucleoprotein
increases expression
ISO
deoxynivalenol results in increased expression of NHP2 protein
CTD
PMID:39638853
NCBI chr10:36,378,020...36,381,362
Ensembl chr10:36,377,997...36,381,354
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Niban3
niban apoptosis regulator 3
affects phosphorylation
ISO
deoxynivalenol affects the phosphorylation of NIBAN3 protein
CTD
PMID:23811945
NCBI chr16:18,341,108...18,352,571
Ensembl chr16:18,341,141...18,352,575
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Nid1
nidogen 1
decreases expression
ISO
deoxynivalenol results in decreased expression of NID1 protein
CTD
PMID:39638853
NCBI chr17:93,069,013...93,142,416
Ensembl chr17:93,069,278...93,142,386
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Nifk
nucleolar protein interacting with the FHA domain of MKI67
increases expression
ISO
deoxynivalenol results in increased expression of NIFK protein
CTD
PMID:39638853
NCBI chr13:31,946,119...31,955,950
Ensembl chr13:31,946,108...31,959,561
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Nipbl
NIPBL, cohesin loading factor
increases phosphorylation
ISO
deoxynivalenol results in increased phosphorylation of NIPBL protein
CTD
PMID:23811945
NCBI chr 2:59,126,676...59,314,841
Ensembl chr 2:59,126,676...59,293,277
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Nkrf
NFKB repressing factor
increases expression
ISO
deoxynivalenol results in increased expression of NKRF protein
CTD
PMID:39638853
NCBI chr X:120,992,038...121,010,251
Ensembl chr X:120,992,038...121,010,251
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Nle1
notchless homolog 1
increases expression
ISO
deoxynivalenol results in increased expression of NLE1 protein
CTD
PMID:39638853
NCBI chr10:68,331,609...68,342,562
Ensembl chr10:68,331,609...68,340,386
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Nln
neurolysin
increases expression
ISO
deoxynivalenol results in increased expression of NLN protein
CTD
PMID:39638853
NCBI chr 2:36,867,436...36,966,749
Ensembl chr 2:36,853,551...36,966,680
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Nlrp3
NLR family, pyrin domain containing 3
multiple interactions increases expression
ISO
deoxynivalenol promotes the reaction [fumonisin B1 results in increased expression of NLRP3 mRNA]; deoxynivalenol promotes the reaction [fumonisin B1 results in increased expression of NLRP3 protein]; fumonisin B1 promotes the reaction [deoxynivalenol results in increased expression of NLRP3 mRNA]; fumonisin B1 promotes the reaction [deoxynivalenol results in increased expression of NLRP3 protein] deoxynivalenol results in increased expression of NLRP3 mRNA; deoxynivalenol results in increased expression of NLRP3 protein
CTD
PMID:36309173
NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,828,014...44,853,394
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Nnmt
nicotinamide N-methyltransferase
multiple interactions increases expression
ISO
NNMT protein promotes the reaction [deoxynivalenol results in decreased expression of GCLC protein]; NNMT protein promotes the reaction [deoxynivalenol results in decreased expression of GPX4 protein]; NNMT protein promotes the reaction [deoxynivalenol results in decreased expression of NQO1 protein]; NNMT protein promotes the reaction [deoxynivalenol results in decreased expression of SLC7A11 protein] deoxynivalenol results in increased expression of NNMT mRNA; deoxynivalenol results in increased expression of NNMT protein
CTD
PMID:39983889
NCBI chr 8:57,820,156...57,851,301
Ensembl chr 8:57,825,464...57,843,174
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Noc2l
NOC2-like nucleolar associated transcriptional repressor
increases expression
ISO
deoxynivalenol results in increased expression of NOC2L protein
CTD
PMID:39638853
NCBI chr 5:172,102,369...172,114,168
Ensembl chr 5:172,101,223...172,114,162
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Noc3l
NOC3-like DNA replication regulator
increases expression
ISO
deoxynivalenol results in increased expression of NOC3L protein
CTD
PMID:39638853
NCBI chr 1:245,969,179...245,997,761
Ensembl chr 1:245,969,179...245,997,708
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Nod2
nucleotide-binding oligomerization domain containing 2
multiple interactions
ISO
[[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which affects the localization of ELAVL1 protein] which co-treated with deoxynivalenol] promotes the reaction [[ELAVL1 protein binds to ATF3 3' UTR] which results in increased stability of ATF3 mRNA]; [[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] affects the localization of ELAVL1 protein; [[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] affects the phosphorylation of RELA protein; [[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of ATF3 mRNA; [[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of CXCL1 mRNA; [[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of CXCL8 mRNA; [Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] promotes the reaction [deoxynivalenol results in increased expression of ATF3 mRNA]; [Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] promotes the reaction [deoxynivalenol results in increased expression of CXCL1 mRNA]; [Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] promotes the reaction [deoxynivalenol results in increased expression of CXCL8 mRNA]; ATF3 protein affects the reaction [[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] affects the phosphorylation of RELA protein]; ELAVL1 protein affects the reaction [[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of CXCL1 mRNA]; ELAVL1 protein affects the reaction [[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of CXCL8 mRNA]
CTD
PMID:22003189
NCBI chr19:34,555,832...34,596,281
Ensembl chr19:34,555,832...34,722,846
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Nol10
nucleolar protein 10
increases expression
ISO
deoxynivalenol results in increased expression of NOL10 protein
CTD
PMID:39638853
NCBI chr 6:45,861,773...45,954,067
Ensembl chr 6:45,872,960...45,954,066
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Nol11
nucleolar protein 11
increases expression
ISO
deoxynivalenol results in increased expression of NOL11 protein
CTD
PMID:39638853
NCBI chr10:92,621,482...92,641,394
Ensembl chr10:92,621,498...92,641,394
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Nol7
nucleolar protein 7
increases expression
ISO
deoxynivalenol results in increased expression of NOL7 protein
CTD
PMID:39638853
NCBI chr17:21,509,605...21,512,879
Ensembl chr17:21,509,605...21,513,196
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Nolc1
nucleolar and coiled-body phosphoprotein 1
increases expression
ISO
deoxynivalenol results in increased expression of NOLC1 mRNA; deoxynivalenol results in increased expression of NOLC1 protein
CTD
PMID:24247028 PMID:39638853
NCBI chr 1:254,870,195...254,881,070
Ensembl chr 1:254,870,319...254,881,069
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Nono
non-POU domain containing, octamer-binding
increases expression
ISO
deoxynivalenol results in increased expression of NONO protein
CTD
PMID:39638853
NCBI chr X:70,594,116...70,611,976
Ensembl chr X:70,593,888...70,611,979
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Nop14
NOP14 nucleolar protein
increases expression
ISO
deoxynivalenol results in increased expression of NOP14 protein
CTD
PMID:39638853
NCBI chr14:80,305,912...80,327,053
Ensembl chr14:80,305,338...80,328,655
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Nop16
NOP16 nucleolar protein
increases expression
ISO
deoxynivalenol results in increased expression of NOP16 protein
CTD
PMID:39638853
NCBI chr17:10,028,058...10,032,975
Ensembl chr17:10,028,034...10,033,038
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Nop2
NOP2 nucleolar protein
increases expression
ISO
deoxynivalenol results in increased expression of NOP2 protein
CTD
PMID:39638853
NCBI chr 4:159,618,894...159,630,697
Ensembl chr 4:159,618,966...159,630,697
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Nop56
NOP56 ribonucleoprotein
affects phosphorylation increases expression increases phosphorylation
ISO
deoxynivalenol affects the phosphorylation of NOP56 protein deoxynivalenol results in increased expression of NOP56 protein deoxynivalenol results in increased phosphorylation of NOP56 protein
CTD
PMID:23352502 PMID:23811945 PMID:39638853
NCBI chr 3:137,926,187...137,934,971
Ensembl chr 3:137,929,646...137,934,959
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Nop58
NOP58 ribonucleoprotein
increases expression
ISO
deoxynivalenol results in increased expression of NOP58 protein
CTD
PMID:39638853
NCBI chr 9:68,614,992...68,638,911
Ensembl chr 9:68,615,010...68,638,909
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Nos2
nitric oxide synthase 2
multiple interactions increases activity increases expression
ISO EXP
Celecoxib inhibits the reaction [deoxynivalenol results in increased expression of NOS2 protein]; deoxynivalenol inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 mRNA]; deoxynivalenol inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 protein]; Ro 31-8220 inhibits the reaction [deoxynivalenol results in increased expression of NOS2 protein] deoxynivalenol inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] deoxynivalenol results in increased activity of NOS2 protein deoxynivalenol results in increased expression of NOS2 mRNA 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; Adenine inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]; deoxynivalenol results in increased ubiquitination of and results in increased degradation of NOS2 protein; lactacystin inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; lactacystin inhibits the reaction [deoxynivalenol results in increased degradation of NOS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; SB 203580 inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]
CTD
PMID:19857559 PMID:21748807 PMID:24937323 PMID:25766886 PMID:32416088 PMID:34673182 More...
NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
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Npffr2
neuropeptide FF receptor 2
increases expression
ISO
deoxynivalenol results in increased expression of NPFFR2 mRNA
CTD
PMID:23792671
NCBI chr14:18,794,868...18,842,186
Ensembl chr14:18,797,234...18,842,186
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Npm1
nucleophosmin 1
increases phosphorylation increases expression
ISO
deoxynivalenol results in increased phosphorylation of NPM1 protein deoxynivalenol results in increased expression of NPM1 protein
CTD
PMID:23811945 PMID:39638853
NCBI chr10:18,245,739...18,255,913
Ensembl chr10:18,245,740...18,256,024 Ensembl chr X:18,245,740...18,256,024
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Npm3
nucleophosmin/nucleoplasmin, 3
increases expression
ISO
deoxynivalenol results in increased expression of NPM3 protein
CTD
PMID:39638853
NCBI chr 1:254,544,664...254,546,649
Ensembl chr 1:254,544,664...254,546,649
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Npy
neuropeptide Y
increases expression
EXP
deoxynivalenol results in increased expression of NPY mRNA
CTD
PMID:32738333
NCBI chr 4:80,212,111...80,219,310
Ensembl chr 4:80,212,111...80,219,310
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Nqo1
NAD(P)H quinone dehydrogenase 1
increases expression decreases expression multiple interactions
ISO
deoxynivalenol results in increased expression of NQO1 mRNA deoxynivalenol results in decreased expression of NQO1 mRNA; deoxynivalenol results in decreased expression of NQO1 protein NNMT protein promotes the reaction [deoxynivalenol results in decreased expression of NQO1 protein]; Resveratrol inhibits the reaction [deoxynivalenol results in decreased expression of NQO1 protein]
CTD
PMID:34400200 PMID:37419272 PMID:39147090 PMID:39983889
NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260
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Nr1d1
nuclear receptor subfamily 1, group D, member 1
increases expression multiple interactions decreases expression
ISO
deoxynivalenol results in increased expression of NR1D1 mRNA BMAL1 protein promotes the reaction [deoxynivalenol results in decreased expression of NR1D1 protein]; deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of NR1D1 mRNA]
CTD
PMID:22846391 PMID:36602574
NCBI chr10:84,224,599...84,231,812
Ensembl chr10:84,224,540...84,231,812
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Nr1d2
nuclear receptor subfamily 1, group D, member 2
multiple interactions
ISO
deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of NR1D2 mRNA]
CTD
PMID:36602574
NCBI chr15:9,955,034...9,981,329
Ensembl chr15:9,954,906...9,981,330
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Nr4a1
nuclear receptor subfamily 4, group A, member 1
increases expression multiple interactions
ISO
deoxynivalenol results in increased expression of NR4A1 mRNA [Colforsin co-treated with deoxynivalenol] results in increased expression of NR4A1 mRNA
CTD
PMID:15371230 PMID:26783879
NCBI chr 7:134,247,153...134,268,044
Ensembl chr 7:134,247,192...134,268,041
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Nr4a3
nuclear receptor subfamily 4, group A, member 3
increases expression
ISO
deoxynivalenol results in increased expression of NR4A3 mRNA
CTD
PMID:26763390
NCBI chr 5:67,157,141...67,198,287
Ensembl chr 5:67,157,375...67,198,285
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Nr5a1
nuclear receptor subfamily 5, group A, member 1
decreases expression
ISO
deoxynivalenol results in decreased expression of NR5A1 mRNA
CTD
PMID:22982764
NCBI chr 3:42,874,505...42,896,109
Ensembl chr 3:42,875,221...42,896,046
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Nrros
negative regulator of reactive oxygen species
affects phosphorylation
ISO
deoxynivalenol affects the phosphorylation of NRROS protein
CTD
PMID:23811945
NCBI chr11:82,133,608...82,151,160
Ensembl chr11:82,133,144...82,151,308
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Nsa2
NSA2 ribosome biogenesis factor
increases expression
ISO
deoxynivalenol results in increased expression of NSA2 protein
CTD
PMID:39638853
NCBI chr 2:30,177,753...30,184,004
Ensembl chr 2:30,177,702...30,184,031
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Nsdhl
NAD(P) dependent 3-beta-hydroxysteroid dehydrogenase NSDHL
decreases expression
ISO
deoxynivalenol results in decreased expression of NSDHL protein
CTD
PMID:39638853
NCBI chr X:155,817,301...155,848,224
Ensembl chr X:155,817,340...155,848,220
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Nsun5
NOP2/Sun RNA methyltransferase 5
increases expression
ISO
deoxynivalenol results in increased expression of NSUN5 protein
CTD
PMID:39638853
NCBI chr12:26,930,204...26,935,887
Ensembl chr12:26,930,863...26,936,130
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Nt5e
5' nucleotidase, ecto
decreases expression
ISO
deoxynivalenol results in decreased expression of NT5E protein
CTD
PMID:39638853
NCBI chr 8:98,150,925...98,195,646
Ensembl chr 8:98,150,900...98,195,645
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Ntrk2
neurotrophic receptor tyrosine kinase 2
decreases expression
ISO
deoxynivalenol results in decreased expression of NTRK2 mRNA
CTD
PMID:31863870
NCBI chr17:5,560,558...5,875,899
Ensembl chr17:5,564,570...5,874,628
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Nucks1
nuclear casein kinase and cyclin-dependent kinase substrate 1
decreases phosphorylation affects phosphorylation
ISO
deoxynivalenol results in decreased phosphorylation of NUCKS1 protein deoxynivalenol affects the phosphorylation of NUCKS1 protein
CTD
PMID:23352502 PMID:23811945
NCBI chr13:45,897,275...45,926,491
Ensembl chr13:45,897,248...45,923,101
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Nudc
nuclear distribution C, dynein complex regulator
increases expression
ISO
deoxynivalenol results in increased expression of NUDC protein
CTD
PMID:39638853
NCBI chr 5:151,041,878...151,055,260
Ensembl chr 5:151,041,875...151,055,260
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Nudcd1
NudC domain containing 1
increases expression
ISO
deoxynivalenol results in increased expression of NUDCD1 mRNA
CTD
PMID:23792671
NCBI chr 7:77,436,035...77,480,651
Ensembl chr 7:77,436,036...77,480,575
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Nudt16l1
nudix hydrolase 16 like 1
decreases expression
ISO
deoxynivalenol results in decreased expression of NUDT16L1 protein
CTD
PMID:39638853
NCBI chr10:11,142,626...11,144,542
Ensembl chr10:11,142,627...11,144,764
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Nufip1
nuclear FMR1 interacting protein 1
increases expression
ISO
deoxynivalenol results in increased expression of NUFIP1 mRNA
CTD
PMID:31863870
NCBI chr15:57,838,864...57,869,597
Ensembl chr15:57,837,608...57,869,594
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Nufip2
nuclear FMR1 interacting protein 2
increases expression
ISO
deoxynivalenol results in increased expression of NUFIP2 protein
CTD
PMID:39638853
NCBI chr10:63,072,964...63,105,823
Ensembl chr10:63,073,397...63,105,823
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Numa1
nuclear mitotic apparatus protein 1
affects phosphorylation
ISO
deoxynivalenol affects the phosphorylation of NUMA1 protein
CTD
PMID:23352502
NCBI chr 1:165,709,893...165,784,848
Ensembl chr 1:165,709,905...165,784,848
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Nup107
nucleoporin 107
increases expression
ISO
deoxynivalenol results in increased expression of NUP107 protein
CTD
PMID:39638853
NCBI chr 7:55,239,610...55,285,050
Ensembl chr 7:55,239,613...55,285,234
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Nup155
nucleoporin 155
decreases phosphorylation
ISO
deoxynivalenol results in decreased phosphorylation of NUP155 protein
CTD
PMID:23811945
NCBI chr 2:58,927,171...58,980,162
Ensembl chr 2:58,928,537...58,981,242
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Nup214
nucleoporin 214
increases expression
ISO
deoxynivalenol results in increased expression of NUP214 protein
CTD
PMID:39638853
NCBI chr 3:35,652,841...35,738,323
Ensembl chr 3:35,652,858...35,739,192
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Nup35
nucleoporin 35
increases expression
ISO
deoxynivalenol results in increased expression of NUP35 protein
CTD
PMID:39638853
NCBI chr 3:85,965,907...85,991,659
Ensembl chr 3:85,945,080...85,992,027
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Nup98
nucleoporin 98 and 96 precursor
affects phosphorylation increases expression increases phosphorylation
ISO
deoxynivalenol affects the phosphorylation of NUP98 protein deoxynivalenol results in increased expression of NUP98 protein deoxynivalenol results in increased phosphorylation of NUP98 protein
CTD
PMID:23811945 PMID:39638853
NCBI chr 1:165,906,405...166,003,366
Ensembl chr 1:165,906,405...166,003,366
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Nusap1
nucleolar and spindle associated protein 1
increases expression
ISO
deoxynivalenol results in increased expression of NUSAP1 mRNA
CTD
PMID:31863870
NCBI chr 3:127,057,220...127,092,779
Ensembl chr 3:127,057,265...127,087,237
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Oas2
2'-5' oligoadenylate synthetase 2
decreases expression
ISO
deoxynivalenol results in decreased expression of OAS2 mRNA
CTD
PMID:17090620
NCBI chr12:41,464,568...41,492,036
Ensembl chr12:41,467,315...41,495,881
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Oat
ornithine aminotransferase
decreases expression
ISO
deoxynivalenol results in decreased expression of OAT protein
CTD
PMID:39638853
NCBI chr 1:196,777,973...196,797,754
Ensembl chr 1:196,777,975...196,797,754
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Ocln
occludin
affects localization decreases expression multiple interactions increases expression
ISO
deoxynivalenol affects the localization of OCLN protein deoxynivalenol results in decreased expression of OCLN mRNA; deoxynivalenol results in decreased expression of OCLN protein 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide promotes the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of OCLN mRNA]]; 6-formylindolo(3,2-b)carbazole inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of OCLN mRNA]]; Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of OCLN mRNA]; Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of OCLN protein]; lauric acid inhibits the reaction [deoxynivalenol results in decreased expression of OCLN protein]; sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of OCLN mRNA] deoxynivalenol results in increased expression of OCLN mRNA
CTD
PMID:20362602 PMID:24568843 PMID:34506767 PMID:35381244 PMID:35817260
NCBI chr 2:33,391,303...33,442,207
Ensembl chr 2:33,391,303...33,430,411
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Odc1
ornithine decarboxylase 1
increases activity
ISO
deoxynivalenol results in increased activity of ODC1 protein
CTD
PMID:24937323
NCBI chr 6:46,058,439...46,065,148
Ensembl chr 6:46,058,463...46,065,146
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Oga
O-GlcNAcase
increases expression
ISO
deoxynivalenol results in increased expression of OGA mRNA
CTD
PMID:31863870
NCBI chr 1:254,547,311...254,589,596
Ensembl chr 1:254,547,311...254,582,855
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Ogg1
8-oxoguanine DNA glycosylase
increases expression
ISO
deoxynivalenol results in increased expression of OGG1 mRNA; deoxynivalenol results in increased expression of OGG1 protein
CTD
PMID:24355168
NCBI chr 4:148,030,237...148,037,599
Ensembl chr 4:148,030,349...148,037,604
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Oip5
Opa interacting protein 5
increases expression
ISO
deoxynivalenol results in increased expression of OIP5 mRNA
CTD
PMID:31863870
NCBI chr 3:127,047,559...127,057,043
Ensembl chr 3:127,047,559...127,057,043
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Os9
OS9, endoplasmic reticulum lectin
decreases expression
ISO
deoxynivalenol results in decreased expression of OS9 protein
CTD
PMID:39638853
NCBI chr 7:64,802,517...64,829,185
Ensembl chr 7:64,802,103...64,829,070
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Oser1
oxidative stress responsive serine-rich 1
increases expression
ISO
deoxynivalenol results in increased expression of OSER1 mRNA
CTD
PMID:31863870
NCBI chr 3:172,486,417...172,504,607
Ensembl chr 3:172,486,440...172,504,597
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Ostf1
osteoclast stimulating factor 1
increases phosphorylation
ISO
deoxynivalenol results in increased phosphorylation of OSTF1 protein
CTD
PMID:23811945
NCBI chr 1:225,428,661...225,475,851
Ensembl chr 1:225,428,661...225,541,027
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P4ha3
prolyl 4-hydroxylase subunit alpha 3
decreases expression
ISO
deoxynivalenol results in decreased expression of P4HA3 mRNA
CTD
PMID:31863870
NCBI chr 1:164,040,852...164,075,922
Ensembl chr 1:164,040,864...164,076,435
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Pa2g4
proliferation-associated 2G4
increases expression
ISO
deoxynivalenol results in increased expression of PA2G4 protein
CTD
PMID:39638853
NCBI chr 7:1,569,326...1,576,794
Ensembl chr 7:1,569,327...1,576,802
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Pabpc1
poly(A) binding protein, cytoplasmic 1
increases expression
ISO
deoxynivalenol results in increased expression of PABPC1 protein
CTD
PMID:39638853
NCBI chr 7:69,662,513...69,674,806
Ensembl chr 7:69,663,068...69,675,050
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Paf1
PAF1 homolog, Paf1/RNA polymerase II complex component
increases expression
ISO
deoxynivalenol results in increased expression of PAF1 protein
CTD
PMID:39638853
NCBI chr 1:92,811,197...92,816,775
Ensembl chr 1:92,798,237...92,816,779
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Pah
phenylalanine hydroxylase
decreases expression
ISO
deoxynivalenol results in decreased expression of PAH protein
CTD
PMID:39638853
NCBI chr 7:23,793,096...23,885,631
Ensembl chr 7:23,792,781...23,885,627
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Pak1ip1
PAK1 interacting protein 1
increases expression
ISO
deoxynivalenol results in increased expression of PAK1IP1 protein
CTD
PMID:39638853
NCBI chr17:23,947,978...23,959,055
Ensembl chr17:23,939,509...23,959,055
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Palld
palladin, cytoskeletal associated protein
affects phosphorylation
ISO
deoxynivalenol affects the phosphorylation of PALLD protein
CTD
PMID:23811945
NCBI chr16:33,238,943...33,632,236
Ensembl chr16:33,238,956...33,632,232
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Pam16
presequence translocase associated motor 16
increases expression
ISO
deoxynivalenol results in increased expression of PAM16 protein
CTD
PMID:39638853
NCBI chr10:11,449,316...11,457,071
Ensembl chr10:11,449,117...11,460,526
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Parp1
poly (ADP-ribose) polymerase 1
increases cleavage multiple interactions increases expression
ISO
deoxynivalenol results in increased cleavage of PARP1 protein benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone affects the reaction [deoxynivalenol affects the expression of and results in increased cleavage of PARP1 protein]; deoxynivalenol affects the expression of and results in increased cleavage of PARP1 protein benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [deoxynivalenol results in decreased expression of and results in increased cleavage of PARP1 protein]; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [deoxynivalenol results in decreased expression of and results in increased cleavage of PARP1 protein]; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased cleavage of PARP1 protein]; deoxynivalenol results in decreased expression of and results in increased cleavage of PARP1 protein; GSDME protein inhibits the reaction [deoxynivalenol results in increased cleavage of PARP1 protein] deoxynivalenol results in increased expression of PARP1 mRNA
CTD
PMID:19410639 PMID:34677630 PMID:35925383
NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567
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Pbxip1
PBX homeobox interacting protein 1
decreases expression
ISO
deoxynivalenol results in decreased expression of PBXIP1 protein
CTD
PMID:39638853
NCBI chr 2:177,154,056...177,167,810
Ensembl chr 2:177,154,101...177,167,328
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Pck2
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
decreases expression
ISO
deoxynivalenol results in decreased expression of PCK2 mRNA
CTD
PMID:31863870
NCBI chr15:32,997,853...33,006,691
Ensembl chr15:32,997,834...33,016,864
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Pcna
proliferating cell nuclear antigen
multiple interactions decreases expression
ISO
lauric acid inhibits the reaction [deoxynivalenol results in decreased expression of PCNA protein]
CTD
PMID:34506767
NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901
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Pcolce
procollagen C-endopeptidase enhancer
decreases expression
ISO
deoxynivalenol results in decreased expression of PCOLCE mRNA
CTD
PMID:31863870
NCBI chr12:24,720,972...24,727,287
Ensembl chr12:24,720,936...24,727,287
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Pcyox1l
prenylcysteine oxidase 1 like
decreases expression
ISO
deoxynivalenol results in decreased expression of PCYOX1L mRNA
CTD
PMID:31863870
NCBI chr18:57,420,971...57,431,632
Ensembl chr18:57,420,977...57,431,632
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Pdcd1
programmed cell death 1
increases expression
ISO
deoxynivalenol results in increased expression of PDCD1 mRNA
CTD
PMID:27757495
NCBI chr 9:101,866,124...101,879,278
Ensembl chr 9:101,866,126...101,879,270
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Pdcd11
programmed cell death 11
affects phosphorylation
ISO
deoxynivalenol affects the phosphorylation of PDCD11 protein
CTD
PMID:23352502
NCBI chr 1:255,922,198...255,963,336
Ensembl chr 1:255,922,225...255,963,336
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Pdcd4
programmed cell death 4
decreases expression
ISO
deoxynivalenol results in decreased expression of PDCD4 protein
CTD
PMID:39638853
NCBI chr 1:262,912,659...262,949,581
Ensembl chr 1:262,926,656...262,950,189
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Pdcd5
programmed cell death 5
increases expression
ISO
deoxynivalenol results in increased expression of PDCD5 protein
CTD
PMID:39638853
NCBI chr 1:97,442,755...97,448,084
Ensembl chr 1:97,442,755...97,449,844
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Pdcd6
programmed cell death 6
increases expression
ISO
deoxynivalenol results in increased expression of PDCD6 protein
CTD
PMID:39638853
NCBI chr 1:30,795,105...30,810,771
Ensembl chr 1:30,795,040...30,810,773
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Pde12
phosphodiesterase 12
increases expression
ISO
deoxynivalenol results in increased expression of PDE12 mRNA; deoxynivalenol results in increased expression of PDE12 protein
CTD
PMID:31863870 PMID:39638853
NCBI chr16:1,926,807...1,932,383
Ensembl chr16:1,922,131...1,932,611
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Pdlim2
PDZ and LIM domain 2
affects phosphorylation increases phosphorylation
ISO
deoxynivalenol affects the phosphorylation of PDLIM2 protein deoxynivalenol results in increased phosphorylation of PDLIM2 protein
CTD
PMID:23352502 PMID:23811945
NCBI chr15:51,647,195...51,659,904
Ensembl chr15:51,647,197...51,658,958
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Pdlim4
PDZ and LIM domain 4
affects phosphorylation
ISO
deoxynivalenol affects the phosphorylation of PDLIM4 protein
CTD
PMID:23811945
NCBI chr10:38,699,444...38,713,696
Ensembl chr10:38,699,444...38,713,659
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Pdpr
pyruvate dehydrogenase phosphatase regulatory subunit
decreases expression
ISO
deoxynivalenol results in decreased expression of PDPR protein
CTD
PMID:39638853
NCBI chr19:55,974,611...56,019,045
Ensembl chr19:55,974,550...56,019,044
G
Pdss2
decaprenyl diphosphate synthase subunit 2
increases expression
ISO
deoxynivalenol results in increased expression of PDSS2 mRNA
CTD
PMID:31863870
NCBI chr20:48,291,788...48,520,846
Ensembl chr20:48,291,797...48,535,689
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Pdzk1
PDZ domain containing 1
decreases expression
ISO
deoxynivalenol results in decreased expression of PDZK1 protein
CTD
PMID:39638853
NCBI chr 2:187,064,995...187,096,348
Ensembl chr 2:187,065,013...187,096,806
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Pea15
proliferation and apoptosis adaptor protein 15
affects phosphorylation
ISO
deoxynivalenol affects the phosphorylation of PEA15A protein
CTD
PMID:23811945
NCBI chr13:87,190,189...87,199,811
Ensembl chr13:87,187,295...87,199,859
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Peg10
paternally expressed 10
decreases expression
ISO
deoxynivalenol results in decreased expression of PEG10 protein
CTD
PMID:39638853
NCBI chr 4:33,809,026...33,822,224
Ensembl chr 4:33,817,190...33,819,166 Ensembl chr 4:33,817,190...33,819,166
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Pepd
peptidase D
decreases expression
ISO
deoxynivalenol results in decreased expression of PEPD protein
CTD
PMID:39638853
NCBI chr 1:96,673,624...96,818,197
Ensembl chr 1:96,673,607...96,818,190
G
Per1
period circadian regulator 1
multiple interactions
ISO
deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of PER1 mRNA]; deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of PER1 protein]
CTD
PMID:36602574
NCBI chr10:54,299,002...54,313,804
Ensembl chr10:54,302,641...54,314,211
G
Per2
period circadian regulator 2
multiple interactions decreases expression
ISO
BMAL1 protein promotes the reaction [deoxynivalenol results in decreased expression of PER2 protein] deoxynivalenol results in decreased expression of PER2 mRNA; deoxynivalenol results in decreased expression of PER2 protein
CTD
PMID:36602574
NCBI chr 9:99,454,828...99,497,069
Ensembl chr 9:99,454,830...99,496,993
G
Per3
period circadian regulator 3
multiple interactions decreases expression
ISO
BMAL1 protein promotes the reaction [deoxynivalenol results in decreased expression of PER3 protein]; deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of PER3 mRNA]
CTD
PMID:36602574
NCBI chr 5:166,740,914...166,778,243
Ensembl chr 5:166,743,050...166,777,999
G
Pes1
pescadillo ribosomal biogenesis factor 1
increases expression
ISO
deoxynivalenol results in increased expression of PES1 protein
CTD
PMID:39638853
NCBI chr14:83,074,346...83,090,726
Ensembl chr14:83,074,319...83,091,718
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Pfkl
phosphofructokinase, liver type
decreases expression
ISO
deoxynivalenol results in decreased expression of PFKL protein
CTD
PMID:39638853
NCBI chr20:10,663,907...10,685,967
Ensembl chr20:10,663,955...10,685,966
G
Pgm1
phosphoglucomutase 1
decreases expression
ISO
deoxynivalenol results in decreased expression of PGM1 protein
CTD
PMID:39638853
NCBI chr 5:119,710,734...119,770,159
Ensembl chr 5:119,710,737...119,770,159
G
Pgr
progesterone receptor
multiple interactions increases expression
ISO
afimoxifene inhibits the reaction [deoxynivalenol results in increased expression of PGR mRNA]; deoxynivalenol promotes the reaction [Estradiol results in increased expression of PGR mRNA]; deoxynivalenol promotes the reaction [Zearalenone results in increased expression of PGR mRNA]; ESR1 promotes the reaction [deoxynivalenol results in increased expression of PGR mRNA]
CTD
PMID:35588983
NCBI chr 8:14,354,398...14,413,271
Ensembl chr 8:14,354,398...14,413,271
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Pgrmc1
progesterone receptor membrane component 1
affects phosphorylation
ISO
deoxynivalenol affects the phosphorylation of PGRMC1 protein
CTD
PMID:23811945
NCBI chr X:120,698,610...120,706,805
Ensembl chr X:120,698,610...120,706,805
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Phax
phosphorylated adaptor for RNA export
increases expression
ISO
deoxynivalenol results in increased expression of PHAX mRNA
CTD
PMID:31863870
NCBI chr18:52,251,231...52,267,916
Ensembl chr18:52,248,709...52,267,915
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Phgdh
phosphoglycerate dehydrogenase
decreases expression
ISO
deoxynivalenol results in decreased expression of PHGDH mRNA; deoxynivalenol results in decreased expression of PHGDH protein
CTD
PMID:31863870 PMID:39638853
NCBI chr 2:188,595,700...188,624,789
Ensembl chr 2:188,595,700...188,624,789
G
Phlda1
pleckstrin homology-like domain, family A, member 1
increases expression
ISO
deoxynivalenol results in increased expression of PHLDA1 mRNA
CTD
PMID:31863870
NCBI chr 7:48,853,690...48,855,894
Ensembl chr 7:48,853,260...48,857,542
G
Phlda3
pleckstrin homology-like domain, family A, member 3
increases expression
ISO
deoxynivalenol results in increased expression of PHLDA3 mRNA
CTD
PMID:31863870
NCBI chr13:49,745,003...49,748,088
Ensembl chr13:49,742,591...49,749,621
G
Pi4kb
phosphatidylinositol 4-kinase beta
affects phosphorylation
ISO
deoxynivalenol affects the phosphorylation of PI4KB protein
CTD
PMID:23811945
NCBI chr 2:185,229,392...185,261,697
Ensembl chr 2:185,228,799...185,261,693
G
Pik3cg
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
affects phosphorylation
ISO
deoxynivalenol affects the phosphorylation of PIK3CG protein
CTD
PMID:23811945
NCBI chr 6:54,494,247...54,529,563
Ensembl chr 6:54,478,603...54,529,509
G
Pklr
pyruvate kinase L/R
decreases expression
ISO
deoxynivalenol results in decreased expression of PKLR protein
CTD
PMID:39638853
NCBI chr 2:176,840,779...176,849,637
Ensembl chr 2:176,840,764...176,849,644
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Pkm
pyruvate kinase M1/2
decreases expression
ISO
deoxynivalenol results in decreased expression of PKM protein
CTD
PMID:39638853
NCBI chr 8:68,949,731...68,975,394
Ensembl chr 8:68,948,815...68,975,396
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Pkp3
plakophilin 3
increases expression
ISO
deoxynivalenol results in increased expression of PKP3 protein
CTD
PMID:39638853
NCBI chr 1:205,617,511...205,628,441
Ensembl chr 1:205,617,511...205,628,440
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Plec
plectin
affects phosphorylation decreases phosphorylation
ISO
deoxynivalenol affects the phosphorylation of PLEC protein deoxynivalenol results in decreased phosphorylation of PLEC protein
CTD
PMID:23352502 PMID:23811945
NCBI chr 7:109,768,447...109,829,798
Ensembl chr 7:109,768,447...109,828,089
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Plekha6
pleckstrin homology domain containing A6
affects phosphorylation
ISO
deoxynivalenol affects the phosphorylation of PLEKHA6 protein
CTD
PMID:23811945
NCBI chr13:47,166,899...47,307,003
Ensembl chr13:47,167,160...47,307,003
G
Plekho2
pleckstrin homology domain containing O2
affects phosphorylation
ISO
deoxynivalenol affects the phosphorylation of PLEKHO2 protein
CTD
PMID:23811945
NCBI chr 8:74,973,578...75,000,532
Ensembl chr 8:74,974,740...75,000,430
G
Plgrkt
plasminogen receptor with a C-terminal lysine
multiple interactions
ISO
[Selenomethionine co-treated with deoxynivalenol] results in increased expression of PLGRKT mRNA
CTD
PMID:38040082
NCBI chr 1:236,512,574...236,526,858
Ensembl chr 1:236,512,580...236,524,840
G
Plin2
perilipin 2
increases expression
ISO
deoxynivalenol results in increased expression of PLIN2 mRNA; deoxynivalenol results in increased expression of PLIN2 protein
CTD
PMID:31863870 PMID:39638853
NCBI chr 5:106,202,634...106,258,748
Ensembl chr 5:106,202,634...106,258,878
G
Plod1
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
decreases expression
ISO
deoxynivalenol results in decreased expression of PLOD1 protein
CTD
PMID:39638853
NCBI chr 5:163,623,847...163,650,737
Ensembl chr 5:163,623,848...163,651,110
G
Plod2
procollagen lysine, 2-oxoglutarate 5-dioxygenase 2
decreases expression
ISO
deoxynivalenol results in decreased expression of PLOD2 protein
CTD
PMID:39638853
NCBI chr 8:101,964,318...102,047,022
Ensembl chr 8:101,964,318...102,047,022
G
Plpp3
phospholipid phosphatase 3
decreases expression
ISO
deoxynivalenol results in decreased expression of PLPP3 protein
CTD
PMID:39638853
NCBI chr 5:125,156,000...125,231,119
Ensembl chr 5:125,155,945...125,235,667
G
Plpp5
phospholipid phosphatase 5
decreases expression
ISO
deoxynivalenol results in decreased expression of PLPP5 mRNA
CTD
PMID:31863870
NCBI chr16:73,052,204...73,056,609
Ensembl chr16:73,052,204...73,056,643
G
Plrg1
pleiotropic regulator 1
increases expression
ISO
deoxynivalenol results in increased expression of PLRG1 mRNA
CTD
PMID:31863870
NCBI chr 2:170,706,188...170,722,519
Ensembl chr 2:170,706,173...170,722,573
G
Pls3
plastin 3
decreases expression
ISO
deoxynivalenol results in decreased expression of PLS3 protein
CTD
PMID:39638853
NCBI chr X:116,401,247...116,495,898
Ensembl chr X:116,401,293...116,495,893
G
Plxnb2
plexin B2
decreases expression
ISO
deoxynivalenol results in decreased expression of PLXNB2 protein
CTD
PMID:39638853
NCBI chr 7:122,111,917...122,138,201
Ensembl chr 7:122,111,917...122,127,746
G
Pmaip1
phorbol-12-myristate-13-acetate-induced protein 1
increases expression
ISO
deoxynivalenol results in increased expression of PMAIP1 mRNA
CTD
PMID:22846391 PMID:24247028
NCBI chr18:62,255,970...62,262,384
Ensembl chr18:62,255,598...62,262,382
G
Pml
PML nuclear body scaffold
decreases phosphorylation affects phosphorylation
ISO
deoxynivalenol results in decreased phosphorylation of PML protein deoxynivalenol affects the phosphorylation of PML protein
CTD
PMID:23352502 PMID:23811945
NCBI chr 8:67,523,164...67,557,801
Ensembl chr 8:67,523,164...67,576,083
G
Pnn
pinin, desmosome associated protein
increases expression
ISO
deoxynivalenol results in increased expression of PNN protein
CTD
PMID:39638853
NCBI chr 6:82,493,032...82,501,345
Ensembl chr 6:82,492,978...82,501,933
G
Pno1
partner of NOB1 homolog
increases expression
ISO
deoxynivalenol results in increased expression of PNO1 protein
CTD
PMID:39638853
NCBI chr14:95,811,335...95,819,903
Ensembl chr14:95,688,125...95,905,881
G
Podnl1
podocan-like 1
decreases expression
ISO
deoxynivalenol results in decreased expression of PODNL1 mRNA
CTD
PMID:31863870
NCBI chr19:40,932,026...40,938,760
Ensembl chr19:40,932,026...40,938,631
G
Poldip3
DNA polymerase delta interacting protein 3
increases expression
ISO
deoxynivalenol results in increased expression of POLDIP3 protein
CTD
PMID:39638853
NCBI chr 7:116,154,892...116,183,319
Ensembl chr 7:116,154,892...116,183,300
G
Polr1c
RNA polymerase I and III subunit C
increases expression
ISO
deoxynivalenol results in increased expression of POLR1C protein
CTD
PMID:39638853
NCBI chr 9:22,233,318...22,237,430
Ensembl chr 9:22,233,305...22,237,428
G
Polr1e
RNA polymerase I subunit E
increases expression
ISO
deoxynivalenol results in increased expression of POLR1E protein
CTD
PMID:39638853
NCBI chr 5:64,075,123...64,090,900
Ensembl chr 5:64,075,122...64,091,039
G
Polr1g
RNA polymerase I subunit G
increases expression
ISO
deoxynivalenol results in increased expression of POLR1G protein
CTD
PMID:39638853
NCBI chr 1:88,135,493...88,138,769
Ensembl chr 1:88,135,493...88,138,769
G
Polr2e
RNA polymerase II, I and III subunit E
increases expression
ISO
deoxynivalenol results in increased expression of POLR2E protein
CTD
PMID:39638853
NCBI chr 7:10,317,332...10,321,280
Ensembl chr 7:10,317,389...10,321,276
G
Ppan
peter pan homolog
increases expression
ISO
deoxynivalenol results in increased expression of PPAN protein
CTD
PMID:39638853
NCBI chr 8:27,700,147...27,704,127
Ensembl chr 8:27,700,152...27,704,128
G
Pparg
peroxisome proliferator-activated receptor gamma
multiple interactions decreases activity increases expression
ISO
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [deoxynivalenol results in increased expression of PPARG protein]; EGR1 protein promotes the reaction [deoxynivalenol results in increased expression of PPARG mRNA]; lipopolysaccharide, E coli O55-B5 affects the reaction [deoxynivalenol results in increased expression of PPARG mRNA]; MAPK1 protein promotes the reaction [deoxynivalenol results in increased expression of PPARG mRNA]; MAPK3 protein promotes the reaction [deoxynivalenol results in increased expression of PPARG mRNA]; PPARG protein affects the reaction [deoxynivalenol results in decreased degradation of CXCL8 mRNA]; U 0126 inhibits the reaction [deoxynivalenol results in increased expression of PPARG mRNA] [Selenomethionine co-treated with deoxynivalenol] results in increased expression of PPARG mRNA deoxynivalenol results in decreased activity of PPARG protein
CTD
PMID:18485432 PMID:27481073 PMID:38040082
NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104
G
Ppm1d
protein phosphatase, Mg2+/Mn2+ dependent, 1D
increases expression
ISO
deoxynivalenol results in increased expression of PPM1D mRNA
CTD
PMID:31863870
NCBI chr10:70,670,026...70,706,030
Ensembl chr10:70,670,020...70,706,256
G
Ppp2ca
protein phosphatase 2 catalytic subunit alpha
increases expression
ISO
deoxynivalenol results in increased expression of PPP2CA mRNA
CTD
PMID:31863870
NCBI chr10:36,856,534...36,878,789
G
Ppp3cb
protein phosphatase 3 catalytic subunit beta
increases expression multiple interactions
ISO
deoxynivalenol results in increased expression of PPP3CB mRNA Fatty Acids, Omega-3 promotes the reaction [deoxynivalenol results in increased expression of PPP3CB mRNA]
CTD
PMID:15371230 PMID:15681167
NCBI chr15:3,809,182...3,854,204
Ensembl chr15:3,809,262...3,854,203
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Prc1
protein regulator of cytokinesis 1
increases expression
ISO
deoxynivalenol results in increased expression of PRC1 mRNA
CTD
PMID:31863870
NCBI chr 1:143,659,312...143,681,019
Ensembl chr 1:143,659,481...143,681,012
G
Prdx2
peroxiredoxin 2
decreases expression
ISO
deoxynivalenol results in decreased expression of PRDX2 protein
CTD
PMID:39638853
NCBI chr19:40,085,788...40,091,083
Ensembl chr19:40,084,430...40,091,006
G
Prelp
proline and arginine rich end leucine rich repeat protein
decreases expression
ISO
deoxynivalenol results in decreased expression of PRELP mRNA
CTD
PMID:31863870
NCBI chr13:47,920,480...47,943,547
Ensembl chr13:47,922,590...47,932,324
G
Prkar1a
protein kinase cAMP-dependent type I regulatory subunit alpha
decreases phosphorylation
ISO
deoxynivalenol results in decreased phosphorylation of PRKAR1A protein
CTD
PMID:23811945
NCBI chr10:95,120,537...95,139,028
Ensembl chr10:95,120,487...95,139,025
G
Prkar2a
protein kinase cAMP-dependent type II regulatory subunit alpha
increases phosphorylation increases expression
ISO
deoxynivalenol results in increased phosphorylation of PRKAR2A protein deoxynivalenol results in increased expression of PRKAR2A protein
CTD
PMID:23352502 PMID:39638853
NCBI chr 8:118,271,608...118,337,332
Ensembl chr 8:118,274,167...118,337,330
G
Prkca
protein kinase C, alpha
multiple interactions affects localization
ISO
Celecoxib inhibits the reaction [deoxynivalenol affects the localization of PRKCA protein]; Ro 31-8220 inhibits the reaction [deoxynivalenol affects the localization of PRKCA protein]
CTD
PMID:32416088
NCBI chr10:93,388,991...93,787,617
Ensembl chr10:93,388,991...93,787,572
G
Prkce
protein kinase C, epsilon
affects localization multiple interactions
ISO
deoxynivalenol affects the localization of PRKCE protein Celecoxib inhibits the reaction [deoxynivalenol affects the localization of PRKCE protein]; Ro 31-8220 inhibits the reaction [deoxynivalenol affects the localization of PRKCE protein]
CTD
PMID:32416088
NCBI chr 6:13,718,050...14,204,931
Ensembl chr 6:13,718,050...14,204,288
G
Prkcg
protein kinase C, gamma
multiple interactions affects localization
ISO
Celecoxib inhibits the reaction [deoxynivalenol affects the localization of PRKCG protein]; Ro 31-8220 inhibits the reaction [deoxynivalenol affects the localization of PRKCG protein]
CTD
PMID:32416088
NCBI chr 1:74,748,272...74,777,611
Ensembl chr 1:74,748,272...74,774,814
G
Prkd2
protein kinase D2
affects phosphorylation
ISO
deoxynivalenol affects the phosphorylation of PRKD2 protein
CTD
PMID:23811945
NCBI chr 1:86,640,095...86,670,476
Ensembl chr 1:86,642,629...86,670,675
G
Prmt1
protein arginine methyltransferase 1
increases expression
ISO
deoxynivalenol results in increased expression of PRMT1 protein
CTD
PMID:39638853
NCBI chr 1:104,595,339...104,605,552
Ensembl chr 1:104,595,335...104,604,827
G
Pros1
protein S
decreases expression
ISO
deoxynivalenol results in decreased expression of PROS1 mRNA
CTD
PMID:31863870
NCBI chr11:13,676,310...13,757,858
Ensembl chr11:13,676,769...13,757,852
G
Prpf3
pre-mRNA processing factor 3
increases expression
ISO
deoxynivalenol results in increased expression of PRPF3 protein
CTD
PMID:39638853
NCBI chr 2:186,067,980...186,092,427
Ensembl chr 2:186,067,162...186,092,427
G
Prpf38b
pre-mRNA processing factor 38B
increases expression
ISO
deoxynivalenol results in increased expression of PRPF38B mRNA
CTD
PMID:31863870
NCBI chr 2:199,241,312...199,250,342
Ensembl chr 2:199,241,313...199,250,338
G
Prpf4
pre-mRNA splicing tri-snRNP complex factor PRPF4
increases expression
ISO
deoxynivalenol results in increased expression of PRPF4 protein
CTD
PMID:39638853
NCBI chr 5:80,875,511...80,889,501
Ensembl chr 5:80,875,498...80,889,497
G
Prpf40a
pre-mRNA processing factor 40 homolog A
increases expression
ISO
deoxynivalenol results in increased expression of PRPF40A protein
CTD
PMID:39638853
NCBI chr 3:58,036,779...58,098,996
Ensembl chr 3:58,038,042...58,099,363
G
Prpf4b
pre-mRNA processing factor 4B
increases expression
ISO
deoxynivalenol results in increased expression of PRPF4B protein
CTD
PMID:39638853
NCBI chr17:30,190,721...30,230,153
Ensembl chr17:30,193,907...30,225,420
G
Prr5l
proline rich 5 like
decreases expression
ISO
deoxynivalenol results in decreased expression of PRR5L mRNA
CTD
PMID:26763390
NCBI chr 3:108,458,107...108,628,552
Ensembl chr 3:108,458,633...108,537,763
G
Prrc2a
proline-rich coiled-coil 2A
increases expression
ISO
deoxynivalenol results in increased expression of PRRC2A protein
CTD
PMID:39638853
NCBI chr20:3,660,981...3,686,715
Ensembl chr20:3,663,400...3,678,778
G
Prxl2a
peroxiredoxin like 2A
decreases expression
ISO
deoxynivalenol results in decreased expression of PRXL2A protein
CTD
PMID:39638853
NCBI chr16:16,900,697...16,920,521
Ensembl chr16:16,900,699...16,920,561
G
Psap
prosaposin
decreases expression
ISO
deoxynivalenol results in decreased expression of PSAP protein
CTD
PMID:39638853
NCBI chr20:28,756,951...28,783,422
Ensembl chr20:28,757,181...28,783,421
G
Psat1
phosphoserine aminotransferase 1
decreases expression
ISO
deoxynivalenol results in decreased expression of PSAT1 mRNA; deoxynivalenol results in decreased expression of PSAT1 protein
CTD
PMID:31863870 PMID:39638853
NCBI chr 1:222,623,553...222,646,187
Ensembl chr 1:222,623,556...222,655,693
G
Psen1
presenilin 1
decreases expression
ISO
deoxynivalenol results in decreased expression of PSEN1 protein
CTD
PMID:39638853
NCBI chr 6:109,054,160...109,106,191
Ensembl chr 6:109,060,352...109,106,189
G
Psip1
PC4 and SRSF1 interacting protein 1
increases phosphorylation
ISO
deoxynivalenol results in increased phosphorylation of PSIP1 protein
CTD
PMID:23811945
NCBI chr 5:102,892,929...102,925,191
Ensembl chr 5:102,892,932...102,925,170
G
Psmb8
proteasome 20S subunit beta 8
decreases expression
ISO
deoxynivalenol results in decreased expression of PSMB8 mRNA
CTD
PMID:15371230
NCBI chr20:4,654,068...4,657,049
Ensembl chr20:4,654,068...4,657,031
G
Psmd12
proteasome 26S subunit, non-ATPase 12
increases expression
ISO
deoxynivalenol results in increased expression of PSMD12 mRNA
CTD
PMID:31863870
NCBI chr10:92,937,957...92,956,601
Ensembl chr10:92,901,133...92,988,964
G
Psme3
proteasome activator subunit 3
increases expression
ISO
deoxynivalenol results in increased expression of PSME3 protein
CTD
PMID:39638853
NCBI chr10:86,757,933...86,765,719
Ensembl chr10:86,757,899...86,818,033
G
Pspc1
paraspeckle component 1
increases expression
ISO
deoxynivalenol results in increased expression of PSPC1 mRNA; deoxynivalenol results in increased expression of PSPC1 protein
CTD
PMID:31863870 PMID:39638853
NCBI chr15:34,941,445...35,027,460
Ensembl chr15:34,967,477...35,026,828
G
Psph
phosphoserine phosphatase
decreases expression
ISO
deoxynivalenol results in decreased expression of PSPH protein
CTD
PMID:39638853
NCBI chr12:32,527,091...32,541,182
Ensembl chr12:32,519,269...32,541,180
G
Pstpip2
proline-serine-threonine phosphatase-interacting protein 2
increases expression
ISO
deoxynivalenol results in increased expression of PSTPIP2 mRNA
CTD
PMID:31863870
NCBI chr18:73,585,729...73,671,868
Ensembl chr18:73,585,993...73,671,871
G
Pten
phosphatase and tensin homolog
increases expression
ISO
deoxynivalenol results in increased expression of PTEN mRNA
CTD
PMID:22846391
NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:240,043,707...240,110,330
G
Ptges
prostaglandin E synthase
increases expression decreases expression
ISO
deoxynivalenol results in increased expression of PTGES mRNA deoxynivalenol results in decreased expression of PTGES mRNA
CTD
PMID:21873375 PMID:25549547
NCBI chr 3:34,575,643...34,586,987
Ensembl chr 3:34,575,639...34,586,995
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Ptgs2
prostaglandin-endoperoxide synthase 2
increases expression increases stability multiple interactions
ISO
deoxynivalenol results in increased expression of PTGS2 mRNA; deoxynivalenol results in increased expression of PTGS2 protein deoxynivalenol results in increased stability of PTGS2 mRNA 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in increased expression of PTGS2 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in increased expression of PTGS2 protein]; Celecoxib inhibits the reaction [deoxynivalenol results in increased expression of PTGS2 protein]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased expression of PTGS2 mRNA]; Indomethacin promotes the reaction [deoxynivalenol results in increased expression of PTGS2 protein]; PTGS2 protein affects the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; PTGS2 protein affects the reaction [deoxynivalenol results in increased expression of IL6 protein]; Ro 31-8220 inhibits the reaction [deoxynivalenol results in increased expression of PTGS2 protein]; SB 203580 inhibits the reaction [deoxynivalenol results in increased expression of PTGS2 mRNA]; SB 203580 inhibits the reaction [deoxynivalenol results in increased expression of PTGS2 protein]; SB 203580 inhibits the reaction [deoxynivalenol results in increased stability of PTGS2 mRNA] Lutein inhibits the reaction [deoxynivalenol results in increased expression of PTGS2 protein]; Oxaliplatin promotes the reaction [deoxynivalenol results in increased expression of PTGS2 mRNA]
CTD
PMID:11922776 PMID:12377986 PMID:12649040 PMID:14514436 PMID:15570035 PMID:20347963 PMID:20633634 PMID:21873375 PMID:24937323 PMID:27757495 PMID:32416088 PMID:37705238 PMID:39725263 More...
NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
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Ptk7
protein tyrosine kinase 7
decreases expression
ISO
deoxynivalenol results in decreased expression of PTK7 protein
CTD
PMID:39638853
NCBI chr 9:21,849,756...21,916,077
Ensembl chr 9:21,849,801...21,916,078
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Ptp4a1
protein tyrosine phosphatase 4A1
increases expression
ISO
deoxynivalenol results in increased expression of PTP4A1 protein
CTD
PMID:39638853
NCBI chr 9:40,710,250...40,718,176
Ensembl chr 9:40,710,250...40,718,176
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Ptpn1
protein tyrosine phosphatase, non-receptor type 1
increases expression
ISO
deoxynivalenol results in increased expression of PTPN1 protein
CTD
PMID:39638853
NCBI chr 3:177,056,588...177,106,424
Ensembl chr 3:177,057,659...177,106,416
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Ptpn14
protein tyrosine phosphatase, non-receptor type 14
increases phosphorylation
ISO
deoxynivalenol results in increased phosphorylation of PTPN14 protein
CTD
PMID:23811945
NCBI chr13:103,799,473...103,951,708
Ensembl chr13:103,799,494...103,951,708
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Ptpn22
protein tyrosine phosphatase, non-receptor type 22
increases expression
ISO
deoxynivalenol results in increased expression of PTPN22 mRNA
CTD
PMID:15371230
NCBI chr 2:194,055,165...194,103,209
Ensembl chr 2:194,045,746...194,103,209
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Ptprj
protein tyrosine phosphatase, receptor type, J
increases expression
ISO
deoxynivalenol results in increased expression of PTPRJ mRNA
CTD
PMID:15371230
NCBI chr 3:96,861,785...97,017,702
Ensembl chr 3:96,861,785...97,017,656
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Ptprk
protein tyrosine phosphatase, receptor type, K
decreases expression
ISO
deoxynivalenol results in decreased expression of PTPRK protein
CTD
PMID:39638853
NCBI chr 1:18,557,091...19,056,297
Ensembl chr 1:18,558,365...19,056,107
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Pum3
pumilio RNA-binding family member 3
increases expression
ISO
deoxynivalenol results in increased expression of PUM3 protein
CTD
PMID:39638853
NCBI chr 1:234,483,482...234,527,718
Ensembl chr 1:234,487,954...234,527,612
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Pus1
pseudouridine synthase 1
increases expression
ISO
deoxynivalenol results in increased expression of PUS1 protein
CTD
PMID:39638853
NCBI chr12:51,539,659...51,548,975
Ensembl chr12:51,540,212...51,548,973
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Pvr
PVR cell adhesion molecule
increases expression
ISO
deoxynivalenol results in increased expression of PVR protein
CTD
PMID:39638853
NCBI chr 1:88,689,235...88,704,641
Ensembl chr 1:88,688,981...88,704,630
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Pycard
PYD and CARD domain containing
multiple interactions
ISO
[deoxynivalenol co-treated with fumonisin B1] results in increased expression of PYCARD mRNA; [deoxynivalenol co-treated with fumonisin B1] results in increased expression of PYCARD protein
CTD
PMID:36309173
NCBI chr 1:192,032,124...192,033,419
Ensembl chr 1:192,032,124...192,033,419
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Pyy
peptide YY
increases expression multiple interactions
ISO
deoxynivalenol results in increased expression of PYY protein; deoxynivalenol results in increased expression of PYY protein alternative form [Ruthenium Red co-treated with N-(2-hydroxy-3-(2-cyano-3-chlorophenoxy)propyl)-1,1-dimethyl-2-(2-nephthyl)ethylamine] inhibits the reaction [deoxynivalenol results in increased expression of PYY protein alternative form]; N-(2-hydroxy-3-(2-cyano-3-chlorophenoxy)propyl)-1,1-dimethyl-2-(2-nephthyl)ethylamine inhibits the reaction [deoxynivalenol results in increased expression of PYY protein alternative form]; Ruthenium Red inhibits the reaction [deoxynivalenol results in increased expression of PYY protein alternative form]
CTD
PMID:22903826 PMID:26979077
NCBI chr10:87,561,347...87,562,470
Ensembl chr10:87,561,353...87,562,206
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Qprt
quinolinate phosphoribosyltransferase
decreases expression
ISO
deoxynivalenol results in decreased expression of QPRT protein
CTD
PMID:39638853
NCBI chr 1:191,148,715...191,164,006
Ensembl chr 1:191,148,713...191,194,162
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Rab18
RAB18, member RAS oncogene family
increases expression
ISO
deoxynivalenol results in increased expression of RAB18 protein
CTD
PMID:33890134 PMID:39638853
NCBI chr17:59,639,264...59,670,653
Ensembl chr17:59,639,203...59,672,806
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Rack1
receptor for activated C kinase 1
increases expression
ISO
deoxynivalenol results in increased expression of RACK1 protein
CTD
PMID:39638853
NCBI chr10:33,668,560...33,676,031
Ensembl chr10:33,670,270...33,675,948
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Rae1
ribonucleic acid export 1
increases expression
ISO
deoxynivalenol results in increased expression of RAE1 mRNA; deoxynivalenol results in increased expression of RAE1 protein
CTD
PMID:31863870 PMID:39638853
NCBI chr 3:182,197,432...182,212,381
Ensembl chr 3:182,197,459...182,213,135
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Rag1
recombination activating 1
increases expression
ISO
deoxynivalenol results in increased expression of RAG1 mRNA
CTD
PMID:38549690
NCBI chr 3:108,372,087...108,383,184
Ensembl chr 3:108,371,978...108,383,261
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Rag2
recombination activating 2
increases expression
ISO
deoxynivalenol results in increased expression of RAG2 mRNA
CTD
PMID:38549690
NCBI chr 3:108,357,399...108,367,186
Ensembl chr 3:108,357,399...108,365,253
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Raly
RALY heterogeneous nuclear ribonucleoprotein
increases expression
ISO
deoxynivalenol results in increased expression of RALY protein
CTD
PMID:33890134
NCBI chr 3:163,766,183...163,830,726
Ensembl chr 3:163,766,478...163,830,740
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Ramp1
receptor activity modifying protein 1
decreases expression
ISO
deoxynivalenol results in decreased expression of RAMP1 mRNA
CTD
PMID:31863870
NCBI chr 9:99,213,031...99,263,696
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Ranbp2
RAN binding protein 2
decreases phosphorylation
ISO
deoxynivalenol results in decreased phosphorylation of RANBP2 protein
CTD
PMID:23352502
NCBI chr20:26,984,520...27,036,573
Ensembl chr20:26,985,275...27,036,571
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Raver1
ribonucleoprotein, PTB-binding 1
increases phosphorylation
ISO
deoxynivalenol results in increased phosphorylation of RAVER1 protein
CTD
PMID:23352502
NCBI chr 8:27,886,641...27,907,192
Ensembl chr 8:27,886,651...27,905,331
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Rbbp5
RB binding protein 5, histone lysine methyltransferase complex subunit
increases expression
ISO
deoxynivalenol results in increased expression of RBBP5 mRNA
CTD
PMID:19438726
NCBI chr13:46,464,389...46,494,244
Ensembl chr13:46,464,389...46,491,238
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Rbbp6
RB binding protein 6, ubiquitin ligase
increases expression
ISO
deoxynivalenol results in increased expression of RBBP6 mRNA
CTD
PMID:31863870
NCBI chr 1:186,934,563...186,966,852
Ensembl chr 1:186,934,938...186,966,852
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Rbm12
RNA binding motif protein 12
increases expression
ISO
deoxynivalenol results in increased expression of RBM12 mRNA
CTD
PMID:31863870
NCBI chr 3:165,069,744...165,089,994
Ensembl chr 3:165,042,878...165,090,021
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Rbm15
RNA binding motif protein 15
increases phosphorylation
ISO
deoxynivalenol results in increased phosphorylation of RBM15 protein
CTD
PMID:23352502
NCBI chr 2:197,634,174...197,642,697
Ensembl chr 2:197,583,002...197,643,037
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Rbm17
RNA binding motif protein 17
increases phosphorylation increases expression
ISO
deoxynivalenol results in increased phosphorylation of RBM17 protein deoxynivalenol results in increased expression of RBM17 protein
CTD
PMID:23352502 PMID:39638853
NCBI chr17:71,846,941...71,863,834
Ensembl chr17:71,846,916...71,864,431
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Rbm25
RNA binding motif protein 25
increases phosphorylation increases expression
ISO
deoxynivalenol results in increased phosphorylation of RBM25 protein deoxynivalenol results in increased expression of RBM25 protein
CTD
PMID:23352502 PMID:23811945 PMID:39638853
NCBI chr 6:108,993,119...109,050,159
Ensembl chr 6:109,002,869...109,050,159
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Rbm28
RNA binding motif protein 28
increases expression
ISO
deoxynivalenol results in increased expression of RBM28 protein
CTD
PMID:39638853
NCBI chr 4:58,688,337...58,727,312
Ensembl chr 4:58,688,337...58,726,968
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Rbm3
RNA binding motif protein 3
decreases expression
ISO
deoxynivalenol results in decreased expression of RBM3 mRNA
CTD
PMID:31863870
NCBI chr X:17,020,863...17,024,341
Ensembl chr X:17,020,864...17,024,841
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Rbm34
RNA binding motif protein 34
increases expression
ISO
deoxynivalenol results in increased expression of RBM34 protein
CTD
PMID:39638853
NCBI chr19:71,832,189...71,854,038
Ensembl chr19:71,833,763...71,853,946
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Rbm39
RNA binding motif protein 39
increases phosphorylation
ISO
deoxynivalenol results in increased phosphorylation of RBM39 protein
CTD
PMID:23811945
NCBI chr 3:165,123,087...165,156,453
Ensembl chr 3:165,123,095...165,149,397
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Rbm4
RNA binding motif protein 4
increases expression
ISO
deoxynivalenol results in increased expression of RBM4 protein
CTD
PMID:39638853
NCBI chr 1:211,507,845...211,516,907
Ensembl chr 1:211,506,343...211,516,891
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Rbm4b
RNA binding motif protein 4B
decreases expression
ISO
deoxynivalenol results in decreased expression of RBM4B protein
CTD
PMID:39638853
NCBI chr 1:211,477,337...211,487,428
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Rcc1
regulator of chromosome condensation 1
increases phosphorylation increases expression
ISO
deoxynivalenol results in increased phosphorylation of RCC1 protein deoxynivalenol results in increased expression of RCC1 protein
CTD
PMID:23352502 PMID:39638853
NCBI chr 5:149,810,037...149,828,475
Ensembl chr 5:149,810,689...149,828,523
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Rcor1
REST corepressor 1
increases expression
ISO
deoxynivalenol results in increased expression of RCOR1 mRNA
CTD
PMID:31863870
NCBI chr 6:135,890,851...135,967,367
Ensembl chr 6:135,890,851...135,967,367
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Rdh14
retinol dehydrogenase 14
increases expression
ISO
deoxynivalenol results in increased expression of RDH14 protein
CTD
PMID:39638853
NCBI chr 6:38,875,693...38,880,836
Ensembl chr 6:38,875,693...38,880,836
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Rel
REL proto-oncogene, NF-kB subunit
affects localization increases activity multiple interactions
ISO
deoxynivalenol affects the localization of REL protein deoxynivalenol results in increased activity of REL protein 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased activity of REL protein]; deoxynivalenol results in decreased activity of [REL protein binds to NFKB1 protein]
CTD
PMID:8887449 PMID:12604842 PMID:15772366
NCBI chr14:101,891,238...101,922,324
Ensembl chr14:101,891,243...101,921,938
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Rela
RELA proto-oncogene, NF-kB subunit
affects localization increases expression increases phosphorylation multiple interactions increases activity
ISO
deoxynivalenol affects the localization of RELA protein deoxynivalenol results in increased expression of RELA mRNA; deoxynivalenol results in increased expression of RELA protein deoxynivalenol results in increased phosphorylation of RELA protein Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased phosphorylation of RELA protein] [[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] affects the phosphorylation of RELA protein; ATF3 protein affects the reaction [[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] affects the phosphorylation of RELA protein]; deoxynivalenol promotes the reaction [3-aminopyridine-2-carboxaldehyde thiosemicarbazone results in increased activity of RELA protein]; deoxynivalenol promotes the reaction [3-aminopyridine-2-carboxaldehyde thiosemicarbazone results in increased phosphorylation of RELA protein]; deoxynivalenol promotes the reaction [Oxaliplatin results in increased activity of RELA protein]; deoxynivalenol promotes the reaction [Oxaliplatin results in increased phosphorylation of RELA protein]; deoxynivalenol promotes the reaction [RELA protein binds to CXCL8 promoter]; EIF2AK2 protein affects the reaction [deoxynivalenol results in increased activity of RELA protein]; Lutein inhibits the reaction [deoxynivalenol affects the localization of RELA protein]; Lutein inhibits the reaction [deoxynivalenol results in increased expression of RELA protein]; RELA protein promotes the reaction [deoxynivalenol results in increased expression of CXCL8 mRNA]; SB 203580 inhibits the reaction [deoxynivalenol results in increased activity of RELA protein]
CTD
PMID:16424113 PMID:17636245 PMID:18599499 PMID:20347963 PMID:22003189 PMID:22846391 PMID:24937323 PMID:34400200 PMID:39725263 More...
NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
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Relb
RELB proto-oncogene, NF-kB subunit
increases expression
ISO
deoxynivalenol results in increased expression of RELB mRNA
CTD
PMID:22846391
NCBI chr 1:88,385,717...88,413,380
Ensembl chr 1:88,385,717...88,413,420
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Reln
reelin
decreases expression
ISO
deoxynivalenol results in decreased expression of RELN protein
CTD
PMID:39638853
NCBI chr 4:13,628,440...14,055,201
Ensembl chr 4:13,628,399...14,055,162
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Rexo4
REX4 homolog, 3'-5' exonuclease
increases expression
ISO
deoxynivalenol results in increased expression of REXO4 protein
CTD
PMID:39638853
NCBI chr 3:30,678,729...30,692,376
Ensembl chr 3:30,678,740...30,689,059
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Rgcc
regulator of cell cycle
increases expression
ISO
deoxynivalenol results in increased expression of RGCC mRNA
CTD
PMID:31863870
NCBI chr15:61,071,574...61,084,408
Ensembl chr15:61,071,574...61,084,408
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Rgs4
regulator of G-protein signaling 4
decreases expression
ISO
deoxynivalenol results in decreased expression of RGS4 mRNA
CTD
PMID:31863870
NCBI chr13:84,469,593...84,475,884
Ensembl chr13:84,469,593...84,475,884
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Rgs5
regulator of G-protein signaling 5
decreases expression
ISO
deoxynivalenol results in decreased expression of RGS5 mRNA
CTD
PMID:31863870
NCBI chr13:84,381,077...84,417,875
Ensembl chr13:84,380,910...84,421,352
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Rhoa
ras homolog family member A
decreases expression
ISO
deoxynivalenol results in decreased expression of RHOA protein
CTD
PMID:39638853
NCBI chr 8:117,870,548...117,904,303
Ensembl chr 8:117,870,270...117,904,302
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Rhob
ras homolog family member B
increases expression
ISO
deoxynivalenol results in increased expression of RHOB protein
CTD
PMID:39638853
NCBI chr 6:37,083,030...37,085,204
Ensembl chr 6:37,075,015...37,112,772
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Rhoh
ras homolog family member H
increases expression
ISO
deoxynivalenol results in increased expression of RHOH mRNA
CTD
PMID:24247028
NCBI chr14:42,694,860...42,725,690
Ensembl chr14:42,693,413...42,749,967
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Rictor
RPTOR independent companion of MTOR, complex 2
increases expression
ISO
deoxynivalenol results in increased expression of RICTOR mRNA
CTD
PMID:31863870
NCBI chr 2:57,539,279...57,631,291
Ensembl chr 2:57,539,311...57,631,288
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Riox1
ribosomal oxygenase 1
increases expression
ISO
deoxynivalenol results in increased expression of RIOX1 protein
CTD
PMID:39638853
NCBI chr 6:109,310,748...109,313,365
Ensembl chr 6:109,286,568...109,314,355
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Riox2
ribosomal oxygenase 2
increases expression
ISO
deoxynivalenol results in increased expression of RIOX2 protein
CTD
PMID:39638853
NCBI chr11:54,327,311...54,353,989
Ensembl chr11:54,330,605...54,353,752
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Ripk2
receptor-interacting serine-threonine kinase 2
increases expression
ISO
deoxynivalenol results in increased expression of RIPK2 mRNA
CTD
PMID:22968694
NCBI chr 5:34,428,573...34,459,808
Ensembl chr 5:34,428,573...34,459,663
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Rnaset2
ribonuclease T2
decreases expression
ISO
deoxynivalenol results in decreased expression of RNASET2 mRNA
CTD
PMID:31863870
NCBI chr 1:55,133,532...55,150,701
Ensembl chr 1:55,117,492...55,150,701
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Rnf111
ring finger protein 111
increases expression
ISO
deoxynivalenol results in increased expression of RNF111 mRNA
CTD
PMID:31863870
NCBI chr 8:79,984,831...80,061,022
Ensembl chr 8:79,984,837...80,060,984
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Rnps1
RNA binding protein with serine rich domain 1
affects phosphorylation
ISO
deoxynivalenol affects the phosphorylation of RNPS1 protein
CTD
PMID:23811945
NCBI chr10:13,950,151...13,960,396
Ensembl chr10:13,950,184...13,960,393
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Rora
RAR-related orphan receptor A
increases expression
ISO
deoxynivalenol results in increased expression of RORA mRNA
CTD
PMID:24247028
NCBI chr 8:78,182,710...78,915,730
Ensembl chr 8:78,182,620...78,915,730
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Rpf1
ribosome production factor 1
increases expression
ISO
deoxynivalenol results in increased expression of RPF1 protein
CTD
PMID:39638853
NCBI chr 2:238,063,294...238,077,817
Ensembl chr 2:238,063,295...238,078,838
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Rpf2
ribosome production factor 2 homolog
increases expression
ISO
deoxynivalenol results in increased expression of RPF2 protein
CTD
PMID:39638853
NCBI chr20:45,184,511...45,205,983
Ensembl chr20:45,184,512...45,206,001
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Rpl10a
ribosomal protein L10A
increases expression
ISO
deoxynivalenol results in increased expression of RPL10A protein
CTD
PMID:39638853
NCBI chr20:6,390,533...6,393,091
Ensembl chr20:6,390,179...6,393,091
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Rpl11
ribosomal protein L11
increases expression
ISO
deoxynivalenol results in increased expression of RPL11 protein
CTD
PMID:39638853
NCBI chr 5:153,557,592...153,561,230
Ensembl chr 5:153,557,597...153,561,127
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Rpl12
ribosomal protein L12
increases expression
ISO
deoxynivalenol results in increased expression of RPL12 protein
CTD
PMID:39638853
NCBI chr 3:36,661,940...36,664,314
Ensembl chr 3:36,661,939...36,664,306
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Rpl13
ribosomal protein L13
increases expression
ISO
deoxynivalenol results in increased expression of RPL13 protein
CTD
PMID:39638853
NCBI chr19:68,062,442...68,065,065
Ensembl chr19:68,062,493...68,065,059
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Rpl13a
ribosomal protein L13A
increases expression
ISO
deoxynivalenol results in increased expression of RPL13A protein
CTD
PMID:39638853
NCBI chr 1:104,746,223...104,748,975
Ensembl chr 1:104,746,223...104,748,914
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Rpl14
ribosomal protein L14
increases expression
ISO
deoxynivalenol results in increased expression of RPL14 protein
CTD
PMID:39638853
NCBI chr 8:129,163,620...129,166,745
Ensembl chr 8:129,163,317...129,167,459
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Rpl15
ribosomal protein L15
increases expression
ISO
deoxynivalenol results in increased expression of RPL15 protein
CTD
PMID:39638853
NCBI chr15:9,934,663...9,937,946
Ensembl chr15:9,934,679...9,938,308
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Rpl17
ribosomal protein L17
increases expression
ISO
deoxynivalenol results in increased expression of RPL17 protein
CTD
PMID:39638853
NCBI chr18:70,856,275...70,859,388
Ensembl chr 3:111,722,010...111,722,638 Ensembl chr18:111,722,010...111,722,638
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Rpl18
ribosomal protein L18
increases expression
ISO
deoxynivalenol results in increased expression of RPL18 protein
CTD
PMID:39638853
NCBI chr 1:105,325,269...105,327,911
Ensembl chr 1:105,325,250...105,327,910
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Rpl18a
ribosomal protein L18A
increases expression
ISO
deoxynivalenol results in increased expression of RPL18A protein
CTD
PMID:39638853
NCBI chr16:18,576,467...18,578,653
Ensembl chr 1:70,166,729...70,167,654 Ensembl chr16:70,166,729...70,167,654
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Rpl19
ribosomal protein L19
increases expression
ISO
deoxynivalenol results in increased expression of RPL19 protein
CTD
PMID:39638853
NCBI chr10:83,514,509...83,522,352
Ensembl chr10:83,515,464...83,522,352
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Rpl21
ribosomal protein L21
increases expression
ISO
deoxynivalenol results in increased expression of RPL21 protein
CTD
PMID:39638853
NCBI chr12:13,382,516...13,386,153
Ensembl chr12:13,382,516...13,386,153 Ensembl chr13:13,382,516...13,386,153
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Rpl22l1
ribosomal protein L22 like 1
decreases expression
ISO
deoxynivalenol results in decreased expression of RPL22L1 mRNA
CTD
PMID:31863870
NCBI chr 2:113,683,196...113,685,132
Ensembl chr 2:113,683,196...113,685,132
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Rpl23
ribosomal protein L23
increases expression
ISO
deoxynivalenol results in increased expression of RPL23 protein
CTD
PMID:39638853
NCBI chr10:83,268,223...83,272,184
Ensembl chr10:83,262,592...83,272,214
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Rpl24
ribosomal protein L24
increases expression
ISO
deoxynivalenol results in increased expression of RPL24 protein
CTD
PMID:39638853
NCBI chr11:58,122,997...58,128,405
Ensembl chr11:58,122,997...58,128,405
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Rpl27
ribosomal protein L27
increases expression
ISO
deoxynivalenol results in increased expression of RPL27 protein
CTD
PMID:39638853
NCBI chr10:86,875,758...86,879,457
Ensembl chr10:86,876,024...86,879,441
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Rpl27a
ribosomal protein L27A
decreases expression
ISO
deoxynivalenol results in decreased expression of RPL27A mRNA
CTD
PMID:24247028
NCBI chr 1:172,971,957...172,977,591
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Rpl28
ribosomal protein L28
increases expression
ISO
deoxynivalenol results in increased expression of RPL28 protein
CTD
PMID:39638853
NCBI chr 1:78,080,945...78,083,532
Ensembl chr 1:78,080,945...78,083,771
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Rpl29
ribosomal protein L29
increases expression
ISO
deoxynivalenol results in increased expression of RPL29 protein
CTD
PMID:39638853
NCBI chr 8:115,056,443...115,949,677
Ensembl chr 8:115,947,394...115,950,565
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Rpl3
ribosomal protein L3
increases expression
ISO
deoxynivalenol results in increased expression of RPL3 protein
CTD
PMID:39638853
NCBI chr 7:113,491,943...113,508,115
Ensembl chr 7:113,501,960...113,507,990
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Rpl30
ribosomal protein L30
increases expression
ISO
deoxynivalenol results in increased expression of RPL30 protein
CTD
PMID:39638853
NCBI chr 7:67,533,420...67,536,555
Ensembl chr 7:67,465,332...67,536,555
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Rpl31
ribosomal protein L31
decreases expression increases expression
ISO
deoxynivalenol results in decreased expression of RPL31 mRNA deoxynivalenol results in increased expression of RPL31 protein
CTD
PMID:31863870 PMID:39638853
NCBI chr 9:49,143,044...49,147,155
Ensembl chr 9:49,142,955...49,147,155
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Rpl35
ribosomal protein L35
increases expression
ISO
deoxynivalenol results in increased expression of RPL35 protein
CTD
PMID:39638853
NCBI chr 3:43,162,960...43,166,485
Ensembl chr 3:43,162,764...43,165,947
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Rpl35a
ribosomal protein L35A
increases expression
ISO
deoxynivalenol results in increased expression of RPL35A protein
CTD
PMID:39638853
NCBI chr11:81,231,114...81,235,094
Ensembl chr 5:163,826,849...163,827,306 Ensembl chr11:163,826,849...163,827,306
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Rpl4
ribosomal protein L4
increases phosphorylation
ISO
deoxynivalenol results in increased phosphorylation of RPL4 protein
CTD
PMID:23352502
NCBI chr 8:73,566,477...73,571,600
Ensembl chr 8:73,566,466...73,571,788
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Rpl5
ribosomal protein L5
increases expression
ISO
deoxynivalenol results in increased expression of RPL5 protein
CTD
PMID:39638853
NCBI chr14:1,988,792...1,995,236
Ensembl chr14:1,988,793...1,995,225
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Rpl6
ribosomal protein L6
increases expression
ISO
deoxynivalenol results in increased expression of RPL6 protein
CTD
PMID:39638853
NCBI chr12:41,008,142...41,012,756
Ensembl chr12:41,008,142...41,025,733
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Rpl7
ribosomal protein L7
increases expression
ISO
deoxynivalenol results in increased expression of RPL7 protein
CTD
PMID:39638853
NCBI chr 5:8,000,446...8,003,454
Ensembl chr 5:7,850,630...8,003,451
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Rpl7a
ribosomal protein L7A
increases expression
ISO
deoxynivalenol results in increased expression of RPL7A protein
CTD
PMID:39638853
NCBI chr 3:30,637,136...30,639,778
Ensembl chr 3:30,637,059...30,639,791 Ensembl chr18:30,637,059...30,639,791
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Rpl7l1
ribosomal protein L7-like 1
increases expression
ISO
deoxynivalenol results in increased expression of RPL7L1 protein
CTD
PMID:39638853
NCBI chr 9:21,695,718...21,703,736
Ensembl chr 9:21,695,707...21,703,735
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Rpl8
ribosomal protein L8
increases expression
ISO
deoxynivalenol results in increased expression of RPL8 protein
CTD
PMID:39638853
NCBI chr 7:110,506,815...110,509,106
Ensembl chr 7:110,506,800...110,509,103 Ensembl chr 3:110,506,800...110,509,103
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Rplp0
ribosomal protein lateral stalk subunit P0
decreases phosphorylation
ISO
deoxynivalenol results in decreased phosphorylation of RPLP0 protein
CTD
PMID:23352502 PMID:23811945
NCBI chr12:46,715,121...46,718,390
Ensembl chr12:46,715,124...46,718,422
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Rplp1
ribosomal protein lateral stalk subunit P1
decreases phosphorylation increases phosphorylation
ISO
deoxynivalenol results in decreased phosphorylation of RPLP1 protein deoxynivalenol results in increased phosphorylation of RPLP1 protein
CTD
PMID:23352502 PMID:23811945
NCBI chr 8:71,289,539...71,290,872
Ensembl chr 8:71,289,535...71,290,872
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Rplp2
ribosomal protein lateral stalk subunit P2
decreases phosphorylation increases phosphorylation
ISO
deoxynivalenol results in decreased phosphorylation of RPLP2 protein deoxynivalenol results in increased phosphorylation of RPLP2 protein
CTD
PMID:23352502 PMID:23811945
NCBI chr 1:205,975,598...205,978,192
Ensembl chr 1:205,975,894...205,978,191
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Rpp30
ribonuclease P/MRP subunit p30
increases expression
ISO
deoxynivalenol results in increased expression of RPP30 mRNA
CTD
PMID:31863870
NCBI chr 1:243,198,647...243,221,559
Ensembl chr 1:243,198,713...243,221,553
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Rps12
ribosomal protein S12
increases expression
ISO
deoxynivalenol results in increased expression of RPS12 protein
CTD
PMID:39638853
NCBI chr 1:23,499,943...23,502,234
Ensembl chr 1:23,500,073...23,502,235
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Rps14
ribosomal protein S14
increases expression
ISO
deoxynivalenol results in increased expression of RPS14 protein
CTD
PMID:39638853
NCBI chr18:56,492,010...56,503,092
Ensembl chr18:56,498,245...56,503,091
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Rps16
ribosomal protein S16
increases expression
ISO
deoxynivalenol results in increased expression of RPS16 protein
CTD
PMID:39638853
NCBI chr 1:92,770,658...92,773,603
Ensembl chr19:56,922,246...56,923,020 Ensembl chr 1:56,922,246...56,923,020
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Rps24
ribosomal protein S24
increases expression
ISO
deoxynivalenol results in increased expression of RPS24 protein
CTD
PMID:39638853
NCBI chr16:95,429...101,146
Ensembl chr16:96,484...101,144
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Rps28
ribosomal protein S28
increases expression
ISO
deoxynivalenol results in increased expression of RPS28 protein
CTD
PMID:39638853
NCBI chr 7:15,309,964...15,311,333
Ensembl chr16:72,591,164...72,591,373 Ensembl chr 7:72,591,164...72,591,373 Ensembl chr16:72,591,164...72,591,373
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Rps29
ribosomal protein S29
decreases expression
ISO
deoxynivalenol results in decreased expression of RPS29 mRNA
CTD
PMID:31863870
NCBI chr 6:93,371,293...93,372,731
Ensembl chr13:87,816,954...87,817,267 Ensembl chr 6:87,816,954...87,817,267
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Rps3a
ribosomal protein S3a
increases expression
ISO
deoxynivalenol results in increased expression of RPS3A protein
CTD
PMID:39638853
NCBI chr 2:173,822,673...173,827,042
Ensembl chr 2:173,822,488...173,827,043
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Rps4x
ribosomal protein S4, X-linked
increases expression
ISO
deoxynivalenol results in increased expression of RPS4X protein
CTD
PMID:39638853
NCBI chr X:71,338,478...71,342,921
Ensembl chr X:71,338,479...71,342,921 Ensembl chr 4:71,338,479...71,342,921
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Rps5
ribosomal protein S5
increases expression
ISO
deoxynivalenol results in increased expression of RPS5 protein
CTD
PMID:39638853
NCBI chr 1:82,610,965...82,615,262
Ensembl chr 1:82,610,965...82,615,262
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Rps6
ribosomal protein S6
decreases phosphorylation increases expression multiple interactions
ISO
deoxynivalenol results in decreased phosphorylation of RPS6 protein deoxynivalenol results in increased expression of RPS6 protein lauric acid inhibits the reaction [deoxynivalenol results in decreased phosphorylation of RPS6 protein]
CTD
PMID:34506767 PMID:39638853
NCBI chr 5:106,417,680...106,420,540
Ensembl chr 5:106,417,680...106,420,566
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Rps6ka1
ribosomal protein S6 kinase A1
multiple interactions increases phosphorylation
ISO
4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased phosphorylation of RPS6KA1 protein]; deoxynivalenol results in increased phosphorylation of and results in increased activity of RPS6KA1 protein
CTD
PMID:15772366 PMID:15976193
NCBI chr 5:151,362,819...151,402,064
Ensembl chr 5:151,362,819...151,476,044
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Rps6ka2
ribosomal protein S6 kinase A2
increases phosphorylation
ISO
deoxynivalenol results in increased phosphorylation of RPS6KA2 protein
CTD
PMID:16424113
NCBI chr 1:55,178,988...55,454,271
Ensembl chr 1:55,179,319...55,454,338
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Rps6ka5
ribosomal protein S6 kinase A5
increases phosphorylation
ISO
deoxynivalenol results in increased phosphorylation of RPS6KA5 protein
CTD
PMID:16424113
NCBI chr 6:125,558,434...125,736,576
Ensembl chr 6:125,558,434...125,735,856
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Rps6kb1
ribosomal protein S6 kinase B1
decreases phosphorylation multiple interactions
ISO
deoxynivalenol results in decreased phosphorylation of RPS6KB1 protein lauric acid inhibits the reaction [deoxynivalenol results in decreased phosphorylation of RPS6KB1 protein]
CTD
PMID:34506767
NCBI chr10:71,817,794...71,865,211
Ensembl chr10:71,815,614...71,865,238
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Rps8
ribosomal protein S8
increases expression
ISO
deoxynivalenol results in increased expression of RPS8 protein
CTD
PMID:39638853
NCBI chr 5:135,866,941...135,869,511
Ensembl chr 5:135,866,941...135,869,548
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Rrbp1
ribosome binding protein 1
decreases expression
ISO
deoxynivalenol results in decreased expression of RRBP1 protein
CTD
PMID:39638853
NCBI chr 3:151,768,386...151,830,255
Ensembl chr 3:151,768,386...151,830,255
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Rrm2b
ribonucleotide reductase regulatory TP53 inducible subunit M2B
increases expression
ISO
deoxynivalenol results in increased expression of RRM2B mRNA
CTD
PMID:31863870
NCBI chr 7:70,962,008...70,993,726
Ensembl chr 7:70,965,590...70,993,670
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Rrp1
ribosomal RNA processing 1
increases expression
ISO
deoxynivalenol results in increased expression of RRP1 protein
CTD
PMID:39638853
NCBI chr20:10,260,580...10,271,829
Ensembl chr20:10,260,592...10,275,076
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Rrp12
ribosomal RNA processing 12
increases expression
ISO
deoxynivalenol results in increased expression of RRP12 protein
CTD
PMID:39638853
NCBI chr 1:250,621,707...250,655,318
Ensembl chr 1:250,621,707...250,655,318
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Rrp1b
ribosomal RNA processing 1B
increases expression
ISO
deoxynivalenol results in increased expression of RRP1B protein
CTD
PMID:39638853
NCBI chr20:10,122,825...10,148,404
Ensembl chr20:10,122,812...10,148,404
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Rrp8
ribosomal RNA processing 8
increases expression
ISO
deoxynivalenol results in increased expression of RRP8 protein
CTD
PMID:39638853
NCBI chr 1:169,489,829...169,500,551
Ensembl chr 1:169,465,397...169,501,164
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Rrp9
ribosomal RNA processing 9, U3 small nucleolar RNA binding protein
increases expression
ISO
deoxynivalenol results in increased expression of RRP9 protein
CTD
PMID:39638853
NCBI chr 8:115,995,119...116,004,832
Ensembl chr 8:115,996,169...116,004,824
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Rrs1
ribosome biogenesis regulator 1 homolog
increases expression
ISO
deoxynivalenol results in increased expression of RRS1 protein
CTD
PMID:39638853
NCBI chr 5:14,516,303...14,517,936
Ensembl chr 5:14,515,254...14,517,943
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Rsl1d1
ribosomal L1 domain containing 1
increases expression
ISO
deoxynivalenol results in increased expression of RSL1D1 mRNA; deoxynivalenol results in increased expression of RSL1D1 protein
CTD
PMID:24247028 PMID:39638853
NCBI chr10:4,931,839...4,943,726
Ensembl chr10:4,904,792...4,946,566
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Rsl24d1
ribosomal L24 domain containing 1
increases expression
ISO
deoxynivalenol results in increased expression of RSL24D1 protein
CTD
PMID:39638853
NCBI chr 8:82,733,627...82,742,632
Ensembl chr 8:82,733,649...82,744,497
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RT1-CE16
RT1 class I, locus CE16
decreases expression
ISO
deoxynivalenol results in decreased expression of HLA-A protein
CTD
PMID:39638853
NCBI chr20:3,261,656...3,265,548
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Rtn4
reticulon 4
increases expression
ISO
deoxynivalenol results in increased expression of RTN4 protein
CTD
PMID:39638853
NCBI chr14:107,651,001...107,698,610
Ensembl chr14:107,650,732...107,698,611
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Ruvbl2
RuvB-like AAA ATPase 2
increases expression
ISO
deoxynivalenol results in increased expression of RUVBL2 mRNA
CTD
PMID:31863870
NCBI chr 1:105,038,487...105,051,851
Ensembl chr 1:105,038,174...105,051,720
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S100a4
S100 calcium-binding protein A4
decreases expression
ISO
deoxynivalenol results in decreased expression of S100A4 mRNA
CTD
PMID:31863870
NCBI chr 2:178,388,529...178,390,838
Ensembl chr 2:178,388,526...178,390,837
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Safb
scaffold attachment factor B
increases phosphorylation
ISO
deoxynivalenol results in increased phosphorylation of SAFB protein
CTD
PMID:23352502
NCBI chr 9:1,504,657...1,525,545
Ensembl chr 9:1,504,456...1,525,781
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Samhd1
SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
affects phosphorylation
ISO
deoxynivalenol affects the phosphorylation of SAMHD1 protein
CTD
PMID:23811945
NCBI chr 3:166,179,742...166,214,448
Ensembl chr 3:166,181,588...166,214,410
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Sart1
spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP
increases expression
ISO
deoxynivalenol results in increased expression of SART1 protein
CTD
PMID:39638853
NCBI chr 1:212,119,824...212,128,517
Ensembl chr 1:212,104,557...212,128,486
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Scara5
scavenger receptor class A, member 5
decreases expression
ISO
deoxynivalenol results in decreased expression of SCARA5 mRNA
CTD
PMID:26763390
NCBI chr15:44,055,576...44,160,593
Ensembl chr15:44,055,630...44,160,585
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Scd
stearoyl-CoA desaturase
decreases expression
ISO
deoxynivalenol results in decreased expression of SCD protein
CTD
PMID:39638853
NCBI chr 1:253,218,968...253,232,101
Ensembl chr 1:253,218,970...253,231,785
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Scfd1
sec1 family domain containing 1
increases expression
ISO
deoxynivalenol results in increased expression of SCFD1 protein
CTD
PMID:39638853
NCBI chr 6:74,531,225...74,609,463
Ensembl chr 6:74,531,276...74,633,750
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Sclt1
sodium channel and clathrin linker 1
increases expression
ISO
deoxynivalenol results in increased expression of SCLT1 mRNA
CTD
PMID:31863870
NCBI chr 2:126,533,436...126,691,879
Ensembl chr 2:126,533,560...126,691,971
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Sdc1
syndecan 1
decreases expression
ISO
deoxynivalenol results in decreased expression of SDC1 protein
CTD
PMID:33890134
NCBI chr 6:37,282,041...37,304,503
Ensembl chr 6:37,297,010...37,304,500
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Sec24a
SEC24 homolog A, COPII coat complex component
decreases expression
ISO
deoxynivalenol results in decreased expression of SEC24A protein
CTD
PMID:39638853
NCBI chr10:36,450,043...36,525,303
Ensembl chr10:36,450,043...36,525,303
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Sec61b
SEC61 translocon subunit beta
decreases phosphorylation
ISO
deoxynivalenol results in decreased phosphorylation of SEC61B protein
CTD
PMID:23352502
NCBI chr 5:66,569,184...66,577,394
Ensembl chr 5:66,569,196...66,580,028
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Sel1l
SEL1L adaptor subunit of SYVN1 ubiquitin ligase
decreases expression
ISO
deoxynivalenol results in decreased expression of SEL1L protein
CTD
PMID:39638853
NCBI chr 6:116,466,163...116,510,436
Ensembl chr 6:116,466,163...116,510,578
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Sema3a
semaphorin 3A
decreases expression
ISO
deoxynivalenol results in decreased expression of SEMA3A mRNA
CTD
PMID:26763390
NCBI chr 4:22,239,418...22,709,907
Ensembl chr 4:22,245,322...22,535,774
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Serinc1
serine incorporator 1
decreases expression
ISO
deoxynivalenol results in decreased expression of SERINC1 protein
CTD
PMID:39638853
NCBI chr20:37,396,497...37,415,433
Ensembl chr20:37,396,497...37,443,124
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Serpina1
serpin family A member 1
decreases expression
ISO
deoxynivalenol results in decreased expression of SERPINA1 protein
CTD
PMID:39638853
NCBI chr 6:128,631,101...128,653,125
Ensembl chr 6:128,619,382...128,660,703
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Serpina3n
serpin family A member 3N
decreases expression
ISO
deoxynivalenol results in decreased expression of SERPINA3 mRNA
CTD
PMID:31863870
NCBI chr 6:129,088,392...129,095,950
Ensembl chr 6:129,088,398...129,097,415
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Serpine2
serpin family E member 2
decreases expression
ISO
deoxynivalenol results in decreased expression of SERPINE2 mRNA
CTD
PMID:31863870
NCBI chr 9:88,573,138...88,637,252
Ensembl chr 9:88,573,149...88,637,202
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Serpinf1
serpin family F member 1
decreases expression
ISO
deoxynivalenol results in decreased expression of SERPINF1 protein
CTD
PMID:39638853
NCBI chr10:60,748,504...60,760,898
Ensembl chr10:60,748,506...60,760,898
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Setd1a
SET domain containing 1A, histone lysine methyltransferase
increases phosphorylation
ISO
deoxynivalenol results in increased phosphorylation of SETD1A protein
CTD
PMID:23352502
NCBI chr 1:191,818,752...191,842,167
Ensembl chr 1:191,818,752...191,842,160
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Sf1
splicing factor 1
increases phosphorylation increases expression
ISO
deoxynivalenol results in increased phosphorylation of SF1 protein deoxynivalenol results in increased expression of SF1 protein
CTD
PMID:23811945 PMID:39638853
NCBI chr 1:213,090,256...213,112,688
Ensembl chr 1:213,099,260...213,113,590
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Sf3a1
splicing factor 3A subunit 1
increases expression
ISO
deoxynivalenol results in increased expression of SF3A1 mRNA
CTD
PMID:31863870
NCBI chr14:83,254,971...83,275,720
Ensembl chr14:83,254,971...83,275,720
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Sf3a2
splicing factor 3A subunit 2
increases expression
ISO
deoxynivalenol results in increased expression of SF3A2 protein
CTD
PMID:39638853
NCBI chr 7:9,560,182...9,566,205
Ensembl chr 7:9,560,182...9,566,205
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Sfpq
splicing factor proline and glutamine rich
increases expression
ISO
deoxynivalenol results in increased expression of SFPQ protein
CTD
PMID:39638853
NCBI chr 5:144,621,678...144,637,930
Ensembl chr 5:144,622,476...144,637,926
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Sft2d2
SFT2 domain containing 2
decreases expression
ISO
deoxynivalenol results in decreased expression of SFT2D2 mRNA
CTD
PMID:31863870
NCBI chr13:80,017,854...80,037,144
Ensembl chr13:80,008,480...80,037,473
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Sfxn3
sideroflexin 3
decreases expression
ISO
deoxynivalenol results in decreased expression of SFXN3 protein
CTD
PMID:39638853
NCBI chr 1:253,856,935...253,866,219
Ensembl chr 1:253,856,882...253,887,542
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Sgpp1
sphingosine-1-phosphate phosphatase 1
decreases phosphorylation
ISO
deoxynivalenol results in decreased phosphorylation of SGPP1 protein
CTD
PMID:23811945
NCBI chr 6:100,161,024...100,182,214
Ensembl chr 6:100,161,024...100,182,259
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Sh2d3c
SH2 domain containing 3C
affects phosphorylation
ISO
deoxynivalenol affects the phosphorylation of SH2D3C protein
CTD
PMID:23811945
NCBI chr 3:36,408,305...36,444,191
Ensembl chr 3:36,408,304...36,444,716
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Sh3bp1
SH3-domain binding protein 1
increases phosphorylation
ISO
deoxynivalenol results in increased phosphorylation of SH3BP1 protein
CTD
PMID:23352502
NCBI chr 7:112,338,087...112,350,659
Ensembl chr 7:112,338,107...112,350,659
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Sh3kbp1
SH3 domain-containing kinase-binding protein 1
increases phosphorylation
ISO
deoxynivalenol results in increased phosphorylation of SH3KBP1 protein
CTD
PMID:23811945
NCBI chr X:38,686,530...39,031,658
Ensembl chr X:38,686,530...39,031,393
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Shcbp1
SHC binding and spindle associated 1
increases expression
ISO
deoxynivalenol results in increased expression of SHCBP1 mRNA
CTD
PMID:31863870
NCBI chr16:91,373,843...91,405,409
Ensembl chr16:91,373,871...91,405,409
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Shox1
SHOX homeobox 1
decreases expression
ISO
deoxynivalenol results in decreased expression of SHOX mRNA
CTD
PMID:26763390
NCBI chr X:121,553,770...121,560,788
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Shpk
sedoheptulokinase
decreases expression
ISO
deoxynivalenol results in decreased expression of SHPK protein
CTD
PMID:39638853
NCBI chr10:58,316,065...58,340,489
Ensembl chr10:58,316,111...58,340,490
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Sirt1
sirtuin 1
increases expression multiple interactions
ISO
deoxynivalenol results in increased expression of SIRT1 mRNA 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in increased expression of SIRT1 mRNA]
CTD
PMID:34677630
NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,305,476...25,328,000
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Slc10a2
solute carrier family 10 member 2
multiple interactions decreases expression
ISO
GW 4064 inhibits the reaction [deoxynivalenol results in decreased expression of SLC10A2 mRNA]; SB 203580 inhibits the reaction [deoxynivalenol results in decreased expression of SLC10A2 mRNA]
CTD
PMID:35224661 PMID:37315771
NCBI chr16:91,088,089...91,111,025
Ensembl chr16:91,076,423...91,111,025
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Slc11a2
solute carrier family 11 member 2
decreases expression
ISO
deoxynivalenol results in decreased expression of SLC11A2 protein
CTD
PMID:39638853
NCBI chr 7:133,381,878...133,429,921
Ensembl chr 7:133,381,878...133,418,941
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Slc16a1
solute carrier family 16 member 1
increases phosphorylation
ISO
deoxynivalenol results in increased phosphorylation of SLC16A1 protein
CTD
PMID:23811945
NCBI chr 2:194,805,556...194,832,966
Ensembl chr 2:194,812,502...194,832,977
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Slc1a3
solute carrier family 1 member 3
affects localization
EXP
deoxynivalenol affects the localization of SLC1A3 protein
CTD
PMID:21748807
NCBI chr 2:59,482,707...59,557,808
Ensembl chr 2:59,482,709...59,557,808
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Slc1a4
solute carrier family 1 member 4
decreases expression
ISO
deoxynivalenol results in decreased expression of SLC1A4 protein
CTD
PMID:39638853
NCBI chr14:98,718,646...98,761,672
Ensembl chr14:98,730,450...98,761,790
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Slc1a5
solute carrier family 1 member 5
decreases expression
ISO
deoxynivalenol results in decreased expression of SLC1A5 mRNA; deoxynivalenol results in decreased expression of SLC1A5 protein
CTD
PMID:31863870 PMID:39638853
NCBI chr 1:86,584,949...86,599,052
Ensembl chr 1:86,584,949...86,599,054
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Slc25a5-ps11
solute carrier family 25 member 5, pseudogene 11
decreases expression
ISO
deoxynivalenol results in decreased expression of SLC25A6 mRNA
CTD
PMID:31863870
NCBI chr18:70,846,358...70,847,597
Ensembl chr18:70,846,358...70,847,597
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Slc29a1
solute carrier family 29 member 1
decreases expression
ISO
deoxynivalenol results in decreased expression of SLC29A1 protein
CTD
PMID:39638853
NCBI chr 9:22,897,099...22,911,640
Ensembl chr 9:22,902,471...22,914,620
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Slc2a1
solute carrier family 2 member 1
decreases expression
ISO
deoxynivalenol results in decreased expression of SLC2A1 protein
CTD
PMID:39638853
NCBI chr 5:138,002,522...138,030,742
Ensembl chr 5:138,002,522...138,030,742
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Slc33a1
solute carrier family 33 member 1
decreases expression
ISO
deoxynivalenol results in decreased expression of SLC33A1 protein
CTD
PMID:39638853
NCBI chr 2:150,565,327...150,587,700
Ensembl chr 2:150,565,328...150,587,416
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Slc38a3
solute carrier family 38, member 3
decreases expression
ISO
deoxynivalenol results in decreased expression of SLC38A3 protein
CTD
PMID:39638853
NCBI chr 8:117,202,534...117,220,310
Ensembl chr 8:117,202,536...117,218,630
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Slc39a4
solute carrier family 39 member 4
decreases expression
ISO
deoxynivalenol results in decreased expression of SLC39A4 protein
CTD
PMID:39638853
NCBI chr 7:110,214,017...110,218,202
Ensembl chr 7:110,214,017...110,218,202
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Slc3a2
solute carrier family 3 member 2
decreases expression
ISO
deoxynivalenol results in decreased expression of SLC3A2 protein
CTD
PMID:38040082 PMID:39638853
NCBI chr 1:215,033,601...215,048,064
Ensembl chr 1:215,033,601...215,048,064
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Slc44a1
solute carrier family 44 member 1
decreases expression
ISO
deoxynivalenol results in decreased expression of SLC44A1 protein
CTD
PMID:39638853
NCBI chr 5:72,857,323...73,037,279
Ensembl chr 5:72,858,759...73,037,279
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Slc4a1ap
solute carrier family 4 member 1 adaptor protein
increases expression
ISO
deoxynivalenol results in increased expression of SLC4A1AP mRNA
CTD
PMID:31863870
NCBI chr 6:30,625,931...30,653,859
Ensembl chr 6:30,625,931...30,653,792
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Slc4a7
solute carrier family 4 member 7
increases expression
ISO
deoxynivalenol results in increased expression of SLC4A7 mRNA; deoxynivalenol results in increased expression of SLC4A7 protein
CTD
PMID:31863870 PMID:39638853
NCBI chr15:13,015,854...13,095,485
Ensembl chr15:13,015,854...13,095,292
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Slc51a
solute carrier family 51 member A
decreases expression
ISO
deoxynivalenol results in decreased expression of SLC51A mRNA
CTD
PMID:35224661
NCBI chr11:81,804,141...81,818,539
Ensembl chr11:81,803,972...81,818,539
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Slc7a11
solute carrier family 7 member 11
decreases expression increases expression multiple interactions
ISO
deoxynivalenol results in decreased expression of SLC7A11 mRNA; deoxynivalenol results in decreased expression of SLC7A11 protein deoxynivalenol results in increased expression of SLC7A11 protein NNMT protein promotes the reaction [deoxynivalenol results in decreased expression of SLC7A11 protein]; Resveratrol inhibits the reaction [deoxynivalenol results in decreased expression of SLC7A11 protein]
CTD
PMID:31863870 PMID:37419272 PMID:38040082 PMID:39147090 PMID:39983889
NCBI chr 2:136,532,912...136,668,560
Ensembl chr 2:136,532,246...136,695,695
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Sltm
SAFB-like, transcription modulator
increases expression
ISO
deoxynivalenol results in increased expression of SLTM protein
CTD
PMID:39638853
NCBI chr 8:80,096,555...80,142,668
Ensembl chr 8:80,097,652...80,142,671
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Smarca4
SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4
increases expression
ISO
deoxynivalenol results in increased expression of SMARCA4 protein
CTD
PMID:39638853
NCBI chr 8:28,438,370...28,535,071
Ensembl chr 8:28,443,810...28,535,070
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Smarcc1
SWI/SNF related BAF chromatin remodeling complex subunit C1
increases expression
ISO
deoxynivalenol results in increased expression of SMARCC1 protein
CTD
PMID:39638853
NCBI chr 8:118,986,917...119,093,161
Ensembl chr 8:118,989,516...119,093,152
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Smarcc2
SWI/SNF related BAF chromatin remodeling complex subunit C2
increases phosphorylation
ISO
deoxynivalenol results in increased phosphorylation of SMARCC2 protein
CTD
PMID:23352502
NCBI chr 7:1,466,223...1,494,627
Ensembl chr 7:1,466,454...1,494,626
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Smarcd1
SWI/SNF related BAF chromatin remodeling complex subunit D1
increases expression
ISO
deoxynivalenol results in increased expression of SMARCD1 protein
CTD
PMID:39638853
NCBI chr 7:132,708,627...132,719,167
Ensembl chr 7:132,708,432...132,719,167
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Smarce1
SWI/SNF related BAF chromatin remodeling complex subunit E1
increases expression
ISO
deoxynivalenol results in increased expression of SMARCE1 protein
CTD
PMID:39638853
NCBI chr10:84,655,468...84,678,259
Ensembl chr10:84,655,468...84,676,185
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Smchd1
structural maintenance of chromosomes flexible hinge domain containing 1
increases expression
ISO
deoxynivalenol results in increased expression of SMCHD1 protein
CTD
PMID:39638853
NCBI chr 9:118,690,050...118,837,281
Ensembl chr 9:118,690,057...118,833,452
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Smox
spermine oxidase
increases expression
ISO
deoxynivalenol results in increased expression of SMOX mRNA
CTD
PMID:26763390
NCBI chr 3:139,184,793...139,220,174
Ensembl chr 3:139,184,798...139,220,170 Ensembl chr X:139,184,798...139,220,170
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Snip1
Smad nuclear interacting protein 1
affects phosphorylation
ISO
deoxynivalenol affects the phosphorylation of SNIP1 protein
CTD
PMID:23352502
NCBI chr 5:142,613,028...142,620,502
Ensembl chr 5:142,613,004...142,620,527
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Snu13
small nuclear ribonucleoprotein 13
increases expression
ISO
deoxynivalenol results in increased expression of SNU13 protein
CTD
PMID:39638853
NCBI chr 7:115,445,415...115,451,008
Ensembl chr 1:269,702,002...269,703,004 Ensembl chr 7:269,702,002...269,703,004
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Snw1
SNW domain containing 1
decreases phosphorylation increases expression
ISO
deoxynivalenol results in decreased phosphorylation of SNW1 protein deoxynivalenol results in increased expression of SNW1 mRNA
CTD
PMID:23352502 PMID:31863870
NCBI chr 6:112,826,374...112,850,459
Ensembl chr 6:112,826,381...112,858,180
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Socs1
suppressor of cytokine signaling 1
increases expression multiple interactions
ISO
deoxynivalenol results in increased expression of SOCS1 mRNA deoxynivalenol inhibits the reaction [Antigens results in increased expression of SOCS1 mRNA]
CTD
PMID:19625342 PMID:28935500
NCBI chr10:5,389,574...5,391,265
Ensembl chr10:5,389,334...5,391,847
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Socs2
suppressor of cytokine signaling 2
increases expression multiple interactions
ISO
deoxynivalenol results in increased expression of SOCS2 mRNA deoxynivalenol inhibits the reaction [Antigens results in increased expression of SOCS2 mRNA]
CTD
PMID:19625342 PMID:28935500
NCBI chr 7:31,890,564...31,932,092
Ensembl chr 7:31,874,463...31,930,423
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Socs3
suppressor of cytokine signaling 3
increases expression multiple interactions
ISO
deoxynivalenol results in increased expression of SOCS3 mRNA; deoxynivalenol results in increased expression of SOCS3 protein deoxynivalenol promotes the reaction [IL10 protein results in increased expression of SOCS3 mRNA]; deoxynivalenol promotes the reaction [IL10 protein results in increased expression of SOCS3 protein]
CTD
PMID:19625342 PMID:19805407 PMID:38432439
NCBI chr10:103,692,579...103,695,975
Ensembl chr10:103,690,976...103,704,825
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Sod1
superoxide dismutase 1
decreases expression multiple interactions
ISO
deoxynivalenol results in decreased expression of SOD1 mRNA Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of SOD1 mRNA]
CTD
PMID:35817260
NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399
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Sod2
superoxide dismutase 2
decreases expression increases expression
ISO
deoxynivalenol results in decreased expression of SOD2 mRNA deoxynivalenol results in increased expression of SOD2 mRNA
CTD
PMID:20702593 PMID:35314294
NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168
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Son
SON DNA and RNA binding protein
increases expression
ISO
deoxynivalenol results in increased expression of SON protein
CTD
PMID:39638853
NCBI chr11:44,336,818...44,409,127
Ensembl chr11:44,377,976...44,409,127
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Sorbs2
sorbin and SH3 domain containing 2
decreases phosphorylation
ISO
deoxynivalenol results in decreased phosphorylation of SORBS2 protein
CTD
PMID:23811945
NCBI chr16:53,167,795...53,481,300
Ensembl chr16:53,167,827...53,358,986
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Sort1
sortilin 1
decreases expression
ISO
deoxynivalenol results in decreased expression of SORT1 protein
CTD
PMID:39638853
NCBI chr 2:198,609,466...198,690,481
Ensembl chr 2:198,612,148...198,690,481
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Sox4
SRY-box transcription factor 4
increases expression
ISO
deoxynivalenol results in increased expression of SOX4 mRNA
CTD
PMID:22846391
NCBI chr17:35,876,298...35,881,004
Ensembl chr17:35,875,756...35,884,024
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Sox5
SRY-box transcription factor 5
increases expression
ISO
deoxynivalenol results in increased expression of SOX5 mRNA
CTD
PMID:23792671
NCBI chr 4:178,512,272...179,467,686
Ensembl chr 4:178,512,272...178,938,495
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Sp1
Sp1 transcription factor
multiple interactions affects expression increases phosphorylation
ISO
deoxynivalenol promotes the reaction [SP1 protein binds to KMT2A promoter]; SP1 protein promotes the reaction [deoxynivalenol results in increased expression of KMT2A mRNA] deoxynivalenol affects the expression of SP1 protein deoxynivalenol results in increased phosphorylation of SP1 protein
CTD
PMID:19438726 PMID:33890134
NCBI chr 7:135,419,864...135,450,513
Ensembl chr 7:135,420,050...135,450,513
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Sp100
SP100 nuclear antigen
decreases phosphorylation
ISO
deoxynivalenol results in decreased phosphorylation of SP100 protein
CTD
PMID:23811945
NCBI chr 9:93,758,975...93,825,068
Ensembl chr 9:93,759,075...93,825,068
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Spag5
sperm associated antigen 5
increases expression
ISO
deoxynivalenol results in increased expression of SPAG5 mRNA
CTD
PMID:31863870
NCBI chr10:63,693,300...63,714,813
Ensembl chr10:63,696,466...63,714,811
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Spp1
secreted phosphoprotein 1
decreases phosphorylation increases expression
ISO
deoxynivalenol results in decreased phosphorylation of SPP1 protein deoxynivalenol results in increased expression of SPP1 mRNA
CTD
PMID:23352502 PMID:27757495
NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,613,576...5,619,820
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Sprr1a
small proline-rich protein 1A
decreases expression
ISO
deoxynivalenol results in decreased expression of SPRR1A protein
CTD
PMID:33890134
NCBI chr 2:180,750,709...180,752,625
Ensembl chr 2:180,750,709...180,752,991
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Sprr3
small proline-rich protein 3
increases expression
ISO
deoxynivalenol results in increased expression of SPRR3 mRNA
CTD
PMID:23792671
NCBI chr 2:180,723,038...180,725,695
Ensembl chr 2:180,723,061...180,725,505
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Sptlc2
serine palmitoyltransferase, long chain base subunit 2
decreases expression
ISO
deoxynivalenol results in decreased expression of SPTLC2 mRNA
CTD
PMID:31863870
NCBI chr 6:112,679,623...112,762,470
Ensembl chr 6:112,679,623...112,762,640
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Sptlc3
serine palmitoyltransferase, long chain base subunit 3
decreases expression
ISO
deoxynivalenol results in decreased expression of SPTLC3 protein
CTD
PMID:39638853
NCBI chr 3:147,301,570...147,431,696
Ensembl chr 3:147,301,801...147,434,044
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Sqstm1
sequestosome 1
increases expression
ISO
deoxynivalenol results in increased expression of SQSTM1 mRNA; deoxynivalenol results in increased expression of SQSTM1 protein
CTD
PMID:31863870 PMID:39638853
NCBI chr10:35,026,598...35,037,750
Ensembl chr10:35,026,598...35,037,750
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Srfbp1
serum response factor binding protein 1
increases expression
ISO
deoxynivalenol results in increased expression of SRFBP1 mRNA
CTD
PMID:31863870
NCBI chr18:48,118,740...48,139,824
Ensembl chr18:48,117,375...48,140,864
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Srrm1
serine and arginine repetitive matrix 1
increases phosphorylation affects phosphorylation decreases phosphorylation
ISO
deoxynivalenol results in increased phosphorylation of SRRM1 protein deoxynivalenol affects the phosphorylation of SRRM1 protein deoxynivalenol results in decreased phosphorylation of SRRM1 protein
CTD
PMID:23352502 PMID:23811945
NCBI chr 5:152,843,167...152,875,554
Ensembl chr 5:152,843,169...152,875,436
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Srrm2
serine/arginine repetitive matrix 2
affects phosphorylation
ISO
deoxynivalenol affects the phosphorylation of SRRM2 protein
CTD
PMID:23352502 PMID:23811945
NCBI chr10:13,320,059...13,353,337
Ensembl chr10:13,320,059...13,353,337
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Srsf1
serine and arginine rich splicing factor 1
decreases phosphorylation increases expression increases phosphorylation
ISO
deoxynivalenol results in decreased phosphorylation of SRSF1 protein deoxynivalenol results in increased expression of SRSF1 protein deoxynivalenol results in increased phosphorylation of SRSF1 protein
CTD
PMID:23352502 PMID:23811945 PMID:39638853
NCBI chr10:73,335,519...73,342,549
Ensembl chr10:73,336,422...73,342,548
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Srsf11
serine and arginine rich splicing factor 11
increases expression
ISO
deoxynivalenol results in increased expression of SRSF11 protein
CTD
PMID:39638853
NCBI chr 2:249,733,464...249,760,296
Ensembl chr 2:249,733,464...249,760,499
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Srsf2
serine and arginine rich splicing factor 2
affects phosphorylation increases expression
ISO
deoxynivalenol affects the phosphorylation of SRSF2 protein deoxynivalenol results in increased expression of SRSF2 protein
CTD
PMID:23811945 PMID:39638853
NCBI chr10:102,550,962...102,554,200
Ensembl chr10:102,553,072...102,554,141
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Srsf7
serine and arginine rich splicing factor 7
increases expression
ISO
deoxynivalenol results in increased expression of SRSF7 protein
CTD
PMID:39638853
NCBI chr 6:20,564,035...20,571,205
Ensembl chr 6:20,564,044...20,571,212
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Srsf9
serine and arginine rich splicing factor 9
decreases phosphorylation increases phosphorylation
ISO
deoxynivalenol results in decreased phosphorylation of SRSF9 protein deoxynivalenol results in increased phosphorylation of SRSF9 protein
CTD
PMID:23352502 PMID:23811945
NCBI chr12:46,938,948...46,945,213
Ensembl chr12:46,938,950...46,945,283
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Ssrp1
structure specific recognition protein 1
affects phosphorylation
ISO
deoxynivalenol affects the phosphorylation of SSRP1 protein
CTD
PMID:23811945
NCBI chr 3:90,531,024...90,541,132
Ensembl chr 3:90,530,829...90,541,129
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St6gal1
ST6 beta-galactoside alpha-2,6-sialyltransferase 1
decreases expression
ISO
deoxynivalenol results in decreased expression of ST6GAL1 protein
CTD
PMID:39638853
NCBI chr11:91,031,481...91,158,111
Ensembl chr11:91,032,450...91,040,415
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Star
steroidogenic acute regulatory protein
multiple interactions
ISO
[Colforsin co-treated with deoxynivalenol] results in increased expression of STAR mRNA
CTD
PMID:26783879
NCBI chr16:72,969,824...72,974,447
Ensembl chr16:72,961,518...72,974,447
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Stat1
signal transducer and activator of transcription 1
multiple interactions increases expression increases phosphorylation
ISO
[deoxynivalenol results in increased susceptibility to Antigens] which results in increased expression of STAT1 mRNA; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [deoxynivalenol results in increased expression of STAT1 mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [deoxynivalenol results in increased phosphorylation of STAT1 protein]; stattic inhibits the reaction [deoxynivalenol results in increased expression of STAT1 mRNA]; stattic inhibits the reaction [deoxynivalenol results in increased phosphorylation of STAT1 protein]
CTD
PMID:22454431 PMID:28935500
NCBI chr 9:56,911,522...56,951,926
Ensembl chr 9:56,911,523...57,077,346
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Stat2
signal transducer and activator of transcription 2
increases expression
ISO
deoxynivalenol results in increased expression of STAT2 mRNA
CTD
PMID:22454431
NCBI chr 7:1,287,025...1,302,858
Ensembl chr 7:1,287,024...1,303,459
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Stat3
signal transducer and activator of transcription 3
multiple interactions increases phosphorylation increases expression
ISO
alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [deoxynivalenol promotes the reaction [IL10 protein results in increased phosphorylation of STAT3 mRNA]]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [deoxynivalenol promotes the reaction [IL10 protein results in increased phosphorylation of STAT3 protein]]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [deoxynivalenol results in increased expression of STAT3 mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [deoxynivalenol results in increased phosphorylation of STAT3 protein]; deoxynivalenol promotes the reaction [IL10 protein results in increased phosphorylation of STAT3 mRNA]; deoxynivalenol promotes the reaction [IL10 protein results in increased phosphorylation of STAT3 protein]; stattic inhibits the reaction [deoxynivalenol results in increased expression of STAT3 mRNA]; stattic inhibits the reaction [deoxynivalenol results in increased phosphorylation of STAT3 protein]
CTD
PMID:22454431 PMID:36602574 PMID:38432439
NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359
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Stat4
signal transducer and activator of transcription 4
multiple interactions
ISO
[deoxynivalenol results in increased susceptibility to Antigens] which results in increased expression of STAT4 mRNA
CTD
PMID:28935500
NCBI chr 9:56,964,617...57,080,523
Ensembl chr 9:56,911,523...57,077,346
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Steap3
STEAP3 metalloreductase
increases phosphorylation
ISO
deoxynivalenol results in increased phosphorylation of STEAP3 protein
CTD
PMID:23811945
NCBI chr13:33,904,710...33,950,100
Ensembl chr13:33,904,710...33,950,080
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Stmn1
stathmin 1
increases phosphorylation
ISO
deoxynivalenol results in increased phosphorylation of STMN1 protein
CTD
PMID:23352502 PMID:23811945
NCBI chr 5:151,964,308...151,970,843
Ensembl chr 5:151,964,351...151,970,842
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Stom
stomatin
increases expression
ISO
deoxynivalenol results in increased expression of STOM protein
CTD
PMID:39638853
NCBI chr 3:39,042,503...39,064,818
Ensembl chr 3:39,042,503...39,064,818
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Strap
serine/threonine kinase receptor associated protein
increases expression
ISO
deoxynivalenol results in increased expression of STRAP protein
CTD
PMID:39638853
NCBI chr 4:172,377,325...172,391,573
Ensembl chr 4:172,377,305...172,392,436
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Strbp
spermatid perinuclear RNA binding protein
increases expression
ISO
deoxynivalenol results in increased expression of STRBP mRNA
CTD
PMID:31863870
NCBI chr 3:41,738,096...41,879,054
Ensembl chr 3:41,712,311...41,824,707
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Strip1
striatin interacting protein 1
decreases phosphorylation
ISO
deoxynivalenol results in decreased phosphorylation of STRIP1 protein
CTD
PMID:23811945
NCBI chr 2:197,936,569...197,956,515
Ensembl chr 2:197,936,569...197,956,865
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Sulf1
sulfatase 1
decreases expression
ISO
deoxynivalenol results in decreased expression of SULF1 mRNA
CTD
PMID:31863870
NCBI chr 5:11,145,950...11,308,622
Ensembl chr 5:11,145,950...11,308,643
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Sult1a1
sulfotransferase family 1A member 1
decreases expression
ISO
deoxynivalenol results in decreased expression of SULT1A1 protein
CTD
PMID:39638853
NCBI chr 1:190,702,592...190,706,112
Ensembl chr 1:190,702,592...190,706,131
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Sult2a1
sulfotransferase family 2A member 1
decreases expression
ISO
deoxynivalenol results in decreased expression of SULT2A1 protein
CTD
PMID:39638853
NCBI chr 1:84,582,011...84,639,001
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Sumo2
small ubiquitin-like modifier 2
increases expression
ISO
deoxynivalenol results in increased expression of SUMO2 protein
CTD
PMID:39638853
NCBI chr10:101,270,899...101,283,458
Ensembl chr10:101,270,900...101,283,938 Ensembl chr 5:101,270,900...101,283,938
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Sun2
Sad1 and UNC84 domain containing 2
decreases expression
ISO
deoxynivalenol results in decreased expression of SUN2 protein
CTD
PMID:39638853
NCBI chr 7:113,155,766...113,172,950
Ensembl chr 7:113,155,766...113,172,940
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Surf6
surfeit 6
increases expression
ISO
deoxynivalenol results in increased expression of SURF6 protein
CTD
PMID:39638853
NCBI chr 3:30,619,525...30,630,388
Ensembl chr 3:30,619,530...30,630,247
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Sybu
syntabulin
decreases expression
ISO
deoxynivalenol results in decreased expression of SYBU mRNA
CTD
PMID:31863870
NCBI chr 7:77,731,662...77,833,413
Ensembl chr 7:77,731,605...77,833,686
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Synm
synemin
affects phosphorylation
ISO
deoxynivalenol affects the phosphorylation of SYNM protein
CTD
PMID:23811945
NCBI chr 1:130,743,891...130,774,254
Ensembl chr 1:130,743,897...130,773,824
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Synpo2
synaptopodin 2
affects phosphorylation
ISO
deoxynivalenol affects the phosphorylation of SYNPO2 protein
CTD
PMID:23811945
NCBI chr 2:213,901,685...214,055,844
Ensembl chr 2:213,900,868...214,055,844
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Tap1
transporter 1, ATP binding cassette subfamily B member
decreases expression
ISO
deoxynivalenol results in decreased expression of TAP1 mRNA; deoxynivalenol results in decreased expression of TAP1 protein
CTD
PMID:15766417
NCBI chr20:4,658,171...4,668,543
Ensembl chr20:4,658,172...4,668,810
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Tbc1d15
TBC1 domain family, member 15
decreases phosphorylation
ISO
deoxynivalenol results in decreased phosphorylation of TBC1D15 protein
CTD
PMID:23352502
NCBI chr 7:52,690,770...52,746,309
Ensembl chr 7:52,690,770...52,746,303
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Tbl3
transducin (beta)-like 3
increases expression
ISO
deoxynivalenol results in increased expression of TBL3 protein
CTD
PMID:39638853
NCBI chr10:14,230,660...14,235,873
Ensembl chr10:14,230,661...14,235,873
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Tbp
TATA box binding protein
increases expression
ISO
deoxynivalenol results in increased expression of TBP protein
CTD
PMID:33890134
NCBI chr 1:65,136,420...65,153,515
Ensembl chr 1:65,136,448...65,190,899
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Tcea3
transcription elongation factor A3
decreases expression
ISO
deoxynivalenol results in decreased expression of TCEA3 protein
CTD
PMID:39638853
NCBI chr 5:153,760,401...153,792,934
Ensembl chr 5:153,760,407...153,792,930
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Tcof1
treacle ribosome biogenesis factor 1
decreases phosphorylation
ISO
deoxynivalenol results in decreased phosphorylation of TCOF1 protein
CTD
PMID:23811945
NCBI chr18:56,537,437...56,570,727
Ensembl chr18:56,537,437...56,570,727
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Tf
transferrin
multiple interactions decreases expression
ISO
[deoxynivalenol co-treated with Zearalenone] affects the expression of TF mRNA; [deoxynivalenol co-treated with Zearalenone] results in increased expression of TF mRNA deoxynivalenol results in decreased expression of TF mRNA; deoxynivalenol results in decreased expression of TF protein
CTD
PMID:28865950 PMID:28935499 PMID:39638853
NCBI chr 8:112,668,667...112,695,376
Ensembl chr 8:112,647,642...112,695,400
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Tfap4
transcription factor AP-4
decreases phosphorylation
ISO
deoxynivalenol results in decreased phosphorylation of TFAP4 protein
CTD
PMID:23352502
NCBI chr10:11,507,242...11,525,794
Ensembl chr10:11,485,565...11,525,794
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Tfcp2l1
transcription factor CP2-like 1
decreases expression
ISO
deoxynivalenol results in decreased expression of TFCP2L1 protein
CTD
PMID:33890134
NCBI chr13:32,286,643...32,346,671
Ensembl chr13:32,286,643...32,346,671
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Tff1
trefoil factor 1
affects expression increases expression multiple interactions decreases secretion
ISO
deoxynivalenol affects the expression of TFF1 mRNA deoxynivalenol results in increased expression of TFF1 mRNA 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one affects the reaction [deoxynivalenol affects the expression of TFF1 mRNA]; Adenine affects the reaction [deoxynivalenol affects the expression of TFF1 mRNA]; afimoxifene inhibits the reaction [deoxynivalenol results in increased expression of TFF1 mRNA]; deoxynivalenol promotes the reaction [Estradiol results in increased expression of TFF1 mRNA]; deoxynivalenol promotes the reaction [Zearalenone results in increased expression of TFF1 mRNA]; ESR1 promotes the reaction [deoxynivalenol results in increased expression of TFF1 mRNA]; SB 203580 affects the reaction [deoxynivalenol affects the expression of TFF1 mRNA] deoxynivalenol results in decreased secretion of TFF1 protein
CTD
PMID:30854615 PMID:35588983
NCBI chr20:9,237,095...9,240,956
Ensembl chr20:9,237,095...9,240,956
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Tff2
trefoil factor 2
decreases secretion multiple interactions affects expression
ISO
deoxynivalenol results in decreased secretion of TFF2 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one affects the reaction [deoxynivalenol affects the expression of TFF2 mRNA]; Adenine affects the reaction [deoxynivalenol affects the expression of TFF2 mRNA]; SB 203580 affects the reaction [deoxynivalenol affects the expression of TFF2 mRNA]
CTD
PMID:30854615
NCBI chr20:9,217,110...9,220,979
Ensembl chr20:9,217,121...9,220,979
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Tff3
trefoil factor 3
multiple interactions affects expression decreases secretion
ISO
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one affects the reaction [deoxynivalenol affects the expression of TFF3 mRNA]; Adenine affects the reaction [deoxynivalenol affects the expression of TFF3 mRNA]; SB 203580 affects the reaction [deoxynivalenol affects the expression of TFF3 mRNA] deoxynivalenol results in decreased secretion of TFF3 protein
CTD
PMID:30854615
NCBI chr20:9,194,623...9,199,333
Ensembl chr20:9,194,626...9,199,333
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Tfrc
transferrin receptor
increases expression decreases expression
ISO
deoxynivalenol results in increased expression of TFRC mRNA deoxynivalenol results in decreased expression of TFRC protein
CTD
PMID:37419272 PMID:39638853 PMID:39983889
NCBI chr11:81,668,478...81,690,318
Ensembl chr11:81,668,478...81,690,318
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Tgfb1
transforming growth factor, beta 1
multiple interactions increases expression
ISO
deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of TGFB1 mRNA] deoxynivalenol results in increased expression of TGFB1 mRNA
CTD
PMID:14644621
NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899
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Tgfb3
transforming growth factor, beta 3
multiple interactions increases expression
ISO
deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of TGFB3 mRNA] deoxynivalenol results in increased expression of TGFB3 mRNA
CTD
PMID:14644621
NCBI chr 6:111,435,170...111,457,646
Ensembl chr 6:111,435,170...111,456,946
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Tgfbr2
transforming growth factor, beta receptor 2
decreases expression
ISO
deoxynivalenol results in decreased expression of TGFBR2 protein
CTD
PMID:39638853
NCBI chr 8:124,672,677...124,761,741
Ensembl chr 8:124,674,986...124,761,469
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Tgfbr3
transforming growth factor beta receptor 3
decreases expression
ISO
deoxynivalenol results in decreased expression of TGFBR3 protein
CTD
PMID:39638853
NCBI chr14:2,634,294...2,810,269
Ensembl chr14:2,634,188...2,810,271
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Thrap3
thyroid hormone receptor associated protein 3
increases phosphorylation
ISO
deoxynivalenol results in increased phosphorylation of THRAP3 protein
CTD
PMID:23352502 PMID:23811945
NCBI chr 5:143,729,821...143,772,105
Ensembl chr 5:143,730,596...143,771,983
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Thrb
thyroid hormone receptor beta
multiple interactions decreases activity
ISO
[15-acetyldeoxynivalenol co-treated with 3-acetyldeoxynivalenol co-treated with deoxynivalenol co-treated with zearalenol co-treated with Zearalenone] results in decreased activity of THRB protein; deoxynivalenol inhibits the reaction [Triiodothyronine results in increased activity of THRB protein] deoxynivalenol results in decreased activity of THRB protein
CTD
PMID:27481073 PMID:31077750
NCBI chr15:10,115,954...10,465,231
Ensembl chr15:10,115,954...10,313,680
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Timm9
translocase of inner mitochondrial membrane 9
increases expression
ISO
deoxynivalenol results in increased expression of TIMM9 protein
CTD
PMID:39638853
NCBI chr 6:95,346,065...95,358,895
Ensembl chr 6:95,346,065...95,358,895
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Timp3
TIMP metallopeptidase inhibitor 3
decreases expression
ISO
deoxynivalenol results in decreased expression of TIMP3 mRNA
CTD
PMID:31863870
NCBI chr 7:19,408,539...19,459,558
Ensembl chr 7:19,409,631...19,459,547
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Tjp1
tight junction protein 1
affects localization multiple interactions decreases expression increases expression
ISO
deoxynivalenol affects the localization of TJP1 protein 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide promotes the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of TJP1 mRNA]]; 6-formylindolo(3,2-b)carbazole inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of TJP1 mRNA]]; 6-formylindolo(3,2-b)carbazole inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of TJP1 protein]]; Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of and affects the localization of TJP1 protein]; Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of TJP1 mRNA]; deoxynivalenol results in decreased expression of and affects the localization of TJP1 protein; lauric acid inhibits the reaction [deoxynivalenol results in decreased expression of TJP1 protein]; sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of TJP1 mRNA]; sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of TJP1 protein] deoxynivalenol results in decreased expression of TJP1 mRNA; deoxynivalenol results in decreased expression of TJP1 protein deoxynivalenol results in increased expression of TJP1 mRNA
CTD
PMID:24568843 PMID:34506767 PMID:35381244 PMID:35817260
NCBI chr 1:128,260,330...128,505,018
Ensembl chr 1:128,260,330...128,505,158
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Tkfc
triokinase and FMN cyclase
decreases expression
ISO
deoxynivalenol results in decreased expression of TKFC protein
CTD
PMID:39638853
NCBI chr 1:216,664,446...216,677,815
Ensembl chr 1:216,661,477...216,677,928
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Tlr1
toll-like receptor 1
decreases expression
ISO
deoxynivalenol results in decreased expression of TLR1 mRNA
CTD
PMID:26763390
NCBI chr14:43,737,761...43,750,389
Ensembl chr14:43,740,379...43,756,243
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Tlr2
toll-like receptor 2
decreases expression
ISO
deoxynivalenol results in decreased expression of TLR2 mRNA
CTD
PMID:22968694
NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:171,497,060...171,520,194
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Tlr3
toll-like receptor 3
decreases expression
ISO
deoxynivalenol results in decreased expression of TLR3 mRNA
CTD
PMID:22968694
NCBI chr16:53,554,916...53,572,321
Ensembl chr16:53,555,131...53,568,385
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Tlr4
toll-like receptor 4
increases expression
ISO
deoxynivalenol results in increased expression of TLR4 mRNA; deoxynivalenol results in increased expression of TLR4 protein
CTD
PMID:34400200
NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007
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Tlr5
toll-like receptor 5
increases expression
ISO
deoxynivalenol results in increased expression of TLR5 mRNA
CTD
PMID:22968694
NCBI chr13:97,166,430...97,190,642
Ensembl chr13:97,166,405...97,192,525
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Tm9sf2
transmembrane 9 superfamily member 2
decreases expression
ISO
deoxynivalenol results in decreased expression of TM9SF2 protein
CTD
PMID:39638853
NCBI chr15:105,606,082...105,660,715
Ensembl chr15:105,606,118...105,660,714
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Tm9sf3
transmembrane 9 superfamily member 3
decreases expression
ISO
deoxynivalenol results in decreased expression of TM9SF3 mRNA
CTD
PMID:31863870
NCBI chr 1:249,981,458...250,034,247
Ensembl chr 1:249,981,458...250,034,247
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Tm9sf4
transmembrane 9 superfamily member 4
decreases expression
ISO
deoxynivalenol results in decreased expression of TM9SF4 protein
CTD
PMID:39638853
NCBI chr 3:162,086,758...162,135,620
Ensembl chr 3:162,087,347...162,151,721
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Tmbim6
transmembrane BAX inhibitor motif containing 6
decreases expression
ISO
deoxynivalenol results in decreased expression of TMBIM6 protein
CTD
PMID:33890134
NCBI chr 7:132,405,217...132,422,492
Ensembl chr 7:132,386,134...132,422,492
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Tmpo
thymopoietin
affects phosphorylation increases expression
ISO
deoxynivalenol affects the phosphorylation of TMPO protein deoxynivalenol results in increased expression of TMPO protein
CTD
PMID:23811945 PMID:39638853
NCBI chr 7:27,529,977...27,554,980
Ensembl chr 7:27,529,978...27,554,937
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Tmt1a
thiol methyltransferase 1A
decreases expression
ISO
deoxynivalenol results in decreased expression of TMT1A protein
CTD
PMID:39638853
NCBI chr 7:133,330,141...133,377,172
Ensembl chr 7:133,330,447...133,338,959
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Tmt1b
thiol methyltransferase 1B
decreases expression
ISO
deoxynivalenol results in decreased expression of TMT1B protein
CTD
PMID:39638853
NCBI chr 7:1,973,334...1,975,980
Ensembl chr 7:1,973,337...1,975,980
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Tmx3
thioredoxin-related transmembrane protein 3
increases expression
ISO
deoxynivalenol results in increased expression of TMX3 protein
CTD
PMID:39638853
NCBI chr18:86,021,137...86,054,025
Ensembl chr18:86,021,084...86,054,198
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Tnf
tumor necrosis factor
multiple interactions increases secretion increases expression increases stability
ISO EXP
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased secretion of TNF protein]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in increased expression of TNF mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in increased secretion of TNF protein]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide promotes the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of TNF mRNA]]; 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased expression of TNF protein]; 6-formylindolo(3,2-b)carbazole inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of TNF mRNA]]; [deoxynivalenol co-treated with Aflatoxin B1] results in decreased expression of TNF mRNA; [deoxynivalenol results in increased susceptibility to Antigens] which results in increased expression of TNF protein; [Lipopolysaccharides co-treated with deoxynivalenol] results in increased expression of TNF protein; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [deoxynivalenol promotes the reaction [IL10 protein results in increased expression of TNF mRNA]]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [deoxynivalenol results in increased expression of TNF mRNA]; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased expression of TNF mRNA]; BMAL1 protein inhibits the reaction [deoxynivalenol results in increased expression of TNF protein]; Celecoxib inhibits the reaction [deoxynivalenol results in increased expression of TNF protein]; Curcumin inhibits the reaction [deoxynivalenol results in increased expression of TNF mRNA]; deoxynivalenol promotes the reaction [IL10 protein results in increased expression of TNF mRNA]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; Dichlororibofuranosylbenzimidazole inhibits the reaction [deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased secretion of TNF protein]]; HCK protein affects the reaction [deoxynivalenol results in increased expression of TNF protein]; HMOX1 protein inhibits the reaction [deoxynivalenol results in increased expression of TNF protein]; Lipopolysaccharides promotes the reaction [deoxynivalenol results in increased expression of TNF mRNA]; Lipopolysaccharides promotes the reaction [deoxynivalenol results in increased expression of TNF protein]; Poly I-C promotes the reaction [deoxynivalenol results in increased expression of TNF mRNA]; pyrazolanthrone inhibits the reaction [deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]]; resiquimod promotes the reaction [deoxynivalenol results in increased expression of TNF mRNA]; Rolipram inhibits the reaction [[Lipopolysaccharides co-treated with deoxynivalenol] results in increased expression of TNF protein]; SB 203580 inhibits the reaction [deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]]; SB 203580 inhibits the reaction [deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased secretion of TNF protein]]; SB 203580 inhibits the reaction [deoxynivalenol results in increased expression of TNF mRNA]; SB 203580 inhibits the reaction [deoxynivalenol results in increased secretion of TNF protein]; sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of TNF mRNA]; stattic inhibits the reaction [deoxynivalenol results in increased expression of TNF mRNA]; Zymosan promotes the reaction [deoxynivalenol results in increased expression of TNF mRNA] deoxynivalenol results in increased expression of TNF mRNA; deoxynivalenol results in increased expression of TNF protein Bentonite inhibits the reaction [deoxynivalenol results in increased expression of TNF mRNA]; Bentonite inhibits the reaction [deoxynivalenol results in increased expression of TNF protein]; Charcoal inhibits the reaction [deoxynivalenol results in increased expression of TNF mRNA]; Charcoal inhibits the reaction [deoxynivalenol results in increased expression of TNF protein]; deoxynivalenol inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; Adenine inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased abundance of Nitric Oxide]; deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]; lactacystin inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; Oxaliplatin promotes the reaction [deoxynivalenol results in increased expression of TNF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; SB 203580 inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]] deoxynivalenol results in increased stability of TNF mRNA
CTD
PMID:9194413 PMID:9707511 PMID:10344227 PMID:11295263 PMID:11922776 PMID:12604842 PMID:14644621 PMID:15772366 PMID:16009389 PMID:16687389 PMID:17090620 PMID:18433975 PMID:18614267 PMID:19625342 PMID:21748807 PMID:21873375 PMID:22454431 PMID:22968694 PMID:24793808 PMID:24937323 PMID:25392278 PMID:25549547 PMID:25766886 PMID:26115597 PMID:27757495 PMID:28935500 PMID:31034930 PMID:32416088 PMID:32738333 PMID:33170220 PMID:34400200 PMID:35314294 PMID:35381244 PMID:35817260 PMID:35925383 PMID:36602574 PMID:38432439 PMID:38763499 PMID:39725263 More...
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
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Tnfsf14
TNF superfamily member 14
increases expression
ISO
deoxynivalenol results in increased expression of TNFSF14 mRNA
CTD
PMID:22968694
NCBI chr 9:2,155,270...2,160,100
Ensembl chr 9:2,155,270...2,160,191
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Tnfsf9
TNF superfamily member 9
decreases expression
ISO
deoxynivalenol results in decreased expression of TNFSF9 mRNA
CTD
PMID:24247028
NCBI chr 9:2,031,011...2,033,345
Ensembl chr 9:2,030,953...2,033,339
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Tns1
tensin 1
decreases phosphorylation
ISO
deoxynivalenol results in decreased phosphorylation of TNS1 protein
CTD
PMID:23811945
NCBI chr 9:82,941,068...83,152,007
Ensembl chr 9:82,941,068...83,152,007
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Tns3
tensin 3
decreases expression
ISO
deoxynivalenol results in decreased expression of TNS3 protein
CTD
PMID:39638853
NCBI chr14:87,387,441...87,619,457
Ensembl chr14:87,387,441...87,619,712
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Toe1
target of EGR1, exonuclease
increases expression
ISO
deoxynivalenol results in increased expression of TOE1 protein
CTD
PMID:39638853
NCBI chr 5:135,507,116...135,510,682
Ensembl chr 5:135,507,116...135,510,682
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Tomm20
translocase of outer mitochondrial membrane 20
affects localization increases phosphorylation
ISO
deoxynivalenol affects the localization of TOMM20 protein deoxynivalenol results in increased phosphorylation of TOMM20 protein
CTD
PMID:33890134
NCBI chr19:71,822,429...71,832,420
Ensembl chr19:71,822,411...71,832,510
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Tomm22
translocase of outer mitochondrial membrane 22
decreases expression
ISO
deoxynivalenol results in decreased expression of TOMM22 protein
CTD
PMID:33890134
NCBI chr 7:113,103,863...113,109,056
Ensembl chr 7:113,103,860...113,109,053
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Tomm40
translocase of outer mitochondrial membrane 40
decreases expression
ISO
deoxynivalenol results in decreased expression of TOMM40 protein
CTD
PMID:33890134
NCBI chr 1:88,486,745...88,498,833
Ensembl chr 1:88,486,758...88,499,671
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Tomm70
translocase of outer mitochondrial membrane 70
increases phosphorylation decreases expression
ISO
deoxynivalenol results in increased phosphorylation of TOMM70A protein deoxynivalenol results in decreased expression of TOMM70A protein
CTD
PMID:23352502 PMID:33890134
NCBI chr11:56,847,837...56,886,302
Ensembl chr11:56,846,334...56,886,320
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Top1
DNA topoisomerase I
increases expression
ISO
deoxynivalenol results in increased expression of TOP1 protein
CTD
PMID:39638853
NCBI chr 3:169,713,195...169,796,330
Ensembl chr 3:169,713,130...169,796,327
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Top2b
DNA topoisomerase II beta
increases phosphorylation
ISO
deoxynivalenol results in increased phosphorylation of TOP2B protein
CTD
PMID:23811945
NCBI chr15:11,482,089...11,542,464
Ensembl chr15:11,482,089...11,542,464
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Tp53
tumor protein p53
multiple interactions increases expression decreases expression increases activity
ISO
[pifithrin results in decreased activity of TP53 protein] which results in decreased susceptibility to deoxynivalenol; Curcumin inhibits the reaction [deoxynivalenol results in increased expression of TRP53 protein]; deoxynivalenol results in increased phosphorylation of and results in increased activity of TRP53 protein; pifithrin inhibits the reaction [deoxynivalenol results in increased phosphorylation of and results in increased activity of TRP53 protein]; SB 203580 inhibits the reaction [deoxynivalenol results in increased phosphorylation of and results in increased activity of TRP53 protein] deoxynivalenol results in decreased expression of TP53 protein deoxynivalenol results in increased expression of TP53 mRNA [Zearalenone co-treated with Aflatoxin B1] promotes the reaction [deoxynivalenol results in increased expression of TP53 mRNA]; Aflatoxin B1 promotes the reaction [deoxynivalenol results in increased expression of TP53 mRNA] deoxynivalenol results in increased activity of TP53 protein
CTD
PMID:15976193 PMID:19664677 PMID:22491426 PMID:30668976 PMID:33890134 PMID:35817260 More...
NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
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Tp53inp1
tumor protein p53 inducible nuclear protein 1
increases expression
ISO
deoxynivalenol results in increased expression of TP53INP1 mRNA
CTD
PMID:31863870
NCBI chr 5:29,051,267...29,069,486
Ensembl chr 5:29,051,264...29,069,484
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Tpm4
tropomyosin 4
increases expression
ISO
deoxynivalenol results in increased expression of TPM4 protein
CTD
PMID:39638853
NCBI chr16:17,718,442...17,732,483
Ensembl chr16:17,717,230...17,732,494
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Tpt1
tumor protein, translationally-controlled 1
increases expression
ISO
deoxynivalenol results in increased expression of TPT1 protein
CTD
PMID:39638853
NCBI chr15:57,562,217...57,568,968
Ensembl chr15:57,566,067...57,569,554
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Tpx2
TPX2, microtubule nucleation factor
increases expression
ISO
deoxynivalenol results in increased expression of TPX2 protein
CTD
PMID:39638853
NCBI chr 3:161,778,709...161,820,941
Ensembl chr 3:161,778,742...161,820,724
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Traf1
TNF receptor-associated factor 1
increases expression
ISO
deoxynivalenol results in increased expression of TRAF1 mRNA
CTD
PMID:22846391
NCBI chr 3:38,607,707...38,639,641
Ensembl chr 3:38,619,506...38,636,264
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Traf6
TNF receptor associated factor 6
increases expression
ISO
deoxynivalenol results in increased expression of TRAF6 mRNA
CTD
PMID:22846391 PMID:34400200
NCBI chr 3:108,418,537...108,443,330
Ensembl chr 3:108,418,513...108,443,328
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Trib3
tribbles pseudokinase 3
decreases expression
ISO
deoxynivalenol results in decreased expression of TRIB3 mRNA
CTD
PMID:23253260 PMID:31863870
NCBI chr 3:161,269,939...161,275,533
Ensembl chr 3:161,269,955...161,274,802
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Trim28
tripartite motif-containing 28
increases phosphorylation increases expression
ISO
deoxynivalenol results in increased phosphorylation of TRIM28 protein deoxynivalenol results in increased expression of TRIM28 protein
CTD
PMID:23352502 PMID:39638853
NCBI chr 1:82,724,842...82,731,566
Ensembl chr 1:82,724,838...82,731,572
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Trmt13
tRNA methyltransferase 13 homolog
increases expression
ISO
deoxynivalenol results in increased expression of TRMT13 mRNA
CTD
PMID:22846391
NCBI chr 2:207,217,399...207,232,467
Ensembl chr 2:207,218,552...207,231,701
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Trmt1l
tRNA methyltransferase 1-like
increases expression
ISO
deoxynivalenol results in increased expression of TRMT1L protein
CTD
PMID:39638853
NCBI chr13:66,060,186...66,093,247
Ensembl chr13:66,060,162...66,093,643
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Trmt6
tRNA methyltransferase 6 non-catalytic subunit
increases expression
ISO
deoxynivalenol results in increased expression of TRMT6 protein
CTD
PMID:39638853
NCBI chr 3:140,527,785...140,539,520
Ensembl chr 3:140,527,788...140,539,509
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Trmt61a
tRNA methyltransferase 61A
increases expression
ISO
deoxynivalenol results in increased expression of TRMT61A protein
CTD
PMID:39638853
NCBI chr 6:136,558,417...136,564,411
Ensembl chr 6:136,558,391...136,564,410
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Trpa1
transient receptor potential cation channel, subfamily A, member 1
multiple interactions
ISO
TRPA1 affects the reaction [deoxynivalenol results in increased secretion of CCK protein]
CTD
PMID:25787141
NCBI chr 5:9,163,060...9,217,325
Ensembl chr 5:9,163,060...9,217,325
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Tslp
thymic stromal lymphopoietin
multiple interactions
ISO
deoxynivalenol promotes the reaction [Antigens, Dermatophagoides results in increased expression of TSLP protein]
CTD
PMID:33170220
NCBI chr18:24,723,990...24,728,419
Ensembl chr18:24,720,257...24,728,420
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Ttk
Ttk protein kinase
increases expression
ISO
deoxynivalenol results in increased expression of TTK mRNA
CTD
PMID:31863870
NCBI chr 8:93,632,678...93,672,664
Ensembl chr 8:93,634,319...93,672,664
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Ttr
transthyretin
decreases expression
ISO
deoxynivalenol results in decreased expression of TTR protein
CTD
PMID:39638853
NCBI chr18:12,216,684...12,225,972
Ensembl chr18:12,216,732...12,225,969
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Txndc11
thioredoxin domain containing 11
decreases expression
ISO
deoxynivalenol results in decreased expression of TXNDC11 mRNA
CTD
PMID:23253260
NCBI chr10:5,022,464...5,079,958
Ensembl chr10:5,022,435...5,079,950
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Txndc16
thioredoxin domain containing 16
increases phosphorylation
ISO
deoxynivalenol results in increased phosphorylation of TXNDC16 protein
CTD
PMID:23352502
NCBI chr15:20,831,541...20,905,661
Ensembl chr15:20,831,391...20,905,452
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Ube2c
ubiquitin-conjugating enzyme E2C
increases expression
ISO
deoxynivalenol results in increased expression of UBE2C mRNA
CTD
PMID:31863870
NCBI chr 3:173,925,975...173,928,375
Ensembl chr 3:173,925,934...173,932,678
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Ufsp2
UFM1-specific peptidase 2
increases expression
ISO
deoxynivalenol results in increased expression of UFSP2 protein
CTD
PMID:39638853
NCBI chr16:53,004,590...53,023,640
Ensembl chr16:53,004,598...53,023,592
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Ugt2a3
UDP glucuronosyltransferase family 2 member A3
decreases expression
ISO
deoxynivalenol results in decreased expression of UGT2A3 protein
CTD
PMID:39638853
NCBI chr14:20,851,970...20,869,974
Ensembl chr14:20,851,969...20,869,973
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Ugt2b7
UDP glucuronosyltransferase family 2 member B7
increases glucuronidation
ISO
UGT2B7 protein results in increased glucuronidation of deoxynivalenol
CTD
PMID:24927789
NCBI chr14:21,251,535...21,274,451
Ensembl chr14:21,251,535...21,274,451
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Uhrf1
ubiquitin-like with PHD and ring finger domains 1
affects phosphorylation
ISO
deoxynivalenol affects the phosphorylation of UHRF1 protein
CTD
PMID:23352502
NCBI chr 9:1,220,162...1,241,792
Ensembl chr 9:1,222,063...1,241,792
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Unc13d
unc-13 homolog D
decreases phosphorylation
ISO
deoxynivalenol results in decreased phosphorylation of UNC13D protein
CTD
PMID:23811945
NCBI chr10:101,795,652...101,810,409
Ensembl chr10:101,795,652...101,810,409
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Upf2
UPF2, regulator of nonsense mediated mRNA decay
increases expression
ISO
deoxynivalenol results in increased expression of UPF2 mRNA
CTD
PMID:31863870
NCBI chr17:77,133,975...77,245,266
Ensembl chr17:77,134,716...77,245,704
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Upf3b
UPF3B, regulator of nonsense mediated mRNA decay
increases expression
ISO
deoxynivalenol results in increased expression of UPF3B mRNA
CTD
PMID:31863870
NCBI chr X:121,200,993...121,219,059
Ensembl chr X:121,200,993...121,218,921
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Uqcrc1
ubiquinol-cytochrome c reductase core protein 1
decreases expression
ISO
deoxynivalenol results in decreased expression of UQCRC1 protein
CTD
PMID:33890134
NCBI chr 8:118,468,223...118,479,968
Ensembl chr 8:118,468,200...118,479,964
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Uqcrfs1
ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
decreases expression
ISO
deoxynivalenol results in decreased expression of UQCRFS1 protein
CTD
PMID:33890134
NCBI chr17:34,173,787...34,190,952
Ensembl chr17:34,173,833...34,190,950
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Usp15
ubiquitin specific peptidase 15
increases expression
ISO
deoxynivalenol results in increased expression of USP15 mRNA
CTD
PMID:22846391
NCBI chr 7:60,643,611...60,805,137
Ensembl chr 7:60,643,613...60,734,099
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Usp24
ubiquitin specific peptidase 24
increases phosphorylation
ISO
deoxynivalenol results in increased phosphorylation of USP24 protein
CTD
PMID:23811945
NCBI chr 5:126,309,396...126,439,147
Ensembl chr 5:126,309,597...126,439,135
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Usp30
ubiquitin specific peptidase 30
increases expression
ISO
deoxynivalenol results in increased expression of USP30 mRNA
CTD
PMID:24247028
NCBI chr12:48,161,905...48,215,878
Ensembl chr12:48,161,908...48,215,968
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Usp36
ubiquitin specific peptidase 36
increases expression
ISO
deoxynivalenol results in increased expression of USP36 protein
CTD
PMID:39638853
NCBI chr10:103,995,970...104,027,492
Ensembl chr10:103,995,970...104,023,450
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Usp39
ubiquitin specific peptidase 39
decreases phosphorylation
ISO
deoxynivalenol results in decreased phosphorylation of USP39 protein
CTD
PMID:23352502
NCBI chr 4:105,932,140...105,964,551
Ensembl chr 4:105,932,140...105,964,551
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Usp7
ubiquitin specific peptidase 7
increases expression
ISO
deoxynivalenol results in increased expression of USP7 protein
CTD
PMID:39638853
NCBI chr10:7,335,508...7,432,018
Ensembl chr10:7,367,604...7,432,013
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Utp14a
UTP14A small subunit processome component
increases expression
ISO
deoxynivalenol results in increased expression of UTP14A protein
CTD
PMID:39638853
NCBI chr X:132,317,163...132,342,524
Ensembl chr X:132,317,159...132,342,523
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Utp15
UTP15, small subunit processome component
increases expression
ISO
deoxynivalenol results in increased expression of UTP15 protein
CTD
PMID:39638853
NCBI chr 2:31,329,222...31,347,022
Ensembl chr 2:31,329,223...31,347,046
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Utp18
UTP18 small subunit processome component
increases expression
ISO
deoxynivalenol results in increased expression of UTP18 protein
CTD
PMID:39638853
NCBI chr10:79,308,785...79,336,241
Ensembl chr10:79,308,787...79,336,197
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Utp20
UTP20 small subunit processome component
increases expression
ISO
deoxynivalenol results in increased expression of UTP20 protein
CTD
PMID:39638853
NCBI chr 7:25,022,029...25,103,024
Ensembl chr 7:25,022,036...25,103,041
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Utp3
UTP3, small subunit processome component
increases expression
ISO
deoxynivalenol results in increased expression of UTP3 mRNA
CTD
PMID:31863870
NCBI chr14:19,799,766...19,801,420
Ensembl chr14:19,796,215...19,801,446
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Utp4
UTP4 small subunit processome component
increases expression
ISO
deoxynivalenol results in increased expression of UTP4 protein
CTD
PMID:39638853
NCBI chr19:51,696,437...51,730,323
Ensembl chr19:51,701,739...51,730,325
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Vamp4
vesicle-associated membrane protein 4
increases expression
ISO
deoxynivalenol results in increased expression of VAMP4 mRNA
CTD
PMID:23792671
NCBI chr13:77,453,135...77,475,909
Ensembl chr13:77,453,121...77,476,024
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Vasn
vasorin
decreases expression
ISO
deoxynivalenol results in decreased expression of VASN protein
CTD
PMID:39638853
NCBI chr10:11,424,174...11,434,681
Ensembl chr10:11,417,327...11,450,704
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Vcan
versican
decreases expression
ISO
deoxynivalenol results in decreased expression of VCAN mRNA
CTD
PMID:31863870
NCBI chr 2:22,497,035...22,595,955
Ensembl chr 2:22,497,035...22,595,955
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Vil1
villin 1
multiple interactions decreases expression
ISO
lauric acid inhibits the reaction [deoxynivalenol results in decreased expression of VIL1 protein]
CTD
PMID:34506767 PMID:39638853
NCBI chr 9:83,440,248...83,467,963
Ensembl chr 9:83,440,248...83,467,961
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Wars1
tryptophanyl-tRNA synthetase 1
decreases expression
ISO
deoxynivalenol results in decreased expression of WARS1 mRNA
CTD
PMID:31863870
NCBI chr 6:133,540,463...133,571,645
Ensembl chr 6:133,539,744...133,571,645
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Washc2c
WASH complex subunit 2C
increases phosphorylation
ISO
deoxynivalenol results in increased phosphorylation of WASHC2 protein
CTD
PMID:23352502
NCBI chr 4:150,912,863...150,998,301
Ensembl chr 4:150,912,395...150,998,301
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Wbp4
WW domain binding protein 4
increases expression
ISO
deoxynivalenol results in increased expression of WBP4 mRNA
CTD
PMID:31863870
NCBI chr15:61,271,774...61,299,740
Ensembl chr15:61,271,783...61,299,740
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Wdr12
WD repeat domain 12
increases expression
ISO
deoxynivalenol results in increased expression of WDR12 protein
CTD
PMID:39638853
NCBI chr 9:68,969,547...68,996,811
Ensembl chr 9:68,969,547...68,996,811
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Wdr20
WD repeat domain 20
increases expression
ISO
deoxynivalenol results in increased expression of WDR20 mRNA
CTD
PMID:31863870
NCBI chr 6:135,572,502...135,642,688
Ensembl chr 6:135,572,893...135,642,688
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Wdr3
WD repeat domain 3
increases expression
ISO
deoxynivalenol results in increased expression of WDR3 protein
CTD
PMID:39638853
NCBI chr 2:190,194,474...190,217,087
Ensembl chr 2:190,194,474...190,217,087
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Wdr36
WD repeat domain 36
increases expression
ISO
deoxynivalenol results in increased expression of WDR36 protein
CTD
PMID:39638853
NCBI chr18:24,747,812...24,783,704
Ensembl chr18:24,747,832...24,783,110
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Wdr43
WD repeat domain 43
increases expression
ISO
deoxynivalenol results in increased expression of WDR43 protein
CTD
PMID:39638853
NCBI chr 6:29,565,610...29,604,954
Ensembl chr 6:29,565,610...29,604,954
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Wdr46
WD repeat domain 46
increases expression
ISO
deoxynivalenol results in increased expression of WDR46 protein
CTD
PMID:39638853
NCBI chr20:4,939,721...4,947,619
Ensembl chr20:4,939,732...4,947,741
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Wdr5
WD repeat domain 5
increases expression
ISO
deoxynivalenol results in increased expression of WDR5 mRNA
CTD
PMID:19438726
NCBI chr 3:31,233,048...31,254,730
Ensembl chr 3:31,235,222...31,254,727
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Wdr74
WD repeat domain 74
increases expression
ISO
deoxynivalenol results in increased expression of WDR74 mRNA; deoxynivalenol results in increased expression of WDR74 protein
CTD
PMID:31863870 PMID:39638853
NCBI chr 1:215,060,901...215,065,687
Ensembl chr 1:215,060,961...215,066,336
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Wdr75
WD repeat domain 75
increases expression
ISO
deoxynivalenol results in increased expression of WDR75 protein
CTD
PMID:39638853
NCBI chr 9:55,395,232...55,425,412
Ensembl chr 9:55,395,222...55,425,412
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Wfdc1
WAP four-disulfide core domain 1
decreases expression
ISO
deoxynivalenol results in decreased expression of WFDC1 mRNA
CTD
PMID:31863870
NCBI chr19:64,628,689...64,647,739
Ensembl chr19:64,607,794...64,648,028
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Wfs1
wolframin ER transmembrane glycoprotein
decreases expression
ISO
deoxynivalenol results in decreased expression of WFS1 protein
CTD
PMID:39638853
NCBI chr14:78,035,205...78,059,718
Ensembl chr14:78,034,864...78,060,459
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Wipi1
WD repeat domain, phosphoinositide interacting 1
decreases expression
ISO
deoxynivalenol results in decreased expression of WIPI1 mRNA
CTD
PMID:31863870
NCBI chr10:95,042,451...95,079,679
Ensembl chr10:95,042,441...95,079,293
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Wrap53
WD repeat containing, antisense to TP53
increases expression
ISO
deoxynivalenol results in increased expression of WRAP53 mRNA
CTD
PMID:31863870
NCBI chr10:54,780,873...54,797,919
Ensembl chr10:54,773,282...54,797,651
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Wwtr1
WW domain containing transcription regulator 1
increases expression
ISO
deoxynivalenol results in increased expression of WWTR1 protein
CTD
PMID:33890134
NCBI chr 2:143,801,181...143,916,941
Ensembl chr 2:143,801,181...143,991,950
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Xbp1
X-box binding protein 1
increases expression increases splicing
ISO
deoxynivalenol results in increased expression of XBP1 protein deoxynivalenol results in increased splicing of XBP1 mRNA
CTD
PMID:19336499
NCBI chr14:84,604,623...84,609,707
Ensembl chr14:84,604,107...84,609,706
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Xrcc1
X-ray repair cross complementing 1
increases expression
ISO
deoxynivalenol results in increased expression of XRCC1 mRNA; deoxynivalenol results in increased expression of XRCC1 protein
CTD
PMID:24355168
NCBI chr 1:89,268,721...89,296,619
Ensembl chr 1:89,268,644...89,296,613
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Yap1
Yes1 associated transcriptional regulator
decreases phosphorylation
ISO
deoxynivalenol results in decreased phosphorylation of YAP1 protein
CTD
PMID:33890134
NCBI chr 8:13,380,551...13,451,640
Ensembl chr 8:13,380,551...13,451,437
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Ybx1
Y box binding protein 1
increases expression
ISO
deoxynivalenol results in increased expression of YBX1 protein
CTD
PMID:39638853
NCBI chr 5:138,167,444...138,188,155
Ensembl chr 5:138,167,444...138,184,188
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Ybx3
Y box binding protein 3
increases expression
ISO
deoxynivalenol results in increased expression of YBX3 protein
CTD
PMID:39638853
NCBI chr 4:166,861,180...166,884,532
Ensembl chr 4:166,861,181...166,884,691
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Zbtb11
zinc finger and BTB domain containing 11
increases expression
ISO
deoxynivalenol results in increased expression of ZBTB11 mRNA
CTD
PMID:31863870
NCBI chr11:58,061,355...58,121,768
Ensembl chr11:58,085,351...58,120,110
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Zbtb18
zinc finger and BTB domain containing 18
increases expression
ISO
deoxynivalenol results in increased expression of ZBTB18 mRNA
CTD
PMID:31863870
NCBI chr13:91,971,602...91,980,058
Ensembl chr13:91,969,755...91,980,386
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Zbtb21
zinc finger and BTB domain containing 21
increases expression
ISO
deoxynivalenol results in increased expression of ZBTB21 mRNA
CTD
PMID:31863870
NCBI chr11:50,781,697...50,796,399
Ensembl chr11:50,781,099...50,796,560
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Zbtb33
zinc finger and BTB domain containing 33
increases expression
ISO
deoxynivalenol results in increased expression of ZBTB33 mRNA
CTD
PMID:31863870
NCBI chr X:121,828,960...121,836,193
Ensembl chr X:121,828,952...121,839,399
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Zc3h11a
zinc finger CCCH-type containing 11A
increases phosphorylation
ISO
deoxynivalenol results in increased phosphorylation of ZC3H11A protein
CTD
PMID:23352502
NCBI chr13:47,625,444...47,665,971
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Zcchc4
zinc finger CCHC-type containing 4
increases expression
ISO
deoxynivalenol results in increased expression of ZCCHC4 mRNA
CTD
PMID:31863870
NCBI chr14:62,378,261...62,419,899
Ensembl chr14:62,378,269...62,419,544
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Zeb1
zinc finger E-box binding homeobox 1
decreases activity multiple interactions
ISO
deoxynivalenol results in decreased activity of ZEB1 protein [Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [deoxynivalenol results in decreased expression of ZEB1 protein]
CTD
PMID:11893416
NCBI chr17:56,644,397...56,811,155
Ensembl chr17:56,644,397...56,810,745
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Zeb2
zinc finger E-box binding homeobox 2
increases expression
ISO
deoxynivalenol results in increased expression of ZEB2 mRNA
CTD
PMID:26763390
NCBI chr 3:49,624,028...49,754,323
Ensembl chr 3:49,624,028...49,754,323
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Zfp354c
zinc finger protein 354C
decreases expression
ISO
deoxynivalenol results in decreased expression of ZNF354C protein
CTD
PMID:33890134
NCBI chr10:35,630,738...35,647,176
Ensembl chr10:35,630,738...35,646,754
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Zfp777
zinc finger protein 777
increases expression
ISO
deoxynivalenol results in increased expression of ZNF777 mRNA
CTD
PMID:31863870
NCBI chr 4:78,347,315...78,377,720
Ensembl chr 4:78,347,315...78,373,357
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Zfr
zinc finger RNA binding protein
increases expression
ISO
deoxynivalenol results in increased expression of ZFR protein
CTD
PMID:39638853
NCBI chr 2:62,864,333...62,927,377
Ensembl chr 2:62,864,338...62,929,133
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Zranb2
zinc finger RANBP2-type containing 2
increases expression
ISO
deoxynivalenol results in increased expression of ZRANB2 protein
CTD
PMID:39638853
NCBI chr 2:249,232,010...249,245,786
Ensembl chr 2:249,232,010...249,245,780
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Il1b
interleukin 1 beta
increases expression
ISO
deoxynivalenol-3-glucoside results in increased expression of IL1B mRNA
CTD
PMID:24793808
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
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Il6
interleukin 6
increases expression
ISO
deoxynivalenol-3-glucoside results in increased expression of IL6 mRNA
CTD
PMID:24793808
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
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Arc
activity-regulated cytoskeleton-associated protein
decreases expression
ISO
diacetoxyscirpenol results in decreased expression of ARC mRNA
CTD
PMID:31836554
NCBI chr 7:108,444,959...108,448,413
Ensembl chr 7:108,444,692...108,451,220
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Casp12
caspase 12
decreases expression
ISO
diacetoxyscirpenol results in decreased expression of CASP12 mRNA
CTD
PMID:31836554
NCBI chr 8:10,927,188...10,954,442
Ensembl chr 8:10,926,994...10,954,442
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Casp9
caspase 9
decreases expression
ISO
diacetoxyscirpenol results in decreased expression of CASP9 mRNA
CTD
PMID:31836554
Ensembl chr 5:159,391,188...159,409,648
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Ccnb1
cyclin B1
decreases expression
ISO
diacetoxyscirpenol results in decreased expression of CCNB1 mRNA
CTD
PMID:31836554
NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:33,646,252...33,655,225
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Cdk4
cyclin-dependent kinase 4
decreases expression
ISO
diacetoxyscirpenol results in decreased expression of CDK4 mRNA
CTD
PMID:31836554
NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:64,771,147...64,775,163
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Cdkn2a
cyclin-dependent kinase inhibitor 2A
decreases expression
ISO
diacetoxyscirpenol results in decreased expression of CDKN2A mRNA
CTD
PMID:31836554
NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:109,100,772...109,119,248
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Chrna7
cholinergic receptor nicotinic alpha 7 subunit
decreases expression
ISO
diacetoxyscirpenol results in decreased expression of CHRNA7 mRNA
CTD
PMID:31836554
NCBI chr 1:116,711,559...116,837,269
Ensembl chr 1:126,123,425...126,446,858
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Gip
gastric inhibitory polypeptide
multiple interactions
ISO
diacetoxyscirpenol results in increased expression of and results in increased secretion of GIP protein
CTD
PMID:28666375
NCBI chr10:81,465,070...81,473,216
Ensembl chr10:81,465,062...81,473,216
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Gria1
glutamate ionotropic receptor AMPA type subunit 1
increases expression
ISO
diacetoxyscirpenol results in increased expression of GRIA1 mRNA
CTD
PMID:31836554
NCBI chr10:41,710,540...42,030,105
Ensembl chr10:41,711,080...42,030,309
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Gria2
glutamate ionotropic receptor AMPA type subunit 2
increases expression
ISO
diacetoxyscirpenol results in increased expression of GRIA2 mRNA
CTD
PMID:31836554
NCBI chr 2:168,247,490...168,367,616
Ensembl chr 2:168,247,496...168,367,616
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Gria3
glutamate ionotropic receptor AMPA type subunit 3
decreases expression
ISO
diacetoxyscirpenol results in decreased expression of GRIA3 mRNA
CTD
PMID:31836554
NCBI chr X:125,103,975...125,369,690
Ensembl chr X:125,103,782...125,369,679
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Grin2a
glutamate ionotropic receptor NMDA type subunit 2A
decreases expression
ISO
diacetoxyscirpenol results in decreased expression of GRIN2A mRNA
CTD
PMID:31836554
NCBI chr10:6,136,458...6,560,003
Ensembl chr10:6,138,037...6,551,378
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Itsn1
intersectin 1
increases expression
ISO
diacetoxyscirpenol results in increased expression of ITSN1 mRNA
CTD
PMID:31836554
NCBI chr11:30,978,590...31,160,645
Ensembl chr11:44,513,186...44,646,598
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Kit
KIT proto-oncogene receptor tyrosine kinase
decreases expression
ISO
diacetoxyscirpenol results in decreased expression of KIT mRNA
CTD
PMID:31836554
NCBI chr14:32,901,615...32,978,895
Ensembl chr14:32,903,033...32,978,812
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Ogg1
8-oxoguanine DNA glycosylase
decreases expression
ISO
diacetoxyscirpenol results in decreased expression of OGG1 mRNA
CTD
PMID:31836554
NCBI chr 4:148,030,237...148,037,599
Ensembl chr 4:148,030,349...148,037,604
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Parp1
poly (ADP-ribose) polymerase 1
decreases expression
ISO
diacetoxyscirpenol results in decreased expression of PARP1 mRNA
CTD
PMID:31836554
NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567
G
Ptgs2
prostaglandin-endoperoxide synthase 2
decreases expression
ISO
diacetoxyscirpenol results in decreased expression of PTGS2 mRNA
CTD
PMID:31836554
NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
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Rb1
RB transcriptional corepressor 1
decreases expression
ISO
diacetoxyscirpenol results in decreased expression of RB1 mRNA
CTD
PMID:31836554
NCBI chr15:54,780,858...54,911,989
Ensembl chr15:54,780,858...54,911,857
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Slc17a6
solute carrier family 17 member 6
increases expression
ISO
diacetoxyscirpenol results in increased expression of SLC17A6 mRNA
CTD
PMID:31836554
NCBI chr 1:110,348,447...110,388,499
Ensembl chr 1:110,348,447...110,388,498
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Slc17a7
solute carrier family 17 member 7
decreases expression
ISO
diacetoxyscirpenol results in decreased expression of SLC17A7 mRNA
CTD
PMID:31836554
NCBI chr 1:104,786,172...104,798,049
Ensembl chr 1:104,785,955...104,798,049
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Tp53
tumor protein p53
decreases expression
ISO
diacetoxyscirpenol results in decreased expression of TRP53 mRNA
CTD
PMID:31836554
NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
G
Ar
androgen receptor
decreases activity
ISO
fusarenon-X results in decreased activity of AR protein
CTD
PMID:27481073
NCBI chr X:67,135,317...67,304,476
Ensembl chr X:67,135,317...67,304,467
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Atf6
activating transcription factor 6
increases expression
ISO
fusarenon-X results in increased expression of ATF6 mRNA
CTD
PMID:20682335
NCBI chr13:85,460,312...85,639,959
Ensembl chr13:85,462,840...85,640,033
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Bad
BCL2-associated agonist of cell death
increases expression
ISO
fusarenon-X results in increased expression of BAD mRNA
CTD
PMID:24983900
NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:213,562,187...213,572,034
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Bax
BCL2 associated X, apoptosis regulator
increases expression
ISO
fusarenon-X results in increased expression of BAX mRNA
CTD
PMID:24983900
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
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Bcl2
BCL2, apoptosis regulator
increases expression decreases expression
ISO
fusarenon-X results in increased expression of BCL2 mRNA fusarenon-X results in decreased expression of BCL2 mRNA
CTD
PMID:24983900
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
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Bcl2a1
BCL2-related protein A1
increases expression
ISO
fusarenon-X results in increased expression of BCL2A1B mRNA
CTD
PMID:24983900
NCBI chr 8:98,596,806...98,604,890
Ensembl chr 8:98,596,650...98,604,890
G
Bcl2l1
Bcl2-like 1
increases expression
ISO
fusarenon-X results in increased expression of BCL2L1 mRNA
CTD
PMID:24983900
NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907 Ensembl chr 1:161,745,540...161,764,907
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Bcl2l2
Bcl2-like 2
increases expression
ISO
fusarenon-X results in increased expression of BCL2L2 mRNA
CTD
PMID:24983900
NCBI chr15:32,326,686...32,337,834
Ensembl chr15:32,326,020...32,335,379
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Bid
BH3 interacting domain death agonist
decreases expression
ISO
fusarenon-X results in decreased expression of BID mRNA
CTD
PMID:24983900
NCBI chr 4:155,785,366...155,808,775
Ensembl chr 4:155,785,377...155,808,275
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Casp4
caspase 4
increases expression
ISO
fusarenon-X results in increased expression of CASP4 mRNA
CTD
PMID:24983900
NCBI chr 8:10,883,817...10,919,978
Ensembl chr 8:10,883,769...10,920,727
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Casp8
caspase 8
increases expression
ISO
fusarenon-X results in increased expression of CASP8 mRNA
CTD
PMID:24983900
NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699
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Casp9
caspase 9
increases expression
ISO
fusarenon-X results in increased expression of CASP9 mRNA
CTD
PMID:24983900
Ensembl chr 5:159,391,188...159,409,648
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Cck
cholecystokinin
increases expression
ISO
fusarenon-X results in increased expression of CCK protein
CTD
PMID:24385417
NCBI chr 8:130,031,012...130,037,702
Ensembl chr 8:130,031,013...130,037,686
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Ccl2
C-C motif chemokine ligand 2
increases expression
ISO
fusarenon-X results in increased expression of CCL2 mRNA
CTD
PMID:24793808
NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875
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Ccl7
C-C motif chemokine ligand 7
increases expression
ISO
fusarenon-X results in increased expression of CCL7 mRNA
CTD
PMID:24793808
NCBI chr10:67,514,095...67,515,945
Ensembl chr10:67,514,091...67,515,947
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Cd40lg
CD40 ligand
decreases expression
ISO
fusarenon-X results in decreased expression of CD40LG mRNA
CTD
PMID:24983900
NCBI chr X:140,164,341...140,176,057
Ensembl chr X:140,164,302...140,176,475
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Cxcl2
C-X-C motif chemokine ligand 2
increases expression
ISO
fusarenon-X results in increased expression of CXCL2 mRNA
CTD
PMID:24793808
NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,465,242...17,467,255
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Eif2a
eukaryotic translation initiation factor 2A
increases phosphorylation
ISO
fusarenon-X results in increased phosphorylation of EIF2A protein
CTD
PMID:20682335
NCBI chr 2:144,911,247...144,944,705
Ensembl chr 2:144,911,153...144,945,201
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Fas
Fas cell surface death receptor
increases expression
ISO
fusarenon-X results in increased expression of FAS mRNA
CTD
PMID:24983900
NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:241,205,935...241,246,104
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Faslg
Fas ligand
decreases expression
ISO
fusarenon-X results in decreased expression of FASL mRNA
CTD
PMID:24983900
NCBI chr13:76,680,885...76,706,042
Ensembl chr13:76,688,243...76,695,503
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Gzmb
granzyme B
increases expression
ISO
fusarenon-X results in increased expression of GZMB mRNA
CTD
PMID:24983900
NCBI chr15:34,459,007...34,462,469
Ensembl chr15:34,459,007...34,462,469
G
Hspa5
heat shock protein family A (Hsp70) member 5
decreases expression
ISO
fusarenon-X results in decreased expression of HSPA5 mRNA
CTD
PMID:20682335
NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790
G
Il1b
interleukin 1 beta
increases expression
ISO
fusarenon-X results in increased expression of IL1B mRNA
CTD
PMID:24793808
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
G
Il6
interleukin 6
increases expression
ISO
fusarenon-X results in increased expression of IL6 mRNA
CTD
PMID:24793808
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
G
Irf2
interferon regulatory factor 2
increases expression
ISO
fusarenon-X results in increased expression of IRF2 mRNA
CTD
PMID:24983900
NCBI chr16:45,439,215...45,550,054
Ensembl chr16:52,164,442...52,282,627
G
Map3k14
mitogen-activated protein kinase kinase kinase 14
increases expression
ISO
fusarenon-X results in increased expression of MAP3K14 mRNA
CTD
PMID:24983900
NCBI chr10:88,665,417...88,715,669
Ensembl chr10:88,665,417...88,715,592
G
Nfkbie
NFKB inhibitor epsilon
increases expression
ISO
fusarenon-X results in increased expression of NFKBIE mRNA
CTD
PMID:24983900
NCBI chr 9:22,941,037...22,947,872
Ensembl chr 9:22,941,040...22,947,872
G
Ngf
nerve growth factor
increases expression
ISO
fusarenon-X results in increased expression of NGF mRNA
CTD
PMID:24983900
NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:192,589,582...192,643,834
G
Ngfr
nerve growth factor receptor
decreases expression
ISO
fusarenon-X results in decreased expression of NGFR mRNA
CTD
PMID:24983900
NCBI chr10:81,012,077...81,030,305
Ensembl chr10:81,012,089...81,030,305
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Nr3c1
nuclear receptor subfamily 3, group C, member 1
decreases expression
ISO
fusarenon-X results in decreased expression of NR3C1 mRNA
CTD
PMID:24983900
NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,522,783...31,643,843
G
Pparg
peroxisome proliferator-activated receptor gamma
decreases activity
ISO
fusarenon-X results in decreased activity of PPARG protein
CTD
PMID:27481073
NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104
G
Ptgs2
prostaglandin-endoperoxide synthase 2
increases expression
ISO
fusarenon-X results in increased expression of PTGS2 mRNA
CTD
PMID:14514436
NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
G
Tnf
tumor necrosis factor
increases expression
ISO
fusarenon-X results in increased expression of TNF mRNA
CTD
PMID:24793808 PMID:24983900
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
G
Tnfrsf10b
TNF receptor superfamily member 10b
decreases expression
ISO
fusarenon-X results in decreased expression of TNFRSF10B mRNA
CTD
PMID:24983900
NCBI chr15:51,249,883...51,278,091
Ensembl chr15:51,250,112...51,278,082
G
Tnfrsf1b
TNF receptor superfamily member 1B
increases expression
ISO
fusarenon-X results in increased expression of TNFRSF1B mRNA
CTD
PMID:24983900
NCBI chr 5:162,356,250...162,387,411
Ensembl chr 5:162,353,848...162,387,411
G
Tnfsf10
TNF superfamily member 10
increases expression
ISO
fusarenon-X results in increased expression of TNFSF10 mRNA
CTD
PMID:24983900
NCBI chr 2:112,136,550...112,155,903
G
Tp53
tumor protein p53
increases expression
ISO
fusarenon-X results in increased expression of TRP53 mRNA
CTD
PMID:24983900
NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
G
Tp63
tumor protein p63
decreases expression
ISO
fusarenon-X results in decreased expression of TRP63 mRNA
CTD
PMID:24983900
NCBI chr11:88,343,647...88,554,543
Ensembl chr11:88,343,651...88,554,177
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Tp73
tumor protein p73
increases expression
ISO
fusarenon-X results in increased expression of TRP73 mRNA
CTD
PMID:24983900
NCBI chr 5:169,903,801...169,988,075
Ensembl chr 5:169,903,801...169,963,552
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Traf1
TNF receptor-associated factor 1
increases expression
ISO
fusarenon-X results in increased expression of TRAF1 mRNA
CTD
PMID:24983900
NCBI chr 3:38,607,707...38,639,641
Ensembl chr 3:38,619,506...38,636,264
G
Traf3
Tnf receptor-associated factor 3
decreases expression
ISO
fusarenon-X results in decreased expression of TRAF3 mRNA
CTD
PMID:24983900
NCBI chr 6:136,025,097...136,128,363
Ensembl chr 6:136,027,157...136,128,363
G
Traf6
TNF receptor associated factor 6
increases expression
ISO
fusarenon-X results in increased expression of TRAF6 mRNA
CTD
PMID:24983900
NCBI chr 3:108,418,537...108,443,330
Ensembl chr 3:108,418,513...108,443,328
G
Xiap
X-linked inhibitor of apoptosis
decreases expression
ISO
fusarenon-X results in decreased expression of XIAP mRNA
CTD
PMID:24983900
NCBI chr X:125,756,107...125,803,979
Ensembl chr X:125,737,971...125,803,978
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Acan
aggrecan
decreases expression increases cleavage
ISO
HT-2 toxin results in decreased expression of ACAN mRNA HT-2 toxin results in increased cleavage of ACAN protein
CTD
PMID:38734200
NCBI chr 1:142,390,951...142,453,779
Ensembl chr 1:142,390,951...142,453,779
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Adamts5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
increases expression
ISO
HT-2 toxin results in increased expression of ADAMTS5 mRNA; HT-2 toxin results in increased expression of ADAMTS5 protein
CTD
PMID:38734200
NCBI chr11:38,486,945...38,533,516
Ensembl chr11:38,486,955...38,533,516
G
Casp3
caspase 3
increases activity
ISO
HT-2 toxin results in increased activity of CASP3 protein
CTD
PMID:19428930
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
G
Col2a1
collagen type II alpha 1 chain
decreases expression
ISO
HT-2 toxin results in decreased expression of COL2A1 mRNA; HT-2 toxin results in decreased expression of COL2A1 protein
CTD
PMID:38734200
NCBI chr 7:130,977,561...131,006,627
Ensembl chr 7:130,977,561...131,006,627
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Comp
cartilage oligomeric matrix protein
decreases expression
ISO
HT-2 toxin results in decreased expression of COMP mRNA
CTD
PMID:38734200
NCBI chr16:19,081,172...19,089,548
Ensembl chr16:19,081,172...19,089,605
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Cyp11a1
cytochrome P450, family 11, subfamily a, polypeptide 1
decreases expression
ISO
HT-2 toxin results in decreased expression of CYP11A mRNA
CTD
PMID:22982764
NCBI chr 8:67,318,665...67,330,196
Ensembl chr 8:67,270,556...67,330,196
G
Cyp17a1
cytochrome P450, family 17, subfamily a, polypeptide 1
decreases expression
ISO
HT-2 toxin results in decreased expression of CYP17A1 mRNA
CTD
PMID:22982764
NCBI chr 1:255,476,861...255,484,547
Ensembl chr 1:255,476,861...255,482,974
G
Cyp19a1
cytochrome P450, family 19, subfamily a, polypeptide 1
decreases expression
ISO
HT-2 toxin results in decreased expression of CYP19A1 mRNA
CTD
PMID:22982764
NCBI chr 8:63,449,148...63,476,534
Ensembl chr 8:63,449,148...63,476,917
G
Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
increases expression
ISO
HT-2 toxin results in increased expression of CYP1A1 mRNA
CTD
PMID:22982764
NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
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Ephx1
epoxide hydrolase 1
increases expression
ISO
HT-2 toxin results in increased expression of EPHX1 mRNA
CTD
PMID:22982764
NCBI chr13:95,246,079...95,275,852
Ensembl chr13:95,246,080...95,321,981
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Gip
gastric inhibitory polypeptide
multiple interactions
ISO
HT-2 toxin results in increased expression of and results in increased secretion of GIP protein
CTD
PMID:28666375
NCBI chr10:81,465,070...81,473,216
Ensembl chr10:81,465,062...81,473,216
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Hes1
hes family bHLH transcription factor 1
increases expression
ISO
HT-2 toxin results in increased expression of HES1 mRNA; HT-2 toxin results in increased expression of HES1 protein
CTD
PMID:38734200
NCBI chr11:84,210,632...84,213,045
Ensembl chr11:84,210,633...84,213,061
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Hmgcr
3-hydroxy-3-methylglutaryl-CoA reductase
decreases expression
ISO
HT-2 toxin results in decreased expression of HMGCR mRNA
CTD
PMID:22982764
NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:29,720,553...29,754,533
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Hsd17b1
hydroxysteroid (17-beta) dehydrogenase 1
increases expression
ISO
HT-2 toxin results in increased expression of HSD17B1 mRNA
CTD
PMID:22982764
NCBI chr10:86,510,011...86,512,211
Ensembl chr10:86,510,011...86,512,210
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Jag1
jagged canonical Notch ligand 1
increases expression
ISO
HT-2 toxin results in increased expression of JAG1 mRNA
CTD
PMID:38734200
NCBI chr 3:144,859,453...144,894,883
Ensembl chr 3:144,859,453...144,894,872
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Maml1
mastermind-like transcriptional coactivator 1
increases expression
ISO
HT-2 toxin results in increased expression of MAML1 mRNA
CTD
PMID:38734200
NCBI chr10:35,089,715...35,124,100
Ensembl chr10:35,089,715...35,124,100
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Notch1
notch receptor 1
increases expression
ISO
HT-2 toxin results in increased expression of NOTCH1 mRNA; HT-2 toxin results in increased expression of NOTCH1 protein
CTD
PMID:38734200
NCBI chr 3:29,676,040...29,721,613
Ensembl chr 3:29,676,171...29,721,613
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Rbpj
recombination signal binding protein for immunoglobulin kappa J region
increases expression
ISO
HT-2 toxin results in increased expression of RBPJ mRNA
CTD
PMID:38734200
NCBI chr14:61,551,366...61,736,220
Ensembl chr14:61,551,366...61,736,307
G
Casp3
caspase 3
increases activity
ISO
neosolaniol results in increased activity of CASP3 protein
CTD
PMID:19428930
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
G
Gip
gastric inhibitory polypeptide
multiple interactions
ISO
neosolaniol results in increased expression of and results in increased secretion of GIP protein
CTD
PMID:28666375
NCBI chr10:81,465,070...81,473,216
Ensembl chr10:81,465,062...81,473,216
G
A2m
alpha-2-macroglobulin
decreases expression
ISO
nivalenol results in decreased expression of A2M protein
CTD
PMID:39638853
NCBI chr 4:156,570,163...156,619,870
Ensembl chr 4:156,569,860...156,619,868
G
Aass
aminoadipate-semialdehyde synthase
decreases expression
ISO
nivalenol results in decreased expression of AASS protein
CTD
PMID:39638853
NCBI chr 4:52,572,146...52,628,811
Ensembl chr 4:52,572,147...52,657,600
G
Abcb1a
ATP binding cassette subfamily B member 1A
increases expression
ISO
nivalenol results in increased expression of ABCB1 protein
CTD
PMID:39638853
NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135
G
Acly
ATP citrate lyase
decreases expression
ISO
nivalenol results in decreased expression of ACLY protein
CTD
PMID:39638853
NCBI chr10:85,912,402...85,964,605
Ensembl chr10:85,912,402...85,963,631
G
Acot1
acyl-CoA thioesterase 1
decreases expression
ISO
nivalenol results in decreased expression of ACOT1 protein
CTD
PMID:39638853
NCBI chr 6:109,367,274...109,375,268
Ensembl chr 6:109,367,268...109,380,749
G
Afp
alpha-fetoprotein
decreases expression
ISO
nivalenol results in decreased expression of AFP protein
CTD
PMID:39638853
NCBI chr14:17,857,584...17,875,645
Ensembl chr14:17,857,584...17,875,649
G
Agrn
agrin
decreases expression
ISO
nivalenol results in decreased expression of AGRN protein
CTD
PMID:39638853
NCBI chr 5:172,031,528...172,064,429
Ensembl chr 5:172,031,528...172,064,539
G
Agt
angiotensinogen
decreases expression
ISO
nivalenol results in decreased expression of AGT protein
CTD
PMID:39638853
NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944
G
Aldh1a1
aldehyde dehydrogenase 1 family, member A1
decreases expression
ISO
nivalenol results in decreased expression of ALDH1A1 protein
CTD
PMID:39638853
NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:227,427,070...227,579,500
G
Ambp
alpha-1-microglobulin/bikunin precursor
decreases expression
ISO
nivalenol results in decreased expression of AMBP protein
CTD
PMID:39638853
NCBI chr 5:81,583,621...81,593,938
Ensembl chr 5:81,583,622...81,593,850
G
Aplp2
amyloid beta precursor like protein 2
decreases expression
ISO
nivalenol results in decreased expression of APLP2 protein
CTD
PMID:39638853
NCBI chr 8:37,857,407...37,920,487
Ensembl chr 8:37,857,407...37,920,031
G
Apoa1
apolipoprotein A1
decreases expression
ISO
nivalenol results in decreased expression of APOA1 protein
CTD
PMID:39638853
NCBI chr 8:55,423,945...55,425,729
Ensembl chr 8:55,423,825...55,425,729
G
Apob
apolipoprotein B
decreases expression
ISO
nivalenol results in decreased expression of APOB protein
CTD
PMID:39638853
NCBI chr 6:36,563,704...36,603,300
Ensembl chr 6:36,563,704...36,611,814
G
Apoe
apolipoprotein E
decreases expression
ISO
nivalenol results in decreased expression of APOE protein
CTD
PMID:39638853
NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:88,481,385...88,485,855
G
Ar
androgen receptor
decreases activity
ISO
nivalenol results in decreased activity of AR protein
CTD
PMID:27481073
NCBI chr X:67,135,317...67,304,476
Ensembl chr X:67,135,317...67,304,467
G
Asns
asparagine synthetase (glutamine-hydrolyzing)
decreases expression
ISO
nivalenol results in decreased expression of ASNS protein
CTD
PMID:39638853
NCBI chr 4:36,752,061...36,769,970
Ensembl chr 4:36,751,802...36,776,050
G
Atf3
activating transcription factor 3
increases expression
ISO
nivalenol results in increased expression of ATF3 mRNA
CTD
PMID:19101521
NCBI chr13:105,274,103...105,331,653
Ensembl chr13:105,282,440...105,295,750
G
Atf6
activating transcription factor 6
increases expression
ISO
nivalenol results in increased expression of ATF6 mRNA
CTD
PMID:20682335
NCBI chr13:85,460,312...85,639,959
Ensembl chr13:85,462,840...85,640,033
G
Atp5f1a
ATP synthase F1 subunit alpha
decreases expression
ISO
nivalenol results in decreased expression of ATP5F1A mRNA
CTD
PMID:35016910
NCBI chr18:73,567,537...73,575,473
Ensembl chr18:73,567,526...73,575,922
G
Atp6ap2
ATPase H+ transporting accessory protein 2
increases expression decreases expression
ISO
nivalenol results in increased expression of ATP6AP2 mRNA nivalenol results in decreased expression of ATP6AP2 protein
CTD
PMID:35016910 PMID:39638853
NCBI chr X:12,856,708...12,883,670
Ensembl chr X:12,855,859...12,905,875
G
Aurka
aurora kinase A
increases expression
ISO
nivalenol results in increased expression of AURKA protein
CTD
PMID:39638853
NCBI chr 3:181,546,742...181,562,890
Ensembl chr 3:181,546,742...181,562,771
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B2m
beta-2 microglobulin
decreases expression
ISO
nivalenol results in decreased expression of B2M protein
CTD
PMID:39638853
NCBI chr 3:129,549,236...129,555,354
Ensembl chr 3:129,549,318...129,555,356
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B4gat1
beta-1,4-glucuronyltransferase 1
decreases expression
ISO
nivalenol results in decreased expression of B4GAT1 protein
CTD
PMID:39638853
NCBI chr 1:211,772,644...211,774,866
Ensembl chr 1:211,772,606...211,775,442
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Bax
BCL2 associated X, apoptosis regulator
increases expression
ISO
nivalenol results in increased expression of BAX protein
CTD
PMID:19410639
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
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Bcat2
branched chain amino acid transaminase 2
decreases expression
ISO
nivalenol results in decreased expression of BCAT2 mRNA
CTD
PMID:35016910
NCBI chr 1:105,175,157...105,196,474
Ensembl chr 1:105,176,977...105,196,463
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Bet1
Bet1 golgi vesicular membrane trafficking protein
decreases expression
ISO
nivalenol results in decreased expression of BET1 mRNA
CTD
PMID:35016910
NCBI chr 4:33,070,892...33,081,162
Ensembl chr 4:33,070,891...33,081,164
G
Bms1
BMS1 ribosome biogenesis factor
decreases expression
ISO
nivalenol results in decreased expression of BMS1 mRNA
CTD
PMID:35016910
NCBI chr 4:153,230,471...153,267,437
Ensembl chr 4:153,230,471...153,267,429
G
C3
complement C3
decreases expression
ISO
nivalenol results in decreased expression of C3 protein
CTD
PMID:39638853
NCBI chr 9:2,174,412...2,201,339
Ensembl chr 9:2,174,412...2,201,339
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C4a
complement C4A
decreases expression
ISO
nivalenol results in decreased expression of C4A protein
CTD
PMID:39638853
NCBI chr20:4,010,306...4,024,707
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Cadm1
cell adhesion molecule 1
decreases expression
ISO
nivalenol results in decreased expression of CADM1 protein
CTD
PMID:39638853
NCBI chr 8:56,744,374...57,075,264
Ensembl chr 8:56,744,372...57,080,192
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Caprin1
cell cycle associated protein 1
increases expression
ISO
nivalenol results in increased expression of CAPRIN1 protein
CTD
PMID:39638853
NCBI chr 3:110,606,489...110,685,408
Ensembl chr 3:110,606,489...110,685,562
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Casp3
caspase 3
increases cleavage
ISO
nivalenol results in increased cleavage of CASP3 protein
CTD
PMID:19410639
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
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Cck
cholecystokinin
increases expression
ISO
nivalenol results in increased expression of CCK protein
CTD
PMID:24385417
NCBI chr 8:130,031,012...130,037,702
Ensembl chr 8:130,031,013...130,037,686
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Ccl2
C-C motif chemokine ligand 2
increases expression
ISO
nivalenol results in increased expression of CCL2 mRNA
CTD
PMID:24793808
NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875
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Cdkn2aip
CDKN2A interacting protein
increases expression
ISO
nivalenol results in increased expression of CDKN2AIP protein
CTD
PMID:39638853
NCBI chr16:51,266,613...51,274,051
Ensembl chr16:51,268,896...51,274,049
G
Celf1
CUGBP, Elav-like family member 1
increases expression
ISO
nivalenol results in increased expression of CELF1 protein
CTD
PMID:39638853
NCBI chr 3:97,380,407...97,455,253
Ensembl chr 3:97,380,424...97,452,791
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Chchd1
coiled-coil-helix-coiled-coil-helix domain containing 1
decreases expression
ISO
nivalenol results in decreased expression of CHCHD1 protein
CTD
PMID:39638853
NCBI chr15:3,641,973...3,643,155
Ensembl chr15:3,641,981...3,643,155
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Cherp
calcium homeostasis endoplasmic reticulum protein
increases expression
ISO
nivalenol results in increased expression of CHERP mRNA nivalenol results in increased expression of CHERP protein
CTD
PMID:35016910 PMID:39638853
NCBI chr16:17,401,497...17,414,549
Ensembl chr16:17,401,497...17,414,549
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Clic4
chloride intracellular channel 4
decreases expression
ISO
nivalenol results in decreased expression of CLIC4 mRNA
CTD
PMID:35016910
NCBI chr 5:152,737,371...152,797,118
Ensembl chr 5:152,737,371...152,797,118
G
Cluh
clustered mitochondria homolog
increases expression
ISO
nivalenol results in increased expression of CLUH mRNA
CTD
PMID:35016910
NCBI chr10:59,509,580...59,531,345
Ensembl chr10:60,008,119...60,029,742
G
Cnih1
cornichon family member 1
decreases expression
ISO
nivalenol results in decreased expression of CNIH1 protein
CTD
PMID:39638853
NCBI chr15:22,517,755...22,529,651
Ensembl chr15:22,497,340...22,529,578
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Cnpy2
canopy FGF signaling regulator 2
increases expression
ISO
nivalenol results in increased expression of CNPY2 protein
CTD
PMID:39638853
NCBI chr 7:1,332,293...1,338,081
Ensembl chr 7:1,334,335...1,340,333
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Coa7
cytochrome c oxidase assembly factor 7
increases expression
ISO
nivalenol results in increased expression of COA7 protein
CTD
PMID:39638853
NCBI chr 5:128,298,084...128,308,935
Ensembl chr 5:128,298,093...128,309,664
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Cog3
component of oligomeric golgi complex 3
increases expression
ISO
nivalenol results in increased expression of COG3 mRNA
CTD
PMID:35016910
NCBI chr15:57,389,994...57,480,454
Ensembl chr15:57,390,238...57,480,097
G
Col18a1
collagen type XVIII alpha 1 chain
decreases expression
ISO
nivalenol results in decreased expression of COL18A1 protein
CTD
PMID:39638853
NCBI chr20:11,473,645...11,582,111
Ensembl chr20:11,473,645...11,582,112
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Cox19
cytochrome c oxidase assembly factor COX19
increases expression
ISO
nivalenol results in increased expression of COX19 protein
CTD
PMID:39638853
NCBI chr12:15,303,535...15,313,014
Ensembl chr12:20,417,341...20,426,868
G
Cpd
carboxypeptidase D
decreases expression
ISO
nivalenol results in decreased expression of CPD protein
CTD
PMID:39638853
NCBI chr10:62,121,681...62,185,638
Ensembl chr10:62,121,679...62,185,638
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Csde1
cold shock domain containing E1
increases expression
ISO
nivalenol results in increased expression of CSDE1 protein
CTD
PMID:39638853
NCBI chr 2:193,234,546...193,271,301
Ensembl chr 2:193,243,526...193,271,301
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Cxcl2
C-X-C motif chemokine ligand 2
increases expression
ISO
nivalenol results in increased expression of CXCL2 mRNA
CTD
PMID:24793808
NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,465,242...17,467,255
G
Cyp27a1
cytochrome P450, family 27, subfamily a, polypeptide 1
decreases expression
ISO
nivalenol results in decreased expression of CYP27A1 protein
CTD
PMID:39638853
NCBI chr 9:83,712,402...83,743,222
Ensembl chr 9:83,713,293...83,743,215
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Dcaf13
DDB1 and CUL4 associated factor 13
increases expression
ISO
nivalenol results in increased expression of DCAF13 protein
CTD
PMID:39638853
NCBI chr 7:72,045,828...72,081,039
Ensembl chr 7:72,045,872...72,083,629
G
Ddx18
DEAD-box helicase 18
increases expression
ISO
nivalenol results in increased expression of DDX18 protein
CTD
PMID:39638853
NCBI chr13:35,282,391...35,296,038
Ensembl chr13:35,282,467...35,295,972
G
Ddx21
DExD-box helicase 21
increases expression
ISO
nivalenol results in increased expression of DDX21 protein
CTD
PMID:39638853
NCBI chr20:31,077,044...31,097,238
Ensembl chr20:31,077,045...31,097,238
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Ddx24
DEAD-box helicase 24
increases expression
ISO
nivalenol results in increased expression of DDX24 protein
CTD
PMID:39638853
NCBI chr 6:128,329,554...128,346,818
Ensembl chr 6:128,329,554...128,349,625
G
Ddx27
DEAD-box helicase 27
increases expression
ISO
nivalenol results in increased expression of DDX27 protein
CTD
PMID:39638853
NCBI chr 3:176,163,220...176,182,418
Ensembl chr 3:176,163,203...176,182,410
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Ddx54
DEAD-box helicase 54
increases expression
ISO
nivalenol results in increased expression of DDX54 protein
CTD
PMID:39638853
NCBI chr12:41,595,298...41,610,560
Ensembl chr12:41,595,555...41,611,053
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Ddx56
DEAD-box helicase 56
increases expression
ISO
nivalenol results in increased expression of DDX56 protein
CTD
PMID:39638853
NCBI chr14:85,325,942...85,336,262
Ensembl chr14:85,325,942...85,336,262
G
Ddx6
DEAD-box helicase 6
increases expression
ISO
nivalenol results in increased expression of DDX6 protein
CTD
PMID:39638853
NCBI chr 8:53,827,661...53,864,538
Ensembl chr 8:53,827,835...53,860,977
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Dhx37
DEAH-box helicase 37
increases expression
ISO
nivalenol results in increased expression of DHX37 protein
CTD
PMID:39638853
NCBI chr12:36,856,119...36,876,245
Ensembl chr12:36,849,701...36,876,240
G
Dkc1
dyskerin pseudouridine synthase 1
increases expression
ISO
nivalenol results in increased expression of DKC1 protein
CTD
PMID:39638853
NCBI chr X:157,751,651...157,757,796
Ensembl chr Y:380,743...385,405 Ensembl chr X:380,743...385,405
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Dnttip2
deoxynucleotidyltransferase, terminal, interacting protein 2
increases expression
ISO
nivalenol results in increased expression of DNTTIP2 protein
CTD
PMID:39638853
NCBI chr 2:213,058,975...213,071,020
Ensembl chr 2:213,058,962...213,071,016
G
Ech1
enoyl-CoA hydratase 1
decreases expression
ISO
nivalenol results in decreased expression of ECH1 protein
CTD
PMID:39638853
NCBI chr 1:93,241,076...93,248,314
Ensembl chr 1:93,241,734...93,248,440
G
Eea1
early endosome antigen 1
increases expression
ISO
nivalenol results in increased expression of EEA1 protein
CTD
PMID:39638853
NCBI chr 7:32,441,281...32,608,808
Ensembl chr 7:32,441,272...32,608,476
G
Eif2a
eukaryotic translation initiation factor 2A
increases phosphorylation
ISO
nivalenol results in increased phosphorylation of EIF2A protein
CTD
PMID:20682335
NCBI chr 2:144,911,247...144,944,705
Ensembl chr 2:144,911,153...144,945,201
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Eif3j
eukaryotic translation initiation factor 3, subunit J
increases expression
ISO
nivalenol results in increased expression of EIF3J protein
CTD
PMID:39638853
NCBI chr 3:129,438,715...129,460,953
Ensembl chr 3:129,438,722...129,462,246
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Eif4g2
eukaryotic translation initiation factor 4, gamma 2
increases expression
ISO
nivalenol results in increased expression of EIF4G2 protein
CTD
PMID:39638853
NCBI chr 1:174,616,102...174,628,252
Ensembl chr 1:174,616,103...174,628,252
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Eif6
eukaryotic translation initiation factor 6
increases expression
ISO
nivalenol results in increased expression of EIF6 protein
CTD
PMID:39638853
NCBI chr 3:164,785,162...164,791,410
Ensembl chr 3:164,785,163...164,791,525
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Eml4
EMAP like 4
decreases expression
ISO
nivalenol results in decreased expression of EML4 mRNA
CTD
PMID:35016910
NCBI chr 6:11,219,545...11,334,824
Ensembl chr 6:16,972,075...17,087,439
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Eno2
enolase 2
decreases expression
ISO
nivalenol results in decreased expression of ENO2 protein
CTD
PMID:39638853
NCBI chr 4:159,258,371...159,267,220
Ensembl chr 4:159,258,371...159,267,220
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Epb41l5
erythrocyte membrane protein band 4.1 like 5
increases expression
ISO
nivalenol results in increased expression of EPB41L5 protein
CTD
PMID:39638853
NCBI chr13:30,670,792...30,770,213
Ensembl chr13:33,223,589...33,321,133
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Epha2
Eph receptor A2
increases expression
ISO
nivalenol results in increased expression of EPHA2 protein
CTD
PMID:39638853
NCBI chr 5:158,888,629...158,917,100
Ensembl chr 5:158,888,629...158,917,234
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Ermp1
endoplasmic reticulum metallopeptidase 1
increases expression
ISO
nivalenol results in increased expression of ERMP1 mRNA
CTD
PMID:35016910
NCBI chr 1:236,801,459...236,835,656
Ensembl chr 1:236,801,466...236,839,197
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Ern1
endoplasmic reticulum to nucleus signaling 1
increases expression
ISO
nivalenol results in increased expression of ERN1 mRNA
CTD
PMID:35016910
NCBI chr10:91,826,663...91,920,976
Ensembl chr10:91,830,428...91,920,791
G
F11r
F11 receptor
decreases expression
ISO
nivalenol results in decreased expression of F11R protein
CTD
PMID:39638853
NCBI chr13:86,406,229...86,429,819
Ensembl chr13:86,406,218...86,429,816
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F2
coagulation factor II, thrombin
decreases expression
ISO
nivalenol results in decreased expression of F2 protein
CTD
PMID:39638853
NCBI chr 3:98,051,958...98,065,246
Ensembl chr 3:98,051,960...98,065,246
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Fads2
fatty acid desaturase 2
decreases expression
ISO
nivalenol results in decreased expression of FADS2 protein
CTD
PMID:39638853
NCBI chr 1:216,132,277...216,172,190
Ensembl chr 1:216,133,676...216,172,066
G
Fasn
fatty acid synthase
decreases expression
ISO
nivalenol results in decreased expression of FASN protein
CTD
PMID:39638853
NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,570,413...106,588,583
G
Fbxo2
F-box protein 2
decreases expression
ISO
nivalenol results in decreased expression of FBXO2 protein
CTD
PMID:39638853
NCBI chr 5:163,876,079...163,881,508
Ensembl chr 5:163,875,757...163,881,508
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Fcgrt
Fc gamma receptor and transporter
decreases expression
ISO
nivalenol results in decreased expression of FCGRT protein
CTD
PMID:39638853
NCBI chr 1:104,710,902...104,720,685
Ensembl chr 1:104,710,909...104,720,532
G
Fras1
Fraser extracellular matrix complex subunit 1
decreases expression
ISO
nivalenol results in decreased expression of FRAS1 protein
CTD
PMID:39638853
NCBI chr14:13,095,370...13,506,895
Ensembl chr14:13,095,370...13,504,664
G
Fry
FRY microtubule binding protein
decreases expression
ISO
nivalenol results in decreased expression of FRY mRNA
CTD
PMID:35016910
NCBI chr12:9,530,360...9,773,391
Ensembl chr12:9,530,360...9,897,603
G
Ftsj3
FtsJ RNA 2'-O-methyltransferase 3
increases expression
ISO
nivalenol results in increased expression of FTSJ3 protein
CTD
PMID:39638853
NCBI chr10:91,680,735...91,687,475
Ensembl chr10:91,680,753...91,687,179
G
Galk1
galactokinase 1
decreases expression
ISO
nivalenol results in decreased expression of GALK1 protein
CTD
PMID:39638853
NCBI chr10:101,742,067...101,746,244
Ensembl chr10:101,735,061...101,746,258
G
Galm
galactose mutarotase
decreases expression
ISO
nivalenol results in decreased expression of GALM protein
CTD
PMID:39638853
NCBI chr 6:20,589,775...20,641,516
Ensembl chr 6:20,589,776...20,644,417
G
Gamt
guanidinoacetate N-methyltransferase
decreases expression
ISO
nivalenol results in decreased expression of GAMT protein
CTD
PMID:39638853
NCBI chr 7:9,448,590...9,451,413
Ensembl chr 7:10,098,571...10,102,083
G
Gclc
glutamate-cysteine ligase, catalytic subunit
increases expression
ISO
nivalenol results in increased expression of GCLC protein
CTD
PMID:39638853
NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:87,510,463...87,548,893
G
Gdf15
growth differentiation factor 15
increases expression
ISO
nivalenol results in increased expression of GDF15 protein
CTD
PMID:39638853
NCBI chr16:18,838,436...18,842,022
Ensembl chr16:18,838,436...18,842,022
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Get4
guided entry of tail-anchored proteins factor 4
decreases expression
ISO
nivalenol results in decreased expression of GET4 mRNA
CTD
PMID:35016910
NCBI chr12:15,377,009...15,394,238
Ensembl chr12:20,490,861...20,555,240
G
Gfpt1
glutamine fructose-6-phosphate transaminase 1
decreases expression
ISO
nivalenol results in decreased expression of GFPT1 protein
CTD
PMID:39638853
NCBI chr 4:119,496,691...119,546,472
Ensembl chr 4:121,054,045...121,103,799
G
Gh1
growth hormone 1
decreases expression multiple interactions
EXP
nivalenol results in decreased expression of GH1 mRNA nivalenol results in decreased expression of and results in decreased secretion of GH1 protein
CTD
PMID:26141394
NCBI chr10:91,727,883...91,729,860
Ensembl chr10:91,727,884...91,729,859
G
Gnl3
G protein nucleolar 3
increases expression
ISO
nivalenol results in increased expression of GNL3 protein
CTD
PMID:39638853
NCBI chr16:6,213,844...6,220,029
Ensembl chr16:6,213,871...6,219,845
G
Golga4
golgin A4
decreases expression
ISO
nivalenol results in decreased expression of GOLGA4 mRNA
CTD
PMID:35016910
NCBI chr 8:127,085,830...127,163,227
Ensembl chr 8:127,085,848...127,163,603
G
Golph3
golgi phosphoprotein 3
increases expression
ISO
nivalenol results in increased expression of GOLPH3 mRNA
CTD
PMID:35016910
NCBI chr 2:61,348,030...61,376,051
Ensembl chr 2:63,074,256...63,113,577
G
Gopc
golgi associated PDZ and coiled-coil motif containing
increases expression
ISO
nivalenol results in increased expression of GOPC mRNA
CTD
PMID:35016910
NCBI chr20:31,727,617...31,776,904
Ensembl chr20:32,270,314...32,319,611
G
Gpd2
glycerol-3-phosphate dehydrogenase 2
increases expression
ISO
nivalenol results in increased expression of GPD2 mRNA
CTD
PMID:35016910
NCBI chr 3:41,800,552...41,937,729
Ensembl chr 3:62,210,814...62,346,593
G
Grwd1
glutamate-rich WD repeat containing 1
increases expression
ISO
nivalenol results in increased expression of GRWD1 protein
CTD
PMID:39638853
NCBI chr 1:105,437,708...105,443,410
Ensembl chr 1:105,437,709...105,443,825
G
Gtpbp4
GTP binding protein 4
increases expression
ISO
nivalenol results in increased expression of GTPBP4 protein
CTD
PMID:39638853
NCBI chr17:65,997,472...66,019,530
Ensembl chr17:66,276,566...66,289,637
G
Guf1
GTP binding elongation factor GUF1
increases expression
ISO
nivalenol results in increased expression of GUF1 protein
CTD
PMID:39638853
NCBI chr14:38,891,905...38,911,283
Ensembl chr14:38,891,905...38,911,283
G
Hdlbp
high density lipoprotein binding protein
decreases expression
ISO
nivalenol results in decreased expression of HDLBP protein
CTD
PMID:39638853
NCBI chr 9:101,395,491...101,465,446
Ensembl chr 9:101,397,305...101,465,379
G
Herpud1
homocysteine inducible ER protein with ubiquitin like domain 1
increases expression
ISO
nivalenol results in increased expression of HERPUD1 mRNA
CTD
PMID:35016910
NCBI chr19:10,604,360...10,624,168
Ensembl chr19:10,604,362...10,624,081
G
Hmox1
heme oxygenase 1
decreases expression
ISO
nivalenol results in decreased expression of HMOX1 protein
CTD
PMID:39638853
NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
G
Hnrnpf
heterogeneous nuclear ribonucleoprotein F
increases expression
ISO
nivalenol results in increased expression of HNRNPF protein
CTD
PMID:39638853
NCBI chr 4:152,755,668...152,776,867
Ensembl chr 4:152,722,617...152,815,769
G
Hook1
hook microtubule-tethering protein 1
increases expression
ISO
nivalenol results in increased expression of HOOK1 mRNA
CTD
PMID:35016910
NCBI chr 5:110,824,501...110,887,791
Ensembl chr 5:115,940,080...116,003,482
G
Hook2
hook microtubule-tethering protein 2
increases expression
ISO
nivalenol results in increased expression of HOOK2 mRNA
CTD
PMID:35016910
NCBI chr19:40,056,732...40,075,027
Ensembl chr19:40,056,732...40,081,270
G
Hspa5
heat shock protein family A (Hsp70) member 5
decreases expression
ISO
nivalenol results in decreased expression of HSPA5 mRNA
CTD
PMID:20682335
NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790
G
Hspb1
heat shock protein family B (small) member 1
decreases expression
ISO
nivalenol results in decreased expression of HSPB1 protein
CTD
PMID:39638853
NCBI chr12:26,430,640...26,432,301
Ensembl chr12:26,430,640...26,432,301
G
Ifnb1
interferon beta 1
multiple interactions
ISO
nivalenol inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IFNB1 mRNA]
CTD
PMID:19857559
NCBI chr 5:108,066,650...108,067,487
Ensembl chr 5:108,066,650...108,067,487
G
Ifng
interferon gamma
affects expression
ISO
nivalenol affects the expression of IFNG mRNA
CTD
PMID:17166736
NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216
G
Il13
interleukin 13
multiple interactions
ISO
[Toluene 2,4-Diisocyanate co-treated with nivalenol] results in increased secretion of IL13 protein
CTD
PMID:38616237
NCBI chr10:38,290,926...38,293,483
Ensembl chr10:38,290,926...38,293,483
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Il1b
interleukin 1 beta
increases expression
ISO
nivalenol results in increased expression of IL1B mRNA
CTD
PMID:24793808 PMID:38616237
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
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Il2
interleukin 2
affects expression affects secretion increases expression
ISO
nivalenol affects the expression of IL2 mRNA nivalenol affects the secretion of IL2 protein nivalenol results in increased expression of IL2 mRNA
CTD
PMID:8560498 PMID:17166736
NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672
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Il4
interleukin 4
affects secretion multiple interactions increases expression
ISO
nivalenol affects the secretion of IL4 protein [Toluene 2,4-Diisocyanate co-treated with nivalenol] results in increased secretion of IL4 protein nivalenol results in increased expression of IL4 mRNA
CTD
PMID:8560498 PMID:38616237
NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549
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Il5
interleukin 5
affects secretion multiple interactions
ISO
nivalenol affects the secretion of IL5 protein [Toluene 2,4-Diisocyanate co-treated with nivalenol] results in increased secretion of IL5 protein
CTD
PMID:8560498 PMID:38616237
NCBI chr10:38,375,132...38,378,003
Ensembl chr10:38,375,132...38,378,003
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Il6
interleukin 6
increases expression
ISO
nivalenol results in increased expression of IL6 mRNA
CTD
PMID:38616237
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
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Ilf3
interleukin enhancer binding factor 3
increases expression
ISO
nivalenol results in increased expression of ILF3 protein
CTD
PMID:39638853
NCBI chr 8:28,198,454...28,236,634
Ensembl chr 8:28,198,543...28,236,612
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Inf2
inverted formin 2
increases expression
ISO
nivalenol results in increased expression of INF2 protein
CTD
PMID:39638853
NCBI chr 6:131,649,162...131,675,944
Ensembl chr 6:137,470,286...137,497,039
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Itih2
inter-alpha-trypsin inhibitor heavy chain 2
decreases expression
ISO
nivalenol results in decreased expression of ITIH2 protein
CTD
PMID:39638853
NCBI chr17:73,285,281...73,321,555
Ensembl chr17:73,285,270...73,321,547
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Itm2b
integral membrane protein 2B
decreases expression
ISO
nivalenol results in decreased expression of ITM2B protein
CTD
PMID:39638853
NCBI chr15:54,955,549...54,978,455
Ensembl chr15:54,955,552...54,978,455
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Kdelr2
KDEL endoplasmic reticulum protein retention receptor 2
increases expression
ISO
nivalenol results in increased expression of KDELR2 mRNA
CTD
PMID:35016910
NCBI chr12:11,138,820...11,157,117
Ensembl chr12:16,252,424...16,270,719
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Krr1
KRR1, small subunit processome component homolog
increases expression
ISO
nivalenol results in increased expression of KRR1 protein
CTD
PMID:39638853
NCBI chr 7:49,361,794...49,374,222
Ensembl chr 7:49,361,901...49,374,216
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Krt18
keratin 18
increases expression
ISO
nivalenol results in increased expression of KRT18 protein
CTD
PMID:39638853
NCBI chr 7:135,036,168...135,039,844
Ensembl chr 7:135,035,982...135,039,848 Ensembl chr10:135,035,982...135,039,848
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Lama5
laminin subunit alpha 5
decreases expression
ISO
nivalenol results in decreased expression of LAMA5 protein
CTD
PMID:39638853
NCBI chr 3:187,647,904...187,695,974
Ensembl chr 3:187,647,904...187,696,173
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Lamp2
lysosomal-associated membrane protein 2
increases expression
ISO
nivalenol results in increased expression of LAMP2 mRNA
CTD
PMID:35016910
NCBI chr X:122,038,734...122,087,745
Ensembl chr X:121,922,187...122,087,675
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Laptm4a
lysosomal protein transmembrane 4 alpha
decreases expression
ISO
nivalenol results in decreased expression of LAPTM4A protein
CTD
PMID:39638853
NCBI chr 6:37,438,503...37,456,238
Ensembl chr 6:37,438,121...37,456,223
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Larp4
La ribonucleoprotein 4
increases expression
ISO
nivalenol results in increased expression of LARP4 protein
CTD
PMID:39638853
NCBI chr 7:132,983,276...133,031,514
Ensembl chr 7:132,980,385...133,029,633
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Lgals3bp
galectin 3 binding protein
decreases expression
ISO
nivalenol results in decreased expression of LGALS3BP protein
CTD
PMID:39638853
NCBI chr10:104,118,510...104,127,848
Ensembl chr10:104,118,510...104,127,848
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Lipa
lipase A, lysosomal acid type
decreases expression
ISO
nivalenol results in decreased expression of LIPA protein
CTD
PMID:39638853
NCBI chr 1:241,437,524...241,470,936
Ensembl chr 1:241,437,524...241,470,740
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Lrp1
LDL receptor related protein 1
decreases expression
ISO
nivalenol results in decreased expression of LRP1 protein
CTD
PMID:39638853
NCBI chr 7:65,265,639...65,346,196
Ensembl chr 7:65,265,639...65,346,196
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Lss
lanosterol synthase
decreases expression
ISO
nivalenol results in decreased expression of LSS protein
CTD
PMID:39638853
NCBI chr20:12,090,641...12,118,230
Ensembl chr20:12,073,543...12,118,253
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Macf1
microtubule-actin crosslinking factor 1
decreases expression
ISO
nivalenol results in decreased expression of MACF1 mRNA
CTD
PMID:35016910
NCBI chr 5:140,908,829...141,234,127
Ensembl chr 5:140,908,837...141,233,890
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Map1lc3b
microtubule-associated protein 1 light chain 3 beta
decreases expression
ISO
nivalenol results in decreased expression of MAP1LC3B mRNA
CTD
PMID:35016910
NCBI chr19:66,571,631...66,582,270
Ensembl chr19:66,574,407...66,584,358 Ensembl chr16:66,574,407...66,584,358
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Map2
microtubule-associated protein 2
increases expression
ISO
nivalenol results in increased expression of MAP2 mRNA
CTD
PMID:35016910
NCBI chr 9:75,173,038...75,431,606
Ensembl chr 9:75,288,262...75,428,459
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Map4
microtubule-associated protein 4
increases expression
ISO
nivalenol results in increased expression of MAP4 mRNA
CTD
PMID:35016910
NCBI chr 8:118,800,393...118,942,805
Ensembl chr 8:118,804,022...118,942,805
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Mapk1
mitogen activated protein kinase 1
increases phosphorylation
ISO
nivalenol results in increased phosphorylation of MAPK1 protein
CTD
PMID:38616237
NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
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Mapk3
mitogen activated protein kinase 3
increases phosphorylation
ISO
nivalenol results in increased phosphorylation of MAPK3 protein
CTD
PMID:38616237
NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
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Mapk8
mitogen-activated protein kinase 8
increases phosphorylation
ISO
nivalenol results in increased phosphorylation of MAPK8 protein
CTD
PMID:38616237
NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427
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Mapre1
microtubule-associated protein, RP/EB family, member 1
increases expression
ISO
nivalenol results in increased expression of MAPRE1 mRNA
CTD
PMID:35016910
NCBI chr 3:162,679,020...162,707,167
Ensembl chr 3:162,673,195...162,711,210
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Mapre2
microtubule-associated protein, RP/EB family, member 2
increases expression
ISO
nivalenol results in increased expression of MAPRE2 mRNA
CTD
PMID:35016910
NCBI chr18:15,303,502...15,444,306
Ensembl chr18:15,303,533...15,442,796
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Mark2
microtubule affinity regulating kinase 2
increases expression
ISO
nivalenol results in increased expression of MARK2 mRNA
CTD
PMID:35016910
NCBI chr 1:213,890,213...213,955,417
Ensembl chr 1:213,890,213...213,955,149
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Mast2
microtubule associated serine/threonine kinase 2
decreases expression
ISO
nivalenol results in decreased expression of MAST2 mRNA
CTD
PMID:35016910
NCBI chr 5:135,013,006...135,152,195
Ensembl chr 5:135,012,058...135,152,161
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Mgme1
mitochondrial genome maintenance exonuclease 1
increases expression
ISO
nivalenol results in increased expression of MGME1 protein
CTD
PMID:39638853
NCBI chr 3:152,094,514...152,103,314
Ensembl chr 3:152,094,658...152,103,313
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Mitd1
microtubule interacting and trafficking domain containing 1
increases expression
ISO
nivalenol results in increased expression of MITD1 mRNA
CTD
PMID:35016910
NCBI chr 9:47,609,743...47,621,033
Ensembl chr 9:47,609,744...47,621,033
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Mki67
marker of proliferation Ki-67
increases expression
ISO
nivalenol results in increased expression of MKI67 protein
CTD
PMID:39638853
NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:199,926,150...199,952,593
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Mrm1
mitochondrial rRNA methyltransferase 1
increases expression
ISO
nivalenol results in increased expression of MRM1 protein
CTD
PMID:39638853
NCBI chr10:70,187,842...70,194,785
Ensembl chr10:70,188,748...70,194,131
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Mrpl12
mitochondrial ribosomal protein L12
increases expression
ISO
nivalenol results in increased expression of MRPL12 protein
CTD
PMID:39638853
NCBI chr10:106,256,746...106,261,249
Ensembl chr10:106,256,547...106,263,088
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Msh6
mutS homolog 6
decreases expression
ISO
nivalenol results in decreased expression of MSH6 protein
CTD
PMID:39638853
NCBI chr 6:12,316,190...12,333,505
Ensembl chr 6:12,316,198...12,333,844
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Mta1
metastasis associated 1
increases expression
ISO
nivalenol results in increased expression of MTA1 protein
CTD
PMID:39638853
NCBI chr 6:137,999,845...138,038,696
Ensembl chr 6:137,999,915...138,038,696
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Mtrex
Mtr4 exosome RNA helicase
increases expression
ISO
nivalenol results in increased expression of MTREX protein
CTD
PMID:39638853
NCBI chr 2:46,233,528...46,293,827
Ensembl chr 2:46,194,647...46,293,827
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Muc5ac
mucin 5AC, oligomeric mucus/gel-forming
multiple interactions increases expression
ISO
nivalenol results in increased expression of and results in increased secretion of MUC5AC protein nivalenol results in increased expression of MUC5AC mRNA
CTD
PMID:24496642
NCBI chr 1:206,293,717...206,326,006
Ensembl chr 1:206,293,869...206,326,006
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Muc5b
mucin 5B, oligomeric mucus/gel-forming
increases expression multiple interactions
ISO
nivalenol results in increased expression of MUC5B mRNA nivalenol results in increased expression of and results in increased secretion of MUC5B protein
CTD
PMID:24496642
NCBI chr 1:206,346,400...206,378,367
Ensembl chr 1:206,346,400...206,378,367
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Myo1c
myosin 1C
increases expression
ISO
nivalenol results in increased expression of MYO1C protein
CTD
PMID:39638853
NCBI chr10:60,996,642...61,019,022
Ensembl chr10:60,996,638...61,019,022
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Ncl
nucleolin
increases expression
ISO
nivalenol results in increased expression of NCL protein
CTD
PMID:39638853
NCBI chr 9:94,447,559...94,456,083
Ensembl chr 9:94,446,682...94,456,083
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Nhp2
NHP2 ribonucleoprotein
increases expression
ISO
nivalenol results in increased expression of NHP2 protein
CTD
PMID:39638853
NCBI chr10:36,378,020...36,381,362
Ensembl chr10:36,377,997...36,381,354
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Nid1
nidogen 1
decreases expression
ISO
nivalenol results in decreased expression of NID1 protein
CTD
PMID:39638853
NCBI chr17:93,069,013...93,142,416
Ensembl chr17:93,069,278...93,142,386
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Nkrf
NFKB repressing factor
increases expression
ISO
nivalenol results in increased expression of NKRF protein
CTD
PMID:39638853
NCBI chr X:120,992,038...121,010,251
Ensembl chr X:120,992,038...121,010,251
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Nle1
notchless homolog 1
increases expression
ISO
nivalenol results in increased expression of NLE1 protein
CTD
PMID:39638853
NCBI chr10:68,331,609...68,342,562
Ensembl chr10:68,331,609...68,340,386
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Nop16
NOP16 nucleolar protein
increases expression
ISO
nivalenol results in increased expression of NOP16 protein
CTD
PMID:39638853
NCBI chr17:10,028,058...10,032,975
Ensembl chr17:10,028,034...10,033,038
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Nop58
NOP58 ribonucleoprotein
increases expression
ISO
nivalenol results in increased expression of NOP58 protein
CTD
PMID:39638853
NCBI chr 9:68,614,992...68,638,911
Ensembl chr 9:68,615,010...68,638,909
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Nos2
nitric oxide synthase 2
multiple interactions
ISO
nivalenol inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 mRNA]; nivalenol inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 protein]
CTD
PMID:19857559
NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
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Npm1
nucleophosmin 1
increases expression
ISO
nivalenol results in increased expression of NPM1 protein
CTD
PMID:39638853
NCBI chr10:18,245,739...18,255,913
Ensembl chr10:18,245,740...18,256,024 Ensembl chr X:18,245,740...18,256,024
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Nsa2
NSA2 ribosome biogenesis factor
increases expression
ISO
nivalenol results in increased expression of NSA2 protein
CTD
PMID:39638853
NCBI chr 2:30,177,753...30,184,004
Ensembl chr 2:30,177,702...30,184,031
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Nsun5
NOP2/Sun RNA methyltransferase 5
increases expression
ISO
nivalenol results in increased expression of NSUN5 protein
CTD
PMID:39638853
NCBI chr12:26,930,204...26,935,887
Ensembl chr12:26,930,863...26,936,130
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Nt5e
5' nucleotidase, ecto
decreases expression
ISO
nivalenol results in decreased expression of NT5E protein
CTD
PMID:39638853
NCBI chr 8:98,150,925...98,195,646
Ensembl chr 8:98,150,900...98,195,645
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Nufip2
nuclear FMR1 interacting protein 2
increases expression
ISO
nivalenol results in increased expression of NUFIP2 protein
CTD
PMID:39638853
NCBI chr10:63,072,964...63,105,823
Ensembl chr10:63,073,397...63,105,823
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Os9
OS9, endoplasmic reticulum lectin
decreases expression
ISO
nivalenol results in decreased expression of OS9 protein
CTD
PMID:39638853
NCBI chr 7:64,802,517...64,829,185
Ensembl chr 7:64,802,103...64,829,070
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Pabpc1
poly(A) binding protein, cytoplasmic 1
increases expression
ISO
nivalenol results in increased expression of PABPC1 protein
CTD
PMID:39638853
NCBI chr 7:69,662,513...69,674,806
Ensembl chr 7:69,663,068...69,675,050
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Parp1
poly (ADP-ribose) polymerase 1
increases cleavage
ISO
nivalenol results in increased cleavage of PARP1 protein
CTD
PMID:19410639
NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567
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Pcsk9
proprotein convertase subtilisin/kexin type 9
decreases expression
ISO
nivalenol results in decreased expression of PCSK9 protein
CTD
PMID:39638853
NCBI chr 5:126,440,102...126,462,507
Ensembl chr 5:126,440,102...126,462,507
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Pde12
phosphodiesterase 12
increases expression
ISO
nivalenol results in increased expression of PDE12 protein
CTD
PMID:39638853
NCBI chr16:1,926,807...1,932,383
Ensembl chr16:1,922,131...1,932,611
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Peg3
paternally expressed 3
decreases expression
ISO
nivalenol results in decreased expression of PEG3 protein
CTD
PMID:39638853
NCBI chr 1:67,097,874...67,124,692
Ensembl chr 1:76,130,948...76,157,743
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Pepd
peptidase D
decreases expression
ISO
nivalenol results in decreased expression of PEPD protein
CTD
PMID:39638853
NCBI chr 1:96,673,624...96,818,197
Ensembl chr 1:96,673,607...96,818,190
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Pes1
pescadillo ribosomal biogenesis factor 1
increases expression
ISO
nivalenol results in increased expression of PES1 protein
CTD
PMID:39638853
NCBI chr14:83,074,346...83,090,726
Ensembl chr14:83,074,319...83,091,718
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Phgdh
phosphoglycerate dehydrogenase
decreases expression
ISO
nivalenol results in decreased expression of PHGDH protein
CTD
PMID:39638853
NCBI chr 2:188,595,700...188,624,789
Ensembl chr 2:188,595,700...188,624,789
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Pkp3
plakophilin 3
increases expression
ISO
nivalenol results in increased expression of PKP3 protein
CTD
PMID:39638853
NCBI chr 1:205,617,511...205,628,441
Ensembl chr 1:205,617,511...205,628,440
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Plin2
perilipin 2
increases expression
ISO
nivalenol results in increased expression of PLIN2 protein
CTD
PMID:39638853
NCBI chr 5:106,202,634...106,258,748
Ensembl chr 5:106,202,634...106,258,878
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Plod1
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
decreases expression
ISO
nivalenol results in decreased expression of PLOD1 protein
CTD
PMID:39638853
NCBI chr 5:163,623,847...163,650,737
Ensembl chr 5:163,623,848...163,651,110
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Plod2
procollagen lysine, 2-oxoglutarate 5-dioxygenase 2
decreases expression
ISO
nivalenol results in decreased expression of PLOD2 protein
CTD
PMID:39638853
NCBI chr 8:101,964,318...102,047,022
Ensembl chr 8:101,964,318...102,047,022
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Pparg
peroxisome proliferator-activated receptor gamma
decreases activity
ISO
nivalenol results in decreased activity of PPARG protein
CTD
PMID:27481073
NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104
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Pphln1
periphilin 1
increases expression
ISO
nivalenol results in increased expression of PPHLN1 protein
CTD
PMID:39638853
NCBI chr 7:124,538,594...124,629,985
Ensembl chr 7:126,417,555...126,509,430
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Prdx2
peroxiredoxin 2
decreases expression
ISO
nivalenol results in decreased expression of PRDX2 protein
CTD
PMID:39638853
NCBI chr19:40,085,788...40,091,083
Ensembl chr19:40,084,430...40,091,006
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Prkar2a
protein kinase cAMP-dependent type II regulatory subunit alpha
increases expression
ISO
nivalenol results in increased expression of PRKAR2A protein
CTD
PMID:39638853
NCBI chr 8:118,271,608...118,337,332
Ensembl chr 8:118,274,167...118,337,330
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Prodh2
proline dehydrogenase 2
increases expression
ISO
nivalenol results in increased expression of PRODH2 protein
CTD
PMID:39638853
NCBI chr 1:85,753,558...85,767,165
Ensembl chr 1:94,881,061...94,894,609
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Psat1
phosphoserine aminotransferase 1
decreases expression
ISO
nivalenol results in decreased expression of PSAT1 protein
CTD
PMID:39638853
NCBI chr 1:222,623,553...222,646,187
Ensembl chr 1:222,623,556...222,655,693
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Pspc1
paraspeckle component 1
increases expression
ISO
nivalenol results in increased expression of PSPC1 protein
CTD
PMID:39638853
NCBI chr15:34,941,445...35,027,460
Ensembl chr15:34,967,477...35,026,828
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Rab11a
RAB11a, member RAS oncogene family
increases expression
ISO
nivalenol results in increased expression of RAB11A protein
CTD
PMID:35016910
NCBI chr 8:74,118,922...74,141,760
Ensembl chr 8:74,118,922...74,141,837
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Rad50
RAD50 double strand break repair protein
increases expression
ISO
nivalenol results in increased expression of RAD50 protein
CTD
PMID:39638853
NCBI chr10:38,310,147...38,362,100
Ensembl chr10:38,310,147...38,362,100
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Rae1
ribonucleic acid export 1
increases expression
ISO
nivalenol results in increased expression of RAE1 protein
CTD
PMID:39638853
NCBI chr 3:182,197,432...182,212,381
Ensembl chr 3:182,197,459...182,213,135
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Rap1a
RAP1A, member of RAS oncogene family
increases expression
ISO
nivalenol results in increased expression of RAP1A protein
CTD
PMID:39638853
NCBI chr 2:193,208,631...193,286,513
Ensembl chr 2:195,896,971...195,974,808
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Rbm17
RNA binding motif protein 17
increases expression
ISO
nivalenol results in increased expression of RBM17 protein
CTD
PMID:39638853
NCBI chr17:71,846,941...71,863,834
Ensembl chr17:71,846,916...71,864,431
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Rbm34
RNA binding motif protein 34
increases expression
ISO
nivalenol results in increased expression of RBM34 protein
CTD
PMID:39638853
NCBI chr19:71,832,189...71,854,038
Ensembl chr19:71,833,763...71,853,946
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Riox1
ribosomal oxygenase 1
increases expression
ISO
nivalenol results in increased expression of RIOX1 protein
CTD
PMID:39638853
NCBI chr 6:109,310,748...109,313,365
Ensembl chr 6:109,286,568...109,314,355
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Riox2
ribosomal oxygenase 2
increases expression
ISO
nivalenol results in increased expression of RIOX2 protein
CTD
PMID:39638853
NCBI chr11:54,327,311...54,353,989
Ensembl chr11:54,330,605...54,353,752
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Rnmt
RNA (guanine-7-) methyltransferase
increases expression
ISO
nivalenol results in increased expression of RNMT protein
CTD
PMID:39638853
NCBI chr18:64,156,067...64,179,601
Ensembl chr18:64,156,154...64,179,500
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Rrp9
ribosomal RNA processing 9, U3 small nucleolar RNA binding protein
increases expression
ISO
nivalenol results in increased expression of RRP9 protein
CTD
PMID:39638853
NCBI chr 8:115,995,119...116,004,832
Ensembl chr 8:115,996,169...116,004,824
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Rrs1
ribosome biogenesis regulator 1 homolog
increases expression
ISO
nivalenol results in increased expression of RRS1 protein
CTD
PMID:39638853
NCBI chr 5:14,516,303...14,517,936
Ensembl chr 5:14,515,254...14,517,943
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Rsl1d1
ribosomal L1 domain containing 1
increases expression
ISO
nivalenol results in increased expression of RSL1D1 protein
CTD
PMID:39638853
NCBI chr10:4,931,839...4,943,726
Ensembl chr10:4,904,792...4,946,566
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Rsl24d1
ribosomal L24 domain containing 1
increases expression
ISO
nivalenol results in increased expression of RSL24D1 protein
CTD
PMID:39638853
NCBI chr 8:82,733,627...82,742,632
Ensembl chr 8:82,733,649...82,744,497
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RT1-CE16
RT1 class I, locus CE16
decreases expression
ISO
nivalenol results in decreased expression of HLA-A protein
CTD
PMID:39638853
NCBI chr20:3,261,656...3,265,548
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Sdcbp
syndecan binding protein
decreases expression
ISO
nivalenol results in decreased expression of SDCBP protein
CTD
PMID:39638853
NCBI chr 5:24,245,279...24,314,712
Ensembl chr 5:24,245,033...24,326,197
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Sec61g
Sec61 translocon subunit gamma
decreases expression
ISO
nivalenol results in decreased expression of SEC61G protein
CTD
PMID:39638853
NCBI chr14:90,899,766...90,906,143
Ensembl chr 9:48,798,504...48,798,710 Ensembl chr14:48,798,504...48,798,710
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Serpina1
serpin family A member 1
decreases expression
ISO
nivalenol results in decreased expression of SERPINA1 protein
CTD
PMID:39638853
NCBI chr 6:128,631,101...128,653,125
Ensembl chr 6:128,619,382...128,660,703
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Serpinf1
serpin family F member 1
decreases expression
ISO
nivalenol results in decreased expression of SERPINF1 protein
CTD
PMID:39638853
NCBI chr10:60,748,504...60,760,898
Ensembl chr10:60,748,506...60,760,898
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Slc11a2
solute carrier family 11 member 2
decreases expression
ISO
nivalenol results in decreased expression of SLC11A2 protein
CTD
PMID:39638853
NCBI chr 7:133,381,878...133,429,921
Ensembl chr 7:133,381,878...133,418,941
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Sltm
SAFB-like, transcription modulator
increases expression
ISO
nivalenol results in increased expression of SLTM protein
CTD
PMID:39638853
NCBI chr 8:80,096,555...80,142,668
Ensembl chr 8:80,097,652...80,142,671
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Smchd1
structural maintenance of chromosomes flexible hinge domain containing 1
increases expression
ISO
nivalenol results in increased expression of SMCHD1 protein
CTD
PMID:39638853
NCBI chr 9:118,690,050...118,837,281
Ensembl chr 9:118,690,057...118,833,452
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Sptlc2
serine palmitoyltransferase, long chain base subunit 2
decreases expression
ISO
nivalenol results in decreased expression of SPTLC2 protein
CTD
PMID:39638853
NCBI chr 6:112,679,623...112,762,470
Ensembl chr 6:112,679,623...112,762,640
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Sqstm1
sequestosome 1
increases expression
ISO
nivalenol results in increased expression of SQSTM1 protein
CTD
PMID:39638853
NCBI chr10:35,026,598...35,037,750
Ensembl chr10:35,026,598...35,037,750
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Srsf7
serine and arginine rich splicing factor 7
increases expression
ISO
nivalenol results in increased expression of SRSF7 protein
CTD
PMID:39638853
NCBI chr 6:20,564,035...20,571,205
Ensembl chr 6:20,564,044...20,571,212
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Ssr1
signal sequence receptor subunit 1
decreases expression
ISO
nivalenol results in decreased expression of SSR1 protein
CTD
PMID:39638853
NCBI chr17:27,039,203...27,067,352
Ensembl chr17:27,039,269...27,067,348
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Stau1
staufen double-stranded RNA binding protein 1
increases expression
ISO
nivalenol results in increased expression of STAU1 protein
CTD
PMID:39638853
NCBI chr 3:176,099,053...176,144,947
Ensembl chr 3:176,099,053...176,144,947
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Sult1a1
sulfotransferase family 1A member 1
decreases expression
ISO
nivalenol results in decreased expression of SULT1A1 protein
CTD
PMID:39638853
NCBI chr 1:190,702,592...190,706,112
Ensembl chr 1:190,702,592...190,706,131
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Sun2
Sad1 and UNC84 domain containing 2
decreases expression
ISO
nivalenol results in decreased expression of SUN2 protein
CTD
PMID:39638853
NCBI chr 7:113,155,766...113,172,950
Ensembl chr 7:113,155,766...113,172,940
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Supt6h
SPT6 homolog, histone chaperone and transcription elongation factor
increases expression
ISO
nivalenol results in increased expression of SUPT6H protein
CTD
PMID:39638853
NCBI chr10:63,601,990...63,638,851
Ensembl chr10:63,601,993...63,638,851
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Surf6
surfeit 6
increases expression
ISO
nivalenol results in increased expression of SURF6 protein
CTD
PMID:39638853
NCBI chr 3:30,619,525...30,630,388
Ensembl chr 3:30,619,530...30,630,247
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Tex264
testis expressed 264
increases expression
ISO
nivalenol results in increased expression of TEX264 protein
CTD
PMID:39638853
NCBI chr 8:116,174,517...116,201,578
Ensembl chr 8:116,174,518...116,201,667
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Tf
transferrin
decreases expression
ISO
nivalenol results in decreased expression of TF protein
CTD
PMID:39638853
NCBI chr 8:112,668,667...112,695,376
Ensembl chr 8:112,647,642...112,695,400
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Tfrc
transferrin receptor
decreases expression
ISO
nivalenol results in decreased expression of TFRC protein
CTD
PMID:39638853
NCBI chr11:81,668,478...81,690,318
Ensembl chr11:81,668,478...81,690,318
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Tgfbr3
transforming growth factor beta receptor 3
decreases expression
ISO
nivalenol results in decreased expression of TGFBR3 protein
CTD
PMID:39638853
NCBI chr14:2,634,294...2,810,269
Ensembl chr14:2,634,188...2,810,271
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Tkfc
triokinase and FMN cyclase
decreases expression
ISO
nivalenol results in decreased expression of TKFC protein
CTD
PMID:39638853
NCBI chr 1:216,664,446...216,677,815
Ensembl chr 1:216,661,477...216,677,928
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Tm9sf2
transmembrane 9 superfamily member 2
decreases expression
ISO
nivalenol results in decreased expression of TM9SF2 protein
CTD
PMID:39638853
NCBI chr15:105,606,082...105,660,715
Ensembl chr15:105,606,118...105,660,714
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Tm9sf4
transmembrane 9 superfamily member 4
decreases expression
ISO
nivalenol results in decreased expression of TM9SF4 protein
CTD
PMID:39638853
NCBI chr 3:162,086,758...162,135,620
Ensembl chr 3:162,087,347...162,151,721
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Tmem70
transmembrane protein 70
decreases expression
ISO
nivalenol results in decreased expression of TMEM70 protein
CTD
PMID:39638853
NCBI chr 5:7,420,396...7,438,023
Ensembl chr 5:7,420,396...7,438,023
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Tmt1b
thiol methyltransferase 1B
decreases expression
ISO
nivalenol results in decreased expression of TMT1B protein
CTD
PMID:39638853
NCBI chr 7:1,973,334...1,975,980
Ensembl chr 7:1,973,337...1,975,980
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Tnf
tumor necrosis factor
increases expression multiple interactions increases secretion
ISO
nivalenol results in increased expression of TNF mRNA 4-(9-(tetrahydrofuran-3-yl))-8-(2,4,6-trifluorophenylamino)-9H-purin-2-ylaminocyclohexan-1-ol inhibits the reaction [nivalenol results in increased secretion of TNF protein]; doramapimod inhibits the reaction [nivalenol results in increased secretion of TNF protein]; LY3214996 inhibits the reaction [nivalenol results in increased secretion of TNF protein]; pyrazolanthrone inhibits the reaction [nivalenol results in increased secretion of TNF protein]; SB 203580 inhibits the reaction [nivalenol results in increased secretion of TNF protein]; SCH772984 inhibits the reaction [nivalenol results in increased secretion of TNF protein]
CTD
PMID:38616237
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
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Toe1
target of EGR1, exonuclease
increases expression
ISO
nivalenol results in increased expression of TOE1 protein
CTD
PMID:39638853
NCBI chr 5:135,507,116...135,510,682
Ensembl chr 5:135,507,116...135,510,682
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Top1
DNA topoisomerase I
increases expression
ISO
nivalenol results in increased expression of TOP1 protein
CTD
PMID:39638853
NCBI chr 3:169,713,195...169,796,330
Ensembl chr 3:169,713,130...169,796,327
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Tpx2
TPX2, microtubule nucleation factor
increases expression
ISO
nivalenol results in increased expression of TPX2 mRNA nivalenol results in increased expression of TPX2 protein
CTD
PMID:35016910 PMID:39638853
NCBI chr 3:161,778,709...161,820,941
Ensembl chr 3:161,778,742...161,820,724
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Trim24
tripartite motif-containing 24
increases expression
ISO
nivalenol results in increased expression of TRIM24 protein
CTD
PMID:39638853
NCBI chr 4:67,534,240...67,659,014
Ensembl chr 4:67,534,335...67,684,226
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Trim28
tripartite motif-containing 28
increases expression
ISO
nivalenol results in increased expression of TRIM28 protein
CTD
PMID:39638853
NCBI chr 1:82,724,842...82,731,566
Ensembl chr 1:82,724,838...82,731,572
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Trip12
thyroid hormone receptor interactor 12
increases expression
ISO
nivalenol results in increased expression of TRIP12 protein
CTD
PMID:39638853
NCBI chr 9:93,364,791...93,491,015
Ensembl chr 9:93,364,791...93,490,159
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Trmt1l
tRNA methyltransferase 1-like
increases expression
ISO
nivalenol results in increased expression of TRMT1L protein
CTD
PMID:39638853
NCBI chr13:66,060,186...66,093,247
Ensembl chr13:66,060,162...66,093,643
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Tuba1b
tubulin, alpha 1B
decreases acetylation
ISO
nivalenol results in decreased acetylation of TUBA1B protein
CTD
PMID:35016910
NCBI chr 7:131,969,606...131,972,587
Ensembl chr 7:131,968,770...131,996,035
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Utp15
UTP15, small subunit processome component
increases expression
ISO
nivalenol results in increased expression of UTP15 protein
CTD
PMID:39638853
NCBI chr 2:31,329,222...31,347,022
Ensembl chr 2:31,329,223...31,347,046
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Utp18
UTP18 small subunit processome component
increases expression
ISO
nivalenol results in increased expression of UTP18 protein
CTD
PMID:39638853
NCBI chr10:79,308,785...79,336,241
Ensembl chr10:79,308,787...79,336,197
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Utp20
UTP20 small subunit processome component
increases expression
ISO
nivalenol results in increased expression of UTP20 protein
CTD
PMID:39638853
NCBI chr 7:25,022,029...25,103,024
Ensembl chr 7:25,022,036...25,103,041
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Vasn
vasorin
decreases expression
ISO
nivalenol results in decreased expression of VASN protein
CTD
PMID:39638853
NCBI chr10:11,424,174...11,434,681
Ensembl chr10:11,417,327...11,450,704
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Wdr46
WD repeat domain 46
increases expression
ISO
nivalenol results in increased expression of WDR46 protein
CTD
PMID:39638853
NCBI chr20:4,939,721...4,947,619
Ensembl chr20:4,939,732...4,947,741
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Wdr74
WD repeat domain 74
increases expression
ISO
nivalenol results in increased expression of WDR74 protein
CTD
PMID:39638853
NCBI chr 1:215,060,901...215,065,687
Ensembl chr 1:215,060,961...215,066,336
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Wdr75
WD repeat domain 75
increases expression
ISO
nivalenol results in increased expression of WDR75 protein
CTD
PMID:39638853
NCBI chr 9:55,395,232...55,425,412
Ensembl chr 9:55,395,222...55,425,412
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Whamm
WASP homolog associated with actin, golgi membranes and microtubules
increases expression
ISO
nivalenol results in increased expression of WHAMM mRNA
CTD
PMID:35016910
NCBI chr 1:144,935,588...144,963,989
Ensembl chr 1:144,935,618...144,964,385
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Ybx1
Y box binding protein 1
increases expression
ISO
nivalenol results in increased expression of YBX1 protein
CTD
PMID:39638853
NCBI chr 5:138,167,444...138,188,155
Ensembl chr 5:138,167,444...138,184,188
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Ybx3
Y box binding protein 3
increases expression
ISO
nivalenol results in increased expression of YBX3 protein
CTD
PMID:39638853
NCBI chr 4:166,861,180...166,884,532
Ensembl chr 4:166,861,181...166,884,691
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Zc3h14
zinc finger CCCH type containing 14
increases expression
ISO
nivalenol results in increased expression of ZC3H14 protein
CTD
PMID:39638853
NCBI chr 6:123,736,120...123,773,775
Ensembl chr 6:123,736,148...123,774,266
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Zfp512b
zinc finger protein 512B
increases expression
ISO
nivalenol results in increased expression of ZNF512B protein
CTD
PMID:39638853
NCBI chr 3:189,065,036...189,075,587
Ensembl chr 3:189,065,037...189,075,761
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Zfp687
zinc finger protein 687
increases expression
ISO
nivalenol results in increased expression of ZNF687 protein
CTD
PMID:39638853
NCBI chr 2:182,572,893...182,581,641
Ensembl chr 2:185,261,903...185,270,641
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Zfr
zinc finger RNA binding protein
increases expression
ISO
nivalenol results in increased expression of ZFR protein
CTD
PMID:39638853
NCBI chr 2:62,864,333...62,927,377
Ensembl chr 2:62,864,338...62,929,133
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Bax
BCL2 associated X, apoptosis regulator
increases expression
ISO
roridin A results in increased expression of BAX mRNA
CTD
PMID:17483119
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
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Cxcl2
C-X-C motif chemokine ligand 2
multiple interactions increases expression
ISO
lipopolysaccharide, Escherichia coli O111 B4 promotes the reaction [roridin A results in increased expression of CXCL2 mRNA]; roridin A promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of CXCL2 mRNA]
CTD
PMID:17483119
NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,465,242...17,467,255
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Dffb
DNA fragmentation factor subunit beta
increases expression
ISO
roridin A results in increased expression of DFFB mRNA
CTD
PMID:17483119
NCBI chr 5:169,804,873...169,817,157
Ensembl chr 5:169,804,889...169,817,225
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Eif2ak2
eukaryotic translation initiation factor 2-alpha kinase 2
multiple interactions increases expression
ISO
lipopolysaccharide, Escherichia coli O111 B4 promotes the reaction [roridin A results in increased expression of EIF2AK2 mRNA]; roridin A promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of EIF2AK2 mRNA]
CTD
PMID:17483119
NCBI chr 6:21,941,147...21,977,115
Ensembl chr 6:21,952,631...21,977,116
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Fas
Fas cell surface death receptor
multiple interactions increases expression
ISO
roridin A promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of FAS mRNA] roridin A results in increased expression of FAS mRNA
CTD
PMID:17483119
NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:241,205,935...241,246,104
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Faslg
Fas ligand
multiple interactions
ISO
roridin A promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of FASL mRNA]
CTD
PMID:17483119
NCBI chr13:76,680,885...76,706,042
Ensembl chr13:76,688,243...76,695,503
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Hspa5
heat shock protein family A (Hsp70) member 5
multiple interactions
ISO
roridin A results in increased degradation of and results in decreased expression of HSPA5 protein
CTD
PMID:19336499
NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790
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Il1a
interleukin 1 alpha
increases expression multiple interactions
ISO
roridin A results in increased expression of IL1A mRNA [lipopolysaccharide, Escherichia coli O111 B4 co-treated with roridin A] affects the expression of IL1A mRNA
CTD
PMID:17483119
NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013
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Il1b
interleukin 1 beta
increases expression multiple interactions
ISO
roridin A results in increased expression of IL1B mRNA [lipopolysaccharide, Escherichia coli O111 B4 co-treated with roridin A] affects the expression of IL1B mRNA
CTD
PMID:17483119
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
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Il6
interleukin 6
multiple interactions increases expression
ISO
lipopolysaccharide, Escherichia coli O111 B4 promotes the reaction [roridin A results in increased expression of IL6 mRNA]; roridin A promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 mRNA]
CTD
PMID:17483119
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
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Tnf
tumor necrosis factor
multiple interactions increases expression
ISO
[lipopolysaccharide, Escherichia coli O111 B4 co-treated with roridin A] affects the expression of TNF mRNA roridin A results in increased expression of TNF mRNA
CTD
PMID:17483119
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
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Tp53
tumor protein p53
increases expression
ISO
roridin A results in increased expression of TRP53 mRNA
CTD
PMID:17483119
NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
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Casp3
caspase 3
multiple interactions increases cleavage
EXP
pyrazolanthrone inhibits the reaction [satratoxin H results in increased cleavage of CASP3 protein]; SB 203580 inhibits the reaction [satratoxin H results in increased cleavage of CASP3 protein]
CTD
PMID:22863859
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
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H2ax
H2A.X variant histone
increases phosphorylation
EXP
satratoxin H results in increased phosphorylation of H2AX protein
CTD
PMID:22863859
NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079
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Parp1
poly (ADP-ribose) polymerase 1
increases cleavage
EXP
satratoxin H results in increased cleavage of PARP1 protein
CTD
PMID:22863859
NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567
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A2m
alpha-2-macroglobulin
multiple interactions decreases expression
ISO
Selenium inhibits the reaction [T-2 Toxin results in decreased expression of A2M mRNA]; Selenium promotes the reaction [T-2 Toxin results in decreased expression of A2M protein] T-2 Toxin results in decreased expression of A2M mRNA; T-2 Toxin results in decreased expression of A2M protein
CTD
PMID:21144892
NCBI chr 4:156,570,163...156,619,870
Ensembl chr 4:156,569,860...156,619,868
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Aars1
alanyl-tRNA synthetase 1
decreases expression
EXP ISO
T-2 Toxin results in decreased expression of AARS1 mRNA
CTD
PMID:26141394 PMID:34581912
NCBI chr19:55,906,694...55,930,499
Ensembl chr19:55,906,702...55,930,497
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Abcb1a
ATP binding cassette subfamily B member 1A
decreases expression
EXP
T-2 Toxin results in decreased expression of ABCB1A mRNA
CTD
PMID:26141394
NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135
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Abraxas2
abraxas 2, BRISC complex subunit
increases expression
ISO
T-2 Toxin results in increased expression of ABRAXAS2 mRNA
CTD
PMID:31863870
NCBI chr 1:197,077,177...197,102,753
Ensembl chr 1:197,077,158...197,102,757
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Acan
aggrecan
decreases expression
ISO
T-2 Toxin results in decreased expression of ACAN mRNA; T-2 Toxin results in decreased expression of ACAN protein
CTD
PMID:16624732 PMID:18196609 PMID:22800716 PMID:31863870
NCBI chr 1:142,390,951...142,453,779
Ensembl chr 1:142,390,951...142,453,779
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Acat2
acetyl-CoA acetyltransferase 2
affects expression
EXP
T-2 Toxin affects the expression of ACAT2 protein
CTD
PMID:26141394
NCBI chr 1:50,100,840...50,118,886
Ensembl chr 1:50,100,817...50,135,095
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Acly
ATP citrate lyase
decreases expression
EXP
T-2 Toxin results in decreased expression of ACLY mRNA
CTD
PMID:26141394
NCBI chr10:85,912,402...85,964,605
Ensembl chr10:85,912,402...85,963,631
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Aco2
aconitase 2
affects expression
EXP
T-2 Toxin affects the expression of ACO2 protein
CTD
PMID:26141394
NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:115,265,791...115,308,892
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Actb
actin, beta
affects expression
EXP
T-2 Toxin affects the expression of ACTB protein
CTD
PMID:26141394
NCBI chr12:16,776,664...16,779,634
Ensembl chr12:16,776,661...16,780,242
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Actr1a
actin related protein 1A
increases expression
ISO
T-2 Toxin results in increased expression of ACTR1A mRNA; T-2 Toxin results in increased expression of ACTR1A protein
CTD
PMID:34581912
NCBI chr 1:255,179,241...255,199,009
Ensembl chr 1:255,179,242...255,199,459
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Adam9
ADAM metallopeptidase domain 9
decreases expression
ISO
T-2 Toxin results in decreased expression of ADAM9 mRNA
CTD
PMID:34581912
NCBI chr16:73,725,186...73,804,284
Ensembl chr16:73,725,114...73,804,646
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Adamts4
ADAM metallopeptidase with thrombospondin type 1 motif, 4
increases expression
ISO
T-2 Toxin results in increased expression of ADAMTS4 mRNA
CTD
PMID:22800716
NCBI chr13:86,203,011...86,212,500
Ensembl chr13:86,202,642...86,212,514
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Adamts5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
increases expression
ISO
T-2 Toxin results in increased expression of ADAMTS5 mRNA
CTD
PMID:18196609 PMID:22800716
NCBI chr11:38,486,945...38,533,516
Ensembl chr11:38,486,955...38,533,516
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Adk
adenosine kinase
decreases expression
ISO
T-2 Toxin results in decreased expression of ADK protein
CTD
PMID:34581912
NCBI chr15:2,912,543...3,295,745
Ensembl chr15:2,912,544...3,295,745
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Adprh
ADP-ribosylarginine hydrolase
affects expression
EXP
T-2 Toxin affects the expression of ADPRH protein
CTD
PMID:26141394
NCBI chr11:75,805,347...75,811,686
Ensembl chr11:75,805,310...75,812,452
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Afg1l
AFG1 like ATPase
multiple interactions
EXP
T-2 Toxin promotes the reaction [GABPA protein binds to AFG1L]
CTD
PMID:36863559
NCBI chr20:47,380,582...47,550,307
Ensembl chr20:47,380,583...47,550,126
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Afg2a
AFG2 AAA ATPase homolog A
increases expression
EXP
T-2 Toxin results in increased expression of AFG2A mRNA
CTD
PMID:26141394
NCBI chr 2:120,306,417...120,497,707
Ensembl chr 2:122,234,738...122,425,808
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Ahcy
adenosylhomocysteinase
increases expression
ISO
T-2 Toxin results in increased expression of AHCY protein
CTD
PMID:34581912
NCBI chr 3:164,029,338...164,044,562
Ensembl chr 3:164,029,338...164,044,587
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Ahr
aryl hydrocarbon receptor
decreases expression
ISO
T-2 Toxin results in decreased expression of AHR protein
CTD
PMID:31470059
NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901
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Aimp2
aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
increases expression
ISO
T-2 Toxin results in increased expression of AIMP2 mRNA
CTD
PMID:34581912
NCBI chr12:15,814,854...15,824,432
Ensembl chr12:15,814,878...15,824,431
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Ak2
adenylate kinase 2
increases expression
ISO
T-2 Toxin results in increased expression of AK2 mRNA
CTD
PMID:31863870
NCBI chr 5:146,609,469...146,649,008
Ensembl chr 5:146,630,445...146,650,610
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Akap3
A-kinase anchoring protein 3
increases expression
ISO
T-2 Toxin results in increased expression of AKAP3 mRNA
CTD
PMID:34581912
NCBI chr 4:159,688,049...159,714,067
Ensembl chr 4:161,374,407...161,400,230
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Akap4
A-kinase anchoring protein 4
increases expression
ISO
T-2 Toxin results in increased expression of AKAP4 mRNA
CTD
PMID:34581912
NCBI chr X:18,107,256...18,117,549
Ensembl chr X:18,107,275...18,117,549
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Akirin2
akirin 2
increases expression
EXP ISO
T-2 Toxin results in increased expression of AKIRIN2 mRNA
CTD
PMID:26141394 PMID:34581912
NCBI chr 5:53,897,792...53,918,873
Ensembl chr 5:53,904,285...53,918,934
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Akna
AT-hook transcription factor
decreases expression affects localization multiple interactions
EXP
T-2 Toxin results in decreased expression of AKNA mRNA T-2 Toxin affects the localization of AKNA protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [T-2 Toxin results in decreased expression of AKNA mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [T-2 Toxin results in decreased expression of AKNA mRNA]; AKNA protein affects the reaction [T-2 Toxin results in decreased expression of GH1 mRNA]; AKNA protein affects the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; AKNA protein affects the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [T-2 Toxin results in decreased expression of AKNA mRNA]; SB 203580 inhibits the reaction [T-2 Toxin results in decreased expression of AKNA mRNA]; T-2 Toxin promotes the reaction [CREB1 protein binds to AKNA promoter]; T-2 Toxin promotes the reaction [RELA protein binds to AKNA promoter]
CTD
PMID:26141394 PMID:29079362
NCBI chr 5:81,792,928...81,839,936
Ensembl chr 5:81,792,929...81,831,528
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Akt1
AKT serine/threonine kinase 1
decreases expression multiple interactions increases phosphorylation
EXP ISO
T-2 Toxin results in decreased expression of AKT1 mRNA BTG2 protein affects the reaction [T-2 Toxin results in increased phosphorylation of AKT1 protein]
CTD
PMID:26141394 PMID:39147216
NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610
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Akt1s1
AKT1 substrate 1
increases expression
EXP
T-2 Toxin results in increased expression of AKT1S1 mRNA
CTD
PMID:26141394
NCBI chr 1:104,469,823...104,476,168
Ensembl chr 1:104,469,803...104,476,167
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Alas1
5'-aminolevulinate synthase 1
increases expression
ISO
T-2 Toxin results in increased expression of ALAS1 mRNA
CTD
PMID:34581912
NCBI chr 8:115,755,238...115,768,642
Ensembl chr 8:115,755,238...115,768,642
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Alas2
5'-aminolevulinate synthase 2
increases expression
ISO
T-2 Toxin results in increased expression of ALAS2 mRNA
CTD
PMID:34581912
NCBI chr X:22,890,650...22,914,046
Ensembl chr X:22,890,689...22,914,043
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Aldh1a1
aldehyde dehydrogenase 1 family, member A1
affects expression increases expression
EXP
T-2 Toxin affects the expression of ALDH1A1 protein T-2 Toxin results in increased expression of ALDH1A1 mRNA
CTD
PMID:26141394
NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:227,427,070...227,579,500
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Aldoc
aldolase, fructose-bisphosphate C
decreases expression
EXP
T-2 Toxin results in decreased expression of ALDOC mRNA
CTD
PMID:26141394
NCBI chr10:63,715,544...63,719,133
Ensembl chr10:63,715,489...63,719,133
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Alpl
alkaline phosphatase, biomineralization associated
decreases expression
ISO
T-2 Toxin results in decreased expression of ALPL protein
CTD
PMID:35289972
NCBI chr 5:155,234,770...155,289,785
Ensembl chr 5:155,234,775...155,254,167
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Angptl7
angiopoietin like 7
decreases expression
ISO
T-2 Toxin results in decreased expression of ANGPTL7 mRNA
CTD
PMID:31863870
NCBI chr 5:164,215,223...164,220,408
Ensembl chr 5:164,215,223...164,220,584
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Anln
anillin, actin binding protein
decreases expression
ISO
T-2 Toxin results in decreased expression of ANLN mRNA
CTD
PMID:34581912
NCBI chr 8:29,134,222...29,197,513
Ensembl chr 8:29,134,222...29,197,513
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Anp32b
acidic nuclear phosphoprotein 32 family member B
affects expression
EXP
T-2 Toxin affects the expression of ANP32B protein
CTD
PMID:26141394
NCBI chr 5:65,538,872...65,561,305
Ensembl chr 5:65,538,535...65,561,437
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Anxa1
annexin A1
decreases expression
ISO
T-2 Toxin results in decreased expression of ANXA1 protein
CTD
PMID:34581912
NCBI chr 1:227,287,713...227,306,739
Ensembl chr 1:227,287,717...227,306,831
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Anxa5
annexin A5
affects expression
EXP
T-2 Toxin affects the expression of ANXA5 protein
CTD
PMID:26141394
NCBI chr 2:121,242,133...121,272,935
Ensembl chr 2:121,242,136...121,281,400
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Apoe
apolipoprotein E
increases expression
EXP
T-2 Toxin results in increased expression of APOE mRNA
CTD
PMID:26141394
NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:88,481,385...88,485,855
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App
amyloid beta precursor protein
decreases expression
EXP
T-2 Toxin results in decreased expression of APP mRNA
CTD
PMID:26141394
NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971
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Aprt
adenine phosphoribosyl transferase
affects expression
EXP
T-2 Toxin affects the expression of APRT protein
CTD
PMID:26141394
NCBI chr19:67,534,737...67,537,027
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Ar
androgen receptor
multiple interactions
EXP
T-2 Toxin promotes the reaction [GABPA protein binds to AR]
CTD
PMID:36863559
NCBI chr X:67,135,317...67,304,476
Ensembl chr X:67,135,317...67,304,467
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Areg
amphiregulin
multiple interactions
ISO
T-2 Toxin inhibits the reaction [[CGA protein co-treated with FSHB protein] results in increased expression of AREG mRNA]
CTD
PMID:30951242
NCBI chr14:17,256,384...17,265,641
Ensembl chr14:17,256,384...17,265,641
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Arhgap18
Rho GTPase activating protein 18
decreases expression
EXP
T-2 Toxin results in decreased expression of ARHGAP18 mRNA
CTD
PMID:26141394
NCBI chr 1:18,403,531...18,637,306
Ensembl chr 1:20,222,954...20,456,670
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Arl5c
ARF like GTPase 5C
increases expression
EXP
T-2 Toxin results in increased expression of ARL5C mRNA
CTD
PMID:26141394
NCBI chr10:82,985,213...82,993,425
Ensembl chr10:83,481,540...83,488,406
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Arrb2
arrestin, beta 2
increases expression
ISO
T-2 Toxin results in increased expression of ARRB2 mRNA
CTD
PMID:34581912
NCBI chr10:55,645,539...55,653,485
Ensembl chr10:55,645,357...55,653,487
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Arsa
arylsulfatase A
decreases expression
EXP
T-2 Toxin results in decreased expression of ARSA mRNA
CTD
PMID:26141394
NCBI chr 7:122,422,971...122,426,971
Ensembl chr 7:122,422,982...122,428,401
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Asap3
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
decreases expression
ISO
T-2 Toxin results in decreased expression of ASAP3 mRNA
CTD
PMID:31863870
NCBI chr 5:148,433,382...148,476,027
Ensembl chr 5:153,716,988...153,757,787
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Asb14
ankyrin repeat and SOCS box-containing 14
increases expression
EXP
T-2 Toxin results in increased expression of ASB14 mRNA
CTD
PMID:26141394
NCBI chr16:2,095,567...2,123,259
Ensembl chr16:2,102,363...2,130,590
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Asb5
ankyrin repeat and SOCS box-containing 5
increases expression
EXP
T-2 Toxin results in increased expression of ASB5 mRNA
CTD
PMID:26141394
NCBI chr16:37,237,869...37,305,207
Ensembl chr16:43,970,940...44,010,437
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Asb6
ankyrin repeat and SOCS box-containing 6
increases expression
EXP
T-2 Toxin results in increased expression of ASB6 mRNA
CTD
PMID:26141394
NCBI chr 3:14,110,628...14,115,274
Ensembl chr 3:34,508,140...34,513,033
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Asns
asparagine synthetase (glutamine-hydrolyzing)
decreases expression
ISO
T-2 Toxin results in decreased expression of ASNS mRNA
CTD
PMID:31863870 PMID:34581912
NCBI chr 4:36,752,061...36,769,970
Ensembl chr 4:36,751,802...36,776,050
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Ass1
argininosuccinate synthase 1
decreases expression
ISO
T-2 Toxin results in decreased expression of ASS1 mRNA
CTD
PMID:31863870 PMID:34581912
NCBI chr 3:35,144,765...35,194,632
Ensembl chr 3:35,144,999...35,194,627
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Atf4
activating transcription factor 4
multiple interactions increases expression
ISO
salubrinal promotes the reaction [T-2 Toxin results in increased expression of ATF4 protein]
CTD
PMID:34673134
NCBI chr 7:113,684,681...113,686,739
Ensembl chr 7:113,684,681...113,686,739
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Atg12
autophagy related 12
increases expression
ISO
T-2 Toxin results in increased expression of ATG12 protein
CTD
PMID:26138683
NCBI chr18:41,638,841...41,649,311
Ensembl chr18:41,635,835...41,649,261
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Atg14
autophagy related 14
increases expression
ISO
T-2 Toxin results in increased expression of ATG14 mRNA
CTD
PMID:26138683
NCBI chr15:23,275,457...23,306,817
Ensembl chr15:23,275,457...23,306,815
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Atg3
autophagy related 3
increases expression multiple interactions
EXP ISO
T-2 Toxin results in increased expression of ATG3 protein T-2 Toxin results in increased expression of ATG3 mRNA; T-2 Toxin results in increased expression of ATG3 protein ATG3 protein affects the reaction [T-2 Toxin results in increased expression of TNF mRNA]; ATG3 protein inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; ATG3 protein inhibits the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; MIR155 mRNA inhibits the reaction [T-2 Toxin results in increased expression of ATG3 mRNA]; MIR155 mRNA inhibits the reaction [T-2 Toxin results in increased expression of ATG3 protein]
CTD
PMID:29870751 PMID:32240701
NCBI chr11:69,130,948...69,159,280
Ensembl chr11:69,121,952...69,159,280
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Atg5
autophagy related 5
affects expression multiple interactions increases expression
EXP ISO
T-2 Toxin affects the expression of ATG5 protein 3-methyladenine affects the reaction [T-2 Toxin affects the expression of ATG5 protein] T-2 Toxin results in increased expression of ATG5 protein
CTD
PMID:29413859 PMID:35289972 PMID:36402210
NCBI chr20:49,380,835...49,471,826
Ensembl chr20:49,380,813...49,471,821
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Atic
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
decreases expression
ISO
T-2 Toxin results in decreased expression of ATIC protein
CTD
PMID:34581912
NCBI chr 9:80,614,311...80,634,360
Ensembl chr 9:80,614,283...80,635,756
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Atm
ATM serine/threonine kinase
increases phosphorylation decreases expression
ISO
T-2 Toxin results in increased phosphorylation of ATM protein T-2 Toxin results in decreased expression of ATM mRNA
CTD
PMID:20150440 PMID:34581912
NCBI chr 8:62,724,939...62,829,040
Ensembl chr 8:62,727,291...62,828,629
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Atp11a
ATPase phospholipid transporting 11A
decreases expression
EXP
T-2 Toxin results in decreased expression of ATP11A mRNA
CTD
PMID:26141394
NCBI chr16:83,359,884...83,469,807
Ensembl chr16:83,359,884...83,469,767
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Atp1a1
ATPase Na+/K+ transporting subunit alpha 1
decreases expression
EXP
T-2 Toxin results in decreased expression of ATP1A1 mRNA
CTD
PMID:26141394
NCBI chr 2:191,709,311...191,737,414
Ensembl chr 2:191,709,311...191,737,425
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Atp5f1a
ATP synthase F1 subunit alpha
affects expression
EXP
T-2 Toxin affects the expression of ATP5F1A protein
CTD
PMID:26141394
NCBI chr18:73,567,537...73,575,473
Ensembl chr18:73,567,526...73,575,922
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Atp5f1b
ATP synthase F1 subunit beta
affects expression
EXP
T-2 Toxin affects the expression of ATP5F1B protein
CTD
PMID:26141394
NCBI chr 7:1,100,058...1,106,461
Ensembl chr 7:1,099,860...1,106,462
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Atp5pd
ATP synthase peripheral stalk subunit d
affects expression
EXP
T-2 Toxin affects the expression of ATP5PD protein
CTD
PMID:26141394
NCBI chr10:101,156,673...101,161,926
Ensembl chr10:101,156,673...101,162,954
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Atp6v1a
ATPase H+ transporting V1 subunit A
affects expression
EXP
T-2 Toxin affects the expression of ATP6V1A protein
CTD
PMID:26141394
NCBI chr11:70,066,800...70,120,603
Ensembl chr11:70,035,134...70,120,603
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Atp6v1b2
ATPase H+ transporting V1 subunit B2
affects expression
EXP
T-2 Toxin affects the expression of ATP6V1B2 protein
CTD
PMID:26141394
NCBI chr16:25,384,254...25,408,388
Ensembl chr16:25,384,257...25,408,839
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Atp8b2
ATPase phospholipid transporting 8B2
decreases expression
ISO
T-2 Toxin results in decreased expression of ATP8B2 mRNA
CTD
PMID:31863870
NCBI chr 2:177,676,205...177,699,575
Ensembl chr 2:177,676,208...177,699,575
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Aup1
AUP1, lipid droplet regulating VLDL assembly factor
increases expression
ISO
T-2 Toxin results in increased expression of AUP1 mRNA
CTD
PMID:31863870
NCBI chr 4:117,118,035...117,121,063
Ensembl chr 4:117,117,999...117,121,061
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Axl
Axl receptor tyrosine kinase
increases expression
ISO
T-2 Toxin results in increased expression of AXL mRNA
CTD
PMID:34581912
NCBI chr 1:90,392,864...90,424,123
Ensembl chr 1:90,392,864...90,424,009
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B2m
beta-2 microglobulin
increases expression
ISO
T-2 Toxin results in increased expression of B2M protein
CTD
PMID:33508416
NCBI chr 3:129,549,236...129,555,354
Ensembl chr 3:129,549,318...129,555,356
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Bag5
BAG cochaperone 5
increases expression
EXP
T-2 Toxin results in increased expression of BAG5 mRNA
CTD
PMID:26141394
NCBI chr 6:136,589,623...136,593,278
Ensembl chr 6:136,584,741...136,598,492
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Bak1
BCL2-antagonist/killer 1
increases expression
ISO
T-2 Toxin results in increased expression of BAK1 mRNA
CTD
PMID:34581912
NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,102,335...5,110,974
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Bax
BCL2 associated X, apoptosis regulator
affects localization decreases expression affects expression increases expression multiple interactions
ISO EXP
T-2 Toxin affects the localization of BAX protein T-2 Toxin results in decreased expression of BAX protein T-2 Toxin affects the expression of BAX protein T-2 Toxin results in increased expression of BAX mRNA; T-2 Toxin results in increased expression of BAX protein Selenium inhibits the reaction [T-2 Toxin results in increased expression of BAX mRNA]
CTD
PMID:16307838 PMID:19524637 PMID:19541794 PMID:21296132 PMID:26138683 PMID:26314264 PMID:28697680 PMID:29413859 PMID:29432840 PMID:29870751 PMID:33508416 PMID:35289972 More...
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
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Bbc3
Bcl-2 binding component 3
increases expression
EXP
T-2 Toxin results in increased expression of BBC3 mRNA
CTD
PMID:26141394
NCBI chr 1:86,141,450...86,150,666
Ensembl chr 1:86,141,603...86,150,666
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Bcat1
branched chain amino acid transaminase 1
decreases expression
ISO
T-2 Toxin results in decreased expression of BCAT1 mRNA
CTD
PMID:34581912
NCBI chr 4:179,695,662...179,777,973
Ensembl chr 4:179,695,662...179,777,288
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Bccip
BRCA2 and CDKN1A interacting protein
increases expression
ISO
T-2 Toxin results in increased expression of BCCIP mRNA
CTD
PMID:31863870
NCBI chr 1:188,512,544...188,524,957
Ensembl chr 1:197,942,190...197,956,378
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Bcl2
BCL2, apoptosis regulator
increases expression increases activity decreases expression
EXP ISO
T-2 Toxin results in increased expression of BCL2 mRNA; T-2 Toxin results in increased expression of BCL2 protein T-2 Toxin results in increased activity of BCL2 protein T-2 Toxin results in decreased expression of BCL2 mRNA; T-2 Toxin results in decreased expression of BCL2 protein
CTD
PMID:19524637 PMID:21296132 PMID:28697680 PMID:29870751 PMID:33508416 PMID:34581912 PMID:35289972 More...
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
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Bcl2l1
Bcl2-like 1
decreases expression affects expression
ISO EXP
T-2 Toxin results in decreased expression of BCL2L1 mRNA; T-2 Toxin results in decreased expression of BCL2L1 protein T-2 Toxin affects the expression of BCL2L1 protein
CTD
PMID:29413859 PMID:29432840
NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907 Ensembl chr 1:161,745,540...161,764,907
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Becn1
beclin 1
increases expression multiple interactions affects expression
EXP ISO
T-2 Toxin results in increased expression of BECN1 mRNA 3-methyladenine affects the reaction [T-2 Toxin affects the expression of BECN1 protein] T-2 Toxin results in increased expression of BECN1 protein 3-methyladenine inhibits the reaction [T-2 Toxin results in increased expression of BECN1 mRNA]; Selenium deficiency inhibits the reaction [T-2 Toxin results in increased expression of BECN1 mRNA]; Sirolimus promotes the reaction [T-2 Toxin results in increased expression of BECN1 mRNA]
CTD
PMID:30629952 PMID:35289972 PMID:36402210
NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,731,650...86,747,002
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Bglap
bone gamma-carboxyglutamate protein
decreases expression
ISO
T-2 Toxin results in decreased expression of BGLAP protein
CTD
PMID:35289972
NCBI chr 2:176,136,341...176,137,318
Ensembl chr 2:176,136,341...176,137,318
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Bid
BH3 interacting domain death agonist
decreases expression
ISO
T-2 Toxin results in decreased expression of BID protein
CTD
PMID:29432840
NCBI chr 4:155,785,366...155,808,775
Ensembl chr 4:155,785,377...155,808,275
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Bnip3l
BCL2 interacting protein 3 like
increases expression
EXP
T-2 Toxin results in increased expression of BNIP3L mRNA
CTD
PMID:29870751
NCBI chr15:45,350,081...45,373,213
Ensembl chr15:45,334,537...45,373,282
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Bop1
BOP1 ribosomal biogenesis factor
increases expression
ISO
T-2 Toxin results in increased expression of BOP1 mRNA
CTD
PMID:34581912
NCBI chr 7:110,052,716...110,076,529
Ensembl chr 7:110,052,720...110,076,529
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Bpnt1
3'(2'), 5'-bisphosphate nucleotidase 1
affects expression
EXP
T-2 Toxin affects the expression of BPNT1 protein
CTD
PMID:26141394
NCBI chr13:96,865,634...96,893,506
Ensembl chr13:99,400,115...99,425,053
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Brip1
BRCA1 interacting DNA helicase 1
decreases expression
ISO
T-2 Toxin results in decreased expression of BRIP1 mRNA
CTD
PMID:34581912
NCBI chr10:71,402,035...71,528,083
Ensembl chr10:71,401,151...71,575,206
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Btg2
BTG anti-proliferation factor 2
increases expression multiple interactions
ISO
T-2 Toxin results in increased expression of BTG2 mRNA; T-2 Toxin results in increased expression of BTG2 protein BTG2 protein affects the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; BTG2 protein affects the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; BTG2 protein affects the reaction [T-2 Toxin results in increased expression of TNF mRNA]; BTG2 protein affects the reaction [T-2 Toxin results in increased phosphorylation of AKT1 protein]; BTG2 protein affects the reaction [T-2 Toxin results in increased phosphorylation of NFKBIA protein]; BTG2 protein affects the reaction [T-2 Toxin results in increased phosphorylation of RELA protein]; Minocycline inhibits the reaction [T-2 Toxin results in increased expression of BTG2 mRNA]; Minocycline inhibits the reaction [T-2 Toxin results in increased expression of BTG2 protein]
CTD
PMID:39147216
NCBI chr13:48,083,931...48,087,690
Ensembl chr13:48,083,931...48,087,690
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Bud23
BUD23, rRNA methyltransferase and ribosome maturation factor
increases expression
ISO
T-2 Toxin results in increased expression of BUD23 mRNA
CTD
PMID:31863870
NCBI chr12:21,629,551...21,640,758
Ensembl chr12:27,265,521...27,277,297
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C5
complement C5
increases expression
ISO
T-2 Toxin results in increased expression of C5 mRNA
CTD
PMID:34581912
NCBI chr 3:38,668,174...38,759,468
Ensembl chr 3:38,668,174...38,759,468
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Calm1
calmodulin 1
affects expression
EXP
T-2 Toxin affects the expression of CALM1 protein
CTD
PMID:26141394
NCBI chr 6:125,217,191...125,227,855
Ensembl chr 6:125,217,246...125,225,381
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Camp
cathelicidin antimicrobial peptide
multiple interactions
EXP
[Selenium deficiency co-treated with T-2 Toxin] results in decreased expression of CAMP mRNA
CTD
PMID:38796086
NCBI chr 8:118,720,184...118,721,998
Ensembl chr 8:118,720,184...118,721,998
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Capns1
calpain, small subunit 1
affects expression
EXP
T-2 Toxin affects the expression of CAPNS1 protein
CTD
PMID:26141394
NCBI chr 1:94,572,083...94,582,332
Ensembl chr 1:94,572,083...94,583,368
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Cars1
cysteinyl-tRNA synthetase 1
decreases expression
EXP ISO
T-2 Toxin results in decreased expression of CARS1 mRNA
CTD
PMID:26141394 PMID:34581912
NCBI chr 1:208,183,092...208,225,425
Ensembl chr 1:208,182,788...208,225,407
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Casp12
caspase 12
multiple interactions increases expression
ISO EXP
salubrinal inhibits the reaction [T-2 Toxin results in increased expression of CASP12 mRNA] T-2 Toxin results in increased expression of CASP12 mRNA; T-2 Toxin results in increased expression of CASP12 protein salubrinal inhibits the reaction [T-2 Toxin results in increased expression of CASP12 mRNA]; salubrinal inhibits the reaction [T-2 Toxin results in increased expression of CASP12 protein]
CTD
PMID:34673134
NCBI chr 8:10,927,188...10,954,442
Ensembl chr 8:10,926,994...10,954,442
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Casp3
caspase 3
multiple interactions affects expression increases activity increases expression
EXP ISO
3-methyladenine promotes the reaction [T-2 Toxin results in increased expression of CASP3 protein modified form]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [T-2 Toxin results in increased activity of CASP3 protein]; Selenium deficiency promotes the reaction [T-2 Toxin results in increased expression of CASP3 protein modified form]; Sirolimus inhibits the reaction [T-2 Toxin results in increased expression of CASP3 protein modified form]; T-2 Toxin results in increased cleavage of and results in increased activity of CASP3 protein T-2 Toxin affects the expression of CASP3 protein Acetylcysteine inhibits the reaction [T-2 Toxin results in increased activity of CASP3 protein]; brusatol promotes the reaction [T-2 Toxin results in increased activity of CASP3 protein]; T-2 Toxin results in increased expression of and results in increased activity of CASP3 protein; zinc protoporphyrin promotes the reaction [T-2 Toxin results in increased activity of CASP3 protein] T-2 Toxin results in increased expression of CASP3 mRNA; T-2 Toxin results in increased expression of CASP3 protein; T-2 Toxin results in increased expression of CASP3 protein modified form
CTD
PMID:19428930 PMID:19524637 PMID:19541794 PMID:21295106 PMID:21296132 PMID:26138683 PMID:28697680 PMID:29413859 PMID:29432840 PMID:29567467 PMID:29870751 PMID:30629952 PMID:33508416 PMID:35289972 More...
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
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Casp7
caspase 7
increases activity
ISO
T-2 Toxin results in increased activity of CASP7 protein
CTD
PMID:19524637
NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:265,442,676...265,482,512
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Casp8
caspase 8
increases expression multiple interactions increases activity
EXP ISO
T-2 Toxin results in increased expression of CASP8 mRNA Acetylcysteine inhibits the reaction [T-2 Toxin results in increased activity of CASP8 protein]
CTD
PMID:26141394 PMID:29432840 PMID:29567467 PMID:29870751
NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699
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Casp9
caspase 9
increases activity multiple interactions increases expression
ISO EXP
T-2 Toxin results in increased activity of CASP9 protein Acetylcysteine inhibits the reaction [T-2 Toxin results in increased activity of CASP9 protein]; brusatol promotes the reaction [T-2 Toxin results in increased activity of CASP9 protein]; zinc protoporphyrin promotes the reaction [T-2 Toxin results in increased activity of CASP9 protein] T-2 Toxin results in increased expression of CASP9 mRNA 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [T-2 Toxin results in increased activity of CASP9 protein]; T-2 Toxin results in increased cleavage of and results in increased activity of CASP9 protein
CTD
PMID:19524637 PMID:21296132 PMID:29432840 PMID:29567467 PMID:33508416 PMID:35289972 More...
Ensembl chr 5:159,391,188...159,409,648
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Cat
catalase
increases activity decreases expression increases expression decreases activity multiple interactions
ISO EXP
T-2 Toxin results in increased activity of CAT protein T-2 Toxin results in decreased expression of CAT mRNA T-2 Toxin results in increased expression of CAT mRNA T-2 Toxin results in decreased activity of CAT protein T-2 Toxin affects the expression of and affects the activity of CAT protein
CTD
PMID:19526462 PMID:21112371 PMID:23929680 PMID:27842451 PMID:29432840 PMID:29870751 PMID:30091165 PMID:33508416 PMID:34581912 More...
NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
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Cbr1
carbonyl reductase 1
affects expression
EXP
T-2 Toxin affects the expression of CBR1 protein
CTD
PMID:26141394
NCBI chr11:46,346,405...46,348,815
Ensembl chr11:46,378,411...46,381,104 Ensembl chr11:46,378,411...46,381,104
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Ccdc137
coiled-coil domain containing 137
increases expression
ISO
T-2 Toxin results in increased expression of CCDC137 mRNA
CTD
PMID:31863870
NCBI chr10:106,229,099...106,235,502
Ensembl chr10:106,229,099...106,235,502
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Ccdc34
coiled-coil domain containing 34
increases expression
ISO
T-2 Toxin results in increased expression of CCDC34 mRNA
CTD
PMID:31863870
NCBI chr 3:117,007,652...117,042,885
Ensembl chr 3:117,005,760...117,042,226
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Ccn3
cellular communication network factor 3
decreases expression
ISO
T-2 Toxin results in decreased expression of CCN3 mRNA
CTD
PMID:31863870
NCBI chr 7:86,094,000...86,101,022
Ensembl chr 7:87,982,216...87,994,581
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Ccnb1ip1
cyclin B1 interacting protein 1
increases expression
EXP
T-2 Toxin results in increased expression of CCNB1IP1 mRNA
CTD
PMID:26141394
NCBI chr15:26,488,462...26,504,167
Ensembl chr15:26,488,465...26,502,028
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Ccnb2
cyclin B2
decreases expression
ISO
T-2 Toxin results in decreased expression of CCNB2 mRNA
CTD
PMID:34581912
NCBI chr 8:79,968,459...79,981,717
Ensembl chr 8:79,968,465...79,981,682
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Ccnd1
cyclin D1
decreases expression
ISO EXP
T-2 Toxin results in decreased expression of CCND1 mRNA T-2 Toxin results in decreased expression of CCND1 mRNA; T-2 Toxin results in decreased expression of CCND1 protein
CTD
PMID:22454431 PMID:29567467 PMID:35289972
NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810
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Ccng1
cyclin G1
decreases expression
ISO
T-2 Toxin results in decreased expression of CCNG1 mRNA
CTD
PMID:34581912
NCBI chr10:25,678,503...25,684,876
Ensembl chr10:25,677,885...25,683,766
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Ccng2
cyclin G2
decreases expression
ISO
T-2 Toxin results in decreased expression of CCNG2 mRNA
CTD
PMID:34581912
NCBI chr14:15,088,694...15,097,190
Ensembl chr14:15,088,695...15,096,206
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Cct2
chaperonin containing TCP1 subunit 2
decreases expression
ISO
T-2 Toxin results in decreased expression of CCT2 protein
CTD
PMID:34581912
NCBI chr 7:54,578,654...54,591,428
Ensembl chr 7:54,578,663...54,592,977
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Cd24
CD24 molecule
decreases expression
ISO
T-2 Toxin results in decreased expression of CD24 mRNA
CTD
PMID:31863870
NCBI chr20:48,655,549...48,661,786
Ensembl chr20:48,655,805...48,661,785
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Cd274
CD274 molecule
increases expression
ISO
T-2 Toxin results in increased expression of CD274 protein
CTD
PMID:36115646
NCBI chr 1:236,526,215...236,549,956
Ensembl chr 1:236,496,463...236,549,951
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Cd40
CD40 molecule
increases expression
ISO
T-2 Toxin results in increased expression of CD40 mRNA
CTD
PMID:36775139
NCBI chr 3:174,209,113...174,224,592
Ensembl chr 3:174,209,719...174,224,847
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Cd44
CD44 molecule
multiple interactions decreases expression
ISO
Selenium inhibits the reaction [T-2 Toxin results in decreased expression of CD44 protein] T-2 Toxin results in decreased expression of CD44 mRNA; T-2 Toxin results in decreased expression of CD44 protein
CTD
PMID:18196609
NCBI chr 3:109,610,824...109,699,776
Ensembl chr 3:109,612,054...109,699,424
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Cd55
CD55 molecule (Cromer blood group)
decreases expression
ISO
T-2 Toxin results in decreased expression of CD55 mRNA
CTD
PMID:31863870
NCBI chr13:44,409,574...44,438,913
Ensembl chr13:44,409,587...44,438,107
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Cdc42bpa
CDC42 binding protein kinase alpha
decreases expression
ISO
T-2 Toxin results in decreased expression of CDC42BPA mRNA
CTD
PMID:34581912
NCBI chr13:94,215,359...94,435,681
Ensembl chr13:94,215,959...94,435,681
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Cdca5
cell division cycle associated 5
increases expression
EXP
T-2 Toxin results in increased expression of CDCA5 mRNA
CTD
PMID:26141394
NCBI chr 1:212,807,863...212,821,313
Ensembl chr 1:212,804,014...212,821,309
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Cdca7
cell division cycle associated 7
increases expression
EXP
T-2 Toxin results in increased expression of CDCA7 mRNA
CTD
PMID:26141394
NCBI chr 3:77,730,315...77,740,950
Ensembl chr 3:77,729,970...77,740,947
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Cdca8
cell division cycle associated 8
increases expression
EXP
T-2 Toxin results in increased expression of CDCA8 mRNA
CTD
PMID:26141394
NCBI chr 5:142,461,082...142,483,336
Ensembl chr 5:142,461,084...142,483,283
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Cdk4
cyclin-dependent kinase 4
decreases expression
EXP
T-2 Toxin results in decreased expression of CDK4 mRNA; T-2 Toxin results in decreased expression of CDK4 protein
CTD
PMID:29567467
NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:64,771,147...64,775,163
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Cdk5
cyclin-dependent kinase 5
increases expression decreases expression
ISO
T-2 Toxin results in increased expression of CDK5 mRNA T-2 Toxin results in decreased expression of CDK5 mRNA
CTD
PMID:34581912 PMID:39147216
NCBI chr 4:11,647,098...11,651,606
Ensembl chr 4:11,647,141...11,652,777
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Cdk5rap1
CDK5 regulatory subunit associated protein 1
increases expression
EXP
T-2 Toxin results in increased expression of CDK5RAP1 mRNA
CTD
PMID:26141394
NCBI chr 3:163,189,435...163,333,003
Ensembl chr 3:163,191,056...163,332,908
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Cdkn1a
cyclin-dependent kinase inhibitor 1A
increases expression
ISO EXP
T-2 Toxin results in increased expression of CDKN1A mRNA T-2 Toxin results in increased expression of CDKN1A mRNA; T-2 Toxin results in increased expression of CDKN1A protein
CTD
PMID:22454431 PMID:29567467
NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
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Cdkn2a
cyclin-dependent kinase inhibitor 2A
increases expression
EXP
T-2 Toxin results in increased expression of CDKN2A mRNA; T-2 Toxin results in increased expression of CDKN2A protein
CTD
PMID:29567467
NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:109,100,772...109,119,248
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Cdkn3
cyclin-dependent kinase inhibitor 3
increases expression
ISO
T-2 Toxin results in increased expression of CDKN3 mRNA
CTD
PMID:31863870
NCBI chr15:22,502,299...22,513,725
Ensembl chr15:22,502,382...22,513,722
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Cenpe
centromere protein E
decreases expression
ISO
T-2 Toxin results in decreased expression of CENPE mRNA
CTD
PMID:34581912
NCBI chr 2:226,310,970...226,369,636
Ensembl chr 2:226,300,798...226,369,636
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Cenpf
centromere protein F
decreases expression
ISO
T-2 Toxin results in decreased expression of CENPF mRNA
CTD
PMID:34581912
NCBI chr13:103,715,344...103,760,931
Ensembl chr13:103,715,344...103,760,886
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Cep135
centrosomal protein 135
decreases expression
ISO
T-2 Toxin results in decreased expression of CEP135 mRNA
CTD
PMID:34581912
NCBI chr14:31,884,774...31,950,050
Ensembl chr14:31,884,781...31,950,050
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Cfap96
cilia and flagella associated protein 96
increases expression
ISO
T-2 Toxin results in increased expression of CFAP96 mRNA
CTD
PMID:31863870
NCBI chr16:46,291,075...46,315,616
Ensembl chr16:53,023,878...53,048,965
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Cfl1
cofilin 1
affects expression
EXP
T-2 Toxin affects the expression of CFL1 protein
CTD
PMID:26141394
NCBI chr 1:212,227,124...212,230,656
Ensembl chr 1:212,226,121...212,231,353
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Cga
glycoprotein hormones, alpha polypeptide
multiple interactions
ISO
[T-2 Toxin co-treated with CGA protein] results in decreased activity of CYP11A1 protein; [T-2 Toxin co-treated with CGA protein] results in decreased activity of CYP17A1 protein; [T-2 Toxin co-treated with CGA protein] results in decreased activity of STAR protein; [T-2 Toxin co-treated with CGA protein] results in decreased expression of CYP11A1 mRNA; [T-2 Toxin co-treated with CGA protein] results in decreased expression of STAR mRNA T-2 Toxin inhibits the reaction [[CGA protein co-treated with FSHB protein] results in increased expression of AREG mRNA]; T-2 Toxin inhibits the reaction [[CGA protein co-treated with FSHB protein] results in increased expression of EREG mRNA]; T-2 Toxin inhibits the reaction [[CGA protein co-treated with FSHB protein] results in increased expression of PGR mRNA]
CTD
PMID:25962641 PMID:30951242
NCBI chr 5:54,283,109...54,295,464
Ensembl chr 5:54,235,019...54,295,464
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Cgrrf1
cell growth regulator with ring finger domain 1
increases expression
EXP
T-2 Toxin results in increased expression of CGRRF1 mRNA
CTD
PMID:26141394
NCBI chr15:22,560,902...22,588,815
Ensembl chr15:22,568,332...22,588,811
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Chek2
checkpoint kinase 2
multiple interactions increases activity
ISO
2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [T-2 Toxin results in increased activity of CHEK2 protein]
CTD
PMID:20150440
NCBI chr12:51,448,838...51,481,159
Ensembl chr12:51,449,140...51,480,667
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Chpf
chondroitin polymerizing factor
decreases expression
ISO
T-2 Toxin results in decreased expression of CHPF mRNA
CTD
PMID:31863870
NCBI chr 9:76,963,178...76,967,878
Ensembl chr 9:84,411,829...84,416,523
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Chrna4
cholinergic receptor nicotinic alpha 4 subunit
decreases expression
ISO
T-2 Toxin results in decreased expression of CHRNA4 mRNA
CTD
PMID:26314264
NCBI chr 3:188,506,802...188,535,558
Ensembl chr 3:188,501,209...188,535,105
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Chrnb2
cholinergic receptor nicotinic beta 2 subunit
decreases expression
ISO
T-2 Toxin results in decreased expression of CHRNB2 mRNA
CTD
PMID:26314264
NCBI chr 2:177,479,091...177,487,306
Ensembl chr 2:177,479,091...177,491,326
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Ciita
class II, major histocompatibility complex, transactivator
increases expression
ISO
T-2 Toxin results in increased expression of CIITA mRNA
CTD
PMID:36775139
NCBI chr10:5,646,854...5,694,393
Ensembl chr10:5,647,085...5,694,342
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Cit
citron rho-interacting serine/threonine kinase
decreases expression
ISO
T-2 Toxin results in decreased expression of CIT mRNA
CTD
PMID:34581912
NCBI chr12:46,263,881...46,425,642
Ensembl chr12:46,266,369...46,424,656
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Ckb
creatine kinase B
affects expression
EXP
T-2 Toxin affects the expression of CKB protein
CTD
PMID:26141394
NCBI chr 6:136,550,583...136,553,464
Ensembl chr 6:136,549,844...136,553,478
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Ckmt2
creatine kinase, mitochondrial 2
decreases expression
EXP
T-2 Toxin results in decreased expression of CKMT2 mRNA
CTD
PMID:26141394
NCBI chr 2:24,815,008...24,845,511
Ensembl chr 2:24,815,008...24,845,511
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Cldn3
claudin 3
multiple interactions decreases expression
ISO
illite inhibits the reaction [T-2 Toxin results in decreased expression of CLDN3 mRNA]
CTD
PMID:27153755
NCBI chr12:27,345,075...27,346,547
Ensembl chr12:27,345,076...27,348,841
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Cldn4
claudin 4
multiple interactions decreases expression
ISO
illite inhibits the reaction [T-2 Toxin results in decreased expression of CLDN4 mRNA]
CTD
PMID:27153755
NCBI chr12:27,388,160...27,389,958
Ensembl chr12:27,387,981...27,389,958
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Clic1
chloride intracellular channel 1
affects expression
EXP
T-2 Toxin affects the expression of CLIC1 protein
CTD
PMID:26141394
NCBI chr20:3,769,522...3,778,367
Ensembl chr20:3,769,527...3,778,367
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Cln8
CLN8, transmembrane ER and ERGIC protein
increases expression
ISO
T-2 Toxin results in increased expression of CLN8 mRNA
CTD
PMID:34581912
NCBI chr16:81,451,941...81,462,046
Ensembl chr16:81,451,944...81,461,832
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Clu
clusterin
decreases expression increases expression
ISO
T-2 Toxin results in decreased expression of CLU mRNA T-2 Toxin results in increased expression of CLU mRNA
CTD
PMID:31863870 PMID:34581912
NCBI chr15:44,336,619...44,375,861
Ensembl chr15:44,359,914...44,375,860
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Cnpy2
canopy FGF signaling regulator 2
affects expression
EXP
T-2 Toxin affects the expression of CNPY2 protein
CTD
PMID:26141394
NCBI chr 7:1,332,293...1,338,081
Ensembl chr 7:1,334,335...1,340,333
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Cntf
ciliary neurotrophic factor
increases expression
EXP
T-2 Toxin results in increased expression of CNTF mRNA
CTD
PMID:26141394
NCBI chr 1:219,312,512...219,314,535
Ensembl chr 1:219,312,512...219,314,488
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Coa5
cytochrome C oxidase assembly factor 5
multiple interactions increases expression
EXP
GABPA promotes the reaction [T-2 Toxin results in increased expression of COA5 mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to COA5]
CTD
PMID:36863559
NCBI chr 9:47,147,267...47,160,724
Ensembl chr 9:47,147,267...47,160,672
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Col10a1
collagen type X alpha 1 chain
decreases expression
ISO
T-2 Toxin results in decreased expression of COL10A1 mRNA
CTD
PMID:22800716
NCBI chr20:39,737,536...39,744,518
Ensembl chr20:39,716,822...39,751,440
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Col11a1
collagen type XI alpha 1 chain
decreases expression
ISO
T-2 Toxin results in decreased expression of COL11A1 mRNA
CTD
PMID:31863870
NCBI chr 2:201,820,715...202,013,853
Ensembl chr 2:204,509,136...204,702,264
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Col15a1
collagen type XV alpha 1 chain
decreases expression
ISO
T-2 Toxin results in decreased expression of COL15A1 mRNA
CTD
PMID:31863870
NCBI chr 5:66,297,546...66,403,172
Ensembl chr 5:66,297,461...66,403,170
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Col1a1
collagen type I alpha 1 chain
decreases expression
ISO
T-2 Toxin results in decreased expression of COL1A1 mRNA
CTD
PMID:22800716 PMID:35289972
NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460
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Col1a2
collagen type I alpha 2 chain
multiple interactions decreases expression
ISO
3-methyladenine promotes the reaction [T-2 Toxin results in decreased expression of COL1A2 protein]
CTD
PMID:36402210
NCBI chr 4:33,518,557...33,553,484
Ensembl chr 4:33,518,420...33,553,995
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Col2a1
collagen type II alpha 1 chain
decreases expression multiple interactions
ISO
T-2 Toxin results in decreased expression of COL2A1 mRNA; T-2 Toxin results in decreased expression of COL2A1 protein MLKL protein affects the reaction [T-2 Toxin results in decreased expression of COL2A1 protein]
CTD
PMID:22800716 PMID:34673134 PMID:39966150
NCBI chr 7:130,977,561...131,006,627
Ensembl chr 7:130,977,561...131,006,627
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Col9a1
collagen type IX alpha 1 chain
decreases expression
ISO
T-2 Toxin results in decreased expression of COL9A1 mRNA
CTD
PMID:22800716
NCBI chr 9:34,081,364...34,164,552
Ensembl chr 9:34,003,905...34,164,543
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Colgalt2
collagen beta(1-O)galactosyltransferase 2
decreases expression
ISO
T-2 Toxin results in decreased expression of COLGALT2 mRNA
CTD
PMID:34581912
NCBI chr13:64,523,641...64,628,295
Ensembl chr13:67,073,551...67,178,194
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Cope
COPI coat complex subunit epsilon
affects expression
EXP
T-2 Toxin affects the expression of COPE protein
CTD
PMID:26141394
NCBI chr16:19,114,871...19,125,076
Ensembl chr16:19,148,832...19,159,212
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Copz1
COPI coat complex subunit zeta 1
increases expression
ISO
T-2 Toxin results in increased expression of COPZ1 mRNA
CTD
PMID:31863870
NCBI chr 7:136,287,696...136,314,131
Ensembl chr 7:136,288,032...136,314,135
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Coq5
coenzyme Q5, methyltransferase
increases expression
ISO
T-2 Toxin results in increased expression of COQ5 mRNA
CTD
PMID:31863870
NCBI chr12:46,977,632...46,994,575
Ensembl chr12:46,977,632...46,994,712
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Coro1c
coronin 1C
increases expression
ISO
T-2 Toxin results in increased expression of CORO1C mRNA
CTD
PMID:31863870
NCBI chr12:48,373,573...48,445,718
Ensembl chr12:48,373,597...48,445,716
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Coro2b
coronin 2B
decreases expression
ISO
T-2 Toxin results in decreased expression of CORO2B mRNA
CTD
PMID:31863870
NCBI chr 8:71,802,329...71,912,739
Ensembl chr 8:71,802,329...71,912,739
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Cox15
cytochrome c oxidase assembly homolog COX15
increases expression
ISO
T-2 Toxin results in increased expression of COX15 mRNA
CTD
PMID:34581912
NCBI chr 1:252,554,811...252,571,471
Ensembl chr 1:252,554,811...252,571,471
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Cox19
cytochrome c oxidase assembly factor COX19
increases expression
ISO
T-2 Toxin results in increased expression of COX19 mRNA
CTD
PMID:31863870
NCBI chr12:15,303,535...15,313,014
Ensembl chr12:20,417,341...20,426,868
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Cox4i1
cytochrome c oxidase subunit 4i1
multiple interactions decreases expression
ISO
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [T-2 Toxin results in decreased expression of COX4I1 protein]
CTD
PMID:27363784
NCBI chr19:48,721,680...48,727,920
Ensembl chr19:65,630,432...65,636,624
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Cox6c
cytochrome c oxidase subunit 6C
affects expression
EXP
T-2 Toxin affects the expression of COX6C protein
CTD
PMID:26141394
NCBI chr 7:69,014,410...69,027,145
Ensembl chr 7:69,014,417...69,027,166
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Cox6c-ps1
cytochrome c oxidase subunit VIc, pseudogene
decreases expression
EXP
T-2 Toxin results in decreased expression of COX6C-PS1 mRNA
CTD
PMID:26141394
NCBI chr19:52,192,612...52,193,470
Ensembl chr19:69,090,047...69,090,905
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Cpap
centrosome assembly and centriole elongation protein
decreases expression
ISO
T-2 Toxin results in decreased expression of CPAP mRNA
CTD
PMID:34581912
NCBI chr15:34,742,838...34,806,020
Ensembl chr15:34,742,838...34,802,421
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Creb1
cAMP responsive element binding protein 1
affects localization multiple interactions
EXP
T-2 Toxin affects the localization of CREB1 protein modified form T-2 Toxin promotes the reaction [CREB1 protein binds to AKNA promoter]
CTD
PMID:29079362
NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:73,397,306...73,466,339
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Creb3l1
cAMP responsive element binding protein 3-like 1
decreases expression
EXP
T-2 Toxin results in decreased expression of CREB3L1 mRNA
CTD
PMID:26141394
NCBI chr 3:98,408,240...98,449,104
Ensembl chr 3:98,408,058...98,449,104
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Creb5
cAMP responsive element binding protein 5
increases expression
ISO
T-2 Toxin results in increased expression of CREB5 mRNA
CTD
PMID:31863870 PMID:34581912
NCBI chr 4:83,723,587...84,124,786
Ensembl chr 4:83,723,194...84,120,793
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Crem
cAMP responsive element modulator
decreases expression
EXP
T-2 Toxin results in decreased expression of CREM mRNA
CTD
PMID:26141394
NCBI chr17:58,932,011...59,001,160
Ensembl chr17:58,934,147...59,001,160
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Crtc3
CREB regulated transcription coactivator 3
decreases expression
EXP
T-2 Toxin results in decreased expression of CRTC3 mRNA
CTD
PMID:26141394
NCBI chr 1:143,962,038...144,064,324
Ensembl chr 1:143,962,038...144,064,288
G
Cryab
crystallin, alpha B
increases expression
ISO
T-2 Toxin results in increased expression of CRYAB mRNA
CTD
PMID:34581912
NCBI chr 8:59,989,885...59,995,532
Ensembl chr 8:59,989,814...59,995,528
G
Cs
citrate synthase
decreases expression
ISO
T-2 Toxin results in decreased expression of CS protein
CTD
PMID:34581912
NCBI chr 7:1,348,389...1,374,624
Ensembl chr 7:1,342,942...1,375,938
G
Csf1
colony stimulating factor 1
increases expression
EXP ISO
T-2 Toxin results in increased expression of CSF1 mRNA
CTD
PMID:26141394 PMID:34581912
NCBI chr 2:198,065,400...198,084,774
Ensembl chr 2:198,065,405...198,084,468
G
Csrnp1
cysteine and serine rich nuclear protein 1
increases expression
ISO
T-2 Toxin results in increased expression of CSRNP1 mRNA
CTD
PMID:34581912
NCBI chr 8:128,582,364...128,594,163
Ensembl chr 8:128,582,365...128,588,469
G
Cst3
cystatin C
increases expression
ISO
T-2 Toxin results in increased expression of CST3 protein
CTD
PMID:33508416
NCBI chr 3:156,790,061...156,794,116
Ensembl chr 3:156,790,079...156,793,937
G
Cth
cystathionine gamma-lyase
decreases expression
ISO
T-2 Toxin results in decreased expression of CTH mRNA
CTD
PMID:34581912
NCBI chr 2:249,634,731...249,661,066
Ensembl chr 2:249,634,731...249,661,066
G
Ctnnb1
catenin beta 1
decreases expression multiple interactions
ISO
T-2 Toxin results in decreased expression of CTNNB1 mRNA; T-2 Toxin results in decreased expression of CTNNB1 protein 3-methyladenine promotes the reaction [T-2 Toxin results in decreased expression of CTNNB1 protein]
CTD
PMID:35289972 PMID:36402210
NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662
G
Ctrb1
chymotrypsinogen B1
affects expression
EXP
T-2 Toxin affects the expression of CTRB1 protein
CTD
PMID:26141394
NCBI chr19:39,652,931...39,657,689
Ensembl chr19:56,562,220...56,566,978
G
Ctsa
cathepsin A
decreases expression
ISO
T-2 Toxin results in decreased expression of CTSA mRNA
CTD
PMID:31863870
NCBI chr 3:173,988,443...173,994,320
Ensembl chr 3:173,988,460...173,995,539
G
Cwc27
CWC27 spliceosome associated cyclophilin
increases expression
ISO
T-2 Toxin results in increased expression of CWC27 mRNA
CTD
PMID:31863870
NCBI chr 2:37,498,462...37,709,691
Ensembl chr 2:37,498,468...37,709,355
G
Cyb5r1
cytochrome b5 reductase 1
decreases expression
EXP
T-2 Toxin results in decreased expression of CYB5R1 mRNA
CTD
PMID:26141394
NCBI chr13:48,401,061...48,407,466
Ensembl chr13:48,399,106...48,407,465
G
Cyc1
cytochrome c-1
increases expression
EXP
T-2 Toxin results in increased expression of CYC1 mRNA
CTD
PMID:29870751
NCBI chr 7:109,947,750...109,950,142
Ensembl chr 7:109,947,766...109,950,657
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Cycs
cytochrome c, somatic
affects localization
ISO
T-2 Toxin affects the localization of CYCS protein
CTD
PMID:19541794
NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:80,982,668...80,984,816 Ensembl chr18:80,982,668...80,984,816
G
Cyfip1
cytoplasmic FMR1 interacting protein 1
decreases expression
EXP
T-2 Toxin results in decreased expression of CYFIP1 mRNA
CTD
PMID:26141394
NCBI chr 1:115,842,754...115,935,163
Ensembl chr 1:115,846,661...115,951,292
G
Cyp11a1
cytochrome P450, family 11, subfamily a, polypeptide 1
multiple interactions increases expression decreases expression
ISO EXP
[T-2 Toxin co-treated with CGA protein] results in decreased activity of CYP11A1 protein; [T-2 Toxin co-treated with CGA protein] results in decreased expression of CYP11A1 mRNA T-2 Toxin results in increased expression of CYP11A1 mRNA T-2 Toxin results in decreased expression of CYP11A1 mRNA
CTD
PMID:25962641 PMID:26141394 PMID:34581912
NCBI chr 8:67,318,665...67,330,196
Ensembl chr 8:67,270,556...67,330,196
G
Cyp17a1
cytochrome P450, family 17, subfamily a, polypeptide 1
multiple interactions
ISO
[T-2 Toxin co-treated with CGA protein] results in decreased activity of CYP17A1 protein
CTD
PMID:25962641
NCBI chr 1:255,476,861...255,484,547
Ensembl chr 1:255,476,861...255,482,974
G
Cyp19a1
cytochrome P450, family 19, subfamily a, polypeptide 1
decreases expression multiple interactions
ISO
T-2 Toxin results in decreased expression of CYP19A1 mRNA 1-Methyl-3-isobutylxanthine inhibits the reaction [T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of CYP19A1 mRNA]]; T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of CYP19A1 mRNA]
CTD
PMID:22982764 PMID:30951242
NCBI chr 8:63,449,148...63,476,534
Ensembl chr 8:63,449,148...63,476,917
G
Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
multiple interactions increases expression
ISO
Dactinomycin inhibits the reaction [T-2 Toxin results in increased expression of CYP1A1 mRNA]; Resveratrol inhibits the reaction [T-2 Toxin results in increased expression of CYP1A1 mRNA]; T-2 Toxin promotes the reaction [IL1B protein results in increased expression of CYP1A1 mRNA]; T-2 Toxin promotes the reaction [NRF1 protein binds to CYP1A1 promoter]; T-2 Toxin promotes the reaction [SP1 protein binds to CYP1A1 promoter] T-2 Toxin results in increased expression of CYP1A1 mRNA; T-2 Toxin results in increased expression of CYP1A1 protein
CTD
PMID:21453744 PMID:22982764 PMID:31470059
NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
G
Cytl1
cytokine like 1
decreases expression
ISO
T-2 Toxin results in decreased expression of CYTL1 mRNA
CTD
PMID:31863870
NCBI chr14:77,278,635...77,283,645
Ensembl chr14:77,278,636...77,283,645
G
Dars2
aspartyl-tRNA synthetase 2 (mitochondrial)
decreases expression
EXP
T-2 Toxin results in decreased expression of DARS2 mRNA
CTD
PMID:26141394
NCBI chr13:75,842,078...75,870,319
Ensembl chr13:75,836,565...75,869,904
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Dcps
decapping enzyme, scavenger
increases expression
ISO
T-2 Toxin results in increased expression of DCPS mRNA
CTD
PMID:31863870
NCBI chr 8:33,468,669...33,524,407
Ensembl chr 8:41,724,563...41,782,222
G
Dcx
doublecortin
increases expression
ISO
T-2 Toxin results in increased expression of DCX mRNA
CTD
PMID:26314264
NCBI chr X:112,227,455...112,370,291
Ensembl chr X:112,227,455...112,304,161
G
Dcxr
dicarbonyl and L-xylulose reductase
increases expression
ISO
T-2 Toxin results in increased expression of DCXR mRNA
CTD
PMID:31863870
NCBI chr10:106,504,730...106,506,619
G
Ddb2
damage specific DNA binding protein 2
increases expression
ISO
T-2 Toxin results in increased expression of DDB2 mRNA
CTD
PMID:31863870
NCBI chr 3:97,640,923...97,667,617
Ensembl chr 3:97,640,579...97,664,066
G
Ddit3
DNA-damage inducible transcript 3
increases expression multiple interactions
EXP ISO
T-2 Toxin results in increased expression of DDIT3 mRNA; T-2 Toxin results in increased expression of DDIT3 protein salubrinal inhibits the reaction [T-2 Toxin results in increased expression of DDIT3 mRNA]; salubrinal inhibits the reaction [T-2 Toxin results in increased expression of DDIT3 protein] Selenomethionine inhibits the reaction [T-2 Toxin results in increased expression of DDIT3 mRNA]; Selenomethionine inhibits the reaction [T-2 Toxin results in increased expression of DDIT3 protein]
CTD
PMID:26141394 PMID:29454614 PMID:34673134
NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509
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Ddit4
DNA-damage-inducible transcript 4
decreases expression
ISO
T-2 Toxin results in decreased expression of DDIT4 mRNA
CTD
PMID:34581912
NCBI chr20:28,434,938...28,437,037
Ensembl chr20:28,434,944...28,437,037
G
Ddx52
DExD-box helicase 52
increases expression
ISO
T-2 Toxin results in increased expression of DDX52 mRNA
CTD
PMID:31863870
NCBI chr10:69,322,062...69,344,856
Ensembl chr10:69,322,114...69,428,714
G
Ddx55
DEAD-box helicase 55
multiple interactions increases expression
EXP
GABPA promotes the reaction [T-2 Toxin results in increased expression of DDX55 mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to DDX55]
CTD
PMID:36863559
NCBI chr12:32,034,462...32,050,218
Ensembl chr12:37,695,444...37,711,198
G
Ddx56
DEAD-box helicase 56
increases expression
ISO
T-2 Toxin results in increased expression of DDX56 mRNA
CTD
PMID:34581912
NCBI chr14:85,325,942...85,336,262
Ensembl chr14:85,325,942...85,336,262
G
Dffa
DNA fragmentation factor subunit alpha
increases expression
ISO
T-2 Toxin results in increased expression of DFFA mRNA
CTD
PMID:34581912
NCBI chr 5:164,823,807...164,836,729
Ensembl chr 5:164,823,807...164,836,728
G
Dgcr8
DGCR8 microprocessor complex subunit
increases expression
ISO
T-2 Toxin results in increased expression of DGCR8 mRNA
CTD
PMID:34581912
NCBI chr11:82,704,673...82,737,251
Ensembl chr11:96,209,038...96,241,551
G
Dhcr24
24-dehydrocholesterol reductase
decreases expression
ISO
T-2 Toxin results in decreased expression of DHCR24 mRNA
CTD
PMID:31863870 PMID:34581912
NCBI chr 5:126,573,366...126,599,940
Ensembl chr 5:126,573,338...126,599,936
G
Diablo
diablo, IAP-binding mitochondrial protein
increases expression
ISO
T-2 Toxin results in increased expression of DIABLO protein
CTD
PMID:34581912
NCBI chr12:38,716,668...38,731,285
Ensembl chr12:38,716,668...38,731,265
G
Disc1
DISC1 scaffold protein
multiple interactions
EXP
T-2 Toxin promotes the reaction [GABPA protein binds to DISC1]
CTD
PMID:36863559
NCBI chr19:69,911,548...70,120,970
Ensembl chr19:69,911,976...70,120,970
G
Dnajc10
DnaJ heat shock protein family (Hsp40) member C10
decreases expression
ISO
T-2 Toxin results in decreased expression of DNAJC10 mRNA
CTD
PMID:31863870
NCBI chr 3:85,636,890...85,679,620
Ensembl chr 3:85,639,589...85,689,368
G
Dnajc4
DnaJ heat shock protein family (Hsp40) member C4
affects expression
EXP
T-2 Toxin affects the expression of DNAJC4 protein
CTD
PMID:26141394
NCBI chr 1:213,607,397...213,611,614
Ensembl chr 1:213,607,399...213,611,729
G
Dnase1l1
deoxyribonuclease 1-like 1
decreases expression
ISO
T-2 Toxin results in decreased expression of DNASE1L1 mRNA
CTD
PMID:31863870
NCBI chr X:157,208,230...157,216,812
Ensembl chr X:157,208,230...157,216,711
G
Dnase2
deoxyribonuclease 2, lysosomal
decreases expression
ISO
T-2 Toxin results in decreased expression of DNASE2 mRNA
CTD
PMID:31863870
NCBI chr19:40,149,505...40,152,225
Ensembl chr19:40,149,505...40,152,225
G
Dnm1l
dynamin 1-like
increases expression multiple interactions
EXP
T-2 Toxin results in increased expression of DNM1L mRNA GABPA promotes the reaction [T-2 Toxin results in increased expression of DNM1L mRNA]; PINK1 promotes the reaction [T-2 Toxin results in increased expression of DNM1L mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to DNM1L]
CTD
PMID:36863559
NCBI chr11:98,084,049...98,135,663
Ensembl chr11:98,085,397...98,137,420
G
Dnmt1
DNA methyltransferase 1
increases expression
EXP
T-2 Toxin results in increased expression of DNMT1 mRNA; T-2 Toxin results in increased expression of DNMT1 protein
CTD
PMID:31279042
NCBI chr 8:27,716,797...27,763,405
Ensembl chr 8:27,716,797...27,763,119
G
Dnmt3a
DNA methyltransferase 3 alpha
increases expression
EXP
T-2 Toxin results in increased expression of DNMT3A mRNA; T-2 Toxin results in increased expression of DNMT3A protein
CTD
PMID:31279042
NCBI chr 6:32,507,316...32,621,678
Ensembl chr 6:32,512,070...32,614,970
G
Dok3
docking protein 3
increases expression
EXP
T-2 Toxin results in increased expression of DOK3 mRNA
CTD
PMID:26141394
NCBI chr17:9,114,763...9,121,781
Ensembl chr17:9,114,762...9,120,335
G
Dph1
diphthamide biosynthesis 1
increases expression
EXP
T-2 Toxin results in increased expression of DPH1 mRNA
CTD
PMID:26141394
NCBI chr10:60,028,081...60,039,764
Ensembl chr10:60,527,680...60,535,816
G
Dpy19l1
dpy-19 like C-mannosyltransferase 1
decreases expression
ISO
T-2 Toxin results in decreased expression of DPY19L1 mRNA
CTD
PMID:31863870
NCBI chr 8:22,933,163...23,021,461
Ensembl chr 8:31,209,025...31,297,518
G
Dstn
destrin, actin depolymerizing factor
affects expression
EXP
T-2 Toxin affects the expression of DSTN protein
CTD
PMID:26141394
NCBI chr 3:131,284,647...131,311,361
Ensembl chr 3:151,737,849...151,764,769
G
Dusp1
dual specificity phosphatase 1
decreases expression increases expression
EXP ISO
T-2 Toxin results in decreased expression of DUSP1 mRNA T-2 Toxin results in increased expression of DUSP1 mRNA
CTD
PMID:26141394 PMID:34581912
NCBI chr10:17,184,853...17,187,646
Ensembl chr10:17,184,823...17,187,644
G
Dynll1
dynein light chain LC8-type 1
increases expression
ISO
T-2 Toxin results in increased expression of DYNLL1 mRNA
CTD
PMID:34581912
NCBI chr12:46,945,291...46,976,867
Ensembl chr12:46,973,050...46,976,861
G
Ecm2
extracellular matrix protein 2
decreases expression
ISO
T-2 Toxin results in decreased expression of ECM2 mRNA
CTD
PMID:31863870
NCBI chr17:15,326,359...15,358,938
Ensembl chr17:15,326,359...15,358,855
G
Eef1d
eukaryotic translation elongation factor 1 delta
affects expression
EXP
T-2 Toxin affects the expression of EEF1D protein
CTD
PMID:26141394
NCBI chr 7:109,462,645...109,478,021
Ensembl chr 7:109,462,646...109,489,531
G
Eef1g
eukaryotic translation elongation factor 1 gamma
affects expression
EXP
T-2 Toxin affects the expression of EEF1G protein
CTD
PMID:26141394
NCBI chr 1:215,289,815...215,300,421
Ensembl chr 1:215,277,860...215,301,479
G
Eef2
eukaryotic translation elongation factor 2
affects expression
EXP
T-2 Toxin affects the expression of EEF2 protein
CTD
PMID:26141394
NCBI chr 7:9,183,836...9,196,255
Ensembl chr 7:9,183,961...9,189,544
G
Eeig1
estrogen-induced osteoclastogenesis regulator 1
decreases expression
ISO
T-2 Toxin results in decreased expression of EEIG1 mRNA
CTD
PMID:31863870
NCBI chr 3:36,220,170...36,252,377
Ensembl chr 3:36,211,730...36,252,378
G
Efhd1
EF-hand domain family, member D1
decreases expression
ISO
T-2 Toxin results in decreased expression of EFHD1 mRNA
CTD
PMID:31863870
NCBI chr 9:95,386,155...95,432,800
Ensembl chr 9:95,386,169...95,432,798
G
Egf
epidermal growth factor
decreases expression
ISO
T-2 Toxin results in decreased expression of EGF mRNA
CTD
PMID:34581912
NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:220,893,660...220,976,297
G
Eif2ak2
eukaryotic translation initiation factor 2-alpha kinase 2
increases expression
EXP
T-2 Toxin results in increased expression of EIF2AK2 mRNA
CTD
PMID:26141394
NCBI chr 6:21,941,147...21,977,115
Ensembl chr 6:21,952,631...21,977,116
G
Eif2ak3
eukaryotic translation initiation factor 2 alpha kinase 3
decreases expression increases phosphorylation
ISO
T-2 Toxin results in decreased expression of EIF2AK3 mRNA T-2 Toxin results in increased phosphorylation of EIF2AK3 protein
CTD
PMID:31863870 PMID:34673134
NCBI chr 4:104,363,838...104,425,271
Ensembl chr 4:104,363,833...104,425,268
G
Eif2s1
eukaryotic translation initiation factor 2 subunit alpha
increases phosphorylation multiple interactions
EXP ISO
T-2 Toxin results in increased phosphorylation of EIF2S1 protein salubrinal promotes the reaction [T-2 Toxin results in increased phosphorylation of EIF2S1 protein] Selenomethionine inhibits the reaction [T-2 Toxin results in increased phosphorylation of EIF2S1 protein]
CTD
PMID:29454614 PMID:34673134
NCBI chr 6:103,405,880...103,430,549
Ensembl chr 6:103,405,788...103,431,649
G
Eif3d
eukaryotic translation initiation factor 3, subunit D
increases expression
EXP
T-2 Toxin results in increased expression of EIF3D mRNA
CTD
PMID:26141394
NCBI chr 7:111,420,351...111,432,761
Ensembl chr 7:111,420,351...111,432,740
G
Eif3g
eukaryotic translation initiation factor 3, subunit G
increases expression
EXP
T-2 Toxin results in increased expression of EIF3G mRNA
CTD
PMID:26141394
NCBI chr 8:19,429,728...19,433,760
Ensembl chr 8:27,705,915...27,709,987
G
Eif3i
eukaryotic translation initiation factor 3, subunit I
affects expression
EXP
T-2 Toxin affects the expression of EIF3I protein
CTD
PMID:26141394
NCBI chr 5:147,219,457...147,226,910
Ensembl chr 5:147,219,366...147,241,232
G
Eif3j
eukaryotic translation initiation factor 3, subunit J
increases expression
EXP
T-2 Toxin results in increased expression of EIF3J mRNA
CTD
PMID:26141394
NCBI chr 3:129,438,715...129,460,953
Ensembl chr 3:129,438,722...129,462,246
G
Eif4a2
eukaryotic translation initiation factor 4A2
increases expression
EXP
T-2 Toxin results in increased expression of EIF4A2 mRNA
CTD
PMID:26141394
NCBI chr11:91,268,730...91,276,738
Ensembl chr11:91,268,731...91,275,323
G
Eif5a
eukaryotic translation initiation factor 5A
affects expression
EXP
T-2 Toxin affects the expression of EIF5A protein
CTD
PMID:26141394
NCBI chr10:55,138,821...55,143,272
Ensembl chr10:55,138,823...55,143,330
G
Eif6
eukaryotic translation initiation factor 6
affects expression
EXP
T-2 Toxin affects the expression of EIF6 protein
CTD
PMID:26141394
NCBI chr 3:164,785,162...164,791,410
Ensembl chr 3:164,785,163...164,791,525
G
Eloc
elongin C
affects expression
EXP
T-2 Toxin affects the expression of ELOC protein
CTD
PMID:26141394
NCBI chr 5:7,444,769...7,461,187
Ensembl chr 5:7,445,018...7,464,128 Ensembl chr20:7,445,018...7,464,128
G
Emg1
EMG1 N1-specific pseudouridine methyltransferase
increases expression
ISO
T-2 Toxin results in increased expression of EMG1 mRNA
CTD
PMID:34581912
NCBI chr 4:159,195,545...159,203,826
Ensembl chr 4:159,195,564...159,203,826
G
Eno1
enolase 1
affects expression
EXP
T-2 Toxin affects the expression of ENO1 protein
CTD
PMID:26141394
NCBI chr 5:166,002,867...166,014,252
Ensembl chr 3:77,946,261...77,986,003 Ensembl chr 5:77,946,261...77,986,003
G
Eomes
eomesodermin
increases expression
ISO
T-2 Toxin results in increased expression of EOMES mRNA
CTD
PMID:26314264
NCBI chr 8:127,059,215...127,067,070
Ensembl chr 8:127,059,215...127,067,070
G
Epas1
endothelial PAS domain protein 1
multiple interactions increases expression
ISO
BAY 11-7085 inhibits the reaction [T-2 Toxin results in increased expression of EPAS1 mRNA]; BAY 11-7085 inhibits the reaction [T-2 Toxin results in increased expression of EPAS1 protein] T-2 Toxin results in increased expression of EPAS1 mRNA; T-2 Toxin results in increased expression of EPAS1 protein
CTD
PMID:22800716 PMID:34581912
NCBI chr 6:13,543,252...13,626,147
Ensembl chr 6:13,544,389...13,624,729
G
Epb41l2
erythrocyte membrane protein band 4.1-like 2
decreases expression
ISO
T-2 Toxin results in decreased expression of EPB41L2 mRNA
CTD
PMID:34581912
NCBI chr 1:21,682,336...21,857,106
Ensembl chr 1:21,682,335...21,857,105
G
Epb42
erythrocyte membrane protein band 4.2
increases expression
ISO
T-2 Toxin results in increased expression of EPB42 mRNA
CTD
PMID:34581912
NCBI chr 3:107,979,709...107,997,932
Ensembl chr 3:128,433,464...128,451,683
G
Eprs1
glutamyl-prolyl-tRNA synthetase 1
decreases expression
ISO
T-2 Toxin results in decreased expression of EPRS1 mRNA
CTD
PMID:34581912
NCBI chr13:99,431,955...99,503,510
Ensembl chr13:99,433,130...99,503,509
G
Epyc
epiphycan
decreases expression
ISO
T-2 Toxin results in decreased expression of EPYC mRNA
CTD
PMID:31863870
NCBI chr 7:32,436,620...32,474,326
Ensembl chr 7:34,323,273...34,361,032
G
Ereg
epiregulin
multiple interactions
ISO
T-2 Toxin inhibits the reaction [[CGA protein co-treated with FSHB protein] results in increased expression of EREG mRNA]
CTD
PMID:30951242
NCBI chr14:17,311,485...17,325,260
Ensembl chr14:17,311,485...17,325,260
G
Ergic2
ERGIC and golgi 2
decreases expression
EXP
T-2 Toxin results in decreased expression of ERGIC2 mRNA
CTD
PMID:26141394
NCBI chr 4:181,090,808...181,123,074
Ensembl chr 4:182,822,225...182,854,490
G
Ermp1
endoplasmic reticulum metallopeptidase 1
decreases expression
EXP
T-2 Toxin results in decreased expression of ERMP1 mRNA
CTD
PMID:26141394
NCBI chr 1:236,801,459...236,835,656
Ensembl chr 1:236,801,466...236,839,197
G
Ern1
endoplasmic reticulum to nucleus signaling 1
increases expression multiple interactions
ISO
T-2 Toxin results in increased expression of ERN1 protein ERN1 protein promotes the reaction [T-2 Toxin results in decreased expression of ERN2 protein]; ERN1 protein promotes the reaction [T-2 Toxin results in decreased expression of MUC2 protein]
CTD
PMID:31170431
NCBI chr10:91,826,663...91,920,976
Ensembl chr10:91,830,428...91,920,791
G
Ern2
endoplasmic reticulum to nucleus signaling 2
decreases expression multiple interactions
ISO
T-2 Toxin results in decreased expression of ERN2 protein ERN1 protein promotes the reaction [T-2 Toxin results in decreased expression of ERN2 protein]; ERN2 protein inhibits the reaction [T-2 Toxin results in decreased expression of MUC2 protein]
CTD
PMID:31170431
NCBI chr 1:176,726,454...176,743,289
Ensembl chr 1:186,157,691...186,174,521
G
Ero1a
endoplasmic reticulum oxidoreductase 1 alpha
decreases expression
EXP
T-2 Toxin results in decreased expression of ERO1A mRNA
CTD
PMID:26141394
NCBI chr15:20,974,771...21,010,170
Ensembl chr15:20,972,679...21,018,039
G
Erp29
endoplasmic reticulum protein 29
affects expression
EXP
T-2 Toxin affects the expression of ERP29 protein
CTD
PMID:26141394
NCBI chr12:40,750,177...40,756,607
Ensembl chr12:40,750,314...40,757,010
G
Esrra
estrogen related receptor, alpha
affects expression
EXP
T-2 Toxin affects the expression of ESRRA mRNA
CTD
PMID:29870751
NCBI chr 1:213,533,309...213,543,432
Ensembl chr 1:213,533,310...213,543,811
G
Exosc2
exosome component 2
increases expression
ISO
T-2 Toxin results in increased expression of EXOSC2 mRNA
CTD
PMID:34581912
NCBI chr 3:35,360,652...35,370,948
Ensembl chr 3:35,360,666...35,371,373
G
Ezr
ezrin
affects expression
EXP
T-2 Toxin affects the expression of EZR protein
CTD
PMID:26141394
NCBI chr 1:49,373,033...49,416,573
Ensembl chr 1:49,373,035...49,416,573
G
Fam162a
family with sequence similarity 162, member A
increases expression
ISO
T-2 Toxin results in increased expression of FAM162A mRNA
CTD
PMID:31863870
NCBI chr11:78,186,260...78,215,186
Ensembl chr11:78,185,852...78,216,560
G
Fam216a
family with sequence similarity 216, member A
increases expression
ISO
T-2 Toxin results in increased expression of FAM216A mRNA
CTD
PMID:31863870
NCBI chr12:34,198,526...34,207,673
Ensembl chr12:39,859,172...39,868,442
G
Fanci
FA complementation group I
increases expression
EXP
T-2 Toxin results in increased expression of FANCI mRNA
CTD
PMID:26141394
NCBI chr 1:142,736,636...142,792,999
Ensembl chr 1:142,736,653...142,792,999
G
Fbxo2
F-box protein 2
affects expression
EXP
T-2 Toxin affects the expression of FBXO2 protein
CTD
PMID:26141394
NCBI chr 5:163,876,079...163,881,508
Ensembl chr 5:163,875,757...163,881,508
G
Fbxo22
F-box protein 22
increases expression
ISO
T-2 Toxin results in increased expression of FBXO22 mRNA
CTD
PMID:31863870
NCBI chr 8:64,476,034...64,492,063
Ensembl chr 8:64,475,957...64,492,062
G
Fbxo31
F-box protein 31
multiple interactions
EXP
T-2 Toxin promotes the reaction [GABPA protein binds to FBXO31]
CTD
PMID:36863559
NCBI chr19:66,533,437...66,564,674
Ensembl chr19:66,533,437...66,564,674
G
Fbxw4
F-box and WD repeat domain containing 4
increases expression
EXP
T-2 Toxin results in increased expression of FBXW4 mRNA
CTD
PMID:26141394
NCBI chr 1:244,426,892...244,514,188
Ensembl chr 1:254,375,923...254,463,277
G
Fcgr2b
Fc gamma receptor 2B
increases expression
EXP
T-2 Toxin results in increased expression of FCGR2B mRNA
CTD
PMID:26141394
NCBI chr13:85,725,897...85,740,517
Ensembl chr13:85,725,897...85,740,517
G
Fech
ferrochelatase
increases expression
ISO
T-2 Toxin results in increased expression of FECH mRNA
CTD
PMID:34581912
NCBI chr18:60,215,325...60,248,525
Ensembl chr18:60,215,325...60,249,546
G
Fgf4
fibroblast growth factor 4
decreases expression
EXP
T-2 Toxin results in decreased expression of FGF4 mRNA
CTD
PMID:26141394
NCBI chr 1:200,023,937...200,027,793
Ensembl chr 1:209,453,229...209,457,085
G
Fis1
fission, mitochondrial 1
multiple interactions
EXP
PINK1 promotes the reaction [T-2 Toxin results in increased expression of FIS1 mRNA]
CTD
PMID:36863559
NCBI chr12:25,345,239...25,360,135
Ensembl chr12:25,345,239...25,349,335
G
Fkbp4
FKBP prolyl isomerase 4
affects expression
EXP
T-2 Toxin affects the expression of FKBP4 protein
CTD
PMID:26141394
NCBI chr 4:163,389,464...163,397,918
Ensembl chr 4:163,389,464...163,397,918
G
Fmod
fibromodulin
decreases expression
ISO
T-2 Toxin results in decreased expression of FMOD mRNA
CTD
PMID:31863870
NCBI chr13:48,045,567...48,056,184
Ensembl chr13:47,990,774...48,056,183
G
Fosl2
FOS like 2, AP-1 transcription factor subunit
increases expression
ISO
T-2 Toxin results in increased expression of FOSL2 mRNA
CTD
PMID:34581912
NCBI chr 6:30,017,952...30,039,269
Ensembl chr 6:30,021,916...30,039,406
G
Fscn1
fascin actin-bundling protein 1
affects expression
EXP
T-2 Toxin affects the expression of FSCN1 protein
CTD
PMID:26141394
NCBI chr12:16,710,601...16,723,734
Ensembl chr12:16,710,601...16,723,734
G
Fshb
follicle stimulating hormone subunit beta
decreases expression multiple interactions
EXP ISO
T-2 Toxin results in decreased expression of FSHB protein 1-Methyl-3-isobutylxanthine inhibits the reaction [T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of CYP19A1 mRNA]]; 1-Methyl-3-isobutylxanthine inhibits the reaction [T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of LHCGR mRNA]]; 1-Methyl-3-isobutylxanthine inhibits the reaction [T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of STAR mRNA]]; T-2 Toxin inhibits the reaction [[CGA protein co-treated with FSHB protein] results in increased expression of AREG mRNA]; T-2 Toxin inhibits the reaction [[CGA protein co-treated with FSHB protein] results in increased expression of EREG mRNA]; T-2 Toxin inhibits the reaction [[CGA protein co-treated with FSHB protein] results in increased expression of PGR mRNA]; T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of CYP19A1 mRNA]; T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of LHCGR mRNA]; T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of STAR mRNA]; T-2 Toxin inhibits the reaction [FSHB protein results in increased secretion of Estradiol]; T-2 Toxin inhibits the reaction [FSHB protein results in increased secretion of Progesterone]
CTD
PMID:26569305 PMID:30951242
NCBI chr 3:114,003,262...114,007,072
Ensembl chr 3:114,003,262...114,007,072
G
Fubp1
far upstream element binding protein 1
affects expression
EXP
T-2 Toxin affects the expression of FUBP1 protein
CTD
PMID:26141394
NCBI chr 2:243,819,529...243,846,544
Ensembl chr 2:243,819,218...243,846,428
G
Fuca1
alpha-L-fucosidase 1
decreases expression
ISO
T-2 Toxin results in decreased expression of FUCA1 mRNA
CTD
PMID:31863870
NCBI chr 5:153,436,262...153,453,512
Ensembl chr 5:153,436,248...153,453,511
G
G6pd
glucose-6-phosphate dehydrogenase
affects expression decreases expression
EXP
T-2 Toxin affects the expression of G6PD protein T-2 Toxin results in decreased expression of G6PD mRNA
CTD
PMID:26141394
NCBI chr X:157,352,364...157,372,144
Ensembl chr X:157,352,373...157,372,144
G
Gabbr1
gamma-aminobutyric acid type B receptor subunit 1
increases expression decreases expression
EXP ISO
T-2 Toxin results in increased expression of GABBR1 mRNA T-2 Toxin results in decreased expression of GABBR1 mRNA
CTD
PMID:26141394 PMID:34581912
NCBI chr20:1,469,779...1,499,352
Ensembl chr20:1,469,779...1,498,607
G
Gabpa
GA binding protein transcription factor subunit alpha
increases expression multiple interactions
EXP
T-2 Toxin results in increased expression of GABPA mRNA GABPA promotes the reaction [T-2 Toxin results in increased expression of COA5 mRNA]; GABPA promotes the reaction [T-2 Toxin results in increased expression of DDX55 mRNA]; GABPA promotes the reaction [T-2 Toxin results in increased expression of DNM1L mRNA]; GABPA promotes the reaction [T-2 Toxin results in increased expression of NDUFAF1 mRNA]; GABPA promotes the reaction [T-2 Toxin results in increased expression of NDUFAF2 mRNA]; GABPA promotes the reaction [T-2 Toxin results in increased expression of NDUFAF4 mRNA]; GABPA promotes the reaction [T-2 Toxin results in increased expression of NDUFS3 mRNA]; GABPA promotes the reaction [T-2 Toxin results in increased expression of NDUFS7 mRNA]; GABPA promotes the reaction [T-2 Toxin results in increased expression of PEX5 mRNA]; GABPA promotes the reaction [T-2 Toxin results in increased expression of TFAM mRNA]; GABPA promotes the reaction [T-2 Toxin results in increased expression of TFB1M mRNA]; GABPA promotes the reaction [T-2 Toxin results in increased expression of TFB2M mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to AFG1L]; T-2 Toxin promotes the reaction [GABPA protein binds to AR]; T-2 Toxin promotes the reaction [GABPA protein binds to COA5]; T-2 Toxin promotes the reaction [GABPA protein binds to DDX55]; T-2 Toxin promotes the reaction [GABPA protein binds to DISC1]; T-2 Toxin promotes the reaction [GABPA protein binds to DNM1L]; T-2 Toxin promotes the reaction [GABPA protein binds to FBXO31]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFA12]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFA1]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFA4]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFA9]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFAF1]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFAF2]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFAF4]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFB2]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFB3]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFB4]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFB5]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFB7]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFS3]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFS7]; T-2 Toxin promotes the reaction [GABPA protein binds to NSFL1C]; T-2 Toxin promotes the reaction [GABPA protein binds to PARG]; T-2 Toxin promotes the reaction [GABPA protein binds to PEX5]; T-2 Toxin promotes the reaction [GABPA protein binds to TFAM]; T-2 Toxin promotes the reaction [GABPA protein binds to TFB1M]; T-2 Toxin promotes the reaction [GABPA protein binds to TFB2M]; T-2 Toxin promotes the reaction [GABPA protein binds to UQCRFS1]; T-2 Toxin promotes the reaction [GABPA protein binds to YARS2]; T-2 Toxin results in increased expression of and results in increased localization of GABPA protein
CTD
PMID:29870751 PMID:36863559
NCBI chr11:37,375,040...37,404,060
Ensembl chr11:37,375,084...37,404,059
G
Gadd45g
growth arrest and DNA-damage-inducible, gamma
increases expression
EXP
T-2 Toxin results in increased expression of GADD45G mRNA
CTD
PMID:26141394
NCBI chr17:13,528,606...13,530,351
Ensembl chr17:13,528,610...13,530,369
G
Gadd45gip1
GADD45G interacting protein 1
increases expression
ISO
T-2 Toxin results in increased expression of GADD45GIP1 mRNA
CTD
PMID:31863870
NCBI chr19:40,225,503...40,228,052
Ensembl chr19:40,225,984...40,228,055
G
Gal
galanin and GMAP prepropeptide
increases expression
ISO
T-2 Toxin results in increased expression of GAL mRNA
CTD
PMID:31863870
NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:210,079,702...210,084,229
G
Galnt1
polypeptide N-acetylgalactosaminyltransferase 1
decreases expression
ISO
T-2 Toxin results in decreased expression of GALNT1 mRNA
CTD
PMID:31863870
NCBI chr18:15,763,697...15,843,598
Ensembl chr18:15,764,277...15,843,588
G
Gan
gigaxonin
increases expression
ISO
T-2 Toxin results in increased expression of GAN mRNA
CTD
PMID:34581912
NCBI chr19:62,116,600...62,173,879
Ensembl chr19:62,116,600...62,163,083
G
Ganab
glucosidase II alpha subunit
decreases expression
ISO
T-2 Toxin results in decreased expression of GANAB protein
CTD
PMID:34581912
NCBI chr 1:215,222,918...215,242,808
Ensembl chr 1:215,222,995...215,243,036
G
Gapdh
glyceraldehyde-3-phosphate dehydrogenase
affects expression decreases expression
EXP
T-2 Toxin affects the expression of GAPDH protein T-2 Toxin results in decreased expression of GAPDH mRNA
CTD
PMID:26141394
NCBI chr 4:159,648,592...159,653,436
Ensembl chr 4:159,648,592...159,653,377
G
Gas6
growth arrest specific 6
decreases expression
ISO
T-2 Toxin results in decreased expression of GAS6 mRNA
CTD
PMID:31863870
NCBI chr16:82,747,676...82,778,090
Ensembl chr16:82,747,345...82,778,088
G
Gask1b
golgi associated kinase 1B
increases expression
ISO
T-2 Toxin results in increased expression of GASK1B mRNA
CTD
PMID:31863870
NCBI chr 2:165,047,689...165,112,479
Ensembl chr 2:167,345,809...167,410,603
G
Gatb
glutamyl-tRNA amidotransferase subunit B
increases expression
ISO
T-2 Toxin results in increased expression of GATB mRNA
CTD
PMID:31863870
NCBI chr 2:170,930,547...171,017,133
Ensembl chr 2:173,228,568...173,314,661
G
Gatm
glycine amidinotransferase
decreases expression
EXP
T-2 Toxin results in decreased expression of GATM mRNA
CTD
PMID:26141394
NCBI chr 3:130,112,508...130,137,664
Ensembl chr 3:130,112,509...130,129,355
G
Gbe1
1,4-alpha-glucan branching enzyme 1
decreases expression
ISO
T-2 Toxin results in decreased expression of GBE mRNA
CTD
PMID:34581912
NCBI chr11:22,181,194...22,446,640
Ensembl chr11:22,181,103...22,446,638
G
Gbp5
guanylate binding protein 5
increases expression
ISO
T-2 Toxin results in increased expression of GBP5 mRNA
CTD
PMID:36775139
NCBI chr 2:233,910,999...233,930,320
Ensembl chr 2:233,902,113...233,930,826
G
Gclc
glutamate-cysteine ligase, catalytic subunit
decreases expression increases expression
ISO
T-2 Toxin results in decreased expression of GCLC mRNA T-2 Toxin results in increased expression of GCLC mRNA
CTD
PMID:20854872 PMID:33508416
NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:87,510,463...87,548,893
G
Gclm
glutamate cysteine ligase, modifier subunit
decreases expression increases expression
ISO
T-2 Toxin results in decreased expression of GCLM mRNA T-2 Toxin results in increased expression of GCLM mRNA
CTD
PMID:20854872 PMID:33508416
NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:213,031,838...213,055,003
G
Gdf15
growth differentiation factor 15
increases expression
ISO
T-2 Toxin results in increased expression of GDF15 mRNA
CTD
PMID:34581912
NCBI chr16:18,838,436...18,842,022
Ensembl chr16:18,838,436...18,842,022
G
Gdf5
growth differentiation factor 5
increases expression
ISO
T-2 Toxin results in increased expression of GDF5 mRNA
CTD
PMID:31863870
NCBI chr 3:164,914,401...164,918,593
Ensembl chr 3:164,914,401...164,918,593
G
Gdpd5
glycerophosphodiester phosphodiesterase domain containing 5
decreases expression
ISO
T-2 Toxin results in decreased expression of GDPD5 mRNA
CTD
PMID:31863870
NCBI chr 1:163,091,844...163,173,559
Ensembl chr 1:163,091,833...163,173,559
G
Gfpt1
glutamine fructose-6-phosphate transaminase 1
decreases expression
ISO
T-2 Toxin results in decreased expression of GFPT1 mRNA
CTD
PMID:31863870
NCBI chr 4:119,496,691...119,546,472
Ensembl chr 4:121,054,045...121,103,799
G
Gh1
growth hormone 1
multiple interactions decreases expression
EXP
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [T-2 Toxin results in decreased expression of GH1 mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [T-2 Toxin results in decreased expression of GH1 mRNA]; AKNA protein affects the reaction [T-2 Toxin results in decreased expression of GH1 mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in decreased expression of GH1 mRNA]; farnesylthiosalicylic acid inhibits the reaction [T-2 Toxin results in decreased expression of GH1 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [T-2 Toxin results in decreased expression of GH1 mRNA]; SB 203580 inhibits the reaction [T-2 Toxin results in decreased expression of GH1 mRNA]; T-2 Toxin results in decreased expression of and results in decreased secretion of GH1 protein
CTD
PMID:26141394 PMID:29079362
NCBI chr10:91,727,883...91,729,860
Ensembl chr10:91,727,884...91,729,859
G
Ghitm
growth hormone inducible transmembrane protein
decreases expression
EXP
T-2 Toxin results in decreased expression of GHITM mRNA
CTD
PMID:26141394
NCBI chr16:12,885,551...12,897,887
Ensembl chr16:12,905,806...12,918,123
G
Ghrh
growth hormone releasing hormone
increases expression
EXP
T-2 Toxin results in increased expression of GHRH mRNA
CTD
PMID:26141394
NCBI chr 3:166,412,763...166,432,519
Ensembl chr 3:166,412,764...166,431,880
G
Gip
gastric inhibitory polypeptide
multiple interactions increases expression
ISO
T-2 Toxin results in increased expression of and results in increased secretion of GIP protein T-2 Toxin results in increased expression of GIP protein
CTD
PMID:28666375 PMID:29689362
NCBI chr10:81,465,070...81,473,216
Ensembl chr10:81,465,062...81,473,216
G
Glmp
glycosylated lysosomal membrane protein
decreases expression
ISO
T-2 Toxin results in decreased expression of GLMP mRNA
CTD
PMID:31863870
NCBI chr 2:173,794,273...173,797,863
Ensembl chr 2:176,091,839...176,097,208
G
Gnrh1
gonadotropin releasing hormone 1
decreases expression increases expression
EXP
T-2 Toxin results in decreased expression of GNRH1 mRNA T-2 Toxin results in increased expression of GNRH1 mRNA
CTD
PMID:26569305 PMID:26847343
NCBI chr15:46,147,878...46,152,086
Ensembl chr15:46,148,301...46,148,977 Ensembl chr15:46,148,301...46,148,977
G
Gnrhr
gonadotropin releasing hormone receptor
increases expression
EXP
T-2 Toxin results in increased expression of GNRHR mRNA
CTD
PMID:26847343
NCBI chr14:22,211,666...22,229,654
G
Gp6
glycoprotein VI
increases expression
ISO
T-2 Toxin results in increased expression of GP6 mRNA
CTD
PMID:34581912
NCBI chr 1:69,429,232...69,492,709
Ensembl chr 1:78,508,468...78,535,374
G
Gpatch4
G patch domain containing 4
increases expression
ISO
T-2 Toxin results in increased expression of GPATCH4 mRNA
CTD
PMID:31863870
NCBI chr 2:175,797,503...175,816,547
Ensembl chr 2:175,807,682...175,817,358
G
Gpc4
glypican 4
decreases expression
ISO
T-2 Toxin results in decreased expression of GPC4 mRNA
CTD
PMID:31863870
NCBI chr X:131,644,711...131,755,349
Ensembl chr X:136,565,591...136,676,057
G
Gpr21
G protein-coupled receptor 21
decreases expression
ISO
T-2 Toxin results in decreased expression of GPR21 mRNA
CTD
PMID:34581912
NCBI chr 3:21,275,289...21,279,008
Ensembl chr 3:41,685,492...41,698,995
G
Gpr52
G protein-coupled receptor 52
decreases expression
ISO
T-2 Toxin results in decreased expression of GPR52 mRNA
CTD
PMID:34581912
NCBI chr13:72,800,265...72,804,989
Ensembl chr13:75,332,901...75,339,351
G
Gpsm2
G-protein signaling modulator 2
decreases expression
ISO
T-2 Toxin results in decreased expression of GPSM2 mRNA
CTD
PMID:34581912
NCBI chr 2:199,015,250...199,063,788
Ensembl chr 2:199,015,250...199,063,056
G
Gpt
glutamic--pyruvic transaminase
increases activity
ISO
T-2 Toxin results in increased activity of GPT protein
CTD
PMID:23929680
NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160
G
Gpx1
glutathione peroxidase 1
increases expression decreases activity decreases expression
EXP ISO
T-2 Toxin results in increased expression of GPX1 mRNA T-2 Toxin results in decreased activity of GPX1 protein T-2 Toxin results in decreased expression of GPX1 mRNA
CTD
PMID:26141394 PMID:27842451 PMID:29870751 PMID:30091165
NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581
G
Gpx2
glutathione peroxidase 2
decreases expression
EXP
T-2 Toxin results in decreased expression of GPX2 mRNA
CTD
PMID:26141394
NCBI chr 6:101,226,745...101,230,033
Ensembl chr 6:101,226,745...101,230,862
G
Grb10
growth factor receptor bound protein 10
increases expression decreases expression
EXP ISO
T-2 Toxin results in increased expression of GRB10 mRNA T-2 Toxin results in decreased expression of GRB10 mRNA
CTD
PMID:26141394 PMID:34581912
NCBI chr14:90,708,653...90,816,399
Ensembl chr14:90,708,653...90,816,387
G
Gria2
glutamate ionotropic receptor AMPA type subunit 2
decreases expression
ISO
T-2 Toxin results in decreased expression of GRIA2 mRNA
CTD
PMID:26314264
NCBI chr 2:168,247,490...168,367,616
Ensembl chr 2:168,247,496...168,367,616
G
Grin2a
glutamate ionotropic receptor NMDA type subunit 2A
increases expression
ISO
T-2 Toxin results in increased expression of GRIN2A mRNA
CTD
PMID:26314264
NCBI chr10:6,136,458...6,560,003
Ensembl chr10:6,138,037...6,551,378
G
Grm4
glutamate metabotropic receptor 4
decreases expression
EXP
T-2 Toxin results in decreased expression of GRM4 mRNA
CTD
PMID:26141394
NCBI chr20:5,486,024...5,574,668
Ensembl chr20:5,482,977...5,574,668
G
Grn
granulin precursor
decreases expression
ISO
T-2 Toxin results in decreased expression of GRN mRNA
CTD
PMID:31863870
NCBI chr10:87,887,834...87,893,938
Ensembl chr10:87,886,122...87,893,936
G
Gsdma
gasdermin A
decreases expression
EXP
T-2 Toxin results in decreased expression of GSDMA mRNA
CTD
PMID:26141394
NCBI chr10:84,110,590...84,135,804
Ensembl chr10:84,123,314...84,135,804
G
Gsk3b
glycogen synthase kinase 3 beta
decreases expression multiple interactions increases expression
EXP ISO
T-2 Toxin results in decreased expression of GSK3B mRNA 3-methyladenine promotes the reaction [T-2 Toxin results in increased expression of GSK3B protein]
CTD
PMID:26141394 PMID:35289972 PMID:36402210
NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249
G
Gsr
glutathione-disulfide reductase
decreases expression multiple interactions affects expression
ISO
T-2 Toxin results in decreased expression of GSR mRNA T-2 Toxin affects the expression of and affects the activity of GSR protein T-2 Toxin affects the expression of GSR mRNA
CTD
PMID:19526462 PMID:23929680
NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394
G
Gss
glutathione synthetase
affects expression increases expression
EXP ISO
T-2 Toxin affects the expression of GSS protein T-2 Toxin results in increased expression of GSS mRNA
CTD
PMID:26141394 PMID:34581912
NCBI chr 3:164,508,005...164,538,343
Ensembl chr 3:164,508,005...164,538,306
G
Gsto2
glutathione S-transferase omega 2
increases expression
EXP
T-2 Toxin results in increased expression of GSTO2 mRNA
CTD
PMID:26141394
NCBI chr 1:246,731,314...246,757,592
Ensembl chr 1:256,673,274...256,695,146
G
Gstp1
glutathione S-transferase pi 1
affects expression
EXP
T-2 Toxin affects the expression of GSTP1 protein
CTD
PMID:26141394
NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705
G
Gstt2
glutathione S-transferase theta 2
increases expression
EXP
T-2 Toxin results in increased expression of GSTT2 mRNA
CTD
PMID:26141394
NCBI chr20:12,819,053...12,822,724
Ensembl chr20:12,818,540...12,822,718
G
H1f10
H1.10 linker histone
increases expression
EXP
T-2 Toxin results in increased expression of H1F10 mRNA
CTD
PMID:26141394
NCBI chr 4:121,997,834...121,998,897
Ensembl chr 4:121,997,831...121,998,966
G
H2ax
H2A.X variant histone
multiple interactions increases activity
ISO
2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [T-2 Toxin results in increased activity of H2AX protein]
CTD
PMID:20150440
NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079
G
H6pd
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
decreases expression
EXP
T-2 Toxin results in decreased expression of H6PD mRNA
CTD
PMID:26141394
NCBI chr 5:165,717,456...165,753,158
Ensembl chr 5:165,721,654...165,753,125
G
Hapln1
hyaluronan and proteoglycan link protein 1
decreases expression
ISO
T-2 Toxin results in decreased expression of HAPLN1 mRNA
CTD
PMID:31863870
NCBI chr 2:22,366,967...22,431,709
Ensembl chr 2:22,366,967...22,429,098
G
Has2
hyaluronan synthase 2
decreases expression increases expression
ISO
T-2 Toxin results in decreased expression of HAS2 mRNA T-2 Toxin results in increased expression of HAS2 mRNA
CTD
PMID:18196609 PMID:31863870
NCBI chr 7:90,002,929...90,028,933
Ensembl chr 7:90,002,929...90,018,535
G
Hbs1l
HBS1-like translational GTPase
increases expression
ISO
T-2 Toxin results in increased expression of HBS1L mRNA
CTD
PMID:31863870
NCBI chr 1:17,912,139...17,989,651
Ensembl chr 1:17,912,070...17,989,646
G
Hbz
hemoglobin subunit zeta
increases expression
ISO
T-2 Toxin results in increased expression of HBZ mRNA
CTD
PMID:34581912
NCBI chr10:15,343,821...15,345,301
Ensembl chr10:15,848,289...15,849,768
G
Hck
HCK proto-oncogene, Src family tyrosine kinase
increases expression
EXP
T-2 Toxin results in increased expression of HCK mRNA
CTD
PMID:26141394
NCBI chr 3:162,031,833...162,074,933
Ensembl chr 3:162,031,817...162,074,935
G
Helq
helicase, POLQ-like
increases expression
EXP
T-2 Toxin results in increased expression of HELQ mRNA
CTD
PMID:26141394
NCBI chr14:9,122,978...9,167,310
Ensembl chr14:9,122,978...9,167,310
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Hexim2
HEXIM P-TEFb complex subunit 2
increases expression
EXP
T-2 Toxin results in increased expression of HEXIM2 mRNA
CTD
PMID:26141394
NCBI chr10:88,572,102...88,584,856
Ensembl chr10:88,578,996...88,584,855
G
Hif1a
hypoxia inducible factor 1 subunit alpha
increases expression
ISO
T-2 Toxin results in increased expression of HIF1A protein
CTD
PMID:36115646
NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323
G
Hipk3
homeodomain interacting protein kinase 3
decreases expression
EXP
T-2 Toxin results in decreased expression of HIPK3 mRNA
CTD
PMID:26141394
NCBI chr 3:90,796,980...90,866,701
Ensembl chr 3:111,251,863...111,322,772
G
Hist1h2bd
histone cluster 1 H2B family member D
increases expression
ISO
T-2 Toxin results in increased expression of H2BC5 mRNA
CTD
PMID:31863870
NCBI chr17:47,488,627...47,489,008
G
Hmga1
high mobility group AT-hook 1
increases expression
ISO
T-2 Toxin results in increased expression of HMGA1 mRNA
CTD
PMID:31863870
NCBI chr20:5,612,902...5,620,596
Ensembl chr20:5,613,471...5,620,593
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Hmgcr
3-hydroxy-3-methylglutaryl-CoA reductase
decreases expression
ISO
T-2 Toxin results in decreased expression of HMGCR mRNA
CTD
PMID:22982764 PMID:34581912
NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:29,720,553...29,754,533
G
Hmox1
heme oxygenase 1
decreases expression increases expression
ISO
T-2 Toxin results in decreased expression of HMOX1 mRNA; T-2 Toxin results in decreased expression of HMOX1 protein T-2 Toxin results in increased expression of HMOX1 mRNA
CTD
PMID:20854872 PMID:29432840 PMID:33508416
NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
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Hnrnpa2b1
heterogeneous nuclear ribonucleoprotein A2/B1
affects expression
EXP
T-2 Toxin affects the expression of HNRNPA2B1 protein
CTD
PMID:26141394
NCBI chr 4:81,867,354...81,875,886
Ensembl chr 4:81,869,661...81,877,572
G
Hnrnpa3
heterogeneous nuclear ribonucleoprotein A3
affects expression
EXP
T-2 Toxin affects the expression of HNRNPA3 protein
CTD
PMID:26141394
NCBI chr 3:80,984,470...80,999,413
Ensembl chr 3:80,985,969...80,996,043
G
Hnrnpab
heterogeneous nuclear ribonucleoprotein A/B
affects expression
EXP
T-2 Toxin affects the expression of HNRNPAB protein
CTD
PMID:26141394
NCBI chr10:36,358,004...36,363,898
Ensembl chr10:36,358,006...36,364,307
G
Hnrnph1
heterogeneous nuclear ribonucleoprotein H1
affects expression
EXP
T-2 Toxin affects the expression of HNRNPH1 protein
CTD
PMID:26141394
NCBI chr10:35,187,412...35,203,909
Ensembl chr10:35,193,890...35,203,906
G
Hnrnpk
heterogeneous nuclear ribonucleoprotein K
affects expression
EXP
T-2 Toxin affects the expression of HNRNPK protein
CTD
PMID:26141394
NCBI chr17:6,269,302...6,280,429
Ensembl chr17:6,268,385...6,280,565
G
Hp
haptoglobin
increases expression
EXP
T-2 Toxin results in increased expression of HP mRNA
CTD
PMID:26141394
NCBI chr19:54,449,151...54,453,701
Ensembl chr19:54,446,217...54,467,518
G
Hsp90aa1
heat shock protein 90 alpha family class A member 1
affects expression
EXP
T-2 Toxin affects the expression of HSP90AA1 protein
CTD
PMID:26141394
NCBI chr 6:135,523,604...135,529,687
Ensembl chr 6:135,523,616...135,528,499
G
Hsp90ab1
heat shock protein 90 alpha family class B member 1
affects expression decreases expression
EXP
T-2 Toxin affects the expression of HSP90AB1 protein T-2 Toxin results in decreased expression of HSP90AB1 mRNA
CTD
PMID:26141394
NCBI chr 9:22,930,249...22,935,929
Ensembl chr 9:22,931,070...22,935,926
G
Hsp90b1
heat shock protein 90 beta family member 1
affects expression
EXP
T-2 Toxin affects the expression of HSP90B1 protein
CTD
PMID:26141394
NCBI chr 7:22,997,962...23,012,293
Ensembl chr 7:22,997,962...23,012,293
G
Hspa4
heat shock protein family A (Hsp70) member 4
affects expression
EXP
T-2 Toxin affects the expression of HSPA4 protein
CTD
PMID:26141394
NCBI chr10:37,908,866...37,951,994
Ensembl chr10:37,908,866...37,949,835
G
Hspa5
heat shock protein family A (Hsp70) member 5
multiple interactions increases expression affects expression
ISO EXP
salubrinal inhibits the reaction [T-2 Toxin results in increased expression of HSPA5 mRNA]; salubrinal inhibits the reaction [T-2 Toxin results in increased expression of HSPA5 protein]; T-2 Toxin results in increased degradation of and results in decreased expression of HSPA5 protein T-2 Toxin results in increased expression of HSPA5 mRNA; T-2 Toxin results in increased expression of HSPA5 protein Selenomethionine inhibits the reaction [T-2 Toxin results in increased expression of HSPA5 mRNA]; Selenomethionine inhibits the reaction [T-2 Toxin results in increased expression of HSPA5 protein] T-2 Toxin affects the expression of HSPA5 protein
CTD
PMID:19336499 PMID:26141394 PMID:29454614 PMID:31170431 PMID:34673134
NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790
G
Hspa8
heat shock protein family A (Hsp70) member 8
affects expression
EXP
T-2 Toxin affects the expression of HSPA8 protein
CTD
PMID:26141394
NCBI chr 8:50,080,514...50,084,376
Ensembl chr 8:50,080,199...50,084,372
G
Hspa9
heat shock protein family A (Hsp70) member 9
affects expression
EXP
T-2 Toxin affects the expression of HSPA9 protein
CTD
PMID:26141394
NCBI chr18:26,810,004...26,832,958
Ensembl chr18:26,804,774...26,828,398
G
Hspb1
heat shock protein family B (small) member 1
multiple interactions increases expression
ISO
T-2 Toxin results in increased expression of and results in decreased phosphorylation of HSPB1 protein T-2 Toxin results in increased expression of HSPB1 mRNA
CTD
PMID:34581912
NCBI chr12:26,430,640...26,432,301
Ensembl chr12:26,430,640...26,432,301
G
Hspd1
heat shock protein family D (Hsp60) member 1
affects expression
EXP
T-2 Toxin affects the expression of HSPD1 protein
CTD
PMID:26141394
NCBI chr 9:64,073,610...64,084,332
Ensembl chr 9:64,073,611...64,084,037
G
Htra4
HtrA serine peptidase 4
decreases expression
EXP
T-2 Toxin results in decreased expression of HTRA4 mRNA
CTD
PMID:26141394
NCBI chr16:67,001,605...67,015,074
Ensembl chr16:73,704,184...73,717,722
G
Hus1
HUS1 checkpoint clamp component
increases expression
EXP
T-2 Toxin results in increased expression of HUS1 mRNA
CTD
PMID:26141394
NCBI chr14:87,902,458...87,917,221
Ensembl chr14:87,902,458...87,917,134
G
Hyi
hydroxypyruvate isomerase
increases expression
ISO
T-2 Toxin results in increased expression of HYI mRNA
CTD
PMID:31863870
NCBI chr 5:137,179,975...137,182,654
Ensembl chr 5:137,179,976...137,182,654
G
Id2
inhibitor of DNA binding 2
increases expression
ISO
T-2 Toxin results in increased expression of ID2 mRNA
CTD
PMID:34581912
NCBI chr 6:47,469,162...47,470,995
Ensembl chr 6:47,457,554...47,472,961
G
Idh1
isocitrate dehydrogenase (NADP(+)) 1
decreases expression
EXP ISO
T-2 Toxin results in decreased expression of IDH1 mRNA
CTD
PMID:26141394 PMID:34581912
NCBI chr 9:74,027,887...74,057,442
Ensembl chr 9:74,027,892...74,049,555
G
Idh3a
isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha
affects expression
EXP
T-2 Toxin affects the expression of IDH3A protein
CTD
PMID:26141394
NCBI chr 8:63,867,882...63,887,223
Ensembl chr 8:63,867,820...63,887,223
G
Idh3b
isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta
increases expression
ISO
T-2 Toxin results in increased expression of IDH3B mRNA
CTD
PMID:31863870
NCBI chr 3:117,481,845...117,486,909
Ensembl chr 3:137,934,697...137,940,107
G
Ier3
immediate early response 3
increases expression
ISO
T-2 Toxin results in increased expression of IER3 mRNA
CTD
PMID:34581912
NCBI chr20:2,933,173...2,934,377
Ensembl chr20:2,933,174...2,934,377
G
Ifitm10
interferon induced transmembrane protein 10
decreases expression
ISO
T-2 Toxin results in decreased expression of IFITM10 mRNA
CTD
PMID:31863870
NCBI chr 1:197,507,501...197,524,180
Ensembl chr 1:206,936,444...206,954,629
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Ifng
interferon gamma
increases expression
ISO
T-2 Toxin results in increased expression of IFNG protein
CTD
PMID:36115646
NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216
G
Ifrd1
interferon-related developmental regulator 1
increases expression
EXP
T-2 Toxin results in increased expression of IFRD1 mRNA
CTD
PMID:26141394
NCBI chr 6:62,996,560...63,044,996
Ensembl chr 6:62,996,562...63,016,131
G
Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
increases expression
EXP
T-2 Toxin results in increased expression of IGF2BP2 mRNA
CTD
PMID:26141394
NCBI chr11:92,378,908...92,478,893
Ensembl chr11:92,378,908...92,478,867
G
Igfbp4
insulin-like growth factor binding protein 4
decreases expression
EXP
T-2 Toxin results in decreased expression of IGFBP4 mRNA
CTD
PMID:26141394
NCBI chr10:84,491,471...84,503,487
Ensembl chr10:84,485,775...84,503,473
G
Igfbpl1
insulin-like growth factor binding protein-like 1
increases expression
EXP
T-2 Toxin results in increased expression of IGFBPL1 mRNA
CTD
PMID:26141394
NCBI chr 5:64,872,056...64,887,461
Ensembl chr 5:64,872,057...64,887,461
G
Igflr1
IGF-like family receptor 1
increases expression
EXP
T-2 Toxin results in increased expression of IGFLR1 mRNA
CTD
PMID:26141394
NCBI chr 1:85,818,428...85,821,032
Ensembl chr 1:94,945,967...94,948,473
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Ikzf3
IKAROS family zinc finger 3
increases expression
ISO
T-2 Toxin results in increased expression of IKZF3 mRNA
CTD
PMID:34581912
NCBI chr10:83,956,850...84,049,861
Ensembl chr10:83,962,030...84,049,861
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Il10
interleukin 10
affects expression decreases expression
ISO
T-2 Toxin affects the expression of IL10 mRNA T-2 Toxin results in decreased expression of IL10 mRNA; T-2 Toxin results in decreased expression of IL10 protein
CTD
PMID:22960706 PMID:31170431
NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580
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Il11
interleukin 11
increases expression decreases methylation multiple interactions
EXP
T-2 Toxin results in increased expression of IL11 mRNA; T-2 Toxin results in increased expression of IL11 protein T-2 Toxin results in decreased methylation of IL11 promoter Decitabine promotes the reaction [T-2 Toxin results in decreased methylation of IL11 promoter]; Decitabine promotes the reaction [T-2 Toxin results in increased expression of IL11 mRNA]
CTD
PMID:29079362 PMID:31279042
NCBI chr 1:78,098,622...78,104,915
Ensembl chr 1:78,096,930...78,104,915
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Il1a
interleukin 1 alpha
increases expression decreases methylation
ISO EXP
T-2 Toxin results in increased expression of IL1A mRNA T-2 Toxin results in decreased methylation of IL1A promoter
CTD
PMID:21112371 PMID:31279042 PMID:36775139
NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013
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Il1b
interleukin 1 beta
multiple interactions increases expression
ISO EXP
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [T-2 Toxin promotes the reaction [IL1B protein results in increased secretion of CXCL8 protein]]; SB 203580 inhibits the reaction [T-2 Toxin promotes the reaction [IL1B protein results in increased secretion of CXCL8 protein]]; Selenium promotes the reaction [T-2 Toxin results in increased expression of IL1B protein]; T-2 Toxin promotes the reaction [IL1B protein results in increased expression of CXCL8 mRNA]; T-2 Toxin promotes the reaction [IL1B protein results in increased expression of CXCL8 protein]; T-2 Toxin promotes the reaction [IL1B protein results in increased expression of CYP1A1 mRNA]; T-2 Toxin promotes the reaction [IL1B protein results in increased secretion of CXCL8 protein] T-2 Toxin results in increased expression of IL1B mRNA; T-2 Toxin results in increased expression of IL1B protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; AKNA protein affects the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; Decitabine promotes the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; SB 203580 inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA] 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; ATG3 protein inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; BTG2 protein affects the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; Minocycline inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; MIR155 mRNA promotes the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; pyrazolanthrone inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; RHEB protein promotes the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; stattic inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]
CTD
PMID:18196609 PMID:21112371 PMID:21453744 PMID:22454431 PMID:22960706 PMID:29079362 PMID:31170431 PMID:31279042 PMID:32240701 PMID:36775139 PMID:39147216 More...
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
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Il2
interleukin 2
affects secretion increases expression
ISO
T-2 Toxin affects the secretion of IL2 protein T-2 Toxin results in increased expression of IL2 mRNA
CTD
PMID:8560498
NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672
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Il20rb
interleukin 20 receptor subunit beta
decreases expression
ISO
T-2 Toxin results in decreased expression of IL20RB mRNA
CTD
PMID:34581912
NCBI chr 8:100,979,085...101,010,829
Ensembl chr 8:109,854,012...109,889,363
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Il22
interleukin 22
increases expression
EXP
T-2 Toxin results in increased expression of IL22 mRNA
CTD
PMID:26141394
NCBI chr 7:55,687,061...55,691,526
Ensembl chr 7:55,686,896...55,692,201
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Il4
interleukin 4
affects secretion decreases expression
ISO
T-2 Toxin affects the secretion of IL4 protein T-2 Toxin results in decreased expression of IL4 mRNA
CTD
PMID:8560498 PMID:22960706
NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549
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Il5
interleukin 5
affects secretion
ISO
T-2 Toxin affects the secretion of IL5 protein
CTD
PMID:8560498
NCBI chr10:38,375,132...38,378,003
Ensembl chr10:38,375,132...38,378,003
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Il6
interleukin 6
multiple interactions decreases methylation affects expression increases expression
ISO EXP
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; ATG3 protein inhibits the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; BTG2 protein affects the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; Minocycline inhibits the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; MIR155 mRNA affects the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; pyrazolanthrone inhibits the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; RHEB protein promotes the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; stattic inhibits the reaction [T-2 Toxin results in increased expression of IL6 mRNA] T-2 Toxin results in decreased methylation of IL6 promoter T-2 Toxin affects the expression of IL6 mRNA T-2 Toxin results in increased expression of IL6 mRNA; T-2 Toxin results in increased expression of IL6 protein AKNA protein affects the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; Decitabine promotes the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; Decitabine promotes the reaction [T-2 Toxin results in increased expression of IL6 protein]
CTD
PMID:21112371 PMID:22454431 PMID:22960706 PMID:29079362 PMID:31170431 PMID:31279042 PMID:32240701 PMID:36775139 PMID:39147216 More...
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
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Imp4
IMP U3 small nucleolar ribonucleoprotein 4
increases expression
ISO
T-2 Toxin results in increased expression of IMP4 mRNA
CTD
PMID:34581912
NCBI chr 9:36,654,127...36,659,265
Ensembl chr 9:44,150,337...44,157,751
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Insig1
insulin induced gene 1
decreases expression
ISO
T-2 Toxin results in decreased expression of INSIG1 mRNA
CTD
PMID:34581912
NCBI chr 4:8,049,339...8,057,812
Ensembl chr 4:8,049,556...8,057,778
G
Irak1
interleukin-1 receptor-associated kinase 1
increases expression
ISO
T-2 Toxin results in increased expression of IRAK1 mRNA
CTD
PMID:34581912
NCBI chr X:156,919,927...156,929,825
Ensembl chr X:156,920,081...156,929,825
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Irak2
interleukin-1 receptor-associated kinase 2
increases expression
ISO
T-2 Toxin results in increased expression of IRAK2 mRNA
CTD
PMID:34581912
NCBI chr 4:148,341,704...148,398,211
Ensembl chr 4:148,341,719...148,398,210
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Islr
immunoglobulin superfamily containing leucine-rich repeat
decreases expression
ISO
T-2 Toxin results in decreased expression of ISLR mRNA
CTD
PMID:31863870
NCBI chr 8:67,467,013...67,469,989
Ensembl chr 8:67,444,536...67,487,493
G
Itga10
integrin subunit alpha 10
decreases expression
ISO
T-2 Toxin results in decreased expression of ITGA10 mRNA
CTD
PMID:31863870
NCBI chr 2:186,871,711...186,891,012
Ensembl chr 2:186,871,711...186,891,012
G
Itga11
integrin subunit alpha 11
decreases expression
ISO
T-2 Toxin results in decreased expression of ITGA11 mRNA
CTD
PMID:31863870
NCBI chr 8:72,041,432...72,150,137
Ensembl chr 8:72,016,652...72,150,137
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Itgam
integrin subunit alpha M
increases expression multiple interactions
ISO
T-2 Toxin results in increased expression of ITGAM protein Minocycline inhibits the reaction [T-2 Toxin results in increased expression of ITGAM protein]
CTD
PMID:36775139 PMID:39147216
NCBI chr 1:192,089,496...192,139,947
Ensembl chr 1:192,089,542...192,139,943
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Itgb1
integrin subunit beta 1
decreases expression
ISO
T-2 Toxin results in decreased expression of ITGB1 mRNA
CTD
PMID:34581912
NCBI chr19:73,602,277...73,650,271
Ensembl chr19:73,602,126...73,650,269
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Itgb5
integrin subunit beta 5
decreases expression
ISO
T-2 Toxin results in decreased expression of ITGB5 mRNA
CTD
PMID:31863870
NCBI chr11:80,333,588...80,449,373
Ensembl chr11:80,333,590...80,449,373
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Itgbl1
integrin subunit beta like 1
decreases expression
ISO
T-2 Toxin results in decreased expression of ITGBL1 mRNA
CTD
PMID:31863870
NCBI chr15:107,186,792...107,448,335
Ensembl chr15:107,186,689...107,451,098
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Jag1
jagged canonical Notch ligand 1
increases expression
ISO
T-2 Toxin results in increased expression of JAG1 mRNA
CTD
PMID:34581912
NCBI chr 3:144,859,453...144,894,883
Ensembl chr 3:144,859,453...144,894,872
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Jag2
jagged canonical Notch ligand 2
increases expression
ISO
T-2 Toxin results in increased expression of JAG2 mRNA
CTD
PMID:34581912
NCBI chr 6:137,804,133...137,826,738
Ensembl chr 6:137,804,133...137,826,738
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Jak1
Janus kinase 1
increases expression
ISO
T-2 Toxin results in increased expression of JAK1 mRNA
CTD
PMID:22454431
NCBI chr 5:120,895,606...121,004,207
Ensembl chr 5:120,896,046...120,996,758
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Jak2
Janus kinase 2
multiple interactions decreases expression increases expression
ISO
alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in increased expression of JAK2 mRNA]; stattic inhibits the reaction [T-2 Toxin results in increased expression of JAK2 mRNA] T-2 Toxin results in decreased expression of JAK2 mRNA
CTD
PMID:22454431 PMID:34581912
NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:236,408,662...236,468,762
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Jam3
junctional adhesion molecule 3
decreases expression
ISO
T-2 Toxin results in decreased expression of JAM3 mRNA
CTD
PMID:31863870
NCBI chr 8:33,767,606...33,828,451
Ensembl chr 8:33,767,607...33,828,623
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Jdp2
Jun dimerization protein 2
decreases expression
ISO
T-2 Toxin results in decreased expression of JDP2 mRNA
CTD
PMID:31863870
NCBI chr 6:105,261,619...105,302,386
Ensembl chr 6:110,992,806...111,033,392
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Jun
Jun proto-oncogene, AP-1 transcription factor subunit
increases expression
EXP ISO
T-2 Toxin results in increased expression of JUN mRNA
CTD
PMID:26141394 PMID:34581912
NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285
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Kcnc3
potassium voltage-gated channel subfamily C member 3
increases expression
ISO
T-2 Toxin results in increased expression of KCNC3 mRNA
CTD
PMID:34581912
NCBI chr 1:95,080,960...95,095,165
Ensembl chr 1:104,217,472...104,231,672
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Kcnma1
potassium calcium-activated channel subfamily M alpha 1
increases expression
ISO
T-2 Toxin results in increased expression of KCNMA1 mRNA
CTD
PMID:31863870
NCBI chr15:351,065...1,057,117
Ensembl chr15:351,659...1,057,117
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Kdelr2
KDEL endoplasmic reticulum protein retention receptor 2
decreases expression
ISO
T-2 Toxin results in decreased expression of KDELR2 mRNA
CTD
PMID:31863870
NCBI chr12:11,138,820...11,157,117
Ensembl chr12:16,252,424...16,270,719
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Kdelr3
KDEL endoplasmic reticulum protein retention receptor 3
decreases expression
ISO
T-2 Toxin results in decreased expression of KDELR3 mRNA
CTD
PMID:31863870
NCBI chr 7:112,959,632...112,969,858
Ensembl chr 7:112,959,718...112,969,858
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Kdm4d
lysine demethylase 4D
increases expression
ISO
T-2 Toxin results in increased expression of KDM4D mRNA
CTD
PMID:34581912
NCBI chr 8:19,561,253...19,586,412
Ensembl chr 8:19,548,676...19,587,331
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Keap1
Kelch-like ECH-associated protein 1
decreases expression
ISO
T-2 Toxin results in decreased expression of KEAP1 mRNA; T-2 Toxin results in decreased expression of KEAP1 protein
CTD
PMID:35842139
NCBI chr 8:28,044,555...28,054,042
Ensembl chr 8:28,044,555...28,054,042
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Kiaa0232
KIAA0232 homolog
decreases expression
ISO
T-2 Toxin results in decreased expression of KIAA0232 mRNA
CTD
PMID:31863870
NCBI chr14:74,094,421...74,159,316
Ensembl chr14:78,319,105...78,384,014
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Kif16b
kinesin family member 16B
decreases expression
EXP
T-2 Toxin results in decreased expression of KIF16B mRNA
CTD
PMID:26141394
NCBI chr 3:150,428,233...150,707,755
Ensembl chr 3:150,366,838...150,707,770
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Kit
KIT proto-oncogene receptor tyrosine kinase
increases expression
ISO
T-2 Toxin results in increased expression of KIT mRNA
CTD
PMID:34581912
NCBI chr14:32,901,615...32,978,895
Ensembl chr14:32,903,033...32,978,812
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Kitlg
KIT ligand
decreases expression
ISO
T-2 Toxin results in decreased expression of KITLG mRNA; T-2 Toxin results in decreased expression of KITLG protein
CTD
PMID:26314264
NCBI chr 7:36,782,621...36,863,796
Ensembl chr 7:36,782,638...36,863,793
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Klf6
KLF transcription factor 6
increases expression
ISO
T-2 Toxin results in increased expression of KLF6 mRNA
CTD
PMID:34581912
NCBI chr17:69,449,483...69,458,478
Ensembl chr17:69,441,493...69,498,601
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Krt1
keratin 1
decreases expression
EXP
T-2 Toxin results in decreased expression of KRT1 mRNA
CTD
PMID:26141394
NCBI chr 7:134,855,311...134,860,537
Ensembl chr 7:134,855,313...134,860,537
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Krt8
keratin 8
affects expression increases expression
EXP ISO
T-2 Toxin affects the expression of KRT8 protein T-2 Toxin results in increased expression of KRT8 mRNA
CTD
PMID:26141394 PMID:34581912
NCBI chr 7:135,002,886...135,010,339
Ensembl chr 7:135,002,894...135,010,403
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Lama5
laminin subunit alpha 5
increases expression
EXP
T-2 Toxin results in increased expression of LAMA5 mRNA
CTD
PMID:26141394
NCBI chr 3:187,647,904...187,695,974
Ensembl chr 3:187,647,904...187,696,173
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Lars1
leucyl-tRNA synthetase 1
decreases expression
EXP
T-2 Toxin results in decreased expression of LARS1 mRNA
CTD
PMID:26141394
NCBI chr18:34,452,567...34,507,030
Ensembl chr18:34,452,561...34,506,938
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Lbh
LBH regulator of WNT signaling pathway
increases expression
ISO
T-2 Toxin results in increased expression of LBH mRNA
CTD
PMID:34581912
NCBI chr 6:28,321,040...28,344,855
Ensembl chr 6:28,321,040...28,370,238
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Lcp2
lymphocyte cytosolic protein 2
decreases expression
ISO
T-2 Toxin results in decreased expression of LCP2 mRNA
CTD
PMID:34581912
NCBI chr10:18,642,600...18,689,562
Ensembl chr10:19,146,554...19,193,744
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Ldha
lactate dehydrogenase A
increases expression
ISO
T-2 Toxin results in increased expression of LDHA protein
CTD
PMID:36115646
NCBI chr 1:106,508,092...106,517,512
Ensembl chr 1:106,502,182...106,517,521
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Lgals1
galectin 1
affects expression
EXP
T-2 Toxin affects the expression of LGALS1 protein
CTD
PMID:26141394
NCBI chr 7:112,365,695...112,368,801
Ensembl chr 7:112,361,850...112,368,800
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Lgr5
leucine rich repeat containing G protein coupled receptor 5
decreases expression
ISO
T-2 Toxin results in decreased expression of LGR5 mRNA
CTD
PMID:31863870
NCBI chr 7:52,973,151...53,107,964
Ensembl chr 7:52,974,332...53,108,163
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Lhb
luteinizing hormone subunit beta
decreases expression increases secretion
EXP
T-2 Toxin results in decreased expression of LHB protein T-2 Toxin results in increased secretion of LHB protein
CTD
PMID:26569305 PMID:26847343
NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:105,037,457...105,038,445
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Lhcgr
luteinizing hormone/choriogonadotropin receptor
multiple interactions
ISO
1-Methyl-3-isobutylxanthine inhibits the reaction [T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of LHCGR mRNA]]; T-2 Toxin inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of LHCGR mRNA]; T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of LHCGR mRNA]
CTD
PMID:30951242
NCBI chr 6:11,415,361...11,480,834
Ensembl chr 6:11,415,415...11,478,061
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Lin28a
lin-28 homolog A
increases expression
ISO
T-2 Toxin results in increased expression of LIN28A mRNA
CTD
PMID:34581912
NCBI chr 5:146,227,119...146,244,122
Ensembl chr 5:151,510,891...151,527,884
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LOC100909998
zinc finger protein 2-like
increases expression
ISO
T-2 Toxin results in increased expression of ZNF2 mRNA
CTD
PMID:34581912
NCBI chr 3:114,793,783...114,818,395
Ensembl chr 3:135,263,010...135,274,567
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Lrpap1
LDL receptor related protein associated protein 1
affects expression decreases expression
EXP ISO
T-2 Toxin affects the expression of LRPAP1 protein T-2 Toxin results in decreased expression of LRPAP1 mRNA
CTD
PMID:26141394 PMID:31863870
NCBI chr14:75,651,371...75,663,380
Ensembl chr14:79,875,708...79,890,034
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Ltbp2
latent transforming growth factor beta binding protein 2
decreases expression
ISO
T-2 Toxin results in decreased expression of LTBP2 mRNA
CTD
PMID:31863870
NCBI chr 6:110,161,029...110,261,586
Ensembl chr 6:110,161,029...110,257,298
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Lyz2
lysozyme 2
increases expression
ISO
T-2 Toxin results in increased expression of LYZ mRNA
CTD
PMID:34581912
NCBI chr 7:54,792,715...54,798,060
Ensembl chr 7:54,792,716...54,798,011
G
Macf1
microtubule-actin crosslinking factor 1
decreases expression
ISO
T-2 Toxin results in decreased expression of MACF1 mRNA
CTD
PMID:34581912
NCBI chr 5:140,908,829...141,234,127
Ensembl chr 5:140,908,837...141,233,890
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Map1b
microtubule-associated protein 1B
decreases expression
ISO
T-2 Toxin results in decreased expression of MAP1B mRNA
CTD
PMID:34581912
NCBI chr 2:32,551,423...32,644,471
Ensembl chr 2:32,551,423...32,657,094
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Map1lc3b
microtubule-associated protein 1 light chain 3 beta
increases expression multiple interactions affects expression
EXP ISO
T-2 Toxin results in increased expression of MAP1LC3B mRNA 3-methyladenine affects the reaction [T-2 Toxin affects the expression of MAP1LC3B protein] T-2 Toxin results in increased expression of and results in increased cleavage of MAP1LC3B protein
CTD
PMID:29413859 PMID:36402210
NCBI chr19:66,571,631...66,582,270
Ensembl chr19:66,574,407...66,584,358 Ensembl chr16:66,574,407...66,584,358
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Mapk1
mitogen activated protein kinase 1
increases phosphorylation
ISO
T-2 Toxin results in increased phosphorylation of MAPK1 protein
CTD
PMID:36775139
NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
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Mapk8
mitogen-activated protein kinase 8
increases phosphorylation
ISO
T-2 Toxin results in increased phosphorylation of MAPK8 protein
CTD
PMID:36775139
NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427
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Mapk8ip1
mitogen-activated protein kinase 8 interacting protein 1
increases expression
ISO
T-2 Toxin results in increased expression of MAPK8IP1 mRNA
CTD
PMID:34581912
NCBI chr 3:78,355,051...78,372,946
Ensembl chr 3:98,810,541...98,828,368
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Mars2
methionyl-tRNA synthetase 2, mitochondrial
decreases expression
EXP
T-2 Toxin results in decreased expression of MARS2 mRNA
CTD
PMID:26141394
NCBI chr 9:56,720,408...56,729,991
Ensembl chr 9:64,215,128...64,338,443
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Marveld2
MARVEL domain containing 2
increases expression
ISO
T-2 Toxin results in increased expression of MARVELD2 mRNA
CTD
PMID:39147216
NCBI chr 2:31,742,652...31,764,150
Ensembl chr 2:33,462,950...33,498,077
G
Mat2a
methionine adenosyltransferase 2A
decreases expression
ISO
T-2 Toxin results in decreased expression of MAT2A mRNA
CTD
PMID:34581912
NCBI chr 4:106,048,043...106,053,612
Ensembl chr 4:106,038,254...106,053,645
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Mbtps1
membrane-bound transcription factor peptidase, site 1
decreases expression
ISO
T-2 Toxin results in decreased expression of MBTPS1 mRNA
CTD
PMID:31863870 PMID:34581912
NCBI chr19:64,470,245...64,521,438
Ensembl chr19:64,470,545...64,521,342
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Mcf2l
MCF.2 cell line derived transforming sequence-like
decreases expression
EXP
T-2 Toxin results in decreased expression of MCF2L mRNA
CTD
PMID:26141394
NCBI chr16:76,507,133...76,652,893
Ensembl chr16:83,209,280...83,354,956
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Mcm7
minichromosome maintenance complex component 7
affects expression
EXP
T-2 Toxin affects the expression of MCM7 protein
CTD
PMID:26141394
NCBI chr12:22,155,921...22,163,320
Ensembl chr12:22,155,921...22,163,771
G
Mdh1
malate dehydrogenase 1
affects expression
EXP
T-2 Toxin affects the expression of MDH1 protein
CTD
PMID:26141394
NCBI chr14:99,831,934...99,847,227
Ensembl chr14:99,831,615...99,847,232
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Mdm2
MDM2 proto-oncogene
increases expression
EXP ISO
T-2 Toxin results in increased expression of MDM2 mRNA
CTD
PMID:26141394 PMID:31863870
NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:55,176,560...55,200,791
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Megf6
multiple EGF-like-domains 6
decreases expression
ISO
T-2 Toxin results in decreased expression of MEGF6 mRNA
CTD
PMID:31863870
NCBI chr 5:164,738,272...164,839,142
Ensembl chr 5:170,020,778...170,121,554
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Meltf
melanotransferrin
decreases expression
ISO
T-2 Toxin results in decreased expression of MELTF mRNA
CTD
PMID:31863870
NCBI chr11:82,389,420...82,411,270
Ensembl chr11:82,389,420...82,411,270
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Mesd
mesoderm development LRP chaperone
affects expression
EXP
T-2 Toxin affects the expression of MESD protein
CTD
PMID:26141394
NCBI chr 1:137,866,707...137,879,999
Ensembl chr 1:147,275,396...147,289,134
G
Metrnl
meteorin-like, glial cell differentiation regulator
decreases expression
ISO
T-2 Toxin results in decreased expression of METRNL mRNA
CTD
PMID:31863870
NCBI chr10:107,462,148...107,476,143
Ensembl chr10:107,462,109...107,476,135
G
Mettl9
methyltransferase 9, His-X-His N1(pi)-histidine
decreases expression
ISO
T-2 Toxin results in decreased expression of METTL9 mRNA
CTD
PMID:31863870
NCBI chr 1:175,575,805...175,623,065
Ensembl chr 1:185,006,954...185,054,861
G
Mfge8
milk fat globule EGF and factor V/VIII domain containing
decreases expression
ISO
T-2 Toxin results in decreased expression of MFGE8 mRNA
CTD
PMID:31863870
NCBI chr 1:133,064,665...133,080,069
Ensembl chr 1:142,474,028...142,489,431
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Mfn1
mitofusin 1
multiple interactions
EXP
PINK1 promotes the reaction [T-2 Toxin results in increased expression of MFN1 mRNA]
CTD
PMID:36863559
NCBI chr 2:117,240,525...117,288,017
Ensembl chr 2:117,241,759...117,290,190
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Mir155
microRNA 155
multiple interactions increases expression
ISO
MIR155 mRNA affects the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; MIR155 mRNA inhibits the reaction [T-2 Toxin results in increased expression of ATG3 mRNA]; MIR155 mRNA inhibits the reaction [T-2 Toxin results in increased expression of ATG3 protein]; MIR155 mRNA inhibits the reaction [T-2 Toxin results in increased expression of RHEB mRNA]; MIR155 mRNA inhibits the reaction [T-2 Toxin results in increased expression of RHEB protein]; MIR155 mRNA inhibits the reaction [T-2 Toxin results in increased expression of SOCS1 mRNA]; MIR155 mRNA promotes the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; MIR155 mRNA promotes the reaction [T-2 Toxin results in increased expression of TNF mRNA] T-2 Toxin results in increased expression of MIR155 mRNA
CTD
PMID:32240701
NCBI chr11:37,261,114...37,261,178
Ensembl chr11:37,261,114...37,261,178
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Mknk2
MAPK interacting serine/threonine kinase 2
decreases expression
ISO
T-2 Toxin results in decreased expression of MKNK2 mRNA
CTD
PMID:31863870
NCBI chr 7:9,690,385...9,701,527
Ensembl chr 7:9,690,421...9,701,529
G
Mlkl
mixed lineage kinase domain like pseudokinase
increases phosphorylation multiple interactions affects response to substance
ISO EXP
T-2 Toxin results in increased phosphorylation of MLKL protein MLKL protein affects the reaction [T-2 Toxin results in decreased expression of COL2A1 protein]; MLKL protein affects the reaction [T-2 Toxin results in increased expression of MLKL protein] MLKL protein affects the susceptibility to T-2 Toxin
CTD
PMID:39966150
NCBI chr19:56,186,860...56,213,886
Ensembl chr19:56,186,860...56,213,858
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Mlph
melanophilin
decreases expression
ISO
T-2 Toxin results in decreased expression of MLPH mRNA
CTD
PMID:39147216
NCBI chr 9:98,955,036...98,990,566
Ensembl chr 9:98,955,141...98,990,556
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Mmd
monocyte to macrophage differentiation-associated
decreases expression
EXP
T-2 Toxin results in decreased expression of MMD mRNA
CTD
PMID:26141394
NCBI chr10:75,073,278...75,101,528
Ensembl chr10:75,570,397...75,598,609
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Mmp1
matrix metallopeptidase 1
increases expression
ISO
T-2 Toxin results in increased expression of MMP1 protein
CTD
PMID:21144892
NCBI chr 8:12,943,453...12,963,966
Ensembl chr 8:12,943,453...12,963,964
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Mmp12
matrix metallopeptidase 12
increases expression
ISO
T-2 Toxin results in increased expression of MMP12 mRNA
CTD
PMID:22800716
NCBI chr 8:12,866,652...12,876,554
Ensembl chr 8:12,866,641...12,884,478
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Mmp13
matrix metallopeptidase 13
multiple interactions increases expression
ISO EXP
4-(4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridin-2-yl)-N-(tetrahydro-2H-pyran-4-yl)benzamide inhibits the reaction [T-2 Toxin results in increased expression of MMP13 mRNA]; 4-(4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridin-2-yl)-N-(tetrahydro-2H-pyran-4-yl)benzamide inhibits the reaction [T-2 Toxin results in increased expression of MMP13 protein]; Selenium inhibits the reaction [T-2 Toxin results in increased expression of MMP13 mRNA]; Selenium inhibits the reaction [T-2 Toxin results in increased expression of MMP13 protein] [salubrinal co-treated with T-2 Toxin] results in increased expression of MMP13 mRNA; salubrinal inhibits the reaction [T-2 Toxin results in increased expression of MMP13 protein] T-2 Toxin results in increased expression of MMP13 mRNA; T-2 Toxin results in increased expression of MMP13 protein
CTD
PMID:21144892 PMID:22800716 PMID:34673134 PMID:35213812 PMID:39966150
NCBI chr 8:12,782,829...12,793,108
Ensembl chr 8:12,782,813...12,793,105
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Mmp2
matrix metallopeptidase 2
increases activity decreases expression
ISO
T-2 Toxin results in increased activity of MMP2 protein T-2 Toxin results in decreased expression of MMP2 mRNA
CTD
PMID:21112371 PMID:22960706
NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856
G
Mmp3
matrix metallopeptidase 3
increases expression
ISO
T-2 Toxin results in increased expression of MMP3 mRNA
CTD
PMID:22800716
NCBI chr 8:12,925,267...12,938,828
Ensembl chr 8:12,925,280...12,938,826
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Mmp9
matrix metallopeptidase 9
affects expression increases expression multiple interactions increases activity
ISO EXP
T-2 Toxin affects the expression of MMP9 mRNA T-2 Toxin results in increased expression of MMP9 mRNA 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [T-2 Toxin results in increased expression of MMP9 mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [T-2 Toxin results in increased expression of MMP9 mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in increased expression of MMP9 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [T-2 Toxin results in increased expression of MMP9 mRNA]; SB 203580 inhibits the reaction [T-2 Toxin results in increased expression of MMP9 mRNA] T-2 Toxin results in increased expression of and results in increased activity of MMP9 protein T-2 Toxin results in increased activity of MMP9 protein
CTD
PMID:21112371 PMID:22800716 PMID:22960706 PMID:29079362
NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442
G
Mpdu1
mannose-P-dolichol utilization defect 1
increases expression
ISO
T-2 Toxin results in increased expression of MPDU1 mRNA
CTD
PMID:31863870
NCBI chr10:54,374,719...54,380,301
Ensembl chr10:54,873,473...54,879,195
G
Mphosph9
M-phase phosphoprotein 9
decreases expression
ISO
T-2 Toxin results in decreased expression of MPHOSPH9 mRNA
CTD
PMID:34581912
NCBI chr12:37,936,442...38,007,053
Ensembl chr12:37,936,885...38,003,348
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Mpo
myeloperoxidase
increases activity
ISO
T-2 Toxin results in increased activity of MPO protein
CTD
PMID:22960706
NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056
G
Mpst
mercaptopyruvate sulfurtransferase
affects expression
EXP
T-2 Toxin affects the expression of MPST protein
CTD
PMID:26141394
NCBI chr 7:111,836,079...111,843,651
Ensembl chr 7:111,835,587...111,843,650
G
Mrap2
melanocortin 2 receptor accessory protein 2
decreases expression
ISO
T-2 Toxin results in decreased expression of MRAP2 mRNA
CTD
PMID:31863870
NCBI chr 8:96,968,239...97,024,581
Ensembl chr 8:96,988,079...97,024,579
G
Mre11
MRE11 homolog, double strand break repair nuclease
decreases expression
ISO
T-2 Toxin results in decreased expression of MRE11A mRNA
CTD
PMID:34581912
NCBI chr 8:19,900,211...19,961,906
Ensembl chr 8:19,913,772...19,961,904
G
Mrpl58
mitochondrial ribosomal protein L58
increases expression
ISO
T-2 Toxin results in increased expression of MRPL58 mRNA
CTD
PMID:31863870
NCBI chr10:101,145,342...101,151,838
Ensembl chr10:101,145,162...101,151,838
G
Mrps18c
mitochondrial ribosomal protein S18C
increases expression
ISO
T-2 Toxin results in increased expression of MRPS18C mRNA
CTD
PMID:31863870
NCBI chr14:9,116,688...9,122,943
G
Mrps22
mitochondrial ribosomal protein S22
increases expression
ISO
T-2 Toxin results in increased expression of MRPS22 mRNA
CTD
PMID:31863870
NCBI chr 8:108,063,468...108,076,638
Ensembl chr 8:108,063,471...108,076,638
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Ms4a3
membrane spanning 4-domains A3
decreases expression
ISO
T-2 Toxin results in decreased expression of MS4A3 mRNA; T-2 Toxin results in decreased expression of MS4A3 protein
CTD
PMID:34581912
NCBI chr 1:208,462,300...208,480,129
Ensembl chr 1:217,887,105...217,904,907
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Msmo1
methylsterol monooxygenase 1
decreases expression
ISO
T-2 Toxin results in decreased expression of MSMO1 mRNA
CTD
PMID:34581912
NCBI chr16:29,747,113...29,764,360
Ensembl chr16:29,747,137...29,764,445
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Mt-atp6
mitochondrially encoded ATP synthase membrane subunit 6
affects expression
EXP
T-2 Toxin affects the expression of ATP6 mRNA
CTD
PMID:29870751
NCBI chr MT:7,919...8,599
Ensembl chr MT:7,904...8,584
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Mt-atp8
mitochondrially encoded ATP synthase membrane subunit 8
increases expression
EXP
T-2 Toxin results in increased expression of ATP8 mRNA
CTD
PMID:29870751
NCBI chr MT:7,758...7,961
Ensembl chr MT:7,743...7,946
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Mt-co1
mitochondrially encoded cytochrome c oxidase I
increases expression
EXP
T-2 Toxin results in increased expression of COX1 mRNA
CTD
PMID:29870751
NCBI chr MT:5,323...6,867
Ensembl chr MT:5,309...6,853
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Mt-co2
mitochondrially encoded cytochrome c oxidase II
increases expression
EXP
T-2 Toxin results in increased expression of COX2 mRNA
CTD
PMID:29870751
NCBI chr MT:7,006...7,689
Ensembl chr MT:6,991...7,674
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Mt-co3
mitochondrially encoded cytochrome c oxidase III
increases expression
EXP
T-2 Toxin results in increased expression of COX3 mRNA
CTD
PMID:29870751
NCBI chr MT:8,599...9,382
Ensembl chr MT:8,584...9,367
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Mt-cyb
mitochondrially encoded cytochrome b
decreases expression
EXP
T-2 Toxin results in decreased expression of CYTB mRNA
CTD
PMID:29870751
NCBI chr MT:14,136...15,278
Ensembl chr MT:14,124...15,266
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Mt-nd3
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3
increases expression
EXP
T-2 Toxin results in increased expression of ND3 mRNA
CTD
PMID:29870751
NCBI chr MT:9,451...9,798
Ensembl chr MT:9,436...9,783
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Mt-nd5
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5
increases expression
EXP
T-2 Toxin results in increased expression of ND5 mRNA
CTD
PMID:29870751
NCBI chr MT:11,736...13,565
Ensembl chr MT:11,721...13,553
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Mt-nd6
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6
increases expression
EXP
T-2 Toxin results in increased expression of ND6 mRNA
CTD
PMID:29870751
NCBI chr MT:13,543...14,061
Ensembl chr MT:13,531...14,049
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Mthfd2
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
decreases expression
EXP ISO
T-2 Toxin results in decreased expression of MTHFD2 mRNA
CTD
PMID:26141394 PMID:31863870
NCBI chr 4:117,368,833...117,380,350
Ensembl chr 4:117,368,835...117,380,350
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Mtor
mechanistic target of rapamycin kinase
affects expression
EXP
T-2 Toxin affects the expression of MTOR protein
CTD
PMID:29413859
NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:164,167,928...164,277,435
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Mtpn
myotrophin
affects expression
EXP
T-2 Toxin affects the expression of MTPN protein
CTD
PMID:26141394
NCBI chr 4:65,126,390...65,153,803
Ensembl chr 4:65,115,980...65,153,924
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Muc2
mucin 2, oligomeric mucus/gel-forming
multiple interactions decreases expression
ISO
ERN1 protein promotes the reaction [T-2 Toxin results in decreased expression of MUC2 protein]; ERN2 protein inhibits the reaction [T-2 Toxin results in decreased expression of MUC2 protein]
CTD
PMID:31170431
NCBI chr 1:206,225,775...206,261,280
Ensembl chr 1:206,229,035...206,261,280
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Myc
MYC proto-oncogene, bHLH transcription factor
decreases expression
ISO
T-2 Toxin results in decreased expression of MYC mRNA
CTD
PMID:35289972
NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028
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Nanos1
nanos C2HC-type zinc finger 1
decreases expression
ISO
T-2 Toxin results in decreased expression of NANOS1 mRNA
CTD
PMID:31863870
NCBI chr 1:269,883,713...269,887,611
Ensembl chr 1:269,883,536...269,895,417
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Nars1
asparaginyl-tRNA synthetase 1
decreases expression
EXP
T-2 Toxin results in decreased expression of NARS1 mRNA
CTD
PMID:26141394
NCBI chr18:60,259,506...60,275,782
Ensembl chr18:60,259,516...60,275,782
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Ndufa1
NADH:ubiquinone oxidoreductase subunit A1
multiple interactions
EXP
T-2 Toxin promotes the reaction [GABPA protein binds to NDUFA1]
CTD
PMID:36863559
NCBI chr X:121,289,904...121,293,555
Ensembl chr X:121,289,925...121,293,555
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Ndufa12
NADH:ubiquinone oxidoreductase subunit A12
multiple interactions
EXP
T-2 Toxin promotes the reaction [GABPA protein binds to NDUFA12]
CTD
PMID:36863559
NCBI chr 7:30,658,316...30,685,302
Ensembl chr 7:30,658,322...30,686,300
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Ndufa4
Ndufa4, mitochondrial complex associated
multiple interactions
EXP
T-2 Toxin promotes the reaction [GABPA protein binds to NDUFA4]
CTD
PMID:36863559
NCBI chr 4:40,002,216...40,009,384
Ensembl chr 4:40,968,391...40,975,559
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Ndufa9
NADH:ubiquinone oxidoreductase subunit A9
multiple interactions
EXP
T-2 Toxin promotes the reaction [GABPA protein binds to NDUFA9]
CTD
PMID:36863559
NCBI chr 4:161,345,398...161,374,188
Ensembl chr 4:161,345,400...161,375,025
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Ndufaf1
NADH:ubiquinone oxidoreductase complex assembly factor 1
increases expression multiple interactions
EXP
T-2 Toxin results in increased expression of NDUFAF1 mRNA GABPA promotes the reaction [T-2 Toxin results in increased expression of NDUFAF1 mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFAF1]
CTD
PMID:29870751 PMID:36863559
NCBI chr 3:127,089,893...127,104,357
Ensembl chr 3:127,093,659...127,104,020
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Ndufaf2
NADH:ubiquinone oxidoreductase complex assembly factor 2
increases expression multiple interactions
EXP
T-2 Toxin results in increased expression of NDUFAF2 mRNA GABPA promotes the reaction [T-2 Toxin results in increased expression of NDUFAF2 mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFAF2]
CTD
PMID:29870751 PMID:36863559
NCBI chr 2:41,269,141...41,380,895
Ensembl chr 2:41,269,141...41,380,763
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Ndufaf3
NADH:ubiquinone oxidoreductase complex assembly factor 3
increases expression
EXP
T-2 Toxin results in increased expression of NDUFAF3 mRNA
CTD
PMID:29870751
NCBI chr 8:118,139,891...118,141,723
Ensembl chr 8:118,139,892...118,141,723
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Ndufaf4
NADH:ubiquinone oxidoreductase complex assembly factor 4
increases expression multiple interactions
EXP
T-2 Toxin results in increased expression of NDUFAF4 mRNA GABPA promotes the reaction [T-2 Toxin results in increased expression of NDUFAF4 mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFAF4]
CTD
PMID:29870751 PMID:36863559
NCBI chr 5:43,401,795...43,406,967
G
Ndufb2
NADH:ubiquinone oxidoreductase subunit B2
multiple interactions
EXP
T-2 Toxin promotes the reaction [GABPA protein binds to NDUFB2]
CTD
PMID:36863559
NCBI chr 4:69,334,307...69,341,394
Ensembl chr 4:69,334,307...69,340,136 Ensembl chr15:69,334,307...69,340,136
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Ndufb3
NADH:ubiquinone oxidoreductase subunit B3
multiple interactions
EXP
T-2 Toxin promotes the reaction [GABPA protein binds to NDUFB3]
CTD
PMID:36863559
NCBI chr 9:60,129,240...60,139,452
Ensembl chr 9:67,623,614...67,633,613
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Ndufb4
NADH:ubiquinone oxidoreductase subunit B4
multiple interactions
EXP
T-2 Toxin promotes the reaction [GABPA protein binds to NDUFB4]
CTD
PMID:36863559
NCBI chr11:63,063,723...63,070,426
Ensembl chr11:76,569,178...76,575,879
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Ndufb5
NADH:ubiquinone oxidoreductase subunit B5
multiple interactions
EXP
T-2 Toxin promotes the reaction [GABPA protein binds to NDUFB5]
CTD
PMID:36863559
NCBI chr 2:117,447,605...117,461,943
Ensembl chr 2:117,447,035...117,461,590
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Ndufb7
NADH:ubiquinone oxidoreductase subunit B7
multiple interactions
EXP
T-2 Toxin promotes the reaction [GABPA protein binds to NDUFB7]
CTD
PMID:36863559
NCBI chr19:41,472,953...41,477,291
Ensembl chr19:41,472,953...41,477,291
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Ndufs1
NADH:ubiquinone oxidoreductase core subunit S1
increases expression
EXP
T-2 Toxin results in increased expression of NDUFS1 mRNA
CTD
PMID:29870751
NCBI chr 9:72,040,286...72,073,605
Ensembl chr 9:72,040,090...72,073,605
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Ndufs3
NADH:ubiquinone oxidoreductase core subunit S3
affects expression multiple interactions increases expression
EXP
T-2 Toxin affects the expression of NDUFS3 protein GABPA promotes the reaction [T-2 Toxin results in increased expression of NDUFS3 mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFS3]
CTD
PMID:26141394 PMID:29870751 PMID:36863559
NCBI chr 3:97,332,477...97,339,654
Ensembl chr 3:97,332,477...97,345,323
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Ndufs4
NADH:ubiquinone oxidoreductase subunit S4
increases expression
EXP
T-2 Toxin results in increased expression of NDUFS4 mRNA
CTD
PMID:29870751
NCBI chr 2:47,684,420...47,794,914
Ensembl chr 2:47,684,406...47,794,931
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Ndufs5
NADH:ubiquinone oxidoreductase subunit S5
decreases expression
EXP
T-2 Toxin results in decreased expression of NDUFS5 mRNA
CTD
PMID:29870751
NCBI chr 5:141,258,828...141,264,552
Ensembl chr 2:184,849,197...185,028,909 Ensembl chr 5:184,849,197...185,028,909 Ensembl chr14:184,849,197...185,028,909
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Ndufs6
NADH:ubiquinone oxidoreductase subunit S6
increases expression
EXP
T-2 Toxin results in increased expression of NDUFS6 mRNA
CTD
PMID:29870751
NCBI chr 1:31,797,400...31,805,965
Ensembl chr 1:31,797,394...31,805,965
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Ndufs7
NADH:ubiquinone oxidoreductase core subunit S7
increases expression multiple interactions
EXP
T-2 Toxin results in increased expression of NDUFS7 mRNA GABPA promotes the reaction [T-2 Toxin results in increased expression of NDUFS7 mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFS7]
CTD
PMID:29870751 PMID:36863559
NCBI chr 7:10,103,226...10,110,862
Ensembl chr 7:10,103,227...10,110,691
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Ndufs8
NADH:ubiquinone oxidoreductase core subunit S8
increases expression
EXP
T-2 Toxin results in increased expression of NDUFS8 mRNA
CTD
PMID:29870751
NCBI chr 1:201,140,585...201,144,573
Ensembl chr 1:210,569,824...210,572,971
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Ndufv1
NADH:ubiquinone oxidoreductase core subunit V1
increases expression
EXP
T-2 Toxin results in increased expression of NDUFV1 mRNA
CTD
PMID:29870751
NCBI chr 1:201,300,365...201,305,461
Ensembl chr 1:210,729,858...210,734,949
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Ndufv2
NADH:ubiquinone oxidoreductase core subunit V2
increases expression
EXP
T-2 Toxin results in increased expression of NDUFV2 mRNA
CTD
PMID:29870751
NCBI chr 9:113,137,305...113,157,571
Ensembl chr 9:113,137,306...113,157,520
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Ndufv3
NADH:ubiquinone oxidoreductase subunit V3
increases expression
EXP
T-2 Toxin results in increased expression of NDUFV3 mRNA
CTD
PMID:29870751
NCBI chr20:9,613,786...9,622,941
Ensembl chr13:48,468,224...48,488,847 Ensembl chr20:48,468,224...48,488,847
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Nefh
neurofilament heavy chain
increases expression
ISO
T-2 Toxin results in increased expression of NEFH mRNA
CTD
PMID:34581912
NCBI chr14:84,044,428...84,054,413
Ensembl chr14:84,044,023...84,054,417
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Nelfe
negative elongation factor complex member E
increases expression
ISO
T-2 Toxin results in increased expression of NELFE mRNA
CTD
PMID:34581912
NCBI chr20:3,981,259...3,987,016
Ensembl chr20:3,981,261...3,986,922
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Nfe2l2
NFE2 like bZIP transcription factor 2
decreases expression multiple interactions increases expression
ISO EXP
T-2 Toxin results in decreased expression of NFE2L2 mRNA; T-2 Toxin results in decreased expression of NFE2L2 protein NFE2L2 protein affects the reaction [T-2 Toxin results in decreased expression of NRF1 mRNA]; NFE2L2 protein affects the reaction [T-2 Toxin results in decreased expression of NRF1 protein]; NFE2L2 protein affects the reaction [T-2 Toxin results in decreased expression of PPARGC1A mRNA]; NFE2L2 protein affects the reaction [T-2 Toxin results in decreased expression of PPARGC1A protein]; NFE2L2 protein affects the reaction [T-2 Toxin results in decreased expression of TFAM mRNA]; NFE2L2 protein affects the reaction [T-2 Toxin results in decreased expression of TFAM protein] T-2 Toxin results in increased expression of NFE2L2 mRNA; T-2 Toxin results in increased expression of NFE2L2 protein N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [T-2 Toxin results in increased expression of NFE2L2 protein]; NFE2L2 protein affects the reaction [T-2 Toxin results in increased expression of PINK1 protein]
CTD
PMID:20854872 PMID:29432840 PMID:29870751 PMID:33508416 PMID:35842139
NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090
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Nfkbia
NFKB inhibitor alpha
multiple interactions increases phosphorylation
ISO
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [T-2 Toxin results in increased phosphorylation of NFKBIA protein]; BAY 11-7085 inhibits the reaction [T-2 Toxin results in decreased expression of and results in increased degradation of NFKBIA protein]; BTG2 protein affects the reaction [T-2 Toxin results in increased phosphorylation of NFKBIA protein]; T-2 Toxin results in increased degradation of and results in decreased expression of NFKBIA protein
CTD
PMID:22800716 PMID:36775139 PMID:39147216
NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072
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Nfkbil1
NFKB inhibitor like 1
increases expression
EXP
T-2 Toxin results in increased expression of NFKBIL1 mRNA
CTD
PMID:26141394
NCBI chr20:3,595,319...3,610,295
Ensembl chr20:3,595,284...3,610,294
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Nfrkb
nuclear factor related to kappa B binding protein
increases expression
EXP
T-2 Toxin results in increased expression of NFRKB mRNA
CTD
PMID:26141394
NCBI chr 8:38,089,574...38,121,506
Ensembl chr 8:38,089,999...38,121,501
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Nhej1
nonhomologous end-joining factor 1
increases expression
ISO
T-2 Toxin results in increased expression of NHEJ1 mRNA
CTD
PMID:34581912
NCBI chr 9:83,974,995...84,071,161
Ensembl chr 9:83,974,997...84,070,594
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Niban1
niban apoptosis regulator 1
decreases expression
ISO
T-2 Toxin results in decreased expression of NIBAN1 mRNA
CTD
PMID:31863870
NCBI chr13:66,224,219...66,377,728
Ensembl chr13:66,224,021...66,377,724
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Nme2
NME/NM23 nucleoside diphosphate kinase 2
affects expression
EXP
T-2 Toxin affects the expression of NME2 protein
CTD
PMID:26141394
NCBI chr10:78,898,097...78,903,514
Ensembl chr20:11,179,066...11,179,497 Ensembl chr10:11,179,066...11,179,497
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Nol9
nucleolar protein 9
increases expression
ISO
T-2 Toxin results in increased expression of NOL9 mRNA
CTD
PMID:31863870
NCBI chr 5:167,829,249...167,849,364
Ensembl chr 5:167,829,264...167,849,366
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Nolc1
nucleolar and coiled-body phosphoprotein 1
increases expression
ISO
T-2 Toxin results in increased expression of NOLC1 mRNA
CTD
PMID:34581912
NCBI chr 1:254,870,195...254,881,070
Ensembl chr 1:254,870,319...254,881,069
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Nop14
NOP14 nucleolar protein
increases expression
ISO
T-2 Toxin results in increased expression of NOP14 mRNA
CTD
PMID:34581912
NCBI chr14:80,305,912...80,327,053
Ensembl chr14:80,305,338...80,328,655
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Nop2
NOP2 nucleolar protein
increases expression
ISO
T-2 Toxin results in increased expression of NOP2 mRNA
CTD
PMID:34581912
NCBI chr 4:159,618,894...159,630,697
Ensembl chr 4:159,618,966...159,630,697
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Nos2
nitric oxide synthase 2
increases expression
ISO
T-2 Toxin results in increased expression of NOS2 mRNA
CTD
PMID:21112371 PMID:22960706 PMID:36775139
NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
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Nos3
nitric oxide synthase 3
decreases expression
ISO
T-2 Toxin results in decreased expression of NOS3 mRNA
CTD
PMID:22960706
NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:11,686,268...11,706,664
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Notch1
notch receptor 1
increases expression
EXP
T-2 Toxin results in increased expression of NOTCH1 mRNA
CTD
PMID:26141394
NCBI chr 3:29,676,040...29,721,613
Ensembl chr 3:29,676,171...29,721,613
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Npm1
nucleophosmin 1
affects expression
EXP
T-2 Toxin affects the expression of NPM1 protein
CTD
PMID:26141394
NCBI chr10:18,245,739...18,255,913
Ensembl chr10:18,245,740...18,256,024 Ensembl chr X:18,245,740...18,256,024
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Nptxr
neuronal pentraxin receptor
decreases expression
EXP
T-2 Toxin results in decreased expression of NPTXR mRNA
CTD
PMID:26141394
NCBI chr 7:113,217,046...113,235,122
Ensembl chr 7:113,217,050...113,235,156
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Nqo1
NAD(P)H quinone dehydrogenase 1
decreases expression increases expression
ISO EXP
T-2 Toxin results in decreased expression of NQO1 mRNA T-2 Toxin results in increased expression of NQO1 mRNA
CTD
PMID:20854872 PMID:26141394 PMID:33508416
NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260
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Nqo2
N-ribosyldihydronicotinamide:quinone dehydrogenase 2
increases expression
ISO
T-2 Toxin results in increased expression of NQO2 protein
CTD
PMID:34581912
NCBI chr17:31,114,825...31,144,062
Ensembl chr17:31,114,529...31,143,662
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Nr0b1
nuclear receptor subfamily 0, group B, member 1
decreases expression
ISO
T-2 Toxin results in decreased expression of NR0B1 mRNA
CTD
PMID:22982764
NCBI chr X:54,707,658...54,711,786
Ensembl chr X:54,707,639...54,712,083
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Nr4a1
nuclear receptor subfamily 4, group A, member 1
decreases expression
ISO
T-2 Toxin results in decreased expression of NR4A1 mRNA
CTD
PMID:31863870
NCBI chr 7:134,247,153...134,268,044
Ensembl chr 7:134,247,192...134,268,041
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Nr5a1
nuclear receptor subfamily 5, group A, member 1
decreases expression
ISO
T-2 Toxin results in decreased expression of NR5A1 mRNA
CTD
PMID:22982764
NCBI chr 3:42,874,505...42,896,109
Ensembl chr 3:42,875,221...42,896,046
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Nrf1
nuclear respiratory factor 1
decreases expression multiple interactions affects expression
ISO EXP
T-2 Toxin results in decreased expression of NRF1 protein T-2 Toxin results in decreased expression of NRF1 mRNA; T-2 Toxin results in decreased expression of NRF1 protein NFE2L2 protein affects the reaction [T-2 Toxin results in decreased expression of NRF1 mRNA]; NFE2L2 protein affects the reaction [T-2 Toxin results in decreased expression of NRF1 protein]; T-2 Toxin promotes the reaction [NRF1 protein binds to CYP1A1 promoter] T-2 Toxin affects the expression of NRF1 mRNA 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [T-2 Toxin results in decreased expression of NRF1 protein]
CTD
PMID:27363784 PMID:29870751 PMID:31470059 PMID:35842139
NCBI chr 4:59,632,366...59,738,166
Ensembl chr 4:59,632,372...59,738,353
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Nrip3
nuclear receptor interacting protein 3
increases expression
ISO
T-2 Toxin results in increased expression of NRIP3 mRNA
CTD
PMID:31863870
NCBI chr 1:163,789,738...163,815,036
Ensembl chr 1:173,224,532...173,251,769
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Nsfl1c
NSFL1 cofactor
multiple interactions
EXP
T-2 Toxin promotes the reaction [GABPA protein binds to NSFL1C]
CTD
PMID:36863559
NCBI chr 3:160,438,708...160,463,261
Ensembl chr 3:160,438,708...160,463,228
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Ntrk2
neurotrophic receptor tyrosine kinase 2
decreases expression
ISO
T-2 Toxin results in decreased expression of NTRK2 mRNA
CTD
PMID:31863870
NCBI chr17:5,560,558...5,875,899
Ensembl chr17:5,564,570...5,874,628
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Nucb1
nucleobindin 1
affects expression
EXP
T-2 Toxin affects the expression of NUCB1 protein
CTD
PMID:26141394
NCBI chr 1:95,968,325...95,999,183
Ensembl chr 1:105,104,793...105,135,837
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Nucb2
nucleobindin 2
decreases expression
ISO
T-2 Toxin results in decreased expression of NUCB2 mRNA
CTD
PMID:31863870
NCBI chr 1:180,185,121...180,221,644
Ensembl chr 1:180,199,551...180,230,116
G
Nuf2
NUF2 component of NDC80 kinetochore complex
decreases expression
ISO
T-2 Toxin results in decreased expression of NUF2 mRNA
CTD
PMID:34581912
NCBI chr13:84,226,448...84,290,957
Ensembl chr13:84,226,509...84,255,598
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Nup43
nucleoporin 43
increases expression
EXP
T-2 Toxin results in increased expression of NUP43 mRNA
CTD
PMID:26141394
NCBI chr 1:2,144,427...2,157,887
Ensembl chr 1:3,938,825...3,978,277
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Oat
ornithine aminotransferase
affects expression
EXP
T-2 Toxin affects the expression of OAT protein
CTD
PMID:26141394
NCBI chr 1:196,777,973...196,797,754
Ensembl chr 1:196,777,975...196,797,754
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Ocln
occludin
multiple interactions decreases expression
ISO
illite inhibits the reaction [T-2 Toxin results in decreased expression of OCLN mRNA] T-2 Toxin results in decreased expression of OCLN mRNA; T-2 Toxin results in decreased expression of OCLN protein
CTD
PMID:27153755 PMID:31170431
NCBI chr 2:33,391,303...33,442,207
Ensembl chr 2:33,391,303...33,430,411
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Opa1
OPA1, mitochondrial dynamin like GTPase
multiple interactions
EXP
PINK1 promotes the reaction [T-2 Toxin results in increased expression of OPA1 mRNA]
CTD
PMID:36863559
NCBI chr11:84,612,943...84,690,025
Ensembl chr11:84,615,340...84,689,955
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Ostm1
osteoclastogenesis associated transmembrane protein 1
decreases expression
ISO
T-2 Toxin results in decreased expression of OSTM1 mRNA
CTD
PMID:31863870
NCBI chr20:47,653,696...47,769,248
Ensembl chr20:47,653,670...47,769,237
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P4hb
prolyl 4-hydroxylase subunit beta
affects expression
EXP
T-2 Toxin affects the expression of P4HB protein
CTD
PMID:26141394
NCBI chr10:106,335,300...106,346,911
Ensembl chr10:106,335,300...106,346,911
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Pa2g4
proliferation-associated 2G4
affects expression
EXP
T-2 Toxin affects the expression of PA2G4 protein
CTD
PMID:26141394
NCBI chr 7:1,569,326...1,576,794
Ensembl chr 7:1,569,327...1,576,802
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Pafah1b2
platelet-activating factor acetylhydrolase 1b, catalytic subunit 2
increases expression
ISO
T-2 Toxin results in increased expression of PAFAH1B2 protein
CTD
PMID:34581912
NCBI chr 8:46,260,069...46,312,073
Ensembl chr 8:55,156,779...55,176,836
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Parg
poly (ADP-ribose) glycohydrolase
multiple interactions
EXP
T-2 Toxin promotes the reaction [GABPA protein binds to PARG]
CTD
PMID:36863559
NCBI chr16:7,442,696...7,550,585
Ensembl chr16:7,442,726...7,550,584
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Park7
Parkinsonism associated deglycase
affects expression
EXP
T-2 Toxin affects the expression of PARK7 protein
CTD
PMID:26141394
NCBI chr 5:166,636,551...166,659,825
Ensembl chr 5:166,636,552...166,659,825
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Parp1
poly (ADP-ribose) polymerase 1
increases expression
ISO
T-2 Toxin results in increased expression of PARP1 mRNA; T-2 Toxin results in increased expression of PARP1 protein
CTD
PMID:28697680 PMID:29432840
NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567
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Pax6
paired box 6
increases expression
ISO
T-2 Toxin results in increased expression of PAX6 mRNA
CTD
PMID:26314264
NCBI chr 3:112,590,034...112,611,771
Ensembl chr 3:112,590,391...112,611,763
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Pck2
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
decreases expression
ISO
T-2 Toxin results in decreased expression of PCK2 mRNA
CTD
PMID:31863870
NCBI chr15:32,997,853...33,006,691
Ensembl chr15:32,997,834...33,016,864
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Pcna
proliferating cell nuclear antigen
affects expression
EXP
T-2 Toxin affects the expression of PCNA protein
CTD
PMID:26141394
NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901
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Pcsk5
proprotein convertase subtilisin/kexin type 5
decreases expression
ISO
T-2 Toxin results in decreased expression of PCSK5 mRNA
CTD
PMID:31863870
NCBI chr 1:214,837,847...215,267,626
Ensembl chr 1:224,264,678...224,694,347
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Pcyox1l
prenylcysteine oxidase 1 like
decreases expression
ISO
T-2 Toxin results in decreased expression of PCYOX1L mRNA
CTD
PMID:31863870
NCBI chr18:57,420,971...57,431,632
Ensembl chr18:57,420,977...57,431,632
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Pdcd10
programmed cell death 10
affects expression
EXP
T-2 Toxin affects the expression of PDCD10 protein
CTD
PMID:26141394
NCBI chr 2:162,602,516...162,644,690
Ensembl chr 2:162,602,516...162,644,612
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Pdcd4
programmed cell death 4
increases expression decreases expression
EXP ISO
T-2 Toxin results in increased expression of PDCD4 mRNA T-2 Toxin results in decreased expression of PDCD4 mRNA
CTD
PMID:26141394 PMID:34581912
NCBI chr 1:262,912,659...262,949,581
Ensembl chr 1:262,926,656...262,950,189
G
Pdcd7
programmed cell death 7
increases expression
EXP
T-2 Toxin results in increased expression of PDCD7 mRNA
CTD
PMID:26141394
NCBI chr 8:74,757,768...74,772,495
Ensembl chr 8:74,757,768...74,781,634
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Pde10a
phosphodiesterase 10A
decreases expression
EXP
T-2 Toxin results in decreased expression of PDE10A mRNA
CTD
PMID:26141394
NCBI chr 1:51,765,743...52,218,086
Ensembl chr 1:54,317,732...54,764,051
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Pde4b
phosphodiesterase 4B
increases expression
ISO
T-2 Toxin results in increased expression of PDE4B mRNA
CTD
PMID:36775139
NCBI chr 5:122,028,956...122,598,267
Ensembl chr 5:122,135,174...122,598,267
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Pdgfa
platelet derived growth factor subunit A
increases expression
ISO
T-2 Toxin results in increased expression of PDGFA mRNA
CTD
PMID:34581912
NCBI chr12:20,759,366...20,780,337
Ensembl chr12:20,754,208...20,780,322
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Pdgfrl
platelet-derived growth factor receptor-like
decreases expression
ISO
T-2 Toxin results in decreased expression of PDGFRL mRNA
CTD
PMID:31863870
NCBI chr16:51,347,929...51,407,850
Ensembl chr16:58,051,440...58,111,327
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Pdhb
pyruvate dehydrogenase E1 subunit beta
affects expression
EXP
T-2 Toxin affects the expression of PDHB protein
CTD
PMID:26141394
NCBI chr15:16,752,561...16,758,503
Ensembl chr15:19,181,208...19,188,976
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Pdia3
protein disulfide isomerase family A, member 3
affects expression
EXP
T-2 Toxin affects the expression of PDIA3 protein
CTD
PMID:26141394
NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:128,841,917...128,867,327
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Pdia4
protein disulfide isomerase family A, member 4
decreases expression
ISO
T-2 Toxin results in decreased expression of PDIA4 mRNA
CTD
PMID:31863870
NCBI chr 4:78,134,144...78,153,191
Ensembl chr 4:78,134,144...78,153,191
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Pdlim1
PDZ and LIM domain 1
decreases expression
EXP
T-2 Toxin results in decreased expression of PDLIM1 mRNA
CTD
PMID:26141394
NCBI chr 1:248,991,818...249,040,409
Ensembl chr 1:248,991,818...249,047,379
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Pdrg1
p53 and DNA damage regulated 1
increases expression
EXP
T-2 Toxin results in increased expression of PDRG1 mRNA
CTD
PMID:26141394
NCBI chr 3:161,937,812...161,943,981
Ensembl chr 3:161,937,815...161,948,995
G
Pea15
proliferation and apoptosis adaptor protein 15
increases expression
ISO
T-2 Toxin results in increased expression of PEA15 mRNA
CTD
PMID:34581912
NCBI chr13:87,190,189...87,199,811
Ensembl chr13:87,187,295...87,199,859
G
Pes1
pescadillo ribosomal biogenesis factor 1
increases expression
ISO
T-2 Toxin results in increased expression of PES1 mRNA
CTD
PMID:34581912
NCBI chr14:83,074,346...83,090,726
Ensembl chr14:83,074,319...83,091,718
G
Pex5
peroxisomal biogenesis factor 5
multiple interactions increases expression
EXP
GABPA promotes the reaction [T-2 Toxin results in increased expression of PEX5 mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to PEX5]
CTD
PMID:36863559
NCBI chr 4:158,956,973...158,983,581
Ensembl chr 4:158,956,974...158,982,733
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Pfn1
profilin 1
affects expression
EXP
T-2 Toxin affects the expression of PFN1 protein
CTD
PMID:26141394
NCBI chr10:55,863,882...55,866,587
Ensembl chr10:55,863,881...55,868,611
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Pgam1
phosphoglycerate mutase 1
affects expression
EXP
T-2 Toxin affects the expression of PGAM1 protein
CTD
PMID:26141394
NCBI chr 1:250,673,152...250,680,762
Ensembl chr 1:250,673,049...250,690,203
G
Pgk1
phosphoglycerate kinase 1
affects expression
EXP
T-2 Toxin affects the expression of PGK1 protein
CTD
PMID:26141394
NCBI chr X:75,336,988...75,352,962
Ensembl chr X:75,336,687...75,352,959
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Pgls
6-phosphogluconolactonase
affects expression increases expression
EXP ISO
T-2 Toxin affects the expression of PGLS protein T-2 Toxin results in increased expression of PGLS protein
CTD
PMID:26141394 PMID:34581912
NCBI chr16:18,334,299...18,339,785
Ensembl chr16:18,334,299...18,339,785
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Pgr
progesterone receptor
multiple interactions
ISO
T-2 Toxin inhibits the reaction [[CGA protein co-treated with FSHB protein] results in increased expression of PGR mRNA]
CTD
PMID:30951242
NCBI chr 8:14,354,398...14,413,271
Ensembl chr 8:14,354,398...14,413,271
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Phb1
prohibitin 1
affects expression increases expression
EXP ISO
T-2 Toxin affects the expression of PHB1 protein T-2 Toxin results in increased expression of PHB1 mRNA
CTD
PMID:26141394 PMID:31863870
NCBI chr10:81,102,043...81,114,815
Ensembl chr10:81,102,028...81,116,233
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Phgdh
phosphoglycerate dehydrogenase
decreases expression
ISO
T-2 Toxin results in decreased expression of PHGDH mRNA
CTD
PMID:34581912
NCBI chr 2:188,595,700...188,624,789
Ensembl chr 2:188,595,700...188,624,789
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Phlda1
pleckstrin homology-like domain, family A, member 1
increases expression
ISO
T-2 Toxin results in increased expression of PHLDA1 mRNA
CTD
PMID:34581912
NCBI chr 7:48,853,690...48,855,894
Ensembl chr 7:48,853,260...48,857,542
G
Pik3cb
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
decreases expression
ISO
T-2 Toxin results in decreased expression of PIK3CB mRNA
CTD
PMID:34581912
NCBI chr 8:108,474,017...108,579,140
Ensembl chr 8:108,474,019...108,579,331
G
Pik3r2
phosphoinositide-3-kinase regulatory subunit 2
decreases expression
EXP
T-2 Toxin results in decreased expression of PIK3R2 mRNA
CTD
PMID:26141394
NCBI chr16:18,699,389...18,708,045
Ensembl chr16:18,699,448...18,709,665
G
Pik3r3
phosphoinositide-3-kinase regulatory subunit 3
increases expression
ISO
T-2 Toxin results in increased expression of PIK3R3 mRNA
CTD
PMID:34581912
NCBI chr 5:134,936,790...135,009,303
Ensembl chr 5:134,934,857...135,007,762
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Pink1
PTEN induced kinase 1
multiple interactions increases expression
EXP
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [T-2 Toxin results in increased expression of PINK1 protein]; NFE2L2 protein affects the reaction [T-2 Toxin results in increased expression of PINK1 protein]; PINK1 promotes the reaction [T-2 Toxin results in increased expression of DNM1L mRNA]; PINK1 promotes the reaction [T-2 Toxin results in increased expression of FIS1 mRNA]; PINK1 promotes the reaction [T-2 Toxin results in increased expression of MFN1 mRNA]; PINK1 promotes the reaction [T-2 Toxin results in increased expression of OPA1 mRNA] T-2 Toxin results in increased expression of PINK1 mRNA; T-2 Toxin results in increased expression of PINK1 protein
CTD
PMID:29870751 PMID:36863559
NCBI chr 5:155,813,838...155,825,950
Ensembl chr 5:155,813,838...155,825,950
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Pkib
cAMP-dependent protein kinase inhibitor beta
decreases expression
EXP
T-2 Toxin results in decreased expression of PKIB mRNA
CTD
PMID:26141394
NCBI chr20:37,511,564...37,608,607
Ensembl chr20:37,512,822...37,608,401
G
Pkig
cAMP-dependent protein kinase inhibitor gamma
affects expression
EXP
T-2 Toxin affects the expression of PKIG protein
CTD
PMID:26141394
NCBI chr 3:172,749,871...172,817,514
Ensembl chr 3:172,749,928...172,817,519
G
Pkm
pyruvate kinase M1/2
affects expression
EXP
T-2 Toxin affects the expression of PKM protein
CTD
PMID:26141394
NCBI chr 8:68,949,731...68,975,394
Ensembl chr 8:68,948,815...68,975,396
G
Plekha1
pleckstrin homology domain containing A1
decreases expression
ISO
T-2 Toxin results in decreased expression of PLEKHA1 mRNA
CTD
PMID:34581912
NCBI chr 1:185,427,982...185,479,157
Ensembl chr 1:194,851,547...194,909,413
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Plxna4
plexin A4
decreases expression
ISO
T-2 Toxin results in decreased expression of PLXNA4 mRNA
CTD
PMID:31863870
NCBI chr 4:61,687,483...62,129,467
Ensembl chr 4:61,687,510...62,129,445
G
Polr2e
RNA polymerase II, I and III subunit E
increases expression
ISO
T-2 Toxin results in increased expression of POLR2E mRNA
CTD
PMID:34581912
NCBI chr 7:10,317,332...10,321,280
Ensembl chr 7:10,317,389...10,321,276
G
Polr3c
RNA polymerase III subunit C
increases expression
ISO
T-2 Toxin results in increased expression of POLR3C mRNA
CTD
PMID:34581912
NCBI chr 2:186,935,038...186,950,962
Ensembl chr 2:186,935,038...186,950,962
G
Pop4
POP4 homolog, ribonuclease P/MRP subunit
increases expression
ISO
T-2 Toxin results in increased expression of POP4 mRNA
CTD
PMID:34581912
NCBI chr 1:100,096,722...100,105,056
Ensembl chr 1:100,096,723...100,105,104
G
Pou1f1
POU class 1 homeobox 1
increases expression
EXP
T-2 Toxin results in increased expression of POU1F1 mRNA
CTD
PMID:26141394
NCBI chr11:3,316,818...3,334,804
Ensembl chr11:16,763,552...16,781,292
G
Pparg
peroxisome proliferator-activated receptor gamma
increases expression
EXP
T-2 Toxin results in increased expression of PPARG mRNA
CTD
PMID:26141394
NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104
G
Ppargc1a
PPARG coactivator 1 alpha
decreases expression multiple interactions increases expression
ISO EXP
T-2 Toxin results in decreased expression of PPARGC1A protein NFE2L2 protein affects the reaction [T-2 Toxin results in decreased expression of PPARGC1A mRNA]; NFE2L2 protein affects the reaction [T-2 Toxin results in decreased expression of PPARGC1A protein] T-2 Toxin results in decreased expression of PPARGC1A mRNA; T-2 Toxin results in decreased expression of PPARGC1A protein T-2 Toxin results in increased expression of PPARGC1A mRNA 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [T-2 Toxin results in decreased expression of PPARGC1A protein]
CTD
PMID:27363784 PMID:29870751 PMID:35842139
NCBI chr14:63,073,505...63,729,215
Ensembl chr14:63,273,189...63,729,213
G
Ppargc1b
PPARG coactivator 1 beta
increases expression
EXP
T-2 Toxin results in increased expression of PPARGC1B mRNA
CTD
PMID:29870751
NCBI chr18:57,029,264...57,131,466
Ensembl chr18:57,029,275...57,131,466
G
Ppcs
phosphopantothenoylcysteine synthetase
increases expression
ISO
T-2 Toxin results in increased expression of PPCS mRNA
CTD
PMID:31863870
NCBI chr 5:138,308,394...138,312,047
Ensembl chr 5:138,308,397...138,312,012
G
Ppia
peptidylprolyl isomerase A
affects expression
EXP
T-2 Toxin affects the expression of PPIA protein
CTD
PMID:26141394
NCBI chr14:85,491,223...85,496,884
Ensembl chr14:85,492,484...85,497,115
G
Ppp1r10
protein phosphatase 1, regulatory subunit 10
increases expression
ISO
T-2 Toxin results in increased expression of PPP1R10 mRNA
CTD
PMID:34581912
NCBI chr20:2,827,802...2,842,418
Ensembl chr20:2,827,802...2,842,418
G
Ppp3cb
protein phosphatase 3 catalytic subunit beta
decreases expression
ISO
T-2 Toxin results in decreased expression of PPP3CB mRNA
CTD
PMID:34581912
NCBI chr15:3,809,182...3,854,204
Ensembl chr15:3,809,262...3,854,203
G
Pprc1
PPARG related coactivator 1
increases expression
EXP
T-2 Toxin results in increased expression of PPRC1 mRNA
CTD
PMID:29870751
NCBI chr 1:244,901,985...244,918,587
Ensembl chr 1:254,851,164...254,867,570
G
Prcp
prolylcarboxypeptidase
decreases expression
ISO
T-2 Toxin results in decreased expression of PRCP mRNA
CTD
PMID:31863870
NCBI chr 1:156,343,894...156,396,295
Ensembl chr 1:156,343,896...156,396,939
G
Prdx3
peroxiredoxin 3
affects expression decreases expression
EXP ISO
T-2 Toxin affects the expression of PRDX3 protein T-2 Toxin results in decreased expression of PRDX3 mRNA; T-2 Toxin results in decreased expression of PRDX3 protein
CTD
PMID:26141394 PMID:34581912
NCBI chr 1:269,987,691...270,000,111
Ensembl chr 1:269,987,685...270,000,300
G
Prdx4
peroxiredoxin 4
affects expression
EXP
T-2 Toxin affects the expression of PRDX4 protein
CTD
PMID:26141394
NCBI chr X:40,026,762...40,044,066
Ensembl chr X:43,876,417...43,893,812
G
Prelp
proline and arginine rich end leucine rich repeat protein
decreases expression
ISO
T-2 Toxin results in decreased expression of PRELP mRNA
CTD
PMID:31863870
NCBI chr13:47,920,480...47,943,547
Ensembl chr13:47,922,590...47,932,324
G
Prickle2
prickle planar cell polarity protein 2
increases expression
ISO
T-2 Toxin results in increased expression of PRICKLE2 mRNA
CTD
PMID:31863870
NCBI chr 4:124,869,655...125,214,862
Ensembl chr 4:126,426,771...126,772,008
G
Prkaa2
protein kinase AMP-activated catalytic subunit alpha 2
multiple interactions
EXP
[Selenium deficiency co-treated with T-2 Toxin] results in decreased expression of PRKAA2 mRNA
CTD
PMID:38796086
NCBI chr 5:125,036,945...125,109,010
Ensembl chr 5:125,042,179...125,108,324
G
Prkcb
protein kinase C, beta
decreases expression
EXP
T-2 Toxin results in decreased expression of PRKCB mRNA
CTD
PMID:26141394
NCBI chr 1:186,263,397...186,594,743
Ensembl chr 1:186,263,447...186,594,740
G
Prkcz
protein kinase C, zeta
decreases expression
EXP
T-2 Toxin results in decreased expression of PRKCZ mRNA
CTD
PMID:26141394
NCBI chr 5:171,101,774...171,212,694
Ensembl chr 5:171,101,774...171,212,674
G
Prkn
parkin RBR E3 ubiquitin protein ligase
increases expression
EXP
T-2 Toxin results in increased expression of PRKN mRNA; T-2 Toxin results in increased expression of PRKN protein
CTD
PMID:29870751
NCBI chr 1:51,236,410...52,430,242
Ensembl chr 1:51,210,330...52,430,304
G
Prmt5
protein arginine methyltransferase 5
increases expression
ISO
T-2 Toxin results in increased expression of PRMT5 mRNA
CTD
PMID:34581912
NCBI chr15:31,938,927...31,948,318
Ensembl chr15:31,938,719...31,948,426
G
Prpf6
pre-mRNA processing factor 6
increases expression
ISO
T-2 Toxin results in increased expression of PRPF6 mRNA
CTD
PMID:34581912
NCBI chr 3:189,084,465...189,148,705
Ensembl chr 3:189,081,794...189,152,786
G
Psat1
phosphoserine aminotransferase 1
decreases expression
ISO
T-2 Toxin results in decreased expression of PSAT1 mRNA
CTD
PMID:31863870 PMID:34581912
NCBI chr 1:222,623,553...222,646,187
Ensembl chr 1:222,623,556...222,655,693
G
Psma4
proteasome 20S subunit alpha 4
affects expression
EXP
T-2 Toxin affects the expression of PSMA4 protein
CTD
PMID:26141394
NCBI chr 8:55,340,431...55,347,893
Ensembl chr 8:64,236,783...64,243,979
G
Psma6
proteasome 20S subunit alpha 6
affects expression
EXP
T-2 Toxin affects the expression of PSMA6 protein
CTD
PMID:26141394
NCBI chr 6:72,765,534...72,796,554
Ensembl chr 6:78,500,736...78,531,717
G
Psmb3
proteasome 20S subunit beta 3
affects expression
EXP
T-2 Toxin affects the expression of PSMB3 protein
CTD
PMID:26141394
NCBI chr10:83,193,787...83,200,883
Ensembl chr10:83,193,787...83,200,883
G
Psmb7
proteasome 20S subunit beta 7
affects expression
EXP
T-2 Toxin affects the expression of PSMB7 protein
CTD
PMID:26141394
NCBI chr 3:42,767,500...42,827,470
Ensembl chr 3:42,767,501...42,827,601
G
Psmc2
proteasome 26S subunit, ATPase 2
increases expression
ISO
T-2 Toxin results in increased expression of PSMC2 mRNA; T-2 Toxin results in increased expression of PSMC2 protein
CTD
PMID:34581912
NCBI chr 4:13,255,850...13,270,160
Ensembl chr 4:14,148,090...14,162,390
G
Psmd9
proteasome 26S subunit, non-ATPase 9
increases expression
EXP
T-2 Toxin results in increased expression of PSMD9 mRNA
CTD
PMID:26141394
NCBI chr12:33,337,182...33,357,468
Ensembl chr12:38,998,030...39,018,679
G
Psme3
proteasome activator subunit 3
increases expression
ISO
T-2 Toxin results in increased expression of PSME3 protein
CTD
PMID:34581912
NCBI chr10:86,757,933...86,765,719
Ensembl chr10:86,757,899...86,818,033
G
Ptgis
prostaglandin I2 synthase
decreases expression
ISO
T-2 Toxin results in decreased expression of PTGIS mRNA
CTD
PMID:31863870
NCBI chr 3:176,347,589...176,383,251
Ensembl chr 3:176,335,437...176,407,650
G
Ptgs2
prostaglandin-endoperoxide synthase 2
increases expression multiple interactions
ISO
T-2 Toxin results in increased expression of PTGS2 mRNA; T-2 Toxin results in increased expression of PTGS2 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [T-2 Toxin results in increased expression of PTGS2 mRNA]; Minocycline inhibits the reaction [T-2 Toxin results in increased expression of PTGS2 mRNA]; Minocycline inhibits the reaction [T-2 Toxin results in increased expression of PTGS2 protein]; pyrazolanthrone inhibits the reaction [T-2 Toxin results in increased expression of PTGS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [T-2 Toxin results in increased expression of PTGS2 mRNA]
CTD
PMID:36115646 PMID:36775139
NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
G
Ptprc
protein tyrosine phosphatase, receptor type, C
decreases expression
ISO
T-2 Toxin results in decreased expression of PTPRC mRNA
CTD
PMID:34581912
NCBI chr13:52,147,717...52,259,810
Ensembl chr13:52,147,717...52,259,746
G
Ptprf
protein tyrosine phosphatase, receptor type, F
increases expression
ISO
T-2 Toxin results in increased expression of PTPRF mRNA
CTD
PMID:34581912
NCBI chr 5:137,027,376...137,109,405
Ensembl chr 5:137,028,164...137,095,426
G
Pxn
paxillin
increases expression
ISO
T-2 Toxin results in increased expression of PXN mRNA
CTD
PMID:34581912
NCBI chr12:46,721,546...46,768,706
Ensembl chr12:46,721,546...46,768,697
G
Pyy
peptide YY
increases expression
ISO
T-2 Toxin results in increased expression of PYY protein alternative form
CTD
PMID:29689362
NCBI chr10:87,561,347...87,562,470
Ensembl chr10:87,561,353...87,562,206
G
Qsox1
quiescin sulfhydryl oxidase 1
decreases expression
EXP
T-2 Toxin results in decreased expression of QSOX1 mRNA
CTD
PMID:26141394
NCBI chr13:67,949,780...67,987,434
Ensembl chr13:70,500,060...70,537,733
G
Qsox2
quiescin sulfhydryl oxidase 2
decreases expression
EXP
T-2 Toxin results in decreased expression of QSOX2 mRNA
CTD
PMID:26141394
NCBI chr 3:9,034,994...9,064,649
Ensembl chr 3:29,433,091...29,463,036
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Rab20
RAB20, member RAS oncogene family
increases expression
ISO
T-2 Toxin results in increased expression of RAB20 mRNA
CTD
PMID:31863870
NCBI chr16:84,721,427...84,745,610
Ensembl chr16:84,721,427...84,745,610
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Rab25
RAB25, member RAS oncogene family
increases expression
EXP
T-2 Toxin results in increased expression of RAB25 mRNA
CTD
PMID:26141394
NCBI chr 2:174,000,323...174,006,422
Ensembl chr 2:176,298,124...176,304,221
G
Rab27a
RAB27A, member RAS oncogene family
decreases expression
EXP
T-2 Toxin results in decreased expression of RAB27A mRNA
CTD
PMID:26141394
NCBI chr 8:82,663,373...82,717,267
Ensembl chr 8:82,663,276...82,717,262
G
Ramp1
receptor activity modifying protein 1
decreases expression
ISO
T-2 Toxin results in decreased expression of RAMP1 mRNA
CTD
PMID:31863870
NCBI chr 9:99,213,031...99,263,696
G
Ranbp1
RAN binding protein 1
affects expression
EXP
T-2 Toxin affects the expression of RANBP1 protein
CTD
PMID:26141394
NCBI chr11:96,246,912...96,255,145
Ensembl chr11:96,246,740...96,255,145
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Rasal3
RAS protein activator like 3
increases expression
EXP
T-2 Toxin results in increased expression of RASAL3 mRNA
CTD
PMID:26141394
NCBI chr 7:11,396,554...11,411,347
Ensembl chr 7:12,047,090...12,061,883
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Rasd1
ras related dexamethasone induced 1
decreases expression
EXP
T-2 Toxin results in decreased expression of RASD1 mRNA
CTD
PMID:26141394
NCBI chr10:45,265,975...45,275,279
Ensembl chr10:45,265,979...45,267,710
G
Rassf1
Ras association domain family member 1
increases expression
EXP
T-2 Toxin results in increased expression of RASSF1 mRNA
CTD
PMID:26141394
NCBI chr 8:117,103,665...117,114,805
Ensembl chr 8:117,103,362...117,114,805
G
Rassf4
Ras association domain family member 4
decreases expression
EXP
T-2 Toxin results in decreased expression of RASSF4 mRNA
CTD
PMID:26141394
NCBI chr 4:151,569,984...151,605,203
Ensembl chr 4:151,569,984...151,604,883
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Rb1
RB transcriptional corepressor 1
decreases phosphorylation decreases expression
EXP
T-2 Toxin results in decreased phosphorylation of RB1 protein T-2 Toxin results in decreased expression of RB1 mRNA
CTD
PMID:29567467
NCBI chr15:54,780,858...54,911,989
Ensembl chr15:54,780,858...54,911,857
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Rbks
ribokinase
increases expression
EXP
T-2 Toxin results in increased expression of RBKS mRNA
CTD
PMID:26141394
NCBI chr 6:30,467,724...30,544,284
Ensembl chr 6:30,467,726...30,544,294
G
Rbpms2
RNA binding protein, mRNA processing factor 2
decreases expression
ISO
T-2 Toxin results in decreased expression of RBPMS2 mRNA
CTD
PMID:31863870
NCBI chr 8:75,048,159...75,079,393
Ensembl chr 8:75,048,263...75,079,396
G
Rcn1
reticulocalbin 1
affects expression
EXP
T-2 Toxin affects the expression of RCN1 protein
CTD
PMID:26141394
NCBI chr 3:91,841,052...91,855,295
Ensembl chr 3:112,295,838...112,310,082
G
Rela
RELA proto-oncogene, NF-kB subunit
multiple interactions increases phosphorylation increases expression affects localization
EXP ISO
T-2 Toxin promotes the reaction [RELA protein binds to AKNA promoter] 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [T-2 Toxin results in increased phosphorylation of RELA protein]; BTG2 protein affects the reaction [T-2 Toxin results in increased phosphorylation of RELA protein] T-2 Toxin results in increased expression of RELA mRNA T-2 Toxin affects the localization of RELA protein modified form
CTD
PMID:29079362 PMID:34581912 PMID:39147216
NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
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Relb
RELB proto-oncogene, NF-kB subunit
increases expression
ISO
T-2 Toxin results in increased expression of RELB mRNA
CTD
PMID:36775139
NCBI chr 1:88,385,717...88,413,380
Ensembl chr 1:88,385,717...88,413,420
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Reln
reelin
increases expression
ISO
T-2 Toxin results in increased expression of RELN mRNA
CTD
PMID:26314264
NCBI chr 4:13,628,440...14,055,201
Ensembl chr 4:13,628,399...14,055,162
G
Rgs1
regulator of G-protein signaling 1
increases expression
ISO
T-2 Toxin results in increased expression of RGS1 mRNA
CTD
PMID:39147216
NCBI chr13:58,568,844...58,573,187
Ensembl chr13:58,568,844...58,573,187
G
Rgs12
regulator of G-protein signaling 12
decreases expression
EXP
T-2 Toxin results in decreased expression of RGS12 mRNA
CTD
PMID:26141394
NCBI chr14:79,940,561...80,048,637
Ensembl chr14:79,940,565...80,034,859
G
Rgs2
regulator of G-protein signaling 2
increases expression
EXP
T-2 Toxin results in increased expression of RGS2 mRNA
CTD
PMID:26141394
NCBI chr13:58,350,063...58,352,666
Ensembl chr13:58,349,163...58,352,697
G
Rgs4
regulator of G-protein signaling 4
increases expression
EXP
T-2 Toxin results in increased expression of RGS4 mRNA
CTD
PMID:26141394
NCBI chr13:84,469,593...84,475,884
Ensembl chr13:84,469,593...84,475,884
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Rheb
Ras homolog, mTORC1 binding
increases expression multiple interactions
ISO
T-2 Toxin results in increased expression of RHEB mRNA; T-2 Toxin results in increased expression of RHEB protein MIR155 mRNA inhibits the reaction [T-2 Toxin results in increased expression of RHEB mRNA]; MIR155 mRNA inhibits the reaction [T-2 Toxin results in increased expression of RHEB protein]; RHEB protein promotes the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; RHEB protein promotes the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; RHEB protein promotes the reaction [T-2 Toxin results in increased expression of TNF mRNA]
CTD
PMID:32240701
NCBI chr 4:11,012,173...11,053,860
Ensembl chr 4:11,012,643...11,053,931
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Rhob
ras homolog family member B
increases expression
ISO
T-2 Toxin results in increased expression of RHOB mRNA
CTD
PMID:34581912
NCBI chr 6:37,083,030...37,085,204
Ensembl chr 6:37,075,015...37,112,772
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Rhoh
ras homolog family member H
increases expression
EXP
T-2 Toxin results in increased expression of RHOH mRNA
CTD
PMID:26141394
NCBI chr14:42,694,860...42,725,690
Ensembl chr14:42,693,413...42,749,967
G
Ripk3
receptor-interacting serine-threonine kinase 3
increases phosphorylation
EXP
T-2 Toxin results in increased phosphorylation of RIPK3 protein
CTD
PMID:39966150
NCBI chr15:33,253,071...33,262,025
Ensembl chr15:33,253,071...33,262,025
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Rlig1
RNA 5'-phosphate and 3'-OH ligase 1
increases expression
ISO
T-2 Toxin results in increased expression of RLIG1 mRNA
CTD
PMID:31863870
NCBI chr 7:37,284,545...37,295,858
Ensembl chr 7:37,284,620...37,298,044
G
Rp9
RP9, pre-mRNA splicing factor
increases expression
ISO
T-2 Toxin results in increased expression of RP9 mRNA
CTD
PMID:34581912
NCBI chr 8:29,218,564...29,281,211
Ensembl chr 8:29,217,346...29,281,150
G
Rpap1
RNA polymerase II associated protein 1
increases expression
ISO
T-2 Toxin results in increased expression of RPAP1 mRNA
CTD
PMID:34581912
NCBI chr 3:106,746,642...106,768,182
Ensembl chr 3:127,110,550...127,221,952
G
Rpia
ribose 5-phosphate isomerase A
decreases expression
EXP
T-2 Toxin results in decreased expression of RPIA mRNA
CTD
PMID:26141394
NCBI chr 4:104,282,081...104,307,732
Ensembl chr 4:104,282,081...104,307,718
G
Rplp2
ribosomal protein lateral stalk subunit P2
affects expression
EXP
T-2 Toxin affects the expression of RPLP2 protein
CTD
PMID:26141394
NCBI chr 1:205,975,598...205,978,192
Ensembl chr 1:205,975,894...205,978,191
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Rpn2
ribophorin II
decreases expression
ISO
T-2 Toxin results in decreased expression of RPN2 mRNA
CTD
PMID:31863870
NCBI chr 3:166,361,955...166,409,272
Ensembl chr 3:166,362,049...166,409,922
G
Rpp21
ribonuclease P/MRP subunit p21
increases expression
ISO
T-2 Toxin results in increased expression of RPP21 mRNA
CTD
PMID:34581912
NCBI chr20:1,986,225...2,025,308
Ensembl chr20:2,023,186...2,025,308
G
Rpp25
ribonuclease P and MRP subunit p25
increases expression
ISO
T-2 Toxin results in increased expression of RPP25 mRNA
CTD
PMID:34581912
NCBI chr 8:66,803,262...66,804,642
Ensembl chr 8:66,803,212...66,810,550
G
Rpp40
ribonuclease P/MRP subunit p40
increases expression
ISO
T-2 Toxin results in increased expression of RPP40 mRNA
CTD
PMID:34581912
NCBI chr17:29,153,203...29,162,241
Ensembl chr17:29,153,180...29,162,241
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Rps21-ps1
ribosomal protein S21, pseudogene 1
affects expression
EXP
T-2 Toxin affects the expression of RPS21 protein
CTD
PMID:26141394
NCBI chr 5:158,670,141...158,670,484
Ensembl chr 5:158,670,116...158,670,490
G
Rps6ka5
ribosomal protein S6 kinase A5
decreases expression
ISO
T-2 Toxin results in decreased expression of RPS6KA5 mRNA
CTD
PMID:34581912
NCBI chr 6:125,558,434...125,736,576
Ensembl chr 6:125,558,434...125,735,856
G
Rpsa
ribosomal protein SA
affects expression
EXP
T-2 Toxin affects the expression of RPSA protein
CTD
PMID:26141394
NCBI chr 8:128,728,761...128,732,736
Ensembl chr 8:128,728,862...128,732,737
G
Runx2
RUNX family transcription factor 2
decreases expression multiple interactions
ISO
T-2 Toxin results in decreased expression of RUNX2 mRNA; T-2 Toxin results in decreased expression of RUNX2 protein 3-methyladenine promotes the reaction [T-2 Toxin results in decreased expression of RUNX2 protein]
CTD
PMID:35289972 PMID:36402210
NCBI chr 9:23,661,278...23,990,248
Ensembl chr 9:23,664,952...23,990,027
G
Ruvbl1
RuvB-like AAA ATPase 1
increases expression
ISO
T-2 Toxin results in increased expression of RUVBL1 mRNA
CTD
PMID:31863870 PMID:34581912
NCBI chr 4:122,489,754...122,524,666
Ensembl chr 4:122,489,680...122,524,665
G
Ruvbl2
RuvB-like AAA ATPase 2
affects expression increases expression
EXP ISO
T-2 Toxin affects the expression of RUVBL2 protein T-2 Toxin results in increased expression of RUVBL2 mRNA
CTD
PMID:26141394 PMID:31863870
NCBI chr 1:105,038,487...105,051,851
Ensembl chr 1:105,038,174...105,051,720
G
Safb
scaffold attachment factor B
increases expression
EXP
T-2 Toxin results in increased expression of SAFB mRNA
CTD
PMID:26141394
NCBI chr 9:1,504,657...1,525,545
Ensembl chr 9:1,504,456...1,525,781
G
Sap30bp
SAP30 binding protein
increases expression
ISO
T-2 Toxin results in increased expression of SAP30BP mRNA
CTD
PMID:34581912
NCBI chr10:101,664,714...101,697,430
Ensembl chr10:101,664,697...101,697,429
G
Scpep1
serine carboxypeptidase 1
decreases expression
ISO
T-2 Toxin results in decreased expression of SCPEP1 mRNA
CTD
PMID:31863870
NCBI chr10:73,703,275...73,732,892
Ensembl chr10:74,200,491...74,230,241
G
Sdha
succinate dehydrogenase complex flavoprotein subunit A
increases expression
EXP
T-2 Toxin results in increased expression of SDHA mRNA
CTD
PMID:29870751
NCBI chr 1:30,764,553...30,789,523
Ensembl chr 1:30,764,590...30,790,121
G
Sdhb
succinate dehydrogenase complex iron sulfur subunit B
increases expression
EXP
T-2 Toxin results in increased expression of SDHB mRNA
CTD
PMID:29870751
NCBI chr 5:158,547,775...158,568,589
Ensembl chr 5:158,547,689...158,569,667
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Selenos
selenoprotein S
increases expression
ISO
T-2 Toxin results in increased expression of SELS mRNA
CTD
PMID:34581912
NCBI chr 1:129,070,240...129,080,007
Ensembl chr 1:129,070,230...129,077,991
G
Sema3f
semaphorin 3F
decreases expression
EXP
T-2 Toxin results in decreased expression of SEMA3F mRNA
CTD
PMID:26141394
NCBI chr 8:117,236,269...117,265,206
Ensembl chr 8:117,236,269...117,265,206
G
Serf2
small EDRK-rich factor 2
decreases expression
ISO
T-2 Toxin results in decreased expression of SERF2 mRNA
CTD
PMID:39147216
NCBI chr 3:128,880,681...128,884,457
Ensembl chr 3:128,880,681...128,884,457
G
Serpina3n
serpin family A member 3N
decreases expression
ISO
T-2 Toxin results in decreased expression of SERPINA3 mRNA
CTD
PMID:31863870
NCBI chr 6:129,088,392...129,095,950
Ensembl chr 6:129,088,398...129,097,415
G
Serpinb9
serpin family B member 9
increases expression
ISO
T-2 Toxin results in increased expression of SERPINB9 protein
CTD
PMID:34581912
NCBI chr17:31,628,887...31,652,003
Ensembl chr17:31,629,392...31,651,974
G
Serpine2
serpin family E member 2
decreases expression
EXP
T-2 Toxin results in decreased expression of SERPINE2 mRNA
CTD
PMID:26141394
NCBI chr 9:88,573,138...88,637,252
Ensembl chr 9:88,573,149...88,637,202
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Set
Set nuclear proto-oncogene
affects expression
EXP
T-2 Toxin affects the expression of SET protein
CTD
PMID:26141394
NCBI chr 3:33,732,319...33,743,433
G
Setdb1
SET domain bifurcated histone lysine methyltransferase 1
increases expression
EXP
T-2 Toxin results in increased expression of SETDB1 mRNA
CTD
PMID:26141394
NCBI chr 2:185,587,722...185,619,084
Ensembl chr 2:185,587,722...185,618,982
G
Sf3b2
splicing factor 3b, subunit 2
increases expression
ISO
T-2 Toxin results in increased expression of SF3B2 mRNA
CTD
PMID:34581912
NCBI chr 1:211,999,777...212,040,686
Ensembl chr 1:211,999,778...212,020,113
G
Sgk1
serum/glucocorticoid regulated kinase 1
increases expression
ISO
T-2 Toxin results in increased expression of SGK1 mRNA
CTD
PMID:34581912
NCBI chr 1:24,799,391...24,916,886
Ensembl chr 1:24,799,396...24,807,231
G
Sgms1
sphingomyelin synthase 1
decreases expression
EXP
T-2 Toxin results in decreased expression of SGMS1 mRNA
CTD
PMID:26141394
NCBI chr 1:239,409,991...239,681,195
Ensembl chr 1:239,409,991...239,505,774
G
Sh3gl1
SH3 domain containing GRB2 like 1, endophilin A2
affects expression
EXP
T-2 Toxin affects the expression of SH3GL1 protein
CTD
PMID:26141394
NCBI chr 9:842,285...869,753
Ensembl chr 9:928,563...956,890
G
Sirt1
sirtuin 1
multiple interactions
EXP
[Selenium deficiency co-treated with T-2 Toxin] results in decreased expression of SIRT1 mRNA
CTD
PMID:38796086
NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,305,476...25,328,000
G
Skp1
S-phase kinase-associated protein 1
affects expression
EXP
T-2 Toxin affects the expression of SKP1 protein
CTD
PMID:26141394
NCBI chr10:36,898,670...36,917,828
Ensembl chr10:36,903,078...36,918,308
G
Slc17a5
solute carrier family 17 member 5
decreases expression
ISO
T-2 Toxin results in decreased expression of SLC17A5 mRNA
CTD
PMID:31863870
NCBI chr 8:88,274,497...88,309,734
Ensembl chr 8:88,274,721...88,309,664
G
Slc17a6
solute carrier family 17 member 6
decreases expression
ISO
T-2 Toxin results in decreased expression of SLC17A6 mRNA
CTD
PMID:26314264
NCBI chr 1:110,348,447...110,388,499
Ensembl chr 1:110,348,447...110,388,498
G
Slc1a5
solute carrier family 1 member 5
decreases expression
ISO
T-2 Toxin results in decreased expression of SLC1A5 mRNA
CTD
PMID:31863870
NCBI chr 1:86,584,949...86,599,052
Ensembl chr 1:86,584,949...86,599,054
G
Slc27a5
solute carrier family 27 member 5
increases expression
EXP
T-2 Toxin results in increased expression of SLC27A5 mRNA
CTD
PMID:26141394
NCBI chr 1:82,688,742...82,699,335
Ensembl chr 1:82,688,750...82,699,358
G
Slc29a4
solute carrier family 29 member 4
decreases expression
EXP
T-2 Toxin results in decreased expression of SLC29A4 mRNA
CTD
PMID:26141394
NCBI chr12:11,853,540...11,884,660
Ensembl chr12:16,967,047...16,988,338
G
Slc35g1
solute carrier family 35, member G1
decreases expression
ISO
T-2 Toxin results in decreased expression of SLC35G1 mRNA
CTD
PMID:31863870
NCBI chr 1:236,163,593...236,172,115
Ensembl chr 1:245,575,996...245,584,529
G
Slc37a3
solute carrier family 37, member 3
decreases expression
ISO
T-2 Toxin results in decreased expression of SLC37A3 mRNA
CTD
PMID:31863870
NCBI chr 4:68,109,314...68,153,590
Ensembl chr 4:69,076,149...69,120,371
G
Slc38a1
solute carrier family 38, member 1
decreases expression
ISO
T-2 Toxin results in decreased expression of SLC38A1 mRNA
CTD
PMID:31863870
NCBI chr 7:129,612,414...129,681,727
Ensembl chr 7:129,617,387...129,681,778
G
Slc7a2
solute carrier family 7 member 2
decreases expression
ISO
T-2 Toxin results in decreased expression of SLC7A2 mRNA
CTD
PMID:31863870
NCBI chr16:58,115,991...58,174,256
Ensembl chr16:58,120,968...58,174,256
G
Slit1
slit guidance ligand 1
decreases expression
EXP
T-2 Toxin results in decreased expression of SLIT1 mRNA
CTD
PMID:26141394
NCBI chr 1:250,358,917...250,507,476
Ensembl chr 1:250,358,919...250,507,476
G
Smarca1
SNF2 related chromatin remodeling ATPase 1
decreases expression
ISO
T-2 Toxin results in decreased expression of SMARCA1 mRNA
CTD
PMID:34581912
NCBI chr X:131,858,148...131,944,639
Ensembl chr X:131,859,088...131,944,282
G
Smoc1
SPARC related modular calcium binding 1
decreases expression
ISO
T-2 Toxin results in decreased expression of SMOC1 mRNA
CTD
PMID:31863870
NCBI chr 6:106,432,592...106,593,956
Ensembl chr 6:106,432,603...106,593,956
G
Sms
spermine synthase
increases expression
ISO
T-2 Toxin results in increased expression of SMS mRNA
CTD
PMID:31863870
NCBI chr X:41,331,693...41,387,713
Ensembl chr X:41,331,799...41,387,712
G
Snrpf
small nuclear ribonucleoprotein polypeptide F
affects expression
EXP
T-2 Toxin affects the expression of SNRPF protein
CTD
PMID:26141394
NCBI chr 7:30,017,460...30,024,162
Ensembl chr 7:30,017,460...30,024,162
G
Snu13
small nuclear ribonucleoprotein 13
increases expression
ISO
T-2 Toxin results in increased expression of SNU13 mRNA
CTD
PMID:34581912
NCBI chr 7:115,445,415...115,451,008
Ensembl chr 1:269,702,002...269,703,004 Ensembl chr 7:269,702,002...269,703,004
G
Socs1
suppressor of cytokine signaling 1
increases expression multiple interactions
ISO
T-2 Toxin results in increased expression of SOCS1 mRNA MIR155 mRNA inhibits the reaction [T-2 Toxin results in increased expression of SOCS1 mRNA]
CTD
PMID:32240701
NCBI chr10:5,389,574...5,391,265
Ensembl chr10:5,389,334...5,391,847
G
Sod1
superoxide dismutase 1
increases expression decreases expression decreases activity affects expression
ISO EXP
T-2 Toxin results in increased expression of SOD1 mRNA T-2 Toxin results in decreased expression of SOD1 mRNA T-2 Toxin results in decreased activity of SOD1 protein T-2 Toxin affects the expression of SOD1 protein
CTD
PMID:26138683 PMID:26141394 PMID:27842451 PMID:33508416
NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399
G
Sod2
superoxide dismutase 2
decreases expression increases expression
EXP ISO
T-2 Toxin results in decreased expression of SOD2 mRNA T-2 Toxin results in increased expression of SOD2 mRNA
CTD
PMID:26141394 PMID:29870751 PMID:30091165
NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168
G
Sp1
Sp1 transcription factor
multiple interactions
ISO
T-2 Toxin promotes the reaction [SP1 protein binds to CYP1A1 promoter]
CTD
PMID:31470059
NCBI chr 7:135,419,864...135,450,513
Ensembl chr 7:135,420,050...135,450,513
G
Sp7
Sp7 transcription factor
decreases expression multiple interactions
ISO
T-2 Toxin results in decreased expression of SP7 protein 3-methyladenine promotes the reaction [T-2 Toxin results in decreased expression of SP7 protein]
CTD
PMID:35289972 PMID:36402210
NCBI chr 7:135,363,193...135,373,376
Ensembl chr 7:135,363,199...135,373,559
G
Spc25
SPC25 component of NDC80 kinetochore complex
decreases expression
ISO
T-2 Toxin results in decreased expression of SPC25 mRNA
CTD
PMID:34581912
NCBI chr 3:74,337,872...74,396,825
Ensembl chr 3:74,383,548...74,396,718
G
Spcs3
signal peptidase complex subunit 3
decreases expression
ISO
T-2 Toxin results in decreased expression of SPCS3 mRNA
CTD
PMID:31863870
NCBI chr16:44,038,421...44,043,855
Ensembl chr16:44,038,278...44,046,394
G
Sphk1
sphingosine kinase 1
increases expression
ISO
T-2 Toxin results in increased expression of SPHK1 mRNA
CTD
PMID:34581912
NCBI chr10:102,257,413...102,263,086
Ensembl chr10:102,258,975...102,263,082
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Spi1
Spi-1 proto-oncogene
increases expression
ISO
T-2 Toxin results in increased expression of SPI1 mRNA
CTD
PMID:34581912
NCBI chr 3:97,529,509...97,548,204
Ensembl chr 3:97,527,572...97,549,540
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Sqstm1
sequestosome 1
increases expression
ISO
T-2 Toxin results in increased expression of SQSTM1 mRNA T-2 Toxin results in increased expression of SQSTM1 protein
CTD
PMID:34581912 PMID:35289972
NCBI chr10:35,026,598...35,037,750
Ensembl chr10:35,026,598...35,037,750
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Srfbp1
serum response factor binding protein 1
increases expression
ISO
T-2 Toxin results in increased expression of SRFBP1 mRNA
CTD
PMID:31863870
NCBI chr18:48,118,740...48,139,824
Ensembl chr18:48,117,375...48,140,864
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Ssr3
signal sequence receptor subunit 3
decreases expression
ISO
T-2 Toxin results in decreased expression of SSR3 mRNA
CTD
PMID:31863870
NCBI chr 2:149,605,005...149,625,069
Ensembl chr 2:151,906,149...151,935,170
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Sstr1
somatostatin receptor 1
decreases expression
EXP
T-2 Toxin results in decreased expression of SSTR1 mRNA
CTD
PMID:26141394
NCBI chr 6:81,567,237...81,571,759
Ensembl chr 6:81,566,850...81,571,992
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Star
steroidogenic acute regulatory protein
decreases expression multiple interactions
EXP ISO
T-2 Toxin results in decreased expression of STAR mRNA; T-2 Toxin results in decreased expression of STAR protein 1-Methyl-3-isobutylxanthine inhibits the reaction [T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of STAR mRNA]]; T-2 Toxin inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of STAR mRNA]; T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of STAR mRNA] [T-2 Toxin co-treated with CGA protein] results in decreased activity of STAR protein; [T-2 Toxin co-treated with CGA protein] results in decreased expression of STAR mRNA
CTD
PMID:25542145 PMID:25962641 PMID:30951242
NCBI chr16:72,969,824...72,974,447
Ensembl chr16:72,961,518...72,974,447
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Stat1
signal transducer and activator of transcription 1
multiple interactions decreases expression increases phosphorylation increases expression
ISO EXP
alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in increased expression of STAT1 mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in increased phosphorylation of STAT1 protein]; stattic inhibits the reaction [T-2 Toxin results in increased expression of STAT1 mRNA]; stattic inhibits the reaction [T-2 Toxin results in increased phosphorylation of STAT1 protein] T-2 Toxin results in decreased expression of STAT1 mRNA
CTD
PMID:22454431 PMID:26141394
NCBI chr 9:56,911,522...56,951,926
Ensembl chr 9:56,911,523...57,077,346
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Stat2
signal transducer and activator of transcription 2
increases expression decreases expression
ISO EXP
T-2 Toxin results in increased expression of STAT2 mRNA T-2 Toxin results in decreased expression of STAT2 mRNA
CTD
PMID:22454431 PMID:26141394
NCBI chr 7:1,287,025...1,302,858
Ensembl chr 7:1,287,024...1,303,459
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Stat3
signal transducer and activator of transcription 3
multiple interactions decreases expression increases expression increases phosphorylation
ISO EXP
alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in increased expression of STAT3 mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in increased phosphorylation of STAT3 protein]; stattic inhibits the reaction [T-2 Toxin results in increased expression of STAT3 mRNA]; stattic inhibits the reaction [T-2 Toxin results in increased phosphorylation of STAT3 protein] T-2 Toxin results in decreased expression of STAT3 mRNA
CTD
PMID:22454431 PMID:26141394
NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359
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Stat5b
signal transducer and activator of transcription 5B
decreases expression
ISO
T-2 Toxin results in decreased expression of STAT5B mRNA
CTD
PMID:34581912
NCBI chr10:86,205,148...86,276,178
Ensembl chr10:86,207,293...86,275,990
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Stk4
serine/threonine kinase 4
decreases expression
EXP
T-2 Toxin results in decreased expression of STK4 mRNA
CTD
PMID:26141394
NCBI chr 3:152,745,958...152,827,747
Ensembl chr 3:173,165,083...173,247,134
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Stoml2
stomatin like 2
affects expression
EXP
T-2 Toxin affects the expression of STOML2 protein
CTD
PMID:26141394
NCBI chr 5:62,052,042...62,055,639
Ensembl chr 5:62,052,045...62,055,670
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Sucnr1
succinate receptor 1
decreases expression
EXP
T-2 Toxin results in decreased expression of SUCNR1 mRNA
CTD
PMID:26141394
NCBI chr 2:146,368,858...146,380,360
Ensembl chr 2:146,368,858...146,380,360
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Suox
sulfite oxidase
decreases expression
EXP
T-2 Toxin results in decreased expression of SUOX mRNA
CTD
PMID:26141394
NCBI chr 7:1,687,666...1,691,759
Ensembl chr 7:1,687,666...1,690,235
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Sybu
syntabulin
increases expression decreases expression
EXP ISO
T-2 Toxin results in increased expression of SYBU mRNA T-2 Toxin results in decreased expression of SYBU mRNA
CTD
PMID:26141394 PMID:31863870
NCBI chr 7:77,731,662...77,833,413
Ensembl chr 7:77,731,605...77,833,686
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Syt11
synaptotagmin 11
decreases expression
EXP
T-2 Toxin results in decreased expression of SYT11 mRNA
CTD
PMID:26141394
NCBI chr 2:176,503,845...176,530,354
Ensembl chr 2:176,503,845...176,529,775
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Syt17
synaptotagmin 17
decreases expression
EXP
T-2 Toxin results in decreased expression of SYT17 mRNA
CTD
PMID:26141394
NCBI chr 1:172,695,275...172,761,906
Ensembl chr 1:182,129,496...182,204,028
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Tac1
tachykinin, precursor 1
increases expression
ISO
T-2 Toxin results in increased expression of TAC1 protein
CTD
PMID:30336258
NCBI chr 4:36,645,344...36,653,548
Ensembl chr 4:36,645,571...36,653,546
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Taldo1
transaldolase 1
affects expression
EXP
T-2 Toxin affects the expression of TALDO1 protein
CTD
PMID:26141394
NCBI chr 1:205,923,196...205,933,526
Ensembl chr 1:205,923,165...205,933,535
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Tatdn1
TatD DNase domain containing 1
increases expression
ISO
T-2 Toxin results in increased expression of TATDN1 mRNA
CTD
PMID:31863870
NCBI chr 7:92,339,452...92,370,445
Ensembl chr 7:92,330,554...92,370,400
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Tbxa2r
thromboxane A2 receptor
decreases expression
ISO
T-2 Toxin results in decreased expression of TBXA2R mRNA
CTD
PMID:34581912
NCBI chr 7:9,034,077...9,041,489
Ensembl chr 7:9,034,108...9,038,905
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Tcp1
t-complex 1
affects expression increases expression
EXP ISO
T-2 Toxin affects the expression of TCP1 protein T-2 Toxin results in increased expression of TCP1 protein
CTD
PMID:26141394 PMID:34581912
NCBI chr 1:50,376,848...50,384,527
Ensembl chr 1:50,376,848...50,384,527
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Terc
telomerase RNA component
decreases expression
EXP
T-2 Toxin results in decreased expression of TERC mRNA
CTD
PMID:26141394
NCBI chr 2:114,744,148...114,744,535
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Tf
transferrin
decreases expression
ISO
T-2 Toxin results in decreased expression of TF mRNA
CTD
PMID:34581912
NCBI chr 8:112,668,667...112,695,376
Ensembl chr 8:112,647,642...112,695,400
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Tfam
transcription factor A, mitochondrial
multiple interactions decreases expression increases expression
ISO EXP
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [T-2 Toxin results in decreased expression of TFAM protein] GABPA promotes the reaction [T-2 Toxin results in increased expression of TFAM mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to TFAM] T-2 Toxin results in decreased expression of TFAM mRNA; T-2 Toxin results in decreased expression of TFAM protein NFE2L2 protein affects the reaction [T-2 Toxin results in decreased expression of TFAM mRNA]; NFE2L2 protein affects the reaction [T-2 Toxin results in decreased expression of TFAM protein]
CTD
PMID:27363784 PMID:29870751 PMID:35842139 PMID:36863559
NCBI chr20:17,355,373...17,367,422
Ensembl chr20:17,355,363...17,369,877
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Tfb1m
transcription factor B1, mitochondrial
affects expression increases expression multiple interactions
EXP
T-2 Toxin affects the expression of TFB1M mRNA T-2 Toxin results in increased expression of TFB1M mRNA GABPA promotes the reaction [T-2 Toxin results in increased expression of TFB1M mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to TFB1M]
CTD
PMID:29870751 PMID:36863559
NCBI chr 1:46,520,510...46,567,004
Ensembl chr 1:46,524,435...46,566,948
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Tfb2m
transcription factor B2, mitochondrial
affects expression increases expression multiple interactions
EXP
T-2 Toxin affects the expression of TFB2M mRNA T-2 Toxin results in increased expression of TFB2M mRNA GABPA promotes the reaction [T-2 Toxin results in increased expression of TFB2M mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to TFB2M]
CTD
PMID:29870751 PMID:36863559
NCBI chr13:93,810,859...93,828,678
Ensembl chr13:93,810,731...93,828,594
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Tfe3
transcription factor binding to IGHM enhancer 3
increases expression
ISO
T-2 Toxin results in increased expression of TFE3 mRNA
CTD
PMID:34581912
NCBI chr X:17,401,466...17,414,829
Ensembl chr X:17,401,466...17,414,685
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Tgfbr1
transforming growth factor, beta receptor 1
increases expression
EXP
T-2 Toxin results in increased expression of TGFBR1 protein
CTD
PMID:35213812
NCBI chr 5:66,449,348...66,506,371
Ensembl chr 5:66,449,293...66,527,260
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Tgfbr2
transforming growth factor, beta receptor 2
increases expression
EXP
T-2 Toxin results in increased expression of TGFBR2 protein
CTD
PMID:35213812
NCBI chr 8:124,672,677...124,761,741
Ensembl chr 8:124,674,986...124,761,469
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Tgfbr3
transforming growth factor beta receptor 3
increases expression
ISO
T-2 Toxin results in increased expression of TGFBR3 mRNA
CTD
PMID:34581912
NCBI chr14:2,634,294...2,810,269
Ensembl chr14:2,634,188...2,810,271
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Tgm2
transglutaminase 2
decreases expression
ISO
T-2 Toxin results in decreased expression of TGM2 mRNA
CTD
PMID:34581912
NCBI chr 3:167,192,612...167,221,845
Ensembl chr 3:167,192,612...167,304,240
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Thbs1
thrombospondin 1
decreases expression increases expression
ISO
T-2 Toxin results in decreased expression of THBS1 mRNA T-2 Toxin results in increased expression of THBS1 mRNA
CTD
PMID:31863870 PMID:34581912
NCBI chr 3:125,510,250...125,525,402
Ensembl chr 3:125,510,250...125,525,402
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Thbs2
thrombospondin 2
decreases expression
ISO
T-2 Toxin results in decreased expression of THBS2 mRNA
CTD
PMID:31863870
NCBI chr 1:55,670,394...55,699,789
Ensembl chr 1:64,343,523...64,372,918
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Thbs3
thrombospondin 3
decreases expression
ISO
T-2 Toxin results in decreased expression of THBS3 mRNA
CTD
PMID:31863870
NCBI chr 2:174,621,788...174,633,594
Ensembl chr 2:176,919,230...176,931,357
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Thrb
thyroid hormone receptor beta
multiple interactions
ISO
T-2 Toxin inhibits the reaction [Triiodothyronine results in increased activity of THRB protein]
CTD
PMID:31077750
NCBI chr15:10,115,954...10,465,231
Ensembl chr15:10,115,954...10,313,680
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Timm50
translocase of inner mitochondrial membrane 50
increases expression
ISO
T-2 Toxin results in increased expression of TIMM50 mRNA
CTD
PMID:31863870
NCBI chr 1:92,702,437...92,710,311
Ensembl chr 1:92,702,437...92,710,311
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Timp1
TIMP metallopeptidase inhibitor 1
decreases expression affects expression multiple interactions
ISO
T-2 Toxin results in decreased expression of TIMP1 protein T-2 Toxin affects the expression of TIMP1 mRNA Selenium inhibits the reaction [T-2 Toxin results in decreased expression of TIMP1 protein]
CTD
PMID:21112371 PMID:21144892
NCBI chr X:3,766,509...3,772,578
Ensembl chr X:3,766,510...3,771,135
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Timp2
TIMP metallopeptidase inhibitor 2
decreases expression affects expression multiple interactions
ISO
T-2 Toxin results in decreased expression of TIMP2 protein T-2 Toxin affects the expression of TIMP2 mRNA Selenium inhibits the reaction [T-2 Toxin results in decreased expression of TIMP2 protein]
CTD
PMID:21112371 PMID:21144892
NCBI chr10:104,041,604...104,089,214
Ensembl chr10:104,041,604...104,089,214
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Timp3
TIMP metallopeptidase inhibitor 3
decreases expression
ISO
T-2 Toxin results in decreased expression of TIMP3 mRNA
CTD
PMID:31863870
NCBI chr 7:19,408,539...19,459,558
Ensembl chr 7:19,409,631...19,459,547
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Tkt
transketolase
affects expression
EXP
T-2 Toxin affects the expression of TKT protein
CTD
PMID:26141394
NCBI chr16:5,729,381...5,755,170
Ensembl chr16:5,729,991...5,756,431
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Tmem102
transmembrane protein 102
decreases expression
EXP
T-2 Toxin results in decreased expression of TMEM102 mRNA
CTD
PMID:26141394
NCBI chr10:55,022,625...55,025,676
Ensembl chr10:55,021,303...55,024,668
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Tmem123
transmembrane protein 123
decreases expression
EXP
T-2 Toxin results in decreased expression of TMEM123 mRNA
CTD
PMID:26141394
NCBI chr 8:13,206,907...13,237,069
Ensembl chr 8:13,206,403...13,257,427
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Tmem167a
transmembrane protein 167A
decreases expression
ISO
T-2 Toxin results in decreased expression of TMEM167A mRNA
CTD
PMID:31863870
NCBI chr 2:22,933,027...22,951,974
Ensembl chr Y:3,291,213...3,291,891 Ensembl chr 2:3,291,213...3,291,891
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Tmem25
transmembrane protein 25
decreases expression
ISO
T-2 Toxin results in decreased expression of TMEM25 mRNA
CTD
PMID:31863870
NCBI chr 8:45,107,116...45,112,657
Ensembl chr 8:54,003,907...54,009,325
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Tmem50b
transmembrane protein 50B
decreases expression
ISO
T-2 Toxin results in decreased expression of TMEM50B mRNA
CTD
PMID:31863870
NCBI chr11:30,804,835...30,837,675
Ensembl chr11:44,290,807...44,323,607
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Tnf
tumor necrosis factor
multiple interactions decreases methylation increases expression
ISO EXP
Selenium promotes the reaction [T-2 Toxin results in increased expression of TNF protein] T-2 Toxin results in decreased methylation of TNF promoter Decitabine promotes the reaction [T-2 Toxin results in decreased methylation of TNF promoter]; Decitabine promotes the reaction [T-2 Toxin results in increased expression of TNF mRNA] T-2 Toxin results in increased expression of TNF mRNA; T-2 Toxin results in increased expression of TNF protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [T-2 Toxin results in increased expression of TNF mRNA]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [T-2 Toxin results in increased expression of TNF mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in increased expression of TNF mRNA]; ATG3 protein affects the reaction [T-2 Toxin results in increased expression of TNF mRNA]; BTG2 protein affects the reaction [T-2 Toxin results in increased expression of TNF mRNA]; Minocycline inhibits the reaction [T-2 Toxin results in increased expression of TNF mRNA]; MIR155 mRNA promotes the reaction [T-2 Toxin results in increased expression of TNF mRNA]; pyrazolanthrone inhibits the reaction [T-2 Toxin results in increased expression of TNFA mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [T-2 Toxin results in increased expression of TNF mRNA]; RHEB protein promotes the reaction [T-2 Toxin results in increased expression of TNF mRNA]; stattic inhibits the reaction [T-2 Toxin results in increased expression of TNF mRNA]
CTD
PMID:18196609 PMID:21112371 PMID:22454431 PMID:22960706 PMID:29079362 PMID:31170431 PMID:31279042 PMID:32240701 PMID:36775139 PMID:39147216 More...
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
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Tnfrsf12a
TNF receptor superfamily member 12A
increases expression
EXP ISO
T-2 Toxin results in increased expression of TNFRSF12A mRNA
CTD
PMID:26141394 PMID:34581912
NCBI chr10:13,211,670...13,213,666
Ensembl chr10:13,211,673...13,213,704
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Tnfrsf21
TNF receptor superfamily member 21
increases expression
ISO
T-2 Toxin results in increased expression of TNFRSF21 mRNA
CTD
PMID:34581912
NCBI chr 9:25,376,400...25,451,323
Ensembl chr 9:25,376,400...25,451,323
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Tomm34
translocase of outer mitochondrial membrane 34
increases expression
ISO
T-2 Toxin results in increased expression of TOMM34 mRNA
CTD
PMID:31863870
NCBI chr 3:173,148,737...173,165,689
Ensembl chr 3:173,145,279...173,165,814
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Top2a
DNA topoisomerase II alpha
decreases expression
ISO
T-2 Toxin results in decreased expression of TOP2A mRNA
CTD
PMID:34581912
NCBI chr10:84,441,954...84,473,093
Ensembl chr10:84,441,954...84,473,366
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Tp53
tumor protein p53
increases expression decreases expression
EXP ISO
T-2 Toxin results in increased expression of TP53 mRNA; T-2 Toxin results in increased expression of TP53 protein T-2 Toxin results in decreased expression of TP53 mRNA T-2 Toxin results in increased expression of TRP53 mRNA; T-2 Toxin results in increased expression of TRP53 protein
CTD
PMID:19524637 PMID:21296132 PMID:29432840 PMID:29567467 PMID:29870751 PMID:34581912 More...
NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
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Tpi1
triosephosphate isomerase 1
affects expression
EXP
T-2 Toxin affects the expression of TPI1 protein
CTD
PMID:26141394
NCBI chr 4:159,301,558...159,305,088
Ensembl chr 4:159,301,562...159,305,413
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Tpp1
tripeptidyl peptidase 1
decreases expression
ISO
T-2 Toxin results in decreased expression of TPP1 mRNA
CTD
PMID:31863870
NCBI chr 1:169,509,816...169,515,939
Ensembl chr 1:169,509,815...169,516,024
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Tpr
translocated promoter region, nuclear basket protein
decreases expression
ISO
T-2 Toxin results in decreased expression of TPR mRNA
CTD
PMID:34581912
NCBI chr13:64,974,419...65,037,604
Ensembl chr13:64,974,419...65,037,602
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Traf2
Tnf receptor-associated factor 2
increases expression
EXP
T-2 Toxin results in increased expression of TRAF2 mRNA
CTD
PMID:26141394
NCBI chr 3:28,740,098...28,764,752
Ensembl chr 3:28,740,098...28,764,691
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Trap1
TNF receptor-associated protein 1
affects expression
EXP
T-2 Toxin affects the expression of TRAP1 protein
CTD
PMID:26141394
NCBI chr10:11,971,259...12,005,306
Ensembl chr10:11,970,995...12,005,355
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Trib2
tribbles pseudokinase 2
decreases expression
ISO
T-2 Toxin results in decreased expression of TRIB2 mRNA
CTD
PMID:34581912
NCBI chr 6:38,545,971...38,570,349
Ensembl chr 6:44,274,762...44,299,094
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Trib3
tribbles pseudokinase 3
decreases expression
ISO
T-2 Toxin results in decreased expression of TRIB3 mRNA
CTD
PMID:31863870 PMID:34581912
NCBI chr 3:161,269,939...161,275,533
Ensembl chr 3:161,269,955...161,274,802
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Trmt1
tRNA methyltransferase 1
increases expression
ISO
T-2 Toxin results in increased expression of TRMT1 mRNA
CTD
PMID:34581912
NCBI chr19:23,456,756...23,471,581
Ensembl chr19:40,361,583...40,374,622
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Trmu
tRNA mitochondrial 2-thiouridylase
increases expression
ISO
T-2 Toxin results in increased expression of TRMU mRNA
CTD
PMID:34581912
NCBI chr 7:118,849,586...118,866,190
Ensembl chr 7:118,849,600...118,867,539
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Tsc22d1
TSC22 domain family, member 1
increases expression
ISO
T-2 Toxin results in increased expression of TSC22D1 mRNA
CTD
PMID:34581912
NCBI chr15:58,159,612...58,260,244
Ensembl chr15:58,159,952...58,183,322
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Tspan8
tetraspanin 8
decreases expression
ISO
T-2 Toxin results in decreased expression of TSPAN8 mRNA
CTD
PMID:31863870
NCBI chr 7:53,331,019...53,365,402
Ensembl chr 7:53,330,963...53,365,401
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Tsr2
TSR2, ribosome maturation factor
increases expression
ISO
T-2 Toxin results in increased expression of TSR2 mRNA
CTD
PMID:34581912
NCBI chr X:20,064,102...20,072,673
Ensembl chr X:23,507,142...23,515,659
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Ttc7a
tetratricopeptide repeat domain 7A
increases expression
ISO
T-2 Toxin results in increased expression of TTC7A mRNA
CTD
PMID:34581912
NCBI chr 6:7,159,285...7,261,826
Ensembl chr 6:12,905,527...13,015,374
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Ttk
Ttk protein kinase
decreases expression
ISO
T-2 Toxin results in decreased expression of TTK mRNA
CTD
PMID:34581912
NCBI chr 8:93,632,678...93,672,664
Ensembl chr 8:93,634,319...93,672,664
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Ttn
titin
decreases expression
ISO
T-2 Toxin results in decreased expression of TTN mRNA
CTD
PMID:34581912
NCBI chr 3:82,059,648...82,332,130
Ensembl chr 3:82,059,648...82,332,171
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Ttr
transthyretin
multiple interactions
ISO
T-2 Toxin inhibits the reaction [Thyroxine binds to TTR protein]
CTD
PMID:31077750
NCBI chr18:12,216,684...12,225,972
Ensembl chr18:12,216,732...12,225,969
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Tuba1c
tubulin, alpha 1C
affects expression
EXP
T-2 Toxin affects the expression of TUBA1C protein
CTD
PMID:26141394
NCBI chr 7:131,636,974...132,078,589
Ensembl chr 7:132,070,536...132,079,311
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Tubb5
tubulin, beta 5 class I
affects expression
EXP
T-2 Toxin affects the expression of TUBB protein
CTD
PMID:26141394
NCBI chr20:2,917,577...2,921,726
Ensembl chr20:2,917,539...2,921,726
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Tube1
tubulin, epsilon 1
decreases expression
ISO
T-2 Toxin results in decreased expression of TUBE1 mRNA
CTD
PMID:34581912
NCBI chr20:44,105,405...44,124,947
Ensembl chr20:44,107,022...44,125,271
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Tufm
Tu translation elongation factor, mitochondrial
affects expression
EXP
T-2 Toxin affects the expression of TUFM protein
CTD
PMID:26141394
NCBI chr 1:190,504,373...190,507,980
Ensembl chr 1:190,504,373...190,508,952
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Txnl4b
thioredoxin-like 4B
increases expression
ISO
T-2 Toxin results in increased expression of TXNL4B mRNA
CTD
PMID:34581912
NCBI chr19:54,439,686...54,449,777
Ensembl chr19:54,439,680...54,448,052
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Ube2n
ubiquitin-conjugating enzyme E2N
affects expression
EXP
T-2 Toxin affects the expression of UBE2N protein
CTD
PMID:26141394
NCBI chr 7:32,041,190...32,071,252
G
Uchl1
ubiquitin C-terminal hydrolase L1
affects expression
EXP
T-2 Toxin affects the expression of UCHL1 protein
CTD
PMID:26141394
NCBI chr14:41,838,859...41,849,743
Ensembl chr14:41,838,861...41,849,417
G
Ucp1
uncoupling protein 1
increases expression
EXP
T-2 Toxin results in increased expression of UCP1 mRNA
CTD
PMID:29870751
NCBI chr19:41,713,350...41,721,421
Ensembl chr19:41,713,351...41,721,420
G
Ucp2
uncoupling protein 2
increases expression
EXP
T-2 Toxin results in increased expression of UCP2 mRNA
CTD
PMID:29870751
NCBI chr 1:164,251,373...164,257,742
Ensembl chr 1:164,251,373...164,257,743
G
Ucp3
uncoupling protein 3
increases expression
EXP
T-2 Toxin results in increased expression of UCP3 mRNA
CTD
PMID:29870751
NCBI chr 1:164,227,910...164,240,893
Ensembl chr 1:164,227,882...164,241,210
G
Upf3a
UPF3A, regulator of nonsense mediated mRNA decay
increases expression
EXP
T-2 Toxin results in increased expression of UPF3A mRNA
CTD
PMID:26141394
NCBI chr16:75,757,442...75,768,478
Ensembl chr16:82,459,906...82,470,686
G
Uqcrfs1
ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
increases expression multiple interactions
EXP
T-2 Toxin results in increased expression of UQCRFS1 mRNA T-2 Toxin promotes the reaction [GABPA protein binds to UQCRFS1]
CTD
PMID:29870751 PMID:36863559
NCBI chr17:34,173,787...34,190,952
Ensembl chr17:34,173,833...34,190,950
G
Utp14a
UTP14A small subunit processome component
increases expression
ISO
T-2 Toxin results in increased expression of UTP14A mRNA
CTD
PMID:34581912
NCBI chr X:132,317,163...132,342,524
Ensembl chr X:132,317,159...132,342,523
G
Vat1
vesicle amine transport 1
increases expression
ISO
T-2 Toxin results in increased expression of VAT1 protein
CTD
PMID:34581912
NCBI chr10:86,889,793...86,897,411
Ensembl chr10:86,889,793...86,897,411
G
Vdac1
voltage-dependent anion channel 1
affects expression
EXP
T-2 Toxin affects the expression of VDAC1 protein
CTD
PMID:26141394
NCBI chr10:37,029,377...37,060,542
Ensembl chr10:37,023,145...37,060,541
G
Vdac2
voltage-dependent anion channel 2
increases expression
ISO
T-2 Toxin results in increased expression of VDAC2 protein
CTD
PMID:34581912
NCBI chr15:2,512,214...2,526,105
Ensembl chr15:2,512,216...2,532,229
G
Vegfa
vascular endothelial growth factor A
increases expression
ISO
T-2 Toxin results in increased expression of VEGFA protein
CTD
PMID:36115646
NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194
G
Veph1
ventricular zone expressed PH domain-containing 1
increases expression
ISO
T-2 Toxin results in increased expression of VEPH1 mRNA
CTD
PMID:31863870
NCBI chr 2:152,592,648...152,847,566
Ensembl chr 2:152,601,680...152,847,318
G
Vti1a
vesicle transport through interaction with t-SNAREs 1A
increases expression
EXP
T-2 Toxin results in increased expression of VTI1A mRNA
CTD
PMID:26141394
NCBI chr 1:264,361,538...264,667,171
Ensembl chr 1:264,361,522...264,668,727
G
Wars1
tryptophanyl-tRNA synthetase 1
decreases expression
ISO
T-2 Toxin results in decreased expression of WARS1 mRNA
CTD
PMID:31863870 PMID:34581912
NCBI chr 6:133,540,463...133,571,645
Ensembl chr 6:133,539,744...133,571,645
G
Wdr54
WD repeat domain 54
increases expression
ISO
T-2 Toxin results in increased expression of WDR54 mRNA
CTD
PMID:31863870
NCBI chr 4:115,654,968...115,677,979
Ensembl chr 4:117,212,677...117,219,270
G
Wdr74
WD repeat domain 74
increases expression
ISO
T-2 Toxin results in increased expression of WDR74 mRNA
CTD
PMID:31863870
NCBI chr 1:215,060,901...215,065,687
Ensembl chr 1:215,060,961...215,066,336
G
Wipi1
WD repeat domain, phosphoinositide interacting 1
decreases expression
ISO
T-2 Toxin results in decreased expression of WIPI1 mRNA
CTD
PMID:31863870
NCBI chr10:95,042,451...95,079,679
Ensembl chr10:95,042,441...95,079,293
G
Wnt3a
Wnt family member 3A
decreases expression multiple interactions
ISO
T-2 Toxin results in decreased expression of WNT3A protein 3-methyladenine promotes the reaction [T-2 Toxin results in decreased expression of WNT3A protein]
CTD
PMID:35289972 PMID:36402210
NCBI chr10:44,533,734...44,577,919
Ensembl chr10:44,533,734...44,577,919
G
Xbp1
X-box binding protein 1
increases expression decreases expression
ISO
T-2 Toxin results in increased expression of XBP1 protein alternative form T-2 Toxin results in decreased expression of XBP1 mRNA
CTD
PMID:31170431 PMID:31863870
NCBI chr14:84,604,623...84,609,707
Ensembl chr14:84,604,107...84,609,706
G
Yars2
tyrosyl-tRNA synthetase 2
multiple interactions
EXP
T-2 Toxin promotes the reaction [GABPA protein binds to YARS2]
CTD
PMID:36863559
NCBI chr11:98,136,530...98,142,320
Ensembl chr11:98,115,386...98,142,668
G
Ybx1
Y box binding protein 1
increases expression
ISO
T-2 Toxin results in increased expression of YBX1 protein
CTD
PMID:34581912
NCBI chr 5:138,167,444...138,188,155
Ensembl chr 5:138,167,444...138,184,188
G
Ywhab
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
affects expression
EXP
T-2 Toxin affects the expression of YWHAB protein
CTD
PMID:26141394
NCBI chr 3:173,078,904...173,101,508
Ensembl chr 3:173,079,041...173,101,854
G
Ywhae
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
affects expression
EXP
T-2 Toxin affects the expression of YWHAE protein
CTD
PMID:26141394
NCBI chr10:61,082,934...61,120,618
Ensembl chr10:61,106,716...61,114,291
G
Ywhag
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
affects expression
EXP
T-2 Toxin affects the expression of YWHAG protein
CTD
PMID:26141394
NCBI chr12:26,381,106...26,409,466
Ensembl chr12:26,380,816...26,409,465
G
Ywhaq
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
affects expression
EXP
T-2 Toxin affects the expression of YWHAQ protein
CTD
PMID:26141394
NCBI chr 6:46,664,358...46,694,875
Ensembl chr 6:46,664,358...46,694,875
G
Zbtb21
zinc finger and BTB domain containing 21
increases expression
ISO
T-2 Toxin results in increased expression of ZBTB21 mRNA
CTD
PMID:31863870
NCBI chr11:50,781,697...50,796,399
Ensembl chr11:50,781,099...50,796,560
G
Zbtb40
zinc finger and BTB domain containing 40
increases expression
ISO
T-2 Toxin results in increased expression of ZBTB40 mRNA
CTD
PMID:34581912
NCBI chr 5:149,216,496...149,283,746
Ensembl chr 5:154,503,128...154,537,863
G
Zc3h8
zinc finger CCCH type containing 8
increases expression
ISO
T-2 Toxin results in increased expression of ZC3H8 mRNA
CTD
PMID:31863870
NCBI chr 3:116,176,779...116,193,752
Ensembl chr 3:136,629,999...136,646,952
G
Zfp346
zinc finger protein 346
increases expression
ISO
T-2 Toxin results in increased expression of ZNF346 mRNA
CTD
PMID:34581912
NCBI chr17:9,493,787...9,523,681
Ensembl chr17:9,498,933...9,528,783
G
Zfp382
zinc finger protein 382
increases expression
ISO
T-2 Toxin results in increased expression of ZNF382 mRNA
CTD
PMID:34581912
NCBI chr 1:85,377,614...85,400,832
Ensembl chr 1:94,505,067...94,528,334
G
Zfp422
zinc finger protein 422
increases expression
ISO
T-2 Toxin results in increased expression of ZNF22 mRNA
CTD
PMID:31863870
NCBI chr 4:149,885,805...149,893,287
Ensembl chr 4:151,556,738...151,566,152
G
Zfp623
zinc finger protein 623
increases expression
ISO
T-2 Toxin results in increased expression of ZNF623 mRNA
CTD
PMID:34581912
NCBI chr 7:109,508,046...109,516,965
Ensembl chr 7:109,514,586...109,518,381
G
Il2
interleukin 2
increases expression affects secretion
ISO
muconomycin A results in increased expression of IL2 mRNA muconomycin A affects the secretion of IL2 protein
CTD
PMID:8560498
NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672
G
Il4
interleukin 4
affects secretion increases expression
ISO
muconomycin A affects the secretion of IL4 protein muconomycin A results in increased expression of IL4 mRNA
CTD
PMID:8560498
NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549
G
Il5
interleukin 5
affects secretion
ISO
muconomycin A affects the secretion of IL5 protein
CTD
PMID:8560498
NCBI chr10:38,375,132...38,378,003
Ensembl chr10:38,375,132...38,378,003
G
Il6
interleukin 6
increases expression
ISO
muconomycin A results in increased expression of IL6 mRNA
CTD
PMID:8560498
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all
Path 1
CHEBI ontology
20862
role
20820
biological role
20818
poison
19105
toxin
16258
mycotoxin
12277
trichothecene
1985
(1S,2S,12S)-3,11-dihydroxy-1,2,5-trimethylspiro[8-oxatricyclo[7.2.1.02,7]dodec-5-ene-12,2'-oxirane]-4-one
0
(2'E)-Roridin L-2
0
(3alpha)-3-Hydroxy-12,13-epoxytrichothec-9-ene-4,8,15-triyl triacetate
0
(S)-7-hydroxytrichothecolone acetate
0
12'-Hydroxyroridin E
0
13'-Acetyltrichoverrin B
0
14'-hydroxymytoxin B
0
14′-dehydrovertisporin
0
15-Acetoxyscirpene-3,4-diol 4-O-a-D-glucopyranoside
0
15-Acetoxyscirpenol
0
15-Acetyl-4-deoxynivalenol
0
15-Deacetylneosolaniol
0
15-acetyldeoxynivalenol
93
15-acetyltrichoverrol B
0
16-hydroxymytoxin B
0
16-hydroxyroridin E
0
2′,3′-deoxyroritoxin D
0
3'-Hydroxy-HT2 toxin
0
3'-Hydroxy-T2 Toxin
0
3'-Hydroxy-T2-triol
0
3,4,15-Trihydroxy-12,13-epoxytrichothec-9-en-8-yl 3-methylbutanoate
0
3,7,8,15-Scirpenetetrol
0
3,8,15-Trihydroxy-12,13-epoxytrichothec-9-en-4-yl acetate
0
3-Acetoxyscirpene-4,15-diol
0
3-Hydroxyroridin E
0
3-acetyldeoxynivalenol
33
3′-epi-16-hydroxyverrucarin A
0
3′-epiverrucarin X
0
4,8-Diacetyl-T2-tetrol
0
4-((Z)-but-2-enoyloxy)-12,13-epoxy-16-hydroxytrichothec-9-ene
0
4-Acetoxyscirpene-3,15-diol
0
4-Deacetylneosolaniol
0
4-Propanoyl-HT2 toxin
0
6'-dehydroxytrichoverrin B
0
6′,12′-epoxymyrotoxin A
0
7'-hydroxymytoxin B
0
7-Hydroxytrichodermol
0
7alpha,8alpha-Dihydroxycalonectrin
0
7beta,8,beta2,'3'-diepoxyroridin H
0
7beta,8beta-epoxyisororidin E
0
7beta,8beta-epoxyroridin H
0
8-Acetoxyroridin E
0
8-Acetoxyroridin H
0
8-Acetyl-T2 tetrol
0
8-Butanoylneosolaniol
0
8-Hexanoylneosolaniol
0
8-Isobutanoylneosolaniol
0
8-Oxodiacetoxyscirpenol
0
8-Pentanoylneosolaniol
0
8-Propanoylneosolaniol
0
8-acetoxy T-2 tetraol
0
8-acetylneosolaniol
0
8-n-Hexanoylneosolaniol
0
8-n-Pentanoylneosolaniol
0
8a-Hydroxyisotrichoverrin A
0
9beta,10beta-Epoxyisotrichoverrin A
0
Acetyl-T2 Toxin
0
Acetyldeoxynivalenol
0
Acetyltrichothecolone
0
Anguidine
0
Anguidol
0
Chartarene D
0
Crotocin
0
DON-10-S-cysteine
0
DON-10-gamma-glutamylcysteine
0
DON-10-glutathione
0
DON-10-isoleucine
0
DON-10-leucine
0
DON-10-phenylalanine
0
DON-10-tyrosine
0
DON-13-S-cysteine
0
DON-15-penicillin G
0
DON-15-sulfate
0
DON-3-sulfate
0
DON-sulfonate 1
0
DON-sulfonate 2
0
DON-sulfonate 3
0
Deoxynivalenol 3-glucoside
2
Diacetoxyscirpenol
21
Epiroridin acid
0
Fusarenone X
43
HT-2 toxin +
815
Harzianum A
0
Isororidin E
0
Isororidin P
0
LSM-36622
0
Monoacetoxyscirpenol
0
Myotoxin A
0
Myrotoxin A
0
Myrotoxin B
0
NX-2
0
NX-3
0
NX-4
0
Neosolaniol
2
Nivalenol
246
Pentahydroxyscirpene
0
Roridin A
12
Roridin E
0
Roridin E acetate
0
Roridin F
0
Roridin H
0
Roridin J
0
Roridin K acetate
0
Roridin L
0
Roridin M
0
Roridin P
0
Roridin Q
0
Roridin R
0
Roridoxin A
0
Roridoxin B
0
Roridoxin C
0
Roritoxin A
0
Roritoxin B
0
Roritoxin C
0
Roritoxin D
0
Satratoxin H
3
Satratoxin H 12',13'-diacetate
0
Satratoxin H 12'-acetate
0
Satratoxin H 13'-acetate
0
Satratoxin I
0
Sporotrichiol
0
Stachybotrichodermone A
0
Standard Solution Nivalenol
0
T-2 Tetraol
0
T-2 toxin
809
T2 Toxin Triol
0
T2 Triol
0
Toxin T2 tetrol
0
Trichobreol A
0
Trichobreol B
0
Trichobreol C
0
Trichodermadiene
0
Trichodermadienediol A
0
Trichodermadienediol B
0
Trichodermarin C
0
Trichodermarin D
0
Trichodermarin E
0
Trichothecinol A
0
Trichothecinol B
0
Trichothecinol C
0
Trichoverrin A
0
Trichoverrin B
0
Trichoverrin C
0
Trichoverritone
0
Trichoverrol A
0
Trichoverrol B
0
Verrol
0
Verrol 4-acetate
0
Verrucarin L
0
Verrucarin L acetate
0
Verrucarin M
0
Verrucarin X
0
Verrucarin Y
0
Verrucarin Z
0
Verrucarin j
0
Verrucarol
0
YM-47524
0
YM-47525
0
[(1R,2R,4S,7R,9R,10R,12S)-2-(acetyloxymethyl)-10-hydroxy-1,5-dimethylspiro[8-oxatricyclo[7.2.1.02,7]dodec-5-ene-12,2'-oxirane]-4-yl] 3-methylbutanoate
0
[(1S,2R,4S,7R,9R,10R,11S,12R)-11-acetyloxy-2-(acetyloxymethyl)-10-hydroxy-1,5-dimethylspiro[8-oxatricyclo[7.2.1.02,7]dodec-5-ene-12,2'-oxirane]-4-yl] 3-methylbutanoate
0
deoxynivalenol +
1331
isotrichodermol
0
trichothecin
0
verrucarin A
4
Path 2
CHEBI ontology
20862
subatomic particle
20860
composite particle
20860
hadron
20860
baryon
20860
nucleon
20860
atomic nucleus
20860
atom
20860
main group element atom
20781
p-block element atom
20781
carbon group element atom
20715
carbon atom
20710
organic molecular entity
20710
organic molecule
20654
organic cyclic compound
20404
organic heterocyclic compound
19388
organic heteromonocyclic compound
18212
saturated organic heteromonocyclic parent
11505
oxirane
11487
epoxide
11486
trichothecene
1985
(1S,2S,12S)-3,11-dihydroxy-1,2,5-trimethylspiro[8-oxatricyclo[7.2.1.02,7]dodec-5-ene-12,2'-oxirane]-4-one
0
(2'E)-Roridin L-2
0
(3alpha)-3-Hydroxy-12,13-epoxytrichothec-9-ene-4,8,15-triyl triacetate
0
(S)-7-hydroxytrichothecolone acetate
0
12'-Hydroxyroridin E
0
13'-Acetyltrichoverrin B
0
14'-hydroxymytoxin B
0
14′-dehydrovertisporin
0
15-Acetoxyscirpene-3,4-diol 4-O-a-D-glucopyranoside
0
15-Acetoxyscirpenol
0
15-Acetyl-4-deoxynivalenol
0
15-Deacetylneosolaniol
0
15-acetyldeoxynivalenol
93
15-acetyltrichoverrol B
0
16-hydroxymytoxin B
0
16-hydroxyroridin E
0
2′,3′-deoxyroritoxin D
0
3'-Hydroxy-HT2 toxin
0
3'-Hydroxy-T2 Toxin
0
3'-Hydroxy-T2-triol
0
3,4,15-Trihydroxy-12,13-epoxytrichothec-9-en-8-yl 3-methylbutanoate
0
3,7,8,15-Scirpenetetrol
0
3,8,15-Trihydroxy-12,13-epoxytrichothec-9-en-4-yl acetate
0
3-Acetoxyscirpene-4,15-diol
0
3-Hydroxyroridin E
0
3-acetyldeoxynivalenol
33
3′-epi-16-hydroxyverrucarin A
0
3′-epiverrucarin X
0
4,8-Diacetyl-T2-tetrol
0
4-((Z)-but-2-enoyloxy)-12,13-epoxy-16-hydroxytrichothec-9-ene
0
4-Acetoxyscirpene-3,15-diol
0
4-Deacetylneosolaniol
0
4-Propanoyl-HT2 toxin
0
6'-dehydroxytrichoverrin B
0
6′,12′-epoxymyrotoxin A
0
7'-hydroxymytoxin B
0
7-Hydroxytrichodermol
0
7alpha,8alpha-Dihydroxycalonectrin
0
7beta,8,beta2,'3'-diepoxyroridin H
0
7beta,8beta-epoxyisororidin E
0
7beta,8beta-epoxyroridin H
0
8-Acetoxyroridin E
0
8-Acetoxyroridin H
0
8-Acetyl-T2 tetrol
0
8-Butanoylneosolaniol
0
8-Hexanoylneosolaniol
0
8-Isobutanoylneosolaniol
0
8-Oxodiacetoxyscirpenol
0
8-Pentanoylneosolaniol
0
8-Propanoylneosolaniol
0
8-acetoxy T-2 tetraol
0
8-acetylneosolaniol
0
8-n-Hexanoylneosolaniol
0
8-n-Pentanoylneosolaniol
0
8a-Hydroxyisotrichoverrin A
0
9beta,10beta-Epoxyisotrichoverrin A
0
Acetyl-T2 Toxin
0
Acetyldeoxynivalenol
0
Acetyltrichothecolone
0
Anguidine
0
Anguidol
0
Chartarene D
0
Crotocin
0
DON-10-S-cysteine
0
DON-10-gamma-glutamylcysteine
0
DON-10-glutathione
0
DON-10-isoleucine
0
DON-10-leucine
0
DON-10-phenylalanine
0
DON-10-tyrosine
0
DON-13-S-cysteine
0
DON-15-penicillin G
0
DON-15-sulfate
0
DON-3-sulfate
0
DON-sulfonate 1
0
DON-sulfonate 2
0
DON-sulfonate 3
0
Deoxynivalenol 3-glucoside
2
Diacetoxyscirpenol
21
Epiroridin acid
0
Fusarenone X
43
HT-2 toxin +
815
Harzianum A
0
Isororidin E
0
Isororidin P
0
LSM-36622
0
Monoacetoxyscirpenol
0
Myotoxin A
0
Myrotoxin A
0
Myrotoxin B
0
NX-2
0
NX-3
0
NX-4
0
Neosolaniol
2
Nivalenol
246
Pentahydroxyscirpene
0
Roridin A
12
Roridin E
0
Roridin E acetate
0
Roridin F
0
Roridin H
0
Roridin J
0
Roridin K acetate
0
Roridin L
0
Roridin M
0
Roridin P
0
Roridin Q
0
Roridin R
0
Roridoxin A
0
Roridoxin B
0
Roridoxin C
0
Roritoxin A
0
Roritoxin B
0
Roritoxin C
0
Roritoxin D
0
Satratoxin H
3
Satratoxin H 12',13'-diacetate
0
Satratoxin H 12'-acetate
0
Satratoxin H 13'-acetate
0
Satratoxin I
0
Sporotrichiol
0
Stachybotrichodermone A
0
Standard Solution Nivalenol
0
T-2 Tetraol
0
T-2 toxin
809
T2 Toxin Triol
0
T2 Triol
0
Toxin T2 tetrol
0
Trichobreol A
0
Trichobreol B
0
Trichobreol C
0
Trichodermadiene
0
Trichodermadienediol A
0
Trichodermadienediol B
0
Trichodermarin C
0
Trichodermarin D
0
Trichodermarin E
0
Trichothecinol A
0
Trichothecinol B
0
Trichothecinol C
0
Trichoverrin A
0
Trichoverrin B
0
Trichoverrin C
0
Trichoverritone
0
Trichoverrol A
0
Trichoverrol B
0
Verrol
0
Verrol 4-acetate
0
Verrucarin L
0
Verrucarin L acetate
0
Verrucarin M
0
Verrucarin X
0
Verrucarin Y
0
Verrucarin Z
0
Verrucarin j
0
Verrucarol
0
YM-47524
0
YM-47525
0
[(1R,2R,4S,7R,9R,10R,12S)-2-(acetyloxymethyl)-10-hydroxy-1,5-dimethylspiro[8-oxatricyclo[7.2.1.02,7]dodec-5-ene-12,2'-oxirane]-4-yl] 3-methylbutanoate
0
[(1S,2R,4S,7R,9R,10R,11S,12R)-11-acetyloxy-2-(acetyloxymethyl)-10-hydroxy-1,5-dimethylspiro[8-oxatricyclo[7.2.1.02,7]dodec-5-ene-12,2'-oxirane]-4-yl] 3-methylbutanoate
0
deoxynivalenol +
1331
isotrichodermol
0
trichothecin
0
verrucarin A
4