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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:GHB receptor agonist
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Accession:CHEBI:53353 term browser browse the term
Definition:A drug that binds to and activates gamma-hydroxybutyric acid receptors.
Synonyms:related_synonym: GHB receptor agonists


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4-hydroxybutyric acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh5a1 aldehyde dehydrogenase 5 family, member A1 increases abundance ISO ALDH5A1 mutant form results in increased abundance of 4-hydroxybutyric acid
ALDH5A1 gene mutant form results in increased abundance of 4-hydroxybutyric acid		 CTD PMID:17438226 PMID:29031482 NCBI chr17:40,132,339...40,158,677
Ensembl chr17:40,130,883...40,158,677 		JBrowse link
G Gh1 growth hormone 1 multiple interactions
increases secretion		 ISO Cocaine inhibits the reaction [4-hydroxybutyric acid results in increased secretion of GH1 protein] CTD PMID:10657535 NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19811
    role 19818
      biological role 19785
        pharmacological role 19030
          neurotransmitter agent 16721
            GHB receptor agonist 2
              4-hydroxybutyric acid + 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19811
    role 19818
      application 19630
        pharmaceutical 19503
          drug 19471
            neurotransmitter agent 16721
              GHB receptor agonist 2
                4-hydroxybutyric acid + 2
paths to the root