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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:chloramine T
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Accession:CHEBI:53767 term browser browse the term
Definition:An organic sodium salt derivative of toluene-4-sulfonamide with a chloro substituent in place of an amino hydrogen.
Synonyms:exact_synonym: sodium chloro[(4-methylphenyl)sulfonyl]azanide
 related_synonym: (N-Chloro-p-toluenesulfonamido)sodium;   Acti-chlore;   Chloralone;   Chlorasan;   Chloraseptine;   Chlorazan;   Chlorazene;   Chlorazone;   Chlorina Aktivin;   Chlorosol;   Chlorozone;   Chlorseptol;   Formula=C7H7ClNNaO2S;   Heliogen;   InChI=1S/C7H7ClNO2S.Na/c1-6-2-4-7(5-3-6)12(10,11)9-8;/h2-5H,1H3;/q-1;+1;   InChIKey=VDQQXEISLMTGAB-UHFFFAOYSA-N;   Mannolite;   Monochloramine T;   Multichlor;   SMILES=[Na+].Cc1ccc(cc1)S(=O)(=O)[N-]Cl;   Sodium N-chloro-p-toluenesulfonamide;   Sodium chloramine T;   Sodium p-toluenesulfonchloramide;   Sodium p-toluenesulfonylchloramide;   Sodium tosylchloramide;   Tampules;   Tochlorine;   Tolamine;   Tosilcloramida sodica;   Tosylchloramide sodique;   Tosylchloramidum natricum
 xref: Beilstein:3599375;   CAS:127-65-1;   KEGG:D02445
 xref_mesh: MESH:C016300
 xref: PMID:10513008;   PMID:11601449;   PMID:24195278;   PMID:24213014;   PMID:2758361;   Reaxys:3599375;   Wikipedia:Chloramine_T


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chloramine T term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd86 CD86 molecule increases expression ISO chloramine-T results in increased expression of CD86 protein CTD PMID:19665512 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818 		JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression EXP chloramine-T results in increased expression of GPX1 protein CTD PMID:24213014 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO chloramine-T results in increased expression of HMOX1 mRNA CTD PMID:26244607 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions ISO chloramine-T results in increased oxidation of and results in decreased activity of KCNH2 protein CTD PMID:17624316 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Msra methionine sulfoxide reductase A decreases response to substance
multiple interactions		 ISO MSRA protein results in decreased susceptibility to chloramine-T
S-methylcysteine promotes the reaction [MSRA protein results in decreased susceptibility to chloramine-T]		 CTD PMID:19085252 NCBI chr15:38,363,459...38,677,406
Ensembl chr15:38,351,445...38,676,585 		JBrowse link
G Nrgn neurogranin multiple interactions
affects phosphorylation		 EXP Dithiothreitol inhibits the reaction [chloramine-T affects the phosphorylation of NRGN protein] CTD PMID:21241739 NCBI chr 8:37,255,462...37,263,659
Ensembl chr 8:37,256,930...37,257,516 		JBrowse link
G Prdx1 peroxiredoxin 1 increases expression EXP chloramine-T results in increased expression of PRDX1 protein CTD PMID:24213014 NCBI chr 5:130,147,276...130,162,850
Ensembl chr 5:130,147,204...130,162,856 		JBrowse link
G Selp selectin P decreases expression ISO chloramine-T results in decreased expression of SELP protein CTD PMID:11441983 NCBI chr13:76,476,229...76,511,846
Ensembl chr13:76,476,295...76,511,845 		JBrowse link
G Sod2 superoxide dismutase 2 increases expression EXP chloramine-T results in increased expression of SOD2 protein CTD PMID:24213014 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19818
    role 19790
      biological role 19788
        antimicrobial agent 17945
          disinfectant 13161
            chloramine T 9
Path 2
Term Annotations click to browse term
  CHEBI ontology 19818
    subatomic particle 19816
      composite particle 19816
        hadron 19816
          baryon 19816
            nucleon 19816
              atomic nucleus 19816
                atom 19816
                  main group element atom 19761
                    main group molecular entity 19761
                      s-block molecular entity 19612
                        alkali metal molecular entity 12180
                          sodium molecular entity 10483
                            elemental sodium 10483
                              sodium(1+) 10483
                                sodium salt 10483
                                  organic sodium salt 1375
                                    chloramine T 9
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