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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:chloramine T
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Accession:CHEBI:53767 term browser browse the term
Definition:An organic sodium salt derivative of toluene-4-sulfonamide with a chloro substituent in place of an amino hydrogen.
Synonyms:exact_synonym: sodium chloro[(4-methylphenyl)sulfonyl]azanide
 related_synonym: (N-Chloro-p-toluenesulfonamido)sodium;   Acti-chlore;   Chloralone;   Chlorasan;   Chloraseptine;   Chlorazan;   Chlorazene;   Chlorazone;   Chlorina Aktivin;   Chlorosol;   Chlorozone;   Chlorseptol;   Formula=C7H7ClNNaO2S;   Heliogen;   InChI=1S/C7H7ClNO2S.Na/c1-6-2-4-7(5-3-6)12(10,11)9-8;/h2-5H,1H3;/q-1;+1;   InChIKey=VDQQXEISLMTGAB-UHFFFAOYSA-N;   Mannolite;   Monochloramine T;   Multichlor;   SMILES=[Na+].Cc1ccc(cc1)S(=O)(=O)[N-]Cl;   Sodium N-chloro-p-toluenesulfonamide;   Sodium chloramine T;   Sodium p-toluenesulfonchloramide;   Sodium p-toluenesulfonylchloramide;   Sodium tosylchloramide;   Tampules;   Tochlorine;   Tolamine;   Tosilcloramida sodica;   Tosylchloramide sodique;   Tosylchloramidum natricum
 xref: Beilstein:3599375;   CAS:127-65-1;   KEGG:D02445
 xref_mesh: MESH:C016300
 xref: PMID:10513008;   PMID:11601449;   PMID:24195278;   PMID:24213014;   PMID:2758361;   Reaxys:3599375;   Wikipedia:Chloramine_T


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chloramine T term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd86 CD86 molecule increases expression ISO chloramine-T results in increased expression of CD86 protein CTD PMID:19665512 NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795
JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression EXP chloramine-T results in increased expression of GPX1 protein CTD PMID:24213014 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO chloramine-T results in increased expression of HMOX1 mRNA CTD PMID:26244607 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions ISO chloramine-T results in increased oxidation of and results in decreased activity of KCNH2 protein CTD PMID:17624316 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Msra methionine sulfoxide reductase A decreases response to substance
multiple interactions
ISO MSRA protein results in decreased susceptibility to chloramine-T
S-methylcysteine promotes the reaction [MSRA protein results in decreased susceptibility to chloramine-T]
CTD PMID:19085252 NCBI chr15:47,488,333...47,800,662
Ensembl chr15:47,488,894...47,800,024
JBrowse link
G Nrgn neurogranin multiple interactions
affects phosphorylation
EXP Dithiothreitol inhibits the reaction [chloramine-T affects the phosphorylation of NRGN protein] CTD PMID:21241739 NCBI chr 8:40,015,049...40,023,193
Ensembl chr 8:40,015,049...40,023,193
JBrowse link
G Prdx1 peroxiredoxin 1 increases expression EXP chloramine-T results in increased expression of PRDX1 protein CTD PMID:24213014 NCBI chr 5:135,536,413...135,551,986
Ensembl chr 5:135,536,413...135,551,990
JBrowse link
G Selp selectin P decreases expression ISO chloramine-T results in decreased expression of SELP protein CTD PMID:11441983 NCBI chr13:82,428,914...82,464,629
Ensembl chr13:82,429,063...82,464,628
JBrowse link
G Sod2 superoxide dismutase 2 increases expression EXP chloramine-T results in increased expression of SOD2 protein CTD PMID:24213014 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19875
    role 19825
      biological role 19825
        antimicrobial agent 17409
          disinfectant 12303
            chloramine T 9
Path 2
Term Annotations click to browse term
  CHEBI ontology 19875
    subatomic particle 19873
      composite particle 19873
        hadron 19873
          baryon 19873
            nucleon 19873
              atomic nucleus 19873
                atom 19873
                  main group element atom 19763
                    main group molecular entity 19763
                      s-block molecular entity 19511
                        alkali metal molecular entity 10635
                          sodium molecular entity 8646
                            elemental sodium 8646
                              sodium(1+) 8646
                                sodium salt 8646
                                  organic sodium salt 1284
                                    chloramine T 9
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