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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:all-cis-docosa-7,10,13,16-tetraenoic acid
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Accession:CHEBI:53487 term browser browse the term
Definition:The all-cis-isomer of a C22 polyunsaturated fatty acid having four double bonds in the 7-, 10-, 13- and 16-positions. One of the most abundant fatty acids in the early human brain.
Synonyms:related_synonym: (7Z,10Z,13Z,16Z)-Docosa-7,10,13,16-tetraenoic acid;   7,10,13,16-Docosatetraenoic acid;   7Z,10Z,13Z,16Z-docosatetraenoic acid;   Formula=C22H36O2;   InChI=1S/C22H36O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22(23)24/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-21H2,1H3,(H,23,24)/b7-6-,10-9-,13-12-,16-15-;   InChIKey=TWSWSIQAPQLDBP-DOFZRALJSA-N;   SMILES=CCCCC\\C=C/C\\C=C/C\\C=C/C\\C=C/CCCCCC(O)=O;   adrenic acid;   all-cis-7,10,13,16-docosatetraenoic acid;   cis,cis,cis,cis-Docosa-7,10,13,16-tetraensaeure
 xref: Beilstein:1914611;   CAS:28874-58-0;   HMDB:HMDB0002226;   KEGG:C16527;   LIPID_MAPS_instance:LMFA01030178
 xref_mesh: MESH:C011395
 xref: PMID:11971947;   PMID:1532827;   PMID:17291553;   PMID:2538146;   PMID:3021726;   Reaxys:1914611;   Wikipedia:Adrenic_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:77225

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all-cis-docosa-7,10,13,16-tetraenoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rxra retinoid X receptor alpha multiple interactions ISO adrenic acid binds to and results in increased activity of RXRA protein CTD PMID:16258897 NCBI chr 3:6,272,560...6,295,354
Ensembl chr 3:6,211,789...6,295,908 		JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO [TP53 protein mutant form results in increased susceptibility to Niclosamide] which results in increased abundance of adrenic acid CTD PMID:30258081 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19853
    role 19804
      biological role 19804
        biochemical role 19339
          metabolite 19319
            eukaryotic metabolite 18976
              algal metabolite 13636
                all-cis-docosa-7,10,13,16-tetraenoic acid 2
                  (7Z,10Z,13Z,16Z)-docosatetraenoyl group 0
                  (7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA 0
                  (7Z,10Z,13Z,16Z)-docosatetraenoyl-containing glycerolipid 0
                  1,2-di-(7Z,10Z,13Z,16Z-docosatetraenoyl)-sn-glycerol 0
                  1-(all-cis-docosa-7,10,13,16-tetraenoyl)glycerol 0
                  1-[(7Z,10Z,13Z,16Z)-docosatetraenoyl]-2-octadecanoyl-sn-glycero-3-phosphocholine 0
                  1-[(7Z,10Z,13Z,16Z)-docosatetraenoyl]-sn-glycero-3-phosphocholine 0
                  1-[(9Z)-octadecenoyl]-2-[(7Z,10Z,13Z,16Z)-docosatetraenoyl]-sn-glycero-3-phosphocholine 0
                  1-hexadecanoyl-2-[(7Z,10Z,13Z,16Z)-docosatetraenoyl]-sn-glycero-3-phosphocholine 0
                  1-icosyl-2-[(7Z,10Z,13Z,16Z)-docosatetraenoyl]-sn-glycero-3-phosphocholine 0
                  1-octadecanoyl-2-(7Z,10Z,13Z,16Z-docosatetraenoyl)-sn-glycero-3-phosphocholine 0
                  1-octadecyl-2-[(7Z,10Z,13Z,16Z)-docosatetraenoyl]-sn-glycero-3-phosphocholine 0
                  1-oleoyl-2-(7Z,10Z,13Z,16Z-docosatetraenoyl)-sn-glycerol 0
                  1-palmitoyl-2-(7Z,10Z,13Z,16Z-docosatetraenoyl)-sn-glycero-3-phosphoethanolamine 0
                  1-palmitoyl-2-(7Z,10Z,13Z,16Z-docosatetraenoyl)-sn-glycerol 0
                  1-stearoyl-2-(7Z,10Z,13Z,16Z-docosatetraenoyl)-sn-glycero-3-phosphoserine 0
                  1-stearoyl-2-(7Z,10Z,13Z,16Z-docosatetraenoyl)-sn-glycerol 0
                  CE(22:4(7Z,10Z,13Z,16Z)) 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19853
    subatomic particle 19851
      composite particle 19851
        hadron 19851
          baryon 19851
            nucleon 19851
              atomic nucleus 19851
                atom 19851
                  main group element atom 19744
                    p-block element atom 19744
                      carbon group element atom 19650
                        carbon atom 19639
                          organic molecular entity 19639
                            organic group 18550
                              organic divalent group 18541
                                organodiyl group 18541
                                  carbonyl group 18447
                                    carbonyl compound 18447
                                      carboxylic acid 18125
                                        monocarboxylic acid 17494
                                          fatty acid 15997
                                            unsaturated fatty acid 939
                                              polyunsaturated fatty acid 677
                                                essential fatty acid 394
                                                  omega-6 fatty acid 387
                                                    all-cis-docosa-7,10,13,16-tetraenoic acid 2
                                                      (7Z,10Z,13Z,16Z)-docosatetraenoyl group 0
                                                      (7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA 0
                                                      (7Z,10Z,13Z,16Z)-docosatetraenoyl-containing glycerolipid 0
                                                      1,2-di-(7Z,10Z,13Z,16Z-docosatetraenoyl)-sn-glycerol 0
                                                      1-(all-cis-docosa-7,10,13,16-tetraenoyl)glycerol 0
                                                      1-[(7Z,10Z,13Z,16Z)-docosatetraenoyl]-2-octadecanoyl-sn-glycero-3-phosphocholine 0
                                                      1-[(7Z,10Z,13Z,16Z)-docosatetraenoyl]-sn-glycero-3-phosphocholine 0
                                                      1-[(9Z)-octadecenoyl]-2-[(7Z,10Z,13Z,16Z)-docosatetraenoyl]-sn-glycero-3-phosphocholine 0
                                                      1-hexadecanoyl-2-[(7Z,10Z,13Z,16Z)-docosatetraenoyl]-sn-glycero-3-phosphocholine 0
                                                      1-icosyl-2-[(7Z,10Z,13Z,16Z)-docosatetraenoyl]-sn-glycero-3-phosphocholine 0
                                                      1-octadecanoyl-2-(7Z,10Z,13Z,16Z-docosatetraenoyl)-sn-glycero-3-phosphocholine 0
                                                      1-octadecyl-2-[(7Z,10Z,13Z,16Z)-docosatetraenoyl]-sn-glycero-3-phosphocholine 0
                                                      1-oleoyl-2-(7Z,10Z,13Z,16Z-docosatetraenoyl)-sn-glycerol 0
                                                      1-palmitoyl-2-(7Z,10Z,13Z,16Z-docosatetraenoyl)-sn-glycero-3-phosphoethanolamine 0
                                                      1-palmitoyl-2-(7Z,10Z,13Z,16Z-docosatetraenoyl)-sn-glycerol 0
                                                      1-stearoyl-2-(7Z,10Z,13Z,16Z-docosatetraenoyl)-sn-glycero-3-phosphoserine 0
                                                      1-stearoyl-2-(7Z,10Z,13Z,16Z-docosatetraenoyl)-sn-glycerol 0
                                                      CE(22:4(7Z,10Z,13Z,16Z)) 0
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