CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: ethylene glycol dimethacrylate
Accession: CHEBI:53436
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Definition: The enoate ester that is the 1,2-bis(methacryloyl) derivative of ethylene glycol.
Synonyms: exact_synonym: ethane-1,2-diyl bis(2-methylacrylate)
related_synonym: 1,2-Bis(methacryloyloxy)ethane; 1,2-Ethanediol dimethacrylate; 1,2-Ethanediyl 2-methyl-2-propenoate; 2-(Methacryloyloxy)ethyl 2-methylacrylate; 2-methyl-2-propenoic acid 1,2-ethanediyl ester; Diglycol dimethacrylate; EGDMA; Ethanediol dimethacrylate; Ethyldiol metacrylate; Ethyldiol methacrylate; Ethylene dimethacrylate; Ethylene glycol bis(methacrylate); Ethylene methacrylate; Ethylenedimethyacrylate; Formula=C10H14O4; Glycol dimethacrylate; InChI=1S/C10H14O4/c1-7(2)9(11)13-5-6-14-10(12)8(3)4/h1,3,5-6H2,2,4H3; InChIKey=STVZJERGLQHEKB-UHFFFAOYSA-N; Methacrylic acid ethylene ester; SMILES=CC(=C)C(=O)OCCOC(=O)C(C)=C
xref: CAS:97-90-5; Gmelin:637376
xref_mesh: MESH:C004919
xref: PMID:10444249; PMID:11714252; PMID:19091218; PMID:23161346; PMID:23180752; PMID:23229725; PMID:23246931; PMID:23350065; PMID:23351340; PMID:23360228; PMID:23390113; PMID:23465129; PMID:23481473; PMID:23544352; PMID:23560989; PMID:23561202; PMID:23602644; PMID:23640909; PMID:23726080; PMID:23780342; Reaxys:1776663; Wikipedia:Ethylene_glycol_dimethacrylate
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Akr1c2
aldo-keto reductase family 1, member C2
increases activity
ISO
ethylene dimethacrylate results in increased activity of AKR1C2 promoter
CTD
PMID:21195160
NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
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Atf3
activating transcription factor 3
increases expression
ISO
ethylene dimethacrylate results in increased expression of ATF3 mRNA
CTD
PMID:27965148
NCBI chr13:105,274,103...105,331,653
Ensembl chr13:102,751,321...102,764,631
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Bach1
BTB domain and CNC homolog 1
multiple interactions
ISO
BACH1 mRNA promotes the reaction [ethylene dimethacrylate results in increased expression of HMOX1 mRNA]
CTD
PMID:26244607
NCBI chr11:26,939,429...26,974,876
Ensembl chr11:26,939,480...26,972,447
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Cd86
CD86 molecule
increases expression
ISO
ethylene dimethacrylate results in increased expression of CD86 protein
CTD
PMID:19665512
NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
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Cxcl14
C-X-C motif chemokine ligand 14
decreases expression
ISO
ethylene dimethacrylate results in decreased expression of CXCL14 protein
CTD
PMID:31734321
NCBI chr17:8,317,930...8,325,956
Ensembl chr17:8,317,933...8,324,839
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Cxcl2
C-X-C motif chemokine ligand 2
increases expression
ISO
ethylene dimethacrylate results in increased expression of CXCL2 protein
CTD
PMID:23178550
NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
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Gclm
glutamate cysteine ligase, modifier subunit
increases expression
ISO
ethylene dimethacrylate results in increased expression of GCLM mRNA
CTD
PMID:27965148
NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:210,347,482...210,367,535
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Gpx4
glutathione peroxidase 4
increases expression
ISO
ethylene dimethacrylate results in increased expression of GPX4
CTD
PMID:29107684
NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
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Hmox1
heme oxygenase 1
increases expression multiple interactions
ISO
ethylene dimethacrylate results in increased expression of HMOX1 mRNA BACH1 mRNA promotes the reaction [ethylene dimethacrylate results in increased expression of HMOX1 mRNA]; NFE2L2 mRNA promotes the reaction [ethylene dimethacrylate results in increased expression of HMOX1 mRNA]
CTD
PMID:26244607
NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079
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Il1a
interleukin 1 alpha
increases expression
ISO
ethylene dimethacrylate results in increased expression of IL1A protein
CTD
PMID:23178550
NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
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Nfe2l2
NFE2 like bZIP transcription factor 2
multiple interactions
ISO
NFE2L2 mRNA promotes the reaction [ethylene dimethacrylate results in increased expression of HMOX1 mRNA]
CTD
PMID:26244607
NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737
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Sod2
superoxide dismutase 2
increases expression
ISO
ethylene dimethacrylate results in increased expression of SOD2
CTD
PMID:29107684
NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:47,636,528...47,645,189
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