Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:cobalt(2+) sulfate
go back to main search page
Accession:CHEBI:53470 term browser browse the term
Definition:A compound of cobalt and sulfate in which the ratio of cobalt (+2 oxidation state) to sulfate is 1:1.
Synonyms:related_synonym: CoSO4;   Cobalt Brown;   Cobalt monosulfate;   Cobalt sulfate;   Cobalt(II) sulfate;   Cobaltous sulfate;   Formula=CoO4S;   InChI=1S/Co.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2;   InChIKey=KTVIXTQDYHMGHF-UHFFFAOYSA-L;   SMILES=[Co++].[O-]S([O-])(=O)=O
 xref: CAS:10026-24-1;   CAS:10124-43-3;   Gmelin:268815;   Gmelin:270126;   Gmelin:270959;   Gmelin:8292;   KEGG:C17383;   KEGG:C19215
 xref_mesh: MESH:C026305
 xref: PMID:2415590


show annotations for term's descendants           Sort by:
cobalt(2+) sulfate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ak1 adenylate kinase 1 decreases expression ISO cobalt sulfate results in decreased expression of AK1 mRNA CTD PMID:19502547 NCBI chr 2:32,511,770...32,525,070
Ensembl chr 2:32,511,770...32,525,070 		JBrowse link
G Ankrd37 ankyrin repeat domain 37 increases expression ISO cobalt sulfate results in increased expression of ANKRD37 mRNA CTD PMID:19502547 NCBI chr 8:46,449,945...46,452,904
Ensembl chr 8:46,449,939...46,458,744 		JBrowse link
G Bax BCL2-associated X protein decreases expression ISO cobalt sulfate results in decreased expression of BAX protein CTD PMID:25310813 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322 		JBrowse link
G Car9 carbonic anhydrase 9 increases expression ISO cobalt sulfate results in increased expression of CA9 mRNA CTD PMID:19502547 NCBI chr 4:43,507,026...43,513,729
Ensembl chr 4:43,506,966...43,513,729 		JBrowse link
G Casp3 caspase 3 decreases expression ISO cobalt sulfate results in decreased expression of CASP3 protein CTD PMID:25310813 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 increases secretion
increases expression		 ISO cobalt sulfate results in increased secretion of CCL4 protein
cobalt sulfate results in increased expression of CCL4 mRNA		 CTD PMID:16314067 PMID:20713136 NCBI chr11:83,553,410...83,555,509
Ensembl chr11:83,553,410...83,555,509 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 increases expression ISO cobalt sulfate results in increased expression of CXCL1 mRNA CTD PMID:20713136 NCBI chr 5:91,039,104...91,040,980
Ensembl chr 5:91,039,100...91,040,974 		JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 increases expression ISO cobalt sulfate results in increased expression of CXCL8 mRNA CTD PMID:20713136 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 increases expression ISO cobalt sulfate results in increased expression of CXCL1 mRNA CTD PMID:20713136 NCBI chr 5:90,933,960...90,935,952
Ensembl chr 5:90,933,962...90,937,459 		JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 increases expression ISO cobalt sulfate results in increased expression of EGLN1 mRNA CTD PMID:19502547 NCBI chr 8:125,635,325...125,676,063
Ensembl chr 8:125,635,326...125,676,063 		JBrowse link
G Egln2 egl-9 family hypoxia-inducible factor 2 decreases expression ISO cobalt sulfate results in decreased expression of EGLN2 mRNA CTD PMID:19502547 NCBI chr 7:26,858,083...26,866,227
Ensembl chr 7:26,858,083...26,866,227 		JBrowse link
G Eno1 enolase 1, alpha non-neuron increases expression ISO cobalt sulfate results in increased expression of ENO1 mRNA CTD PMID:19502547 NCBI chr 4:150,321,165...150,333,336
Ensembl chr 4:150,321,178...150,333,336 		JBrowse link
G Eno2 enolase 2, gamma neuronal increases expression ISO cobalt sulfate results in increased expression of ENO2 mRNA CTD PMID:19502547 NCBI chr 6:124,737,018...124,746,489
Ensembl chr 6:124,737,016...124,746,636 		JBrowse link
G Fos FBJ osteosarcoma oncogene increases expression ISO cobalt sulfate results in increased expression of FOS mRNA CTD PMID:10362023 NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047 		JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase increases expression ISO cobalt sulfate results in increased expression of GAPDH mRNA CTD PMID:19502547 NCBI chr 6:125,138,812...125,143,450
Ensembl chr 6:125,138,678...125,143,430 		JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit multiple interactions
increases activity		 EXP
ISO		 HIF1A protein promotes the reaction [cobalt sulfate results in increased expression of VEGFA protein]
cobalt sulfate results in increased activity of HIF1A protein		 CTD PMID:19502547 NCBI chr12:73,948,186...73,994,304
Ensembl chr12:73,948,149...73,994,304 		JBrowse link
G Hif3a hypoxia inducible factor 3, alpha subunit decreases expression ISO cobalt sulfate results in decreased expression of HIF3A mRNA CTD PMID:19502547 NCBI chr 7:16,764,918...16,796,352
Ensembl chr 7:16,765,432...16,796,352 		JBrowse link
G Hilpda hypoxia inducible lipid droplet associated increases expression ISO cobalt sulfate results in increased expression of HILPDA mRNA CTD PMID:19502547 NCBI chr 6:29,272,487...29,275,448
Ensembl chr 6:29,272,487...29,275,445 		JBrowse link
G Hk2 hexokinase 2 increases expression ISO cobalt sulfate results in increased expression of HK2 mRNA CTD PMID:19502547 NCBI chr 6:82,702,004...82,751,437
Ensembl chr 6:82,702,006...82,751,435 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO cobalt sulfate results in increased expression of HMOX1 mRNA CTD PMID:20713136 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217 		JBrowse link
G Igf1 insulin-like growth factor 1 increases secretion ISO cobalt sulfate results in increased secretion of IGF1 protein CTD PMID:25310813 NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904 		JBrowse link
G Il1b interleukin 1 beta increases expression ISO cobalt sulfate results in increased expression of IL1B mRNA CTD PMID:20713136 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059 		JBrowse link
G Il7r interleukin 7 receptor increases expression ISO cobalt sulfate results in increased expression of IL7R mRNA CTD PMID:20713136 NCBI chr15:9,505,880...9,530,270
Ensembl chr15:9,505,874...9,530,262 		JBrowse link
G Ldha lactate dehydrogenase A increases expression ISO cobalt sulfate results in increased expression of LDHA mRNA CTD PMID:19502547 NCBI chr 7:46,491,698...46,505,051
Ensembl chr 7:46,490,899...46,505,051 		JBrowse link
G Mif macrophage migration inhibitory factor (glycosylation-inhibiting factor) increases expression ISO cobalt sulfate results in increased expression of MIF mRNA CTD PMID:19502547 NCBI chr10:75,695,187...75,696,111
Ensembl chr10:75,695,187...75,696,074 		JBrowse link
G Mt2 metallothionein 2 increases expression ISO cobalt sulfate results in increased expression of MT2A mRNA CTD PMID:10362023 NCBI chr 8:94,899,246...94,900,195
Ensembl chr 8:94,899,292...94,900,196 		JBrowse link
G Nppb natriuretic peptide type B increases expression ISO cobalt sulfate results in increased expression of NPPB mRNA CTD PMID:19502547 NCBI chr 4:148,070,264...148,071,662
Ensembl chr 4:148,070,245...148,071,662 		JBrowse link
G Pdk1 pyruvate dehydrogenase kinase, isoenzyme 1 increases expression ISO cobalt sulfate results in increased expression of PDK1 mRNA CTD PMID:19502547 NCBI chr 2:71,703,398...71,734,202
Ensembl chr 2:71,703,568...71,734,202 		JBrowse link
G Pgk1 phosphoglycerate kinase 1 increases expression ISO cobalt sulfate results in increased expression of PGK1 mRNA CTD PMID:19502547 NCBI chr  X:105,230,706...105,247,305
Ensembl chr  X:105,230,706...105,247,305 		JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression ISO cobalt sulfate results in increased expression of PMAIP1 mRNA CTD PMID:20713136 NCBI chr18:66,591,675...66,598,629
Ensembl chr18:66,591,604...66,598,636 		JBrowse link
G Ppp2r1b protein phosphatase 2, regulatory subunit A, beta decreases expression ISO cobalt sulfate results in decreased expression of PPP2R1B mRNA CTD PMID:19502547 NCBI chr 9:50,767,946...50,810,625
Ensembl chr 9:50,756,601...50,805,529 		JBrowse link
G Tfrc transferrin receptor increases expression ISO cobalt sulfate results in increased expression of TFRC mRNA CTD PMID:19502547 NCBI chr16:32,427,714...32,451,612
Ensembl chr16:32,427,738...32,451,612 		JBrowse link
G Tnfaip3 tumor necrosis factor, alpha-induced protein 3 increases expression ISO cobalt sulfate results in increased expression of TNFAIP3 mRNA CTD PMID:20713136 NCBI chr10:18,876,658...18,891,158
Ensembl chr10:18,876,658...18,891,405 		JBrowse link
G Tnfaip6 tumor necrosis factor alpha induced protein 6 increases expression ISO cobalt sulfate results in increased expression of TNFAIP6 mRNA CTD PMID:20713136 NCBI chr 2:51,928,125...51,946,693
Ensembl chr 2:51,928,021...51,946,698 		JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression
increases expression
multiple interactions		 ISO
EXP		 cobalt sulfate results in decreased expression of VEGFA mRNA
cobalt sulfate results in increased expression of VEGFA protein
HIF1A protein promotes the reaction [cobalt sulfate results in increased expression of VEGFA protein]		 CTD PMID:19502547 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22178
    role 22194
      biological role 22162
        biochemical role 21431
          cofactor 16825
            cobalt(2+) 4267
              cobalt(2+) sulfate 35
                cobalt(2+) sulfate heptahydrate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 22178
    subatomic particle 22170
      composite particle 22170
        hadron 22201
          baryon 22170
            nucleon 22170
              atomic nucleus 22170
                atom 22170
                  main group element atom 22104
                    p-block element atom 22104
                      chalcogen 21431
                        oxygen atom 21437
                          oxygen molecular entity 21409
                            hydroxides 20789
                              oxoacid 20101
                                chalcogen oxoacid 14366
                                  sulfur oxoacid 14151
                                    sulfuric acid 8516
                                      sulfuric acid derivative 8516
                                        sulfates 8511
                                          sulfate salt 7159
                                            inorganic sulfate salt 7103
                                              metal sulfate 7094
                                                cobalt(2+) sulfate 35
                                                  cobalt(2+) sulfate heptahydrate 0
paths to the root