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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:GHB receptor agonist
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Accession:CHEBI:53353 term browser browse the term
Definition:A drug that binds to and activates gamma-hydroxybutyric acid receptors.
Synonyms:related_synonym: GHB receptor agonists


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4-hydroxybutyric acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh5a1 aldehyde dehydrogenase 5 family, member A1 increases abundance ISO ALDH5A1 mutant form results in increased abundance of 4-hydroxybutyric acid
ALDH5A1 gene mutant form results in increased abundance of 4-hydroxybutyric acid
CTD PMID:17438226, PMID:29031482 NCBI chr17:42,133,076...42,159,413
Ensembl chr17:42,133,076...42,159,413
JBrowse link
G Gh1 growth hormone 1 multiple interactions
increases secretion
ISO Cocaine inhibits the reaction [4-hydroxybutyric acid results in increased secretion of GH1 protein] CTD PMID:10657535 NCBI chr10:94,486,204...94,488,181
Ensembl chr10:94,486,205...94,488,180
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19770
    role 19718
      biological role 19717
        pharmacological role 18795
          neurotransmitter agent 16422
            GHB receptor agonist 2
              4-hydroxybutyric acid + 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19770
    role 19718
      application 19363
        pharmaceutical 19235
          drug 19235
            neurotransmitter agent 16422
              GHB receptor agonist 2
                4-hydroxybutyric acid + 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.