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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:53619 term browser browse the term
Definition:A diamine in which the two amino groups are substituted into toluene at the 2- and 5-positions.
Synonyms:exact_synonym: 2-methylbenzene-1,4-diamine
 related_synonym: 1-methyl-2,5-diaminobenzene;   2,5-Diaminotoluene;   2,5-Toluenediamine;   2,5-diamino-1-methylbenzene;   2-Methyl-1,4-benzenediamine;   4-Amino-2-methylaniline;   Formula=C7H10N2;   InChI=1S/C7H10N2/c1-5-4-6(8)2-3-7(5)9/h2-4H,8-9H2,1H3;   InChIKey=OBCSAIDCZQSFQH-UHFFFAOYSA-N;   SMILES=Cc1cc(N)ccc1N;   p-Toluenediamine;   toluene-2,5-diamine
 xref: Beilstein:774521;   CAS:95-70-5;   KEGG:C19386
 xref_mesh: MESH:C007303
 xref: PMID:18844695;   Reaxys:774521

show annotations for term's descendants           Sort by:
2-methyl-1,4-phenylenediamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp3 aquaporin 3 (Gill blood group) decreases expression ISO 2,5-diaminotoluene results in decreased expression of AQP3 mRNA CTD PMID:15140218 NCBI chr 5:57,423,735...57,429,252
Ensembl chr 5:57,423,734...57,429,245
JBrowse link
G Il1b interleukin 1 beta increases expression ISO 2,5-diaminotoluene results in increased expression of IL1B mRNA CTD PMID:15140218 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19883
    role 19833
      chemical role 19351
        fuel additive 3083
          toluene 3073
            2-methyl-1,4-phenylenediamine 2
              2,5-diaminotoluene sulfate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19883
    subatomic particle 19881
      composite particle 19881
        hadron 19881
          baryon 19881
            nucleon 19881
              atomic nucleus 19881
                atom 19881
                  main group element atom 19771
                    main group molecular entity 19771
                      s-block molecular entity 19520
                        hydrogen molecular entity 19512
                          hydrides 18784
                            organic hydride 18338
                              organic fundamental parent 18338
                                hydrocarbon 18064
                                  cyclic hydrocarbon 17117
                                    monocyclic hydrocarbon 5807
                                      annulene 5633
                                        aromatic annulene 5633
                                          benzene 5633
                                            alkylbenzene 3350
                                              methylbenzene 3210
                                                toluene 3073
                                                  2-methyl-1,4-phenylenediamine 2
                                                    2,5-diaminotoluene sulfate 0
paths to the root