Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:glyceraldehyde
go back to main search page
Accession:CHEBI:5445 term browser browse the term
Definition:An aldotriose comprising propanal having hydroxy groups at the 2- and 3-positions. It plays role in the formation of advanced glycation end-products (AGEs), a deleterious accompaniment to ageing.
Synonyms:related_synonym: 2,3-Dihydroxypropanal;   2,3-Dihydroxypropionaldehyde;   Aldotriose;   DL-glyceraldehyde;   Formula=C3H6O3;   Glyceraldehyd;   Glycerinaldehyd;   Glyzerinaldehyd;   InChI=1S/C3H6O3/c4-1-3(6)2-5/h1,3,5-6H,2H2;   InChIKey=MNQZXJOMYWMBOU-UHFFFAOYSA-N;   SMILES=[H]C(=O)C(O)CO;   alpha,beta-dihydroxypropionaldehyde;   gliceraldehido;   glyceric aldehyde;   glycerinaldehyde;   glycerinformal;   glycerose
 alt_id: CHEBI:24343;   CHEBI:387614
 xref: Beilstein:635844;   CAS:367-47-5;   CAS:56-82-6;   DrugBank:DB02536;   Gmelin:164389;   HMDB:HMDB0001051;   KEGG:C02154;   KNApSAcK:C00007413
 xref_mesh: MESH:D005985
 xref: MetaCyc:CPD0-1551;   PMID:18087047;   PMID:18256486;   PMID:18791692;   PMID:20371493;   PMID:21707087;   PMID:23543734;   PMID:9506998;   Reaxys:635844;   Wikipedia:Glyceraldehyde


show annotations for term's descendants           Sort by:
 
glyceraldehyde term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1b1 aldo-keto reductase family 1 member B increases reduction ISO AKR1B1 protein results in increased reduction of Glyceraldehyde CTD PMID:19014918 NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 multiple interactions
increases metabolic processing
increases reduction
ISO [AKR1B10 protein co-treated with NADP] affects the reduction of Glyceraldehyde; ciprofibrate inhibits the reaction [AKR1B10 protein results in increased reduction of Glyceraldehyde]; ethyl 1-benzyl-3-hydroxy-2(5H)-oxopyrrole-4-carboxylate inhibits the reaction [AKR1B10 protein results in increased reduction of Glyceraldehyde]; Fenofibrate inhibits the reaction [AKR1B10 protein results in increased reduction of Glyceraldehyde]; fenofibric acid inhibits the reaction [AKR1B10 protein results in increased reduction of Glyceraldehyde]; pirinixic acid inhibits the reaction [AKR1B10 protein results in increased reduction of Glyceraldehyde]; sorbinil inhibits the reaction [AKR1B10 protein results in increased reduction of Glyceraldehyde]; zopolrestat inhibits the reaction [AKR1B10 protein results in increased reduction of Glyceraldehyde]
AKR1B10 protein results in increased metabolism of Glyceraldehyde
CTD PMID:17329238 PMID:18325492 PMID:19014918 PMID:19028477 NCBI chr 4:61,813,265...61,830,371
Ensembl chr 4:61,771,970...61,828,657
JBrowse link
G Akr1b8 aldo-keto reductase family 1, member B8 increases metabolic processing ISO AKR1B15 protein results in increased metabolism of Glyceraldehyde CTD PMID:21276782 NCBI chr 4:61,772,064...61,784,637
Ensembl chr 4:61,771,970...61,828,657
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member multiple interactions EXP [Chloral Hydrate results in decreased activity of ALDH2 protein] which results in increased susceptibility to Glyceraldehyde; [Disulfiram results in decreased activity of ALDH2 protein] which results in increased susceptibility to Glyceraldehyde CTD PMID:21376711 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
G Dhrs3 dehydrogenase/reductase 3 increases metabolic processing ISO DHRS3 protein results in increased metabolism of Glyceraldehyde CTD PMID:25451588 NCBI chr 5:162,809,090...162,843,385
Ensembl chr 5:162,808,646...162,843,383
JBrowse link
G Plcb1 phospholipase C beta 1 multiple interactions EXP PLCB1 protein promotes the reaction [Glyceraldehyde results in increased abundance of Inositol Phosphates] CTD PMID:11377826 NCBI chr 3:127,721,244...128,419,565
Ensembl chr 3:128,155,069...128,419,545
JBrowse link
D-glyceraldehyde term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1b1 aldo-keto reductase family 1 member B increases reduction ISO AKR1B1 protein results in increased reduction of Glyceraldehyde CTD PMID:19014918 NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 multiple interactions
increases reduction
increases metabolic processing
ISO [AKR1B10 protein co-treated with NADP] affects the reduction of Glyceraldehyde; ciprofibrate inhibits the reaction [AKR1B10 protein results in increased reduction of Glyceraldehyde]; ethyl 1-benzyl-3-hydroxy-2(5H)-oxopyrrole-4-carboxylate inhibits the reaction [AKR1B10 protein results in increased reduction of Glyceraldehyde]; Fenofibrate inhibits the reaction [AKR1B10 protein results in increased reduction of Glyceraldehyde]; fenofibric acid inhibits the reaction [AKR1B10 protein results in increased reduction of Glyceraldehyde]; pirinixic acid inhibits the reaction [AKR1B10 protein results in increased reduction of Glyceraldehyde]; sorbinil inhibits the reaction [AKR1B10 protein results in increased reduction of Glyceraldehyde]; zopolrestat inhibits the reaction [AKR1B10 protein results in increased reduction of Glyceraldehyde]
AKR1B10 protein results in increased metabolism of Glyceraldehyde
CTD PMID:17329238 PMID:18325492 PMID:19014918 PMID:19028477 NCBI chr 4:61,813,265...61,830,371
Ensembl chr 4:61,771,970...61,828,657
JBrowse link
G Akr1b8 aldo-keto reductase family 1, member B8 increases metabolic processing ISO AKR1B15 protein results in increased metabolism of Glyceraldehyde CTD PMID:21276782 NCBI chr 4:61,772,064...61,784,637
Ensembl chr 4:61,771,970...61,828,657
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member multiple interactions EXP [Chloral Hydrate results in decreased activity of ALDH2 protein] which results in increased susceptibility to Glyceraldehyde; [Disulfiram results in decreased activity of ALDH2 protein] which results in increased susceptibility to Glyceraldehyde CTD PMID:21376711 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
G Dhrs3 dehydrogenase/reductase 3 increases metabolic processing ISO DHRS3 protein results in increased metabolism of Glyceraldehyde CTD PMID:25451588 NCBI chr 5:162,809,090...162,843,385
Ensembl chr 5:162,808,646...162,843,383
JBrowse link
G Plcb1 phospholipase C beta 1 multiple interactions EXP PLCB1 protein promotes the reaction [Glyceraldehyde results in increased abundance of Inositol Phosphates] CTD PMID:11377826 NCBI chr 3:127,721,244...128,419,565
Ensembl chr 3:128,155,069...128,419,545
JBrowse link
glyceraldehyde 3-phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gapdh glyceraldehyde-3-phosphate dehydrogenase multiple interactions ISO [GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog; Adenosine Diphosphate inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog]; Adenosine Triphosphate inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog]; NAD analog inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog]; NADP inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog] CTD PMID:15788719 NCBI chr 4:157,676,336...157,680,322
Ensembl chr 4:157,676,595...157,679,962
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19817
    role 19767
      biological role 19767
        biochemical role 19315
          metabolite 19296
            fundamental metabolite 12659
              glyceraldehyde 7
                (3E)-3-(methoxyimino)propane-1,2-diol 0
                D-glyceraldehyde + 6
                L-glyceraldehyde + 0
                glyceraldehyde 3-phosphate + 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19817
    subatomic particle 19815
      composite particle 19815
        hadron 19815
          baryon 19815
            nucleon 19815
              atomic nucleus 19815
                atom 19815
                  main group element atom 19705
                    p-block element atom 19705
                      carbon group element atom 19614
                        carbon atom 19603
                          organic molecular entity 19603
                            heteroorganic entity 19202
                              organochalcogen compound 18915
                                organooxygen compound 18838
                                  carbohydrates and carbohydrate derivatives 12252
                                    carbohydrate 12252
                                      monosaccharide 4188
                                        aldose 2558
                                          aldotriose 7
                                            glyceraldehyde 7
                                              (3E)-3-(methoxyimino)propane-1,2-diol 0
                                              D-glyceraldehyde + 6
                                              L-glyceraldehyde + 0
                                              glyceraldehyde 3-phosphate + 1
paths to the root