1,4-bis(2-ethylhexyl) sulfosuccinate - Ontology Report - Rat Genome Database

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CHEBI ONTOLOGY - ANNOTATIONS

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	1,4-bis(2-ethylhexyl) sulfosuccinate	go back to main search page
Accession:	CHEBI:534	browse the term
Definition:	A succinate ester that has formula C20H38O7S.
Synonyms:	related_synonym:	1,4-bis(2-ethylhexoxy)-1,4-bis(oxidanylidene)butane-2-sulfonic acid; 1,4-bis(2-ethylhexoxy)-1,4-diketo-butane-2-sulfonic acid; 1,4-bis(2-ethylhexoxy)-1,4-dioxo-2-butanesulfonic acid; 1,4-bis(2-ethylhexoxy)-1,4-dioxo-butane-2-sulfonic acid; 1,4-bis(2-ethylhexoxy)-1,4-dioxobutane-2-sulfonic acid; 1,4-bis[(2-ethylhexyl)oxy]-1,4-dioxobutane-2-sulfonic acid; 1-(2-Methylphenyl)ethanone; 1-(2-Tolyl)ethanone; 1-(Methylphenyl)-Ethanone; 1-(Methylphenyl)ethan-1-one; 2'-Methyl-Acetophenone; 2'-Methylacetophenone; 2'-Methylacetylphenone; 2-Acetyltoluene; Acetophenone, 2'-methyl- (8CI); Docusate hydrogen; Ethanone, 1-(2-methylphenyl)- (9CI); Formula=C20H38O7S; InChI=1S/C20H38O7S/c1-5-9-11-16(7-3)14-26-19(21)13-18(28(23,24)25)20(22)27-15-17(8-4)12-10-6-2/h16-18H,5-15H2,1-4H3,(H,23,24,25); InChIKey=HNSDLXPSAYFUHK-UHFFFAOYSA-N; Methyl O-tolyl ketone; O-Acetyltoluene; O-Methyl acetophenone; O-Methylacetophenone; SMILES=CCCCC(CC)COC(=O)CC(C(=O)OCC(CC)CCCC)S(O)(=O)=O; dioctyl disodium sulfosuccinate; dioctyl sulfosuccinate; dioctyl sulfosuccinic acid; docusate; docusate calcium
	xref:	CAS:10041-19-7; CAS:577-16-2; Drug_Central:941; HMDB:HMDB0032386; KEGG:C07874
	xref_mesh:	MESH:D004143
	xref:	PMID:19167006

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Genes (5)

1,4-bis(2-ethylhexyl) sulfosuccinate

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

delta like non-canonical Notch ligand 1

decreases expression

Dioctyl Sulfosuccinic Acid results in decreased expression of DLK1 mRNA

NCBI chr 6:133,576,513...133,583,751
Ensembl chr 6:133,552,821...133,583,751

G

fatty acid binding protein 4

increases expression

Dioctyl Sulfosuccinic Acid results in increased expression of FABP4 mRNA

NCBI chr 2:93,792,666...93,797,267
Ensembl chr 2:93,792,601...93,797,305

G

peroxisome proliferator activated receptor alpha

increases activity

Dioctyl Sulfosuccinic Acid results in increased activity of PPARA protein

NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752

G

peroxisome proliferator-activated receptor delta

increases activity

Dioctyl Sulfosuccinic Acid results in increased activity of PPARD protein

NCBI chr20:7,818,289...7,883,482
Ensembl chr20:7,818,289...7,885,333

G

peroxisome proliferator-activated receptor gamma

multiple interactions
increases activity

Dioctyl Sulfosuccinic Acid binds to and results in increased activity of PPARG protein
Dioctyl Sulfosuccinic Acid results in increased activity of PPARG protein

NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	19817
chemical entity	19817
group	19728
inorganic group	19174
sulfo group	5752
organosulfonic acid	5752
1,4-bis(2-ethylhexyl) sulfosuccinate	5
Path 2
Term	Annotations
CHEBI ontology	19817
subatomic particle	19815
composite particle	19815
hadron	19815
baryon	19815
nucleon	19815
atomic nucleus	19815
atom	19815
main group element atom	19705
p-block element atom	19705
chalcogen	19407
oxygen atom	19368
oxygen molecular entity	19368
hydroxides	19094
oxoacid	18243
chalcogen oxoacid	11496
sulfur oxoacid	11102
sulfonic acid	7356
sulfo group	5752
organosulfonic acid	5752
1,4-bis(2-ethylhexyl) sulfosuccinate	5

paths to the root