Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   


go back to main search page
Accession:CHEBI:55313 term browser browse the term
Definition:An indole alkaloid of the curare family. A neuroblocker, it is often used in chloride form as an anesthesia adjuvant.
Synonyms:exact_synonym: (1R,3aR,9Z,10S,11aS,12R,14aR,19aS,20Z,20bS,21S,22aS,23E,26E)-23,26-bis(2-hydroxyethylidene)-1,12-di(prop-2-en-1-yl)-1,2,3,10,11,11a,12,13,14,21,22,22a-dodecahydro-19aH,20bH-1,21:10,12-diethanodipyrrolo[3,2-f:3,2-f'][1,5]diazocino[3,2,1-jk:7,6,5-j'k']dicarbazole-1,12-diium
 related_synonym: 4,4'-Didemethyl-4,4'-di-2-propenyl-toxiferine I (9CI);   Alcuronum;   Alloferine;   Diallylbis(nortoxiferine);   Diallylnortoxiferine;   Diallyltoxiferine;   Formula=C44H50N4O2;   InChI=1S/C44H50N4O2/c1-3-17-47-19-15-43-35-9-5-7-11-37(35)45-26-34-32-24-40-44(16-20-48(40,18-4-2)28-30(32)14-22-50)36-10-6-8-12-38(36)46(42(34)44)25-33(41(43)45)31(23-39(43)47)29(27-47)13-21-49/h3-14,25-26,31-32,39-42,49-50H,1-2,15-24,27-28H2/q+2/b29-13-,30-14-,33-25-,34-26-/t31-,32-,39-,40-,41-,42-,43+,44+,47-,48-/m0/s1;   InChIKey=MUQUYTSLDVKIOF-CHJKCJHBSA-N;   N,N'-Diallylnortoxiferinium;   N,N'-diallyl-bis-nor-toxiferine;   SMILES=[H][C@]12C[C@@]3([H])[C@@]4(CC[N@@+]3(CC=C)C\\C1=C\\CO)c1ccccc1N1\\C=C3\\[C@@]5([H])C[C@@]6([H])[C@@]7(CC[N@@+]6(CC=C)C\\C5=C\\CO)c5ccccc5N(\\C=C2/[C@@]41[H])[C@@]37[H]
 xref: Beilstein:4101239 "Beilstein";   CAS:23214-96-2 "ChemIDplus"
 xref_mesh: MESH:D000443
 xref: PMID:12039641 "Europe PMC";   PMID:6196640 "Europe PMC";   PMID:7818127 "Europe PMC";   Reaxys:4101239 "Reaxys"

show annotations for term's descendants       view all columns           Sort by:
alcuronium term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Chrm4 cholinergic receptor, muscarinic 4 JBrowse link 3 80,833,272 80,841,165 RGD:6480464
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit JBrowse link 3 176,533,182 176,547,965 RGD:6480464
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit JBrowse link 2 189,088,570 189,096,785 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19654
    role 19598
      biological role 19596
        biochemical role 19125
          metabolite 19093
            alkaloid 5265
              indole alkaloid 1822
                alcuronium 3
                  alcuronium bromide 0
                  alcuronium chloride 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19654
    subatomic particle 19650
      composite particle 19650
        hadron 19650
          baryon 19650
            nucleon 19650
              atomic nucleus 19650
                atom 19650
                  main group element atom 19531
                    p-block element atom 19531
                      carbon group element atom 19413
                        carbon atom 19405
                          organic molecular entity 19405
                            organic group 18331
                              cyclic organic group 1822
                                organic heterobicyclic ring 1822
                                  indole skeleton 1822
                                    indole alkaloid 1822
                                      alcuronium 3
                                        alcuronium bromide 0
                                        alcuronium chloride 0
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.