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Accession:CHEBI:5353 term browser browse the term
Definition:A biflavonoid that is the 7,4'-dimethyl ether derivative of amentoflavone. Isolated from Ginkgo biloba and Dioon, it exhibits anti-HSV-1, antineoplastic and inhibitory activities towards arachidonate 5-lipoxygenase and cyclooxygenase 2.
Synonyms:exact_synonym: 5,7-dihydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxo-4H-chromen-2-yl)-2-methoxyphenyl]-2-(4-hydroxyphenyl)-4H-chromen-4-one
 related_synonym: 4''',5,5'',7''-tetrahydroxy-4',7-dimethoxy-(3'->8'')-biflavone;   5,7-dihydroxy-8-(5-(5-hydroxy-7-methoxy-4-oxo-4H-1-benzopyran-2-yl)-2-methoxyphenyl)-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one;   Amentoflavone 7,4'-dimethyl ether;   Formula=C32H22O10;   InChI=1S/C32H22O10/c1-39-18-10-20(34)30-23(37)13-27(41-28(30)11-18)16-5-8-25(40-2)19(9-16)29-21(35)12-22(36)31-24(38)14-26(42-32(29)31)15-3-6-17(33)7-4-15/h3-14,33-36H,1-2H3;   InChIKey=AIFCFBUSLAEIBR-UHFFFAOYSA-N;   SMILES=COc1cc(O)c2c(c1)oc(cc2=O)-c1ccc(OC)c(c1)-c1c(O)cc(O)c2c1oc(cc2=O)-c1ccc(O)cc1
 alt_id: CHEBI:65965
 xref: CAS:481-46-9 "ChemIDplus";   CAS:481-46-9 "KEGG COMPOUND";   KEGG:C10048;   KNApSAcK:C00001044;   LINCS:LSM-42758;   LIPID_MAPS_instance:LMPK12040003 "LIPID MAPS"
 xref_mesh: MESH:C077458
 xref: PMID:1329635 "Europe PMC";   PMID:16327145 "Europe PMC";   PMID:9134745 "Europe PMC";   Reaxys:381052 "Reaxys"

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ginkgetin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:6480464
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Ftl1 ferritin light chain 1 JBrowse link 1 101,448,190 101,450,034 RGD:6480464
G Tfrc transferrin receptor JBrowse link 11 71,397,423 71,419,263 RGD:6480464
G Th tyrosine hydroxylase JBrowse link 1 216,073,034 216,080,287 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      biological role 19611
        biochemical role 19138
          metabolite 19106
            ginkgetin 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    p-block element atom 19545
                      carbon group element atom 19428
                        carbon atom 19420
                          organic molecular entity 19420
                            organic molecule 19343
                              organic cyclic compound 19093
                                organic heterocyclic compound 18157
                                  oxacycle 16945
                                    benzopyran 9428
                                      1-benzopyran 9120
                                        flavonoid 6242
                                          flavones 4145
                                            hydroxyflavone 4134
                                              amentoflavone 26
                                                ginkgetin 6
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.