Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:4-tolyl isocyanate
go back to main search page
Accession:CHEBI:53732 term browser browse the term
Definition:An isocyanate comprising a benzene core with isocyanato and methyl substituents para to each other.
Synonyms:exact_synonym: 1-isocyanato-4-methylbenzene
 related_synonym: 4-Isocyanatotoluene;   4-Methylphenyl isocyanate;   4-Tol-NCO;   Formula=C8H7NO;   InChI=1S/C8H7NO/c1-7-2-4-8(5-3-7)9-6-10/h2-5H,1H3;   InChIKey=MGYGFNQQGAQEON-UHFFFAOYSA-N;   Isocyanic acid, p-tolyl ester;   PTI;   SMILES=Cc1ccc(cc1)N=C=O;   TMI;   p-Isocyanatotoluene;   p-Methylphenyl isocyanate;   p-TMI;   p-Toluene isocyanate;   p-Tolyl isocyanate;   p-tolylmonoisocyanate;   para-tolyl monoisocyanate
 xref: Beilstein:471494;   CAS:622-58-2
 xref_mesh: MESH:C025637
 xref: PMID:211841;   PMID:21878336;   PMID:24553658;   PMID:2979745;   PMID:3810654;   PMID:4037253;   PMID:6268767;   PMID:6296214;   PMID:6299614;   PMID:6821040;   Reaxys:471494


show annotations for term's descendants           Sort by:
 
4-tolyl isocyanate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il10 interleukin 10 increases expression ISO 4-tolyl isocyanate results in increased expression of IL10 mRNA CTD PMID:15664275 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il13 interleukin 13 increases expression ISO 4-tolyl isocyanate results in increased expression of IL13 mRNA CTD PMID:15664275 NCBI chr10:38,982,909...38,985,466
Ensembl chr10:38,982,909...38,985,466
JBrowse link
G Il2 interleukin 2 increases expression ISO 4-tolyl isocyanate results in increased expression of IL2 protein CTD PMID:22381623 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il4 interleukin 4 increases expression ISO 4-tolyl isocyanate results in increased expression of IL4 mRNA; 4-tolyl isocyanate results in increased expression of IL4 protein CTD PMID:15664275, PMID:22381623 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il4r interleukin 4 receptor increases expression ISO 4-tolyl isocyanate results in increased expression of IL4RA protein CTD PMID:22381623 NCBI chr 1:196,942,343...196,967,221
Ensembl chr 1:196,942,364...196,967,220
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19810
    role 19758
      biological role 19758
        hapten 3013
          4-tolyl isocyanate 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    p-block element atom 19696
                      carbon group element atom 19599
                        carbon atom 19588
                          organic molecular entity 19588
                            organic molecule 19514
                              organic cyclic compound 19311
                                carbocyclic compound 18219
                                  benzenoid aromatic compound 17254
                                    benzenes 17011
                                      toluenes 6238
                                        4-tolyl isocyanate 5
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.