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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:beryllium sulfate
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Accession:CHEBI:53473 term browser browse the term
Definition:A metal sulfate in which the metal is beryllium (in the +2 oxidation state) and the ratio of beryllium to sulfate is 1:1.
Synonyms:related_synonym: BeSO4;   Beryllium sulphate;   Formula=BeO4S;   InChI=1S/Be.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2;   InChIKey=KQHXBDOEECKORE-UHFFFAOYSA-L;   SMILES=[Be++].[O-]S([O-])(=O)=O;   beryllium(II) sulfate
 xref: CAS:13510-49-1;   Gmelin:8296
 xref_mesh: MESH:C020711
 xref: PMID:11207315;   PMID:11423174;   PMID:11678613;   PMID:11897645;   PMID:16951350;   PMID:18250483;   PMID:18768897;   PMID:20549306;   PMID:2179717;   PMID:2469014;   PMID:2930060;   PMID:2954196;   PMID:3498695;   PMID:3764912;   PMID:3824419;   PMID:7122994;   PMID:8991630;   Patent:US4316840;   Patent:US4394524;   Patent:US5436364;   Reaxys:13316867;   Wikipedia:Beryllium_sulfate


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beryllium sulfate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTA2 actin alpha 2, smooth muscle increases expression EXP beryllium sulfate results in increased expression of ACTA2 mRNA CTD PMID:16314022 NCBI chr10:88,935,074...88,991,397
Ensembl chr10:88,935,074...88,991,339
JBrowse link
G ANXA5 annexin A5 increases expression EXP beryllium sulfate results in increased expression of ANXA5 mRNA CTD PMID:16314022 NCBI chr 4:121,667,946...121,696,994
Ensembl chr 4:121,667,946...121,696,995
JBrowse link
G CCL3 C-C motif chemokine ligand 3 multiple interactions
increases secretion
EXP beryllium sulfate promotes the reaction [RUNX1 protein binds to CCL3 promoter]
beryllium sulfate results in increased secretion of CCL3 mRNA
CTD PMID:16314022 NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169
JBrowse link
G CCL4 C-C motif chemokine ligand 4 increases secretion EXP beryllium sulfate results in increased secretion of CCL4 mRNA CTD PMID:16314022 NCBI chr17:36,103,827...36,105,614
Ensembl chr17:36,103,827...36,105,621
JBrowse link
G CCL5 C-C motif chemokine ligand 5 increases expression EXP beryllium sulfate results in increased expression of CCL5 mRNA CTD PMID:16314022 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793
JBrowse link
G CD44 CD44 molecule (Indian blood group) increases expression EXP beryllium sulfate results in increased expression of CD44 mRNA CTD PMID:16314022 NCBI chr11:35,139,168...35,232,402
Ensembl chr11:35,138,882...35,232,402
Ensembl chr11:35,138,882...35,232,402
JBrowse link
G CD86 CD86 molecule increases expression EXP beryllium sulfate results in increased expression of CD86 protein CTD PMID:19665512 NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A multiple interactions
increases expression
EXP beryllium sulfate promotes the reaction [TP53 protein binds to CDKN1A promoter]
beryllium sulfate results in increased expression of CDKN1A mRNA; beryllium sulfate results in increased expression of CDKN1A protein
CTD PMID:17395767 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,339
Ensembl chr 6:36,676,460...36,687,339
JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A increases expression EXP beryllium sulfate results in increased expression of CDKN2A mRNA; beryllium sulfate results in increased expression of CDKN2A protein CTD PMID:17395767 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,753...21,995,301
JBrowse link
G CREB1 cAMP responsive element binding protein 1 multiple interactions ISO [beryllium sulfate co-treated with IFNG protein] results in increased expression of CREB1 protein CTD PMID:10755711 NCBI chr 2:207,529,943...207,605,988
Ensembl chr 2:207,529,737...207,605,988
JBrowse link
G CTSL cathepsin L increases expression EXP beryllium sulfate results in increased expression of CTSL mRNA CTD PMID:16314022 NCBI chr 9:87,726,119...87,731,469
Ensembl chr 9:87,726,109...87,731,469
JBrowse link
G CTSV cathepsin V increases expression EXP beryllium sulfate results in increased expression of CTSV mRNA CTD PMID:16314022 NCBI chr 9:97,029,677...97,039,643
Ensembl chr 9:97,029,677...97,039,643
JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 increases secretion EXP beryllium sulfate results in increased secretion of CXCL1 mRNA CTD PMID:16314022 NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308
JBrowse link
G CXCL3 C-X-C motif chemokine ligand 3 increases expression EXP beryllium sulfate results in increased expression of CXCL3 mRNA CTD PMID:16314022 NCBI chr 4:74,036,589...74,038,689
Ensembl chr 4:74,036,589...74,038,807
JBrowse link
G EGR2 early growth response 2 increases expression EXP beryllium sulfate results in increased expression of EGR2 mRNA CTD PMID:16314022 NCBI chr10:62,811,996...62,819,167
Ensembl chr10:62,811,996...62,919,900
JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
ISO beryllium sulfate results in increased expression of FOS mRNA
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [beryllium sulfate results in increased expression of FOS mRNA]; Dactinomycin inhibits the reaction [beryllium sulfate results in increased expression of FOS mRNA]; Ro 31-8220 inhibits the reaction [beryllium sulfate results in increased expression of FOS mRNA]
CTD PMID:11568973 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230
JBrowse link
G HLA-A major histocompatibility complex, class I, A increases expression EXP beryllium sulfate results in increased expression of HLA-A mRNA CTD PMID:16314022 NCBI chr 6:29,942,532...29,945,870
Ensembl chr 6:29,941,260...29,945,884
JBrowse link
G HLA-C major histocompatibility complex, class I, C increases expression EXP beryllium sulfate results in increased expression of HLA-C mRNA CTD PMID:16314022 NCBI chr 6:31,268,749...31,272,092
Ensembl chr 6:31,268,749...31,272,130
JBrowse link
G HLA-DPB1 major histocompatibility complex, class II, DP beta 1 affects binding EXP beryllium sulfate binds to HLA-DPB1 protein CTD PMID:11423174 NCBI chr 6:33,075,990...33,089,696
Ensembl chr 6:33,075,990...33,089,696
JBrowse link
G HLA-DPB2 major histocompatibility complex, class II, DP beta 2 (pseudogene) increases response to substance EXP HLA-DPB2 protein mutant form results in increased susceptibility to beryllium sulfate CTD PMID:16272364 NCBI chr 6:33,112,516...33,129,113
Ensembl chr 6:33,112,451...33,129,084
JBrowse link
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 increases response to substance
increases expression
EXP HLA-DRB1 protein mutant form results in increased susceptibility to beryllium sulfate
beryllium sulfate results in increased expression of HLA-DRB1 mRNA
CTD PMID:16272364, PMID:16314022 NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,578,769...32,589,848
JBrowse link
G HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 increases expression EXP beryllium sulfate results in increased expression of HNRNPA1 mRNA CTD PMID:16314022 NCBI chr12:54,280,726...54,287,087
Ensembl chr12:54,280,193...54,287,088
JBrowse link
G ICAM1 intercellular adhesion molecule 1 multiple interactions
increases secretion
increases expression
EXP 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [beryllium sulfate results in increased expression of ICAM1 mRNA]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [beryllium sulfate results in increased secretion of ICAM1 protein]; Dimethyl Sulfoxide inhibits the reaction [beryllium sulfate results in increased secretion of ICAM1 protein]
beryllium sulfate results in increased expression of ICAM1 mRNA; beryllium sulfate results in increased expression of ICAM1 protein
CTD PMID:18539414 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
JBrowse link
G IFNG interferon gamma increases expression
multiple interactions
EXP
ISO
beryllium sulfate results in increased expression of IFNG protein
[beryllium sulfate co-treated with IFNG protein] results in increased expression of CREB1 protein; [beryllium sulfate co-treated with IFNG protein] results in increased expression of JUN protein; [beryllium sulfate co-treated with IFNG protein] results in increased expression of JUNB protein; [beryllium sulfate co-treated with IFNG protein] results in increased expression of NFKB1 protein; beryllium sulfate promotes the reaction [IFNG protein results in increased expression of TNF protein]
CTD PMID:10755710, PMID:10755711, PMID:20974702 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G IL18 interleukin 18 increases expression EXP beryllium sulfate results in increased expression of IL18 mRNA; beryllium sulfate results in increased expression of IL18 protein CTD PMID:16100009 NCBI chr11:112,143,251...112,164,104
Ensembl chr11:112,143,253...112,164,096
JBrowse link
G IL2 interleukin 2 increases expression ISO beryllium sulfate results in increased expression of IL2 mRNA CTD PMID:9328138 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725
JBrowse link
G IL5 interleukin 5 increases expression ISO beryllium sulfate results in increased expression of IL5 mRNA CTD PMID:9328138 NCBI chr 5:132,539,194...132,556,864
Ensembl chr 5:132,541,445...132,556,838
JBrowse link
G IL6 interleukin 6 increases expression ISO beryllium sulfate results in increased expression of IL6 mRNA CTD PMID:9328138 NCBI chr 7:22,725,889...22,732,002
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G ITGB3 integrin subunit beta 3 increases expression EXP beryllium sulfate results in increased expression of ITGB3 mRNA CTD PMID:16314022 NCBI chr17:47,253,827...47,313,743
Ensembl chr17:47,253,846...47,313,735
Ensembl chr17:47,253,846...47,313,735
Ensembl chr17:47,253,846...47,313,735
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [beryllium sulfate results in increased expression of JUN mRNA]; [beryllium sulfate co-treated with IFNG protein] results in increased expression of JUN protein; Dactinomycin inhibits the reaction [beryllium sulfate results in increased expression of JUN mRNA]; Ro 31-8220 inhibits the reaction [beryllium sulfate results in increased expression of JUN mRNA] CTD PMID:10755711, PMID:11568973 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,780,791...58,784,047
JBrowse link
G JUNB JunB proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [beryllium sulfate co-treated with IFNG protein] results in increased expression of JUNB protein CTD PMID:10755711 NCBI chr19:12,791,486...12,793,315
Ensembl chr19:12,791,486...12,793,315
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor increases expression ISO beryllium sulfate results in increased expression of MYC protein CTD PMID:2009323 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
JBrowse link
G NEDD8 NEDD8 ubiquitin like modifier increases expression EXP beryllium sulfate results in increased expression of NEDD8 mRNA CTD PMID:16314022 NCBI chr14:24,216,857...24,232,367
Ensembl chr14:24,216,857...24,232,367
JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 multiple interactions ISO [beryllium sulfate co-treated with IFNG protein] results in increased expression of NFKB1 protein CTD PMID:10755711 NCBI chr 4:102,501,266...102,617,302
Ensembl chr 4:102,501,331...102,617,302
JBrowse link
G NOVA1 NOVA alternative splicing regulator 1 increases expression EXP beryllium sulfate results in increased expression of NOVA1 mRNA CTD PMID:16314022 NCBI chr14:26,443,090...26,598,033
Ensembl chr14:26,443,090...26,598,033
JBrowse link
G RHOA ras homolog family member A increases expression EXP beryllium sulfate results in increased expression of RHOA mRNA CTD PMID:16314022 NCBI chr 3:49,359,145...49,411,976
Ensembl chr 3:49,359,145...49,412,998
JBrowse link
G RPL22 ribosomal protein L22 increases expression EXP beryllium sulfate results in increased expression of RPL22 mRNA CTD PMID:16314022 NCBI chr 1:6,185,020...6,199,595
Ensembl chr 1:6,185,020...6,209,389
JBrowse link
G RPL30 ribosomal protein L30 increases expression EXP beryllium sulfate results in increased expression of RPL30 mRNA CTD PMID:16314022 NCBI chr 8:98,041,721...98,045,545
Ensembl chr 8:98,024,851...98,046,469
JBrowse link
G RPL37A ribosomal protein L37a increases expression EXP beryllium sulfate results in increased expression of RPL37A mRNA CTD PMID:16314022 NCBI chr 2:216,498,844...216,504,086
Ensembl chr 2:216,498,825...216,579,180
JBrowse link
G RPS7 ribosomal protein S7 increases expression EXP beryllium sulfate results in increased expression of RPS7 mRNA CTD PMID:16314022 NCBI chr 2:3,575,260...3,580,920
Ensembl chr 2:3,575,260...3,580,920
JBrowse link
G RUNX1 RUNX family transcription factor 1 multiple interactions EXP beryllium sulfate promotes the reaction [RUNX1 protein binds to CCL3 promoter] CTD PMID:16314022 NCBI chr21:34,787,801...35,049,334
Ensembl chr21:34,787,801...36,004,667
JBrowse link
G SERPINB2 serpin family B member 2 increases expression EXP beryllium sulfate results in increased expression of SERPINB2 mRNA CTD PMID:16314022 NCBI chr18:63,887,705...63,903,890
Ensembl chr18:63,871,692...63,903,888
JBrowse link
G SFTPD surfactant protein D increases expression EXP beryllium sulfate results in increased expression of SFTPD mRNA CTD PMID:16314022 NCBI chr10:79,937,740...79,982,236
Ensembl chr10:79,937,740...79,982,614
JBrowse link
G TAT tyrosine aminotransferase multiple interactions ISO beryllium sulfate inhibits the reaction [Hydrocortisone results in increased expression of TAT protein] CTD PMID:6120038 NCBI chr16:71,565,660...71,577,092
Ensembl chr16:71,565,660...71,577,092
JBrowse link
G TMSB4X thymosin beta 4 X-linked increases expression EXP beryllium sulfate results in increased expression of TMSB4X mRNA CTD PMID:16314022 NCBI chr  X:12,975,110...12,977,223
Ensembl chr  X:12,975,110...12,977,227
JBrowse link
G TNF tumor necrosis factor increases expression
multiple interactions
ISO beryllium sulfate results in increased expression of TNF mRNA; beryllium sulfate results in increased expression of TNF protein
beryllium sulfate promotes the reaction [IFNG protein results in increased expression of TNF protein]
CTD PMID:10755710, PMID:10755711 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TP53 tumor protein p53 multiple interactions
increases expression
EXP beryllium sulfate promotes the reaction [TP53 protein binds to CDKN1A promoter]
beryllium sulfate results in increased expression of TP53 protein
CTD PMID:17395767, PMID:20974702 NCBI chr17:7,668,402...7,687,550
Ensembl chr17:7,661,779...7,687,538
Ensembl chr17:7,661,779...7,687,538
JBrowse link
G WNT4 Wnt family member 4 increases expression EXP beryllium sulfate results in increased expression of WNT4 mRNA CTD PMID:16314022 NCBI chr 1:22,117,308...22,143,981
Ensembl chr 1:22,117,313...22,143,969
JBrowse link
G ZNF77 zinc finger protein 77 increases expression EXP beryllium sulfate results in increased expression of ZNF77 mRNA CTD PMID:16314022 NCBI chr19:2,933,218...2,944,971
Ensembl chr19:2,933,218...2,944,971
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 24374
    role 24282
      biological role 24249
        aetiopathogenetic role 23036
          allergen 18435
            beryllium sulfate 49
              beryllium sulfate tetrahydrate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 24374
    subatomic particle 24331
      composite particle 24331
        hadron 24331
          baryon 24331
            nucleon 24331
              atomic nucleus 24331
                atom 24331
                  main group element atom 24177
                    p-block element atom 24177
                      chalcogen 23204
                        oxygen atom 23077
                          oxygen molecular entity 23077
                            hydroxides 22319
                              oxoacid 21451
                                chalcogen oxoacid 12216
                                  sulfur oxoacid 11779
                                    sulfuric acid 8485
                                      sulfuric acid derivative 8485
                                        sulfates 8482
                                          sulfate salt 7495
                                            inorganic sulfate salt 7439
                                              metal sulfate 7438
                                                beryllium sulfate 49
                                                  beryllium sulfate tetrahydrate 0
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