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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:HIV-1 reverse transcriptase inhibitor
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Accession:CHEBI:53756 term browser browse the term
Definition:An entity which inhibits the activity of HIV-1 reverse transcriptase.
Synonyms:related_synonym: HIV-1 reverse transcriptase inhibitors;   reverse transcriptase inhibitor;   reverse transcriptase inhibitors


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abacavir term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions
increases export
decreases export
ISO [Estradiol results in decreased activity of ABCG2 protein] which results in increased uptake of abacavir; [isopropyl 5,12-hydroxypentadeca-8,10-dien-6,14-diynoate results in decreased activity of ABCG2 protein] which results in increased uptake of abacavir
3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased export of abacavir]; Elacridar inhibits the reaction [ABCG2 protein results in decreased export of abacavir]; Elacridar inhibits the reaction [ABCG2 protein results in increased export of abacavir]; Nelfinavir inhibits the reaction [ABCG2 protein results in increased export of abacavir]; pluronic block copolymer p85 inhibits the reaction [ABCG2 protein results in increased export of abacavir]
CTD PMID:17437964, PMID:19056916, PMID:25844889 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Alb albumin affects binding
multiple interactions
ISO abacavir binds to ALB protein
abacavir inhibits the reaction [Heme binds to ALB protein]; Heme inhibits the reaction [abacavir binds to ALB protein]
CTD PMID:15814459, PMID:16336266 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 decreases expression ISO abacavir results in decreased expression of ALDH1A2 mRNA CTD PMID:31711903 NCBI chr 8:77,640,234...77,719,488
Ensembl chr 8:77,640,222...77,719,489
JBrowse link
G Crp C-reactive protein increases expression ISO abacavir results in increased expression of CRP protein CTD PMID:19891054 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 decreases expression ISO abacavir results in decreased expression of EYA1 mRNA CTD PMID:31711903 NCBI chr 5:4,275,728...4,495,525
Ensembl chr 5:4,373,626...4,513,142
JBrowse link
G Fgf8 fibroblast growth factor 8 increases expression ISO abacavir results in increased expression of FGF8 mRNA CTD PMID:31711903 NCBI chr 1:265,492,949...265,498,965
Ensembl chr 1:265,493,124...265,498,831
JBrowse link
G Foxc2 forkhead box C2 decreases expression ISO abacavir results in decreased expression of FOXC2 mRNA CTD PMID:31711903 NCBI chr19:53,044,379...53,047,081
Ensembl chr19:53,044,379...53,047,081
JBrowse link
G Gfap glial fibrillary acidic protein increases expression ISO abacavir results in increased expression of GFAP protein CTD PMID:19358275 NCBI chr10:90,990,762...90,999,435
Ensembl chr10:90,990,762...90,999,506
JBrowse link
G Hoxb7 homeo box B7 increases expression ISO abacavir results in increased expression of HOXB7 mRNA CTD PMID:31711903 NCBI chr10:84,135,224...84,138,642
Ensembl chr10:84,135,116...84,138,637
JBrowse link
G Hoxb9 homeo box B9 increases expression ISO abacavir results in increased expression of HOXB9 mRNA CTD PMID:31711903 NCBI chr10:84,119,772...84,124,963
Ensembl chr10:84,119,884...84,123,390
JBrowse link
G Ifng interferon gamma multiple interactions ISO [HLA-B protein polymorphism results in increased susceptibility to abacavir] which results in increased secretion of IFNG protein CTD PMID:23541086 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il13 interleukin 13 multiple interactions ISO [HLA-B protein polymorphism results in increased susceptibility to abacavir] which results in increased secretion of IL13 protein CTD PMID:23541086 NCBI chr10:38,982,909...38,985,466
Ensembl chr10:38,982,909...38,985,466
JBrowse link
G Il4 interleukin 4 affects response to substance ISO IL4 protein affects the susceptibility to abacavir CTD PMID:15867870 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Meox1 mesenchyme homeobox 1 decreases expression ISO abacavir results in decreased expression of MEOX1 mRNA CTD PMID:31711903 NCBI chr10:89,797,011...89,817,009
Ensembl chr10:89,797,038...89,816,491
JBrowse link
G Mesp2 mesoderm posterior bHLH transcription factor 2 decreases expression ISO abacavir results in decreased expression of MESP2 mRNA CTD PMID:31711903 NCBI chr 1:141,550,633...141,553,239
Ensembl chr 1:141,550,633...141,553,230
JBrowse link
G Mmp9 matrix metallopeptidase 9 increases expression ISO abacavir results in increased expression of MMP9 protein CTD PMID:19891054 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mpo myeloperoxidase increases expression ISO abacavir results in increased expression of MPO protein CTD PMID:19891054 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Neurog2 neurogenin 2 increases expression ISO abacavir results in increased expression of NEUROG2 mRNA CTD PMID:31711903 NCBI chr 2:231,962,517...231,963,441
Ensembl chr 2:231,962,517...231,963,308
JBrowse link
G Olig3 oligodendrocyte transcription factor 3 increases expression ISO abacavir results in increased expression of OLIG3 mRNA CTD PMID:31711903 NCBI chr 1:14,797,766...14,799,835
Ensembl chr 1:14,797,766...14,799,835
JBrowse link
G Pax3 paired box 3 decreases expression ISO abacavir results in decreased expression of PAX3 mRNA CTD PMID:31711903 NCBI chr 9:84,004,004...84,101,226
Ensembl chr 9:84,005,183...84,101,172
JBrowse link
G Pax6 paired box 6 increases expression ISO abacavir results in increased expression of PAX6 mRNA CTD PMID:31711903 NCBI chr 3:95,700,241...95,728,682
Ensembl chr 3:95,707,386...95,728,624
JBrowse link
G Slc22a1 solute carrier family 22 member 1 multiple interactions ISO [Quinine results in decreased activity of SLC22A1] which results in decreased uptake of abacavir CTD PMID:25844889 NCBI chr 1:48,273,639...48,300,645
Ensembl chr 1:48,273,611...48,300,655
JBrowse link
G Syp synaptophysin increases expression ISO abacavir results in increased expression of SYP protein CTD PMID:19358275 NCBI chr  X:15,694,699...15,709,244
Ensembl chr  X:15,695,566...15,707,436
JBrowse link
G Tcf15 transcription factor 15 decreases expression ISO abacavir results in decreased expression of TCF15 mRNA CTD PMID:31711903 NCBI chr 3:147,643,250...147,649,511
Ensembl chr 3:147,643,250...147,649,504
JBrowse link
G Tert telomerase reverse transcriptase decreases activity ISO abacavir results in decreased activity of TERT protein CTD PMID:19358275 NCBI chr 1:32,250,876...32,275,330
Ensembl chr 1:32,251,714...32,272,476
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [HLA-B protein polymorphism results in increased susceptibility to abacavir] which results in increased secretion of TNF protein CTD PMID:23541086 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Ucp1 uncoupling protein 1 increases expression ISO abacavir results in increased expression of UCP1 mRNA CTD PMID:14518702 NCBI chr19:24,456,976...24,464,808
Ensembl chr19:24,456,976...24,464,807
JBrowse link
G Uncx UNC homeobox decreases expression ISO abacavir results in decreased expression of UNCX mRNA CTD PMID:31711903 NCBI chr12:17,182,158...17,186,679
Ensembl chr12:17,182,163...17,186,679
JBrowse link
adefovir term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb4 ATP binding cassette subfamily B member 4 multiple interactions
affects transport
EXP Calcitriol promotes the reaction [ABCB4 protein affects the transport of adefovir] CTD PMID:21240898, PMID:21341280 NCBI chr 4:22,133,984...22,192,687
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 affects abundance
increases export
ISO ABCC4 protein affects the abundance of adefovir
ABCC4 protein results in increased export of adefovir
CTD PMID:18364470 NCBI chr15:103,695,415...103,927,980
Ensembl chr15:103,696,557...103,927,592
JBrowse link
G B2m beta-2 microglobulin increases secretion EXP adefovir results in increased secretion of B2M protein CTD PMID:27742868 NCBI chr 3:114,087,287...114,093,311
Ensembl chr 3:114,087,287...114,093,309
JBrowse link
G Calb1 calbindin 1 increases secretion EXP adefovir results in increased secretion of CALB1 protein CTD PMID:27742868 NCBI chr 5:29,538,380...29,562,774
Ensembl chr 5:29,538,380...29,562,773
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 increases secretion EXP adefovir results in increased secretion of HAVCR1 protein CTD PMID:27742868 NCBI chr10:31,813,819...31,860,934
Ensembl chr10:31,813,814...31,848,379
JBrowse link
G Lcn2 lipocalin 2 increases secretion EXP adefovir results in increased secretion of LCN2 protein CTD PMID:27742868 NCBI chr 3:11,414,189...11,417,534
Ensembl chr 3:11,414,186...11,417,546
JBrowse link
G Mmut methylmalonyl-CoA mutase affects expression
increases expression
ISO adefovir affects the expression of MMUT mRNA mutant form; adefovir affects the expression of MMUT protein mutant form
adefovir results in increased expression of MMUT mRNA; adefovir results in increased expression of MMUT protein
CTD PMID:19199343, PMID:19427250 NCBI chr 9:23,323,934...23,352,144
Ensembl chr 9:23,323,936...23,352,668
JBrowse link
G Slc22a6 solute carrier family 22 member 6 increases uptake
affects response to substance
multiple interactions
increases response to substance
EXP
ISO
SLC22A6 protein results in increased uptake of adefovir
SLC22A6 protein affects the susceptibility to adefovir
adefovir inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid]; Probenecid inhibits the reaction [SLC22A6 protein results in increased susceptibility to adefovir]; quercetin 3'-sulfate inhibits the reaction [SLC22A6 protein affects the susceptibility to adefovir]; SLC22A6 protein results in increased uptake of and results in increased susceptibility to adefovir
CTD PMID:16857889, PMID:21244849, PMID:23856525, PMID:25448811 NCBI chr 1:224,824,809...224,833,284
Ensembl chr 1:224,824,799...224,833,259
JBrowse link
G Slc22a8 solute carrier family 22 member 8 increases response to substance ISO SLC22A8 protein results in increased susceptibility to adefovir CTD PMID:25448811 NCBI chr 1:224,799,444...224,818,482
Ensembl chr 1:224,800,252...224,818,482
JBrowse link
G Spp1 secreted phosphoprotein 1 increases secretion EXP adefovir results in increased secretion of SPP1 protein CTD PMID:27742868 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
adefovir pivoxil term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor affects activity ISO adefovir dipivoxil affects the activity of AHR protein CTD PMID:25596134 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Ak4 adenylate kinase 4 increases expression ISO adefovir dipivoxil results in increased expression of AK4 mRNA CTD PMID:25596134 NCBI chr 5:120,250,318...120,309,153
Ensembl chr 5:120,250,616...120,305,897
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 decreases expression ISO adefovir dipivoxil results in decreased expression of AKR1C2 mRNA CTD PMID:25596134 NCBI chr17:69,388,337...69,435,160
Ensembl chr17:69,388,335...69,404,341
JBrowse link
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 decreases expression ISO adefovir dipivoxil results in decreased expression of ALDH18A1 mRNA CTD PMID:25596134 NCBI chr 1:259,641,673...259,674,521
Ensembl chr 1:259,641,676...259,674,425
Ensembl chr 1:259,641,676...259,674,425
JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 increases expression ISO adefovir dipivoxil results in increased expression of ALDH1A3 mRNA CTD PMID:25596134 NCBI chr 1:127,302,920...127,337,828
Ensembl chr 1:127,301,128...127,337,882
JBrowse link
G Als2cl ALS2 C-terminal like increases expression ISO adefovir dipivoxil results in increased expression of ALS2CL mRNA CTD PMID:25596134 NCBI chr 8:119,156,081...119,176,680
Ensembl chr 8:119,160,731...119,174,830
JBrowse link
G Angptl4 angiopoietin-like 4 increases expression ISO adefovir dipivoxil results in increased expression of ANGPTL4 mRNA CTD PMID:25596134 NCBI chr 7:18,627,814...18,634,043
Ensembl chr 7:18,627,808...18,634,079
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) decreases expression ISO adefovir dipivoxil results in decreased expression of ASNS mRNA CTD PMID:25596134 NCBI chr 4:33,742,876...33,761,106
Ensembl chr 4:33,743,364...33,761,163
JBrowse link
G Atad2 ATPase family, AAA domain containing 2 increases expression ISO adefovir dipivoxil results in increased expression of ATAD2 mRNA CTD PMID:25596134 NCBI chr 7:97,984,754...98,027,379
Ensembl chr 7:97,984,862...98,026,052
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO adefovir dipivoxil results in increased expression of ATF3 mRNA CTD PMID:25596134 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Aurkb aurora kinase B increases expression ISO adefovir dipivoxil results in increased expression of AURKB mRNA CTD PMID:25596134 NCBI chr10:55,625,860...55,632,399
Ensembl chr10:55,626,741...55,634,991
JBrowse link
G Axl Axl receptor tyrosine kinase increases expression ISO adefovir dipivoxil results in increased expression of AXL mRNA CTD PMID:25596134 NCBI chr 1:82,550,892...82,580,761
Ensembl chr 1:82,549,420...82,580,761
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO adefovir dipivoxil results in increased expression of BAX mRNA CTD PMID:25596134 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bend5 BEN domain containing 5 decreases expression ISO adefovir dipivoxil results in decreased expression of BEND5 mRNA CTD PMID:25596134 NCBI chr 5:131,257,127...131,312,335
Ensembl chr 5:131,257,127...131,312,335
JBrowse link
G Bmf Bcl2 modifying factor decreases expression ISO adefovir dipivoxil results in decreased expression of BMF mRNA CTD PMID:25596134 NCBI chr 3:110,303,515...110,324,125
Ensembl chr 3:110,306,067...110,324,084
JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO adefovir dipivoxil results in increased expression of BTG2 mRNA CTD PMID:25596134 NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982
JBrowse link
G Ccne2 cyclin E2 increases expression ISO adefovir dipivoxil results in increased expression of CCNE2 mRNA CTD PMID:25596134 NCBI chr 5:24,434,077...24,446,406
Ensembl chr 5:24,434,872...24,446,406
JBrowse link
G Cdk6 cyclin-dependent kinase 6 increases expression ISO adefovir dipivoxil results in increased expression of CDK6 mRNA CTD PMID:25596134 NCBI chr 4:27,781,728...27,969,653
Ensembl chr 4:27,785,647...27,966,398
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO adefovir dipivoxil results in increased expression of CDKN1A mRNA CTD PMID:25596134 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cmbl carboxymethylenebutenolidase homolog increases expression ISO adefovir dipivoxil results in increased expression of CMBL mRNA CTD PMID:25596134 NCBI chr 2:84,645,084...84,666,836
Ensembl chr 2:84,645,084...84,666,835
JBrowse link
G Coch cochlin increases expression ISO adefovir dipivoxil results in increased expression of COCH mRNA CTD PMID:25596134 NCBI chr 6:72,359,702...72,373,710
Ensembl chr 6:72,359,791...72,373,695
JBrowse link
G Col4a1 collagen type IV alpha 1 chain decreases expression ISO adefovir dipivoxil results in decreased expression of COL4A1 mRNA CTD PMID:25596134 NCBI chr16:83,522,162...83,632,153
Ensembl chr16:83,522,162...83,632,153
JBrowse link
G Cth cystathionine gamma-lyase decreases expression ISO adefovir dipivoxil results in decreased expression of CTH mRNA CTD PMID:25596134 NCBI chr 2:264,266,959...264,293,040
Ensembl chr 2:264,266,984...264,293,046
JBrowse link
G Ctsc cathepsin C decreases expression ISO adefovir dipivoxil results in decreased expression of CTSC mRNA CTD PMID:25596134 NCBI chr 1:151,918,514...151,949,979
Ensembl chr 1:151,918,571...151,949,983
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO adefovir dipivoxil results in increased expression of CYP1B1 mRNA CTD PMID:25596134 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Ddb2 damage specific DNA binding protein 2 increases expression ISO adefovir dipivoxil results in increased expression of DDB2 mRNA CTD PMID:25596134 NCBI chr 3:80,030,437...80,052,984
Ensembl chr 3:80,030,437...80,052,953
JBrowse link
G Dgka diacylglycerol kinase, alpha increases expression ISO adefovir dipivoxil results in increased expression of DGKA mRNA CTD PMID:25596134 NCBI chr 7:3,143,826...3,170,764
Ensembl chr 7:3,143,827...3,170,146
JBrowse link
G Dlgap5 DLG associated protein 5 increases expression ISO adefovir dipivoxil results in increased expression of DLGAP5 mRNA CTD PMID:25596134 NCBI chr15:24,167,484...24,199,417
Ensembl chr15:24,167,486...24,199,341
JBrowse link
G Dlx1 distal-less homeobox 1 decreases expression ISO adefovir dipivoxil results in decreased expression of DLX1 mRNA CTD PMID:25596134 NCBI chr 3:58,164,931...58,169,521
Ensembl chr 3:58,164,931...58,169,521
JBrowse link
G Dnai3 dynein axonemal intermediate chain 3 increases expression ISO adefovir dipivoxil results in increased expression of DNAI3 mRNA CTD PMID:25596134 NCBI chr 2:251,912,432...251,970,699
Ensembl chr 2:251,912,368...251,970,768
JBrowse link
G Dpysl3 dihydropyrimidinase-like 3 increases expression ISO adefovir dipivoxil results in increased expression of DPYSL3 mRNA CTD PMID:25596134 NCBI chr18:37,716,371...37,819,347
Ensembl chr18:37,716,143...37,819,097
JBrowse link
G Efna1 ephrin A1 decreases expression ISO adefovir dipivoxil results in decreased expression of EFNA1 mRNA CTD PMID:25596134 NCBI chr 2:188,588,808...188,596,156
Ensembl chr 2:188,588,796...188,596,222
JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha increases expression ISO adefovir dipivoxil results in increased expression of ERO1A mRNA CTD PMID:25596134 NCBI chr15:19,619,947...19,655,381
Ensembl chr15:19,619,973...19,655,381
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO adefovir dipivoxil results in increased expression of FAS mRNA CTD PMID:25596134 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Fbxo22 F-box protein 22 increases expression ISO adefovir dipivoxil results in increased expression of FBXO22 mRNA CTD PMID:25596134 NCBI chr 8:59,770,032...59,786,061
Ensembl chr 8:59,769,994...59,786,065
JBrowse link
G Gabarapl1 GABA type A receptor associated protein like 1 decreases expression ISO adefovir dipivoxil results in decreased expression of GABARAPL1 mRNA CTD PMID:25596134 NCBI chr 4:163,293,724...163,302,866
Ensembl chr 4:163,293,724...163,302,858
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO adefovir dipivoxil results in increased expression of GADD45A mRNA CTD PMID:25596134 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Galnt16 polypeptide N-acetylgalactosaminyltransferase 16 decreases expression ISO adefovir dipivoxil results in decreased expression of GALNT16 mRNA CTD PMID:25596134 NCBI chr 6:104,069,853...104,250,177
Ensembl chr 6:104,068,547...104,250,174
JBrowse link
G Gcnt3 glucosaminyl (N-acetyl) transferase 3, mucin type increases expression ISO adefovir dipivoxil results in increased expression of GCNT3 mRNA CTD PMID:25596134 NCBI chr 8:76,449,078...76,459,431
Ensembl chr 8:76,449,081...76,452,554
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO adefovir dipivoxil results in increased expression of GDF15 mRNA CTD PMID:25596134 NCBI chr16:20,555,395...20,557,978
Ensembl chr16:20,555,395...20,557,978
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 decreases expression ISO adefovir dipivoxil results in decreased expression of GOT1 mRNA CTD PMID:25596134 NCBI chr 1:263,246,248...263,269,762
Ensembl chr 1:263,246,248...263,269,762
JBrowse link
G Gpr87 G protein-coupled receptor 87 increases expression ISO adefovir dipivoxil results in increased expression of GPR87 mRNA CTD PMID:25596134 NCBI chr 2:149,398,949...149,418,041
Ensembl chr 2:149,398,949...149,417,212
JBrowse link
G H1f2 H1.2 linker histone, cluster member increases expression ISO adefovir dipivoxil results in increased expression of H1-2 mRNA CTD PMID:25596134 NCBI chr17:43,638,938...43,640,445
Ensembl chr17:43,639,749...43,640,387
JBrowse link
G Hmox1 heme oxygenase 1 decreases expression ISO adefovir dipivoxil results in decreased expression of HMOX1 mRNA CTD PMID:25596134 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B decreases expression ISO adefovir dipivoxil results in decreased expression of HSPA1B mRNA CTD PMID:25596134 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
JBrowse link
G Ifng interferon gamma multiple interactions ISO adefovir dipivoxil inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased activity of NOS2 protein]; adefovir dipivoxil inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; adefovir dipivoxil inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 protein] CTD PMID:9354585 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il19 interleukin 19 increases secretion ISO adefovir dipivoxil results in increased secretion of IL19 protein CTD PMID:24714768 NCBI chr13:47,663,592...47,677,869
Ensembl chr13:47,664,080...47,670,407
JBrowse link
G Kat6b lysine acetyltransferase 6B decreases expression ISO adefovir dipivoxil results in decreased expression of KAT6B mRNA CTD PMID:25596134 NCBI chr15:2,811,933...2,966,833
Ensembl chr15:2,813,537...2,966,576
JBrowse link
G Kdm3a lysine demethylase 3A decreases expression ISO adefovir dipivoxil results in decreased expression of KDM3A mRNA CTD PMID:25596134 NCBI chr 4:99,503,160...99,547,315
Ensembl chr 4:99,503,176...99,546,905
JBrowse link
G Krt15 keratin 15 increases expression ISO adefovir dipivoxil results in increased expression of KRT15 mRNA CTD PMID:25596134 NCBI chr10:88,046,803...88,050,622
Ensembl chr10:88,046,803...88,050,622
JBrowse link
G Lama3 laminin subunit alpha 3 increases expression ISO adefovir dipivoxil results in increased expression of LAMA3 mRNA CTD PMID:25596134 NCBI chr18:3,704,866...3,941,215
Ensembl chr18:3,705,916...3,940,838
JBrowse link
G Lcn2 lipocalin 2 increases secretion ISO adefovir dipivoxil results in increased secretion of LCN2 protein CTD PMID:24714768 NCBI chr 3:11,414,189...11,417,534
Ensembl chr 3:11,414,186...11,417,546
JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 increases expression ISO adefovir dipivoxil results in increased expression of MAP3K8 mRNA CTD PMID:25596134 NCBI chr17:56,109,403...56,129,925
Ensembl chr17:56,109,549...56,129,919
JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression ISO adefovir dipivoxil results in increased expression of MDM2 mRNA CTD PMID:25596134 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Mxi1 MAX interactor 1, dimerization protein decreases expression ISO adefovir dipivoxil results in decreased expression of MXI1 mRNA CTD PMID:25596134 NCBI chr 1:274,030,748...274,090,071
Ensembl chr 1:274,030,978...274,090,071
JBrowse link
G Ncapd2 non-SMC condensin I complex, subunit D2 increases expression ISO adefovir dipivoxil results in increased expression of NCAPD2 mRNA CTD PMID:25596134 NCBI chr 4:157,682,855...157,705,903
Ensembl chr 4:157,683,077...157,704,596
JBrowse link
G Ninj1 ninjurin 1 increases expression ISO adefovir dipivoxil results in increased expression of NINJ1 mRNA CTD PMID:25596134 NCBI chr17:15,866,235...15,881,284
Ensembl chr17:15,866,237...15,881,327
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO adefovir dipivoxil inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased activity of NOS2 protein]; adefovir dipivoxil inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; adefovir dipivoxil inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 protein] CTD PMID:9354585 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 decreases expression ISO adefovir dipivoxil results in decreased expression of NQO1 mRNA CTD PMID:25596134 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nrep neuronal regeneration related protein decreases expression ISO adefovir dipivoxil results in decreased expression of NREP mRNA CTD PMID:25596134 NCBI chr18:26,183,753...26,212,796
Ensembl chr18:26,185,259...26,211,445
JBrowse link
G Ntpcr nucleoside-triphosphatase, cancer-related increases expression ISO adefovir dipivoxil results in increased expression of NTPCR mRNA CTD PMID:25596134 NCBI chr19:58,565,576...58,579,276
Ensembl chr19:58,565,576...58,579,265
JBrowse link
G P4ha1 prolyl 4-hydroxylase subunit alpha 1 decreases expression ISO adefovir dipivoxil results in decreased expression of P4HA1 mRNA CTD PMID:25596134 NCBI chr20:28,920,616...28,972,576
Ensembl chr20:28,920,616...28,971,966
JBrowse link
G Pank1 pantothenate kinase 1 decreases expression ISO adefovir dipivoxil results in decreased expression of PANK1 mRNA CTD PMID:25596134 NCBI chr 1:253,115,400...253,189,643
Ensembl chr 1:253,119,112...253,185,533
JBrowse link
G Pdia5 protein disulfide isomerase family A, member 5 increases expression ISO adefovir dipivoxil results in increased expression of PDIA5 mRNA CTD PMID:25596134 NCBI chr11:68,493,035...68,578,999
Ensembl chr11:68,493,035...68,578,995
JBrowse link
G Pdlim1 PDZ and LIM domain 1 increases expression ISO adefovir dipivoxil results in increased expression of PDLIM1 mRNA CTD PMID:25596134 NCBI chr 1:259,308,326...259,357,006
Ensembl chr 1:259,308,296...259,357,056
JBrowse link
G Pgr progesterone receptor multiple interactions ISO adefovir dipivoxil binds to and results in decreased activity of PGR protein CTD PMID:25752796 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Phlda3 pleckstrin homology-like domain, family A, member 3 increases expression ISO adefovir dipivoxil results in increased expression of PHLDA3 mRNA CTD PMID:25596134 NCBI chr13:52,588,917...52,592,002
Ensembl chr13:52,588,917...52,592,001
JBrowse link
G Pidd1 p53-induced death domain protein 1 increases expression ISO adefovir dipivoxil results in increased expression of PIDD1 mRNA CTD PMID:25596134 NCBI chr 1:214,418,751...214,423,959
Ensembl chr 1:214,419,240...214,423,881
JBrowse link
G Pir pirin increases expression ISO adefovir dipivoxil results in increased expression of PIR mRNA CTD PMID:25596134 NCBI chr  X:31,852,322...31,968,152
Ensembl chr  X:31,852,323...31,968,152
JBrowse link
G Plec plectin increases expression ISO adefovir dipivoxil results in increased expression of PLEC mRNA CTD PMID:25596134 NCBI chr 7:117,230,319...117,291,859
Ensembl chr 7:117,230,319...117,289,961
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression ISO adefovir dipivoxil results in increased expression of PMAIP1 mRNA CTD PMID:25596134 NCBI chr18:62,159,128...62,179,635
Ensembl chr18:62,174,670...62,181,102
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects activity ISO adefovir dipivoxil affects the activity of PPARG protein CTD PMID:25596134 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ppm1d protein phosphatase, Mg2+/Mn2+ dependent, 1D increases expression ISO adefovir dipivoxil results in increased expression of PPM1D mRNA CTD PMID:25596134 NCBI chr10:72,909,550...72,945,884
Ensembl chr10:72,909,550...72,945,884
JBrowse link
G Prc1 protein regulator of cytokinesis 1 increases expression ISO adefovir dipivoxil results in increased expression of PRC1 mRNA CTD PMID:25596134 NCBI chr 1:142,087,181...142,108,746
Ensembl chr 1:142,087,208...142,108,746
JBrowse link
G Prdm1 PR/SET domain 1 increases expression ISO adefovir dipivoxil results in increased expression of PRDM1 mRNA CTD PMID:25596134 NCBI chr20:49,464,921...49,556,623
Ensembl chr20:49,464,919...49,556,518
JBrowse link
G Prkab2 protein kinase AMP-activated non-catalytic subunit beta 2 decreases expression ISO adefovir dipivoxil results in decreased expression of PRKAB2 mRNA CTD PMID:25596134 NCBI chr 2:199,831,990...199,847,623
Ensembl chr 2:199,831,990...199,847,629
JBrowse link
G Psat1 phosphoserine aminotransferase 1 decreases expression ISO adefovir dipivoxil results in decreased expression of PSAT1 mRNA CTD PMID:25596134 NCBI chr 1:233,124,089...233,145,941
Ensembl chr 1:233,124,092...233,145,941
JBrowse link
G Rara retinoic acid receptor, alpha decreases expression ISO adefovir dipivoxil results in decreased expression of RARA mRNA CTD PMID:25596134 NCBI chr10:86,838,819...86,884,224
Ensembl chr10:86,860,685...86,884,210
JBrowse link
G Rps27l ribosomal protein S27-like increases expression ISO adefovir dipivoxil results in increased expression of RPS27L mRNA CTD PMID:25596134 NCBI chr 8:72,741,155...72,746,090
Ensembl chr 8:72,741,155...72,746,090
JBrowse link
G Rrm2b ribonucleotide reductase regulatory TP53 inducible subunit M2B increases expression ISO adefovir dipivoxil results in increased expression of RRM2B mRNA CTD PMID:25596134 NCBI chr 7:76,750,045...76,780,817
Ensembl chr 7:76,750,050...76,780,817
JBrowse link
G Serpinb5 serpin family B member 5 increases expression ISO adefovir dipivoxil results in increased expression of SERPINB5 mRNA CTD PMID:25596134 NCBI chr13:26,903,052...26,923,250
Ensembl chr13:26,903,052...26,923,250
JBrowse link
G Sesn1 sestrin 1 increases expression ISO adefovir dipivoxil results in increased expression of SESN1 mRNA CTD PMID:25596134 NCBI chr20:46,667,116...46,758,306
Ensembl chr20:46,667,121...46,758,305
JBrowse link
G Sfn stratifin increases expression ISO adefovir dipivoxil results in increased expression of SFN mRNA CTD PMID:25596134 NCBI chr 5:151,823,422...151,824,937
Ensembl chr 5:151,823,887...151,824,633
JBrowse link
G Sh3tc1 SH3 domain and tetratricopeptide repeats 1 decreases expression ISO adefovir dipivoxil results in decreased expression of SH3TC1 mRNA CTD PMID:25596134 NCBI chr14:80,184,814...80,229,207
Ensembl chr14:80,195,715...80,229,214
JBrowse link
G Slc27a2 solute carrier family 27 member 2 decreases expression ISO adefovir dipivoxil results in decreased expression of SLC27A2 mRNA CTD PMID:25596134 NCBI chr 3:119,014,620...119,052,531
Ensembl chr 3:119,014,620...119,052,531
JBrowse link
G Slc6a9 solute carrier family 6 member 9 decreases expression ISO adefovir dipivoxil results in decreased expression of SLC6A9 mRNA CTD PMID:25596134 NCBI chr 5:136,669,674...136,703,702
Ensembl chr 5:136,669,674...136,703,697
JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 increases expression ISO adefovir dipivoxil results in increased expression of SLCO2B1 mRNA CTD PMID:25596134 NCBI chr 1:164,623,313...164,671,612
Ensembl chr 1:164,623,599...164,671,577
JBrowse link
G Smap1 small ArfGAP 1 decreases expression ISO adefovir dipivoxil results in decreased expression of SMAP1 mRNA CTD PMID:25596134 NCBI chr 9:30,068,888...30,161,753
Ensembl chr 9:30,068,659...30,161,578
JBrowse link
G Sulf2 sulfatase 2 increases expression ISO adefovir dipivoxil results in increased expression of SULF2 mRNA CTD PMID:25596134 NCBI chr 3:162,791,349...162,872,984
Ensembl chr 3:162,791,355...162,872,831
JBrowse link
G Thra thyroid hormone receptor alpha multiple interactions ISO adefovir dipivoxil binds to and results in decreased activity of THRA protein CTD PMID:25752796 NCBI chr10:86,657,285...86,684,935
Ensembl chr10:86,657,285...86,684,933
JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase increases expression ISO adefovir dipivoxil results in increased expression of TIGAR mRNA CTD PMID:25596134 NCBI chr 4:159,635,145...159,654,108
Ensembl chr 4:159,635,153...159,654,063
JBrowse link
G Tiparp TCDD-inducible poly(ADP-ribose) polymerase increases expression ISO adefovir dipivoxil results in increased expression of TIPARP mRNA CTD PMID:25596134 NCBI chr 2:157,316,293...157,342,979
Ensembl chr 2:157,316,266...157,341,469
JBrowse link
G Tnfsf9 TNF superfamily member 9 increases expression ISO adefovir dipivoxil results in increased expression of TNFSF9 mRNA CTD PMID:25596134 NCBI chr 9:9,909,942...9,912,276
Ensembl chr 9:9,909,948...9,912,276
JBrowse link
G Tp53 tumor protein p53 affects activity ISO adefovir dipivoxil affects the activity of TP53 protein CTD PMID:25596134 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tp53inp1 tumor protein p53 inducible nuclear protein 1 increases expression ISO adefovir dipivoxil results in increased expression of TP53INP1 mRNA CTD PMID:25596134 NCBI chr 5:24,402,895...24,419,651
Ensembl chr 5:24,410,863...24,416,888
JBrowse link
G Trafd1 TRAF type zinc finger domain containing 1 decreases expression ISO adefovir dipivoxil results in decreased expression of TRAFD1 mRNA CTD PMID:25596134 NCBI chr12:40,695,520...40,709,438
Ensembl chr12:40,695,520...40,709,462
JBrowse link
G Triap1 TP53 regulated inhibitor of apoptosis 1 increases expression ISO adefovir dipivoxil results in increased expression of TRIAP1 mRNA CTD PMID:25596134 NCBI chr12:46,987,404...46,989,906
Ensembl chr12:46,987,404...46,989,897
Ensembl chr12:46,987,404...46,989,897
JBrowse link
G Ube2o ubiquitin-conjugating enzyme E2O decreases expression ISO adefovir dipivoxil results in decreased expression of UBE2O mRNA CTD PMID:25596134 NCBI chr10:105,505,721...105,553,167
Ensembl chr10:105,506,955...105,552,986
JBrowse link
G Yars1 tyrosyl-tRNA synthetase 1 decreases expression ISO adefovir dipivoxil results in decreased expression of YARS1 mRNA CTD PMID:25596134 NCBI chr 5:147,375,350...147,403,578
Ensembl chr 5:147,375,350...147,403,571
JBrowse link
G Zmat3 zinc finger, matrin type 3 increases expression ISO adefovir dipivoxil results in increased expression of ZMAT3 mRNA CTD PMID:25596134 NCBI chr 2:118,715,229...118,746,109
Ensembl chr 2:118,721,334...118,745,766
JBrowse link
delavirdine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 decreases activity ISO Delavirdine results in decreased activity of CYP2C19 protein CTD PMID:11225565 NCBI chr 1:147,713,879...147,814,410
Ensembl chr 1:147,713,892...147,888,007
JBrowse link
didanosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin affects binding ISO Didanosine binds to ALB protein CTD PMID:15814459, PMID:16336266 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Hfe homeostatic iron regulator multiple interactions ISO HFE gene SNP affects the susceptibility to [Didanosine co-treated with Stavudine] CTD PMID:16847405 NCBI chr17:43,661,276...43,669,327
Ensembl chr17:43,661,222...43,669,985
JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II decreases expression
multiple interactions
ISO Didanosine results in decreased expression of COX2 mRNA
tenofovir promotes the reaction [Didanosine results in decreased expression of COX2 mRNA]
CTD PMID:16940060 NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689
JBrowse link
G Slc29a3 solute carrier family 29 member 3 affects transport ISO SLC29A3 protein affects the transport of Didanosine CTD PMID:19164483 NCBI chr20:30,289,527...30,327,343
Ensembl chr20:30,287,424...30,327,361
JBrowse link
efavirenz term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions
decreases activity
ISO efavirenz inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
efavirenz results in decreased activity of ABCB11 protein
CTD PMID:24014644 NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing decreases expression
decreases secretion
ISO efavirenz results in decreased expression of ADIPOQ mRNA
efavirenz results in decreased secretion of ADIPOQ protein
CTD PMID:21619898 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Alb albumin affects binding ISO efavirenz binds to ALB protein CTD PMID:15814459, PMID:16336266 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Bcl2l11 BCL2 like 11 increases response to substance
increases expression
ISO BCL2L11 protein results in increased susceptibility to efavirenz metabolite
efavirenz metabolite results in increased expression of BCL2L11 mRNA; efavirenz metabolite results in increased expression of BCL2L11 protein; efavirenz results in increased expression of BCL2L11 mRNA; efavirenz results in increased expression of BCL2L11 protein
CTD PMID:21958719 NCBI chr 3:120,726,906...120,764,192
Ensembl chr 3:120,726,906...120,764,192
JBrowse link
G Canx calnexin affects localization ISO efavirenz affects the localization of CANX protein CTD PMID:28940366 NCBI chr10:35,800,942...35,833,939
Ensembl chr10:35,800,942...35,833,861
JBrowse link
G Casp3 caspase 3 multiple interactions ISO efavirenz metabolite results in increased cleavage of and results in increased activity of CASP3 protein; efavirenz results in increased cleavage of and results in increased activity of CASP3 protein CTD PMID:21958719 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases secretion ISO efavirenz results in increased secretion of CCL2 protein CTD PMID:21619898 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha decreases expression ISO efavirenz results in decreased expression of CEBPA mRNA CTD PMID:21619898 NCBI chr 1:91,363,492...91,366,164
Ensembl chr 1:91,363,492...91,366,164
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 affects metabolic processing
decreases activity
multiple interactions
increases metabolic processing
ISO CYP2B6 gene polymorphism affects the metabolism of efavirenz; CYP2B6 protein affects the metabolism of efavirenz
efavirenz results in decreased activity of CYP2B6 protein
[efavirenz results in decreased activity of CYP2B6 protein] which results in decreased metabolism of Bupropion; [efavirenz results in increased activity of NR1I3 protein alternative form] which results in increased expression of CYP2B6 mRNA; [efavirenz results in increased activity of NR1I3 protein] which results in increased expression of CYP2B6 mRNA
CYP2B6 protein results in increased metabolism of efavirenz
CTD PMID:15622315, PMID:15769884, PMID:17041008, PMID:17559344, PMID:26599973 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 decreases activity ISO efavirenz results in decreased activity of CYP2C19 protein CTD PMID:11225565 NCBI chr 1:147,713,879...147,814,410
Ensembl chr 1:147,713,892...147,888,007
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO efavirenz results in increased expression of DDIT3 protein CTD PMID:28940366 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Dnm1l dynamin 1-like affects localization ISO efavirenz affects the localization of DNM1L protein modified form CTD PMID:28940366 NCBI chr11:88,830,968...88,882,271
Ensembl chr11:88,830,957...88,880,198
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 increases expression ISO efavirenz results in increased expression of EIF2AK3 protein modified form CTD PMID:28940366 NCBI chr 4:98,648,513...98,709,695
Ensembl chr 4:98,648,545...98,709,694
JBrowse link
G Fis1 fission, mitochondrial 1 increases expression ISO efavirenz results in increased expression of FIS1 mRNA CTD PMID:28940366 NCBI chr12:22,750,485...22,765,324
Ensembl chr12:22,750,485...22,765,308
JBrowse link
G Hgf hepatocyte growth factor increases secretion ISO efavirenz results in increased secretion of HGF protein CTD PMID:21619898 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 multiple interactions ISO efavirenz promotes the reaction [VDAC1 protein binds to HSPA9 protein] CTD PMID:28940366 NCBI chr18:27,731,072...27,749,235
Ensembl chr18:27,731,072...27,749,235
JBrowse link
G Il6 interleukin 6 increases secretion ISO efavirenz results in increased secretion of IL6 protein CTD PMID:21619898 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases phosphorylation ISO efavirenz metabolite results in increased phosphorylation of JUN protein; efavirenz results in increased phosphorylation of JUN protein CTD PMID:21958719 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Lep leptin decreases expression ISO efavirenz results in decreased expression of LEP mRNA CTD PMID:21619898 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Lonp1 lon peptidase 1, mitochondrial multiple interactions
increases expression
increases response to substance
ISO efavirenz results in increased expression of and affects the localization of LONP1 protein; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [efavirenz results in increased expression of LONP1 mRNA]
LONP1 protein results in increased susceptibility to efavirenz
CTD PMID:28940366 NCBI chr 9:10,428,853...10,441,180
Ensembl chr 9:10,428,853...10,441,177
JBrowse link
G Lpl lipoprotein lipase decreases expression ISO efavirenz results in decreased expression of LPL mRNA CTD PMID:21619898 NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 increases phosphorylation ISO efavirenz metabolite results in increased phosphorylation of MAP3K5 protein; efavirenz results in increased phosphorylation of MAP3K5 protein CTD PMID:21958719 NCBI chr 1:15,412,603...15,613,752
Ensembl chr 1:15,412,603...15,613,746
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions
increases phosphorylation
ISO Acetylcysteine inhibits the reaction [efavirenz metabolite results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [efavirenz results in increased phosphorylation of MAPK8 protein]
efavirenz metabolite results in increased phosphorylation of MAPK8 protein; efavirenz results in increased phosphorylation of MAPK8 protein
CTD PMID:21958719 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mfn2 mitofusin 2 increases expression ISO efavirenz results in increased expression of MFN2 mRNA CTD PMID:28940366 NCBI chr 5:164,684,244...164,715,414
Ensembl chr 5:164,684,509...164,714,145
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity EXP efavirenz results in increased activity of NR1I2 protein CTD PMID:27732639 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions
increases activity
ISO
EXP
[efavirenz results in increased activity of NR1I3 protein alternative form] which results in increased expression of CYP2B6 mRNA; [efavirenz results in increased activity of NR1I3 protein] which results in increased expression of CYP2B6 mRNA CTD PMID:17041008, PMID:27732639 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase increases expression ISO efavirenz results in increased expression of OPA1 mRNA CTD PMID:28940366 NCBI chr11:74,717,600...74,793,902
Ensembl chr11:74,720,254...74,793,803
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases expression ISO efavirenz results in decreased expression of PPARG mRNA CTD PMID:21619898 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Rmdn3 regulator of microtubule dynamics 3 increases expression ISO efavirenz results in increased expression of RMDN3 protein CTD PMID:28940366 NCBI chr 3:110,943,843...110,964,449
Ensembl chr 3:110,943,826...110,964,452
JBrowse link
G Serpine1 serpin family E member 1 increases secretion ISO efavirenz results in increased secretion of SERPINE1 protein CTD PMID:21619898 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Slc5a5 solute carrier family 5 member 5 multiple interactions ISO [efavirenz co-treated with TSHB protein] results in increased expression of SLC5A5 mRNA; [efavirenz co-treated with TSHB protein] results in increased expression of SLC5A5 protein CTD PMID:16030158 NCBI chr16:20,297,414...20,307,401
Ensembl chr16:20,297,414...20,307,400
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases expression ISO efavirenz results in decreased expression of SREBF1 mRNA CTD PMID:21619898 NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009
JBrowse link
G Tg thyroglobulin increases expression ISO efavirenz results in increased expression of TG mRNA; efavirenz results in increased expression of TG protein CTD PMID:16030158 NCBI chr 7:107,467,260...107,652,897
Ensembl chr 7:107,467,260...107,652,899
JBrowse link
G Tpo thyroid peroxidase increases expression ISO efavirenz results in increased expression of TPO mRNA; efavirenz results in increased expression of TPO protein CTD PMID:16030158 NCBI chr 6:49,020,918...49,089,855
Ensembl chr 6:49,021,044...49,089,855
JBrowse link
G Tshb thyroid stimulating hormone subunit beta multiple interactions ISO [efavirenz co-treated with TSHB protein] results in increased expression of SLC5A5 mRNA; [efavirenz co-treated with TSHB protein] results in increased expression of SLC5A5 protein; efavirenz promotes the reaction [TSHB protein affects the abundance of Iodine]; sodium perchlorate inhibits the reaction [efavirenz promotes the reaction [TSHB protein affects the abundance of Iodine]] CTD PMID:16030158 NCBI chr 2:205,207,799...205,215,199
Ensembl chr 2:205,207,799...205,212,681
JBrowse link
G Tshr thyroid stimulating hormone receptor increases expression ISO efavirenz results in increased expression of TSHR mRNA CTD PMID:16030158 NCBI chr 6:115,170,290...115,306,871
Ensembl chr 6:115,170,865...115,306,871
JBrowse link
G Vdac1 voltage-dependent anion channel 1 multiple interactions ISO efavirenz promotes the reaction [VDAC1 protein binds to HSPA9 protein] CTD PMID:28940366 NCBI chr10:37,724,915...37,752,827
Ensembl chr10:37,724,915...37,752,826
JBrowse link
emtricitabine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin affects binding ISO Emtricitabine binds to ALB protein CTD PMID:15814459, PMID:16336266 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO [Emtricitabine co-treated with Tenofovir] results in increased expression of CDKN1A protein CTD PMID:31545371 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Dck deoxycytidine kinase multiple interactions
affects binding
ISO DCK protein results in increased phosphorylation of and results in increased activity of Emtricitabine
Emtricitabine binds to DCK protein
CTD PMID:17530837 NCBI chr14:20,935,442...20,952,939
Ensembl chr14:20,935,369...20,953,095
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase decreases expression
multiple interactions
ISO Emtricitabine results in decreased expression of PRKN protein
[Emtricitabine co-treated with Tenofovir] results in decreased expression of PRKN protein
CTD PMID:31545371 NCBI chr 1:48,880,015...50,069,998 JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO [Emtricitabine co-treated with Tenofovir] results in increased expression of TP53 protein CTD PMID:31545371 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
lamivudine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acadsb acyl-CoA dehydrogenase, short/branched chain multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ACADSB mRNA CTD PMID:18313992 NCBI chr 1:201,981,362...202,022,771
Ensembl chr 1:201,981,357...202,021,008
JBrowse link
G Acsl6 acyl-CoA synthetase long-chain family member 6 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of ACSL6 mRNA CTD PMID:18313992 NCBI chr10:39,654,771...39,717,592
Ensembl chr10:39,655,455...39,719,312
JBrowse link
G Acta2 actin alpha 2, smooth muscle decreases expression ISO Lamivudine results in decreased expression of ACTA2 protein CTD PMID:11738102 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of ADIPOQ mRNA CTD PMID:16931933 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Aebp1 AE binding protein 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of AEBP1 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of AEBP1 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of AEBP1 mRNA CTD PMID:16931933 NCBI chr14:86,101,253...86,111,323
Ensembl chr14:86,101,277...86,111,306
JBrowse link
G Afap1 actin filament associated protein 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of AFAP1 mRNA CTD PMID:15784690 NCBI chr14:79,923,132...80,035,096
Ensembl chr14:79,919,717...79,988,110
JBrowse link
G Alb albumin affects binding ISO Lamivudine binds to ALB protein CTD PMID:15814459, PMID:16336266 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of ALOX5AP mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of ALOX5AP mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of ALOX5AP mRNA CTD PMID:16931933 NCBI chr12:6,854,930...6,879,112
Ensembl chr12:6,854,920...6,879,154
JBrowse link
G Aqp9 aquaporin 9 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of AQP9 mRNA CTD PMID:18313992 NCBI chr 8:77,559,621...77,599,781
Ensembl chr 8:77,559,624...77,599,781
JBrowse link
G Arpp21 cAMP regulated phosphoprotein 21 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of ARPP21 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of ARPP21 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of ARPP21 mRNA CTD PMID:16931933 NCBI chr 8:120,323,895...120,492,790
Ensembl chr 8:120,323,897...120,446,507
JBrowse link
G Asic2 acid sensing ion channel subunit 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of ASIC2 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of ASIC2 mRNA CTD PMID:16931933 NCBI chr10:68,247,800...69,347,223
Ensembl chr10:68,248,655...68,517,564
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ASNS mRNA CTD PMID:15784690 NCBI chr 4:33,742,876...33,761,106
Ensembl chr 4:33,743,364...33,761,163
JBrowse link
G Ass1 argininosuccinate synthase 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ASS1 mRNA CTD PMID:15784690 NCBI chr 3:10,327,411...10,375,847
Ensembl chr 3:10,327,414...10,375,826
JBrowse link
G Atf3 activating transcription factor 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ATF3 mRNA CTD PMID:15784690 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of ATP2A2 mRNA CTD PMID:11706060 NCBI chr12:39,553,903...39,603,326
Ensembl chr12:39,553,903...39,603,326
JBrowse link
G Atp5f1c ATP synthase F1 subunit gamma multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ATP5C1 mRNA CTD PMID:18313992 NCBI chr17:72,209,321...72,231,562
Ensembl chr17:72,209,373...72,394,271
JBrowse link
G Atp5mc3 ATP synthase membrane subunit c locus 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of ATP5G3 mRNA CTD PMID:18313992 NCBI chr 3:60,811,218...60,813,903
Ensembl chr 3:60,811,210...60,813,869
JBrowse link
G Atp5mf ATP synthase membrane subunit f multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ATP5J2 mRNA CTD PMID:18313992 NCBI chr12:11,191,799...11,198,369
Ensembl chr12:11,191,812...11,198,369
JBrowse link
G Atp5pd ATP synthase peripheral stalk subunit d multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ATP5H mRNA CTD PMID:18313992 NCBI chr10:103,967,340...103,972,552
Ensembl chr10:103,967,312...103,972,668
JBrowse link
G Atp5pf ATP synthase peripheral stalk subunit F6 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ATP5J mRNA CTD PMID:18313992 NCBI chr11:24,286,806...24,294,419
Ensembl chr11:24,286,787...24,294,179
JBrowse link
G Atp5po ATP synthase peripheral stalk subunit OSCP multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of ATP5O mRNA CTD PMID:18313992 NCBI chr11:32,081,606...32,087,918
Ensembl chr11:32,081,574...32,088,002
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of BCL2 mRNA CTD PMID:18313992 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bnip3l BCL2 interacting protein 3 like increases expression ISO Lamivudine results in increased expression of BNIP3L protein CTD PMID:23640862 NCBI chr15:43,643,897...43,667,123
Ensembl chr15:43,643,897...43,667,029
JBrowse link
G C1r complement C1r multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of C1R mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of C1R mRNA CTD PMID:16931933 NCBI chr 4:157,126,060...157,136,825
Ensembl chr 4:157,125,998...157,136,829
JBrowse link
G C3ar1 complement C3a receptor 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of C3AR1 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of C3AR1 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of C3AR1 mRNA CTD PMID:16931933 NCBI chr 4:155,681,767...155,691,240
Ensembl chr 4:155,684,029...155,690,869
JBrowse link
G Cars cysteinyl-tRNA synthetase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of CARS1 mRNA CTD PMID:15784690 NCBI chr 1:216,759,367...216,801,652
Ensembl chr 1:216,759,366...216,801,656
JBrowse link
G Ccna2 cyclin A2 multiple interactions
decreases expression
ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CCNA2 mRNA
Lamivudine results in decreased expression of CCNA2 mRNA
CTD PMID:15784690 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214
JBrowse link
G Ccnc cyclin C multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CCNC mRNA CTD PMID:15784690 NCBI chr 5:35,865,598...35,883,732
Ensembl chr 5:35,865,605...35,883,706
JBrowse link
G Ccnd1 cyclin D1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of CCND1 mRNA CTD PMID:15784690 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccnd2 cyclin D2 decreases expression
multiple interactions
ISO Lamivudine results in decreased expression of CCND2 mRNA
[Zidovudine co-treated with Lamivudine] results in decreased expression of CCND2 mRNA
CTD PMID:15784690 NCBI chr 4:159,674,885...159,697,207
Ensembl chr 4:159,674,885...159,697,207
JBrowse link
G Ccne2 cyclin E2 multiple interactions
decreases expression
ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CCNE2 mRNA
Lamivudine results in decreased expression of CCNE2 mRNA
CTD PMID:15784690 NCBI chr 5:24,434,077...24,446,406
Ensembl chr 5:24,434,872...24,446,406
JBrowse link
G Cd36 CD36 molecule multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of CD36 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of CD36 mRNA CTD PMID:16931933 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cd44 CD44 molecule (Indian blood group) multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of CD44 mRNA CTD PMID:15784690 NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658
JBrowse link
G Cd83 CD83 molecule multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CD83 mRNA CTD PMID:15784690 NCBI chr17:24,416,651...24,435,790
Ensembl chr17:24,416,651...24,435,790
JBrowse link
G Cdk7 cyclin-dependent kinase 7 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of CDK7 mRNA CTD PMID:15784690 NCBI chr 2:30,710,642...30,735,522
Ensembl chr 2:30,710,643...30,735,514
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression
multiple interactions
ISO Lamivudine results in decreased expression of CDKN1A mRNA
[Zidovudine co-treated with Lamivudine] results in decreased expression of CDKN1A mRNA
CTD PMID:15784690 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CDKN1B mRNA CTD PMID:15784690 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CDKN1C mRNA CTD PMID:15784690 NCBI chr 1:216,661,067...216,663,791
Ensembl chr 1:216,661,080...216,663,721
JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CDKN2C mRNA CTD PMID:15784690 NCBI chr 5:129,347,731...129,352,886
Ensembl chr 5:129,347,732...129,352,886
JBrowse link
G Cfd complement factor D multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of CFD mRNA CTD PMID:16931933 NCBI chr 7:12,634,216...12,635,939
Ensembl chr 7:12,634,216...12,635,943
JBrowse link
G Cidec cell death-inducing DFFA-like effector c multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of CIDEC mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of CIDEC mRNA CTD PMID:16931933 NCBI chr 4:145,377,482...145,390,497
Ensembl chr 4:145,377,431...145,390,497
JBrowse link
G Clcn3 chloride voltage-gated channel 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of CLCN3 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of CLCN3 mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of CLCN3 mRNA CTD PMID:16931933 NCBI chr16:32,448,821...32,520,649
Ensembl chr16:32,449,116...32,519,148
JBrowse link
G Col3a1 collagen type III alpha 1 chain decreases expression ISO Lamivudine results in decreased expression of COL3A1 protein CTD PMID:11738102 NCBI chr 9:52,023,295...52,059,221
Ensembl chr 9:52,023,295...52,059,217
JBrowse link
G Comt catechol-O-methyltransferase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of COMT mRNA CTD PMID:15784690 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Cox5a cytochrome c oxidase subunit 5A multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of COX5A mRNA CTD PMID:18313992 NCBI chr 8:62,298,358...62,309,765
Ensembl chr 8:62,298,358...62,309,765
JBrowse link
G Cox5b cytochrome c oxidase subunit 5B multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of COX5B mRNA CTD PMID:18313992 NCBI chr 9:43,259,706...43,262,039
Ensembl chr 9:43,259,709...43,262,040
JBrowse link
G Cox6a1 cytochrome c oxidase subunit 6A1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of COX6A1 mRNA CTD PMID:18313992 NCBI chr12:47,024,442...47,027,495
Ensembl chr12:47,024,442...47,027,495
JBrowse link
G Cox6c cytochrome c oxidase subunit 6C multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of COX6C mRNA CTD PMID:18313992 NCBI chr 7:74,723,177...74,735,650
Ensembl chr 7:74,723,179...74,735,650
JBrowse link
G Cox7c cytochrome c oxidase subunit 7C multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of COX7C mRNA CTD PMID:18313992 NCBI chr 2:14,699,878...14,701,903
Ensembl chr 2:14,699,882...14,701,903
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of CPT1A mRNA CTD PMID:18313992 NCBI chr 1:218,568,157...218,629,679
Ensembl chr 1:218,569,510...218,629,678
JBrowse link
G Crat carnitine O-acetyltransferase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of CRAT mRNA CTD PMID:18313992 NCBI chr 3:8,967,984...8,981,959
Ensembl chr 3:8,968,417...8,981,362
JBrowse link
G Cul7 cullin 7 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CUL7 mRNA CTD PMID:18313992 NCBI chr 9:16,629,491...16,643,527
Ensembl chr 9:16,629,401...16,643,182
JBrowse link
G Cyb5a cytochrome b5 type A multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of CYB5A mRNA CTD PMID:18313992 NCBI chr18:81,694,818...81,726,821
Ensembl chr18:81,694,808...81,726,821
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CYP11A1 mRNA CTD PMID:18313992 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Dck deoxycytidine kinase multiple interactions ISO DCK protein results in increased phosphorylation of and results in increased activity of Lamivudine CTD PMID:17530837 NCBI chr14:20,935,442...20,952,939
Ensembl chr14:20,935,369...20,953,095
JBrowse link
G Dcn decorin multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of DCN mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of DCN mRNA CTD PMID:16931933 NCBI chr 7:38,742,250...38,782,282
Ensembl chr 7:38,742,051...38,782,323
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions
ISO Lamivudine results in increased expression of DDIT3 mRNA
[Zidovudine co-treated with Lamivudine] results in increased expression of DDIT3 mRNA
CTD PMID:15784690 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Dhfr dihydrofolate reductase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of DHFR mRNA CTD PMID:15784690 NCBI chr 2:21,931,887...21,958,927
Ensembl chr 2:21,931,493...21,962,453
JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of DIABLO mRNA CTD PMID:18313992 NCBI chr12:38,490,230...38,503,344
Ensembl chr12:38,490,230...38,503,330
JBrowse link
G Dlst dihydrolipoamide S-succinyltransferase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of DLST mRNA CTD PMID:18313992 NCBI chr 6:108,936,534...108,961,322
Ensembl chr 6:108,936,664...108,959,803
JBrowse link
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of DNAJA3 mRNA CTD PMID:18313992 NCBI chr10:11,059,701...11,085,186
Ensembl chr10:11,060,313...11,085,210
JBrowse link
G Dusp3 dual specificity phosphatase 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of DUSP3 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of DUSP3 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of DUSP3 mRNA CTD PMID:16931933 NCBI chr10:89,904,578...89,918,296
Ensembl chr10:89,904,560...89,918,427
JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ECHS1 mRNA CTD PMID:18313992 NCBI chr 1:212,570,213...212,579,040
Ensembl chr 1:212,570,195...212,579,057
JBrowse link
G Eci1 enoyl-CoA delta isomerase 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of ECI1 mRNA CTD PMID:18313992 NCBI chr10:13,797,573...13,810,918
Ensembl chr10:13,797,562...13,810,913
JBrowse link
G Edn1 endothelin 1 multiple interactions
increases secretion
ISO coenzyme Q10 inhibits the reaction [Lamivudine results in increased secretion of EDN1 protein] CTD PMID:23640862 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of EIF4EBP1 mRNA CTD PMID:15784690 NCBI chr16:68,954,860...68,968,248
Ensembl chr16:68,954,875...68,968,248
JBrowse link
G Elovl3 ELOVL fatty acid elongase 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of ELOVL3 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of ELOVL3 mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of ELOVL3 mRNA CTD PMID:16931933 NCBI chr 1:265,883,353...265,887,181
Ensembl chr 1:265,883,355...265,887,226
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of ESR2 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of ESR2 mRNA CTD PMID:16931933 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Etv6 ETS variant transcription factor 6 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of ETV6 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of ETV6 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of ETV6 mRNA CTD PMID:16931933 NCBI chr 4:167,754,684...167,992,370
Ensembl chr 4:167,754,525...167,992,168
JBrowse link
G Fads2 fatty acid desaturase 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of FADS2 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of FADS2 mRNA CTD PMID:16931933 NCBI chr 1:225,906,582...226,152,568
Ensembl chr 1:226,114,413...226,152,524
JBrowse link
G Faim Fas apoptotic inhibitory molecule multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of FAIM mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of FAIM mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of FAIM mRNA CTD PMID:16931933 NCBI chr 8:107,225,119...107,247,228
Ensembl chr 8:107,225,212...107,241,224
Ensembl chr 8:107,225,212...107,241,224
JBrowse link
G Fasn fatty acid synthase multiple interactions ISO [Stavudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of FASN mRNA; [Stavudine co-treated with Lamivudine] results in increased expression of FASN mRNA; [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of FASN mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of FASN mRNA CTD PMID:11741158 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Fdxr ferredoxin reductase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of FDXR mRNA CTD PMID:18313992 NCBI chr10:103,817,724...103,826,413
Ensembl chr10:103,817,704...103,826,448
JBrowse link
G Fh fumarate hydratase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of FH1 mRNA CTD PMID:18313992 NCBI chr13:93,651,486...93,677,371
Ensembl chr13:93,651,484...93,677,377
JBrowse link
G G0s2 G0/G1switch 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of G0S2 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of G0S2 mRNA CTD PMID:16931933 NCBI chr13:112,004,140...112,005,052
Ensembl chr13:112,004,140...112,005,052
JBrowse link
G G6pc glucose-6-phosphatase, catalytic subunit multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of G6PC mRNA CTD PMID:16931933 NCBI chr10:89,286,009...89,296,213
Ensembl chr10:89,285,855...89,296,213
JBrowse link
G Ganc glucosidase, alpha; neutral C multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of GANC mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of GANC mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of GANC mRNA CTD PMID:16931933 NCBI chr 3:112,173,907...112,226,886
Ensembl chr 3:112,173,907...112,226,023
JBrowse link
G Gars glycyl-tRNA synthetase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of GARS1 mRNA CTD PMID:15784690 NCBI chr 4:85,235,122...85,276,085
Ensembl chr 4:85,235,172...85,276,044
JBrowse link
G Gas1 growth arrest-specific 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of GAS1 mRNA CTD PMID:15784690 NCBI chr17:4,846,116...4,849,350
Ensembl chr17:4,846,789...4,847,940
JBrowse link
G Grhl2 grainyhead-like transcription factor 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of GRHL2 mRNA CTD PMID:16931933 NCBI chr 7:76,058,623...76,197,360
Ensembl chr 7:76,059,386...76,197,856
JBrowse link
G Gucy1b1 guanylate cyclase 1 soluble subunit beta 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of GUCY1B1 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of GUCY1B1 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of GUCY1B1 mRNA CTD PMID:16931933 NCBI chr 2:180,976,939...181,026,001
Ensembl chr 2:180,976,939...181,026,024
JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of HADH mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of HADH mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of HADH mRNA CTD PMID:16931933 NCBI chr 2:236,353,445...236,395,067
Ensembl chr 2:236,353,445...236,395,067
JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of HADHA mRNA CTD PMID:18313992 NCBI chr 6:27,589,840...27,628,921
Ensembl chr 6:27,589,657...27,629,175
JBrowse link
G Hax1 HCLS1 associated protein X-1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of HAX1 mRNA CTD PMID:15784690 NCBI chr 2:189,330,900...189,333,305
Ensembl chr 2:189,330,902...189,333,322
JBrowse link
G Hcn1 hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of HCN1 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of HCN1 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of HCN1 mRNA CTD PMID:16931933 NCBI chr 2:50,099,576...50,499,799
Ensembl chr 2:50,099,576...50,499,799
JBrowse link
G Hist1h4a histone cluster 1 H4 family member A multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of H4C9 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of H4C9 mRNA CTD PMID:16931933 NCBI chr17:43,617,161...43,617,705 JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of HMGCS2 mRNA CTD PMID:18313992 NCBI chr 2:200,452,623...200,480,785
Ensembl chr 2:200,452,624...200,479,423
JBrowse link
G Hrk harakiri, BCL2 interacting protein multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of HRK mRNA CTD PMID:16931933 NCBI chr12:44,008,879...44,029,211 JBrowse link
G Hsd3b3 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of HSD3B3 mRNA CTD PMID:18313992 NCBI chr 2:200,756,557...200,762,492
Ensembl chr 2:200,585,748...200,762,492
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of IDH2 mRNA CTD PMID:18313992 NCBI chr 1:141,874,354...141,893,674
Ensembl chr 1:141,866,283...141,893,705
JBrowse link
G Idh3a isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of IDH3A mRNA CTD PMID:18313992 NCBI chr 8:59,164,601...59,183,899
Ensembl chr 8:59,164,572...59,183,908
JBrowse link
G Idh3g isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of IDH3G mRNA CTD PMID:18313992 NCBI chr  X:156,999,803...157,008,735
Ensembl chr  X:156,999,826...157,008,733
JBrowse link
G Ifng interferon gamma increases expression ISO Lamivudine results in increased expression of IFNG protein CTD PMID:16250037 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Ikzf4 IKAROS family zinc finger 4 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of IKZF4 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of IKZF4 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of IKZF4 mRNA CTD PMID:16931933 NCBI chr 7:3,061,422...3,098,142
Ensembl chr 7:3,061,469...3,074,359
JBrowse link
G Il27ra interleukin 27 receptor subunit alpha multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of IL27RA mRNA CTD PMID:15784690 NCBI chr19:25,151,835...25,163,995
Ensembl chr19:25,149,897...25,164,086
JBrowse link
G Inpp5e inositol polyphosphate-5-phosphatase E multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of INPP5E mRNA CTD PMID:18313992 NCBI chr 3:3,843,307...3,856,154
Ensembl chr 3:3,843,307...3,855,981
JBrowse link
G Kcng1 potassium voltage-gated channel modifier subfamily G member 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of KCNG1 mRNA CTD PMID:15784690 NCBI chr 3:165,020,230...165,040,966
Ensembl chr 3:165,020,230...165,039,707
JBrowse link
G Kifc2 kinesin family member C2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of KIFC2 mRNA CTD PMID:16931933 NCBI chr 7:117,722,732...117,730,702
Ensembl chr 7:117,723,263...117,730,702
JBrowse link
G Klf4 Kruppel like factor 4 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of KLF4 mRNA CTD PMID:15784690 NCBI chr 5:72,283,311...72,287,669
Ensembl chr 5:72,283,313...72,287,669
JBrowse link
G Klhl28 kelch-like family member 28 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of KLHL28 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of KLHL28 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of KLHL28 mRNA CTD PMID:16931933 NCBI chr 6:86,680,826...86,713,370
Ensembl chr 6:86,684,413...86,713,370
JBrowse link
G Krt7 keratin 7 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of KRT7 mRNA CTD PMID:15784690 NCBI chr 7:143,059,731...143,075,907
Ensembl chr 7:143,059,764...143,075,907
JBrowse link
G Kynu kynureninase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of KYNU mRNA CTD PMID:15784690 NCBI chr 3:28,416,926...28,566,939
Ensembl chr 3:28,416,954...28,566,928
JBrowse link
G Lamb3 laminin subunit beta 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of LAMB3 mRNA CTD PMID:15784690 NCBI chr13:112,031,614...112,073,187
Ensembl chr13:112,031,594...112,073,186
JBrowse link
G Lamc2 laminin subunit gamma 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of LAMC2 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of LAMC2 mRNA CTD PMID:16931933 NCBI chr13:70,566,643...70,632,126
Ensembl chr13:70,566,643...70,626,252
JBrowse link
G Lef1 lymphoid enhancer binding factor 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of LEF1 mRNA CTD PMID:16931933 NCBI chr 2:236,232,115...236,345,061
Ensembl chr 2:236,233,239...236,345,056
JBrowse link
G Lep leptin multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of LEP mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of LEP mRNA CTD PMID:16931933 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Lpl lipoprotein lipase decreases expression
multiple interactions
ISO Lamivudine results in decreased expression of LPL mRNA
[Stavudine co-treated with Lamivudine co-treated with Indinavir] affects the expression of LPL mRNA; [Stavudine co-treated with Lamivudine co-treated with Nelfinavir] results in decreased expression of LPL mRNA; [Stavudine co-treated with Lamivudine] affects the expression of LPL mRNA; [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of LPL mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of LPL mRNA
CTD PMID:11741158 NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496
JBrowse link
G Mars1 methionyl-tRNA synthetase 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of MARS1 mRNA CTD PMID:15784690 NCBI chr 7:70,585,011...70,602,425
Ensembl chr 7:70,585,013...70,602,310
JBrowse link
G Me1 malic enzyme 1 multiple interactions
increases expression
ISO [Stavudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of ME1 mRNA; [Stavudine co-treated with Lamivudine co-treated with Nelfinavir] results in decreased expression of ME1 mRNA; [Stavudine co-treated with Lamivudine] results in increased expression of ME1 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of ME1 mRNA; [Zidovudine co-treated with Lamivudine] affects the expression of ME1 mRNA
Lamivudine results in increased expression of ME1 mRNA
CTD PMID:11741158 NCBI chr 8:94,256,830...94,368,834
Ensembl chr 8:94,256,839...94,368,834
JBrowse link
G Mfn1 mitofusin 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of MFN1 mRNA CTD PMID:18313992 NCBI chr 2:118,929,738...118,971,689
Ensembl chr 2:118,929,738...118,973,698
JBrowse link
G Mfn2 mitofusin 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of MFN2 mRNA CTD PMID:18313992 NCBI chr 5:164,684,244...164,715,414
Ensembl chr 5:164,684,509...164,714,145
JBrowse link
G Mgat4c MGAT4 family, member C multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of MGAT4C mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of MGAT4C mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of MGAT4C mRNA CTD PMID:16931933 NCBI chr 7:43,249,369...44,024,278
Ensembl chr 7:44,009,069...44,024,456
JBrowse link
G Mmp1 matrix metallopeptidase 1 increases expression ISO Lamivudine results in increased expression of MMP1 protein CTD PMID:15309715 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Mrap melanocortin 2 receptor accessory protein multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of MRAP mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of MRAP mRNA CTD PMID:16931933 NCBI chr11:30,904,733...30,915,225
Ensembl chr11:30,904,733...30,915,225
JBrowse link
G Mt-co1 mitochondrially encoded cytochrome c oxidase I multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of COX1 mRNA CTD PMID:17526437, PMID:18313992 NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867
JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of COX2 mRNA CTD PMID:18313992 NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689
JBrowse link
G Mt-co3 mitochondrially encoded cytochrome c oxidase III multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of COX3 mRNA CTD PMID:17526437, PMID:18313992 NCBI chr MT:8,599...9,382
Ensembl chr MT:8,599...9,382
JBrowse link
G Mt-nd2 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of ND2 mRNA CTD PMID:18313992 NCBI chr MT:3,904...4,942
Ensembl chr MT:3,904...4,942
JBrowse link
G Mt-nd5 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of ND5 mRNA CTD PMID:17526437, PMID:18313992 NCBI chr MT:11,736...13,565
Ensembl chr MT:11,736...13,565
JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of MTHFD2 mRNA CTD PMID:15784690 NCBI chr 4:115,004,433...115,015,965
Ensembl chr 4:115,004,448...115,015,965
JBrowse link
G Myod1 myogenic differentiation 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of MYOD1 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of MYOD1 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of MYOD1 mRNA CTD PMID:16931933 NCBI chr 1:102,396,538...102,399,248
Ensembl chr 1:102,396,538...102,399,248
JBrowse link
G Nap1l5 nucleosome assembly protein 1-like 5 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of NAP1L5 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of NAP1L5 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of NAP1L5 mRNA CTD PMID:16931933 NCBI chr 4:89,149,314...89,152,511
Ensembl chr 4:89,149,317...89,151,184
JBrowse link
G Ndufa4 NDUFA4, mitochondrial complex associated multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of NDUFA4 mRNA CTD PMID:18313992 NCBI chr 4:38,233,680...38,240,848
Ensembl chr 4:38,233,680...38,240,848
JBrowse link
G Ndufab1 NADH:ubiquinone oxidoreductase subunit AB1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of NDUFAB1 mRNA CTD PMID:18313992 NCBI chr 1:192,044,209...192,057,644
Ensembl chr 1:192,044,216...192,057,612
JBrowse link
G Ndufaf1 NADH:ubiquinone oxidoreductase complex assembly factor 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of NDUFAF1 mRNA CTD PMID:18313992 NCBI chr 3:111,458,227...111,469,239
Ensembl chr 3:111,458,572...111,469,518
JBrowse link
G Ndufb3 NADH:ubiquinone oxidoreductase subunit B3 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of NDUFB3 mRNA CTD PMID:18313992 NCBI chr 9:65,478,496...65,488,708
Ensembl chr 9:65,478,496...65,488,702
JBrowse link
G Ndufb5 NADH:ubiquinone oxidoreductase subunit B5 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of NDUFB5 mRNA CTD PMID:18313992 NCBI chr 2:119,139,717...119,153,753
Ensembl chr 2:119,139,717...119,153,753
JBrowse link
G Ndufb9 NADH:ubiquinone oxidoreductase subunit B9 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of NDUFB9 mRNA CTD PMID:18313992 NCBI chr 7:98,813,062...98,819,408
Ensembl chr 7:98,813,040...98,819,452
JBrowse link
G Ndufc1 NADH:ubiquinone oxidoreductase subunit C1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of NDUFC1 mRNA CTD PMID:18313992 NCBI chr 2:140,460,749...140,464,588
Ensembl chr 2:140,462,900...140,464,607
JBrowse link
G Ndufs1 NADH:ubiquinone oxidoreductase core subunit S1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of NDUFS1 mRNA CTD PMID:18313992 NCBI chr 9:69,919,863...69,953,182
Ensembl chr 9:69,919,867...69,953,182
JBrowse link
G Niban1 niban apoptosis regulator 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of NIBAN1 mRNA CTD PMID:15784690 NCBI chr13:68,949,665...69,101,600
Ensembl chr13:68,949,665...69,101,588
JBrowse link
G Noct nocturnin multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of NOCT mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of NOCT mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of NOCT mRNA CTD PMID:16931933 NCBI chr 2:140,286,661...140,306,869
Ensembl chr 2:140,286,661...140,306,869
JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions
decreases phosphorylation
ISO coenzyme Q10 inhibits the reaction [Lamivudine results in decreased phosphorylation of NOS3 protein] CTD PMID:23640862 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Nppa natriuretic peptide A multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of NPPA mRNA CTD PMID:11706060 NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705
JBrowse link
G Nup210 nucleoporin 210 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of NUP210 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of NUP210 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of NUP210 mRNA CTD PMID:16931933 NCBI chr 4:122,643,952...122,741,322
Ensembl chr 4:122,644,135...122,741,110
JBrowse link
G Nxnl2 nucleoredoxin-like 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of NXNL2 mRNA CTD PMID:16931933 NCBI chr17:14,053,896...14,058,642
Ensembl chr17:14,053,896...14,058,642
JBrowse link
G Oaz3 ornithine decarboxylase antizyme 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of OAZ3 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of OAZ3 mRNA CTD PMID:16931933 NCBI chr 2:195,675,925...195,678,859
Ensembl chr 2:195,676,048...195,678,848
JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of OGT mRNA CTD PMID:15784690 NCBI chr  X:71,540,870...71,585,906
Ensembl chr  X:71,528,988...71,585,908
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of OPA1 mRNA CTD PMID:18313992 NCBI chr11:74,717,600...74,793,902
Ensembl chr11:74,720,254...74,793,803
JBrowse link
G Oprl1 opioid related nociceptin receptor 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of OPRL1 mRNA CTD PMID:16931933 NCBI chr 3:177,223,779...177,231,663
Ensembl chr 3:177,225,737...177,231,663
JBrowse link
G Pcdh15 protocadherin related 15 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of PCDH15 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of PCDH15 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of PCDH15 mRNA CTD PMID:16931933 NCBI chr20:14,952,213...15,334,745
Ensembl chr20:14,952,213...15,334,745
JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of PCK2 mRNA CTD PMID:15784690 NCBI chr15:34,216,735...34,224,357
Ensembl chr15:34,216,833...34,224,193
JBrowse link
G Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of PFKFB3 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of PFKFB3 mRNA CTD PMID:16931933 NCBI chr17:70,632,778...70,713,736
Ensembl chr17:70,684,134...70,713,726
JBrowse link
G Pgap6 post-glycosylphosphatidylinositol attachment to proteins 6 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of PGAP6 mRNA CTD PMID:16931933 NCBI chr10:15,484,952...15,495,380
Ensembl chr10:15,484,795...15,495,377
JBrowse link
G Phf6 PHD finger protein 6 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of PHF6 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of PHF6 mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of PHF6 mRNA CTD PMID:16931933 NCBI chr  X:158,698,353...158,739,855
Ensembl chr  X:158,698,356...158,739,838
Ensembl chr  X:158,698,356...158,739,838
JBrowse link
G Pidd1 p53-induced death domain protein 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of PIDD1 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of PIDD1 mRNA CTD PMID:16931933 NCBI chr 1:214,418,751...214,423,959
Ensembl chr 1:214,419,240...214,423,881
JBrowse link
G Piwil2 piwi-like RNA-mediated gene silencing 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of PIWIL2 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of PIWIL2 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of PIWIL2 mRNA CTD PMID:16931933 NCBI chr15:52,037,693...52,116,277
Ensembl chr15:52,037,693...52,116,001
JBrowse link
G Porcn porcupine O-acyltransferase multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of PPN mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of PPN mRNA CTD PMID:16931933 NCBI chr  X:15,035,569...15,048,440
Ensembl chr  X:15,035,569...15,048,440
JBrowse link
G Pou5f1 POU class 5 homeobox 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of POU5F1 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of POU5F1 mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of POU5F1 mRNA CTD PMID:16931933 NCBI chr20:3,747,231...3,751,994
Ensembl chr20:3,747,221...3,751,994
JBrowse link
G Prdm1 PR/SET domain 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of PRDM1 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of PRDM1 mRNA CTD PMID:16931933 NCBI chr20:49,464,921...49,556,623
Ensembl chr20:49,464,919...49,556,518
JBrowse link
G Psat1 phosphoserine aminotransferase 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of PSAT1 mRNA CTD PMID:15784690 NCBI chr 1:233,124,089...233,145,941
Ensembl chr 1:233,124,092...233,145,941
JBrowse link
G Rabepk Rab9 effector protein with kelch motifs multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of RABEPK mRNA CTD PMID:15784690 NCBI chr 3:13,845,352...13,865,843
Ensembl chr 3:13,845,361...13,865,843
JBrowse link
G Rbl1 RB transcriptional corepressor like 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of RBL1 mRNA CTD PMID:15784690 NCBI chr 3:153,263,692...153,321,351
Ensembl chr 3:153,263,692...153,321,352
JBrowse link
G Rbl2 RB transcriptional corepressor like 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of RBL2 mRNA CTD PMID:15784690 NCBI chr19:17,300,088...17,346,865
Ensembl chr19:17,300,089...17,346,808
JBrowse link
G Reep6 receptor accessory protein 6 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of REEP6 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of REEP6 mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of REEP6 mRNA CTD PMID:16931933 NCBI chr 7:12,240,059...12,246,814
Ensembl chr 7:12,240,060...12,246,729
JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of RIPK2 mRNA CTD PMID:15784690 NCBI chr 5:29,838,713...29,870,390
Ensembl chr 5:29,838,747...29,870,735
JBrowse link
G Rnf151 ring finger protein 151 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of RNF151 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of RNF151 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of RNF151 mRNA CTD PMID:16931933 NCBI chr10:14,083,538...14,088,011
Ensembl chr10:14,083,538...14,085,855
JBrowse link
G Rpain RPA interacting protein multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of RPAIN mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of RPAIN mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of RPAIN mRNA CTD PMID:16931933 NCBI chr10:57,606,287...57,613,834
Ensembl chr10:57,606,650...57,613,747
JBrowse link
G S100a8 S100 calcium binding protein A8 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of S100A8 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of S100A8 mRNA CTD PMID:16931933 NCBI chr 2:190,073,239...190,074,333
Ensembl chr 2:190,073,815...190,074,354
JBrowse link
G Sdhb succinate dehydrogenase complex iron sulfur subunit B multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of SDHB mRNA CTD PMID:18313992 NCBI chr 5:159,484,378...159,505,063
Ensembl chr 5:159,484,370...159,505,064
JBrowse link
G Serinc1 serine incorporator 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of SERINC1 mRNA CTD PMID:16931933 NCBI chr20:38,966,016...38,985,056
Ensembl chr20:38,967,238...38,985,036
JBrowse link
G Sfxn1 sideroflexin 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SFXN1 mRNA CTD PMID:18313992 NCBI chr17:11,046,588...11,082,219
Ensembl chr17:11,045,761...11,082,047
JBrowse link
G Sfxn2 sideroflexin 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SFXN2 mRNA CTD PMID:18313992 NCBI chr 1:266,333,440...266,345,736
Ensembl chr 1:266,333,440...266,345,697
JBrowse link
G Sfxn4 sideroflexin 4 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SFXN4 mRNA CTD PMID:18313992 NCBI chr 1:282,213,610...282,236,851
Ensembl chr 1:282,213,675...282,235,974
JBrowse link
G Sgpp1 sphingosine-1-phosphate phosphatase 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SGPP1 mRNA CTD PMID:18313992 NCBI chr 6:98,675,324...98,696,492
Ensembl chr 6:98,675,326...98,695,988
JBrowse link
G Slc1a4 solute carrier family 1 member 4 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SLC1A4 mRNA CTD PMID:15784690 NCBI chr14:104,582,884...104,612,417
Ensembl chr14:104,581,190...104,612,597
JBrowse link
G Slc1a5 solute carrier family 1 member 5 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SLC1A5 mRNA CTD PMID:15784690 NCBI chr 1:78,710,686...78,724,789
Ensembl chr 1:78,710,539...78,724,794
JBrowse link
G Slc22a1 solute carrier family 22 member 1 increases uptake ISO SLC22A1 protein results in increased uptake of Lamivudine CTD PMID:19141712 NCBI chr 1:48,273,639...48,300,645
Ensembl chr 1:48,273,611...48,300,655
JBrowse link
G Slc22a2 solute carrier family 22 member 2 increases uptake ISO SLC22A2 protein results in increased uptake of Lamivudine CTD PMID:19141712 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
G Slc22a3 solute carrier family 22 member 3 increases uptake ISO SLC22A3 protein results in increased uptake of Lamivudine CTD PMID:19141712 NCBI chr 1:48,433,079...48,521,261
Ensembl chr 1:48,433,079...48,521,256
JBrowse link
G Slc25a12 solute carrier family 25 member 12 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of SLC25A12 mRNA CTD PMID:18313992 NCBI chr 3:57,881,951...57,998,214
Ensembl chr 3:57,882,370...57,957,346
JBrowse link
G Slc25a15 solute carrier family 25 member 15 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SLC25A15 mRNA CTD PMID:18313992 NCBI chr16:74,505,318...74,554,523
Ensembl chr16:74,531,564...74,554,529
JBrowse link
G Slc25a19 solute carrier family 25 member 19 multiple interactions ISO SLC25A19 protein affects the susceptibility to [Stavudine co-treated with Lamivudine co-treated with Indinavir]; SLC25A19 protein affects the susceptibility to [Zidovudine co-treated with Lamivudine co-treated with Indinavir]
[Zidovudine co-treated with Lamivudine] results in decreased expression of SLC25A19 mRNA
CTD PMID:15951836, PMID:18313992 NCBI chr10:104,166,594...104,179,523
Ensembl chr10:104,166,598...104,179,523
JBrowse link
G Slc25a2 solute carrier family 25 member 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of SLC25A2 mRNA CTD PMID:18313992 NCBI chr18:30,774,205...30,775,401
Ensembl chr18:30,774,205...30,775,401
JBrowse link
G Slc25a20 solute carrier family 25 member 20 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SLC25A20 mRNA CTD PMID:18313992 NCBI chr 8:117,455,308...117,476,762
Ensembl chr 8:117,455,262...117,476,734
JBrowse link
G Slc25a29 solute carrier family 25 member 29 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SLC25A29 mRNA CTD PMID:18313992 NCBI chr 6:132,736,964...132,747,912
Ensembl chr 6:132,735,883...132,747,828
JBrowse link
G Slc25a3 solute carrier family 25 member 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of SLC25A3 mRNA CTD PMID:18313992 NCBI chr 7:31,816,601...31,824,064
Ensembl chr 7:31,816,602...31,824,071
JBrowse link
G Slc25a4 solute carrier family 25 member 4 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SLC25A4 mRNA CTD PMID:18313992 NCBI chr16:49,266,903...49,270,698
Ensembl chr16:49,266,903...49,270,698
JBrowse link
G Slc28a1 solute carrier family 28 member 1 multiple interactions ISO Lamivudine inhibits the reaction [SLC28A1 protein results in increased transport of Uridine] CTD PMID:10772724 NCBI chr 1:142,948,942...142,992,410
Ensembl chr 1:142,950,540...142,992,615
JBrowse link
G Slc31a1 solute carrier family 31 member 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SLC31A1 mRNA CTD PMID:15784690 NCBI chr 5:78,222,504...78,249,358
Ensembl chr 5:78,222,504...78,249,358
JBrowse link
G Slc3a2 solute carrier family 3 member 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SLC3A2 mRNA CTD PMID:15784690 NCBI chr 1:224,906,566...224,921,029
Ensembl chr 1:224,906,554...224,921,092
JBrowse link
G Slc40a1 solute carrier family 40 member 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SLC40A1 mRNA CTD PMID:18313992 NCBI chr 9:52,819,451...52,830,461
Ensembl chr 9:52,894,365...52,912,293
JBrowse link
G Slc6a4 solute carrier family 6 member 4 multiple interactions
increases expression
ISO [Lamivudine co-treated with IFNA2 protein] results in increased expression of SLC6A4 mRNA; Lamivudine promotes the reaction [SLC6A4 protein results in increased uptake of Serotonin]; Lamivudine results in increased expression of and results in increased activity of SLC6A4 protein
Lamivudine results in increased expression of SLC6A4 mRNA
CTD PMID:16476009 NCBI chr10:63,153,656...63,188,377
Ensembl chr10:63,153,651...63,176,463
JBrowse link
G Spink5 serine peptidase inhibitor, Kazal type 5 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of SPINK5 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of SPINK5 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of SPINK5 mRNA CTD PMID:16931933 NCBI chr18:35,118,300...35,190,458
Ensembl chr18:35,121,967...35,191,069
Ensembl chr 1:35,121,967...35,191,069
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of STAR mRNA CTD PMID:18313992 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link
G Stc2 stanniocalcin 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of STC2 mRNA CTD PMID:15784690 NCBI chr10:16,542,909...16,552,675
Ensembl chr10:16,542,882...16,553,295
JBrowse link
G Sub1 SUB1 regulator of transcription multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SUB1 mRNA CTD PMID:16931933 NCBI chr 2:62,019,902...62,034,704
Ensembl chr 2:62,022,567...62,034,628
JBrowse link
G Tcea1 transcription elongation factor A1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of TCEA1 mRNA CTD PMID:15784690 NCBI chr 5:14,511,183...14,548,494
Ensembl chr 5:14,511,183...14,548,429
JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases expression ISO Lamivudine results in decreased expression of TGFB1 protein CTD PMID:15309715 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Timm17b translocase of inner mitochondrial membrane 17b multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of TIMM17B mRNA CTD PMID:18313992 NCBI chr  X:15,441,369...15,448,452
Ensembl chr  X:15,441,651...15,448,403
JBrowse link
G Timm23 translocase of inner mitochondrial membrane 23 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of TIMM23 mRNA CTD PMID:18313992 NCBI chr16:8,324,038...8,350,067
Ensembl chr16:8,324,036...8,350,067
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 decreases expression ISO Lamivudine results in decreased expression of TIMP1 protein CTD PMID:15309715 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of TIMP2 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of TIMP2 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of TIMP2 mRNA CTD PMID:16931933 NCBI chr10:107,338,465...107,386,072
Ensembl chr10:107,338,465...107,386,072
JBrowse link
G Tk2 thymidine kinase 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of TK2 mRNA CTD PMID:18313992 NCBI chr19:917,203...939,236
Ensembl chr19:917,203...939,221
JBrowse link
G Trib3 tribbles pseudokinase 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of TRIB3 mRNA CTD PMID:15784690 NCBI chr 3:147,814,056...147,819,650
Ensembl chr 3:147,813,473...147,819,571
JBrowse link
G Trim42 tripartite motif-containing 42 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of TRIM42 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of TRIM42 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of TRIM42 mRNA CTD PMID:16931933 NCBI chr 8:105,205,041...105,226,541
Ensembl chr 8:105,204,993...105,226,588
JBrowse link
G Twnk twinkle mtDNA helicase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of TWNK mRNA CTD PMID:18313992 NCBI chr 1:264,756,060...264,762,892
Ensembl chr 1:264,756,499...264,762,892
JBrowse link
G Tyms thymidylate synthetase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of TYMS mRNA CTD PMID:15784690 NCBI chr 9:121,918,875...121,931,564
Ensembl chr 9:121,918,947...121,931,564
JBrowse link
G Tyrp1 tyrosinase-related protein 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of TYRP1 mRNA CTD PMID:15784690 NCBI chr 5:98,387,291...98,406,083
Ensembl chr 5:98,387,291...98,406,083
JBrowse link
G Uqcrb ubiquinol-cytochrome c reductase binding protein multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of UQCRB mRNA CTD PMID:18313992 NCBI chr 7:71,264,501...71,269,869
Ensembl chr 7:71,264,514...71,269,869
Ensembl chr 1:71,264,514...71,269,869
JBrowse link
G Uqcrc1 ubiquinol-cytochrome c reductase core protein 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of UQCRC1 mRNA CTD PMID:17526437, PMID:18313992 NCBI chr 8:117,679,328...117,691,073
Ensembl chr 8:117,679,278...117,691,071
JBrowse link
G Uqcrc2 ubiquinol cytochrome c reductase core protein 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of UQCRC2 mRNA CTD PMID:18313992 NCBI chr 1:190,555,177...190,585,741
Ensembl chr 1:190,555,177...190,585,734
JBrowse link
G Vdac1 voltage-dependent anion channel 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of VDAC1 mRNA CTD PMID:18313992 NCBI chr10:37,724,915...37,752,827
Ensembl chr10:37,724,915...37,752,826
JBrowse link
G Vdr vitamin D receptor multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of VDR mRNA CTD PMID:11741158 NCBI chr 7:139,344,452...139,394,138
Ensembl chr 7:139,342,063...139,394,166
JBrowse link
G Vps4b vacuolar protein sorting 4 homolog B multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of VPS4B mRNA CTD PMID:16931933 NCBI chr13:26,825,261...26,850,460
Ensembl chr13:26,825,261...26,850,460
JBrowse link
G Wars1 tryptophanyl-tRNA synthetase 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of WARS1 mRNA CTD PMID:15784690 NCBI chr 6:132,771,026...132,802,262
Ensembl chr 6:132,771,021...132,802,210
JBrowse link
G Wnt10a Wnt family member 10A multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of WNT10A mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of WNT10A mRNA CTD PMID:16931933 NCBI chr 9:82,053,581...82,066,047
Ensembl chr 9:82,053,581...82,066,047
JBrowse link
G Yars1 tyrosyl-tRNA synthetase 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of YARS1 mRNA CTD PMID:15784690 NCBI chr 5:147,375,350...147,403,578
Ensembl chr 5:147,375,350...147,403,571
JBrowse link
nevirapine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression EXP Nevirapine results in increased expression of ABCB1A mRNA CTD PMID:23947594 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Adamts9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 decreases expression EXP Nevirapine metabolite results in decreased expression of ADAMTS9 mRNA; Nevirapine results in decreased expression of ADAMTS9 mRNA CTD PMID:23947594 NCBI chr 4:124,660,254...124,860,997
Ensembl chr 4:124,660,262...124,858,250
JBrowse link
G Adgrf5 adhesion G protein-coupled receptor F5 increases expression EXP Nevirapine metabolite results in increased expression of ADGRF5 mRNA CTD PMID:23947594 NCBI chr 9:20,091,121...20,195,706
Ensembl chr 9:20,091,099...20,195,566
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing increases expression
increases secretion
ISO Nevirapine results in increased expression of ADIPOQ mRNA
Nevirapine results in increased secretion of ADIPOQ protein
CTD PMID:21619898 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Aif1 allograft inflammatory factor 1 decreases expression EXP Nevirapine metabolite results in decreased expression of AIF1 mRNA CTD PMID:23947594 NCBI chr20:5,161,350...5,167,176
Ensembl chr20:5,161,333...5,166,448
JBrowse link
G Alb albumin affects binding ISO Nevirapine binds to ALB protein CTD PMID:15814459, PMID:16336266 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Apoa1 apolipoprotein A1 increases expression ISO Nevirapine results in increased expression of APOA1 protein CTD PMID:19667106 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Ar androgen receptor increases expression ISO Nevirapine results in increased expression of AR mRNA; Nevirapine results in increased expression of AR protein CTD PMID:19152342 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Armcx2 armadillo repeat containing, X-linked 2 decreases expression EXP Nevirapine metabolite results in decreased expression of ARMCX2 mRNA; Nevirapine results in decreased expression of ARMCX2 mRNA CTD PMID:23947594 NCBI chr  X:105,617,383...105,622,209
Ensembl chr  X:105,617,385...105,622,156
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator increases expression EXP Nevirapine metabolite results in increased expression of ARNT mRNA CTD PMID:23947594 NCBI chr 2:196,594,178...196,651,486
Ensembl chr 2:196,594,303...196,651,179
JBrowse link
G Cd36 CD36 molecule increases expression EXP Nevirapine metabolite results in increased expression of CD36 mRNA CTD PMID:23947594 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha increases expression ISO Nevirapine results in increased expression of CEBPA mRNA CTD PMID:21619898 NCBI chr 1:91,363,492...91,366,164
Ensembl chr 1:91,363,492...91,366,164
JBrowse link
G Ces2h carboxylesterase 2H increases expression EXP Nevirapine results in increased expression of CES2 mRNA CTD PMID:23947594 NCBI chr19:37,052,555...37,067,176
Ensembl chr19:37,052,556...37,067,156
JBrowse link
G Ciita class II, major histocompatibility complex, transactivator increases expression ISO Nevirapine results in increased expression of CIITA CTD PMID:26626330 NCBI chr10:5,212,621...5,260,641
Ensembl chr10:5,213,350...5,260,608
JBrowse link
G Clec4a3 C-type lectin domain family 4, member A3 decreases expression EXP Nevirapine results in decreased expression of CLEC4A1 mRNA CTD PMID:23947594 NCBI chr 4:155,913,366...155,923,079
Ensembl chr 4:155,913,366...155,923,079
JBrowse link
G Clec4m C-type lectin domain family 4 member M increases expression EXP Nevirapine metabolite results in increased expression of CD209B mRNA CTD PMID:23947594 NCBI chr12:2,817,633...2,826,303
Ensembl chr12:2,816,065...2,826,378
JBrowse link
G Cotl1 coactosin-like F-actin binding protein 1 decreases expression EXP Nevirapine results in decreased expression of COTL1 mRNA CTD PMID:23947594 NCBI chr19:52,465,074...52,499,433
Ensembl chr19:52,465,087...52,499,433
JBrowse link
G Cux2 cut-like homeobox 2 decreases expression EXP Nevirapine metabolite results in decreased expression of CUX2 mRNA CTD PMID:23947594 NCBI chr12:40,016,774...40,221,067
Ensembl chr12:40,018,937...40,219,291
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression EXP Nevirapine metabolite results in increased expression of CYP2B1 mRNA; Nevirapine results in increased expression of CYP2B1 mRNA CTD PMID:23947594 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions ISO [Nevirapine results in increased activity of NR1I3 protein alternative form] which results in increased expression of CYP2B6 mRNA; [Nevirapine results in increased activity of NR1I3 protein] which results in increased expression of CYP2B6 mRNA CTD PMID:17041008 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 affects binding EXP Nevirapine binds to CYP2C11 protein CTD PMID:22793666 NCBI chr 1:257,676,172...258,004,428
Ensembl chr 1:257,970,345...258,004,434
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 affects binding
increases expression
EXP Nevirapine binds to CYP3A23-3A1 protein
Nevirapine results in increased expression of CYP3A23-3A1 mRNA
CTD PMID:22793666, PMID:23947594 NCBI chr12:11,053,888...11,082,742
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 increases expression EXP Nevirapine results in increased expression of CYP3A9 mRNA CTD PMID:23947594 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
JBrowse link
G Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 increases expression EXP Nevirapine metabolite results in increased expression of CYP4B1 mRNA CTD PMID:23947594 NCBI chr 5:134,508,728...134,526,103
Ensembl chr 5:134,508,730...134,526,089
JBrowse link
G Dapk1 death associated protein kinase 1 increases expression EXP Nevirapine metabolite results in increased expression of DAPK1 mRNA CTD PMID:23947594 NCBI chr17:4,297,038...4,454,941
Ensembl chr17:4,297,224...4,454,778
JBrowse link
G Dbp D-box binding PAR bZIP transcription factor decreases expression EXP Nevirapine metabolite results in decreased expression of DBP mRNA CTD PMID:23947594 NCBI chr 1:101,687,896...101,692,845
Ensembl chr 1:101,687,855...101,692,846
JBrowse link
G Ddhd1 DDHD domain containing 1 decreases expression EXP Nevirapine results in decreased expression of DDHD1 mRNA CTD PMID:23947594 NCBI chr15:19,963,639...20,032,263
Ensembl chr15:19,965,187...20,032,191
JBrowse link
G Dip2a disco-interacting protein 2 homolog A increases expression EXP Nevirapine results in increased expression of DIP2A mRNA CTD PMID:23947594 NCBI chr20:13,044,056...13,127,971
Ensembl chr20:13,044,104...13,127,487
JBrowse link
G Dnajb5 DnaJ heat shock protein family (Hsp40) member B5 increases expression EXP Nevirapine metabolite results in increased expression of DNAJB5 mRNA CTD PMID:23947594 NCBI chr 5:58,393,197...58,402,162
Ensembl chr 5:58,393,233...58,401,870
JBrowse link
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 increases expression EXP Nevirapine results in increased expression of EDEM1 mRNA CTD PMID:23947594 NCBI chr 4:140,886,644...140,918,654
Ensembl chr 4:140,886,545...140,915,779
JBrowse link
G Egf epidermal growth factor decreases expression ISO Nevirapine results in decreased expression of EGF mRNA CTD PMID:19152342 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Egfr epidermal growth factor receptor decreases expression ISO Nevirapine results in decreased expression of EGFR mRNA CTD PMID:19152342 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Epb41l3 erythrocyte membrane protein band 4.1-like 3 decreases expression EXP Nevirapine results in decreased expression of EPB41L3 mRNA CTD PMID:23947594 NCBI chr 9:117,314,935...117,666,408
Ensembl chr 9:117,538,009...117,666,410
JBrowse link
G Esm1 endothelial cell-specific molecule 1 increases expression EXP Nevirapine metabolite results in increased expression of ESM1 mRNA; Nevirapine results in increased expression of ESM1 mRNA CTD PMID:23947594 NCBI chr 2:45,104,392...45,113,130
Ensembl chr 2:45,104,305...45,113,131
JBrowse link
G Fam107a family with sequence similarity 107, member A increases expression EXP Nevirapine results in increased expression of FAM107A mRNA CTD PMID:23947594 NCBI chr15:18,399,145...18,415,959
Ensembl chr15:18,399,515...18,415,965
JBrowse link
G Fibin fin bud initiation factor homolog increases expression EXP Nevirapine results in increased expression of FIBIN mRNA CTD PMID:23947594 NCBI chr 3:101,545,207...101,547,478
Ensembl chr 3:101,545,208...101,547,478
JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 increases expression EXP Nevirapine metabolite results in increased expression of FKBP5 mRNA; Nevirapine results in increased expression of FKBP5 mRNA CTD PMID:23947594 NCBI chr20:7,976,704...8,097,290
Ensembl chr20:7,976,713...8,019,020
JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 decreases expression EXP Nevirapine metabolite results in decreased expression of FMO1 mRNA CTD PMID:23947594 NCBI chr13:80,712,885...80,745,095
Ensembl chr13:80,712,882...80,745,347
JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta increases expression EXP Nevirapine results in increased expression of GADD45B mRNA CTD PMID:23947594 NCBI chr 7:11,646,283...11,648,338
Ensembl chr 7:11,646,269...11,648,322
JBrowse link
G Glul glutamate-ammonia ligase decreases expression EXP Nevirapine metabolite results in decreased expression of GLUL mRNA CTD PMID:23947594 NCBI chr13:71,331,052...71,340,207
Ensembl chr13:71,331,052...71,340,229
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 increases glutathionylation ISO GSTA1 protein results in increased glutathionylation of Nevirapine metabolite CTD PMID:27989146 NCBI chr 9:27,366,404...27,381,004
Ensembl chr 9:27,368,272...27,452,902
JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases glutathionylation ISO GSTM1 protein results in increased glutathionylation of Nevirapine metabolite CTD PMID:27989146 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases glutathionylation ISO GSTP1 protein results in increased glutathionylation of Nevirapine metabolite CTD PMID:27989146 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Gzma granzyme A decreases expression EXP Nevirapine metabolite results in decreased expression of GZMA mRNA CTD PMID:23947594 NCBI chr 2:44,968,846...44,981,436
Ensembl chr 2:44,968,765...44,981,458
JBrowse link
G Gzmf granzyme F decreases expression EXP Nevirapine metabolite results in decreased expression of GZMF mRNA CTD PMID:23947594 NCBI chr15:35,182,405...35,195,725
Ensembl chr15:35,184,364...35,195,725
JBrowse link
G Hao2 hydroxyacid oxidase 2 decreases expression EXP Nevirapine metabolite results in decreased expression of HAO2 mRNA; Nevirapine results in decreased expression of HAO2 mRNA CTD PMID:23947594 NCBI chr 2:200,785,492...200,808,868
Ensembl chr 2:200,778,122...200,808,857
JBrowse link
G Hdc histidine decarboxylase decreases expression EXP Nevirapine metabolite results in decreased expression of HDC mRNA CTD PMID:23947594 NCBI chr 3:119,057,524...119,075,599
Ensembl chr 3:119,057,517...119,075,619
JBrowse link
G Hgf hepatocyte growth factor decreases secretion ISO Nevirapine results in decreased secretion of HGF protein CTD PMID:21619898 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 increases expression EXP Nevirapine metabolite results in increased expression of HMGCS2 mRNA; Nevirapine results in increased expression of HMGCS2 mRNA CTD PMID:23947594 NCBI chr 2:200,452,623...200,480,785
Ensembl chr 2:200,452,624...200,479,423
JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase increases expression EXP Nevirapine metabolite results in increased expression of HPGD mRNA CTD PMID:23947594 NCBI chr16:37,457,134...37,495,758
Ensembl chr16:37,457,135...37,495,758
JBrowse link
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 decreases expression EXP Nevirapine metabolite results in decreased expression of HSD17B2 mRNA CTD PMID:23947594 NCBI chr19:50,246,404...50,317,892
Ensembl chr19:50,246,402...50,317,891
JBrowse link
G Ifng interferon gamma increases expression ISO
EXP
Nevirapine results in increased expression of IFNG protein CTD PMID:23947594 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Igh-6 immunoglobulin heavy chain 6 increases expression EXP Nevirapine results in increased expression of IGH-6 mRNA CTD PMID:23947594 Ensembl chr 6:138,092,131...138,093,643 JBrowse link
G Il22ra2 interleukin 22 receptor subunit alpha 2 increases expression EXP Nevirapine metabolite results in increased expression of IL22RA2 mRNA CTD PMID:23947594 NCBI chr 1:15,084,136...15,107,423
Ensembl chr 1:15,093,599...15,106,954
JBrowse link
G Il6 interleukin 6 decreases secretion ISO Nevirapine results in decreased secretion of IL6 protein CTD PMID:21619898 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Inhbe inhibin subunit beta E decreases expression EXP Nevirapine metabolite results in decreased expression of INHBE mRNA CTD PMID:23947594 NCBI chr 7:70,641,423...70,642,848
Ensembl chr 7:70,640,075...70,643,169
JBrowse link
G Inmt indolethylamine N-methyltransferase increases expression EXP Nevirapine results in increased expression of INMT mRNA CTD PMID:23947594 NCBI chr 4:85,381,907...85,386,203
Ensembl chr 4:85,381,889...85,386,231
JBrowse link
G Insig2 insulin induced gene 2 increases expression EXP Nevirapine results in increased expression of INSIG2 mRNA CTD PMID:23947594 NCBI chr13:37,264,818...37,292,718
Ensembl chr13:37,266,312...37,287,458
JBrowse link
G Irgm immunity-related GTPase M decreases expression EXP Nevirapine results in decreased expression of IRGM mRNA CTD PMID:23947594 NCBI chr10:34,213,885...34,221,968
Ensembl chr10:34,213,936...34,221,928
JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 increases expression EXP Nevirapine results in increased expression of ITPR1 mRNA CTD PMID:23947594 NCBI chr 4:140,247,297...140,580,749
Ensembl chr 4:140,247,313...140,580,748
JBrowse link
G Klf15 Kruppel-like factor 15 increases expression EXP Nevirapine metabolite results in increased expression of KLF15 mRNA CTD PMID:23947594 NCBI chr 4:122,364,688...122,377,690
Ensembl chr 4:122,365,093...122,377,659
JBrowse link
G Krt18 keratin 18 increases expression ISO Nevirapine results in increased expression of KRT18 protein CTD PMID:19152342 NCBI chr 7:143,629,455...143,633,131
Ensembl chr 7:143,629,455...143,633,131
JBrowse link
G Krt23 keratin 23 increases expression EXP Nevirapine metabolite results in increased expression of KRT23 mRNA CTD PMID:23947594 NCBI chr10:87,391,623...87,407,634
Ensembl chr10:87,391,623...87,407,634
JBrowse link
G Lcat lecithin cholesterol acyltransferase increases expression ISO Nevirapine results in increased expression of LCAT protein CTD PMID:19667106 NCBI chr19:37,913,333...37,916,799
Ensembl chr19:37,913,336...37,916,813
JBrowse link
G Lep leptin increases expression ISO Nevirapine results in increased expression of LEP mRNA CTD PMID:21619898 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Lifr LIF receptor subunit alpha increases expression EXP Nevirapine metabolite results in increased expression of LIFR mRNA CTD PMID:23947594 NCBI chr 2:56,424,910...56,489,346
Ensembl chr 2:56,426,367...56,489,415
JBrowse link
G Lilrb3l leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3-like decreases expression EXP Nevirapine results in decreased expression of LILRB3L mRNA CTD PMID:23947594 NCBI chr 1:63,759,638...63,849,278
Ensembl chr 1:63,759,638...64,013,289
JBrowse link
G Lipg lipase G, endothelial type decreases expression EXP Nevirapine metabolite results in decreased expression of LIPG mRNA; Nevirapine results in decreased expression of LIPG mRNA CTD PMID:23947594 NCBI chr18:70,903,528...70,924,434
Ensembl chr18:70,901,710...70,924,708
JBrowse link
G Lpin1 lipin 1 increases expression EXP Nevirapine metabolite results in increased expression of LPIN1 mRNA CTD PMID:23947594 NCBI chr 6:41,796,214...41,905,149
Ensembl chr 6:41,799,749...41,870,046
JBrowse link
G Lpl lipoprotein lipase increases expression ISO Nevirapine results in increased expression of LPL mRNA CTD PMID:21619898 NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496
JBrowse link
G Lrg1 leucine-rich alpha-2-glycoprotein 1 increases expression EXP Nevirapine metabolite results in increased expression of LRG1 mRNA CTD PMID:23947594 NCBI chr 9:10,952,424...10,954,664
Ensembl chr 9:10,952,374...10,954,681
JBrowse link
G Ly86 lymphocyte antigen 86 decreases expression EXP Nevirapine results in decreased expression of LY86 mRNA CTD PMID:23947594 NCBI chr17:28,104,535...28,191,447
Ensembl chr17:28,104,589...28,191,436
JBrowse link
G Meox2 mesenchyme homeobox 2 increases expression EXP Nevirapine results in increased expression of MEOX2 mRNA CTD PMID:23947594 NCBI chr 6:56,625,768...56,689,195
Ensembl chr 6:56,625,650...56,689,238
JBrowse link
G Mgp matrix Gla protein increases expression EXP Nevirapine results in increased expression of MGP mRNA CTD PMID:23947594 NCBI chr 4:170,856,783...170,860,105
Ensembl chr 4:170,856,751...170,860,225
JBrowse link
G Mrc1 mannose receptor, C type 1 increases expression EXP Nevirapine metabolite results in increased expression of MRC1 mRNA CTD PMID:23947594 NCBI chr17:81,352,700...81,433,743
Ensembl chr17:81,352,700...81,433,743
JBrowse link
G Ms4a7 membrane spanning 4-domains A7 decreases expression EXP Nevirapine results in decreased expression of MS4A7 mRNA CTD PMID:23947594 NCBI chr 1:227,490,777...227,506,819
Ensembl chr 1:227,490,777...227,506,822
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase increases expression EXP Nevirapine metabolite results in increased expression of NAMPT mRNA CTD PMID:23947594 NCBI chr 6:52,122,085...52,156,473
Ensembl chr 6:52,122,085...52,156,472
JBrowse link
G Ndufaf4 NADH:ubiquinone oxidoreductase complex assembly factor 4 increases expression EXP Nevirapine results in increased expression of NDUFAF4 mRNA CTD PMID:23947594 NCBI chr 5:39,251,370...39,256,542
Ensembl chr 5:39,251,337...39,257,512
JBrowse link
G Nlrc5 NLR family, CARD domain containing 5 increases expression ISO Nevirapine results in increased expression of NLRC5 CTD PMID:26626330 NCBI chr19:10,904,381...11,006,202
Ensembl chr19:10,905,542...10,976,396
JBrowse link
G Npas2 neuronal PAS domain protein 2 decreases expression EXP Nevirapine metabolite results in decreased expression of NPAS2 mRNA; Nevirapine results in decreased expression of NPAS2 mRNA CTD PMID:23947594 NCBI chr 9:45,901,262...46,081,880
Ensembl chr 9:45,901,741...46,081,880
JBrowse link
G Nptx2 neuronal pentraxin 2 increases expression EXP Nevirapine results in increased expression of NPTX2 mRNA CTD PMID:23947594 NCBI chr12:12,014,638...12,025,547
Ensembl chr12:12,013,911...12,025,549
JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 decreases expression EXP Nevirapine metabolite results in decreased expression of NR1D1 mRNA CTD PMID:23947594 NCBI chr10:86,683,875...86,690,815
Ensembl chr10:86,683,875...86,690,815
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions ISO [Nevirapine results in increased activity of NR1I3 protein alternative form] which results in increased expression of CYP2B6 mRNA; [Nevirapine results in increased activity of NR1I3 protein] which results in increased expression of CYP2B6 mRNA CTD PMID:17041008 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Nrep neuronal regeneration related protein decreases expression EXP Nevirapine metabolite results in decreased expression of NREP mRNA; Nevirapine results in decreased expression of NREP mRNA CTD PMID:23947594 NCBI chr18:26,183,753...26,212,796
Ensembl chr18:26,185,259...26,211,445
JBrowse link
G P2rx7 purinergic receptor P2X 7 decreases expression EXP Nevirapine results in decreased expression of P2RX7 mRNA CTD PMID:23947594 NCBI chr12:39,353,613...39,396,042
Ensembl chr12:39,353,613...39,396,042
JBrowse link
G Pcp4l1 Purkinje cell protein 4-like 1 decreases expression EXP Nevirapine results in decreased expression of PCP4L1 mRNA CTD PMID:23947594 NCBI chr13:89,542,377...89,565,920
Ensembl chr13:89,542,378...89,565,813
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 increases expression EXP Nevirapine metabolite results in increased expression of PDK4 mRNA CTD PMID:23947594 NCBI chr 4:30,546,772...30,556,774
Ensembl chr 4:30,546,664...30,556,814
JBrowse link
G Pik3ip1 phosphoinositide-3-kinase interacting protein 1 increases expression EXP Nevirapine results in increased expression of PIK3IP1 mRNA CTD PMID:23947594 NCBI chr14:83,559,397...83,572,481
Ensembl chr14:83,560,541...83,572,473
JBrowse link
G Pir pirin increases expression EXP Nevirapine metabolite results in increased expression of PIR mRNA CTD PMID:23947594 NCBI chr  X:31,852,322...31,968,152
Ensembl chr  X:31,852,323...31,968,152
JBrowse link
G Pnpla2 patatin-like phospholipase domain containing 2 increases expression EXP Nevirapine metabolite results in increased expression of PNPLA2 mRNA CTD PMID:23947594 NCBI chr 1:214,434,638...214,439,720
Ensembl chr 1:214,434,626...214,439,720
JBrowse link
G Por cytochrome p450 oxidoreductase increases expression EXP Nevirapine metabolite results in increased expression of POR mRNA; Nevirapine results in increased expression of POR mRNA CTD PMID:23947594 NCBI chr12:23,998,411...24,017,063
Ensembl chr12:23,998,411...24,046,814
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression ISO Nevirapine results in increased expression of PPARG mRNA CTD PMID:21619898 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ppp2r2b protein phosphatase 2, regulatory subunit B, beta decreases expression EXP Nevirapine metabolite results in decreased expression of PPP2R2B mRNA; Nevirapine results in decreased expression of PPP2R2B mRNA CTD PMID:23947594 NCBI chr18:36,985,709...37,421,383
Ensembl chr18:36,985,714...37,245,809
JBrowse link
G Prf1 perforin 1 decreases expression EXP Nevirapine metabolite results in decreased expression of PRF1 mRNA CTD PMID:23947594 NCBI chr20:30,915,294...30,920,804
Ensembl chr20:30,915,213...30,921,382
JBrowse link
G Pycr1 pyrroline-5-carboxylate reductase 1 decreases expression EXP Nevirapine metabolite results in decreased expression of PYCR1 mRNA CTD PMID:23947594 NCBI chr10:109,817,300...109,822,218
Ensembl chr10:109,818,177...109,821,807
JBrowse link
G Rbm3 RNA binding motif protein 3 increases expression EXP Nevirapine results in increased expression of RBM3 mRNA CTD PMID:23947594 NCBI chr  X:15,098,880...15,102,344
Ensembl chr  X:15,098,904...15,102,340
JBrowse link
G Retreg1 reticulophagy regulator 1 increases expression EXP Nevirapine metabolite results in increased expression of RETREG1 mRNA; Nevirapine results in increased expression of RETREG1 mRNA CTD PMID:23947594 NCBI chr 2:78,391,921...78,401,569
Ensembl chr 2:78,391,921...78,399,987
JBrowse link
G Rhbdd2 rhomboid domain containing 2 increases expression EXP Nevirapine results in increased expression of RHBDD2 mRNA CTD PMID:23947594 NCBI chr12:24,091,132...24,102,081
Ensembl chr12:24,092,004...24,102,084
JBrowse link
G Rprm reprimo, TP53 dependent G2 arrest mediator homolog decreases expression EXP Nevirapine metabolite results in decreased expression of RPRM mRNA CTD PMID:23947594 NCBI chr 3:39,595,301...39,596,718
Ensembl chr 3:39,595,301...39,596,718
JBrowse link
G S100a7a S100 calcium binding protein A7A increases expression EXP Nevirapine metabolite results in increased expression of S100A7A mRNA CTD PMID:23947594 NCBI chr 2:190,058,093...190,063,132
Ensembl chr 2:190,058,093...190,062,534
JBrowse link
G Scp2 sterol carrier protein 2 increases expression ISO Nevirapine results in increased expression of SCP2 CTD PMID:26626330 NCBI chr 5:127,647,934...127,735,703
Ensembl chr 5:127,620,274...127,735,739
JBrowse link
G Slamf9 SLAM family member 9 decreases expression EXP Nevirapine results in decreased expression of SLAMF9 mRNA CTD PMID:23947594 NCBI chr13:90,836,419...90,856,913
Ensembl chr13:90,836,361...90,839,411
JBrowse link
G Slc34a2 solute carrier family 34 member 2 decreases expression EXP Nevirapine metabolite results in decreased expression of SLC34A2 mRNA CTD PMID:23947594 NCBI chr14:60,257,211...60,276,516
Ensembl chr14:60,256,712...60,276,794
JBrowse link
G Slc5a5 solute carrier family 5 member 5 multiple interactions ISO [Nevirapine co-treated with TSHB protein] results in increased expression of SLC5A5 mRNA; [Nevirapine co-treated with TSHB protein] results in increased expression of SLC5A5 protein CTD PMID:16030158 NCBI chr16:20,297,414...20,307,401
Ensembl chr16:20,297,414...20,307,400
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 increases expression
decreases expression
ISO
EXP
Nevirapine results in increased expression of SREBF1 mRNA
Nevirapine metabolite results in decreased expression of SREBF1 mRNA
CTD PMID:21619898, PMID:23947594 NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 increases activity EXP Nevirapine metabolite results in increased activity of SULT1A1 protein; Nevirapine results in increased activity of SULT1A1 protein CTD PMID:27417440 NCBI chr 1:198,100,586...198,104,106
Ensembl chr 1:198,100,586...198,104,109
JBrowse link
G Tg thyroglobulin increases expression ISO Nevirapine results in increased expression of TG mRNA; Nevirapine results in increased expression of TG protein CTD PMID:16030158 NCBI chr 7:107,467,260...107,652,897
Ensembl chr 7:107,467,260...107,652,899
JBrowse link
G Tmem159 transmembrane protein 159 decreases expression EXP Nevirapine results in decreased expression of TMEM159 mRNA CTD PMID:23947594 NCBI chr 1:189,870,596...189,889,485
Ensembl chr 1:189,870,622...189,889,484
JBrowse link
G Tmem64 transmembrane protein 64 increases expression EXP Nevirapine metabolite results in increased expression of TMEM64 mRNA; Nevirapine results in increased expression of TMEM64 mRNA CTD PMID:23947594 NCBI chr 5:28,850,864...28,898,203
Ensembl chr 5:28,850,950...28,867,227
JBrowse link
G Tox3 TOX high mobility group box family member 3 increases expression EXP Nevirapine results in increased expression of TOX3 mRNA CTD PMID:23947594 NCBI chr19:18,079,022...18,188,366
Ensembl chr19:18,079,094...18,188,330
JBrowse link
G Tpo thyroid peroxidase increases expression ISO Nevirapine results in increased expression of TPO mRNA; Nevirapine results in increased expression of TPO protein CTD PMID:16030158 NCBI chr 6:49,020,918...49,089,855
Ensembl chr 6:49,021,044...49,089,855
JBrowse link
G Trim24 tripartite motif-containing 24 decreases expression EXP Nevirapine results in decreased expression of TRIM24 mRNA CTD PMID:23947594 NCBI chr 4:65,632,278...65,684,746
Ensembl chr 4:65,637,407...65,684,743
JBrowse link
G Trim63 tripartite motif containing 63 increases expression EXP Nevirapine metabolite results in increased expression of TRIM63 mRNA CTD PMID:23947594 NCBI chr 5:152,533,362...152,547,138
Ensembl chr 5:152,533,349...152,547,179
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 increases expression EXP Nevirapine results in increased expression of TSC22D3 mRNA CTD PMID:23947594 NCBI chr  X:111,884,285...111,944,693
Ensembl chr  X:111,884,295...111,887,906
JBrowse link
G Tshb thyroid stimulating hormone subunit beta multiple interactions ISO [Nevirapine co-treated with TSHB protein] results in increased expression of SLC5A5 mRNA; [Nevirapine co-treated with TSHB protein] results in increased expression of SLC5A5 protein; Nevirapine promotes the reaction [TSHB protein affects the abundance of Iodine]; sodium perchlorate inhibits the reaction [Nevirapine promotes the reaction [TSHB protein affects the abundance of Iodine]] CTD PMID:16030158 NCBI chr 2:205,207,799...205,215,199
Ensembl chr 2:205,207,799...205,212,681
JBrowse link
G Tshr thyroid stimulating hormone receptor increases expression ISO Nevirapine results in increased expression of TSHR mRNA CTD PMID:16030158 NCBI chr 6:115,170,290...115,306,871
Ensembl chr 6:115,170,865...115,306,871
JBrowse link
G Tsku tsukushi, small leucine rich proteoglycan increases expression EXP Nevirapine results in increased expression of TSKU mRNA CTD PMID:23947594 NCBI chr 1:163,317,281...163,328,697
Ensembl chr 1:163,317,282...163,328,591
JBrowse link
G Ucp1 uncoupling protein 1 increases expression ISO Nevirapine results in increased expression of UCP1 CTD PMID:16038477 NCBI chr19:24,456,976...24,464,808
Ensembl chr19:24,456,976...24,464,807
JBrowse link
G Ucp3 uncoupling protein 3 increases expression EXP Nevirapine metabolite results in increased expression of UCP3 mRNA CTD PMID:23947594 NCBI chr 1:165,482,912...165,495,895
Ensembl chr 1:165,482,155...165,496,206
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 increases expression EXP Nevirapine metabolite results in increased expression of VCAM1 mRNA CTD PMID:23947594 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression ISO Nevirapine results in decreased expression of VEGFA mRNA CTD PMID:19152342 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Vsnl1 visinin-like 1 decreases expression EXP Nevirapine metabolite results in decreased expression of VSNL1 mRNA; Nevirapine results in decreased expression of VSNL1 mRNA CTD PMID:23947594 NCBI chr 6:37,001,360...37,121,969
Ensembl chr 6:37,001,356...37,122,023
JBrowse link
G Zap70 zeta chain of T cell receptor associated protein kinase 70 increases expression EXP Nevirapine results in increased expression of ZAP70 mRNA CTD PMID:23947594 NCBI chr 9:43,331,149...43,353,097
Ensembl chr 9:43,331,155...43,353,113
JBrowse link
phosphonoformic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO Foscarnet inhibits the reaction [Phosphates results in decreased expression of AKT1 mRNA] CTD PMID:23308213 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Dmp1 dentin matrix acidic phosphoprotein 1 multiple interactions ISO Foscarnet inhibits the reaction [Phosphates results in increased expression of DMP1 mRNA] CTD PMID:20185895 NCBI chr14:6,889,851...6,923,961
Ensembl chr14:6,889,856...6,900,733
JBrowse link
G Phex phosphate regulating endopeptidase homolog, X-linked multiple interactions ISO Foscarnet inhibits the reaction [beta-glycerophosphoric acid results in increased expression of PHEX mRNA] CTD PMID:18500657 NCBI chr  X:40,460,047...40,717,982
Ensembl chr  X:40,460,047...40,717,982
JBrowse link
G Slc16a1 solute carrier family 16 member 1 multiple interactions
increases import
EXP Foscarnet inhibits the reaction [SLC16A1 protein results in increased transport of Benzoic Acid]
SLC16A1 protein results in increased import of Foscarnet
CTD PMID:10579682, PMID:10714609 NCBI chr 2:207,108,552...207,129,352
Ensembl chr 2:207,108,552...207,128,554
JBrowse link
G Slc20a1 solute carrier family 20 member 1 decreases activity
multiple interactions
increases expression
ISO
EXP
Foscarnet results in decreased activity of SLC20A1 protein
Foscarnet inhibits the reaction [Phosphates results in increased expression of SLC20A1 mRNA]
Foscarnet results in increased expression of SLC20A1 mRNA
CTD PMID:15641067, PMID:17438129, PMID:23308213 NCBI chr 3:121,725,204...121,739,160
Ensembl chr 3:121,725,859...121,739,173
JBrowse link
G Slc20a2 solute carrier family 20 member 2 multiple interactions ISO Foscarnet inhibits the reaction [Phosphates results in increased expression of SLC20A2 mRNA] CTD PMID:23308213 NCBI chr16:74,318,287...74,408,030
Ensembl chr16:74,317,899...74,408,030
JBrowse link
G Slc23a2 solute carrier family 23 member 2 multiple interactions ISO Foscarnet inhibits the reaction [Calcium results in increased expression of SLC23A2 mRNA]; Foscarnet inhibits the reaction [Phosphates results in increased expression of SLC23A2 mRNA] CTD PMID:12788230 NCBI chr 3:124,632,491...124,842,225
Ensembl chr 3:124,632,492...124,724,252
JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions ISO Foscarnet inhibits the reaction [Calcium results in increased expression of SPP1 mRNA]; Foscarnet inhibits the reaction [Phosphates results in increased expression of SPP1 mRNA]; Foscarnet inhibits the reaction [Phosphates results in increased expression of SPP1 protein] CTD PMID:12788230, PMID:17383965, PMID:18412142 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Stc1 stanniocalcin 1 increases expression EXP Foscarnet results in increased expression of STC1 mRNA CTD PMID:17438129 NCBI chr15:50,891,137...50,901,791
Ensembl chr15:50,891,127...50,903,162
JBrowse link
tenofovir disoproxil fumarate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb4 ATP binding cassette subfamily B member 4 decreases activity ISO Tenofovir results in decreased activity of ABCB4 protein CTD PMID:28437613 NCBI chr 4:22,133,984...22,192,687
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Acacb acetyl-CoA carboxylase beta affects expression ISO Tenofovir affects the expression of ACACB mRNA CTD PMID:20032539 NCBI chr12:48,127,149...48,238,969
Ensembl chr12:48,127,149...48,238,887
JBrowse link
G Bnip3l BCL2 interacting protein 3 like increases expression ISO Tenofovir results in increased expression of BNIP3L protein CTD PMID:23640862 NCBI chr15:43,643,897...43,667,123
Ensembl chr15:43,643,897...43,667,029
JBrowse link
G Ccl20 C-C motif chemokine ligand 20 increases expression
multiple interactions
ISO Tenofovir results in increased expression of CCL20 mRNA
Tenofovir results in increased expression of and results in increased secretion of CCL20 protein
CTD PMID:24205323 NCBI chr 9:88,918,359...88,921,017
Ensembl chr 9:88,918,433...88,921,001
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression
ISO [Emtricitabine co-treated with Tenofovir] results in increased expression of CDKN1A protein
Tenofovir results in increased expression of CDKN1A protein
CTD PMID:31545371 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases activity ISO Tenofovir results in decreased activity of CYP2E1 protein CTD PMID:17162464 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Edn1 endothelin 1 increases secretion
multiple interactions
ISO Tenofovir results in increased secretion of EDN1 protein
coenzyme Q10 inhibits the reaction [Tenofovir results in increased secretion of EDN1 protein]
CTD PMID:23640862 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha affects phosphorylation ISO Tenofovir affects the phosphorylation of EIF2S1 protein CTD PMID:27041070 NCBI chr 6:102,048,372...102,073,041
Ensembl chr 6:102,048,372...102,073,041
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 increases secretion
multiple interactions
ISO Tenofovir results in increased secretion of HAVCR1 protein
Tenofovir inhibits the reaction [cidofovir results in increased secretion of HAVCR1 protein]
CTD PMID:29738843 NCBI chr10:31,813,819...31,860,934
Ensembl chr10:31,813,814...31,848,379
JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 affects expression ISO Tenofovir affects the expression of HSD11B1 mRNA CTD PMID:20032539 NCBI chr13:111,946,626...111,996,536
Ensembl chr13:111,926,442...111,972,603
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 affects expression ISO Tenofovir affects the expression of HSPD1 protein CTD PMID:27041070 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
JBrowse link
G Lipe lipase E, hormone sensitive type affects expression ISO Tenofovir affects the expression of LIPE mRNA CTD PMID:20032539 NCBI chr 1:82,248,031...82,266,727
Ensembl chr 1:82,248,046...82,266,727
JBrowse link
G Lonp1 lon peptidase 1, mitochondrial affects expression ISO Tenofovir affects the expression of LONP1 protein CTD PMID:27041070 NCBI chr 9:10,428,853...10,441,180
Ensembl chr 9:10,428,853...10,441,177
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 affects phosphorylation ISO Tenofovir affects the phosphorylation of MAPK8 protein CTD PMID:27041070 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II multiple interactions ISO Tenofovir promotes the reaction [Didanosine results in decreased expression of COX2 mRNA] CTD PMID:16940060 NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689
JBrowse link
G Nfkbia NFKB inhibitor alpha decreases expression EXP Tenofovir results in decreased expression of NFKBIA protein CTD PMID:27899301 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nos2 nitric oxide synthase 2 increases expression EXP Tenofovir results in increased expression of NOS2 mRNA; Tenofovir results in increased expression of NOS2 protein CTD PMID:27899301 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions
decreases phosphorylation
ISO coenzyme Q10 inhibits the reaction [Tenofovir results in decreased phosphorylation of NOS3 protein] CTD PMID:23640862 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 affects expression ISO Tenofovir affects the expression of NR3C1 mRNA CTD PMID:20032539 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Nt5e 5' nucleotidase, ecto increases expression ISO Tenofovir results in increased expression of NT5E mRNA CTD PMID:24205323 NCBI chr 8:95,969,002...96,012,733
Ensembl chr 8:95,968,652...96,012,696
JBrowse link
G Nt5m 5',3'-nucleotidase, mitochondrial decreases expression ISO Tenofovir results in decreased expression of NT5M mRNA CTD PMID:24205323 NCBI chr10:46,216,494...46,244,478
Ensembl chr10:46,216,884...46,243,077
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects expression ISO Tenofovir affects the expression of PPARG mRNA CTD PMID:20032539 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase multiple interactions ISO [Emtricitabine co-treated with Tenofovir] results in decreased expression of PRKN protein CTD PMID:31545371 NCBI chr 1:48,880,015...50,069,998 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression EXP Tenofovir results in increased expression of PTGS2 mRNA; Tenofovir results in increased expression of PTGS2 protein CTD PMID:27899301 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
affects localization
increases expression
EXP Melatonin inhibits the reaction [Tenofovir affects the localization of RELA protein]; Melatonin inhibits the reaction [Tenofovir results in increased expression of and results in increased activity of RELA protein]; Melatonin inhibits the reaction [Tenofovir results in increased expression of RELA mRNA]; Tenofovir results in increased expression of and results in increased activity of RELA protein CTD PMID:27899301 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Sirt3 sirtuin 3 increases expression ISO Tenofovir results in increased expression of SIRT3 protein CTD PMID:27041070 NCBI chr 1:213,613,502...213,636,061
Ensembl chr 1:213,613,513...213,635,546
JBrowse link
G Slc22a6 solute carrier family 22 member 6 increases response to substance
increases import
multiple interactions
ISO SLC22A6 protein results in increased susceptibility to Tenofovir
SLC22A6 protein results in increased import of Tenofovir
Probenecid inhibits the reaction [SLC22A6 protein results in increased susceptibility to Tenofovir]; SLC22A6 protein results in increased uptake of and results in increased susceptibility to Tenofovir; Tenofovir inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid]
CTD PMID:23856525, PMID:25448811, PMID:29738843 NCBI chr 1:224,824,809...224,833,284
Ensembl chr 1:224,824,799...224,833,259
JBrowse link
G Slc22a8 solute carrier family 22 member 8 increases response to substance
increases import
ISO SLC22A8 protein results in increased susceptibility to Tenofovir
SLC22A8 protein results in increased import of Tenofovir
CTD PMID:25448811, PMID:29738843 NCBI chr 1:224,799,444...224,818,482
Ensembl chr 1:224,800,252...224,818,482
JBrowse link
G Tnf tumor necrosis factor decreases expression
increases expression
ISO
EXP
Tenofovir results in decreased expression of TNF mRNA
Tenofovir results in increased expression of TNF mRNA; Tenofovir results in increased expression of TNF protein
CTD PMID:24205323, PMID:27899301 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases expression
ISO [Emtricitabine co-treated with Tenofovir] results in increased expression of TP53 protein
Tenofovir results in increased expression of TP53 protein
CTD PMID:31545371 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
zalcitabine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 affects phosphorylation EXP Zalcitabine affects the phosphorylation of AKT1 protein CTD PMID:19781600 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Alb albumin affects binding ISO Zalcitabine binds to ALB protein CTD PMID:15814459 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Ano3 anoctamin 3 multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of ANO3 mRNA CTD PMID:18606552 NCBI chr 3:101,843,516...102,203,368
Ensembl chr 3:101,840,630...102,151,489
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 increases response to substance ISO APEX1 protein mutant form results in increased susceptibility to Zalcitabine CTD PMID:17259346 NCBI chr15:27,849,943...27,852,083
Ensembl chr15:27,849,979...27,852,082
JBrowse link
G Arnt2 aryl hydrocarbon receptor nuclear translocator 2 multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in increased expression of ARNT2 mRNA CTD PMID:18606552 NCBI chr 1:146,399,217...146,556,437
Ensembl chr 1:146,399,217...146,556,171
JBrowse link
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in increased expression of ATP2B4 mRNA CTD PMID:18606552 NCBI chr13:50,091,644...50,153,808
Ensembl chr13:50,091,430...50,153,823
JBrowse link
G Bptf bromodomain PHD finger transcription factor multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in increased expression of BPTF mRNA CTD PMID:18606552 NCBI chr10:95,248,573...95,350,162
Ensembl chr10:95,250,294...95,349,789
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression EXP Zalcitabine results in increased expression of CCL2 protein CTD PMID:17761732 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 increases expression EXP Zalcitabine results in increased expression of CXCL12 mRNA CTD PMID:17292584 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression EXP Zalcitabine results in increased expression of CXCR4 mRNA CTD PMID:17292584 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878
JBrowse link
G Dck deoxycytidine kinase affects response to substance ISO DCK protein affects the susceptibility to Zalcitabine CTD PMID:11952160 NCBI chr14:20,935,442...20,952,939
Ensembl chr14:20,935,369...20,953,095
JBrowse link
G Depdc1b DEP domain containing 1B multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of DEPDC1B mRNA CTD PMID:18606552 NCBI chr 2:39,980,796...40,069,982
Ensembl chr 2:40,000,313...40,069,975
JBrowse link
G Dlg5 discs large MAGUK scaffold protein 5 multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in increased expression of DLG5 mRNA CTD PMID:18606552 NCBI chr15:120,213...230,312
Ensembl chr15:120,372...228,977
JBrowse link
G Esrrg estrogen-related receptor gamma multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of ESRRG mRNA CTD PMID:18606552 NCBI chr13:106,063,799...106,683,353
Ensembl chr13:106,463,368...106,683,436
JBrowse link
G Fam81a family with sequence similarity 81, member A multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of FAM81A mRNA CTD PMID:18606552 NCBI chr 8:76,521,662...76,579,387
Ensembl chr 8:76,521,657...76,579,387
JBrowse link
G Fpgt fucose-1-phosphate guanylyltransferase multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of FPGT mRNA CTD PMID:18606552 NCBI chr 2:261,382,015...261,402,950
Ensembl chr 2:261,382,060...261,402,903
JBrowse link
G Gla galactosidase, alpha multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of GLA mRNA CTD PMID:18606552 NCBI chr  X:105,405,915...105,417,331
Ensembl chr  X:105,406,792...105,417,323
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A increases response to substance
increases expression
multiple interactions
ISO
EXP
HTR2A gene results in increased susceptibility to Zalcitabine
Zalcitabine results in increased expression of HTR2A protein
[alpha-phenyl-1-(2-phenylethyl)-4-piperidinemethanol binds to and results in decreased activity of HTR2A protein] which results in decreased susceptibility to Zalcitabine
CTD PMID:17888573 NCBI chr15:56,666,152...56,732,469
Ensembl chr15:56,666,012...56,735,382
JBrowse link
G Il2ra interleukin 2 receptor subunit alpha decreases expression
multiple interactions
ISO Zalcitabine results in decreased expression of IL2RA mRNA; Zalcitabine results in decreased expression of IL2RA protein
Zidovudine promotes the reaction [Zalcitabine results in decreased expression of IL2RA mRNA]; Zidovudine promotes the reaction [Zalcitabine results in decreased expression of IL2RA protein]
CTD PMID:7606800 NCBI chr17:70,500,672...70,547,929
Ensembl chr17:70,499,083...70,548,071
JBrowse link
G Irf7 interferon regulatory factor 7 multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in increased expression of IRF7 mRNA CTD PMID:18606552 NCBI chr 1:214,249,388...214,252,909
Ensembl chr 1:214,248,837...214,252,456
JBrowse link
G Kif5a kinesin family member 5A multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of KIF5A mRNA CTD PMID:18606552 NCBI chr 7:70,515,832...70,552,897
Ensembl chr 7:70,513,343...70,556,827
JBrowse link
G Lama5 laminin subunit alpha 5 multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in increased expression of LAMA5 mRNA CTD PMID:18606552 NCBI chr 3:175,553,042...175,601,112
Ensembl chr 3:175,553,045...175,601,127
JBrowse link
G Luzp2 leucine zipper protein 2 multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of LUZP2 mRNA CTD PMID:18606552 NCBI chr 1:111,849,494...112,067,502
NCBI chr 1:113,419,707...113,531,330
Ensembl chr 1:111,849,998...113,527,735
JBrowse link
G Midn midnolin multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in increased expression of MIDN mRNA CTD PMID:18606552 NCBI chr 7:12,414,303...12,426,712
Ensembl chr 7:12,414,733...12,424,367
JBrowse link
G Mt-co1 mitochondrially encoded cytochrome c oxidase I decreases expression
multiple interactions
ISO Zalcitabine results in decreased expression of COX1 protein
Uridine inhibits the reaction [Zalcitabine results in decreased expression of COX1 protein]
CTD PMID:17187420, PMID:18823003, PMID:20032772 NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867
JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II decreases expression EXP Zalcitabine results in decreased expression of COX2 mRNA CTD PMID:19781600 NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689
JBrowse link
G Mt-co3 mitochondrially encoded cytochrome c oxidase III decreases expression ISO Zalcitabine results in decreased expression of COX3 protein CTD PMID:17508937 NCBI chr MT:8,599...9,382
Ensembl chr MT:8,599...9,382
JBrowse link
G Ndufb11 NADH:ubiquinone oxidoreductase subunit B11 multiple interactions ISO Zalcitabine inhibits the reaction [Cyclic AMP results in increased phosphorylation of NDUFB11 protein] CTD PMID:17904600 NCBI chr  X:1,787,266...1,789,524
Ensembl chr  X:1,787,266...1,789,524
JBrowse link
G Necab1 N-terminal EF-hand calcium binding protein 1 multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of NECAB1 mRNA CTD PMID:18606552 NCBI chr 5:28,507,596...28,737,556
Ensembl chr 5:28,504,558...28,737,719
JBrowse link
G Nkiras1 NFKB inhibitor interacting Ras-like 1 multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of NKIRAS1 mRNA CTD PMID:18606552 NCBI chr15:8,179,090...8,188,656
Ensembl chr15:8,179,102...8,183,682
JBrowse link
G Notch1 notch receptor 1 increases mutagenesis ISO Zalcitabine results in increased mutagenesis of NOTCH1 gene CTD PMID:18798262 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Npy neuropeptide Y multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in increased expression of NPY mRNA CTD PMID:18606552 NCBI chr 4:79,557,856...79,565,059
Ensembl chr 4:79,557,854...79,565,097
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in increased expression of NTRK2 mRNA alternative form CTD PMID:18606552 NCBI chr17:5,934,651...6,245,778
Ensembl chr17:5,933,729...6,244,676
JBrowse link
G Per2 period circadian regulator 2 multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in increased expression of PER2 mRNA CTD PMID:18606552 NCBI chr 9:98,555,154...98,597,362
Ensembl chr 9:98,555,169...98,597,359
JBrowse link
G Rab27b RAB27B, member RAS oncogene family multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of RAB27B mRNA CTD PMID:18606552 NCBI chr18:68,486,006...68,644,595
Ensembl chr18:68,488,942...68,551,558
JBrowse link
G Reg3b regenerating family member 3 beta multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in increased expression of REG3B mRNA; [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in increased expression of REG3B protein CTD PMID:18606552 NCBI chr 4:109,467,272...109,470,510
Ensembl chr 4:109,467,272...109,470,510
JBrowse link
G RGD1305110 similar to KIAA1841 protein multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of RGD1305110 mRNA CTD PMID:18606552 NCBI chr14:108,305,343...108,376,618
Ensembl chr14:108,305,418...108,372,157
JBrowse link
G RGD1310429 similar to Protein Njmu-R1 multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of RGD1310429 mRNA CTD PMID:18606552 NCBI chr10:67,738,131...67,751,049
Ensembl chr10:67,739,103...67,751,002
JBrowse link
G Robo2 roundabout guidance receptor 2 multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of ROBO2 mRNA CTD PMID:18606552 NCBI chr11:11,062,866...12,618,793
Ensembl chr11:11,062,790...11,585,765
JBrowse link
G Scube1 signal peptide, CUB domain and EGF like domain containing 1 multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in increased expression of SCUBE1 mRNA CTD PMID:18606552 NCBI chr 7:124,501,988...124,620,755
Ensembl chr 7:124,501,988...124,620,703
JBrowse link
G Senp5 SUMO specific peptidase 5 multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of SENP5 mRNA CTD PMID:18606552 NCBI chr11:72,883,892...72,918,759
Ensembl chr11:72,892,448...72,915,230
JBrowse link
G Slc28a1 solute carrier family 28 member 1 multiple interactions
increases uptake
EXP Zalcitabine inhibits the reaction [SLC28A1 protein results in increased uptake of Uridine]; Zalcitabine promotes the reaction [SLC28A1 protein results in increased export of Uridine]
SLC28A1 protein results in increased uptake of Zalcitabine
CTD PMID:8027026, PMID:8700147, PMID:8713072 NCBI chr 1:142,948,942...142,992,410
Ensembl chr 1:142,950,540...142,992,615
JBrowse link
G Slc29a3 solute carrier family 29 member 3 affects transport ISO SLC29A3 protein affects the transport of Zalcitabine CTD PMID:19164483 NCBI chr20:30,289,527...30,327,343
Ensembl chr20:30,287,424...30,327,361
JBrowse link
G Slc35g2 solute carrier family 35, member G2 multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of SLC35G2 mRNA CTD PMID:18606552 NCBI chr 8:108,854,134...108,881,519
Ensembl chr 8:108,854,146...108,880,879
JBrowse link
G Slc4a8 solute carrier family 4 member 8 multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in increased expression of SLC4A8 mRNA CTD PMID:18606552 NCBI chr 7:142,397,352...142,467,398
Ensembl chr 7:142,397,371...142,464,158
JBrowse link
G St8sia3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of ST8SIA3 mRNA CTD PMID:18606552 NCBI chr18:59,748,766...59,755,257
Ensembl chr18:59,748,444...59,755,226
JBrowse link
G Sv2b synaptic vesicle glycoprotein 2b multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in decreased expression of SV2B mRNA CTD PMID:18606552 NCBI chr 1:136,664,199...136,842,247
Ensembl chr 1:136,664,204...136,842,247
JBrowse link
G Tfam transcription factor A, mitochondrial affects expression ISO Zalcitabine affects the expression of TFAM protein CTD PMID:7849699 NCBI chr20:18,594,057...18,606,106
Ensembl chr20:18,594,037...18,606,151
JBrowse link
G Tk1 thymidine kinase 1 decreases expression ISO Zalcitabine results in decreased expression of TK1 mRNA; Zalcitabine results in decreased expression of TK1 protein CTD PMID:14659972 NCBI chr10:106,817,556...106,828,888
Ensembl chr10:106,817,601...106,828,884
JBrowse link
G Tk2 thymidine kinase 2 decreases expression ISO Zalcitabine results in decreased expression of TK2 mRNA CTD PMID:14659972 NCBI chr19:917,203...939,236
Ensembl chr19:917,203...939,221
JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 increases response to substance EXP TRPV4 protein results in increased susceptibility to Zalcitabine CTD PMID:18234883 NCBI chr12:47,698,915...47,737,902
Ensembl chr12:47,698,947...47,737,902
JBrowse link
G Tymp thymidine phosphorylase increases expression ISO Zalcitabine results in increased expression of TYMP protein CTD PMID:16457948 NCBI chr 7:130,342,481...130,347,845
Ensembl chr 7:130,342,483...130,347,587
JBrowse link
G Vgf VGF nerve growth factor inducible multiple interactions EXP [gp120 protein, Human immunodeficiency virus 1 co-treated with Zalcitabine] results in increased expression of VGF mRNA CTD PMID:18606552 NCBI chr12:22,677,302...22,680,630
Ensembl chr12:22,677,607...22,680,630
JBrowse link
zidovudine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca3 ATP binding cassette subfamily A member 3 increases expression ISO Zidovudine results in increased expression of ABCA3 mRNA CTD PMID:24292225 NCBI chr10:13,723,365...13,780,558
Ensembl chr10:13,723,405...13,779,963
JBrowse link
G Abca7 ATP binding cassette subfamily A member 7 decreases expression
increases expression
ISO Zidovudine results in decreased expression of ABCA7 mRNA
Zidovudine results in increased expression of ABCA7 mRNA
CTD PMID:24292225 NCBI chr 7:12,742,433...12,762,423
Ensembl chr 7:12,742,433...12,762,341
JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 decreases expression EXP Zidovudine results in decreased expression of ABCB11 mRNA CTD PMID:27765674 NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A increases expression ISO Zidovudine results in increased expression of ABCB1 mRNA; Zidovudine results in increased expression of ABCB1 protein CTD PMID:9148857, PMID:15456083, PMID:18310046, PMID:24292225 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcb9 ATP binding cassette subfamily B member 9 increases expression ISO Zidovudine results in increased expression of ABCB9 mRNA CTD PMID:24292225 NCBI chr12:37,923,974...37,956,678
Ensembl chr12:37,923,528...37,958,363
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 increases expression ISO Zidovudine results in increased expression of ABCC1 mRNA CTD PMID:24292225 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcc10 ATP binding cassette subfamily C member 10 increases expression ISO Zidovudine results in increased expression of ABCC10 mRNA CTD PMID:24292225 NCBI chr 9:17,041,351...17,061,263
Ensembl chr 9:17,041,389...17,063,780
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression
decreases expression
ISO
EXP
Zidovudine results in increased expression of ABCC3 mRNA
Zidovudine results in decreased expression of ABCC3 mRNA
CTD PMID:24292225, PMID:27765674 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 affects abundance
increases expression
increases export
ISO ABCC4 protein affects the abundance of Zidovudine
Zidovudine results in increased expression of ABCC4 mRNA
ABCC4 protein results in increased export of Zidovudine
CTD PMID:15456083, PMID:18364470, PMID:18535159 NCBI chr15:103,695,415...103,927,980
Ensembl chr15:103,696,557...103,927,592
JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 increases export
increases expression
ISO ABCC5 protein results in increased export of Zidovudine
Zidovudine results in increased expression of ABCC5 mRNA
CTD PMID:15456083, PMID:18535159, PMID:24292225 NCBI chr11:84,395,982...84,490,215
Ensembl chr11:84,396,033...84,490,211
JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 increases expression ISO Zidovudine results in increased expression of ABCC6 mRNA CTD PMID:24292225 NCBI chr 1:101,954,786...102,013,252
Ensembl chr 1:101,959,540...102,013,243
JBrowse link
G Abcd1 ATP binding cassette subfamily D member 1 increases expression ISO Zidovudine results in increased expression of ABCD1 mRNA CTD PMID:24292225 NCBI chr  X:157,073,860...157,095,652
Ensembl chr  X:157,072,736...157,095,274
JBrowse link
G Abcf2 ATP binding cassette subfamily F member 2 increases expression ISO Zidovudine results in increased expression of ABCF2 mRNA CTD PMID:24292225 NCBI chr 4:7,122,850...7,135,607
Ensembl chr 4:7,122,890...7,135,669
JBrowse link
G Abcf3 ATP binding cassette subfamily F member 3 increases expression ISO Zidovudine results in increased expression of ABCF3 mRNA CTD PMID:24292225 NCBI chr11:84,026,206...84,037,938
Ensembl chr11:84,026,207...84,037,938
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions
increases expression
decreases expression
increases export
decreases export
ISO
EXP
3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in decreased export of Zidovudine]; 3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased export of Zidovudine]; Elacridar inhibits the reaction [ABCG2 protein results in decreased export of Zidovudine]; Elacridar inhibits the reaction [ABCG2 protein results in increased export of Zidovudine]; Nelfinavir inhibits the reaction [ABCG2 protein results in increased export of Zidovudine]; pluronic block copolymer p85 inhibits the reaction [ABCG2 protein results in increased export of Zidovudine]
Zidovudine results in increased expression of ABCG2 protein
Zidovudine results in decreased expression of ABCG2 mRNA
Zidovudine results in increased expression of ABCG2 mRNA
CTD PMID:17437964, PMID:19056916, PMID:24292225, PMID:27765674, PMID:28705594 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 decreases expression EXP Zidovudine results in decreased expression of ABCG8 mRNA CTD PMID:27765674 NCBI chr 6:7,961,413...7,980,708
Ensembl chr 6:7,961,413...7,980,708
JBrowse link
G Acaca acetyl-CoA carboxylase alpha affects expression ISO Zidovudine affects the expression of ACACA mRNA CTD PMID:20032539 NCBI chr10:71,519,392...71,719,910
Ensembl chr10:71,536,533...71,719,910
JBrowse link
G Acacb acetyl-CoA carboxylase beta affects expression ISO Zidovudine affects the expression of ACACB mRNA CTD PMID:20032539 NCBI chr12:48,127,149...48,238,969
Ensembl chr12:48,127,149...48,238,887
JBrowse link
G Acadsb acyl-CoA dehydrogenase, short/branched chain multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ACADSB mRNA CTD PMID:18313992 NCBI chr 1:201,981,362...202,022,771
Ensembl chr 1:201,981,357...202,021,008
JBrowse link
G Acsl6 acyl-CoA synthetase long-chain family member 6 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of ACSL6 mRNA CTD PMID:18313992 NCBI chr10:39,654,771...39,717,592
Ensembl chr10:39,655,455...39,719,312
JBrowse link
G Ada adenosine deaminase increases expression ISO Zidovudine results in increased expression of ADA protein CTD PMID:2261134 NCBI chr 3:160,115,840...160,139,947
Ensembl chr 3:160,115,842...160,139,947
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing decreases expression
multiple interactions
ISO Zidovudine results in decreased expression of ADIPOQ protein
Zidovudine results in decreased expression of ADIPOQ mRNA; Zidovudine results in decreased expression of ADIPOQ protein
[Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of ADIPOQ mRNA
CTD PMID:15865214, PMID:16931933, PMID:17503663, PMID:17668557 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Aebp1 AE binding protein 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of AEBP1 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of AEBP1 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of AEBP1 mRNA CTD PMID:16931933 NCBI chr14:86,101,253...86,111,323
Ensembl chr14:86,101,277...86,111,306
JBrowse link
G Afap1 actin filament associated protein 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of AFAP1 mRNA CTD PMID:15784690 NCBI chr14:79,923,132...80,035,096
Ensembl chr14:79,919,717...79,988,110
JBrowse link
G Agpat3 1-acylglycerol-3-phosphate O-acyltransferase 3 multiple interactions
increases expression
EXP [Zidovudine co-treated with Isoniazid] results in increased expression of AGPAT3 mRNA; Silybin inhibits the reaction [[Zidovudine co-treated with Isoniazid] results in increased expression of AGPAT3 mRNA]
Zidovudine results in increased expression of AGPAT3 mRNA
CTD PMID:28619387 NCBI chr20:11,060,584...11,144,806
Ensembl chr20:11,114,164...11,144,806
JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation EXP Zidovudine results in increased phosphorylation of AKT1 protein CTD PMID:29594326 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Alb albumin affects binding ISO Zidovudine binds to ALB protein CTD PMID:15814459, PMID:16336266 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of ALOX5AP mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of ALOX5AP mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of ALOX5AP mRNA CTD PMID:16931933 NCBI chr12:6,854,930...6,879,112
Ensembl chr12:6,854,920...6,879,154
JBrowse link
G Apoa5 apolipoprotein A5 decreases expression
multiple interactions
EXP Zidovudine results in decreased expression of APOA5 mRNA
[Zidovudine co-treated with Isoniazid] results in decreased expression of APOA5 mRNA; silybin inhibits the reaction [[Zidovudine co-treated with Isoniazid] results in decreased expression of APOA5 mRNA]
CTD PMID:28619387 NCBI chr 8:50,559,079...50,561,720
Ensembl chr 8:50,559,126...50,561,736
JBrowse link
G Aprt adenine phosphoribosyl transferase increases mutagenesis ISO Zidovudine results in increased mutagenesis of APRT gene CTD PMID:10970446 NCBI chr19:55,387,288...55,389,256
Ensembl chr19:55,387,288...55,389,256
JBrowse link
G Aqp9 aquaporin 9 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of AQP9 mRNA
[Zidovudine co-treated with Lamivudine] results in increased expression of AQP9 mRNA
CTD PMID:18313992, PMID:20370541 NCBI chr 8:77,559,621...77,599,781
Ensembl chr 8:77,559,624...77,599,781
JBrowse link
G Arpp21 cAMP regulated phosphoprotein 21 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of ARPP21 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of ARPP21 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of ARPP21 mRNA CTD PMID:16931933 NCBI chr 8:120,323,895...120,492,790
Ensembl chr 8:120,323,897...120,446,507
JBrowse link
G Asic2 acid sensing ion channel subunit 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of ASIC2 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of ASIC2 mRNA CTD PMID:16931933 NCBI chr10:68,247,800...69,347,223
Ensembl chr10:68,248,655...68,517,564
JBrowse link
G Asl argininosuccinate lyase multiple interactions
increases activity
EXP [Isoniazid co-treated with Zidovudine] results in increased activity of ASL protein; silybin inhibits the reaction [[Isoniazid co-treated with Zidovudine] results in increased activity of ASL protein]
Zidovudine results in increased activity of ASL protein
CTD PMID:28619387 NCBI chr12:30,160,922...30,178,348
Ensembl chr12:30,165,694...30,178,341
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ASNS mRNA CTD PMID:15784690 NCBI chr 4:33,742,876...33,761,106
Ensembl chr 4:33,743,364...33,761,163
JBrowse link
G Ass1 argininosuccinate synthase 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ASS1 mRNA CTD PMID:15784690 NCBI chr 3:10,327,411...10,375,847
Ensembl chr 3:10,327,414...10,375,826
JBrowse link
G Atf3 activating transcription factor 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ATF3 mRNA CTD PMID:15784690 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of ATP2A2 mRNA CTD PMID:11706060 NCBI chr12:39,553,903...39,603,326
Ensembl chr12:39,553,903...39,603,326
JBrowse link
G Atp5f1c ATP synthase F1 subunit gamma multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ATP5C1 mRNA CTD PMID:18313992 NCBI chr17:72,209,321...72,231,562
Ensembl chr17:72,209,373...72,394,271
JBrowse link
G Atp5f1d ATP synthase F1 subunit delta decreases expression ISO Zidovudine results in decreased expression of ATP5F1D mRNA CTD PMID:16894629 NCBI chr 7:12,426,807...12,432,120
Ensembl chr 7:12,426,809...12,432,130
JBrowse link
G Atp5mc3 ATP synthase membrane subunit c locus 3 increases expression
multiple interactions
ISO Zidovudine results in increased expression of ATP5MC3 mRNA
[Zidovudine co-treated with Lamivudine] results in decreased expression of ATP5G3 mRNA
CTD PMID:16894629, PMID:18313992 NCBI chr 3:60,811,218...60,813,903
Ensembl chr 3:60,811,210...60,813,869
JBrowse link
G Atp5me ATP synthase membrane subunit e increases expression ISO Zidovudine results in increased expression of ATP5ME mRNA CTD PMID:16894629 NCBI chr14:2,325,308...2,326,436
Ensembl chr14:2,325,308...2,326,436
JBrowse link
G Atp5mf ATP synthase membrane subunit f multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ATP5J2 mRNA CTD PMID:18313992 NCBI chr12:11,191,799...11,198,369
Ensembl chr12:11,191,812...11,198,369
JBrowse link
G Atp5mg ATP synthase membrane subunit g increases expression ISO Zidovudine results in increased expression of ATP5MG mRNA CTD PMID:16894629 NCBI chr 8:49,220,441...49,227,273
Ensembl chr 8:49,220,443...49,227,273
JBrowse link
G Atp5pb ATP synthase peripheral stalk-membrane subunit b increases expression ISO Zidovudine results in increased expression of ATP5PB mRNA CTD PMID:16894629 NCBI chr 2:208,566,385...208,577,147
Ensembl chr 2:208,566,385...208,577,146
JBrowse link
G Atp5pd ATP synthase peripheral stalk subunit d multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ATP5H mRNA CTD PMID:18313992 NCBI chr10:103,967,340...103,972,552
Ensembl chr10:103,967,312...103,972,668
JBrowse link
G Atp5pf ATP synthase peripheral stalk subunit F6 increases expression
multiple interactions
ISO Zidovudine results in increased expression of ATP5PF mRNA
[Zidovudine co-treated with Lamivudine] results in increased expression of ATP5J mRNA
CTD PMID:16894629, PMID:18313992 NCBI chr11:24,286,806...24,294,419
Ensembl chr11:24,286,787...24,294,179
JBrowse link
G Atp5po ATP synthase peripheral stalk subunit OSCP multiple interactions
increases expression
ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of ATP5O mRNA
Zidovudine results in increased expression of ATP5PO mRNA
CTD PMID:16894629, PMID:18313992 NCBI chr11:32,081,606...32,087,918
Ensembl chr11:32,081,574...32,088,002
JBrowse link
G Atp8b1 ATPase phospholipid transporting 8B1 decreases expression ISO Zidovudine results in decreased expression of ATP8B1 mRNA CTD PMID:16894629 NCBI chr18:60,013,388...60,152,920
Ensembl chr18:60,013,382...60,095,354
JBrowse link
G Bcl2 BCL2, apoptosis regulator affects response to substance
increases expression
multiple interactions
decreases expression
ISO
EXP
BCL2 protein affects the susceptibility to Zidovudine
Zidovudine results in increased expression of BCL2 mRNA
[Zidovudine co-treated with Lamivudine] results in decreased expression of BCL2 mRNA
Drugs, Chinese Herbal promotes the reaction [Zidovudine results in decreased expression of BCL2 mRNA]
CTD PMID:9850737, PMID:17696246, PMID:18313992, PMID:29594326 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bnip3l BCL2 interacting protein 3 like increases expression ISO Zidovudine results in increased expression of BNIP3L protein CTD PMID:23640862 NCBI chr15:43,643,897...43,667,123
Ensembl chr15:43,643,897...43,667,029
JBrowse link
G Bst2 bone marrow stromal cell antigen 2 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of BST2 mRNA CTD PMID:20370541 NCBI chr16:19,938,781...19,942,353
Ensembl chr16:19,938,784...19,942,353
JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO Zidovudine results in increased expression of BTG2 mRNA CTD PMID:23675285 NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982
JBrowse link
G C1r complement C1r multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of C1R mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of C1R mRNA CTD PMID:16931933 NCBI chr 4:157,126,060...157,136,825
Ensembl chr 4:157,125,998...157,136,829
JBrowse link
G C3ar1 complement C3a receptor 1 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of C3AR1 mRNA
[Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of C3AR1 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of C3AR1 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of C3AR1 mRNA
CTD PMID:16931933, PMID:20370541 NCBI chr 4:155,681,767...155,691,240
Ensembl chr 4:155,684,029...155,690,869
JBrowse link
G Cars cysteinyl-tRNA synthetase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of CARS1 mRNA CTD PMID:15784690 NCBI chr 1:216,759,367...216,801,652
Ensembl chr 1:216,759,366...216,801,656
JBrowse link
G Casp3 caspase 3 multiple interactions
increases cleavage
increases expression
increases activity
ISO [Acrolein co-treated with Zidovudine] results in increased cleavage of CASP3 protein; Drugs, Chinese Herbal promotes the reaction [Zidovudine results in increased expression of CASP3 mRNA]
Zidovudine results in increased cleavage of CASP3 protein
Zidovudine results in increased expression of CASP3 protein
Zidovudine results in increased activity of CASP3 protein
2,6-dimethyl-3,5-bis(2'-propoxyethoxycarbonyl)-4-(2''-difluoromethoxyphenyl)-1,4-dihydropyridine inhibits the reaction [Zidovudine results in increased expression of CASP3 protein]; glutapyrone inhibits the reaction [Zidovudine results in increased expression of CASP3 protein]; tauropyrone inhibits the reaction [Zidovudine results in increased expression of CASP3 protein]
CTD PMID:16601281, PMID:17696246, PMID:17943461, PMID:18801031, PMID:27238871 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 increases cleavage
multiple interactions
ISO Zidovudine results in increased cleavage of CASP8 protein
Acrolein promotes the reaction [Zidovudine results in increased cleavage of CASP8 protein]; Zidovudine promotes the reaction [Acrolein results in increased cleavage of CASP8 protein]
CTD PMID:27238871 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Cat catalase decreases response to substance ISO CAT protein results in decreased susceptibility to Zidovudine CTD PMID:19398959 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO Zidovudine results in increased expression of CCL2 protein CTD PMID:17668557 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccna2 cyclin A2 multiple interactions
decreases expression
ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of CCNA2 mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of CCNA2 mRNA
Zidovudine results in decreased expression of CCNA2 mRNA
CTD PMID:15784690, PMID:20370541 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214
JBrowse link
G Ccnb1 cyclin B1 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of CCNB1 mRNA CTD PMID:20370541 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Ccnc cyclin C multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CCNC mRNA CTD PMID:15784690 NCBI chr 5:35,865,598...35,883,732
Ensembl chr 5:35,865,605...35,883,706
JBrowse link
G Ccnd1 cyclin D1 multiple interactions
increases expression
ISO [Zidovudine co-treated with Lamivudine] results in increased expression of CCND1 mRNA
Zidovudine results in increased expression of CCND1 mRNA
CTD PMID:15784690 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccnd2 cyclin D2 multiple interactions
decreases expression
ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CCND2 mRNA
Zidovudine results in decreased expression of CCND2 mRNA
CTD PMID:15784690 NCBI chr 4:159,674,885...159,697,207
Ensembl chr 4:159,674,885...159,697,207
JBrowse link
G Ccne2 cyclin E2 decreases expression
multiple interactions
ISO Zidovudine results in decreased expression of CCNE2 mRNA
[Zidovudine co-treated with Lamivudine] results in decreased expression of CCNE2 mRNA
CTD PMID:15784690 NCBI chr 5:24,434,077...24,446,406
Ensembl chr 5:24,434,872...24,446,406
JBrowse link
G Ccnl2 cyclin L2 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of CCNL2 mRNA CTD PMID:20370541 NCBI chr 5:173,256,301...173,268,279
Ensembl chr 5:173,256,637...173,276,169
JBrowse link
G Ccr5 C-C motif chemokine receptor 5 multiple interactions ISO [Zidovudine co-treated with IFNA1 protein] results in increased expression of CCR5 mRNA CTD PMID:20370541 NCBI chr 8:133,192,398...133,215,599
Ensembl chr 8:133,197,032...133,215,614
JBrowse link