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ONTOLOGY REPORT - ANNOTATIONS


Term:glipizide
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Accession:CHEBI:5384 term browser browse the term
Definition:An N-sulfonylurea that is glyburide in which the (5-chloro-2-methoxybenzoyl group is replaced by a (5-methylpyrazin-2-yl)carbonyl group. An oral hypoglycemic agent, it is used in the treatment of type 2 diabetes mellitus.
Synonyms:exact_synonym: N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-5-methylpyrazine-2-carboxamide
 related_synonym: 1-cyclohexyl-3-({p-[2-(5-methylpyrazinecarboxamido)ethyl]phenyl}sulfonyl)urea;   Aldiab;   CP 28,720;   CP 28720;   Digrin;   Dipazide;   Formula=C21H27N5O4S;   Glibenese;   Glibetin;   Glican;   Glidiab;   Glipid;   Gluco-Rite;   Glucolip;   Glucotrol;   Glucozide;   Glupitel;   Glupizide;   Glyde;   Glydiazinamide;   InChI=1S/C21H27N5O4S/c1-15-13-24-19(14-23-15)20(27)22-12-11-16-7-9-18(10-8-16)31(29,30)26-21(28)25-17-5-3-2-4-6-17/h7-10,13-14,17H,2-6,11-12H2,1H3,(H,22,27)(H2,25,26,28);   InChIKey=ZJJXGWJIGJFDTL-UHFFFAOYSA-N;   K 4024;   Melizide;   Mindiab;   Minidab;   Minidiab;   Minodiab;   N-{4-[beta-(5-methylpyrazine-2-carboxamido)ethyl]benzenesulphonyl}-N'-cyclohexylurea;   Napizide;   Ozidia;   SMILES=Cc1cnc(cn1)C(=O)NCCc1ccc(cc1)S(=O)(=O)NC(=O)NC1CCCCC1;   Sucrazide;   glipizida;   glipizidum
 xref: CAS:29094-61-9 "ChemIDplus";   DrugBank:DB01067;   Drug_Central:1301 "DrugCentral";   HMDB:HMDB0015200;   KEGG:D00335;   LINCS:LSM-2251
 xref_mesh: MESH:D005913
 xref: PMID:11147395 "Europe PMC";   PMID:20797618 "Europe PMC";   PMID:23230096 "Europe PMC";   PMID:24418334 "Europe PMC";   PMID:24444583 "Europe PMC";   PMID:2665487 "Europe PMC";   PMID:3143256 "Europe PMC";   PMID:389600 "Europe PMC";   PMID:3923454 "Europe PMC";   PMID:7660535 "Europe PMC";   Patent:DE2012138;   Patent:US3669966;   Reaxys:903495 "Reaxys";   Wikipedia:Glipizide


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glipizide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb11 ATP binding cassette subfamily B member 11 JBrowse link 3 55,480,024 55,587,946 RGD:6480464
G Akr1c2 aldo-keto reductase family 1, member C2 JBrowse link 17 69,388,337 69,435,160 RGD:6480464
G Akr1c3 aldo-keto reductase family 1, member C3 JBrowse link 17 69,761,126 69,778,021 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19657
    role 19601
      application 19225
        pharmaceutical 19089
          drug 19089
            hypoglycemic agent 3736
              glipizide 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19657
    subatomic particle 19653
      composite particle 19653
        hadron 19653
          baryon 19653
            nucleon 19653
              atomic nucleus 19653
                atom 19653
                  main group element atom 19534
                    p-block element atom 19534
                      carbon group element atom 19417
                        carbon atom 19409
                          organic molecular entity 19409
                            organic group 18338
                              organic divalent group 18329
                                organodiyl group 18329
                                  carbonyl group 18218
                                    carbonyl compound 18218
                                      carboxylic acid 17918
                                        carboacyl group 16941
                                          univalent carboacyl group 16941
                                            carbamoyl group 16621
                                              carboxamide 16621
                                                monocarboxylic acid amide 13181
                                                  urea 4932
                                                    ureas 4929
                                                      N-sulfonylurea 94
                                                        glipizide 4
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