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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:ifosfamides
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Accession:CHEBI:55369 term browser browse the term
Definition:Compounds containing an ifosfamide skeleton.
Synonyms:related_synonym: isosfamides


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ifosfamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression
multiple interactions
ISO Ifosfamide results in increased expression of ABCB1 protein
[Ifosfamide results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA; NR1I2 protein promotes the reaction [Ifosfamide results in increased expression of ABCB1 protein]
CTD PMID:20041327 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcb6 ATP binding cassette subfamily B member 6 increases expression ISO Ifosfamide results in increased expression of ABCB6 mRNA CTD PMID:25596134 NCBI chr 9:82,373,950...82,382,228
Ensembl chr 9:82,373,946...82,382,272
JBrowse link
G Abcb9 ATP binding cassette subfamily B member 9 increases expression ISO Ifosfamide results in increased expression of ABCB9 mRNA CTD PMID:25596134 NCBI chr12:37,923,974...37,956,678
Ensembl chr12:37,923,528...37,958,363
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 decreases expression ISO Ifosfamide results in decreased expression of ABCG1 mRNA CTD PMID:25596134 NCBI chr20:9,743,269...9,842,735
Ensembl chr20:9,743,269...9,840,489
JBrowse link
G Abhd4 abhydrolase domain containing 4, N-acyl phospholipase B increases expression ISO Ifosfamide results in increased expression of ABHD4 mRNA CTD PMID:25596134 NCBI chr15:32,888,233...32,906,861
Ensembl chr15:32,894,938...32,906,850
JBrowse link
G Ache acetylcholinesterase increases activity
multiple interactions
EXP Ifosfamide results in increased activity of ACHE protein
morin inhibits the reaction [Ifosfamide results in increased activity of ACHE protein]
CTD PMID:31722249 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 decreases expression ISO Ifosfamide results in decreased expression of ACSL1 mRNA CTD PMID:25596134 NCBI chr16:48,937,456...49,003,898
Ensembl chr16:48,937,456...49,003,246
JBrowse link
G Agrn agrin increases expression ISO Ifosfamide results in increased expression of AGRN mRNA CTD PMID:25596134 NCBI chr 5:173,589,910...173,622,813
Ensembl chr 5:173,589,819...173,622,645
JBrowse link
G Ahr aryl hydrocarbon receptor affects activity ISO Ifosfamide affects the activity of AHR protein CTD PMID:25596134 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Ak4 adenylate kinase 4 increases expression ISO Ifosfamide results in increased expression of AK4 mRNA CTD PMID:25596134 NCBI chr 5:120,250,318...120,309,153
Ensembl chr 5:120,250,616...120,305,897
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 increases expression ISO Ifosfamide results in increased expression of AKR1C2 mRNA CTD PMID:25596134 NCBI chr17:69,388,337...69,435,160
Ensembl chr17:69,388,335...69,404,341
JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 increases expression ISO Ifosfamide results in increased expression of ALDH1A3 mRNA CTD PMID:25596134 NCBI chr 1:127,302,920...127,337,828
Ensembl chr 1:127,301,128...127,337,882
JBrowse link
G Aldoa aldolase, fructose-bisphosphate A increases expression ISO Ifosfamide results in increased expression of ALDOA mRNA CTD PMID:25596134 NCBI chr 1:198,228,387...198,233,988
Ensembl chr 1:198,228,387...198,233,588
JBrowse link
G Als2cl ALS2 C-terminal like affects expression ISO Ifosfamide affects the expression of ALS2CL mRNA CTD PMID:25596134 NCBI chr 8:119,156,081...119,176,680
Ensembl chr 8:119,160,731...119,174,830
JBrowse link
G Ankra2 ankyrin repeat family A member 2 decreases expression ISO Ifosfamide results in decreased expression of ANKRA2 mRNA CTD PMID:25596134 NCBI chr  X:82,407,601...82,418,229
Ensembl chr  X:82,407,598...82,418,425
JBrowse link
G Arhgef10 Rho guanine nucleotide exchange factor 10 affects expression ISO Ifosfamide affects the expression of ARHGEF10 mRNA CTD PMID:25596134 NCBI chr16:79,725,629...79,817,065
Ensembl chr16:79,725,643...79,793,619
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression ISO Ifosfamide results in increased expression of ASNS mRNA CTD PMID:25596134 NCBI chr 4:33,742,876...33,761,106
Ensembl chr 4:33,743,364...33,761,163
JBrowse link
G Atf4 activating transcription factor 4 affects activity ISO Ifosfamide affects the activity of ATF4 protein CTD PMID:25596134 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Atxn1 ataxin 1 decreases expression ISO Ifosfamide results in decreased expression of ATXN1 mRNA CTD PMID:25596134 NCBI chr17:19,160,986...19,533,814
Ensembl chr17:19,249,952...19,533,814
JBrowse link
G Aurkb aurora kinase B increases expression ISO Ifosfamide results in increased expression of AURKB mRNA CTD PMID:25596134 NCBI chr10:55,625,860...55,632,399
Ensembl chr10:55,626,741...55,634,991
JBrowse link
G Avp arginine vasopressin multiple interactions ISO [Ifosfamide co-treated with Mesna] results in increased expression of AVP protein CTD PMID:2261371 NCBI chr 3:123,117,482...123,119,460
Ensembl chr 3:123,117,492...123,119,460
JBrowse link
G Axl Axl receptor tyrosine kinase increases expression ISO Ifosfamide results in increased expression of AXL mRNA CTD PMID:25596134 NCBI chr 1:82,550,892...82,580,761
Ensembl chr 1:82,549,420...82,580,761
JBrowse link
G B2m beta-2 microglobulin increases expression ISO Ifosfamide results in increased expression of B2M protein CTD PMID:8625085, PMID:9261752 NCBI chr 3:114,087,287...114,093,311
Ensembl chr 3:114,087,287...114,093,309
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO Ifosfamide results in increased expression of BAX mRNA CTD PMID:25596134 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcat1 branched chain amino acid transaminase 1 decreases expression ISO Ifosfamide results in decreased expression of BCAT1 mRNA CTD PMID:25596134 NCBI chr 4:179,259,305...179,340,021
Ensembl chr 4:179,259,308...179,339,795
JBrowse link
G Bche butyrylcholinesterase increases activity
multiple interactions
EXP Ifosfamide results in increased activity of BCHE protein
morin inhibits the reaction [Ifosfamide results in increased activity of BCHE protein]
CTD PMID:31722249 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
ISO
EXP
BCL2 protein inhibits the reaction [Ifosfamide results in increased activity of CASP9 protein]
Carnitine inhibits the reaction [Ifosfamide results in decreased expression of BCL2 mRNA]; morin inhibits the reaction [Ifosfamide results in decreased expression of BCL2 mRNA]
CTD PMID:11723234, PMID:23213347, PMID:31722249 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions
increases expression
EXP morin inhibits the reaction [Ifosfamide results in increased expression of BDNF mRNA] CTD PMID:31722249 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Bglap bone gamma-carboxyglutamate protein decreases expression ISO Ifosfamide results in decreased expression of BGLAP protein CTD PMID:1525342 NCBI chr 2:187,741,770...187,748,445
Ensembl chr 2:187,741,770...187,742,747
JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 increases expression ISO Ifosfamide results in increased expression of BHLHE40 mRNA CTD PMID:25596134 NCBI chr 4:140,703,619...140,709,319
Ensembl chr 4:140,703,619...140,709,319
JBrowse link
G Bnip3 BCL2 interacting protein 3 decreases expression ISO Ifosfamide results in decreased expression of BNIP3 mRNA CTD PMID:25596134 NCBI chr 1:211,248,098...211,265,282
Ensembl chr 1:211,248,098...211,265,282
JBrowse link
G Brd2 bromodomain containing 2 decreases expression ISO Ifosfamide results in decreased expression of BRD2 mRNA CTD PMID:25596134 NCBI chr20:3,910,555...3,921,074
Ensembl chr20:3,910,555...3,917,426
Ensembl chr20:3,910,555...3,917,426
JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO Ifosfamide results in increased expression of BTG2 mRNA CTD PMID:25596134 NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982
JBrowse link
G Camkk2 calcium/calmodulin-dependent protein kinase kinase 2 increases expression ISO Ifosfamide results in increased expression of CAMKK2 mRNA CTD PMID:25596134 NCBI chr12:39,253,409...39,302,601
Ensembl chr12:39,253,409...39,302,601
JBrowse link
G Cars cysteinyl-tRNA synthetase decreases expression ISO Ifosfamide results in decreased expression of CARS1 mRNA CTD PMID:25596134 NCBI chr 1:216,759,367...216,801,652
Ensembl chr 1:216,759,366...216,801,656
JBrowse link
G Casp1 caspase 1 increases response to substance ISO CASP1 results in increased susceptibility to Ifosfamide CTD PMID:9491796 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
increases expression
EXP Carnitine inhibits the reaction [Ifosfamide results in increased expression of CASP3 mRNA]; morin inhibits the reaction [Ifosfamide results in increased activity of CASP3 protein] CTD PMID:23213347, PMID:31722249 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp9 caspase 9 multiple interactions
increases expression
ISO
EXP
BCL2 protein inhibits the reaction [Ifosfamide results in increased activity of CASP9 protein]
Carnitine inhibits the reaction [Ifosfamide results in increased expression of CASP9 mRNA]
CTD PMID:11723234, PMID:23213347 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase multiple interactions
decreases activity
decreases expression
EXP Carnitine inhibits the reaction [Ifosfamide results in decreased expression of CAT mRNA]; morin inhibits the reaction [Ifosfamide results in decreased activity of CAT protein] CTD PMID:23213347, PMID:31722249 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccdc90b coiled-coil domain containing 90B decreases expression ISO Ifosfamide results in decreased expression of CCDC90B mRNA CTD PMID:25596134 NCBI chr 1:157,403,595...157,417,153
Ensembl chr 1:157,403,595...157,417,147
JBrowse link
G Ccne2 cyclin E2 increases expression ISO Ifosfamide results in increased expression of CCNE2 mRNA CTD PMID:25596134 NCBI chr 5:24,434,077...24,446,406
Ensembl chr 5:24,434,872...24,446,406
JBrowse link
G Ccng2 cyclin G2 decreases expression ISO Ifosfamide results in decreased expression of CCNG2 mRNA CTD PMID:25596134 NCBI chr14:16,267,572...16,276,068
Ensembl chr14:16,267,573...16,276,068
JBrowse link
G Cda cytidine deaminase multiple interactions EXP [CYP2B1 co-treated with CDA] results in increased susceptibility to [Ifosfamide co-treated with Fluorouracil]; [CYP2B1 co-treated with CDA] results in increased susceptibility to Ifosfamide CTD PMID:10811482 NCBI chr 5:156,703,579...156,734,541
Ensembl chr 5:156,703,579...156,734,541
JBrowse link
G Cdk6 cyclin-dependent kinase 6 affects expression ISO Ifosfamide affects the expression of CDK6 mRNA CTD PMID:25596134 NCBI chr 4:27,781,728...27,969,653
Ensembl chr 4:27,785,647...27,966,398
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO Ifosfamide results in increased expression of CDKN1A mRNA CTD PMID:25596134 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cers5 ceramide synthase 5 increases expression ISO Ifosfamide results in increased expression of CERS5 mRNA CTD PMID:25596134 NCBI chr 7:141,386,391...141,424,375
Ensembl chr 7:141,386,391...141,424,343
JBrowse link
G Cmbl carboxymethylenebutenolidase homolog increases expression ISO Ifosfamide results in increased expression of CMBL mRNA CTD PMID:25596134 NCBI chr 2:84,645,084...84,666,836
Ensembl chr 2:84,645,084...84,666,835
JBrowse link
G Ctdp1 CTD phosphatase subunit 1 decreases expression ISO Ifosfamide results in decreased expression of CTDP1 mRNA CTD PMID:25596134 NCBI chr18:76,922,913...76,985,095
Ensembl chr18:76,922,934...76,984,203
JBrowse link
G Cth cystathionine gamma-lyase affects expression ISO Ifosfamide affects the expression of CTH mRNA CTD PMID:25596134 NCBI chr 2:264,266,959...264,293,040
Ensembl chr 2:264,266,984...264,293,046
JBrowse link
G Ctsc cathepsin C increases expression ISO Ifosfamide results in increased expression of CTSC mRNA CTD PMID:25596134 NCBI chr 1:151,918,514...151,949,979
Ensembl chr 1:151,918,571...151,949,983
JBrowse link
G Cttn cortactin increases expression ISO Ifosfamide results in increased expression of CTTN mRNA CTD PMID:25596134 NCBI chr 1:217,602,698...217,638,196
NCBI chr 1:215,255,385...215,290,882
Ensembl chr 1:217,602,698...217,638,152
Ensembl chr 1:217,602,698...217,638,152
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases response to substance
decreases expression
ISO CYP1A1 protein results in increased susceptibility to Ifosfamide
Ifosfamide results in decreased expression of CYP1A1 mRNA
CTD PMID:20507880, PMID:25596134 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression ISO Ifosfamide results in increased expression of CYP1A2 mRNA CTD PMID:25596134 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases expression ISO Ifosfamide results in decreased expression of CYP1B1 mRNA CTD PMID:25596134 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions
increases response to substance
increases activity
increases metabolic processing
increases hydroxylation
EXP [CYP2B1 co-treated with CDA] results in increased susceptibility to [Ifosfamide co-treated with Fluorouracil]; [CYP2B1 co-treated with CDA] results in increased susceptibility to Ifosfamide; Metyrapone inhibits the reaction [CYP2B1 results in increased susceptibility to Ifosfamide]; Mitomycin affects the reaction [CYP2B1 results in increased susceptibility to Ifosfamide]
CYP2B1 results in increased activity of Ifosfamide
CYP2B1 protein results in increased metabolism of Ifosfamide; CYP2B1 results in increased metabolism of Ifosfamide
CYP2B1 protein mutant form results in increased hydroxylation of Ifosfamide
CTD PMID:2272335, PMID:7834628, PMID:8640822, PMID:9592392, PMID:10415877, PMID:10811482, PMID:15102956 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases response to substance
affects metabolic processing
multiple interactions
ISO CYP2B6 results in increased susceptibility to Ifosfamide
CYP2B6 protein affects the metabolism of Ifosfamide
POR promotes the reaction [CYP2B6 results in increased susceptibility to Ifosfamide]
CTD PMID:9766669, PMID:15875221 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp2c24 cytochrome P450, family 2, subfamily c, polypeptide 24 increases metabolic processing
increases response to substance
increases activity
multiple interactions
ISO CYP2C18 results in increased metabolism of Ifosfamide
CYP2C18 results in increased susceptibility to Ifosfamide
CYP2C18 results in increased activity of Ifosfamide
POR promotes the reaction [CYP2C18 results in increased susceptibility to Ifosfamide]
CTD PMID:9241661, PMID:9766669, PMID:15301741 NCBI chr 1:258,074,797...258,139,176
Ensembl chr 1:258,074,860...258,139,176
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 increases response to substance
increases activity
ISO CYP2C19 protein results in increased susceptibility to Ifosfamide
CYP2C19 results in increased activity of Ifosfamide
CTD PMID:9241661, PMID:20507880 NCBI chr 1:147,713,879...147,814,410
Ensembl chr 1:147,713,892...147,888,007
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 increases activity ISO CYP2C8 results in increased activity of Ifosfamide CTD PMID:9241661 NCBI chr 1:147,236,480...147,307,988 JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 increases response to substance ISO CYP2D6 protein results in increased susceptibility to Ifosfamide CTD PMID:20507880 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases hydroxylation EXP CYP3A23-3A1 protein results in increased hydroxylation of Ifosfamide CTD PMID:15919850 NCBI chr12:11,053,888...11,082,742
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 affects metabolic processing
decreases ethylation
ISO CYP3A5 protein affects the metabolism of Ifosfamide
CYP3A5 protein results in decreased ethylation of Ifosfamide
CTD PMID:15821045, PMID:15875221 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO Ifosfamide results in increased expression of DDIT3 mRNA CTD PMID:25596134 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression ISO Ifosfamide results in increased expression of DDIT4 mRNA CTD PMID:25596134 NCBI chr20:29,509,283...29,511,382
Ensembl chr20:29,509,289...29,511,382
JBrowse link
G Ddx17 DEAD-box helicase 17 decreases expression ISO Ifosfamide results in decreased expression of DDX17 mRNA CTD PMID:25596134 NCBI chr 7:120,761,843...120,765,012
Ensembl chr 7:120,761,826...120,780,641
JBrowse link
G Dgka diacylglycerol kinase, alpha increases expression ISO Ifosfamide results in increased expression of DGKA mRNA CTD PMID:25596134 NCBI chr 7:3,143,826...3,170,764
Ensembl chr 7:3,143,827...3,170,146
JBrowse link
G Dlx1 distal-less homeobox 1 decreases expression ISO Ifosfamide results in decreased expression of DLX1 mRNA CTD PMID:25596134 NCBI chr 3:58,164,931...58,169,521
Ensembl chr 3:58,164,931...58,169,521
JBrowse link
G Dnai3 dynein axonemal intermediate chain 3 decreases expression ISO Ifosfamide results in decreased expression of DNAI3 mRNA CTD PMID:25596134 NCBI chr 2:251,912,432...251,970,699
Ensembl chr 2:251,912,368...251,970,768
JBrowse link
G Dnajb2 DnaJ heat shock protein family (Hsp40) member B2 increases expression ISO Ifosfamide results in increased expression of DNAJB2 mRNA CTD PMID:25596134 NCBI chr 9:82,436,453...82,444,669
Ensembl chr 9:82,436,458...82,444,668
JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 increases expression ISO Ifosfamide results in increased expression of DNAJB9 mRNA CTD PMID:25596134 NCBI chr 6:64,165,913...64,170,122
Ensembl chr 6:64,165,913...64,170,151
JBrowse link
G Dnmbp dynamin binding protein increases expression ISO Ifosfamide results in increased expression of DNMBP mRNA CTD PMID:25596134 NCBI chr 1:263,625,503...263,718,784
Ensembl chr 1:263,625,501...263,718,745
JBrowse link
G Dpm3 dolichyl-phosphate mannosyltransferase subunit 3, regulatory increases expression ISO Ifosfamide results in increased expression of DPM3 mRNA CTD PMID:25596134 NCBI chr 2:188,583,664...188,584,179
Ensembl chr 2:188,583,664...188,584,179
JBrowse link
G Dusp22 dual specificity phosphatase 22 increases expression ISO Ifosfamide results in increased expression of DUSP22 mRNA CTD PMID:25596134 NCBI chr17:34,986,589...35,037,297
Ensembl chr17:34,986,591...35,037,076
JBrowse link
G Efna1 ephrin A1 decreases expression ISO Ifosfamide results in decreased expression of EFNA1 mRNA CTD PMID:25596134 NCBI chr 2:188,588,808...188,596,156
Ensembl chr 2:188,588,796...188,596,222
JBrowse link
G Eif1 eukaryotic translation initiation factor 1 increases expression ISO Ifosfamide results in increased expression of EIF1 mRNA CTD PMID:25596134 NCBI chr10:88,227,455...88,229,546
Ensembl chr10:88,227,360...88,229,765
JBrowse link
G Eif3c eukaryotic translation initiation factor 3, subunit C decreases expression ISO Ifosfamide results in decreased expression of EIF3C mRNA CTD PMID:25596134 NCBI chr 1:197,964,406...197,982,917
Ensembl chr 1:197,964,407...197,982,601
JBrowse link
G Elf4 E74 like ETS transcription factor 4 increases expression ISO Ifosfamide results in increased expression of ELF4 mRNA CTD PMID:25596134 NCBI chr  X:135,239,626...135,284,330
Ensembl chr  X:135,240,451...135,250,519
JBrowse link
G Elk4 ETS transcription factor ELK4 decreases expression ISO Ifosfamide results in decreased expression of ELK4 mRNA CTD PMID:25596134 NCBI chr13:48,788,262...48,813,267
Ensembl chr13:48,790,509...48,813,260
JBrowse link
G Eno2 enolase 2 increases expression ISO Ifosfamide results in increased expression of ENO2 mRNA CTD PMID:25596134 NCBI chr 4:157,285,192...157,294,090
Ensembl chr 4:157,285,179...157,294,047
JBrowse link
G Ep400 E1A binding protein p400 decreases expression ISO Ifosfamide results in decreased expression of EP400 mRNA CTD PMID:25596134 NCBI chr12:51,948,650...52,055,274
Ensembl chr12:51,948,650...52,055,271
JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha increases expression ISO Ifosfamide results in increased expression of ERO1A mRNA CTD PMID:25596134 NCBI chr15:19,619,947...19,655,381
Ensembl chr15:19,619,973...19,655,381
JBrowse link
G Exoc7 exocyst complex component 7 increases expression ISO Ifosfamide results in increased expression of EXOC7 mRNA CTD PMID:25596134 NCBI chr10:105,242,152...105,259,795
Ensembl chr10:105,242,152...105,259,795
JBrowse link
G Fabp3 fatty acid binding protein 3 decreases expression ISO Ifosfamide results in decreased expression of FABP3 mRNA CTD PMID:25596134 NCBI chr 5:148,528,854...148,535,597
Ensembl chr 5:148,528,725...148,535,565
JBrowse link
G Fam162a family with sequence similarity 162, member A decreases expression ISO Ifosfamide results in decreased expression of FAM162A mRNA CTD PMID:25596134 NCBI chr11:67,618,683...67,646,253
Ensembl chr11:67,618,625...67,646,253
JBrowse link
G Fam210b family with sequence similarity 210, member B decreases expression ISO Ifosfamide results in decreased expression of FAM210B mRNA CTD PMID:25596134 NCBI chr 3:170,354,109...170,364,265
Ensembl chr 3:170,354,141...170,362,513
JBrowse link
G Fam214a family with sequence similarity 214, member A decreases expression ISO Ifosfamide results in decreased expression of FAM214A mRNA CTD PMID:25596134 NCBI chr 8:81,863,619...81,941,548
Ensembl chr 8:81,863,619...81,941,536
JBrowse link
G Fam89a family with sequence similarity 89, member A increases expression ISO Ifosfamide results in increased expression of FAM89A mRNA CTD PMID:25596134 NCBI chr19:57,502,308...57,514,896
Ensembl chr19:57,502,308...57,514,896
JBrowse link
G Faslg Fas ligand increases expression ISO Ifosfamide results in increased expression of FASL CTD PMID:16453328 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fbxo22 F-box protein 22 increases expression ISO Ifosfamide results in increased expression of FBXO22 mRNA CTD PMID:25596134 NCBI chr 8:59,770,032...59,786,061
Ensembl chr 8:59,769,994...59,786,065
JBrowse link
G Fbxo30 F-box protein 30 decreases expression ISO Ifosfamide results in decreased expression of FBXO30 mRNA CTD PMID:25596134 NCBI chr 1:5,366,119...5,389,774
Ensembl chr 1:5,366,379...5,388,069
JBrowse link
G Fech ferrochelatase decreases expression ISO Ifosfamide results in decreased expression of FECH mRNA CTD PMID:25596134 NCBI chr18:59,941,992...59,975,192
Ensembl chr18:59,941,992...59,975,192
JBrowse link
G Flvcr2 FLVCR heme transporter 2 decreases expression ISO Ifosfamide results in decreased expression of FLVCR2 mRNA CTD PMID:25596134 NCBI chr 6:109,617,348...109,681,495
Ensembl chr 6:109,617,355...109,681,495
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
EXP morin inhibits the reaction [Ifosfamide results in increased expression of FOS protein] CTD PMID:31722249 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression ISO Ifosfamide results in increased expression of FOSL1 mRNA CTD PMID:25596134 NCBI chr 1:220,826,560...220,835,066
Ensembl chr 1:220,826,560...220,835,066
JBrowse link
G Gars glycyl-tRNA synthetase increases expression ISO Ifosfamide results in increased expression of GARS1 mRNA CTD PMID:25596134 NCBI chr 4:85,235,122...85,276,085
Ensembl chr 4:85,235,172...85,276,044
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit decreases expression ISO Ifosfamide results in decreased expression of GCLC mRNA CTD PMID:25596134 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Ifosfamide results in increased expression of GCLM mRNA CTD PMID:25596134 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO Ifosfamide results in increased expression of GDF15 mRNA CTD PMID:25596134 NCBI chr16:20,555,395...20,557,978
Ensembl chr16:20,555,395...20,557,978
JBrowse link
G Gfap glial fibrillary acidic protein increases expression
multiple interactions
EXP Ifosfamide results in increased expression of GFAP protein
morin inhibits the reaction [Ifosfamide results in increased expression of GFAP protein]
CTD PMID:31722249 NCBI chr10:90,990,762...90,999,435
Ensembl chr10:90,990,762...90,999,506
JBrowse link
G Gpat3 glycerol-3-phosphate acyltransferase 3 increases expression ISO Ifosfamide results in increased expression of GPAT3 mRNA CTD PMID:25596134 NCBI chr14:10,343,287...10,396,565
Ensembl chr14:10,343,282...10,395,047
JBrowse link
G Gpr87 G protein-coupled receptor 87 decreases expression ISO Ifosfamide results in decreased expression of GPR87 mRNA CTD PMID:25596134 NCBI chr 2:149,398,949...149,418,041
Ensembl chr 2:149,398,949...149,417,212
JBrowse link
G Gpr88 G-protein coupled receptor 88 increases expression ISO Ifosfamide results in increased expression of GPR88 mRNA CTD PMID:25596134 NCBI chr 2:219,258,346...219,263,819
Ensembl chr 2:219,258,347...219,262,901
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions
decreases expression
EXP Carnitine inhibits the reaction [Ifosfamide results in decreased expression of GPX1 mRNA] CTD PMID:23213347 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gpx3 glutathione peroxidase 3 decreases activity ISO Ifosfamide results in decreased activity of GPX3 protein CTD PMID:9851889 NCBI chr10:40,247,436...40,255,423
Ensembl chr10:40,247,436...40,255,422
JBrowse link
G Gsr glutathione-disulfide reductase increases expression ISO Ifosfamide results in increased expression of GSR mRNA CTD PMID:25596134 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gstp1 glutathione S-transferase pi 1 affects response to substance
increases response to substance
ISO GSTP1 gene polymorphism affects the susceptibility to Ifosfamide
GSTP1 gene polymorphism results in increased susceptibility to Ifosfamide
CTD PMID:12868187, PMID:16282887 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Herc3 HECT and RLD domain containing E3 ubiquitin protein ligase 3 decreases expression ISO Ifosfamide results in decreased expression of HERC3 mRNA CTD PMID:25596134 NCBI chr 4:89,078,670...89,169,150
Ensembl chr 4:89,078,711...89,169,146
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha affects activity ISO Ifosfamide affects the activity of HIF1A protein CTD PMID:25596134 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B increases expression ISO Ifosfamide results in increased expression of HSPA1B mRNA CTD PMID:25596134 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
JBrowse link
G Iars1 isoleucyl-tRNA synthetase 1 increases expression ISO Ifosfamide results in increased expression of IARS1 mRNA CTD PMID:25596134 NCBI chr17:15,356,016...15,402,680
Ensembl chr17:15,355,529...15,402,649
JBrowse link
G Ids iduronate 2-sulfatase decreases expression ISO Ifosfamide results in decreased expression of IDS mRNA CTD PMID:25596134 NCBI chr 8:69,447,971...69,466,708
Ensembl chr 8:69,449,801...69,466,618
JBrowse link
G Ifnb1 interferon beta 1 multiple interactions ISO [Ifosfamide co-treated with IFNB1] affects the expression of MMP9 mRNA; [Ifosfamide co-treated with IFNB1] affects the expression of MMP9 protein; [Ifosfamide co-treated with IFNB1] results in decreased expression of PLAUR protein; IFNB1 promotes the reaction [Ifosfamide results in decreased activity of MMP9 protein]; IFNB1 promotes the reaction [Ifosfamide results in decreased expression of VEGFA protein] CTD PMID:15659795 NCBI chr 5:106,865,192...106,865,746
Ensembl chr 5:106,865,192...106,865,746
JBrowse link
G Igf2r insulin-like growth factor 2 receptor increases expression ISO Ifosfamide results in increased expression of IGF2R mRNA CTD PMID:25596134 NCBI chr 1:48,176,095...48,264,482
Ensembl chr 1:48,176,106...48,264,477
JBrowse link
G Il19 interleukin 19 increases secretion ISO Ifosfamide results in increased secretion of IL19 protein CTD PMID:24714768 NCBI chr13:47,663,592...47,677,869
Ensembl chr13:47,664,080...47,670,407
JBrowse link
G Il1b interleukin 1 beta increases secretion
multiple interactions
EXP Ifosfamide results in increased secretion of IL1B protein
resveratrol inhibits the reaction [Ifosfamide results in increased secretion of IL1B protein]
CTD PMID:17481685 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 increases secretion
multiple interactions
EXP Ifosfamide results in increased secretion of IL6 protein
resveratrol inhibits the reaction [Ifosfamide results in increased secretion of IL6 protein]
CTD PMID:17481685 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Inka2 inka box actin regulator 2 increases expression ISO Ifosfamide results in increased expression of INKA2 mRNA CTD PMID:25596134 NCBI chr 2:208,170,652...208,187,088
Ensembl chr 2:208,170,652...208,185,965
JBrowse link
G Insig2 insulin induced gene 2 increases expression ISO Ifosfamide results in increased expression of INSIG2 mRNA CTD PMID:25596134 NCBI chr13:37,264,818...37,292,718
Ensembl chr13:37,266,312...37,287,458
JBrowse link
G Itfg2 integrin alpha FG-GAP repeat containing 2 decreases expression ISO Ifosfamide results in decreased expression of ITFG2 mRNA CTD PMID:25596134 NCBI chr 4:161,730,643...161,744,281
Ensembl chr 4:161,730,641...161,743,896
JBrowse link
G Itgb1 integrin subunit beta 1 affects expression ISO Ifosfamide affects the expression of ITGB1 mRNA CTD PMID:25596134 NCBI chr19:61,677,512...61,725,537
Ensembl chr19:61,677,542...61,725,535
JBrowse link
G Kat6b lysine acetyltransferase 6B decreases expression ISO Ifosfamide results in decreased expression of KAT6B mRNA CTD PMID:25596134 NCBI chr15:2,811,933...2,966,833
Ensembl chr15:2,813,537...2,966,576
JBrowse link
G Kdm3a lysine demethylase 3A decreases expression ISO Ifosfamide results in decreased expression of KDM3A mRNA CTD PMID:25596134 NCBI chr 4:99,503,160...99,547,315
Ensembl chr 4:99,503,176...99,546,905
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 increases expression ISO Ifosfamide results in increased expression of KEAP1 mRNA CTD PMID:25596134 NCBI chr 8:22,250,518...22,259,868
Ensembl chr 8:22,250,518...22,259,779
JBrowse link
G Krt15 keratin 15 increases expression ISO Ifosfamide results in increased expression of KRT15 mRNA CTD PMID:25596134 NCBI chr10:88,046,803...88,050,622
Ensembl chr10:88,046,803...88,050,622
JBrowse link
G Krt19 keratin 19 increases expression ISO Ifosfamide results in increased expression of KRT19 mRNA CTD PMID:25596134 NCBI chr10:88,055,843...88,060,560
Ensembl chr10:88,055,841...88,060,561
JBrowse link
G Lama3 laminin subunit alpha 3 increases expression ISO Ifosfamide results in increased expression of LAMA3 mRNA CTD PMID:25596134 NCBI chr18:3,704,866...3,941,215
Ensembl chr18:3,705,916...3,940,838
JBrowse link
G Lmcd1 LIM and cysteine-rich domains 1 decreases expression ISO Ifosfamide results in decreased expression of LMCD1 mRNA CTD PMID:25596134 NCBI chr 4:144,192,989...144,252,554
Ensembl chr 4:144,192,989...144,252,551
JBrowse link
G LOC100364500 RT1 class I, locus CE11-like affects expression ISO Ifosfamide affects the expression of HLA-A mRNA CTD PMID:25811541 NCBI chr20:2,704,153...2,707,111
Ensembl chr20:2,704,148...2,707,120
JBrowse link
G LOC691807 hypothetical protein LOC691807 decreases expression ISO Ifosfamide results in decreased expression of C4ORF3 mRNA CTD PMID:25596134 NCBI chr 2:227,095,487...227,097,247
Ensembl chr 2:227,095,487...227,097,246
JBrowse link
G Ltn1 listerin E3 ubiquitin protein ligase 1 decreases expression ISO Ifosfamide results in decreased expression of LTN1 mRNA CTD PMID:25596134 NCBI chr11:27,023,328...27,080,575
Ensembl chr11:27,022,986...27,080,701
JBrowse link
G Mafg MAF bZIP transcription factor G increases expression ISO Ifosfamide results in increased expression of MAFG mRNA CTD PMID:25596134 NCBI chr10:109,802,877...109,811,476
Ensembl chr10:109,806,159...109,811,323
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases activity
multiple interactions
EXP Ifosfamide results in increased activity of MAPK8 protein
morin inhibits the reaction [Ifosfamide results in increased activity of MAPK8 protein]
CTD PMID:31722249 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression ISO Ifosfamide results in increased expression of MDM2 mRNA CTD PMID:25596134 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Me1 malic enzyme 1 decreases expression ISO Ifosfamide results in decreased expression of ME1 mRNA CTD PMID:25596134 NCBI chr 8:94,256,830...94,368,834
Ensembl chr 8:94,256,839...94,368,834
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
decreases activity
affects expression
ISO [Ifosfamide co-treated with IFNA2] affects the expression of MMP9 mRNA; [Ifosfamide co-treated with IFNA2] affects the expression of MMP9 protein; [Ifosfamide co-treated with IFNB1] affects the expression of MMP9 mRNA; [Ifosfamide co-treated with IFNB1] affects the expression of MMP9 protein; IFNA2 promotes the reaction [Ifosfamide results in decreased activity of MMP9 protein]; IFNB1 promotes the reaction [Ifosfamide results in decreased activity of MMP9 protein]
Ifosfamide affects the expression of MMP9 mRNA
CTD PMID:15659795 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mr1 major histocompatibility complex, class I-related affects expression ISO Ifosfamide affects the expression of MR1 mRNA CTD PMID:25811541 NCBI chr13:72,771,992...72,789,861
Ensembl chr13:72,771,984...72,789,841
JBrowse link
G Mt2A metallothionein 2A increases expression ISO Ifosfamide results in increased expression of MT2A mRNA CTD PMID:25596134 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Mtdh metadherin decreases expression ISO Ifosfamide results in decreased expression of MTDH mRNA CTD PMID:25596134 NCBI chr 7:72,771,018...72,830,599
Ensembl chr 7:72,772,440...72,827,908
JBrowse link
G Mtfp1 mitochondrial fission process 1 increases expression ISO Ifosfamide results in increased expression of MTFP1 mRNA CTD PMID:25596134 NCBI chr14:84,330,223...84,334,063
Ensembl chr14:84,330,218...84,334,066
JBrowse link
G Mxi1 MAX interactor 1, dimerization protein decreases expression ISO Ifosfamide results in decreased expression of MXI1 mRNA CTD PMID:25596134 NCBI chr 1:274,030,748...274,090,071
Ensembl chr 1:274,030,978...274,090,071
JBrowse link
G Ncapd2 non-SMC condensin I complex, subunit D2 increases expression ISO Ifosfamide results in increased expression of NCAPD2 mRNA CTD PMID:25596134 NCBI chr 4:157,682,855...157,705,903
Ensembl chr 4:157,683,077...157,704,596
JBrowse link
G Nedd9 neural precursor cell expressed, developmentally down-regulated 9 decreases expression ISO Ifosfamide results in decreased expression of NEDD9 mRNA CTD PMID:25596134 NCBI chr17:22,984,792...23,179,701
Ensembl chr17:22,984,844...23,179,701
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 affects activity
decreases expression
multiple interactions
ISO
EXP
Ifosfamide affects the activity of NFE2L2 protein
Ifosfamide results in decreased expression of NFE2L2 protein
morin inhibits the reaction [Ifosfamide results in decreased expression of NFE2L2 protein]
CTD PMID:25596134, PMID:31722249 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nin ninein decreases expression ISO Ifosfamide results in decreased expression of NIN mRNA CTD PMID:25596134 NCBI chr 6:92,423,412...92,527,776
Ensembl chr 6:92,433,381...92,527,711
JBrowse link
G Nos1 nitric oxide synthase 1 increases activity
multiple interactions
EXP Ifosfamide results in increased activity of NOS1 protein
morin inhibits the reaction [Ifosfamide results in increased activity of NOS1 protein]
CTD PMID:31722249 NCBI chr12:44,214,949...44,405,530
Ensembl chr12:44,213,943...44,520,341
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
increases expression
EXP Carnitine inhibits the reaction [Ifosfamide results in increased expression of NOS2 mRNA] CTD PMID:23213347 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Npy1r neuropeptide Y receptor Y1 increases expression ISO Ifosfamide results in increased expression of NPY1R mRNA CTD PMID:25596134 NCBI chr16:24,779,480...24,789,131
Ensembl chr16:24,779,477...24,788,740
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 decreases expression ISO Ifosfamide results in decreased expression of NQO1 mRNA CTD PMID:25596134 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions
increases activity
ISO [Ifosfamide results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA; Ifosfamide binds to and results in increased activity of NR1I2 protein; NR1I2 protein promotes the reaction [Ifosfamide results in increased expression of ABCB1 protein] CTD PMID:18839173, PMID:20041327 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nrep neuronal regeneration related protein affects expression ISO Ifosfamide affects the expression of NREP mRNA CTD PMID:25596134 NCBI chr18:26,183,753...26,212,796
Ensembl chr18:26,185,259...26,211,445
JBrowse link
G Ntpcr nucleoside-triphosphatase, cancer-related increases expression ISO Ifosfamide results in increased expression of NTPCR mRNA CTD PMID:25596134 NCBI chr19:58,565,576...58,579,276
Ensembl chr19:58,565,576...58,579,265
JBrowse link
G Nuak1 NUAK family kinase 1 decreases expression ISO Ifosfamide results in decreased expression of NUAK1 mRNA CTD PMID:25596134 NCBI chr 7:25,039,336...25,111,118
Ensembl chr 7:25,039,335...25,113,664
JBrowse link
G Osgin1 oxidative stress induced growth inhibitor 1 decreases expression ISO Ifosfamide results in decreased expression of OSGIN1 mRNA CTD PMID:25596134 NCBI chr19:52,056,808...52,085,491
Ensembl chr19:52,077,109...52,085,496
JBrowse link
G P4ha1 prolyl 4-hydroxylase subunit alpha 1 decreases expression ISO Ifosfamide results in decreased expression of P4HA1 mRNA CTD PMID:25596134 NCBI chr20:28,920,616...28,972,576
Ensembl chr20:28,920,616...28,971,966
JBrowse link
G Pank1 pantothenate kinase 1 decreases expression ISO Ifosfamide results in decreased expression of PANK1 mRNA CTD PMID:25596134 NCBI chr 1:253,115,400...253,189,643
Ensembl chr 1:253,119,112...253,185,533
JBrowse link
G Pde8a phosphodiesterase 8A decreases expression ISO Ifosfamide results in decreased expression of PDE8A mRNA CTD PMID:25596134 NCBI chr 1:143,036,083...143,160,395
Ensembl chr 1:143,036,218...143,159,433
JBrowse link
G Pdia5 protein disulfide isomerase family A, member 5 increases expression ISO Ifosfamide results in increased expression of PDIA5 mRNA CTD PMID:25596134 NCBI chr11:68,493,035...68,578,999
Ensembl chr11:68,493,035...68,578,995
JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 decreases expression ISO Ifosfamide results in decreased expression of PDK1 mRNA CTD PMID:25596134 NCBI chr 3:58,530,870...58,561,494
Ensembl chr 3:58,530,870...58,558,027
JBrowse link
G Phgdh phosphoglycerate dehydrogenase increases expression ISO Ifosfamide results in increased expression of PHGDH mRNA CTD PMID:25596134 NCBI chr 2:200,484,245...200,513,564
Ensembl chr 2:200,484,246...200,513,564
JBrowse link
G Phlda3 pleckstrin homology-like domain, family A, member 3 increases expression ISO Ifosfamide results in increased expression of PHLDA3 mRNA CTD PMID:25596134 NCBI chr13:52,588,917...52,592,002
Ensembl chr13:52,588,917...52,592,001
JBrowse link
G Pidd1 p53-induced death domain protein 1 decreases expression ISO Ifosfamide results in decreased expression of PIDD1 mRNA CTD PMID:25596134 NCBI chr 1:214,418,751...214,423,959
Ensembl chr 1:214,419,240...214,423,881
JBrowse link
G Plaur plasminogen activator, urokinase receptor affects expression
multiple interactions
ISO Ifosfamide affects the expression of PLAUR protein
[Ifosfamide co-treated with IFNA2] results in decreased expression of PLAUR protein; [Ifosfamide co-treated with IFNB1] results in decreased expression of PLAUR protein
CTD PMID:15659795 NCBI chr 1:81,328,171...81,344,954
Ensembl chr 1:81,328,183...81,344,708
JBrowse link
G Pmepa1 prostate transmembrane protein, androgen induced 1 increases expression ISO Ifosfamide results in increased expression of PMEPA1 mRNA CTD PMID:25596134 NCBI chr 3:171,295,630...171,342,662
Ensembl chr 3:171,294,856...171,342,646
JBrowse link
G Podxl podocalyxin-like decreases expression ISO Ifosfamide results in decreased expression of PODXL mRNA CTD PMID:25596134 NCBI chr 4:58,829,049...58,893,353
Ensembl chr 4:58,829,060...58,893,170
JBrowse link
G Por cytochrome p450 oxidoreductase multiple interactions ISO POR promotes the reaction [CYP2B6 results in increased susceptibility to Ifosfamide]; POR promotes the reaction [CYP2C18 results in increased susceptibility to Ifosfamide] CTD PMID:9766669 NCBI chr12:23,998,411...24,017,063
Ensembl chr12:23,998,411...24,046,814
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects activity ISO Ifosfamide affects the activity of PPARG protein CTD PMID:25596134 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ppfibp1 PPFIA binding protein 1 increases expression ISO Ifosfamide results in increased expression of PPFIBP1 mRNA CTD PMID:25596134 NCBI chr 4:181,285,179...181,428,157
Ensembl chr 4:181,286,455...181,428,157
JBrowse link
G Ppig peptidylprolyl isomerase G decreases expression ISO Ifosfamide results in decreased expression of PPIG mRNA CTD PMID:25596134 NCBI chr 3:55,959,756...55,990,040
Ensembl chr 3:55,960,067...55,988,968
JBrowse link
G Ppm1d protein phosphatase, Mg2+/Mn2+ dependent, 1D decreases expression ISO Ifosfamide results in decreased expression of PPM1D mRNA CTD PMID:25596134 NCBI chr10:72,909,550...72,945,884
Ensembl chr10:72,909,550...72,945,884
JBrowse link
G Prc1 protein regulator of cytokinesis 1 increases expression ISO Ifosfamide results in increased expression of PRC1 mRNA CTD PMID:25596134 NCBI chr 1:142,087,181...142,108,746
Ensembl chr 1:142,087,208...142,108,746
JBrowse link
G Prdm1 PR/SET domain 1 decreases expression ISO Ifosfamide results in decreased expression of PRDM1 mRNA CTD PMID:25596134 NCBI chr20:49,464,921...49,556,623
Ensembl chr20:49,464,919...49,556,518
JBrowse link
G Prkab1 protein kinase AMP-activated non-catalytic subunit beta 1 affects expression ISO Ifosfamide affects the expression of PRKAB1 mRNA CTD PMID:25596134 NCBI chr12:46,316,298...46,326,789
Ensembl chr12:46,316,236...46,326,790
JBrowse link
G Prkab2 protein kinase AMP-activated non-catalytic subunit beta 2 affects expression ISO Ifosfamide affects the expression of PRKAB2 mRNA CTD PMID:25596134 NCBI chr 2:199,831,990...199,847,623
Ensembl chr 2:199,831,990...199,847,629
JBrowse link
G Psat1 phosphoserine aminotransferase 1 increases expression ISO Ifosfamide results in increased expression of PSAT1 mRNA CTD PMID:25596134 NCBI chr 1:233,124,089...233,145,941
Ensembl chr 1:233,124,092...233,145,941
JBrowse link
G Pspc1 paraspeckle component 1 decreases expression ISO Ifosfamide results in decreased expression of PSPC1 mRNA CTD PMID:25596134 NCBI chr15:36,946,914...37,030,273
Ensembl chr15:36,950,257...37,030,281
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
EXP etoricoxib inhibits the reaction [Ifosfamide results in increased expression of PTGS2 protein]; Indomethacin inhibits the reaction [Ifosfamide results in increased expression of PTGS2 protein]; Pentoxifylline inhibits the reaction [Ifosfamide results in increased expression of PTGS2 protein]; Thalidomide inhibits the reaction [Ifosfamide results in increased expression of PTGS2 protein] CTD PMID:17638016 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Pycr1 pyrroline-5-carboxylate reductase 1 increases expression ISO Ifosfamide results in increased expression of PYCR1 mRNA CTD PMID:25596134 NCBI chr10:109,817,300...109,822,218
Ensembl chr10:109,818,177...109,821,807
JBrowse link
G Pygl glycogen phosphorylase L decreases expression ISO Ifosfamide results in decreased expression of PYGL mRNA CTD PMID:25596134 NCBI chr 6:92,597,759...92,643,734
Ensembl chr 6:92,597,706...92,643,847
JBrowse link
G Rab31 RAB31, member RAS oncogene family increases expression ISO Ifosfamide results in increased expression of RAB31 mRNA CTD PMID:25596134 NCBI chr 9:113,370,072...113,504,606
Ensembl chr 9:113,370,033...113,504,605
JBrowse link
G Rffl ring finger and FYVE-like domain containing E3 ubiquitin protein ligase increases expression ISO Ifosfamide results in increased expression of RFFL mRNA CTD PMID:25596134 NCBI chr10:70,157,621...70,220,618
Ensembl chr10:70,157,621...70,220,582
JBrowse link
G RGD1308117 similar to 9930012K11Rik protein increases expression ISO Ifosfamide results in increased expression of C8ORF58 mRNA CTD PMID:25596134 NCBI chr15:51,834,703...51,841,412
Ensembl chr15:51,834,703...51,839,341
JBrowse link
G Rit1 Ras-like without CAAX 1 increases expression ISO Ifosfamide results in increased expression of RIT1 mRNA CTD PMID:25596134 NCBI chr 2:188,087,486...188,099,444
Ensembl chr 2:188,087,486...188,099,444
JBrowse link
G Rlf RLF zinc finger increases expression ISO Ifosfamide results in increased expression of RLF mRNA CTD PMID:25596134 NCBI chr 5:140,107,144...140,162,698
Ensembl chr 5:140,107,275...140,162,642
JBrowse link
G Rnf121 ring finger protein 121 decreases expression ISO Ifosfamide results in decreased expression of RNF121 mRNA CTD PMID:25596134 NCBI chr 1:167,095,916...167,165,257
Ensembl chr 1:167,095,962...167,165,265
JBrowse link
G Ro60 Ro60, Y RNA binding protein decreases expression ISO Ifosfamide results in decreased expression of RO60 mRNA CTD PMID:25596134 NCBI chr13:60,546,892...60,567,882
Ensembl chr13:60,546,912...60,567,882
JBrowse link
G Rps27l ribosomal protein S27-like increases expression ISO Ifosfamide results in increased expression of RPS27L mRNA CTD PMID:25596134 NCBI chr 8:72,741,155...72,746,090
Ensembl chr 8:72,741,155...72,746,090
JBrowse link
G Rrm2b ribonucleotide reductase regulatory TP53 inducible subunit M2B decreases expression ISO Ifosfamide results in decreased expression of RRM2B mRNA CTD PMID:25596134 NCBI chr 7:76,750,045...76,780,817
Ensembl chr 7:76,750,050...76,780,817
JBrowse link
G Rrp12 ribosomal RNA processing 12 homolog increases expression ISO Ifosfamide results in increased expression of RRP12 mRNA CTD PMID:25596134 NCBI chr 1:261,106,768...261,140,416
Ensembl chr 1:261,106,760...261,140,389
JBrowse link
G Rsrc2 arginine and serine rich coiled-coil 2 decreases expression ISO Ifosfamide results in decreased expression of RSRC2 mRNA CTD PMID:25596134 NCBI chr12:38,274,290...38,294,294
Ensembl chr12:38,274,297...38,294,292
JBrowse link
G Sars1 seryl-tRNA synthetase 1 increases expression ISO Ifosfamide results in increased expression of SARS1 mRNA CTD PMID:25596134 NCBI chr 2:211,219,743...211,235,475
Ensembl chr 2:211,219,750...211,235,467
JBrowse link
G Sertad1 SERTA domain containing 1 increases expression ISO Ifosfamide results in increased expression of SERTAD1 mRNA CTD PMID:25596134 NCBI chr 1:84,293,102...84,296,370
Ensembl chr 1:84,293,102...84,296,367
JBrowse link
G Sesn1 sestrin 1 increases expression ISO Ifosfamide results in increased expression of SESN1 mRNA CTD PMID:25596134 NCBI chr20:46,667,116...46,758,306
Ensembl chr20:46,667,121...46,758,305
JBrowse link
G Sfn stratifin increases expression ISO Ifosfamide results in increased expression of SFN mRNA CTD PMID:25596134 NCBI chr 5:151,823,422...151,824,937
Ensembl chr 5:151,823,887...151,824,633
JBrowse link
G Sh3tc1 SH3 domain and tetratricopeptide repeats 1 decreases expression ISO Ifosfamide results in decreased expression of SH3TC1 mRNA CTD PMID:25596134 NCBI chr14:80,184,814...80,229,207
Ensembl chr14:80,195,715...80,229,214
JBrowse link
G Siah2 siah E3 ubiquitin protein ligase 2 increases expression ISO Ifosfamide results in increased expression of SIAH2 mRNA CTD PMID:25596134 NCBI chr 2:148,874,151...148,891,900
Ensembl chr 2:148,874,151...148,891,900
JBrowse link
G Sipa1l2 signal-induced proliferation-associated 1 like 2 decreases expression ISO Ifosfamide results in decreased expression of SIPA1L2 mRNA CTD PMID:25596134 NCBI chr19:58,236,201...58,399,842
Ensembl chr19:58,236,214...58,399,816
JBrowse link
G Siva1 SIVA1, apoptosis-inducing factor increases expression ISO Ifosfamide results in increased expression of SIVA1 mRNA CTD PMID:25596134 NCBI chr 6:137,209,999...137,214,379
Ensembl chr 6:137,210,052...137,214,388
JBrowse link
G Slc12a8 solute carrier family 12, member 8 decreases expression ISO Ifosfamide results in decreased expression of SLC12A8 mRNA CTD PMID:25596134 NCBI chr11:70,344,771...70,499,202
Ensembl chr11:70,344,797...70,499,200
JBrowse link
G Slc1a5 solute carrier family 1 member 5 increases expression ISO Ifosfamide results in increased expression of SLC1A5 mRNA CTD PMID:25596134 NCBI chr 1:78,710,686...78,724,789
Ensembl chr 1:78,710,539...78,724,794
JBrowse link
G Slc22a5 solute carrier family 22 member 5 decreases expression EXP Ifosfamide results in decreased expression of SLC22A5 mRNA; Ifosfamide results in decreased expression of SLC22A5 protein CTD PMID:22701146 NCBI chr10:39,201,101...39,228,090
Ensembl chr10:39,201,107...39,323,853
JBrowse link
G Slc25a20 solute carrier family 25 member 20 increases expression ISO Ifosfamide results in increased expression of SLC25A20 mRNA CTD PMID:25596134 NCBI chr 8:117,455,308...117,476,762
Ensembl chr 8:117,455,262...117,476,734
JBrowse link
G Slc2a1 solute carrier family 2 member 1 increases expression ISO Ifosfamide results in increased expression of SLC2A1 mRNA CTD PMID:25596134 NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897
JBrowse link
G Slc3a2 solute carrier family 3 member 2 increases expression ISO Ifosfamide results in increased expression of SLC3A2 mRNA CTD PMID:25596134 NCBI chr 1:224,906,566...224,921,029
Ensembl chr 1:224,906,554...224,921,092
JBrowse link
G Slc6a9 solute carrier family 6 member 9 decreases expression ISO Ifosfamide results in decreased expression of SLC6A9 mRNA CTD PMID:25596134 NCBI chr 5:136,669,674...136,703,702
Ensembl chr 5:136,669,674...136,703,697
JBrowse link
G Slc7a5 solute carrier family 7 member 5 increases expression ISO Ifosfamide results in increased expression of SLC7A5 mRNA CTD PMID:25596134 NCBI chr19:54,693,959...54,722,563
Ensembl chr19:54,693,959...54,722,563
JBrowse link
G Son SON DNA and RNA binding protein decreases expression ISO Ifosfamide results in decreased expression of SON mRNA CTD PMID:25596134 NCBI chr11:31,806,598...31,837,769
Ensembl chr11:31,806,618...31,837,763
JBrowse link
G Spsb1 splA/ryanodine receptor domain and SOCS box containing 1 increases expression ISO Ifosfamide results in increased expression of SPSB1 mRNA CTD PMID:25596134 NCBI chr 5:166,913,734...166,978,534
Ensembl chr 5:166,913,735...166,926,636
JBrowse link
G Sqstm1 sequestosome 1 increases expression ISO Ifosfamide results in increased expression of SQSTM1 mRNA CTD PMID:25596134 NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
JBrowse link
G Srd5a3 steroid 5 alpha-reductase 3 decreases expression ISO Ifosfamide results in decreased expression of SRD5A3 mRNA CTD PMID:25596134 NCBI chr14:34,554,769...34,570,423
Ensembl chr14:34,556,220...34,570,356
JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO Ifosfamide results in increased expression of SRXN1 mRNA CTD PMID:25596134 NCBI chr 3:147,608,850...147,614,410
Ensembl chr 3:147,609,095...147,632,801
JBrowse link
G Sulf2 sulfatase 2 decreases expression ISO Ifosfamide results in decreased expression of SULF2 mRNA CTD PMID:25596134 NCBI chr 3:162,791,349...162,872,984
Ensembl chr 3:162,791,355...162,872,831
JBrowse link
G Taldo1 transaldolase 1 increases expression ISO Ifosfamide results in increased expression of TALDO1 mRNA CTD PMID:25596134 NCBI chr 1:214,375,555...214,385,886
Ensembl chr 1:214,375,515...214,385,885
JBrowse link
G Tars1 threonyl-tRNA synthetase 1 decreases expression ISO Ifosfamide results in decreased expression of TARS1 mRNA CTD PMID:25596134 NCBI chr 2:61,394,632...61,414,115
Ensembl chr 2:61,394,770...61,414,102
JBrowse link
G Tbxas1 thromboxane A synthase 1 increases expression ISO Ifosfamide results in increased expression of TBXAS1 mRNA CTD PMID:25596134 NCBI chr 4:66,624,181...66,846,745
Ensembl chr 4:66,670,618...66,846,805
JBrowse link
G Tfap2a transcription factor AP-2 alpha decreases expression ISO Ifosfamide results in decreased expression of TFAP2A mRNA CTD PMID:25596134 NCBI chr17:24,653,342...24,670,457
Ensembl chr17:24,654,902...24,670,457
JBrowse link
G Thbs2 thrombospondin 2 decreases expression ISO Ifosfamide results in decreased expression of THBS2 mRNA CTD PMID:25596134 NCBI chr 1:56,653,929...56,683,571
Ensembl chr 1:56,653,938...56,683,731
JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase increases expression ISO Ifosfamide results in increased expression of TIGAR mRNA CTD PMID:25596134 NCBI chr 4:159,635,145...159,654,108
Ensembl chr 4:159,635,153...159,654,063
JBrowse link
G Timm17b translocase of inner mitochondrial membrane 17b decreases expression ISO Ifosfamide results in decreased expression of TIMM17B mRNA CTD PMID:25596134 NCBI chr  X:15,441,369...15,448,452
Ensembl chr  X:15,441,651...15,448,403
JBrowse link
G Tlr4 toll-like receptor 4 increases expression ISO Ifosfamide results in increased expression of TLR4 mRNA CTD PMID:25596134 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tmtc2 transmembrane O-mannosyltransferase targeting cadherins 2 decreases expression ISO Ifosfamide results in decreased expression of TMTC2 mRNA CTD PMID:25596134 NCBI chr 7:47,179,596...47,586,777
Ensembl chr 7:47,181,981...47,586,137
JBrowse link
G Tnf tumor necrosis factor increases secretion
increases expression
multiple interactions
EXP Ifosfamide results in increased secretion of TNF protein
Ifosfamide results in increased expression of TNF protein
morin inhibits the reaction [Ifosfamide results in increased expression of TNF protein]; Resveratrol inhibits the reaction [Ifosfamide results in increased secretion of TNF protein]
CTD PMID:17481685, PMID:31722249 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfaip8 TNF alpha induced protein 8 increases expression ISO Ifosfamide results in increased expression of TNFAIP8 mRNA CTD PMID:25596134 NCBI chr18:44,664,310...44,779,914
Ensembl chr18:44,716,226...44,779,914
JBrowse link
G Tnfsf9 TNF superfamily member 9 increases expression ISO Ifosfamide results in increased expression of TNFSF9 mRNA CTD PMID:25596134 NCBI chr 9:9,909,942...9,912,276
Ensembl chr 9:9,909,948...9,912,276
JBrowse link
G Top1 DNA topoisomerase I increases expression ISO Ifosfamide results in increased expression of TOP1 mRNA CTD PMID:25596134 NCBI chr 3:156,635,688...156,717,686
Ensembl chr 3:156,642,464...156,717,686
JBrowse link
G Top2a DNA topoisomerase II alpha multiple interactions ISO TOP2A results in decreased susceptibility to [Carboplatin co-treated with Etoposide co-treated with Ifosfamide] CTD PMID:11325482 NCBI chr10:86,901,467...86,930,947
Ensembl chr10:86,901,007...86,932,154
JBrowse link
G Tp53 tumor protein p53 affects activity
multiple interactions
increases expression
ISO
EXP
Ifosfamide affects the activity of TP53 protein
morin inhibits the reaction [Ifosfamide results in increased expression of TP53 protein]
CTD PMID:25596134, PMID:31722249 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tp53i3 tumor protein p53 inducible protein 3 increases expression ISO Ifosfamide results in increased expression of TP53I3 mRNA CTD PMID:25596134 NCBI chr13:75,101,759...75,145,967
Ensembl chr13:75,105,615...75,143,441
JBrowse link
G Tp53inp1 tumor protein p53 inducible nuclear protein 1 increases expression ISO Ifosfamide results in increased expression of TP53INP1 mRNA CTD PMID:25596134 NCBI chr 5:24,402,895...24,419,651
Ensembl chr 5:24,410,863...24,416,888
JBrowse link
G Trafd1 TRAF type zinc finger domain containing 1 increases expression ISO Ifosfamide results in increased expression of TRAFD1 mRNA CTD PMID:25596134 NCBI chr12:40,695,520...40,709,438
Ensembl chr12:40,695,520...40,709,462
JBrowse link
G Triap1 TP53 regulated inhibitor of apoptosis 1 increases expression ISO Ifosfamide results in increased expression of TRIAP1 mRNA CTD PMID:25596134 NCBI chr12:46,987,404...46,989,906
Ensembl chr12:46,987,404...46,989,897
Ensembl chr12:46,987,404...46,989,897
JBrowse link
G Tspan12 tetraspanin 12 decreases expression ISO Ifosfamide results in decreased expression of TSPAN12 mRNA CTD PMID:25596134 NCBI chr 4:48,852,823...48,953,240
Ensembl chr 4:48,852,827...48,928,372
JBrowse link
G Txn1 thioredoxin 1 increases expression ISO Ifosfamide results in increased expression of TXN mRNA CTD PMID:25596134 NCBI chr 5:75,049,735...75,057,731
Ensembl chr 5:75,049,747...75,057,752
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO Ifosfamide results in increased expression of TXNRD1 mRNA CTD PMID:25596134 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
JBrowse link
G Ube2g2 ubiquitin-conjugating enzyme E2G 2 increases expression ISO Ifosfamide results in increased expression of UBE2G2 mRNA CTD PMID:25596134 NCBI chr20:11,700,089...11,721,823
Ensembl chr20:11,700,089...11,721,838
JBrowse link
G Unkl unk like zinc finger increases expression ISO Ifosfamide results in increased expression of UNKL mRNA CTD PMID:25596134 NCBI chr10:14,547,126...14,593,090
Ensembl chr10:14,547,172...14,590,762
JBrowse link
G Usp3 ubiquitin specific peptidase 3 increases expression ISO Ifosfamide results in increased expression of USP3 mRNA CTD PMID:25596134 NCBI chr 8:72,207,970...72,284,871
Ensembl chr 8:72,207,972...72,284,873
JBrowse link
G Vars1 valyl-tRNA synthetase 1 increases expression ISO Ifosfamide results in increased expression of VARS1 mRNA CTD PMID:25596134 NCBI chr20:4,993,539...5,008,259
Ensembl chr20:4,993,560...5,008,262
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions
decreases expression
ISO IFNA2 promotes the reaction [Ifosfamide results in decreased expression of VEGFA protein]; IFNB1 promotes the reaction [Ifosfamide results in decreased expression of VEGFA protein] CTD PMID:15659795 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Wars1 tryptophanyl-tRNA synthetase 1 increases expression ISO Ifosfamide results in increased expression of WARS1 mRNA CTD PMID:25596134 NCBI chr 6:132,771,026...132,802,262
Ensembl chr 6:132,771,021...132,802,210
JBrowse link
G Wwc2 WW and C2 domain containing 2 decreases expression ISO Ifosfamide results in decreased expression of WWC2 mRNA CTD PMID:25596134 NCBI chr16:47,368,768...47,533,816
Ensembl chr16:47,368,768...47,533,816
JBrowse link
G Xbp1 X-box binding protein 1 affects activity ISO Ifosfamide affects the activity of XBP1 protein CTD PMID:25596134 NCBI chr14:85,753,736...85,758,820
Ensembl chr14:85,753,760...85,758,145
JBrowse link
G Xpc XPC complex subunit, DNA damage recognition and repair factor increases expression ISO Ifosfamide results in increased expression of XPC mRNA CTD PMID:25596134 NCBI chr 4:123,134,457...123,161,985
Ensembl chr 4:123,134,457...123,161,985
JBrowse link
G Yeats2 YEATS domain containing 2 affects expression ISO Ifosfamide affects the expression of YEATS2 mRNA CTD PMID:25596134 NCBI chr11:84,330,064...84,595,296
Ensembl chr11:84,330,064...84,583,542
JBrowse link
G Zmat3 zinc finger, matrin type 3 increases expression ISO Ifosfamide results in increased expression of ZMAT3 mRNA CTD PMID:25596134 NCBI chr 2:118,715,229...118,746,109
Ensembl chr 2:118,721,334...118,745,766
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    role 19732
      chemical role 19248
        solvent 16456
          phosphoric acid 7794
            phosphoramide 1006
              phosphorodiamide 975
                ifosfamides 244
                  4-Hydroxyifosfamide 0
                  4-Ketoifosfamide 0
                  ifosfamide 244
                  trofosfamide 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    p-block element atom 19670
                      chalcogen 19360
                        oxygen atom 19321
                          oxygen molecular entity 19321
                            hydroxides 19066
                              oxoacid 18192
                                pnictogen oxoacid 10144
                                  phosphorus oxoacid 9032
                                    phosphoric acids 7794
                                      phosphoric acid 7794
                                        phosphoramide 1006
                                          phosphorodiamide 975
                                            ifosfamides 244
                                              4-Hydroxyifosfamide 0
                                              4-Ketoifosfamide 0
                                              ifosfamide 244
                                              trofosfamide 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.