|
G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions |
ISO EXP |
tetraiodothyroacetic acid inhibits the reaction [Thyroxine results in increased phosphorylation of and results in increased activity of MAPK1 protein]; tetraiodothyroacetic acid inhibits the reaction [Triiodothyronine results in increased phosphorylation of and results in increased activity of MAPK1 protein] tetraiodothyroacetic acid inhibits the reaction [Thyroxine affects the localization of MAPK1 protein] |
CTD |
PMID:17174366 PMID:17984113 |
|
NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
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|
G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions |
ISO EXP |
tetraiodothyroacetic acid inhibits the reaction [Thyroxine results in increased phosphorylation of and results in increased activity of MAPK3 protein]; tetraiodothyroacetic acid inhibits the reaction [Triiodothyronine results in increased phosphorylation of and results in increased activity of MAPK3 protein] tetraiodothyroacetic acid inhibits the reaction [Thyroxine affects the localization of MAPK3 protein] |
CTD |
PMID:17174366 PMID:17984113 |
|
NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
|
|
G |
Ncoa2 |
nuclear receptor coactivator 2 |
multiple interactions |
ISO |
tetraiodothyroacetic acid promotes the reaction [THRA protein binds to NCOA2 protein]; tetraiodothyroacetic acid promotes the reaction [THRB protein binds to NCOA2 protein] |
CTD |
PMID:31566444 |
|
NCBI chr 5:5,466,544...5,696,540
Ensembl chr 5:5,616,483...5,694,598
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|
G |
Ncor1 |
nuclear receptor co-repressor 1 |
multiple interactions |
ISO |
tetraiodothyroacetic acid inhibits the reaction [Thyroxine inhibits the reaction [THRB protein binds to NCOR1 protein]]; tetraiodothyroacetic acid inhibits the reaction [Triiodothyronine inhibits the reaction [THRB protein binds to NCOR1 protein]] |
CTD |
PMID:22227104 |
|
NCBI chr10:48,629,121...48,772,890
Ensembl chr10:48,629,121...48,772,890
|
|
G |
Ncor2 |
nuclear receptor co-repressor 2 |
multiple interactions |
ISO |
tetraiodothyroacetic acid inhibits the reaction [Thyroxine inhibits the reaction [THRB protein binds to NCOR2 protein]]; tetraiodothyroacetic acid inhibits the reaction [Triiodothyronine inhibits the reaction [THRB protein binds to NCOR2 protein]] |
CTD |
PMID:22227104 |
|
NCBI chr12:36,871,917...37,033,701
Ensembl chr12:36,871,999...37,033,701
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|
G |
Rxra |
retinoid X receptor alpha |
affects binding |
ISO |
tetraiodothyroacetic acid binds to RXRA protein |
CTD |
PMID:31566444 |
|
NCBI chr 3:6,272,560...6,295,354
Ensembl chr 3:6,211,789...6,295,908
|
|
G |
Thra |
thyroid hormone receptor alpha |
multiple interactions |
ISO |
tetraiodothyroacetic acid promotes the reaction [THRA protein binds to NCOA2 protein] |
CTD |
PMID:31566444 |
|
NCBI chr10:86,657,285...86,684,935
Ensembl chr10:86,657,285...86,684,933
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|
G |
Thrb |
thyroid hormone receptor beta |
multiple interactions affects binding increases activity |
ISO |
tetraiodothyroacetic acid inhibits the reaction [Thyroxine inhibits the reaction [THRB protein binds to NCOR1 protein]]; tetraiodothyroacetic acid inhibits the reaction [Thyroxine inhibits the reaction [THRB protein binds to NCOR2 protein]]; tetraiodothyroacetic acid inhibits the reaction [Triiodothyronine inhibits the reaction [THRB protein binds to NCOR1 protein]]; tetraiodothyroacetic acid inhibits the reaction [Triiodothyronine inhibits the reaction [THRB protein binds to NCOR2 protein]]; tetraiodothyroacetic acid promotes the reaction [THRB protein binds to NCOA2 protein] tetraiodothyroacetic acid binds to THRB protein tetraiodothyroacetic acid results in increased activity of THRB protein |
CTD |
PMID:22227104 PMID:31077750 PMID:31566444 |
|
NCBI chr15:8,890,578...9,239,815
Ensembl chr15:8,890,578...9,086,282
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|
G |
Tp53 |
tumor protein p53 |
multiple interactions |
EXP |
tetraiodothyroacetic acid inhibits the reaction [Thyroxine affects the localization of TP53 protein modified form] |
CTD |
PMID:17984113 |
|
NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
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|
|
G |
Abca1 |
ATP binding cassette subfamily A member 1 |
increases expression |
ISO |
Triiodothyronine results in increased expression of ABCA1 mRNA |
CTD |
PMID:25172293 |
|
NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015
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|
G |
Abcb11 |
ATP binding cassette subfamily B member 11 |
decreases activity |
ISO |
Triiodothyronine results in decreased activity of ABCB11 protein |
CTD |
PMID:28437613 |
|
NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
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|
G |
Abcb4 |
ATP binding cassette subfamily B member 4 |
decreases activity |
ISO |
Triiodothyronine results in decreased activity of ABCB4 protein |
CTD |
PMID:28437613 |
|
NCBI chr 4:22,133,984...22,192,687
Ensembl chr 4:22,133,521...22,425,515
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G |
Abcc5 |
ATP binding cassette subfamily C member 5 |
increases expression |
EXP |
Triiodothyronine results in increased expression of ABCC5 mRNA |
CTD |
PMID:29357290 |
|
NCBI chr11:84,395,982...84,490,215
Ensembl chr11:84,396,033...84,490,211
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|
G |
Abcf3 |
ATP binding cassette subfamily F member 3 |
multiple interactions |
ISO |
[Triiodothyronine co-treated with Tetrachlorodibenzodioxin] results in decreased expression of ABCF3 mRNA |
CTD |
PMID:14761676 |
|
NCBI chr11:84,026,206...84,037,938
Ensembl chr11:84,026,207...84,037,938
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|
G |
Acaca |
acetyl-CoA carboxylase alpha |
multiple interactions increases expression increases activity |
EXP |
Triiodothyronine inhibits the reaction [Streptozocin results in decreased activity of ACACA protein]; Triiodothyronine inhibits the reaction [Streptozocin results in decreased expression of ACACA mRNA] Triiodothyronine results in increased expression of ACACA mRNA Triiodothyronine results in increased activity of ACACA protein |
CTD |
PMID:1973097 |
|
NCBI chr10:71,519,392...71,719,910
Ensembl chr10:71,536,533...71,719,910
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G |
Acbd4 |
acyl-CoA binding domain containing 4 |
decreases expression |
ISO |
Triiodothyronine results in decreased expression of ACBD4 mRNA |
CTD |
PMID:23397585 |
|
NCBI chr10:91,186,131...91,200,081
Ensembl chr10:91,187,593...91,196,572
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G |
Ace |
angiotensin I converting enzyme |
multiple interactions |
EXP |
Triiodothyronine results in increased expression of and results in increased activity of ACE protein |
CTD |
PMID:1659346 |
|
NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
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G |
Acot1 |
acyl-CoA thioesterase 1 |
increases expression decreases expression |
EXP |
Triiodothyronine results in increased expression of ACOT1 mRNA Triiodothyronine results in decreased expression of ACOT1 mRNA |
CTD |
PMID:15953391 PMID:28299817 |
|
NCBI chr 6:107,485,088...107,493,082
Ensembl chr 6:107,485,249...107,493,798
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G |
Acsl1 |
acyl-CoA synthetase long-chain family member 1 |
increases expression |
ISO |
Triiodothyronine results in increased expression of ACSL1 mRNA |
CTD |
PMID:30209975 |
|
NCBI chr16:48,937,456...49,003,898
Ensembl chr16:48,937,456...49,003,246
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G |
Acsl5 |
acyl-CoA synthetase long-chain family member 5 |
increases expression |
EXP |
Triiodothyronine results in increased expression of ACSL5 mRNA |
CTD |
PMID:15953391 |
|
NCBI chr 1:276,240,703...276,290,012
Ensembl chr 1:276,240,703...276,290,008
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G |
Acvrl1 |
activin A receptor like type 1 |
increases expression |
ISO |
Triiodothyronine results in increased expression of ACVRL1 mRNA |
CTD |
PMID:25172293 |
|
NCBI chr 7:142,769,942...142,787,336
Ensembl chr 7:142,776,252...142,787,335
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G |
Adam11 |
ADAM metallopeptidase domain 11 |
increases expression |
ISO |
Triiodothyronine results in increased expression of ADAM11 mRNA |
CTD |
PMID:25172293 |
|
NCBI chr10:90,731,260...90,749,221
Ensembl chr10:90,731,148...90,749,217
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G |
Adam12 |
ADAM metallopeptidase domain 12 |
increases expression |
ISO |
Triiodothyronine results in increased expression of ADAM12 mRNA |
CTD |
PMID:23397585 |
|
NCBI chr 1:205,951,840...206,286,294
Ensembl chr 1:205,956,342...206,282,575
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G |
Adam15 |
ADAM metallopeptidase domain 15 |
decreases expression |
ISO |
Triiodothyronine results in decreased expression of ADAM15 mRNA |
CTD |
PMID:23397585 |
|
NCBI chr 2:188,661,831...188,672,337
Ensembl chr 2:188,661,699...188,672,247
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|
G |
Adam19 |
ADAM metallopeptidase domain 19 |
multiple interactions |
ISO |
[Triiodothyronine co-treated with Tetrachlorodibenzodioxin] results in decreased expression of ADAM19 mRNA |
CTD |
PMID:14761676 |
|
NCBI chr10:31,146,107...31,240,582
Ensembl chr10:31,146,107...31,240,582
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G |
Add2 |
adducin 2 |
increases expression |
ISO |
Triiodothyronine results in increased expression of ADD2 mRNA |
CTD |
PMID:23397585 |
|
NCBI chr 4:117,691,294...117,887,556
Ensembl chr 4:117,743,710...117,882,464
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G |
Adrb1 |
adrenoceptor beta 1 |
increases expression |
EXP |
Triiodothyronine results in increased expression of ADRB1 mRNA; Triiodothyronine results in increased expression of ADRB1 protein |
CTD |
PMID:10217540 PMID:11090638 |
|
NCBI chr 1:277,537,585...277,538,985
Ensembl chr 1:277,537,585...277,538,985
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G |
Adrb2 |
adrenoceptor beta 2 |
multiple interactions increases expression |
ISO |
bicalutamide inhibits the reaction [Triiodothyronine results in increased expression of ADRB2 protein] Triiodothyronine results in increased expression of ADRB2 mRNA; Triiodothyronine results in increased expression of ADRB2 protein |
CTD |
PMID:18454446 |
|
NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834
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|
G |
Adrb3 |
adrenoceptor beta 3 |
multiple interactions increases expression decreases expression |
EXP |
Amiodarone inhibits the reaction [Triiodothyronine results in decreased expression of ADRB3 protein] Triiodothyronine results in increased expression of ADRB3 protein Triiodothyronine results in decreased expression of ADRB3 mRNA; Triiodothyronine results in decreased expression of ADRB3 protein |
CTD |
PMID:8836703 PMID:10217540 |
|
NCBI chr16:69,003,541...69,006,632
Ensembl chr16:69,003,868...69,006,632
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G |
Ahr |
aryl hydrocarbon receptor |
multiple interactions |
ISO |
Triiodothyronine promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of AHR mRNA] |
CTD |
PMID:28478156 |
|
NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
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G |
Akap12 |
A-kinase anchoring protein 12 |
increases expression |
ISO |
Triiodothyronine results in increased expression of AKAP12 mRNA |
CTD |
PMID:23397585 |
|
NCBI chr 1:40,816,130...40,906,582
Ensembl chr 1:40,816,107...40,906,581
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G |
Akirin2 |
akirin 2 |
increases expression |
ISO |
Triiodothyronine results in increased expression of AKIRIN2 mRNA |
CTD |
PMID:23397585 |
|
NCBI chr 5:50,001,945...50,016,544
Ensembl chr 5:50,002,184...50,016,539
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G |
Akr1c2 |
aldo-keto reductase family 1, member C2 |
increases expression |
ISO |
Triiodothyronine results in increased expression of AKR1C2 mRNA |
CTD |
PMID:15507505 |
|
NCBI chr17:69,388,337...69,435,160
Ensembl chr17:69,388,335...69,404,341
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G |
Akr1c3 |
aldo-keto reductase family 1, member C3 |
increases expression |
ISO |
Triiodothyronine results in increased expression of AKR1C3 mRNA |
CTD |
PMID:15507505 |
|
NCBI chr17:69,761,126...69,778,021
Ensembl chr17:69,761,118...69,778,021
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G |
Akt1 |
AKT serine/threonine kinase 1 |
multiple interactions increases phosphorylation |
EXP ISO |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Triiodothyronine results in increased phosphorylation of AKT1 protein]; AKT1 protein affects the reaction [Triiodothyronine affects the expression of TTN mRNA] |
CTD |
PMID:16021636 PMID:18096819 |
|
NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
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G |
Alb |
albumin |
affects binding |
ISO |
Triiodothyronine binds to ALB protein |
CTD |
PMID:21517007 |
|
NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
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G |
Aldh1a3 |
aldehyde dehydrogenase 1 family, member A3 |
multiple interactions |
ISO |
[Triiodothyronine co-treated with Tetrachlorodibenzodioxin] results in increased expression of ALDH1A3 mRNA |
CTD |
PMID:14761676 |
|
NCBI chr 1:127,302,920...127,337,828
Ensembl chr 1:127,301,128...127,337,882
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G |
Aldh3a2 |
aldehyde dehydrogenase 3 family, member A2 |
increases expression |
EXP |
Triiodothyronine results in increased expression of ALDH3A2 mRNA |
CTD |
PMID:15953391 |
|
NCBI chr10:47,525,486...47,546,535
Ensembl chr10:47,525,493...47,546,345
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G |
Amh |
anti-Mullerian hormone |
multiple interactions |
EXP |
Triiodothyronine affects the reaction [Propylthiouracil affects the expression of AMH mRNA] |
CTD |
PMID:7819453 |
|
NCBI chr 7:11,775,155...11,777,503
Ensembl chr 7:11,775,155...11,777,503
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G |
Angptl8 |
angiopoietin-like 8 |
multiple interactions |
ISO |
[THRA protein co-treated with Triiodothyronine] promotes the reaction [ANGPTL8 protein binds to PLIN3 protein]; [THRA protein co-treated with Triiodothyronine] results in increased expression of ANGPTL8 mRNA; [THRA protein co-treated with Triiodothyronine] results in increased expression of ANGPTL8 protein; [THRB protein co-treated with Triiodothyronine] results in increased expression of ANGPTL8 mRNA; ANGPTL8 protein affects the reaction [[THRA protein co-treated with Triiodothyronine] results in decreased expression of SQSTM1 protein] |
CTD |
PMID:24262987 |
|
NCBI chr 8:22,855,495...22,858,565
Ensembl chr 8:22,856,539...22,858,565
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G |
Apoa1 |
apolipoprotein A1 |
increases expression |
EXP |
Triiodothyronine results in increased expression of APOA1 protein |
CTD |
PMID:6816881 |
|
NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
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G |
Apoa4 |
apolipoprotein A4 |
multiple interactions |
EXP |
Triiodothyronine results in increased expression of [APOE protein co-treated with APOA4 protein] |
CTD |
PMID:6816881 |
|
NCBI chr 8:50,536,983...50,539,371
Ensembl chr 8:50,537,009...50,539,376
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G |
Apoe |
apolipoprotein E |
multiple interactions |
EXP |
Triiodothyronine results in increased expression of [APOE protein co-treated with APOA4 protein] |
CTD |
PMID:6816881 |
|
NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
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G |
App |
amyloid beta precursor protein |
decreases expression multiple interactions |
ISO |
Triiodothyronine results in decreased expression of APP mRNA; Triiodothyronine results in decreased expression of APP protein Tretinoin promotes the reaction [Triiodothyronine results in decreased secretion of APP protein] |
CTD |
PMID:17199430 |
|
NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
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G |
Aqp1 |
aquaporin 1 |
increases expression |
ISO |
Triiodothyronine results in increased expression of AQP1 mRNA |
CTD |
PMID:25172293 |
|
NCBI chr 4:85,551,503...85,563,683
Ensembl chr 4:85,551,502...85,569,360
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G |
Aqp8 |
aquaporin 8 |
increases expression |
EXP |
Triiodothyronine results in increased expression of AQP8 mRNA |
CTD |
PMID:15953391 |
|
NCBI chr 1:193,424,818...193,430,665
Ensembl chr 1:193,424,812...193,430,676
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|
G |
Arhgef25 |
Rho guanine nucleotide exchange factor 25 |
decreases expression |
ISO |
Triiodothyronine results in decreased expression of ARHGEF25 mRNA |
CTD |
PMID:23397585 |
|
NCBI chr 7:70,469,304...70,476,633
Ensembl chr 7:70,469,312...70,476,340
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|
G |
Arl4d |
ADP-ribosylation factor like GTPase 4D |
increases expression |
ISO |
Triiodothyronine results in increased expression of ARL4D mRNA |
CTD |
PMID:25172293 |
|
NCBI chr10:89,577,556...89,580,368
Ensembl chr10:89,578,212...89,580,368
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|
G |
Arrdc3 |
arrestin domain containing 3 |
increases expression |
EXP |
Triiodothyronine results in increased expression of ARRDC3 mRNA |
CTD |
PMID:28299817 |
|
NCBI chr 2:8,732,907...8,745,445
Ensembl chr 2:8,732,932...8,743,069
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G |
Aspg |
asparaginase |
increases expression |
EXP |
Triiodothyronine results in increased expression of ASPG mRNA |
CTD |
PMID:29357290 |
|
NCBI chr 6:136,682,279...136,701,673
Ensembl chr 6:136,682,126...136,701,628
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G |
Aspm |
assembly factor for spindle microtubules |
decreases expression |
ISO |
Triiodothyronine results in decreased expression of ASPM mRNA |
CTD |
PMID:23397585 |
|
NCBI chr13:56,546,021...56,591,793
Ensembl chr13:56,546,021...56,591,793
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G |
Atg5 |
autophagy related 5 |
increases expression affects response to substance |
ISO |
Triiodothyronine results in increased expression of ATG5 mRNA; Triiodothyronine results in increased expression of ATG5 protein ATG5 protein affects the susceptibility to Triiodothyronine |
CTD |
PMID:30209975 |
|
NCBI chr20:49,301,783...49,393,147
Ensembl chr20:49,318,308...49,393,140
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G |
Atg7 |
autophagy related 7 |
increases expression |
ISO |
Triiodothyronine results in increased expression of ATG7 mRNA |
CTD |
PMID:30209975 |
|
NCBI chr 4:146,570,113...146,777,093
Ensembl chr 4:146,598,413...146,777,124
|
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G |
Atp1b2 |
ATPase Na+/K+ transporting subunit beta 2 |
increases expression |
ISO |
Triiodothyronine results in increased expression of ATP1B2 mRNA |
CTD |
PMID:25172293 |
|
NCBI chr10:56,205,622...56,211,879
Ensembl chr10:56,205,625...56,211,891
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G |
Atp2a2 |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 |
multiple interactions increases expression |
EXP |
THRB protein promotes the reaction [Triiodothyronine results in increased expression of ATP2A2 mRNA]; Triiodothyronine inhibits the reaction [Phenylephrine results in decreased expression of ATP2A2 mRNA] |
CTD |
PMID:11577024 |
|
NCBI chr12:39,553,903...39,603,326
Ensembl chr12:39,553,903...39,603,326
|
|
G |
Avp |
arginine vasopressin |
multiple interactions |
EXP |
[AVP protein co-treated with Norepinephrine] inhibits the reaction [Triiodothyronine inhibits the reaction [EGF protein results in decreased expression of UCP1 mRNA]]; [AVP protein co-treated with Norepinephrine] inhibits the reaction [Triiodothyronine promotes the reaction [FGF1 protein results in increased expression of UCP1 mRNA]]; [AVP protein co-treated with Norepinephrine] inhibits the reaction [Triiodothyronine promotes the reaction [FGF2 protein results in increased expression of UCP1 mRNA]]; [AVP protein co-treated with Norepinephrine] inhibits the reaction [Triiodothyronine results in increased expression of UCP1 mRNA]; [EGF protein co-treated with AVP protein co-treated with Norepinephrine co-treated with Triiodothyronine] results in decreased expression of UCP1 mRNA; [FGF1 protein co-treated with AVP protein co-treated with Norepinephrine co-treated with Triiodothyronine] results in decreased expression of UCP1 mRNA; AVP protein inhibits the reaction [Triiodothyronine inhibits the reaction [EGF protein results in decreased expression of UCP1 mRNA]]; AVP protein inhibits the reaction [Triiodothyronine promotes the reaction [FGF1 protein results in increased expression of UCP1 mRNA]]; AVP protein inhibits the reaction [Triiodothyronine promotes the reaction [FGF2 protein results in increased expression of UCP1 mRNA]]; AVP protein inhibits the reaction [Triiodothyronine results in increased expression of UCP1 mRNA] |
CTD |
PMID:11742803 |
|
NCBI chr 3:123,117,482...123,119,460
Ensembl chr 3:123,117,492...123,119,460
|
|
G |
Bad |
BCL2-associated agonist of cell death |
decreases expression |
ISO EXP |
Triiodothyronine results in decreased expression of BAD protein |
CTD |
PMID:16021636 |
|
NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
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|
G |
Bax |
BCL2 associated X, apoptosis regulator |
decreases expression |
ISO EXP |
Triiodothyronine results in decreased expression of BAX protein |
CTD |
PMID:16021636 |
|
NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
|
|
G |
Bcl2 |
BCL2, apoptosis regulator |
multiple interactions increases expression |
ISO EXP |
Triiodothyronine promotes the reaction [tamibarotene results in decreased expression of BCL2 mRNA] Triiodothyronine results in increased expression of BCL2 protein |
CTD |
PMID:11201846 PMID:16021636 |
|
NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
|
|
G |
Bcl2a1 |
BCL2-related protein A1 |
multiple interactions |
ISO |
Triiodothyronine promotes the reaction [tamibarotene results in increased expression of BCL2A1A mRNA] |
CTD |
PMID:11201846 |
|
NCBI chr 8:96,551,424...96,559,527
Ensembl chr 8:96,551,245...96,559,483
|
|
G |
Bcl2l1 |
Bcl2-like 1 |
increases expression |
ISO EXP |
Triiodothyronine results in increased expression of BCL2L1 protein |
CTD |
PMID:16021636 |
|
NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
|
|
G |
Bcl3 |
BCL3, transcription coactivator |
increases expression |
EXP |
Triiodothyronine results in increased expression of BCL3 mRNA |
CTD |
PMID:22015988 |
|
NCBI chr 1:80,730,758...80,745,273
Ensembl chr 1:80,730,499...80,744,831
|
|
G |
Bmp2 |
bone morphogenetic protein 2 |
multiple interactions |
ISO |
[Triiodothyronine co-treated with Tetrachlorodibenzodioxin] results in decreased expression of BMP2 mRNA |
CTD |
PMID:14761676 |
|
NCBI chr 3:126,335,963...126,346,771
Ensembl chr 3:126,335,863...126,346,318
|
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G |
Bmp6 |
bone morphogenetic protein 6 |
multiple interactions decreases expression |
ISO |
4-OH-2',3,3',4',5'-pentachlorobiphenyl inhibits the reaction [Triiodothyronine results in decreased expression of BMP6 mRNA]; Polychlorinated Biphenyls inhibits the reaction [Triiodothyronine results in decreased expression of BMP6 mRNA]; Tetrachlorodibenzodioxin promotes the reaction [Triiodothyronine results in decreased expression of BMP6 mRNA] |
CTD |
PMID:14761676 |
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NCBI chr17:26,955,142...27,112,820
Ensembl chr17:26,955,142...27,112,820
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G |
Capns1 |
calpain, small subunit 1 |
multiple interactions |
ISO |
[Triiodothyronine co-treated with Tetrachlorodibenzodioxin] results in increased expression of CAPNS1 mRNA |
CTD |
PMID:14761676 |
|
NCBI chr 1:91,058,528...91,064,880
Ensembl chr 1:88,652,446...88,657,845
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G |
Casp3 |
caspase 3 |
decreases expression multiple interactions |
EXP ISO |
Triiodothyronine results in decreased expression of CASP3 protein THRA protein affects the reaction [Triiodothyronine inhibits the reaction [Silicon Dioxide results in increased cleavage of CASP3 protein]]; THRA protein affects the reaction [Triiodothyronine inhibits the reaction [Silicon Dioxide results in increased expression of CASP3 mRNA]]; Triiodothyronine inhibits the reaction [Silicon Dioxide results in increased cleavage of CASP3 protein]; Triiodothyronine inhibits the reaction [Silicon Dioxide results in increased expression of CASP3 mRNA] |
CTD |
PMID:16021636 PMID:32223187 |
|
NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
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G |
Cat |
catalase |
multiple interactions decreases activity |
EXP |
[Triiodothyronine co-treated with Hexachlorocyclohexane] results in decreased activity of CAT protein; gadolinium chloride inhibits the reaction [[Triiodothyronine co-treated with Hexachlorocyclohexane] results in decreased activity of CAT protein]; Resveratrol inhibits the reaction [Triiodothyronine results in decreased activity of CAT protein] |
CTD |
PMID:12516873 PMID:23391542 |
|
NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
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G |
Ccdc71 |
coiled-coil domain containing 71 |
decreases expression |
ISO |
Triiodothyronine results in decreased expression of CCDC71 mRNA |
CTD |
PMID:23397585 |
|
NCBI chr 8:117,236,933...117,251,573
Ensembl chr 8:117,246,376...117,250,280
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G |
Ccl5 |
C-C motif chemokine ligand 5 |
multiple interactions increases expression |
ISO |
4-OH-2',3,3',4',5'-pentachlorobiphenyl inhibits the reaction [Triiodothyronine results in increased expression of CCL5 mRNA]; Polychlorinated Biphenyls inhibits the reaction [Triiodothyronine results in increased expression of CCL5 mRNA]; Tetrachlorodibenzodioxin promotes the reaction [Triiodothyronine results in increased expression of CCL5 mRNA] |
CTD |
PMID:14761676 |
|
NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
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G |
Ccna2 |
cyclin A2 |
increases expression |
ISO EXP |
Triiodothyronine results in increased expression of CCNA2 protein |
CTD |
PMID:16021636 |
|
NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214
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G |
Ccnd1 |
cyclin D1 |
increases expression multiple interactions |
ISO EXP |
Triiodothyronine results in increased expression of CCND1 protein Triiodothyronine results in increased expression of CCND1 mRNA; Triiodothyronine results in increased expression of CCND1 protein THRB protein promotes the reaction [Triiodothyronine results in increased expression of CCND1 protein]; U 0126 inhibits the reaction [Triiodothyronine results in increased expression of CCND1 mRNA] |
CTD |
PMID:16021636 PMID:20638743 PMID:28315333 |
|
NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
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G |
Ccne1 |
cyclin E1 |
increases expression |
ISO EXP |
Triiodothyronine results in increased expression of CCNE1 protein Triiodothyronine results in increased expression of CCNE1 mRNA; Triiodothyronine results in increased expression of CCNE1 protein |
CTD |
PMID:16021636 |
|
NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980
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G |
Cdc45 |
cell division cycle 45 |
multiple interactions |
ISO |
[Triiodothyronine co-treated with Tetrachlorodibenzodioxin] results in decreased expression of CDC45 mRNA |
CTD |
PMID:14761676 |
|
NCBI chr11:86,328,785...86,354,099
Ensembl chr11:86,329,012...86,358,453
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
multiple interactions increases expression |
ISO |
[Triiodothyronine co-treated with Tetrachlorodibenzodioxin] results in increased expression of CDKN1A mRNA; Tetrachlorodibenzodioxin promotes the reaction [Triiodothyronine results in increased expression of CDKN1A mRNA]; Triiodothyronine analog inhibits the reaction [CDKN1A protein binds to PCNA protein]; Triiodothyronine inhibits the reaction [CDKN1A protein binds to PCNA protein] |
CTD |
PMID:14761676 PMID:22383522 |
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NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
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G |
Cdkn1b |
cyclin-dependent kinase inhibitor 1B |
decreases expression multiple interactions |
EXP ISO |
Triiodothyronine results in decreased expression of CDKN1B mRNA; Triiodothyronine results in decreased expression of CDKN1B protein THRB protein promotes the reaction [Triiodothyronine results in decreased expression of CDKN1B protein] |
CTD |
PMID:16021636 PMID:20638743 |
|
NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
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G |
Ces2c |
carboxylesterase 2C |
increases expression |
EXP |
Triiodothyronine results in increased expression of CES2C mRNA |
CTD |
PMID:28299817 |
|
NCBI chr 1:282,640,752...282,648,319
Ensembl chr 1:282,638,017...282,702,424
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G |
Cga |
glycoprotein hormones, alpha polypeptide |
multiple interactions decreases expression |
EXP |
Phenelzine inhibits the reaction [Triiodothyronine results in decreased expression of CGA mRNA]; Triiodothyronine inhibits the reaction [Phenelzine results in increased expression of CGA mRNA] |
CTD |
PMID:20148560 |
|
NCBI chr 5:50,362,491...50,393,368
Ensembl chr 5:50,381,244...50,393,367
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G |
Chek1 |
checkpoint kinase 1 |
increases phosphorylation |
ISO |
Triiodothyronine analog results in increased phosphorylation of CHEK1 protein |
CTD |
PMID:22383522 |
|
NCBI chr 8:39,181,162...39,201,588
Ensembl chr 8:39,181,163...39,243,882
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G |
Chst1 |
carbohydrate sulfotransferase 1 |
increases expression |
ISO |
Triiodothyronine results in increased expression of CHST1 mRNA |
CTD |
PMID:25172293 |
|
NCBI chr 3:81,441,785...81,512,829
Ensembl chr 3:81,498,022...81,512,807
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G |
Clu |
clusterin |
increases expression |
EXP |
Triiodothyronine results in increased expression of CLU mRNA |
CTD |
PMID:7531505 |
|
NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857
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G |
Col10a1 |
collagen type X alpha 1 chain |
multiple interactions increases expression |
EXP |
ciglitazone inhibits the reaction [Triiodothyronine results in increased expression of COL10A1 mRNA]; troglitazone inhibits the reaction [Triiodothyronine results in increased expression of COL10A1 mRNA] |
CTD |
PMID:16023420 |
|
NCBI chr20:41,180,295...41,190,664
Ensembl chr20:41,184,287...41,189,633
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G |
Col1a1 |
collagen type I alpha 1 chain |
multiple interactions increases expression |
EXP |
Triiodothyronine promotes the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA] Triiodothyronine results in increased expression of COL1A1 mRNA |
CTD |
PMID:18031379 |
|
NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
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G |
Col6a3 |
collagen type VI alpha 3 chain |
increases expression |
ISO |
Triiodothyronine results in increased expression of COL6A3 mRNA |
CTD |
PMID:15507505 |
|
NCBI chr 9:97,926,784...98,004,643
Ensembl chr 9:97,926,787...98,004,546
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G |
Coq10b |
coenzyme Q10B |
increases expression |
EXP |
Triiodothyronine results in increased expression of COQ10B mRNA |
CTD |
PMID:29357290 |
|
NCBI chr 9:61,655,963...61,675,880
Ensembl chr 9:61,655,963...61,675,873
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G |
Cox4i1 |
cytochrome c oxidase subunit 4i1 |
multiple interactions increases expression |
ISO |
Chloroquine promotes the reaction [Triiodothyronine results in increased expression of COX4I1 protein] |
CTD |
PMID:30209975 |
|
NCBI chr19:54,245,958...54,252,198
Ensembl chr19:54,245,950...54,252,225
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G |
Cpt1a |
carnitine palmitoyltransferase 1A |
increases expression multiple interactions |
ISO EXP |
Triiodothyronine results in increased expression of CPT1A mRNA Triiodothyronine results in increased expression of CPT1A mRNA; Triiodothyronine results in increased expression of CPT1A protein resveratrol promotes the reaction [Triiodothyronine results in increased expression of CPT1A mRNA] Resveratrol promotes the reaction [Triiodothyronine results in increased expression of CPT1A mRNA]; SIRT1 protein affects the reaction [Triiodothyronine results in increased expression of CPT1A mRNA]; SIRT1 protein affects the reaction [Triiodothyronine results in increased expression of CPT1A protein]; Triiodothyronine promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CPT1A mRNA] |
CTD |
PMID:23209300 PMID:25048947 |
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NCBI chr 1:218,568,157...218,629,679
Ensembl chr 1:218,569,510...218,629,678
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G |
Cpt1b |
carnitine palmitoyltransferase 1B |
increases expression |
ISO |
Triiodothyronine results in increased expression of CPT1B mRNA |
CTD |
PMID:30209975 |
|
NCBI chr 7:130,395,211...130,404,731
Ensembl chr 7:130,395,194...130,405,347
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G |
Cracr2b |
calcium release activated channel regulator 2B |
decreases expression |
ISO |
Triiodothyronine results in decreased expression of CRACR2B mRNA |
CTD |
PMID:23397585 |
|
NCBI chr 1:214,439,810...214,445,876
Ensembl chr 1:214,440,503...214,445,874 Ensembl chr 1:214,440,503...214,445,874
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G |
Crat |
carnitine O-acetyltransferase |
increases expression |
EXP |
Triiodothyronine results in increased expression of CRAT mRNA |
CTD |
PMID:15953391 |
|
NCBI chr 3:8,967,984...8,981,959
Ensembl chr 3:8,968,417...8,981,362
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G |
Csad |
cysteine sulfinic acid decarboxylase |
increases expression |
EXP |
Triiodothyronine results in increased expression of CSAD mRNA |
CTD |
PMID:15953391 |
|
NCBI chr 7:143,781,520...143,810,880
Ensembl chr 7:143,781,702...143,793,970
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G |
Csk |
C-terminal Src kinase |
multiple interactions |
ISO |
CSK protein promotes the reaction [Tetrachlorodibenzodioxin promotes the reaction [Triiodothyronine binds to THRA protein]] |
CTD |
PMID:9664232 |
|
NCBI chr 8:62,405,714...62,424,707
Ensembl chr 8:62,405,715...62,424,303
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G |
Ctse |
cathepsin E |
increases expression |
EXP |
Triiodothyronine results in increased expression of CTSE mRNA |
CTD |
PMID:15953391 |
|
NCBI chr13:48,426,833...48,449,493
Ensembl chr13:48,426,820...48,449,490
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G |
Cycs |
cytochrome c, somatic |
multiple interactions |
ISO |
THRA protein affects the reaction [Triiodothyronine inhibits the reaction [Silicon Dioxide results in increased expression of CYCS mRNA]]; Triiodothyronine inhibits the reaction [Silicon Dioxide results in increased expression of CYCS mRNA] |
CTD |
PMID:32223187 |
|
NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
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G |
Cyp11a1 |
cytochrome P450, family 11, subfamily a, polypeptide 1 |
multiple interactions |
ISO |
2,2',4,4'-tetrahydroxybenzophenone inhibits the reaction [Triiodothyronine promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP11A1 mRNA]]; 2,2',4,4'-tetrahydroxybenzophenone inhibits the reaction [Triiodothyronine promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP11A1 protein]]; Triiodothyronine promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP11A1 mRNA]; Triiodothyronine promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP11A1 protein] |
CTD |
PMID:21726595 |
|
NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
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G |
Cyp17a1 |
cytochrome P450, family 17, subfamily a, polypeptide 1 |
multiple interactions |
ISO |
2,2',4,4'-tetrahydroxybenzophenone inhibits the reaction [Triiodothyronine promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP17A1 mRNA]]; 2,2',4,4'-tetrahydroxybenzophenone inhibits the reaction [Triiodothyronine promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP17A1 protein]]; Triiodothyronine promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP17A1 mRNA]; Triiodothyronine promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP17A1 protein] |
CTD |
PMID:21726595 |
|
NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
multiple interactions increases expression |
ISO |
Triiodothyronine affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Triiodothyronine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein] Triiodothyronine results in increased expression of CYP1A1 mRNA |
CTD |
PMID:28478156 |
|
NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
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G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
increases expression multiple interactions |
ISO |
Triiodothyronine results in increased expression of CYP1A2 mRNA Triiodothyronine affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]; Triiodothyronine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 protein] |
CTD |
PMID:28478156 |
|
NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
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G |
Cyp24a1 |
cytochrome P450, family 24, subfamily a, polypeptide 1 |
increases expression multiple interactions |
ISO |
Triiodothyronine results in increased expression of CYP24A1 mRNA (4-(4-hydroxy-3-isopropyl-5-(4-nitrophenylethynyl)benzyl)-3,5-dimethylphenoxy)acetic acid inhibits the reaction [Triiodothyronine results in increased expression of CYP24A1 mRNA] |
CTD |
PMID:21815645 |
|
NCBI chr 3:168,097,484...168,111,920
Ensembl chr 3:168,097,485...168,111,920
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G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
increases activity increases expression |
EXP |
Triiodothyronine results in increased activity of CYP2E1 protein Triiodothyronine results in increased expression of CYP2E1 protein |
CTD |
PMID:14631868 |
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NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
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G |
Cyp3a62 |
cytochrome P450, family 3, subfamily a, polypeptide 62 |
increases expression multiple interactions |
ISO |
Triiodothyronine results in increased expression of CYP3A4 mRNA SJ 000311413 inhibits the reaction [Triiodothyronine results in increased expression of CYP3A4 mRNA] |
CTD |
PMID:21815645 |
|
NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397
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G |
Cyp8b1 |
cytochrome P450 family 8 subfamily B member 1 |
decreases expression |
EXP |
Triiodothyronine results in decreased expression of CYP8B1 mRNA |
CTD |
PMID:10393316 PMID:29357290 |
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NCBI chr 8:130,548,418...130,550,388
Ensembl chr 8:130,548,418...130,550,388
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G |
Dbp |
D-box binding PAR bZIP transcription factor |
increases expression |
ISO |
Triiodothyronine results in increased expression of DBP mRNA |
CTD |
PMID:25172293 |
|
NCBI chr 1:101,687,896...101,692,845
Ensembl chr 1:101,687,855...101,692,846
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G |
Decr2 |
2,4-dienoyl-CoA reductase 2 |
increases expression |
EXP |
Triiodothyronine results in increased expression of DECR2 mRNA |
CTD |
PMID:15953391 |
|
NCBI chr10:15,451,850...15,460,227
Ensembl chr10:15,431,638...15,465,413
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G |
Dio1 |
iodothyronine deiodinase 1 |
affects abundance multiple interactions increases expression affects metabolic processing increases chemical synthesis |
ISO EXP |
DIO1 gene SNP affects the abundance of Triiodothyronine 2,2',4,4'-tetrabromodiphenyl ether inhibits the reaction [Triiodothyronine results in increased expression of DIO1 mRNA] [DIO1 protein co-treated with DIO2 protein co-treated with DIO3 protein] affects the abundance of Triiodothyronine; [DIO1 protein results in increased metabolism of Thyroxine] which results in increased abundance of Triiodothyronine; Iodoacetates inhibits the reaction [[DIO1 protein results in increased metabolism of Thyroxine] which results in increased abundance of Triiodothyronine] DIO1 protein affects the metabolism of Triiodothyronine Arsenic affects the reaction [Triiodothyronine results in increased expression of DIO1 mRNA]; Pentachlorophenol inhibits the reaction [Triiodothyronine results in increased expression of DIO1 mRNA] DIO1 protein results in increased chemical synthesis of Triiodothyronine |
CTD |
PMID:15254343 PMID:16131326 PMID:17105838 PMID:18288313 PMID:21565810 PMID:23397585 PMID:24001430 PMID:25646720 PMID:27420076 PMID:28167136 PMID:29357290 |
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NCBI chr 5:126,894,837...126,911,532
Ensembl chr 5:126,895,286...126,911,520
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G |
Dio2 |
iodothyronine deiodinase 2 |
multiple interactions increases expression increases chemical synthesis |
ISO EXP |
2,2',4,4',5-brominated diphenyl ether inhibits the reaction [[DIO2 protein results in increased metabolism of Thyroxine] which results in increased chemical synthesis of Triiodothyronine]; 2,2',4,4',5-brominated diphenyl ether metabolite inhibits the reaction [[DIO2 protein results in increased metabolism of Thyroxine] which results in increased chemical synthesis of Triiodothyronine]; 2,2',4,4'-tetrabromodiphenyl ether metabolite inhibits the reaction [[DIO2 protein results in increased metabolism of Thyroxine] which results in increased chemical synthesis of Triiodothyronine]; [DIO1 protein co-treated with DIO2 protein co-treated with DIO3 protein] affects the abundance of Triiodothyronine; [DIO2 protein results in increased metabolism of Thyroxine] which results in increased chemical synthesis of Triiodothyronine; kaempferol promotes the reaction [DIO2 protein results in increased activity of and results in increased abundance of Triiodothyronine] Triiodothyronine results in increased expression of DIO2 mRNA DIO2 protein results in increased chemical synthesis of Triiodothyronine |
CTD |
PMID:17327447 PMID:17615150 PMID:23397585 PMID:25646720 PMID:26004626 |
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NCBI chr 6:114,475,156...114,489,443
Ensembl chr 6:114,476,142...114,476,723
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G |
Dio3 |
iodothyronine deiodinase 3 |
increases expression multiple interactions |
ISO |
Triiodothyronine results in increased expression of DIO3 mRNA [DIO1 protein co-treated with DIO2 protein co-treated with DIO3 protein] affects the abundance of Triiodothyronine |
CTD |
PMID:23397585 |
|
NCBI chr 6:134,627,278...134,629,139
Ensembl chr 6:134,627,278...134,629,138
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G |
Dmbt1 |
deleted in malignant brain tumors 1 |
multiple interactions |
ISO |
[Triiodothyronine co-treated with Tetrachlorodibenzodioxin] results in decreased expression of DMBT1 mRNA |
CTD |
PMID:14761676 |
|
NCBI chr 1:201,620,642...201,689,905 NCBI chr 1:203,149,414...203,228,705
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G |
Dmpk |
DM1 protein kinase |
increases expression |
EXP |
Triiodothyronine results in increased expression of DMPK mRNA |
CTD |
PMID:15953391 |
|
NCBI chr 1:79,988,096...79,999,358
Ensembl chr 1:79,989,019...79,999,364
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G |
Dmtn |
dematin actin binding protein |
increases expression |
ISO |
Triiodothyronine results in increased expression of DMTN mRNA |
CTD |
PMID:25172293 |
|
NCBI chr15:52,292,762...52,320,385
Ensembl chr15:52,292,765...52,320,385
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G |
Dusp2 |
dual specificity phosphatase 2 |
multiple interactions decreases expression |
ISO |
[Triiodothyronine co-treated with Tetrachlorodibenzodioxin] results in decreased expression of DUSP2 mRNA; Tetrachlorodibenzodioxin promotes the reaction [Triiodothyronine results in decreased expression of DUSP2 mRNA] |
CTD |
PMID:14761676 |
|
NCBI chr 3:119,776,925...119,779,110
Ensembl chr 3:119,776,925...119,779,099
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G |
Dync1li2 |
dynein, cytoplasmic 1 light intermediate chain 2 |
increases expression |
ISO |
Triiodothyronine results in increased expression of DYNC1LI2 mRNA |
CTD |
PMID:23397585 |
|
NCBI chr19:740,007...762,897
Ensembl chr19:740,028...762,897
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G |
Ech1 |
enoyl-CoA hydratase 1 |
increases expression |
EXP |
Triiodothyronine results in increased expression of ECH1 mRNA |
CTD |
PMID:15953391 |
|
NCBI chr 1:87,009,798...87,015,996
Ensembl chr 1:87,009,730...87,016,005
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G |
Efcab3 |
EF-hand calcium binding domain 3 |
decreases expression |
ISO |
Triiodothyronine results in decreased expression of EFCAB3 mRNA |
CTD |
PMID:23397585 |
|
NCBI chr10:93,304,559...93,332,849
Ensembl chr10:93,305,969...93,332,702
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G |
Egf |
epidermal growth factor |
multiple interactions |
EXP ISO |
[AVP protein co-treated with Norepinephrine] inhibits the reaction [Triiodothyronine inhibits the reaction [EGF protein results in decreased expression of UCP1 mRNA]]; [EGF protein co-treated with AVP protein co-treated with Norepinephrine co-treated with Triiodothyronine] results in decreased expression of UCP1 mRNA; AVP protein inhibits the reaction [Triiodothyronine inhibits the reaction [EGF protein results in decreased expression of UCP1 mRNA]]; Triiodothyronine inhibits the reaction [EGF protein results in decreased expression of UCP1 mRNA] Triiodothyronine inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]; Triiodothyronine inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:11742803 PMID:16150908 |
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NCBI chr 2:68,820,616...68,895,537
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G |
Eif4ebp1 |
eukaryotic translation initiation factor 4E binding protein 1 |
decreases phosphorylation |
ISO |
Triiodothyronine results in decreased phosphorylation of EIF4EBP1 protein |
CTD |
PMID:30209975 |
|
NCBI chr16:68,954,860...68,968,248
Ensembl chr16:68,954,875...68,968,248
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G |
Eml2 |
EMAP like 2 |
increases expression |
ISO |
Triiodothyronine results in increased expression of EML2 mRNA |
CTD |
PMID:23397585 |
|
NCBI chr 1:80,087,684...80,118,784
Ensembl chr 1:80,087,684...80,119,012
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G |
Eno1 |
enolase 1 |
increases expression |
ISO |
Triiodothyronine results in increased expression of ENO1 mRNA |
CTD |
PMID:15507505 |
|
NCBI chr 5:167,288,223...167,299,610
Ensembl chr 5:167,288,223...167,299,609
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G |
Epas1 |
endothelial PAS domain protein 1 |
increases expression |
ISO |
Triiodothyronine results in increased expression of EPAS1 mRNA |
CTD |
PMID:25172293 |
|
NCBI chr 6:10,306,508...10,385,239
Ensembl chr 6:10,306,405...10,387,265
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G |
Epb41l3 |
erythrocyte membrane protein band 4.1-like 3 |
multiple interactions |
ISO |
[Triiodothyronine co-treated with Tetrachlorodibenzodioxin] results in decreased expression of EPB41L3 mRNA |
CTD |
PMID:14761676 |
|
NCBI chr 9:117,314,935...117,666,408
Ensembl chr 9:117,538,009...117,666,410
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G |
Ereg |
epiregulin |
increases expression |
ISO |
Triiodothyronine results in increased expression of EREG mRNA |
CTD |
PMID:32816093 |
|
NCBI chr14:18,577,620...18,591,395
Ensembl chr14:18,576,355...18,591,394
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G |
Esr1 |
estrogen receptor 1 |
multiple interactions decreases expression |
ISO |
Tamoxifen inhibits the reaction [Triiodothyronine results in decreased expression of ESR1 mRNA] |
CTD |
PMID:19942988 |
|
NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
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|
G |
Esr2 |
estrogen receptor 2 |
multiple interactions |
EXP |
[Arsenic co-treated with Estradiol co-treated with Triiodothyronine] results in decreased expression of ESR2 mRNA; [bisphenol A co-treated with Estradiol co-treated with Triiodothyronine] results in increased expression of ESR2 mRNA; [bisphenol A co-treated with Zearalenone co-treated with Arsenic co-treated with enzacamene co-treated with Estradiol co-treated with Triiodothyronine] results in decreased expression of ESR2 mRNA; [bisphenol A results in increased susceptibility to [Estradiol co-treated with Triiodothyronine]] which results in increased expression of ESR2 mRNA; [enzacamene co-treated with Estradiol co-treated with Triiodothyronine] affects the expression of ESR2 mRNA; [Estradiol co-treated with Triiodothyronine] inhibits the reaction [bisphenol A results in decreased expression of ESR2 mRNA]; [Estradiol co-treated with Triiodothyronine] promotes the reaction [Zearalenone results in decreased expression of ESR2 mRNA]; [Zearalenone co-treated with Estradiol co-treated with Triiodothyronine] results in decreased expression of ESR2 mRNA; [Zearalenone results in increased susceptibility to [Estradiol co-treated with Triiodothyronine]] which results in decreased expression of ESR2 mRNA |
CTD |
PMID:27338438 |
|
NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
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G |
Ethe1 |
ETHE1, persulfide dioxygenase |
increases expression |
EXP |
Triiodothyronine results in increased expression of ETHE1 mRNA |
CTD |
PMID:28299817 |
|
NCBI chr 1:81,457,008...81,472,061
Ensembl chr 1:81,456,984...81,472,097
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G |
Eva1c |
eva-1 homolog C |
increases expression |
ISO |
Triiodothyronine results in increased expression of EVA1C mRNA |
CTD |
PMID:25172293 |
|
NCBI chr11:31,001,697...31,075,784
Ensembl chr11:31,002,451...31,075,809
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G |
Fabp4 |
fatty acid binding protein 4 |
increases expression |
EXP |
Triiodothyronine results in increased expression of FABP4 mRNA |
CTD |
PMID:15953391 |
|
NCBI chr 2:93,792,666...93,797,267
Ensembl chr 2:93,792,601...93,797,305
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G |
Fabp5 |
fatty acid binding protein 5 |
increases expression |
EXP |
Triiodothyronine results in increased expression of FABP5 mRNA |
CTD |
PMID:15953391 |
|
NCBI chr 2:93,981,662...93,985,322
Ensembl chr 2:93,981,656...93,985,378
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G |
Fads2 |
fatty acid desaturase 2 |
increases expression |
EXP |
Triiodothyronine results in increased expression of FADS2 mRNA |
CTD |
PMID:15953391 |
|
NCBI chr 1:225,906,582...226,152,568
Ensembl chr 1:226,114,413...226,152,524
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G |
Fam171b |
family with sequence similarity 171, member B |
decreases expression |
ISO |
Triiodothyronine results in decreased expression of FAM171B mRNA |
CTD |
PMID:23397585 |
|
NCBI chr 3:71,210,048...71,265,419
Ensembl chr 3:71,210,301...71,262,615
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G |
Fam83h |
family with sequence similarity 83, member H |
increases expression |
ISO |
Triiodothyronine results in increased expression of FAM83H mRNA |
CTD |
PMID:23397585 |
|
NCBI chr 7:117,062,748...117,070,936
Ensembl chr 7:117,062,692...117,070,936
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G |
Fasn |
fatty acid synthase |
increases expression |
EXP |
Triiodothyronine results in increased expression of FASN mRNA |
CTD |
PMID:15953391 |
|
NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
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G |
Fdft1 |
farnesyl diphosphate farnesyl transferase 1 |
increases expression |
EXP |
Triiodothyronine results in increased expression of FDFT1 mRNA |
CTD |
PMID:15953391 |
|
NCBI chr15:46,339,248...46,367,302
Ensembl chr15:46,339,249...46,367,302
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G |
Fdps |
farnesyl diphosphate synthase |
increases expression |
EXP |
Triiodothyronine results in increased expression of FDPS mRNA |
CTD |
PMID:15953391 |
|
NCBI chr 2:188,403,595...188,413,219
Ensembl chr 2:188,392,858...188,413,219
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G |
Fgf1 |
fibroblast growth factor 1 |
multiple interactions |
EXP |
[AVP protein co-treated with Norepinephrine] inhibits the reaction [Triiodothyronine promotes the reaction [FGF1 protein results in increased expression of UCP1 mRNA]]; [FGF1 protein co-treated with AVP protein co-treated with Norepinephrine co-treated with Triiodothyronine] results in decreased expression of UCP1 mRNA; AVP protein inhibits the reaction [Triiodothyronine promotes the reaction [FGF1 protein results in increased expression of UCP1 mRNA]]; Triiodothyronine promotes the reaction [FGF1 protein results in increased expression of UCP1 mRNA] |
CTD |
PMID:11742803 |
|
NCBI chr18:32,273,830...32,359,831
Ensembl chr18:32,273,770...32,359,824
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G |
Fgf18 |
fibroblast growth factor 18 |
multiple interactions |
ISO |
Triiodothyronine promotes the reaction [FGF18 protein results in increased phosphorylation of MAPK1 protein]; Triiodothyronine promotes the reaction [FGF18 protein results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:16150908 |
|
NCBI chr10:18,047,109...18,082,290
Ensembl chr10:18,047,109...18,063,391
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G |
Fgf2 |
fibroblast growth factor 2 |
multiple interactions |
ISO EXP |
Triiodothyronine inhibits the reaction [FGF2 protein results in increased phosphorylation of STAT1 protein]; Triiodothyronine promotes the reaction [FGF2 protein results in increased phosphorylation of MAPK1 protein]; Triiodothyronine promotes the reaction [FGF2 protein results in increased phosphorylation of MAPK3 protein] [AVP protein co-treated with Norepinephrine] inhibits the reaction [Triiodothyronine promotes the reaction [FGF2 protein results in increased expression of UCP1 mRNA]]; AVP protein inhibits the reaction [Triiodothyronine promotes the reaction [FGF2 protein results in increased expression of UCP1 mRNA]]; Triiodothyronine promotes the reaction [FGF2 protein promotes the reaction [FGFR1 protein results in increased phosphorylation of FGFR1 protein]]; Triiodothyronine promotes the reaction [FGF2 protein results in increased expression of UCP1 mRNA]; Triiodothyronine promotes the reaction [FGF2 protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Triiodothyronine promotes the reaction [FGF2 protein results in increased phosphorylation of and results in increased activity of MAPK3 protein] |
CTD |
PMID:11742803 PMID:12805413 PMID:16150908 |
|
NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
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G |
Fgf7 |
fibroblast growth factor 7 |
decreases expression |
ISO |
Triiodothyronine results in decreased expression of FGF7 mRNA |
CTD |
PMID:15507505 |
|
NCBI chr 3:118,315,859...118,368,464
Ensembl chr 3:118,317,761...118,366,872
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G |
Fgf9 |
fibroblast growth factor 9 |
multiple interactions |
ISO |
Triiodothyronine promotes the reaction [FGF9 protein results in increased phosphorylation of MAPK1 protein]; Triiodothyronine promotes the reaction [FGF9 protein results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:16150908 |
|
NCBI chr15:38,341,657...38,386,945
Ensembl chr15:38,341,089...38,387,316
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G |
Fgfr1 |
Fibroblast growth factor receptor 1 |
increases expression multiple interactions |
ISO EXP |
Triiodothyronine results in increased expression of FGFR1 mRNA Triiodothyronine results in increased expression of FGFR1 mRNA; Triiodothyronine results in increased expression of FGFR1 protein Cycloheximide inhibits the reaction [Triiodothyronine results in increased expression of FGFR1 mRNA]; Dactinomycin inhibits the reaction [Triiodothyronine results in increased expression of FGFR1 mRNA]; Triiodothyronine promotes the reaction [FGF2 protein promotes the reaction [FGFR1 protein results in increased phosphorylation of FGFR1 protein]] |
CTD |
PMID:12805413 PMID:16150908 |
|
NCBI chr16:71,265,390...71,319,046
Ensembl chr16:71,266,248...71,319,449
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G |
Fgfr2 |
fibroblast growth factor receptor 2 |
increases expression |
ISO |
Triiodothyronine results in increased expression of FGFR2 mRNA |
CTD |
PMID:16150908 |
|
NCBI chr 1:200,590,951...200,696,946
Ensembl chr 1:200,590,953...200,696,928
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G |
Fgfr3 |
fibroblast growth factor receptor 3 |
increases expression |
ISO |
Triiodothyronine results in increased expression of FGFR3 mRNA |
CTD |
PMID:16150908 |
|
NCBI chr14:82,272,322...82,287,739
Ensembl chr14:82,273,070...82,287,706
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G |
Fkbp10 |
FKBP prolyl isomerase 10 |
decreases expression |
ISO |
Triiodothyronine results in decreased expression of FKBP10 mRNA |
CTD |
PMID:23397585 |
|
NCBI chr10:88,326,337...88,338,199
Ensembl chr10:88,326,080...88,338,207
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G |
Flrt1 |
fibronectin leucine rich transmembrane protein 1 |
increases expression |
ISO |
Triiodothyronine results in increased expression of FLRT1 mRNA |
CTD |
PMID:25172293 |
|
NCBI chr 1:222,340,481...222,417,915
Ensembl chr 1:222,344,713...222,350,173
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G |
Foxo6 |
forkhead box O6 |
increases expression |
ISO |
Triiodothyronine results in increased expression of FOXO6 mRNA |
CTD |
PMID:25172293 |
|
NCBI chr 5:139,208,153...139,227,288
Ensembl chr 5:139,208,046...139,227,196
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G |
Fpgs |
folylpolyglutamate synthase |
increases expression |
EXP |
Triiodothyronine results in increased expression of FPGS mRNA |
CTD |
PMID:15953391 |
|
NCBI chr 3:11,717,667...11,729,694
Ensembl chr 3:11,717,667...11,723,327
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G |
Fshb |
follicle stimulating hormone subunit beta |
multiple interactions |
EXP |
FSHB protein promotes the reaction [Triiodothyronine results in increased expression of INHBB mRNA]; Triiodothyronine promotes the reaction [FSHB protein results in increased expression of INHBB mRNA] |
CTD |
PMID:7531505 |
|
NCBI chr 3:98,088,321...98,092,131
Ensembl chr 3:98,088,324...98,092,131
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G |
Fxyd2 |
FXYD domain-containing ion transport regulator 2 |
increases expression |
EXP |
Triiodothyronine results in increased expression of FXYD2 mRNA |
CTD |
PMID:15953391 |
|
NCBI chr 8:49,710,334...49,717,492
Ensembl chr 8:49,710,477...49,716,955
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G |
G6pc1 |
glucose-6-phosphatase catalytic subunit 1 |
multiple interactions increases expression |
ISO |
(4-(4-hydroxy-3-isopropyl-5-(4-nitrophenylethynyl)benzyl)-3,5-dimethylphenoxy)acetic acid inhibits the reaction [Triiodothyronine results in increased expression of G6PC1 mRNA]; SJ 000311413 inhibits the reaction [Triiodothyronine results in increased expression of G6PC1 mRNA] |
CTD |
PMID:21815645 |
|
NCBI chr10:89,286,009...89,296,213
Ensembl chr10:89,285,855...89,296,213
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G |
Gap43 |
growth associated protein 43 |
increases expression |
EXP |
Triiodothyronine results in increased expression of GAP43 mRNA; Triiodothyronine results in increased expression of GAP43 protein |
CTD |
PMID:15708448 |
|
NCBI chr11:58,624,198...58,717,916
Ensembl chr11:58,624,198...58,717,914
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G |
Gba |
glucosylceramidase beta |
increases activity |
EXP |
Triiodothyronine results in increased activity of GBA protein |
CTD |
PMID:9101438 |
|
NCBI chr 2:188,511,781...188,522,602
Ensembl chr 2:188,516,582...188,522,601
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G |
Gch1 |
GTP cyclohydrolase 1 |
increases expression |
EXP |
Triiodothyronine results in increased expression of GCH1 mRNA |
CTD |
PMID:15953391 |
|
NCBI chr15:23,935,011...23,968,971
Ensembl chr15:23,934,585...23,969,011
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G |
Gh1 |
growth hormone 1 |
multiple interactions increases expression |
EXP ISO |
Alitretinoin promotes the reaction [Triiodothyronine results in increased expression of GH1 mRNA]; Amiodarone inhibits the reaction [Triiodothyronine results in increased expression of GH1 mRNA]; bisphenol A promotes the reaction [Triiodothyronine results in increased expression of and results in increased secretion of GH protein]; Butyric Acid inhibits the reaction [Triiodothyronine results in increased expression of GH1 mRNA]; Dexamethasone promotes the reaction [Triiodothyronine results in increased expression of GH1 mRNA]; Edetic Acid promotes the reaction [Triiodothyronine results in increased expression of GH1 mRNA]; P4HB protein inhibits the reaction [Triiodothyronine results in increased expression of and results in increased secretion of GH protein]; P4HB protein inhibits the reaction [Triiodothyronine results in increased expression of GH mRNA]; P4HB protein inhibits the reaction [Triiodothyronine results in increased expression of GH1 mRNA]; P4HB protein inhibits the reaction [Triiodothyronine results in increased expression of GH1 protein]; Pentetic Acid promotes the reaction [Alitretinoin promotes the reaction [Triiodothyronine results in increased expression of GH1 mRNA]]; Pentetic Acid promotes the reaction [Tretinoin promotes the reaction [Triiodothyronine results in increased expression of GH1 mRNA]]; Pentetic Acid promotes the reaction [Triiodothyronine promotes the reaction [Alitretinoin results in increased expression of GH1 mRNA]]; Pentetic Acid promotes the reaction [Triiodothyronine promotes the reaction [Tretinoin results in increased expression of GH1 mRNA]]; Pentetic Acid promotes the reaction [Triiodothyronine results in increased expression of GH1 mRNA]; Polybrominated Biphenyls analog inhibits the reaction [Triiodothyronine results in increased expression of GH1 mRNA]; Polybrominated Biphenyls analog inhibits the reaction [Triiodothyronine results in increased expression of GH1 protein]; Tretinoin promotes the reaction [Triiodothyronine results in increased expression of GH1 mRNA]; Triiodothyronine promotes the reaction [Alitretinoin results in increased expression of GH1 mRNA]; Triiodothyronine promotes the reaction [Tretinoin results in increased expression of GH1 mRNA]; Triiodothyronine results in increased expression of and results in increased secretion of GH protein; Zinc inhibits the reaction [Pentetic Acid promotes the reaction [Alitretinoin promotes the reaction [Triiodothyronine results in increased expression of GH1 mRNA]]]; Zinc inhibits the reaction [Pentetic Acid promotes the reaction [Tretinoin promotes the reaction [Triiodothyronine results in increased expression of GH1 mRNA]]]; Zinc inhibits the reaction [Pentetic Acid promotes the reaction [Triiodothyronine promotes the reaction [Alitretinoin results in increased expression of GH1 mRNA]]]; Zinc inhibits the reaction [Pentetic Acid promotes the reaction [Triiodothyronine promotes the reaction [Tretinoin results in increased expression of GH1 mRNA]]]; Zinc inhibits the reaction [Pentetic Acid promotes the reaction [Triiodothyronine results in increased expression of GH1 mRNA]] Triiodothyronine results in increased expression of GH mRNA; Triiodothyronine results in increased expression of GH1 mRNA; Triiodothyronine results in increased expression of GH1 protein |
CTD |
PMID:2211641 PMID:2910914 PMID:10720163 PMID:15240998 PMID:17090972 PMID:17928132 PMID:22201216 PMID:24001430 PMID:27420076 |
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NCBI chr10:94,486,204...94,488,181
Ensembl chr10:94,486,205...94,488,180
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G |
Ghrh |
growth hormone releasing hormone |
multiple interactions |
EXP |
Triiodothyronine promotes the reaction [Dexamethasone results in increased expression of GHRH mRNA] |
CTD |
PMID:17090972 |
|
NCBI chr 3:153,449,124...153,468,794
Ensembl chr 3:153,449,125...153,468,794
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G |
Gja1 |
gap junction protein, alpha 1 |
increases expression |
EXP |
Triiodothyronine results in increased expression of GJA1 protein |
CTD |
PMID:15685554 |
|
NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
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G |
Gpcpd1 |
glycerophosphocholine phosphodiesterase 1 |
increases expression |
EXP |
Triiodothyronine results in increased expression of GPCPD1 mRNA |
CTD |
PMID:15953391 |
|
NCBI chr 3:125,169,131...125,213,598
Ensembl chr 3:125,169,135...125,213,607
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G |
Gpd2 |
glycerol-3-phosphate dehydrogenase 2 |
increases expression |
EXP |
Triiodothyronine results in increased expression of GPD2 mRNA |
CTD |
PMID:29357290 |
|
NCBI chr 3:43,223,892...43,359,069
Ensembl chr 3:43,255,567...43,359,074
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G |
Grik4 |
glutamate ionotropic receptor kainate type subunit 4 |
increases expression |
ISO |
Triiodothyronine results in increased expression of GRIK4 mRNA |
CTD |
PMID:23397585 |
|
NCBI chr 8:46,804,134...47,237,546
Ensembl chr 8:46,806,147...47,094,352
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G |
Gsta2 |
glutathione S-transferase alpha 2 |
multiple interactions |
EXP |
Triiodothyronine inhibits the reaction [goitrin results in increased expression of GSTA2 protein] |
CTD |
PMID:7532609 |
|
NCBI chr 8:85,640,081...85,645,621
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G |
Gstp1 |
glutathione S-transferase pi 1 |
multiple interactions |
EXP |
Triiodothyronine inhibits the reaction [goitrin results in increased expression of GSTP1 protein] |
CTD |
PMID:7532609 |
|
NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
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G |
Gulp1 |
GULP PTB domain containing engulfment adaptor 1 |
decreases expression |
ISO |
Triiodothyronine results in decreased expression of GULP1 mRNA |
CTD |
PMID:23397585 |
|
NCBI chr 9:51,263,484...51,538,066
Ensembl chr 9:51,263,622...51,538,072
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G |
H1f5 |
H1.5 linker histone, cluster member |
increases expression |
ISO |
Triiodothyronine results in increased expression of H1-5 mRNA |
CTD |
PMID:23397585 |
|
NCBI chr17:44,766,313...44,766,981
Ensembl chr17:44,766,313...44,766,981
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G |
H2ax |
H2A.X variant histone |
increases phosphorylation multiple interactions |
ISO |
Triiodothyronine analog results in increased phosphorylation of H2AX protein Triiodothyronine analog promotes the reaction [Cisplatin results in increased expression of H2AX protein] |
CTD |
PMID:22383522 |
|
NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
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G |
Hba-a1 |
hemoglobin alpha, adult chain 1 |
increases expression |
EXP |
Triiodothyronine results in increased expression of HBA-A1 mRNA |
CTD |
PMID:15953391 |
|
NCBI chr10:15,602,794...15,603,649
Ensembl chr10:15,602,794...15,603,649
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G |
Hbb |
hemoglobin subunit beta |
increases expression |
EXP |
Triiodothyronine results in increased expression of HBB mRNA |
CTD |
PMID:15953391 |
|
NCBI chr 1:168,971,269...168,972,680
Ensembl chr 1:168,971,274...168,972,725
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G |
Hbg1 |
hemoglobin subunit gamma 1 |
increases expression |
EXP |
Triiodothyronine results in increased expression of HBG1 mRNA |
CTD |
PMID:15953391 |
|
NCBI chr 1:168,992,841...168,994,219
Ensembl chr 1:168,992,722...168,994,253
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G |
Hcn2 |
hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 |
increases expression |
ISO |
Triiodothyronine results in increased expression of HCN2 mRNA |
CTD |
PMID:25172293 |
|
NCBI chr 7:12,851,730...12,870,087
Ensembl chr 7:12,851,739...12,874,215
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G |
Hdc |
histidine decarboxylase |
decreases expression |
EXP |
Triiodothyronine results in decreased expression of HDC mRNA |
CTD |
PMID:29357290 |
|
NCBI chr 3:119,057,524...119,075,599
Ensembl chr 3:119,057,517...119,075,619
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G |
Heg1 |
heart development protein with EGF-like domains 1 |
increases expression |
ISO |
Triiodothyronine results in increased expression of HEG1 mRNA |
CTD |
PMID:25172293 |
|
NCBI chr11:70,234,248...70,322,966
Ensembl chr11:70,236,888...70,322,690
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G |
Hif1a |
hypoxia inducible factor 1 subunit alpha |
increases expression |
ISO |
Triiodothyronine results in increased expression of HIF1A mRNA |
CTD |
PMID:15507505 |
|
NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
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G |
Higd1a |
HIG1 hypoxia inducible domain family, member 1A |
increases expression |
EXP |
Triiodothyronine results in increased expression of HIGD1A mRNA |
CTD |
PMID:15953391 |
|
NCBI chr 8:130,482,492...130,491,888
Ensembl chr 8:130,482,493...130,491,998
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G |
Hira |
histone cell cycle regulator |
increases expression |
ISO |
Triiodothyronine results in increased expression of HIRA mRNA |
CTD |
PMID:23397585 |
|
NCBI chr11:86,168,196...86,276,430
Ensembl chr11:86,168,196...86,276,430
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|
G |
Hmgcs1 |
3-hydroxy-3-methylglutaryl-CoA synthase 1 |
increases expression |
EXP |
Triiodothyronine results in increased expression of HMGCS1 mRNA |
CTD |
PMID:15953391 |
|
NCBI chr 2:52,427,351...52,445,082
Ensembl chr 2:52,431,601...52,445,055
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G |
Hmgcs2 |
3-hydroxy-3-methylglutaryl-CoA synthase 2 |
increases expression |
ISO |
Triiodothyronine results in increased expression of HMGCS2 mRNA |
CTD |
PMID:23397585 |
|
NCBI chr 2:200,452,623...200,480,785
Ensembl chr 2:200,452,624...200,479,423
|
|
G |
Hnrnph3 |
heterogeneous nuclear ribonucleoprotein H3 |
increases expression |
ISO |
Triiodothyronine results in increased expression of HNRNPH3 mRNA |
CTD |
PMID:23397585 |
|
NCBI chr20:27,167,926...27,178,172
Ensembl chr20:27,169,267...27,216,941
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G |
Hr |
HR, lysine demethylase and nuclear receptor corepressor |
increases expression |
ISO |
Triiodothyronine results in increased expression of HR mRNA |
CTD |
PMID:25172293 PMID:26096596 |
|
NCBI chr15:52,241,801...52,261,276
Ensembl chr15:52,241,801...52,261,276
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|
G |
Hscb |
HscB mitochondrial iron-sulfur cluster co-chaperone |
decreases expression |
ISO |
Triiodothyronine results in decreased expression of HSCB mRNA |
CTD |
PMID:23397585 |
|
NCBI chr12:51,878,267...51,888,645
Ensembl chr12:51,878,153...51,888,669
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|
G |
Hsd3b1 |
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 |
multiple interactions |
ISO |
2,2',4,4'-tetrahydroxybenzophenone inhibits the reaction [Triiodothyronine inhibits the reaction [[NR4A1 co-treated with THRA] results in increased expression of HSD3B1 mRNA]]; 2,2',4,4'-tetrahydroxybenzophenone inhibits the reaction [Triiodothyronine promotes the reaction [[NR4A1 co-treated with THRA] results in increased expression of HSD3B1 mRNA]]; Triiodothyronine inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of HSD3B1 mRNA]; Triiodothyronine inhibits the reaction [[NR4A1 co-treated with THRA] results in increased expression of HSD3B1 mRNA]; Triiodothyronine promotes the reaction [[NR4A1 co-treated with THRA] results in increased expression of HSD3B1 mRNA] |
CTD |
PMID:21726595 |
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G |
Hunk |
hormonally upregulated Neu-associated kinase |
increases expression |
ISO |
Triiodothyronine results in increased expression of HUNK mRNA |
CTD |
PMID:25172293 |
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NCBI chr11:30,550,141...30,663,465
Ensembl chr11:30,550,141...30,663,465
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G |
Idh1 |
isocitrate dehydrogenase (NADP(+)) 1 |
increases expression |
EXP |
Triiodothyronine results in increased expression of IDH1 mRNA |
CTD |
PMID:15953391 |
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NCBI chr 9:71,882,108...71,911,645
Ensembl chr 9:71,882,105...71,900,044
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G |
Igf1 |
insulin-like growth factor 1 |
multiple interactions increases expression increases secretion |
EXP |
Estradiol inhibits the reaction [Triiodothyronine results in increased expression of IGF1 mRNA]; Estradiol inhibits the reaction [Triiodothyronine results in increased secretion of IGF1 protein] |
CTD |
PMID:7684602 |
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NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
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G |
Igfbp2 |
insulin-like growth factor binding protein 2 |
increases expression |
EXP |
Triiodothyronine results in increased expression of IGFBP2 mRNA |
CTD |
PMID:15953391 |
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NCBI chr 9:80,118,029...80,144,804
Ensembl chr 9:80,118,029...80,144,789
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G |
Iglon5 |
IgLON family member 5 |
increases expression |
ISO |
Triiodothyronine results in increased expression of IGLON5 mRNA |
CTD |
PMID:25172293 |
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NCBI chr 1:98,440,186...98,457,942
Ensembl chr 1:98,440,186...98,455,920
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G |
Il1a |
interleukin 1 alpha |
increases expression |
ISO |
Triiodothyronine results in increased expression of IL1A mRNA |
CTD |
PMID:32816093 |
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NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
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G |
Il1b |
interleukin 1 beta |
multiple interactions increases expression |
ISO |
THRA protein affects the reaction [Triiodothyronine inhibits the reaction [Silicon Dioxide results in increased expression of IL1B mRNA]]; THRA protein affects the reaction [Triiodothyronine inhibits the reaction [Silicon Dioxide results in increased secretion of IL1B protein]]; Triiodothyronine inhibits the reaction [Silicon Dioxide results in increased expression of IL1B mRNA]; Triiodothyronine inhibits the reaction [Silicon Dioxide results in increased secretion of IL1B protein] Triiodothyronine results in increased expression of IL1B mRNA |
CTD |
PMID:32223187 PMID:32816093 |
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NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
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G |
Il24 |
interleukin 24 |
increases expression |
ISO |
Triiodothyronine results in increased expression of IL24 mRNA |
CTD |
PMID:32816093 |
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NCBI chr13:47,618,451...47,623,849
Ensembl chr13:47,618,452...47,623,849
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G |
Il6 |
interleukin 6 |
multiple interactions |
ISO |
THRA protein affects the reaction [Triiodothyronine inhibits the reaction [Silicon Dioxide results in increased expression of IL6 mRNA]]; THRA protein affects the reaction [Triiodothyronine inhibits the reaction [Silicon Dioxide results in increased secretion of IL6 protein]]; Triiodothyronine inhibits the reaction [Silicon Dioxide results in increased expression of IL6 mRNA]; Triiodothyronine inhibits the reaction [Silicon Dioxide results in increased secretion of IL6 protein] |
CTD |
PMID:32223187 |
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NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
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G |
Inhbb |
inhibin subunit beta B |
multiple interactions increases expression |
EXP |
FSHB protein promotes the reaction [Triiodothyronine results in increased expression of INHBB mRNA]; Triiodothyronine promotes the reaction [FSHB protein results in increased expression of INHBB mRNA] |
CTD |
PMID:7531505 |
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NCBI chr13:35,436,532...35,442,222
Ensembl chr13:35,436,532...35,442,222
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G |
Ins2 |
insulin 2 |
multiple interactions |
ISO |
[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein co-treated with Indomethacin co-treated with Rosiglitazone co-treated with Triiodothyronine] results in increased expression of KCNMA1 mRNA; [Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein co-treated with Indomethacin co-treated with Rosiglitazone co-treated with Triiodothyronine] results in increased expression of KCNMA1 protein; [Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein co-treated with Indomethacin co-treated with Rosiglitazone co-treated with Triiodothyronine] results in increased expression of SLC2A4 mRNA; [Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein co-treated with Indomethacin co-treated with Rosiglitazone co-treated with Triiodothyronine] results in increased expression of SLC2A4 protein |
CTD |
PMID:27605626 |
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NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
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G |
Insig1 |
insulin induced gene 1 |
increases expression |
EXP |
Triiodothyronine results in increased expression of INSIG1 mRNA |
CTD |
PMID:15953391 |
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NCBI chr 4:342,302...350,515
Ensembl chr 4:342,302...350,515
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G |
Irf1 |
interferon regulatory factor 1 |
multiple interactions |
ISO |
[Triiodothyronine co-treated with Tetrachlorodibenzodioxin] results in increased expression of IRF1 mRNA |
CTD |
PMID:14761676 |
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NCBI chr10:39,109,530...39,116,532
Ensembl chr10:39,109,522...39,116,531
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G |
Itgam |
integrin subunit alpha M |
multiple interactions |
ISO |
Triiodothyronine promotes the reaction [tamibarotene results in increased expression of ITGAM protein] |
CTD |
PMID:11201846 |
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NCBI chr 1:199,495,312...199,545,738
Ensembl chr 1:199,495,298...199,623,960
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G |
Itgb3 |
integrin subunit beta 3 |
multiple interactions |
ISO |
ITGB3 inhibits the reaction [bisphenol A inhibits the reaction [Triiodothyronine inhibits the reaction [NCOR1 protein binds to and results in decreased activity of THRB protein]]]; ITGB3 inhibits the reaction [bisphenol A inhibits the reaction [Triiodothyronine inhibits the reaction [NCOR2 protein binds to and results in decreased activity of THRB protein]]] |
CTD |
PMID:22227104 |
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NCBI chr10:92,667,869...92,783,413
Ensembl chr10:92,667,869...92,783,410
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G |
Itgb5 |
integrin subunit beta 5 |
increases expression decreases expression |
ISO |
Triiodothyronine results in increased expression of ITGB5 mRNA Triiodothyronine results in decreased expression of ITGB5 mRNA |
CTD |
PMID:23397585 |
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NCBI chr11:70,056,500...70,172,164
Ensembl chr11:70,056,500...70,172,372
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G |
Itpk1 |
inositol-tetrakisphosphate 1-kinase |
increases expression |
ISO |
Triiodothyronine results in increased expression of ITPK1 mRNA |
CTD |
PMID:25172293 |
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NCBI chr 6:126,448,920...126,582,188
Ensembl chr 6:126,450,139...126,582,134
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G |
Itpr1 |
inositol 1,4,5-trisphosphate receptor, type 1 |
increases expression |
EXP |
Triiodothyronine results in increased expression of ITPR1 mRNA |
CTD |
PMID:15953391 |
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NCBI chr 4:140,247,297...140,580,749
Ensembl chr 4:140,247,313...140,580,748
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G |
Kantr |
KDM5C adjacent transcript |
increases expression |
ISO |
Triiodothyronine results in increased expression of KANTR mRNA |
CTD |
PMID:25172293 |
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NCBI chr X:22,369,521...22,399,881
Ensembl chr X:22,369,521...22,399,901
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G |
Kcna1 |
potassium voltage-gated channel subfamily A member 1 |
increases expression |
ISO |
Triiodothyronine results in increased expression of KCNA1 mRNA |
CTD |
PMID:25172293 |
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NCBI chr 4:159,190,781...159,192,526
Ensembl chr 4:159,190,804...159,192,526
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G |
Kcna4 |
potassium voltage-gated channel subfamily A member 4 |
decreases expression |
ISO |
Triiodothyronine results in decreased expression of KCNA4 mRNA |
CTD |
PMID:25172293 |
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NCBI chr 3:98,293,295...98,300,763
Ensembl chr 3:98,297,554...98,300,680
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G |
Kcnma1 |
potassium calcium-activated channel subfamily M alpha 1 |
multiple interactions |
ISO |
[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein co-treated with Indomethacin co-treated with rosiglitazone co-treated with Triiodothyronine] results in increased expression of KCNMA1 mRNA; [Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein co-treated with Indomethacin co-treated with rosiglitazone co-treated with Triiodothyronine] results in increased expression of KCNMA1 protein |
CTD |
PMID:27605626 |
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NCBI chr15:344,204...1,048,849
Ensembl chr15:344,360...1,047,956
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G |
Kctd12 |
potassium channel tetramerization domain containing 12 |
decreases expression |
ISO |
Triiodothyronine results in decreased expression of KCTD12 mRNA |
CTD |
PMID:25172293 |
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NCBI chr15:87,384,632...87,390,627
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G |
Kif1b |
kinesin family member 1B |
increases expression |
EXP |
Triiodothyronine results in increased expression of KIF1B mRNA |
CTD |
PMID:15953391 |
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NCBI chr 5:165,994,803...166,133,497
Ensembl chr 5:165,938,576...166,133,491
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G |
Klf9 |
Kruppel-like factor 9 |
decreases expression increases expression |
ISO |
Triiodothyronine results in decreased expression of KLF9 mRNA Triiodothyronine results in increased expression of KLF9 mRNA |
CTD |
PMID:15507505 PMID:23397585 PMID:26096596 |
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NCBI chr 1:240,908,483...240,933,198
Ensembl chr 1:240,908,483...240,933,198
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G |
Krt13 |
keratin 13 |
multiple interactions |
ISO |
[Triiodothyronine co-treated with Tetrachlorodibenzodioxin] results in decreased expression of KRT13 mRNA |
CTD |
PMID:14761676 |
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NCBI chr10:88,032,130...88,036,040
Ensembl chr10:88,032,130...88,036,040
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G |
Ldlr |
low density lipoprotein receptor |
multiple interactions increases expression |
ISO EXP |
Amiodarone promotes the reaction [Triiodothyronine results in increased expression of LDLR mRNA]; desethylamiodarone promotes the reaction [Triiodothyronine results in increased expression of LDLR mRNA] Triiodothyronine inhibits the reaction [Amiodarone results in decreased expression of LDLR protein] |
CTD |
PMID:9071962 PMID:9712728 |
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NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903
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G |
Lgi4 |
leucine-rich repeat LGI family, member 4 |
increases expression |
ISO |
Triiodothyronine results in increased expression of LGI4 mRNA |
CTD |
PMID:25172293 |
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NCBI chr 1:89,491,588...89,502,939
Ensembl chr 1:89,491,654...89,502,974
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G |
Lhx3 |
LIM homeobox 3 |
decreases expression |
ISO |
Triiodothyronine results in decreased expression of LHX3 mRNA |
CTD |
PMID:23397585 |
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NCBI chr 3:3,653,861...3,662,509
Ensembl chr 3:3,654,755...3,661,810
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G |
Linc00176 |
long intergenic non-protein coding RNA 176 |
decreases expression |
ISO |
Triiodothyronine results in decreased expression of C20ORF204 mRNA |
CTD |
PMID:23397585 |
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NCBI chr 3:177,163,038...177,166,874
Ensembl chr 3:177,164,359...177,166,737
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G |
Lipe |
lipase E, hormone sensitive type |
increases expression |
ISO |
Triiodothyronine results in increased expression of LIPE mRNA |
CTD |
PMID:30209975 |
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NCBI chr 1:82,248,031...82,266,727
Ensembl chr 1:82,248,046...82,266,727
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G |
Lmcd1 |
LIM and cysteine-rich domains 1 |
decreases expression |
ISO |
Triiodothyronine results in decreased expression of LMCD1 mRNA |
CTD |
PMID:25172293 |
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NCBI chr 4:144,192,989...144,252,554
Ensembl chr 4:144,192,989...144,252,551
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G |
Lpin3 |
lipin 3 |
increases expression |
ISO |
Triiodothyronine results in increased expression of LPIN3 mRNA |
CTD |
PMID:25172293 |
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NCBI chr 3:156,874,805...156,899,601
Ensembl chr 3:156,886,454...156,899,436
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G |
Lpl |
lipoprotein lipase |
increases expression |
EXP |
Triiodothyronine results in increased expression of LPL mRNA |
CTD |
PMID:15953391 |
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NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496
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G |
Lss |
lanosterol synthase |
increases expression |
EXP |
Triiodothyronine results in increased expression of LSS mRNA |
CTD |
PMID:15953391 |
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NCBI chr20:12,844,522...12,870,474
Ensembl chr20:12,842,884...12,870,497
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G |
Ltb4r |
leukotriene B4 receptor |
multiple interactions |
ISO |
[Triiodothyronine co-treated with Tetrachlorodibenzodioxin] results in decreased expression of LTB4R mRNA |
CTD |
PMID:14761676 |
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NCBI chr15:34,449,299...34,453,352
Ensembl chr15:34,452,116...34,453,171
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G |
Lyrm9 |
LYR motif containing 9 |
decreases expression |
ISO |
Triiodothyronine results in decreased expression of LYRM9 mRNA |
CTD |
PMID:23397585 |
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NCBI chr10:66,099,478...66,113,559
Ensembl chr10:66,099,531...66,113,559
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G |
Map1lc3b |
microtubule-associated protein 1 light chain 3 beta |
increases lipidation increases expression multiple interactions |
ISO |
Triiodothyronine results in increased lipidation of MAP1LC3B protein Triiodothyronine results in increased expression of MAP1LC3B mRNA bafilomycin A1 promotes the reaction [Triiodothyronine results in increased lipidation of MAP1LC3B protein]; Triiodothyronine promotes the reaction [bafilomycin A1 results in increased lipidation of MAP1LC3B protein] |
CTD |
PMID:30209975 |
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NCBI chr19:53,635,449...53,643,970
Ensembl chr19:53,629,779...53,646,058
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions increases expression |
ISO EXP |
tetraiodothyroacetic acid inhibits the reaction [Triiodothyronine results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Triiodothyronine results in increased phosphorylation of and results in increased activity of MAPK1 protein Triiodothyronine results in increased expression of MAPK1 mRNA Triiodothyronine promotes the reaction [FGF2 protein results in increased phosphorylation of and results in increased activity of MAPK1 protein] Triiodothyronine inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]; Triiodothyronine promotes the reaction [FGF18 protein results in increased phosphorylation of MAPK1 protein]; Triiodothyronine promotes the reaction [FGF2 protein results in increased phosphorylation of MAPK1 protein]; Triiodothyronine promotes the reaction [FGF9 protein results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [Triiodothyronine results in increased expression of MAPK1 mRNA] |
CTD |
PMID:12805413 PMID:16150908 PMID:17174366 PMID:28315333 |
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NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions increases expression |
ISO EXP |
tetraiodothyroacetic acid inhibits the reaction [Triiodothyronine results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Triiodothyronine results in increased phosphorylation of and results in increased activity of MAPK3 protein Triiodothyronine results in increased expression of MAPK3 mRNA Triiodothyronine promotes the reaction [FGF2 protein results in increased phosphorylation of and results in increased activity of MAPK3 protein] Triiodothyronine inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]; Triiodothyronine promotes the reaction [FGF18 protein results in increased phosphorylation of MAPK3 protein]; Triiodothyronine promotes the reaction [FGF2 protein results in increased phosphorylation of MAPK3 protein]; Triiodothyronine promotes the reaction [FGF9 protein results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [Triiodothyronine results in increased expression of MAPK3 mRNA] |
CTD |
PMID:12805413 PMID:16150908 PMID:17174366 PMID:28315333 |
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NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
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G |
Mbp |
myelin basic protein |
increases expression |
ISO |
Triiodothyronine results in increased expression of MBP protein alternative form |
CTD |
PMID:15345905 |
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NCBI chr18:79,326,738...79,437,310
Ensembl chr18:79,326,738...79,437,310
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G |
Me1 |
malic enzyme 1 |
increases expression |
EXP |
Triiodothyronine results in increased expression of ME1 mRNA |
CTD |
PMID:15953391 PMID:29357290 |
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NCBI chr 8:94,256,830...94,368,834
Ensembl chr 8:94,256,839...94,368,834
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G |
Meioc |
meiosis specific with coiled-coil domain |
decreases expression |
ISO |
Triiodothyronine results in decreased expression of MEIOC mRNA |
CTD |
PMID:23397585 |
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NCBI chr10:90,622,954...90,641,883
Ensembl chr10:90,622,992...90,642,151
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G |
Mfsd2a |
major facilitator superfamily domain containing 2A |
increases expression |
ISO |
Triiodothyronine results in increased expression of MFSD2A mRNA |
CTD |
PMID:25172293 |
|
NCBI chr 5:140,642,865...140,657,759
Ensembl chr 5:140,642,885...140,657,745
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G |
Mier3 |
MIER family member 3 |
decreases expression |
ISO |
Triiodothyronine results in decreased expression of MIER3 mRNA |
CTD |
PMID:23397585 |
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NCBI chr 2:43,266,301...43,295,175
Ensembl chr 2:43,266,739...43,294,889
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G |
Mki67 |
marker of proliferation Ki-67 |
increases expression multiple interactions |
ISO |
Triiodothyronine results in increased expression of MKI67 mRNA U 0126 inhibits the reaction [Triiodothyronine results in increased expression of MKI67 mRNA] |
CTD |
PMID:28315333 |
|
NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454
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G |
Mmd2 |
monocyte to macrophage differentiation-associated 2 |
increases expression |
EXP |
Triiodothyronine results in increased expression of MMD2 mRNA |
CTD |
PMID:29357290 |
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NCBI chr12:14,021,724...14,078,121
Ensembl chr12:14,021,727...14,078,134
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G |
Mmp11 |
matrix metallopeptidase 11 |
multiple interactions increases expression |
ISO |
(4-(4-hydroxy-3-isopropyl-5-(4-nitrophenylethynyl)benzyl)-3,5-dimethylphenoxy)acetic acid inhibits the reaction [Triiodothyronine results in increased expression of MMP11 mRNA]; SJ 000311413 inhibits the reaction [Triiodothyronine results in increased expression of MMP11 mRNA] |
CTD |
PMID:21815645 |
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NCBI chr20:13,670,051...13,678,834
Ensembl chr20:13,670,066...13,678,089
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G |
Mmp2 |
matrix metallopeptidase 2 |
multiple interactions |
EXP |
Triiodothyronine inhibits the reaction [TGFB1 protein results in increased secretion of MMP2 protein] |
CTD |
PMID:18031379 |
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NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
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G |
Mpo |
myeloperoxidase |
multiple interactions |
EXP |
[Triiodothyronine co-treated with Hexachlorocyclohexane] results in increased activity of MPO protein |
CTD |
PMID:7503757 |
|
NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
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G |
Mtor |
mechanistic target of rapamycin kinase |
decreases phosphorylation |
ISO |
Triiodothyronine results in decreased phosphorylation of MTOR protein |
CTD |
PMID:30209975 |
|
NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
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G |
Myh6 |
myosin heavy chain 6 |
multiple interactions increases expression |
EXP |
S100A6 protein inhibits the reaction [Triiodothyronine results in increased expression of MYH6 mRNA]; Triiodothyronine inhibits the reaction [Phenylephrine results in decreased expression of MYH6 mRNA] |
CTD |
PMID:11577024 PMID:15578571 PMID:15652358 |
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NCBI chr15:33,605,653...33,629,730
Ensembl chr15:33,605,654...33,629,699
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G |
Myh7 |
myosin heavy chain 7 |
multiple interactions decreases expression |
EXP |
Triiodothyronine inhibits the reaction [Phenylephrine results in increased expression of MYH7 mRNA] Triiodothyronine results in decreased expression of MYH7 mRNA |
CTD |
PMID:11577024 PMID:15578571 |
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NCBI chr15:33,605,769...33,657,761
Ensembl chr15:33,634,422...33,656,089
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G |
Naglt1 |
Na+ dependent glucose transporter 1 |
increases expression |
EXP |
Triiodothyronine results in increased expression of NAGLT1 mRNA |
CTD |
PMID:15953391 |
|
NCBI chr20:45,095,232...45,107,532
Ensembl chr20:45,094,791...45,107,555
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G |
Ncapg2 |
non-SMC condensin II complex, subunit G2 |
decreases expression |
ISO |
Triiodothyronine results in decreased expression of NCAPG2 mRNA |
CTD |
PMID:23397585 |
|
NCBI chr 6:144,291,313...144,362,454
Ensembl chr 6:144,291,974...144,363,947
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G |
Ncoa1 |
nuclear receptor coactivator 1 |
multiple interactions |
ISO |
[Triiodothyronine co-treated with NCOA1 protein] results in increased activity of THRB protein; bisphenol A inhibits the reaction [[Triiodothyronine co-treated with NCOA1 protein] results in increased activity of THRB protein] |
CTD |
PMID:22227104 |
|
NCBI chr 6:28,677,563...28,931,844
Ensembl chr 6:28,677,540...28,931,843
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G |
Ncoa2 |
nuclear receptor coactivator 2 |
multiple interactions |
ISO |
Triiodothyronine promotes the reaction [NCOA2 protein binds to THRA protein]; Triiodothyronine promotes the reaction [NCOA2 protein binds to THRB protein]; Triiodothyronine promotes the reaction [THRA protein binds to NCOA2 protein]; Triiodothyronine promotes the reaction [THRB protein binds to NCOA2 protein] |
CTD |
PMID:29146198 PMID:31566444 |
|
NCBI chr 5:5,466,544...5,696,540
Ensembl chr 5:5,616,483...5,694,598
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G |
Ncor1 |
nuclear receptor co-repressor 1 |
multiple interactions |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Triiodothyronine inhibits the reaction [THRB protein binds to NCOR1 protein]]; AG 1879 inhibits the reaction [Triiodothyronine inhibits the reaction [THRB protein binds to NCOR1 protein]]; bisphenol A inhibits the reaction [Triiodothyronine inhibits the reaction [NCOR1 protein binds to and results in decreased activity of THRB protein]]; bisphenol A inhibits the reaction [Triiodothyronine inhibits the reaction [THRB protein binds to NCOR1 protein]]; ITGB3 inhibits the reaction [bisphenol A inhibits the reaction [Triiodothyronine inhibits the reaction [NCOR1 protein binds to and results in decreased activity of THRB protein]]]; SRC inhibits the reaction [bisphenol A inhibits the reaction [Triiodothyronine inhibits the reaction [NCOR1 protein binds to and results in decreased activity of THRB protein]]]; tetraiodothyroacetic acid inhibits the reaction [Triiodothyronine inhibits the reaction [THRB protein binds to NCOR1 protein]]; Triiodothyronine inhibits the reaction [NCOR1 protein binds to and results in decreased activity of THRB protein]; Triiodothyronine inhibits the reaction [THRB protein binds to NCOR1 protein] |
CTD |
PMID:22227104 |
|
NCBI chr10:48,629,121...48,772,890
Ensembl chr10:48,629,121...48,772,890
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G |
Ncor2 |
nuclear receptor co-repressor 2 |
multiple interactions |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Triiodothyronine inhibits the reaction [THRB protein binds to NCOR2 protein]]; AG 1879 inhibits the reaction [Triiodothyronine inhibits the reaction [THRB protein binds to NCOR2 protein]]; bisphenol A inhibits the reaction [Triiodothyronine inhibits the reaction [THRB protein binds to NCOR2 protein]]; ITGB3 inhibits the reaction [bisphenol A inhibits the reaction [Triiodothyronine inhibits the reaction [NCOR2 protein binds to and results in decreased activity of THRB protein]]]; SRC inhibits the reaction [bisphenol A inhibits the reaction [Triiodothyronine inhibits the reaction [NCOR2 protein binds to and results in decreased activity of THRB protein]]]; tetraiodothyroacetic acid inhibits the reaction [Triiodothyronine inhibits the reaction [THRB protein binds to NCOR2 protein]]; Triiodothyronine inhibits the reaction [THRB protein binds to NCOR2 protein] |
CTD |
PMID:22227104 |
|
NCBI chr12:36,871,917...37,033,701
Ensembl chr12:36,871,999...37,033,701
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G |
Ndufa5 |
NADH:ubiquinone oxidoreductase subunit A5 |
increases expression |
EXP |
Triiodothyronine results in increased expression of NDUFA5 mRNA |
CTD |
PMID:15953391 |
|
NCBI chr 4:51,590,413...51,598,771
Ensembl chr 4:51,590,413...51,598,771
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G |
Nefl |
neurofilament light |
decreases expression |
ISO |
Triiodothyronine results in decreased expression of NEFL mRNA |
CTD |
PMID:25172293 |
|
NCBI chr15:44,799,378...44,803,251
Ensembl chr15:44,799,334...44,804,574
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G |
Nefm |
neurofilament medium |
decreases expression |
ISO |
Triiodothyronine results in decreased expression of NEFM mRNA |
CTD |
PMID:25172293 |
|
NCBI chr15:44,855,307...44,860,604
Ensembl chr15:44,855,310...44,860,604
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G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
increases activity multiple interactions |
EXP |
Triiodothyronine results in increased activity of NFKB1 protein Hexachlorocyclohexane affects the reaction [Triiodothyronine results in increased activity of NFKB1 protein] |
CTD |
PMID:15019085 |
|
NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
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G |
Nnat |
neuronatin |
decreases expression |
EXP |
Triiodothyronine results in decreased expression of NNAT mRNA |
CTD |
PMID:29357290 |
|
NCBI chr 3:154,043,873...154,046,334
Ensembl chr 3:154,043,873...154,046,330
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G |
Npnt |
nephronectin |
increases expression |
ISO |
Triiodothyronine results in increased expression of NPNT mRNA |
CTD |
PMID:25172293 |
|
NCBI chr 2:238,001,767...238,068,886
Ensembl chr 2:238,002,990...238,068,694
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G |
Nr0b2 |
nuclear receptor subfamily 0, group B, member 2 |
increases expression |
EXP |
Triiodothyronine results in increased expression of NR0B2 mRNA |
CTD |
PMID:29357290 |
|
NCBI chr 5:151,776,004...151,779,319
Ensembl chr 5:151,776,004...151,779,319
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G |
Nr4a1 |
nuclear receptor subfamily 4, group A, member 1 |
multiple interactions |
ISO |
2,2',4,4'-tetrahydroxybenzophenone inhibits the reaction [Triiodothyronine inhibits the reaction [[NR4A1 co-treated with THRA] results in increased expression of HSD3B1 mRNA]]; 2,2',4,4'-tetrahydroxybenzophenone inhibits the reaction [Triiodothyronine inhibits the reaction [[NR4A1 co-treated with THRA] results in increased expression of STAR mRNA]]; 2,2',4,4'-tetrahydroxybenzophenone inhibits the reaction [Triiodothyronine promotes the reaction [[NR4A1 co-treated with THRA] results in increased expression of HSD3B1 mRNA]]; Triiodothyronine inhibits the reaction [[NR4A1 co-treated with THRA] results in increased expression of HSD3B1 mRNA]; Triiodothyronine inhibits the reaction [[NR4A1 co-treated with THRA] results in increased expression of STAR mRNA]; Triiodothyronine promotes the reaction [[NR4A1 co-treated with THRA] results in increased expression of HSD3B1 mRNA] |
CTD |
PMID:21726595 |
|
NCBI chr 7:142,899,358...142,920,216
Ensembl chr 7:142,905,758...142,920,216
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G |
Nrgn |
neurogranin |
increases expression |
EXP |
Triiodothyronine results in increased expression of NRGN mRNA; Triiodothyronine results in increased expression of NRGN protein |
CTD |
PMID:15708448 |
|
NCBI chr 8:40,015,049...40,023,193
Ensembl chr 8:40,015,049...40,023,193
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G |
Nrp1 |
neuropilin 1 |
increases expression |
EXP |
Triiodothyronine results in increased expression of NRP1 mRNA |
CTD |
PMID:15953391 |
|
NCBI chr19:61,332,351...61,486,166
Ensembl chr19:61,332,351...61,485,858
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G |
Nsdhl |
NAD(P) dependent steroid dehydrogenase-like |
increases expression |
EXP |
Triiodothyronine results in increased expression of NSDHL mRNA |
CTD |
PMID:15953391 |
|
NCBI chr X:152,933,118...152,964,399
Ensembl chr X:152,933,069...152,964,390
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G |
Nsmf |
NMDA receptor synaptonuclear signaling and neuronal migration factor |
increases expression |
EXP |
Triiodothyronine results in increased expression of NSMF mRNA |
CTD |
PMID:15953391 |
|
NCBI chr 3:2,262,173...2,270,996
Ensembl chr 3:2,262,253...2,270,995
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G |
Nt5e |
5' nucleotidase, ecto |
increases expression increases activity |
EXP |
Triiodothyronine results in increased expression of NT5E mRNA Triiodothyronine results in increased activity of NT5E protein |
CTD |
PMID:15543949 |
|
NCBI chr 8:95,969,002...96,012,733
Ensembl chr 8:95,968,652...96,012,696
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G |
Nudt7 |
nudix hydrolase 7 |
increases expression |
EXP |
Triiodothyronine results in increased expression of NUDT7 mRNA |
CTD |
PMID:15953391 |
|
NCBI chr19:46,455,745...46,470,070
Ensembl chr19:46,455,761...46,482,050
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G |
Nup214 |
nucleoporin 214 |
multiple interactions |
ISO |
[Triiodothyronine co-treated with Tetrachlorodibenzodioxin] results in decreased expression of NUP214 mRNA |
CTD |
PMID:14761676 |
|
NCBI chr 3:9,227,869...9,236,878 NCBI chr 3:10,993,584...11,070,638
Ensembl chr 3:9,227,823...9,236,736 Ensembl chr 3:9,227,823...9,236,736
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G |
Ocln |
occludin |
increases expression |
EXP |
Triiodothyronine results in increased expression of OCLN mRNA |
CTD |
PMID:15953391 |
|
NCBI chr 2:30,527,327...30,577,218
Ensembl chr 2:30,527,715...30,577,218
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G |
Olr59 |
olfactory receptor 59 |
increases expression |
EXP |
Triiodothyronine results in increased expression of OLR59 mRNA |
CTD |
PMID:28299817 |
|
NCBI chr 1:167,906,030...167,940,688
Ensembl chr 1:167,906,061...167,911,961
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G |
Osgin1 |
oxidative stress induced growth inhibitor 1 |
increases expression |
ISO |
Triiodothyronine results in increased expression of OSGIN1 mRNA |
CTD |
PMID:25172293 |
|
NCBI chr19:52,056,808...52,085,491
Ensembl chr19:52,077,109...52,085,496
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G |
P4hb |
prolyl 4-hydroxylase subunit beta |
multiple interactions affects binding |
EXP |
4-OH-2',3,3',4',5'-pentachlorobiphenyl inhibits the reaction [Triiodothyronine binds to P4HB protein]; bisphenol A inhibits the reaction [Triiodothyronine binds to P4HB protein]; P4HB protein inhibits the reaction [Triiodothyronine results in increased expression of and results in increased secretion of GH protein]; P4HB protein inhibits the reaction [Triiodothyronine results in increased expression of GH mRNA]; P4HB protein inhibits the reaction [Triiodothyronine results in increased expression of GH1 mRNA]; P4HB protein inhibits the reaction [Triiodothyronine results in increased expression of GH1 protein]; Polychlorinated Biphenyls metabolite inhibits the reaction [Triiodothyronine binds to P4HB protein] |
CTD |
PMID:17928132 PMID:18515855 PMID:19374345 PMID:22201216 |
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NCBI chr10:109,736,459...109,748,070
Ensembl chr10:109,736,458...109,747,987
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G |
Padi4 |
peptidyl arginine deiminase 4 |
increases expression |
EXP |
Triiodothyronine results in increased expression of PADI4 mRNA |
CTD |
PMID:15953391 |
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NCBI chr 5:159,260,675...159,293,906
Ensembl chr 5:159,260,675...159,293,673
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G |
Parp4 |
poly (ADP-ribose) polymerase family, member 4 |
decreases expression |
ISO |
Triiodothyronine results in decreased expression of PARP4 mRNA |
CTD |
PMID:23397585 |
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NCBI chr15:36,809,362...36,911,167
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G |
Pck1 |
phosphoenolpyruvate carboxykinase 1 |
multiple interactions increases expression |
EXP ISO |
SIRT1 protein affects the reaction [Triiodothyronine results in increased expression of PCK1 mRNA] (4-(4-hydroxy-3-isopropyl-5-(4-nitrophenylethynyl)benzyl)-3,5-dimethylphenoxy)acetic acid inhibits the reaction [Triiodothyronine results in increased expression of PCK1 mRNA]; SJ 000311413 inhibits the reaction [Triiodothyronine results in increased expression of PCK1 mRNA] |
CTD |
PMID:21815645 PMID:23209300 PMID:30209975 |
|
NCBI chr 3:171,213,936...171,219,885
Ensembl chr 3:171,213,936...171,219,871
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G |
Pcna |
proliferating cell nuclear antigen |
increases expression multiple interactions affects binding |
ISO |
Triiodothyronine results in increased expression of PCNA protein THRB protein promotes the reaction [Triiodothyronine results in increased expression of PCNA protein] Triiodothyronine analog inhibits the reaction [CDKN1A protein binds to PCNA protein]; Triiodothyronine analog inhibits the reaction [POLD3 protein binds to PCNA protein]; Triiodothyronine inhibits the reaction [CDKN1A protein binds to PCNA protein] Triiodothyronine analog binds to PCNA protein; Triiodothyronine binds to PCNA protein |
CTD |
PMID:17174366 PMID:20638743 PMID:22383522 |
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NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
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G |
Pcsk1 |
proprotein convertase subtilisin/kexin type 1 |
decreases expression |
ISO |
Triiodothyronine results in decreased expression of PCSK1 mRNA |
CTD |
PMID:15291740 |
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NCBI chr 2:91,450,162...91,497,091
Ensembl chr 2:91,450,162...91,497,091
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G |
Pcsk2 |
proprotein convertase subtilisin/kexin type 2 |
decreases expression |
ISO |
Triiodothyronine results in decreased expression of PCSK2 mRNA |
CTD |
PMID:15585599 |
|
NCBI chr 3:137,618,891...137,923,385
Ensembl chr 3:137,618,898...137,925,605
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G |
Pdk4 |
pyruvate dehydrogenase kinase 4 |
multiple interactions increases expression |
ISO EXP |
resveratrol promotes the reaction [Triiodothyronine results in increased expression of PDK4 mRNA] resveratrol promotes the reaction [Triiodothyronine results in increased expression of PDK4 mRNA]; SIRT1 protein affects the reaction [Triiodothyronine results in increased expression of PDK4 mRNA] |
CTD |
PMID:23209300 |
|
NCBI chr 4:30,546,772...30,556,774
Ensembl chr 4:30,546,664...30,556,814
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G |
Pdp2 |
pyruvate dehydrogenase phosphatase catalytic subunit 2 |
increases expression |
EXP |
Triiodothyronine results in increased expression of PDP2 mRNA |
CTD |
PMID:29357290 |
|
NCBI chr19:597,427...601,556
Ensembl chr19:597,427...601,469
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G |
Peg10 |
paternally expressed 10 |
increases expression |
ISO |
Triiodothyronine results in increased expression of PEG10 mRNA |
CTD |
PMID:23397585 |
|
NCBI chr 4:29,795,524...29,804,517
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G |
Pex5 |
peroxisomal biogenesis factor 5 |
increases expression |
ISO |
Triiodothyronine results in increased expression of PEX5 mRNA |
CTD |
PMID:23397585 |
|
NCBI chr 4:156,983,914...157,009,675
Ensembl chr 4:156,983,915...157,009,674 Ensembl chr 4:156,983,915...157,009,674
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G |
Pfkp |
phosphofructokinase, platelet |
increases expression |
ISO |
Triiodothyronine results in increased expression of PFKP mRNA |
CTD |
PMID:15507505 |
|
NCBI chr17:68,510,765...68,574,387
Ensembl chr17:68,511,064...68,559,471
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G |
Phospho1 |
phosphoethanolamine/phosphocholine phosphatase 1 |
increases expression |
ISO |
Triiodothyronine results in increased expression of PHOSPHO1 mRNA |
CTD |
PMID:25172293 |
|
NCBI chr10:83,635,557...83,643,862
Ensembl chr10:83,636,518...83,643,859
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G |
Pik3cd |
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta |
increases expression |
ISO |
Triiodothyronine results in increased expression of PIK3CD mRNA |
CTD |
PMID:25172293 |
|
NCBI chr 5:166,602,053...166,628,028
Ensembl chr 5:166,602,053...166,628,028
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G |
Pla2g6 |
phospholipase A2 group VI |
increases expression |
EXP |
Triiodothyronine results in increased expression of PLA2G6 mRNA |
CTD |
PMID:15953391 |
|
NCBI chr 7:120,519,479...120,559,716
Ensembl chr 7:120,519,467...120,559,347
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G |
Pld5 |
phospholipase D family, member 5 |
increases expression |
ISO |
Triiodothyronine results in increased expression of PLD5 mRNA |
CTD |
PMID:23397585 |
|
NCBI chr13:94,025,696...94,355,219
Ensembl chr13:94,025,369...94,355,219
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G |
Plin2 |
perilipin 2 |
increases expression |
EXP |
Triiodothyronine results in increased expression of PLIN2 mRNA |
CTD |
PMID:15953391 |
|
NCBI chr 5:104,984,413...105,010,863
Ensembl chr 5:104,984,414...105,010,857
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G |
Plin3 |
perilipin 3 |
multiple interactions |
ISO |
[THRA protein co-treated with Triiodothyronine] promotes the reaction [ANGPTL8 protein binds to PLIN3 protein] |
CTD |
PMID:24262987 |
|
NCBI chr 9:10,769,739...10,781,659
Ensembl chr 9:10,773,901...10,781,109
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G |
Plxnc1 |
plexin C1 |
increases expression |
ISO |
Triiodothyronine results in increased expression of PLXNC1 mRNA |
CTD |
PMID:23397585 |
|
NCBI chr 7:35,848,083...36,000,969
Ensembl chr 7:35,850,398...36,000,906
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G |
Pmp22 |
peripheral myelin protein 22 |
increases expression |
ISO |
Triiodothyronine results in increased expression of PMP22 mRNA |
CTD |
PMID:29901742 |
|
NCBI chr10:49,538,588...49,568,583
Ensembl chr10:49,538,588...49,568,583
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G |
Pnpla2 |
patatin-like phospholipase domain containing 2 |
increases expression decreases phosphorylation |
ISO |
Triiodothyronine results in increased expression of PNPLA2 mRNA Triiodothyronine results in decreased phosphorylation of PNPLA2 protein |
CTD |
PMID:30209975 |
|
NCBI chr 1:214,434,638...214,439,720
Ensembl chr 1:214,434,626...214,439,720 Ensembl chr 1:214,434,626...214,439,720
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G |
Podxl |
podocalyxin-like |
increases expression |
EXP |
Triiodothyronine results in increased expression of PODXL mRNA |
CTD |
PMID:15953391 |
|
NCBI chr 4:58,829,049...58,893,353
Ensembl chr 4:58,829,060...58,893,170
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G |
Pold3 |
DNA polymerase delta 3, accessory subunit |
multiple interactions |
ISO |
Triiodothyronine analog inhibits the reaction [POLD3 protein binds to PCNA protein] |
CTD |
PMID:22383522 |
|
NCBI chr 1:165,085,142...165,122,385
Ensembl chr 1:165,083,622...165,123,455
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G |
Polg |
DNA polymerase gamma, catalytic subunit |
multiple interactions |
ISO |
[Triiodothyronine co-treated with Tetrachlorodibenzodioxin] results in decreased expression of POLG mRNA |
CTD |
PMID:14761676 |
|
NCBI chr 1:141,172,117...141,188,893
Ensembl chr 1:141,172,531...141,188,031
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G |
Pomt1 |
protein-O-mannosyltransferase 1 |
increases expression |
EXP |
Triiodothyronine results in increased expression of POMT1 mRNA |
CTD |
PMID:15953391 |
|
NCBI chr 3:11,253,424...11,271,873
Ensembl chr 3:11,254,026...11,271,872
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G |
Ppara |
peroxisome proliferator activated receptor alpha |
multiple interactions |
EXP |
[GW 7647 results in increased activity of PPARA protein] promotes the reaction [Phenobarbital results in increased degradation of Triiodothyronine]; [pirinixic acid results in increased activity of PPARA protein] promotes the reaction [Phenobarbital results in increased degradation of Triiodothyronine]; [Triiodothyronine co-treated with Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA |
CTD |
PMID:19631232 PMID:25048947 |
|
NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
multiple interactions |
EXP |
Triiodothyronine inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of PPARG mRNA] |
CTD |
PMID:25048947 |
|
NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
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G |
Ppargc1a |
PPARG coactivator 1 alpha |
increases expression |
EXP ISO |
Triiodothyronine results in increased expression of PPARGC1A mRNA |
CTD |
PMID:23209300 PMID:30209975 |
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NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
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G |
Prdm16 |
PR/SET domain 16 |
increases expression |
ISO |
Triiodothyronine results in increased expression of PRDM16 mRNA |
CTD |
PMID:30209975 |
|
NCBI chr 5:171,662,277...171,711,561
Ensembl chr 5:171,662,277...171,710,316
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G |
Prelp |
proline and arginine rich end leucine rich repeat protein |
decreases expression |
ISO |
Triiodothyronine results in decreased expression of PRELP mRNA |
CTD |
PMID:25172293 |
|
NCBI chr13:50,749,526...50,773,934
Ensembl chr13:50,749,514...50,761,355
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G |
Prickle2 |
prickle planar cell polarity protein 2 |
decreases expression |
ISO |
Triiodothyronine results in decreased expression of PRICKLE2 mRNA |
CTD |
PMID:25172293 |
|
NCBI chr 4:124,238,167...124,584,176
Ensembl chr 4:124,238,167...124,338,176
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G |
Prl |
prolactin |
decreases expression increases secretion multiple interactions |
EXP |
Triiodothyronine results in decreased expression of PRL mRNA; Triiodothyronine results in decreased expression of PRL protein Triiodothyronine results in increased secretion of PRL protein bisphenol A inhibits the reaction [Triiodothyronine results in increased secretion of PRL protein]; Chlorodiphenyl (54% Chlorine) promotes the reaction [Triiodothyronine results in increased secretion of PRL protein] |
CTD |
PMID:3734668 PMID:17615682 |
|
NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299
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G |
Prokr1 |
prokineticin receptor 1 |
increases expression |
ISO |
Triiodothyronine results in increased expression of PROKR1 mRNA |
CTD |
PMID:25172293 |
|
NCBI chr 4:119,375,790...119,386,551
Ensembl chr 4:119,375,778...119,386,590
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G |
Psca |
prostate stem cell antigen |
multiple interactions increases expression |
ISO |
4-OH-2',3,3',4',5'-pentachlorobiphenyl inhibits the reaction [Triiodothyronine results in increased expression of PSCA mRNA]; Polychlorinated Biphenyls inhibits the reaction [Triiodothyronine results in increased expression of PSCA mRNA]; Tetrachlorodibenzodioxin promotes the reaction [Triiodothyronine results in increased expression of PSCA mRNA]; Tetrachlorodibenzodioxin promotes the reaction [Triiodothyronine results in increased expression of PSCA protein] Triiodothyronine results in increased expression of PSCA mRNA; Triiodothyronine results in increased expression of PSCA protein |
CTD |
PMID:14761676 |
|
NCBI chr 7:116,090,189...116,091,955
Ensembl chr 7:116,090,189...116,091,955
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
increases expression |
ISO |
Triiodothyronine results in increased expression of PTGS2 mRNA |
CTD |
PMID:32816093 |
|
NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
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G |
Rab23 |
RAB23, member RAS oncogene family |
decreases expression |
ISO |
Triiodothyronine results in decreased expression of RAB23 mRNA |
CTD |
PMID:23397585 |
|
NCBI chr 9:38,469,784...38,496,185
Ensembl chr 9:38,470,298...38,495,176
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G |
Rab3b |
RAB3B, member RAS oncogene family |
increases expression |
ISO |
Triiodothyronine results in increased expression of RAB3B mRNA |
CTD |
PMID:15507505 |
|
NCBI chr 5:128,501,789...128,568,170
Ensembl chr 5:128,501,847...128,568,188
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G |
Rarb |
retinoic acid receptor, beta |
increases expression |
EXP |
Triiodothyronine results in increased expression of RARB mRNA |
CTD |
PMID:15708448 |
|
NCBI chr15:9,915,223...10,262,599
Ensembl chr15:10,120,206...10,262,599
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions increases activity |
EXP |
Hexachlorocyclohexane affects the reaction [Triiodothyronine results in increased activity of RELA protein] |
CTD |
PMID:15019085 |
|
NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
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G |
Retsat |
retinol saturase |
increases expression |
EXP |
Triiodothyronine results in increased expression of RETSAT mRNA |
CTD |
PMID:15953391 |
|
NCBI chr 4:100,465,365...100,474,128
Ensembl chr 4:100,465,170...100,474,301
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G |
RGD1306063 |
similar to HT021 |
increases expression |
EXP |
Triiodothyronine results in increased expression of RGD1306063 mRNA |
CTD |
PMID:15953391 |
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NCBI chr15:12,869,217...12,889,144
Ensembl chr15:12,872,408...12,889,108
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RGD1307603 |
similar to hypothetical protein MGC37914 |
decreases expression |
EXP |
Triiodothyronine results in decreased expression of RGD1307603 mRNA |
CTD |
PMID:29357290 |
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NCBI chr 1:219,309,593...219,312,240
Ensembl chr 1:219,309,592...219,312,240
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G |
RGD1564801 |
similar to hepatic multiple inositol polyphosphate phosphatase |
increases expression |
EXP |
Triiodothyronine results in increased expression of RGD1564801 mRNA |
CTD |
PMID:15953391 |
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NCBI chr 1:75,151,956...75,154,325
Ensembl chr 1:75,152,883...75,154,325
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G |
RGD1564865 |
similar to 20-alpha-hydroxysteroid dehydrogenase |
increases expression |
ISO |
Triiodothyronine results in increased expression of AKR1C1 mRNA |
CTD |
PMID:15507505 |
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NCBI chr17:69,468,427...69,497,132
Ensembl chr17:69,468,427...69,497,132
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G |
Rhov |
ras homolog family member V |
increases expression |
ISO |
Triiodothyronine results in increased expression of RHOV mRNA |
CTD |
PMID:23397585 |
|
NCBI chr 3:111,078,642...111,087,347
Ensembl chr 3:111,078,619...111,087,347
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G |
Rpa2 |
replication protein A2 |
increases phosphorylation |
ISO |
Triiodothyronine analog results in increased phosphorylation of RPA2 protein |
CTD |
PMID:22383522 |
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NCBI chr 5:150,957,041...150,967,597
Ensembl chr 5:150,957,001...150,968,269
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G |
Rps6kb1 |
ribosomal protein S6 kinase B1 |
multiple interactions decreases phosphorylation |
ISO |
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [Triiodothyronine results in decreased phosphorylation of RPS6KB1 protein] |
CTD |
PMID:30209975 |
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NCBI chr10:73,824,200...73,865,503
Ensembl chr10:73,824,202...73,865,364
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G |
Rxrb |
retinoid X receptor beta |
increases expression |
EXP |
Triiodothyronine results in increased expression of RXRB mRNA |
CTD |
PMID:15708448 |
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NCBI chr20:3,822,673...3,829,138
Ensembl chr20:3,823,042...3,829,140
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G |
Rxrg |
retinoid X receptor gamma |
increases expression |
EXP |
Triiodothyronine results in increased expression of RXRG mRNA |
CTD |
PMID:15708448 |
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NCBI chr13:85,818,473...85,868,555
Ensembl chr13:85,818,427...85,868,552
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G |
S100a6 |
S100 calcium binding protein A6 |
multiple interactions |
EXP |
S100A6 protein inhibits the reaction [Triiodothyronine results in increased expression of MYH6 mRNA] |
CTD |
PMID:15652358 |
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NCBI chr 2:190,007,013...190,008,512
Ensembl chr 2:190,007,216...190,008,511
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G |
Sc5d |
sterol-C5-desaturase |
increases expression |
EXP |
Triiodothyronine results in increased expression of SC5D mRNA |
CTD |
PMID:15953391 |
|
NCBI chr 8:46,525,406...46,537,014
Ensembl chr 8:46,525,400...46,537,050
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G |
Scd |
stearoyl-CoA desaturase |
increases expression |
EXP |
Triiodothyronine results in increased expression of SCD1 mRNA |
CTD |
PMID:15953391 |
|
NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
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G |
Serpina6 |
serpin family A member 6 |
increases expression |
EXP |
Triiodothyronine results in increased expression of SERPINA6 mRNA |
CTD |
PMID:29357290 |
|
NCBI chr 6:127,523,948...127,534,178
Ensembl chr 6:127,523,906...127,534,247
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G |
Serpina7 |
serpin family A member 7 |
affects binding |
ISO |
Triiodothyronine binds to SERPINA7 protein |
CTD |
PMID:20804816 PMID:21517007 |
|
NCBI chr X:110,226,565...110,232,202
Ensembl chr X:110,226,572...110,232,179
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G |
Sigmar1 |
sigma non-opioid intracellular receptor 1 |
increases expression |
EXP |
Triiodothyronine results in increased expression of SIGMAR1 mRNA |
CTD |
PMID:15953391 |
|
NCBI chr 5:58,121,824...58,124,687
Ensembl chr 5:58,121,786...58,124,681
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G |
Sirt1 |
sirtuin 1 |
multiple interactions increases expression affects response to substance |
EXP |
SIRT1 protein affects the reaction [Triiodothyronine results in decreased activity of SREBF1 protein]; SIRT1 protein affects the reaction [Triiodothyronine results in decreased expression of SREBF1 mRNA]; SIRT1 protein affects the reaction [Triiodothyronine results in increased expression of CPT1A mRNA]; SIRT1 protein affects the reaction [Triiodothyronine results in increased expression of CPT1A protein]; SIRT1 protein affects the reaction [Triiodothyronine results in increased expression of PCK1 mRNA]; SIRT1 protein affects the reaction [Triiodothyronine results in increased expression of PDK4 mRNA] Triiodothyronine results in increased expression of SIRT1 mRNA SIRT1 protein affects the susceptibility to Triiodothyronine |
CTD |
PMID:23209300 |
|
NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
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G |
Slc10a2 |
solute carrier family 10 member 2 |
increases expression |
EXP |
Triiodothyronine results in increased expression of SLC10A2 mRNA |
CTD |
PMID:28299817 |
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NCBI chr16:90,324,420...90,350,254
Ensembl chr16:90,324,361...90,345,865
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G |
Slc15a1 |
solute carrier family 15 member 1 |
multiple interactions decreases expression |
ISO |
resveratrol inhibits the reaction [Triiodothyronine results in decreased expression of SLC15A1 mRNA]; resveratrol inhibits the reaction [Triiodothyronine results in decreased expression of SLC15A1 protein] Triiodothyronine results in decreased expression of SLC15A1 mRNA; Triiodothyronine results in decreased expression of SLC15A1 protein |
CTD |
PMID:26394120 |
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NCBI chr15:106,800,081...106,844,668
Ensembl chr15:106,800,081...106,844,426
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G |
Slc16a2 |
solute carrier family 16 member 2 |
multiple interactions increases uptake |
ISO |
bisphenol A inhibits the reaction [SLC16A2 protein results in increased uptake of Triiodothyronine]; bosutinib inhibits the reaction [SLC16A2 protein results in increased uptake of Triiodothyronine]; Dasatinib inhibits the reaction [SLC16A2 protein results in increased uptake of Triiodothyronine]; Desipramine inhibits the reaction [SLC16A2 protein results in increased uptake of Triiodothyronine]; Genistein inhibits the reaction [SLC16A2 protein results in increased uptake of Triiodothyronine]; Imatinib Mesylate inhibits the reaction [SLC16A2 protein results in increased uptake of Triiodothyronine]; Indocyanine Green inhibits the reaction [SLC16A2 protein results in increased uptake of Triiodothyronine]; Meclofenamic Acid inhibits the reaction [SLC16A2 protein results in increased uptake of Triiodothyronine]; Phloretin inhibits the reaction [SLC16A2 protein results in increased uptake of Triiodothyronine]; Sulfobromophthalein inhibits the reaction [SLC16A2 protein results in increased uptake of Triiodothyronine] |
CTD |
PMID:28119167 |
|
NCBI chr X:74,578,600...74,706,068
Ensembl chr X:74,577,131...74,706,214
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G |
Slc16a3 |
solute carrier family 16 member 3 |
increases expression |
ISO |
Triiodothyronine results in increased expression of SLC16A3 mRNA |
CTD |
PMID:15507505 |
|
NCBI chr10:110,138,519...110,148,360
Ensembl chr10:110,138,586...110,148,358
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G |
Slc16a6 |
solute carrier family 16, member 6 |
increases expression multiple interactions |
ISO |
Triiodothyronine results in increased expression of SLC16A6 mRNA (4-(4-hydroxy-3-isopropyl-5-(4-nitrophenylethynyl)benzyl)-3,5-dimethylphenoxy)acetic acid inhibits the reaction [Triiodothyronine results in increased expression of SLC16A6 mRNA] |
CTD |
PMID:21815645 |
|
NCBI chr10:97,733,701...97,758,723
Ensembl chr10:97,735,548...97,756,521
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G |
Slc1a2 |
solute carrier family 1 member 2 |
increases expression |
ISO |
Triiodothyronine results in increased expression of SLC1A2 mRNA |
CTD |
PMID:25172293 |
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NCBI chr 3:92,518,679...92,665,731
Ensembl chr 3:92,640,752...92,665,644
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G |
Slc25a25 |
solute carrier family 25 member 25 |
increases expression |
EXP |
Triiodothyronine results in increased expression of SLC25A25 mRNA |
CTD |
PMID:29357290 |
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NCBI chr 3:11,442,396...11,476,186
Ensembl chr 3:11,442,397...11,452,529
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G |
Slc2a1 |
solute carrier family 2 member 1 |
increases expression |
ISO |
Triiodothyronine results in increased expression of SLC2A1 mRNA |
CTD |
PMID:15507505 |
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NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897
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G |
Slc2a4 |
solute carrier family 2 member 4 |
multiple interactions |
ISO |
[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein co-treated with Indomethacin co-treated with rosiglitazone co-treated with Triiodothyronine] results in increased expression of SLC2A4 mRNA; [Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein co-treated with Indomethacin co-treated with rosiglitazone co-treated with Triiodothyronine] results in increased expression of SLC2A4 protein |
CTD |
PMID:27605626 |
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NCBI chr10:56,552,921...56,558,562
Ensembl chr10:56,552,983...56,558,487
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G |
Slc2a5 |
solute carrier family 2 member 5 |
multiple interactions |
EXP |
[Triiodothyronine co-treated with Fructose] results in increased expression of SLC2A5 mRNA |
CTD |
PMID:17485832 |
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NCBI chr 5:167,142,182...167,174,203
Ensembl chr 5:167,141,875...167,174,310
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G |
Slc38a2 |
solute carrier family 38, member 2 |
increases expression |
EXP |
Triiodothyronine results in increased expression of SLC38A2 mRNA |
CTD |
PMID:29357290 |
|
NCBI chr 7:138,088,654...138,100,869
Ensembl chr 7:138,088,649...138,100,841
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G |
Slc43a2 |
solute carrier family 43 member 2 |
increases expression |
ISO |
Triiodothyronine results in increased expression of SLC43A2 mRNA |
CTD |
PMID:25172293 |
|
NCBI chr10:63,676,317...63,719,283
Ensembl chr10:63,677,396...63,719,283
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G |
Slc51b |
solute carrier family 51 subunit beta |
increases expression multiple interactions |
ISO |
Triiodothyronine results in increased expression of SLC51B mRNA (4-(4-hydroxy-3-isopropyl-5-(4-nitrophenylethynyl)benzyl)-3,5-dimethylphenoxy)acetic acid inhibits the reaction [Triiodothyronine results in increased expression of SLC51B mRNA] |
CTD |
PMID:21815645 |
|
NCBI chr 8:70,930,196...70,938,559
Ensembl chr 8:70,930,347...70,932,986
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G |
Slc7a11 |
solute carrier family 7 member 11 |
increases expression |
ISO |
Triiodothyronine results in increased expression of SLC7A11 mRNA |
CTD |
PMID:32816093 |
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NCBI chr 2:139,453,774...139,528,479
Ensembl chr 2:139,453,774...139,528,162
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G |
Slpi |
secretory leukocyte peptidase inhibitor |
increases expression |
ISO |
Triiodothyronine results in increased expression of SLPI mRNA |
CTD |
PMID:32816093 |
|
NCBI chr 3:160,799,979...160,802,228
Ensembl chr 3:160,799,981...160,802,433
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G |
Sned1 |
sushi, nidogen and EGF-like domains 1 |
increases expression |
ISO |
Triiodothyronine results in increased expression of SNED1 mRNA |
CTD |
PMID:25172293 |
|
NCBI chr 9:100,380,487...100,439,125
Ensembl chr 9:100,380,515...100,437,056
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G |
Sod1 |
superoxide dismutase 1 |
multiple interactions decreases expression |
ISO |
Triiodothyronine inhibits the reaction [Paraquat results in decreased expression of SOD1 mRNA]; Triiodothyronine inhibits the reaction [THRA protein results in increased expression of SOD1 mRNA]; Triiodothyronine inhibits the reaction [THRB protein results in increased expression of SOD1 mRNA] Triiodothyronine results in decreased expression of SOD1 mRNA |
CTD |
PMID:16738222 |
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NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
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G |
Spen |
spen family transcriptional repressor |
increases expression |
ISO |
Triiodothyronine results in increased expression of SPEN mRNA |
CTD |
PMID:23397585 |
|
NCBI chr 5:160,015,573...160,070,915
Ensembl chr 5:160,015,454...160,070,965
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G |
Sptlc2 |
serine palmitoyltransferase, long chain base subunit 2 |
increases expression |
ISO |
Triiodothyronine results in increased expression of SPTLC2 mRNA |
CTD |
PMID:23397585 |
|
NCBI chr 6:111,334,408...111,417,960
Ensembl chr 6:111,339,136...111,417,954
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G |
Sqstm1 |
sequestosome 1 |
multiple interactions increases expression |
ISO |
[THRA protein co-treated with Triiodothyronine] results in decreased expression of SQSTM1 protein; Ammonium Chloride inhibits the reaction [[THRA protein co-treated with Triiodothyronine] results in decreased expression of SQSTM1 protein]; ANGPTL8 protein affects the reaction [[THRA protein co-treated with Triiodothyronine] results in decreased expression of SQSTM1 protein]; Chloroquine inhibits the reaction [[THRA protein co-treated with Triiodothyronine] results in decreased expression of SQSTM1 protein] Triiodothyronine results in increased expression of SQSTM1 mRNA |
CTD |
PMID:24262987 PMID:30209975 |
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NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
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G |
Src |
SRC proto-oncogene, non-receptor tyrosine kinase |
multiple interactions |
ISO |
SRC inhibits the reaction [bisphenol A inhibits the reaction [Triiodothyronine inhibits the reaction [NCOR1 protein binds to and results in decreased activity of THRB protein]]]; SRC inhibits the reaction [bisphenol A inhibits the reaction [Triiodothyronine inhibits the reaction [NCOR2 protein binds to and results in decreased activity of THRB protein]]] |
CTD |
PMID:22227104 |
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NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642
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G |
Srebf1 |
sterol regulatory element binding transcription factor 1 |
multiple interactions decreases expression decreases activity |
EXP |
SIRT1 protein affects the reaction [Triiodothyronine results in decreased activity of SREBF1 protein]; SIRT1 protein affects the reaction [Triiodothyronine results in decreased expression of SREBF1 mRNA] |
CTD |
PMID:23209300 |
|
NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009
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G |
Srsf3 |
serine and arginine rich splicing factor 3 |
decreases expression |
ISO |
Triiodothyronine results in decreased expression of SFRS3 mRNA |
CTD |
PMID:23397585 |
|
NCBI chr20:6,288,285...6,298,218
Ensembl chr20:6,288,267...6,298,213
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G |
Star |
steroidogenic acute regulatory protein |
multiple interactions |
ISO |
2,2',4,4'-tetrahydroxybenzophenone inhibits the reaction [Triiodothyronine inhibits the reaction [[NR4A1 co-treated with THRA] results in increased expression of STAR mRNA]]; Triiodothyronine inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of STAR mRNA]; Triiodothyronine inhibits the reaction [[NR4A1 co-treated with THRA] results in increased expression of STAR mRNA] |
CTD |
PMID:21726595 |
|
NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
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G |
Stard8 |
StAR-related lipid transfer domain containing 8 |
increases expression |
ISO |
Triiodothyronine results in increased expression of STARD8 mRNA |
CTD |
PMID:25172293 |
|
NCBI chr X:68,713,157...68,785,046
Ensembl chr X:68,713,123...68,785,052
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G |
Stat1 |
signal transducer and activator of transcription 1 |
multiple interactions |
ISO |
Triiodothyronine inhibits the reaction [FGF2 protein results in increased phosphorylation of STAT1 protein] |
CTD |
PMID:16150908 |
|
NCBI chr 9:54,287,540...54,327,958
Ensembl chr 9:54,287,541...54,484,533
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G |
Stat5a |
signal transducer and activator of transcription 5A |
increases expression |
ISO |
Triiodothyronine results in increased expression of STAT5A mRNA |
CTD |
PMID:25172293 |
|
NCBI chr10:88,764,732...88,789,060
Ensembl chr10:88,764,732...88,789,057
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G |
Stat5b |
signal transducer and activator of transcription 5B |
increases expression |
EXP |
Triiodothyronine results in increased expression of STAT5B mRNA |
CTD |
PMID:15953391 |
|
NCBI chr10:88,686,207...88,712,313
Ensembl chr10:88,686,207...88,754,829
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G |
Stk19 |
serine/threonine kinase 19 |
increases expression |
ISO |
Triiodothyronine results in increased expression of STK19 mRNA |
CTD |
PMID:23397585 |
|
NCBI chr20:4,317,440...4,517,128
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G |
Sult1a1 |
sulfotransferase family 1A member 1 |
increases sulfation multiple interactions affects sulfation |
ISO |
SULT1A1 protein results in increased sulfation of Triiodothyronine Triiodothyronine inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol] SULT1A1 gene polymorphism affects the sulfation of Triiodothyronine |
CTD |
PMID:11739018 PMID:15531517 |
|
NCBI chr 1:198,100,586...198,104,106
Ensembl chr 1:198,100,586...198,104,109
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G |
Sult2a1 |
sulfotransferase family 2A member 1 |
increases expression |
EXP |
Triiodothyronine results in increased expression of SULT2A1 mRNA |
CTD |
PMID:15953391 |
|
NCBI chr 1:76,558,721...76,614,315
Ensembl chr 1:76,252,329...76,780,230
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G |
Sult4a1 |
sulfotransferase family 4A, member 1 |
increases metabolic processing |
ISO |
SULT4A1 protein results in increased metabolism of Triiodothyronine |
CTD |
PMID:12039030 |
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NCBI chr 7:124,958,546...124,982,602
Ensembl chr 7:124,958,546...124,982,566
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G |
Taf5l |
TATA-box binding protein associated factor 5 like |
increases expression |
ISO |
Triiodothyronine results in increased expression of TAF5L mRNA |
CTD |
PMID:23397585 |
|
NCBI chr19:56,781,854...56,801,005
Ensembl chr19:56,781,859...56,799,445
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G |
Tcim |
transcriptional and immune response regulator |
multiple interactions increases expression |
ISO |
SJ 000311413 inhibits the reaction [Triiodothyronine results in increased expression of TCIM mRNA] |
CTD |
PMID:21815645 |
|
NCBI chr16:72,401,526...72,403,180
Ensembl chr16:72,401,887...72,403,179 Ensembl chr16:72,401,887...72,403,179
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G |
Tex264 |
testis expressed 264 |
increases expression |
EXP |
Triiodothyronine results in increased expression of TEX264 mRNA |
CTD |
PMID:29357290 |
|
NCBI chr 8:115,360,706...115,388,299
Ensembl chr 8:115,360,713...115,388,266
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G |
Tfeb |
transcription factor EB |
increases expression |
ISO |
Triiodothyronine results in increased expression of TFEB mRNA |
CTD |
PMID:25172293 |
|
NCBI chr 9:15,208,141...15,264,101
Ensembl chr 9:15,207,822...15,214,596
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G |
Tgfb1 |
transforming growth factor, beta 1 |
multiple interactions |
EXP |
Triiodothyronine inhibits the reaction [TGFB1 protein results in increased secretion of MMP2 protein]; Triiodothyronine promotes the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA] |
CTD |
PMID:18031379 |
|
NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
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G |
Tgoln2 |
trans-golgi network protein 2 |
decreases expression increases expression |
ISO |
Triiodothyronine results in decreased expression of TGOLN2 mRNA Triiodothyronine results in increased expression of TGOLN2 mRNA |
CTD |
PMID:23397585 |
|
NCBI chr 4:100,475,415...100,483,229
Ensembl chr 4:100,475,416...100,483,168
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G |
Thra |
thyroid hormone receptor alpha |
multiple interactions affects binding increases expression increases activity decreases expression |
ISO EXP |
(4-(4-hydroxy-3-isopropyl-5-(4-nitrophenylethynyl)benzyl)-3,5-dimethylphenoxy)acetic acid inhibits the reaction [Triiodothyronine results in increased expression of THRA mRNA]; 2,2',4,4'-tetrabromodiphenyl ether analog affects the reaction [Triiodothyronine binds to THRA protein]; [THRA protein co-treated with Triiodothyronine] promotes the reaction [ANGPTL8 protein binds to PLIN3 protein]; [THRA protein co-treated with Triiodothyronine] results in decreased expression of SQSTM1 protein; [THRA protein co-treated with Triiodothyronine] results in increased expression of ANGPTL8 mRNA; [THRA protein co-treated with Triiodothyronine] results in increased expression of ANGPTL8 protein; Ammonium Chloride inhibits the reaction [[THRA protein co-treated with Triiodothyronine] results in decreased expression of SQSTM1 protein]; ANGPTL8 protein affects the reaction [[THRA protein co-treated with Triiodothyronine] results in decreased expression of SQSTM1 protein]; bis(4-hydroxyphenyl)sulfone inhibits the reaction [Triiodothyronine binds to THRA protein]; bisphenol A inhibits the reaction [Triiodothyronine binds to THRA protein]; bisphenol A inhibits the reaction [Triiodothyronine results in increased activity of THRA protein]; bisphenol F inhibits the reaction [Triiodothyronine binds to THRA protein]; Chloroquine inhibits the reaction [[THRA protein co-treated with Triiodothyronine] results in decreased expression of SQSTM1 protein]; daidzein promotes the reaction [Triiodothyronine results in increased activity of THRA protein]; Genistein promotes the reaction [Triiodothyronine results in increased activity of THRA protein]; KB 130015 inhibits the reaction [Triiodothyronine binds to and results in increased activity of THRA protein]; pentabromodiphenyl ether analog inhibits the reaction [Triiodothyronine binds to THRA protein]; Polybrominated Biphenyls metabolite inhibits the reaction [Triiodothyronine results in increased activity of THRA protein]; tetrabromobisphenol A inhibits the reaction [Triiodothyronine binds to THRA protein]; tetrabromobisphenol A inhibits the reaction [Triiodothyronine results in increased activity of THRA protein]; tetrachlorodian inhibits the reaction [Triiodothyronine results in increased activity of THRA protein]; THRA protein affects the reaction [Triiodothyronine inhibits the reaction [Silicon Dioxide results in increased cleavage of CASP3 protein]]; THRA protein affects the reaction [Triiodothyronine inhibits the reaction [Silicon Dioxide results in increased expression of CASP3 mRNA]]; THRA protein affects the reaction [Triiodothyronine inhibits the reaction [Silicon Dioxide results in increased expression of CYCS mRNA]]; THRA protein affects the reaction [Triiodothyronine inhibits the reaction [Silicon Dioxide results in increased expression of IL1B mRNA]]; THRA protein affects the reaction [Triiodothyronine inhibits the reaction [Silicon Dioxide results in increased expression of IL6 mRNA]]; THRA protein affects the reaction [Triiodothyronine inhibits the reaction [Silicon Dioxide results in increased expression of TNF mRNA]]; THRA protein affects the reaction [Triiodothyronine inhibits the reaction [Silicon Dioxide results in increased secretion of IL1B protein]]; THRA protein affects the reaction [Triiodothyronine inhibits the reaction [Silicon Dioxide results in increased secretion of IL6 protein]]; THRA protein affects the reaction [Triiodothyronine inhibits the reaction [Silicon Dioxide results in increased secretion of TNF protein]]; tribromodiphenyl ether 28 analog affects the reaction [Triiodothyronine binds to THRA protein]; Triiodothyronine binds to and results in increased activity of THRA protein; Triiodothyronine inhibits the reaction [THRA protein results in increased expression of SOD1 mRNA]; Triiodothyronine promotes the reaction [NCOA2 protein binds to THRA protein]; Triiodothyronine promotes the reaction [THRA protein binds to NCOA2 protein] 2,2',4,4'-tetrahydroxybenzophenone inhibits the reaction [Triiodothyronine inhibits the reaction [[NR4A1 co-treated with THRA] results in increased expression of HSD3B1 mRNA]]; 2,2',4,4'-tetrahydroxybenzophenone inhibits the reaction [Triiodothyronine inhibits the reaction [[NR4A1 co-treated with THRA] results in increased expression of STAR mRNA]]; 2,2',4,4'-tetrahydroxybenzophenone inhibits the reaction [Triiodothyronine promotes the reaction [[NR4A1 co-treated with THRA] results in increased expression of HSD3B1 mRNA]]; 2,2',4,4'-tetrahydroxybenzophenone inhibits the reaction [Triiodothyronine results in increased expression of THRA mRNA]; CSK protein promotes the reaction [Tetrachlorodibenzodioxin promotes the reaction [Triiodothyronine binds to THRA protein]]; Tetrachlorodibenzodioxin promotes the reaction [Triiodothyronine binds to THRA protein]; Triiodothyronine inhibits the reaction [[NR4A1 co-treated with THRA] results in increased expression of HSD3B1 mRNA]; Triiodothyronine inhibits the reaction [[NR4A1 co-treated with THRA] results in increased expression of STAR mRNA]; Triiodothyronine promotes the reaction [[NR4A1 co-treated with THRA] results in increased expression of HSD3B1 mRNA] [bisphenol A co-treated with Estradiol co-treated with Triiodothyronine] results in increased expression of THRA mRNA; [bisphenol A co-treated with Triiodothyronine] results in increased expression of THRA mRNA; Polybrominated Biphenyls inhibits the reaction [Triiodothyronine results in increased activity of THRA protein]; Polybrominated Biphenyls metabolite inhibits the reaction [Triiodothyronine binds to THRA protein]; THRA protein alternative form affects the reaction [Triiodothyronine promotes the reaction [Thiazolidinediones results in increased expression of UCP2]]; Triiodothyronine binds to and results in increased activity of THRA protein Triiodothyronine results in decreased expression of THRA mRNA Triiodothyronine results in increased expression of THRA mRNA; Triiodothyronine results in increased expression of THRA protein |
CTD |
PMID:7684602 PMID:9664232 PMID:11806713 PMID:12109914 PMID:12414890 PMID:12588052 PMID:15680168 PMID:15708448 PMID:16021636 PMID:16023420 PMID:16738222 PMID:19672399 PMID:21396401 PMID:21726595 PMID:22015988 PMID:22086976 PMID:23112079 PMID:23402801 PMID:24076165 PMID:24262987 PMID:24819616 PMID:25646720 PMID:27993100 PMID:28167136 PMID:29146198 PMID:29688519 PMID:31566444 PMID:32223187 PMID:33095664 |
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NCBI chr10:86,657,285...86,684,935
Ensembl chr10:86,657,285...86,684,933
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G |
Thrb |
thyroid hormone receptor beta |
multiple interactions decreases expression affects binding increases response to substance increases activity increases expression |
ISO EXP |
(4-(4-hydroxy-3-isopropyl-5-(4-nitrophenylethynyl)benzyl)-3,5-dimethylphenoxy)acetic acid inhibits the reaction [Triiodothyronine results in increased expression of THRB mRNA]; 2,2',4,4'-tetrabromodiphenyl ether analog affects the reaction [Triiodothyronine binds to THRB protein]; 2,2',4,4'-tetrabromodiphenyl ether metabolite inhibits the reaction [Triiodothyronine binds to THRB protein]; 2,3,4,7,8-pentachlorodibenzofuran inhibits the reaction [Triiodothyronine results in increased expression of THRB mRNA]; 2,4,6-tribromophenol inhibits the reaction [Triiodothyronine binds to THRB protein]; 2,4,6-trichlorophenol inhibits the reaction [Triiodothyronine binds to THRB protein]; 2,4,6-triiodophenol inhibits the reaction [Triiodothyronine binds to THRB protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Triiodothyronine inhibits the reaction [THRB protein binds to NCOR1 protein]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Triiodothyronine inhibits the reaction [THRB protein binds to NCOR2 protein]]; 4,4'-hexafluorisopropylidene diphenol inhibits the reaction [Triiodothyronine binds to THRB protein]; 4-nonylphenol inhibits the reaction [Triiodothyronine results in increased activity of THRB protein]; 4-OH-2',3,3',4',5'-pentachlorobiphenyl inhibits the reaction [Triiodothyronine results in increased expression of THRB mRNA]; 6-OH-BDE-47 inhibits the reaction [Triiodothyronine binds to THRB protein]; [THRB protein co-treated with Triiodothyronine] results in increased expression of ANGPTL8 mRNA; [Triiodothyronine co-treated with NCOA1 protein] results in increased activity of THRB protein; AG 1879 inhibits the reaction [Triiodothyronine inhibits the reaction [THRB protein binds to NCOR1 protein]]; AG 1879 inhibits the reaction [Triiodothyronine inhibits the reaction [THRB protein binds to NCOR2 protein]]; Amiodarone inhibits the reaction [Triiodothyronine results in increased activity of THRB protein]; bis(4-hydroxyphenyl)sulfone analog inhibits the reaction [Triiodothyronine binds to THRB protein]; bis(4-hydroxyphenyl)sulfone analog inhibits the reaction [Triiodothyronine results in increased activity of THRB protein]; bis(4-hydroxyphenyl)sulfone inhibits the reaction [Triiodothyronine binds to THRB protein]; bis(4-hydroxyphenyl)sulfone inhibits the reaction [Triiodothyronine results in increased activity of THRB protein]; bisphenol A analog inhibits the reaction [Triiodothyronine binds to THRB protein]; bisphenol A inhibits the reaction [[Triiodothyronine co-treated with NCOA1 protein] results in increased activity of THRB protein]; bisphenol A inhibits the reaction [Triiodothyronine binds to THRB protein]; bisphenol A inhibits the reaction [Triiodothyronine inhibits the reaction [NCOR1 protein binds to and results in decreased activity of THRB protein]]; bisphenol A inhibits the reaction [Triiodothyronine inhibits the reaction [THRB protein binds to NCOR1 protein]]; bisphenol A inhibits the reaction [Triiodothyronine inhibits the reaction [THRB protein binds to NCOR2 protein]]; bisphenol A inhibits the reaction [Triiodothyronine results in increased activity of THRB protein]; bisphenol F inhibits the reaction [Triiodothyronine binds to THRB protein]; cyhalothrin inhibits the reaction [Triiodothyronine results in increased activity of THRB protein]; daidzein promotes the reaction [Triiodothyronine results in increased activity of THRB protein]; deoxynivalenol inhibits the reaction [Triiodothyronine results in increased activity of THRB protein]; desethylamiodarone inhibits the reaction [Triiodothyronine binds to THRB protein alternative form]; Genistein promotes the reaction [Triiodothyronine results in increased activity of THRB protein]; ITGB3 inhibits the reaction [bisphenol A inhibits the reaction [Triiodothyronine inhibits the reaction [NCOR1 protein binds to and results in decreased activity of THRB protein]]]; ITGB3 inhibits the reaction [bisphenol A inhibits the reaction [Triiodothyronine inhibits the reaction [NCOR2 protein binds to and results in decreased activity of THRB protein]]]; KB 130015 inhibits the reaction [Triiodothyronine binds to and results in increased activity of THRB protein]; methoxyacetic acid promotes the reaction [Triiodothyronine results in increased activity of THRB protein]; pentabromodiphenyl ether analog inhibits the reaction [Triiodothyronine binds to THRB protein]; pentabromophenol inhibits the reaction [Triiodothyronine binds to THRB protein]; Polybrominated Biphenyls metabolite inhibits the reaction [Triiodothyronine results in increased activity of THRB protein]; SRC inhibits the reaction [bisphenol A inhibits the reaction [Triiodothyronine inhibits the reaction [NCOR1 protein binds to and results in decreased activity of THRB protein]]]; SRC inhibits the reaction [bisphenol A inhibits the reaction [Triiodothyronine inhibits the reaction [NCOR2 protein binds to and results in decreased activity of THRB protein]]]; systhane inhibits the reaction [Triiodothyronine results in increased activity of THRB protein]; T-2 Toxin inhibits the reaction [Triiodothyronine results in increased activity of THRB protein]; tetrabromobisphenol A inhibits the reaction [Triiodothyronine binds to THRB protein]; tetrabromobisphenol A inhibits the reaction [Triiodothyronine results in increased activity of THRB protein]; tetrachlorodian analog inhibits the reaction [Triiodothyronine binds to THRB protein]; tetrachlorodian inhibits the reaction [Triiodothyronine results in increased activity of THRB protein]; tetraiodothyroacetic acid inhibits the reaction [Triiodothyronine inhibits the reaction [THRB protein binds to NCOR1 protein]]; tetraiodothyroacetic acid inhibits the reaction [Triiodothyronine inhibits the reaction [THRB protein binds to NCOR2 protein]]; Thyroxine inhibits the reaction [Triiodothyronine binds to THRB protein]; Tretinoin inhibits the reaction [Triiodothyronine results in increased activity of THRB protein]; tribromodiphenyl ether 28 analog affects the reaction [Triiodothyronine binds to THRB protein]; Triclosan inhibits the reaction [Triiodothyronine binds to THRB protein]; Triiodothyronine binds to and results in increased activity of THRB protein; Triiodothyronine inhibits the reaction [NCOR1 protein binds to and results in decreased activity of THRB protein]; Triiodothyronine inhibits the reaction [THRB protein binds to NCOR1 protein]; Triiodothyronine inhibits the reaction [THRB protein binds to NCOR2 protein]; Triiodothyronine inhibits the reaction [THRB protein results in increased expression of SOD1 mRNA]; Triiodothyronine promotes the reaction [NCOA2 protein binds to THRB protein]; Triiodothyronine promotes the reaction [THRB protein binds to NCOA2 protein]; Zearalenone inhibits the reaction [Triiodothyronine results in increased activity of THRB protein] Triiodothyronine results in decreased expression of THRB mRNA THRB protein results in increased susceptibility to Triiodothyronine THRB protein promotes the reaction [Triiodothyronine results in decreased expression of CDKN1B protein]; THRB protein promotes the reaction [Triiodothyronine results in increased expression of CCND1 protein]; THRB protein promotes the reaction [Triiodothyronine results in increased expression of PCNA protein] Triiodothyronine results in increased expression of THRB mRNA; Triiodothyronine results in increased expression of THRB protein [bisphenol A co-treated with Estradiol co-treated with Triiodothyronine] results in increased expression of THRB mRNA; [bisphenol A co-treated with Triiodothyronine] results in increased expression of THRB mRNA; Butyric Acid inhibits the reaction [Triiodothyronine results in increased expression of THRB mRNA]; desethylamiodarone inhibits the reaction [Triiodothyronine binds to THRB protein]; Polybrominated Biphenyls inhibits the reaction [Triiodothyronine results in increased activity of THRB protein]; THRB protein alternative form affects the reaction [Triiodothyronine promotes the reaction [Thiazolidinediones results in increased expression of UCP2]]; THRB protein promotes the reaction [Triiodothyronine results in increased expression of ATP2A2 mRNA]; Triiodothyronine inhibits the reaction [Phenylephrine results in decreased expression of THRB mRNA]; Triiodothyronine inhibits the reaction [Phenylephrine results in decreased expression of THRB protein] |
CTD |
PMID:2211641 PMID:8137729 PMID:11577024 PMID:11806713 PMID:12109914 PMID:12414890 PMID:12538616 PMID:12588052 PMID:15103026 PMID:15598685 PMID:15680168 PMID:15708448 PMID:16021636 PMID:16738222 PMID:18486176 PMID:18584933 PMID:18795168 PMID:19457453 PMID:19672399 PMID:20638743 PMID:20737425 PMID:21396401 PMID:22015988 PMID:22227104 PMID:23112079 PMID:23402801 PMID:24262987 PMID:25646720 PMID:27410513 PMID:27420076 PMID:27993100 PMID:28167136 PMID:28531659 PMID:28973306 PMID:29146198 PMID:29409039 PMID:29688519 PMID:29763311 PMID:31077750 PMID:31476497 PMID:31566444 PMID:33095664 |
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NCBI chr15:8,890,578...9,239,815
Ensembl chr15:8,890,578...9,086,282
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G |
Thrsp |
thyroid hormone responsive |
multiple interactions increases expression |
EXP ISO |
Triiodothyronine inhibits the reaction [Amiodarone results in increased expression of THRSP mRNA] Triiodothyronine results in increased expression of THRSP mRNA |
CTD |
PMID:2721112 PMID:10357836 PMID:15953391 PMID:28478156 |
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NCBI chr 1:162,381,251...162,385,575
Ensembl chr 1:162,381,253...162,385,575
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G |
Tmem184b |
transmembrane protein 184B |
multiple interactions |
ISO |
[Triiodothyronine co-treated with Tetrachlorodibenzodioxin] results in increased expression of TMEM184B mRNA |
CTD |
PMID:14761676 |
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NCBI chr 7:120,593,336...120,636,592
Ensembl chr 7:120,593,336...120,636,592
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G |
Tmem44 |
transmembrane protein 44 |
increases expression |
ISO |
Triiodothyronine results in increased expression of TMEM44 mRNA |
CTD |
PMID:23397585 |
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NCBI chr11:73,737,323...73,774,149
Ensembl chr11:73,738,433...73,774,190
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G |
Tnf |
tumor necrosis factor |
multiple interactions |
EXP ISO |
[Triiodothyronine co-treated with Hexachlorocyclohexane] results in increased expression of TNF mRNA; [Triiodothyronine co-treated with Hexachlorocyclohexane] results in increased expression of TNF protein; Hexachlorocyclohexane inhibits the reaction [Triiodothyronine results in increased expression of TNF protein] THRA protein affects the reaction [Triiodothyronine inhibits the reaction [Silicon Dioxide results in increased expression of TNF mRNA]]; THRA protein affects the reaction [Triiodothyronine inhibits the reaction [Silicon Dioxide results in increased secretion of TNF protein]]; Triiodothyronine inhibits the reaction [Silicon Dioxide results in increased expression of TNF mRNA]; Triiodothyronine inhibits the reaction [Silicon Dioxide results in increased secretion of TNF protein] |
CTD |
PMID:15019085 PMID:32223187 |
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NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 Ensembl chr20:5,189,390...5,192,000
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G |
Tnfrsf9 |
TNF receptor superfamily member 9 |
multiple interactions increases expression |
ISO |
4-OH-2',3,3',4',5'-pentachlorobiphenyl inhibits the reaction [Triiodothyronine results in increased expression of TNFRSF9 mRNA]; Polychlorinated Biphenyls inhibits the reaction [Triiodothyronine results in increased expression of TNFRSF9 mRNA]; Tetrachlorodibenzodioxin promotes the reaction [Triiodothyronine results in increased expression of TNFRSF9 mRNA]; Tetrachlorodibenzodioxin promotes the reaction [Triiodothyronine results in increased expression of TNFRSF9 protein] Triiodothyronine results in increased expression of TNFRSF9 mRNA; Triiodothyronine results in increased expression of TNFRSF9 protein |
CTD |
PMID:14761676 |
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NCBI chr 5:168,009,245...168,035,813
Ensembl chr 5:168,009,393...168,035,810
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G |
Tomm20 |
translocase of outer mitochondrial membrane 20 |
increases expression multiple interactions |
ISO |
Triiodothyronine results in increased expression of TOMM20 protein Chloroquine promotes the reaction [Triiodothyronine results in increased expression of TOMM20 protein]; Triiodothyronine promotes the reaction [bafilomycin A1 results in increased expression of TOMM20 protein] |
CTD |
PMID:30209975 |
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NCBI chr19:59,863,421...59,873,411
Ensembl chr19:59,863,421...59,873,411
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G |
Traf1 |
TNF receptor-associated factor 1 |
multiple interactions increases expression |
ISO |
4-OH-2',3,3',4',5'-pentachlorobiphenyl inhibits the reaction [Triiodothyronine results in increased expression of TRAF1 mRNA]; Polychlorinated Biphenyls inhibits the reaction [Triiodothyronine results in increased expression of TRAF1 mRNA]; Tetrachlorodibenzodioxin promotes the reaction [Triiodothyronine results in increased expression of TRAF1 mRNA]; Tetrachlorodibenzodioxin promotes the reaction [Triiodothyronine results in increased expression of TRAF1 protein] Triiodothyronine results in increased expression of TRAF1 mRNA; Triiodothyronine results in increased expression of TRAF1 protein |
CTD |
PMID:14761676 |
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NCBI chr 3:14,003,340...14,022,955
Ensembl chr 3:14,003,340...14,022,672
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G |
Trim46 |
tripartite motif-containing 46 |
increases expression |
ISO |
Triiodothyronine results in increased expression of TRIM46 mRNA |
CTD |
PMID:23397585 |
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NCBI chr 2:188,548,608...188,561,617
Ensembl chr 2:188,548,644...188,561,360
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G |
Tshb |
thyroid stimulating hormone subunit beta |
decreases expression multiple interactions increases secretion |
ISO EXP |
Triiodothyronine results in decreased expression of TSHB mRNA [Triiodothyronine co-treated with 2,2',4,4'-tetrabromodiphenyl ether] results in decreased expression of TSHB mRNA alternative form TSHB protein results in increased secretion of Triiodothyronine |
CTD |
PMID:7827627 PMID:9092800 PMID:11288978 PMID:27420076 PMID:28167136 |
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NCBI chr 2:205,207,799...205,215,199
Ensembl chr 2:205,207,799...205,212,681
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G |
Ttbk1 |
tau tubulin kinase 1 |
increases expression |
ISO |
Triiodothyronine results in increased expression of TTBK1 mRNA |
CTD |
PMID:25172293 |
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NCBI chr 9:16,862,305...16,899,399
Ensembl chr 9:16,862,248...16,902,199
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G |
Ttn |
titin |
multiple interactions affects expression |
EXP |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Triiodothyronine affects the expression of TTN mRNA]; AKT1 protein affects the reaction [Triiodothyronine affects the expression of TTN mRNA] |
CTD |
PMID:18096819 |
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NCBI chr 3:63,565,160...63,837,815
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G |
Ttr |
transthyretin |
affects binding |
ISO |
Triiodothyronine binds to TTR protein |
CTD |
PMID:20804816 PMID:21517007 |
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NCBI chr18:15,532,963...15,542,180
Ensembl chr18:15,532,963...15,540,177
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G |
Ucp1 |
uncoupling protein 1 |
multiple interactions increases expression |
ISO EXP |
(+)-JQ1 compound inhibits the reaction [[Triiodothyronine co-treated with rosiglitazone co-treated with INS1 protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of UCP1 mRNA]; [Triiodothyronine co-treated with rosiglitazone co-treated with INS1 protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of UCP1 mRNA Triiodothyronine results in increased expression of UCP1 mRNA; Triiodothyronine results in increased expression of UCP1 protein [AVP protein co-treated with Norepinephrine] inhibits the reaction [Triiodothyronine inhibits the reaction [EGF protein results in decreased expression of UCP1 mRNA]]; [AVP protein co-treated with Norepinephrine] inhibits the reaction [Triiodothyronine promotes the reaction [FGF1 protein results in increased expression of UCP1 mRNA]]; [AVP protein co-treated with Norepinephrine] inhibits the reaction [Triiodothyronine promotes the reaction [FGF2 protein results in increased expression of UCP1 mRNA]]; [AVP protein co-treated with Norepinephrine] inhibits the reaction [Triiodothyronine results in increased expression of UCP1 mRNA]; [EGF protein co-treated with AVP protein co-treated with Norepinephrine co-treated with Triiodothyronine] results in decreased expression of UCP1 mRNA; [FGF1 protein co-treated with AVP protein co-treated with Norepinephrine co-treated with Triiodothyronine] results in decreased expression of UCP1 mRNA; [Triiodothyronine co-treated with Norepinephrine] results in increased expression of UCP1 mRNA; AVP protein inhibits the reaction [Triiodothyronine inhibits the reaction [EGF protein results in decreased expression of UCP1 mRNA]]; AVP protein inhibits the reaction [Triiodothyronine promotes the reaction [FGF1 protein results in increased expression of UCP1 mRNA]]; AVP protein inhibits the reaction [Triiodothyronine promotes the reaction [FGF2 protein results in increased expression of UCP1 mRNA]]; AVP protein inhibits the reaction [Triiodothyronine results in increased expression of UCP1 mRNA]; Triiodothyronine inhibits the reaction [EGF protein results in decreased expression of UCP1 mRNA]; Triiodothyronine promotes the reaction [FGF1 protein results in increased expression of UCP1 mRNA]; Triiodothyronine promotes the reaction [FGF2 protein results in increased expression of UCP1 mRNA] |
CTD |
PMID:11742803 PMID:26972250 PMID:30209975 |
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NCBI chr19:24,456,976...24,464,808
Ensembl chr19:24,456,976...24,464,807
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G |
Ucp2 |
uncoupling protein 2 |
multiple interactions |
EXP |
THRA protein alternative form affects the reaction [Triiodothyronine promotes the reaction [Thiazolidinediones results in increased expression of UCP2]]; THRB protein alternative form affects the reaction [Triiodothyronine promotes the reaction [Thiazolidinediones results in increased expression of UCP2]]; Triiodothyronine promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of UCP2 mRNA]; Triiodothyronine promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of UCP2 protein]; Triiodothyronine promotes the reaction [Bezafibrate results in increased expression of UCP2 mRNA]; Triiodothyronine promotes the reaction [carboprostacyclin results in increased expression of UCP2 mRNA]; Triiodothyronine promotes the reaction [darglitazone results in increased expression of UCP2 mRNA] |
CTD |
PMID:12588052 PMID:25048947 |
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NCBI chr 1:165,506,375...165,512,744
Ensembl chr 1:165,506,361...165,512,744
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G |
Ugcg |
UDP-glucose ceramide glucosyltransferase |
increases activity |
EXP |
Triiodothyronine results in increased activity of UGCG protein |
CTD |
PMID:9101438 |
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NCBI chr 5:76,376,722...76,419,564
Ensembl chr 5:76,386,836...76,419,560
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G |
Ugt1a1 |
UDP glucuronosyltransferase family 1 member A1 |
decreases expression multiple interactions |
EXP |
Triiodothyronine results in decreased expression of UGT1A1 mRNA Vitamin A inhibits the reaction [Triiodothyronine results in decreased expression of UGT1A1 mRNA] |
CTD |
PMID:11299074 |
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NCBI chr 9:95,295,701...95,302,822
Ensembl chr 9:95,161,157...95,302,822
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G |
Ugt1a6 |
UDP glucuronosyltransferase family 1 member A6 |
increases expression multiple interactions |
EXP |
Triiodothyronine results in increased expression of UGT1A6 mRNA Vitamin A inhibits the reaction [Triiodothyronine results in increased expression of UGT1A6 mRNA] |
CTD |
PMID:11299074 |
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NCBI chr 9:95,241,609...95,302,822
Ensembl chr 9:95,161,157...95,302,822
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G |
Utp20 |
UTP20 small subunit processome component |
multiple interactions |
ISO |
[Triiodothyronine co-treated with Tetrachlorodibenzodioxin] results in decreased expression of UTP20 mRNA |
CTD |
PMID:14761676 |
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NCBI chr 7:29,296,360...29,378,105
Ensembl chr 7:29,296,963...29,378,080
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G |
Vdac1 |
voltage-dependent anion channel 1 |
increases expression multiple interactions |
ISO |
Triiodothyronine results in increased expression of VDAC1 protein Triiodothyronine promotes the reaction [bafilomycin A1 results in increased expression of VDAC1 protein] |
CTD |
PMID:30209975 |
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NCBI chr10:37,724,915...37,752,827
Ensembl chr10:37,724,915...37,752,826
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G |
Wls |
Wnt ligand secretion mediator |
increases expression |
ISO |
Triiodothyronine results in increased expression of WLS mRNA |
CTD |
PMID:23397585 |
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NCBI chr 2:266,315,036...266,431,220
Ensembl chr 2:266,315,036...266,432,558
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G |
Zc3h7b |
zinc finger CCCH-type containing 7B |
decreases expression |
ISO |
Triiodothyronine results in decreased expression of ZC3H7B mRNA |
CTD |
PMID:23397585 |
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NCBI chr 7:122,978,999...123,027,166
Ensembl chr 7:122,979,021...123,027,150
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G |
Zfp113 |
zinc finger protein 3 |
multiple interactions |
ISO |
[Triiodothyronine co-treated with Tetrachlorodibenzodioxin] results in decreased expression of ZNF3 mRNA |
CTD |
PMID:14761676 |
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NCBI chr12:19,287,541...19,298,172
Ensembl chr12:19,288,403...19,294,888
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G |
Zfp664 |
zinc finger protein 664 |
increases expression |
ISO |
Triiodothyronine results in increased expression of ZNF664 mRNA |
CTD |
PMID:23397585 |
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NCBI chr12:36,201,327...36,203,396
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G |
Zmiz1 |
zinc finger, MIZ-type containing 1 |
increases expression |
ISO |
Triiodothyronine results in increased expression of ZMIZ1 mRNA |
CTD |
PMID:23397585 |
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NCBI chr16:1,749,191...1,954,633
Ensembl chr16:1,749,191...1,954,614
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G |
Abcc2 |
ATP binding cassette subfamily C member 2 |
decreases abundance |
EXP |
ABCC2 results in decreased abundance of Thyroxine |
CTD |
PMID:19211616 |
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NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
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G |
Ahr |
aryl hydrocarbon receptor |
multiple interactions |
ISO |
AHR affects the reaction [2,4,6-triphenyl-1-hexene results in increased abundance of Thyroxine] |
CTD |
PMID:18560529 |
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NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
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G |
Alb |
albumin |
affects binding multiple interactions |
ISO |
Thyroxine binds to ALB protein 2,2',4,5'-tetrabromodiphenyl ether metabolite inhibits the reaction [Thyroxine binds to ALB protein]; Flame Retardants analog inhibits the reaction [Thyroxine binds to ALB protein] |
CTD |
PMID:20039755 PMID:21517007 PMID:29283575 |
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NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
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G |
Amh |
anti-Mullerian hormone |
multiple interactions |
EXP |
Thyroxine affects the reaction [Propylthiouracil affects the expression of AMH mRNA] |
CTD |
PMID:7819453 |
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NCBI chr 7:11,775,155...11,777,503
Ensembl chr 7:11,775,155...11,777,503
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G |
App |
amyloid beta precursor protein |
decreases cleavage decreases expression |
ISO |
Thyroxine results in decreased cleavage of APP protein Thyroxine results in decreased expression of APP mRNA; Thyroxine results in decreased expression of APP protein |
CTD |
PMID:17199430 |
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NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
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G |
Bad |
BCL2-associated agonist of cell death |
multiple interactions decreases expression |
ISO |
[nano-diamino-tetrac co-treated with Resveratrol] inhibits the reaction [Thyroxine results in decreased expression of BAD mRNA]; Resveratrol inhibits the reaction [Thyroxine results in decreased expression of BAD mRNA]; Thyroxine inhibits the reaction [Resveratrol results in increased expression of BAD mRNA] |
CTD |
PMID:31336132 PMID:31883986 |
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NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
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G |
Cat |
catalase |
multiple interactions decreases expression decreases activity |
EXP |
[Curcumin co-treated with Vitamin E] inhibits the reaction [Thyroxine results in decreased expression of CAT mRNA]; [Vitamin E co-treated with Curcumin] inhibits the reaction [Thyroxine results in decreased activity of CAT protein]; arotinolol promotes the reaction [Thyroxine results in decreased expression of CAT protein]; Atenolol promotes the reaction [Thyroxine results in decreased expression of CAT protein]; Curcumin inhibits the reaction [Thyroxine results in decreased expression of CAT mRNA]; Curcumin inhibits the reaction [Thyroxine results in decreased expression of CAT protein]; Vitamin E inhibits the reaction [Thyroxine results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Thyroxine results in decreased expression of CAT protein] Thyroxine results in decreased expression of CAT mRNA; Thyroxine results in decreased expression of CAT protein |
CTD |
PMID:2575990 PMID:18723006 PMID:19914224 |
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NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
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G |
Ccnd1 |
cyclin D1 |
increases expression multiple interactions |
ISO |
Thyroxine results in increased expression of CCND1 mRNA [Resveratrol co-treated with nano-diamino-tetrac] inhibits the reaction [Thyroxine results in increased expression of CCND1 mRNA]; nano-diamino-tetrac inhibits the reaction [Thyroxine results in increased expression of CCND1 mRNA]; Resveratrol inhibits the reaction [Thyroxine results in increased expression of CCND1 mRNA] |
CTD |
PMID:31336132 PMID:31883986 |
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NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
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G |
Cd274 |
CD274 molecule |
increases expression multiple interactions |
ISO |
Thyroxine results in increased expression of CD274 mRNA; Thyroxine results in increased expression of CD274 protein; Thyroxine results in increased expression of PDL1 mRNA; Thyroxine results in increased expression of PDL1 protein [Resveratrol co-treated with nano-diamino-tetrac] inhibits the reaction [Thyroxine results in increased expression of PDL1 mRNA]; nano-diamino-tetrac inhibits the reaction [Thyroxine results in increased expression of CD274 mRNA]; nano-diamino-tetrac inhibits the reaction [Thyroxine results in increased expression of CD274 protein]; nano-diamino-tetrac inhibits the reaction [Thyroxine results in increased expression of PDL1 mRNA]; NSC 74859 inhibits the reaction [Thyroxine results in increased expression of PDL1 protein]; Resveratrol inhibits the reaction [Thyroxine results in increased expression of PDL1 mRNA]; Resveratrol inhibits the reaction [Thyroxine results in increased expression of PDL1 protein] |
CTD |
PMID:29960019 PMID:31336132 PMID:31883986 |
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NCBI chr 1:247,519,890...247,539,659
Ensembl chr 1:247,519,939...247,537,943
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
multiple interactions |
ISO |
Thyroxine inhibits the reaction [resveratrol results in increased expression of CDKN1A mRNA] |
CTD |
PMID:17174366 |
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NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
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G |
Cyp2c79 |
cytochrome P450, family 2, subfamily c, polypeptide 79 |
decreases activity |
ISO |
Thyroxine results in decreased activity of CYP2C8 protein |
CTD |
PMID:15601807 |
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NCBI chr 1:147,236,480...147,307,988
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G |
Cyp3a62 |
cytochrome P450, family 3, subfamily a, polypeptide 62 |
multiple interactions |
ISO |
[Thyroxine results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA |
CTD |
PMID:25455453 |
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NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397
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G |
Cyp8b1 |
cytochrome P450 family 8 subfamily B member 1 |
decreases expression |
EXP |
Thyroxine results in decreased expression of CYP8B1 mRNA |
CTD |
PMID:10393316 |
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NCBI chr 8:130,548,418...130,550,388
Ensembl chr 8:130,548,418...130,550,388
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G |
Dcn |
decorin |
decreases expression |
ISO |
Thyroxine results in decreased expression of DCN mRNA |
CTD |
PMID:23935926 |
|
NCBI chr 7:38,742,250...38,782,282
Ensembl chr 7:38,742,051...38,782,323
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G |
Dio1 |
iodothyronine deiodinase 1 |
affects abundance multiple interactions increases expression affects metabolic processing increases metabolic processing |
ISO EXP |
DIO1 gene SNP affects the abundance of Thyroxine 2,2',4,4'-tetrabromodiphenyl ether inhibits the reaction [Thyroxine results in increased expression of DIO1 mRNA] DIO1 protein affects the metabolism of Thyroxine [DIO1 protein results in increased metabolism of Thyroxine] which results in increased abundance of Triiodothyronine; Iodoacetates inhibits the reaction [[DIO1 protein results in increased metabolism of Thyroxine] which results in increased abundance of Triiodothyronine] |
CTD |
PMID:15254343 PMID:17105838 PMID:21565810 PMID:27420076 |
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NCBI chr 5:126,894,837...126,911,532
Ensembl chr 5:126,895,286...126,911,520
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G |
Dio2 |
iodothyronine deiodinase 2 |
multiple interactions decreases expression decreases activity increases metabolic processing affects metabolic processing |
ISO EXP |
2,2',4,4',5-brominated diphenyl ether inhibits the reaction [[DIO2 protein results in increased metabolism of Thyroxine] which results in increased chemical synthesis of Triiodothyronine]; 2,2',4,4',5-brominated diphenyl ether metabolite inhibits the reaction [[DIO2 protein results in increased metabolism of Thyroxine] which results in increased chemical synthesis of Triiodothyronine]; 2,2',4,4'-tetrabromodiphenyl ether metabolite inhibits the reaction [[DIO2 protein results in increased metabolism of Thyroxine] which results in increased chemical synthesis of Triiodothyronine]; [DIO2 protein results in increased metabolism of Thyroxine] which results in increased chemical synthesis of Triiodothyronine; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Thyroxine results in decreased activity of DIO2 protein]; lactacystin inhibits the reaction [Thyroxine results in decreased activity of DIO2 protein]; Thyroxine results in decreased expression of and results in decreased activity of DIO2 protein 2,2',4,4'-tetrabromodiphenyl ether inhibits the reaction [Thyroxine results in decreased expression of DIO2 mRNA] DIO2 protein mutant form affects the metabolism of Thyroxine |
CTD |
PMID:11108274 PMID:11425850 PMID:16728495 PMID:17615150 PMID:26004626 PMID:27420076 |
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NCBI chr 6:114,475,156...114,489,443
Ensembl chr 6:114,476,142...114,476,723
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G |
Dio3 |
iodothyronine deiodinase 3 |
increases activity multiple interactions |
EXP |
Thyroxine results in increased activity of DIO3 protein Hydrogen Peroxide promotes the reaction [Thyroxine results in increased activity of DIO3 protein] |
CTD |
PMID:18420745 |
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NCBI chr 6:134,627,278...134,629,139
Ensembl chr 6:134,627,278...134,629,138
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G |
Dmp1 |
dentin matrix acidic phosphoprotein 1 |
increases expression |
ISO |
Thyroxine results in increased expression of DMP1 mRNA |
CTD |
PMID:23935926 |
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NCBI chr14:6,889,851...6,923,961
Ensembl chr14:6,889,856...6,900,733
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G |
Duox1 |
dual oxidase 1 |
decreases expression |
ISO |
Thyroxine results in decreased expression of DUOX1 protein |
CTD |
PMID:17332529 |
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NCBI chr 3:114,251,794...114,286,827
Ensembl chr 3:114,253,637...114,286,802
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G |
Duox2 |
dual oxidase 2 |
decreases expression |
ISO |
Thyroxine results in decreased expression of DUOX2 protein |
CTD |
PMID:17332529 |
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NCBI chr 3:114,218,187...114,237,808
Ensembl chr 3:114,218,193...114,235,933
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G |
Fgf1 |
fibroblast growth factor 1 |
increases expression |
ISO |
Thyroxine results in increased expression of FGF1 mRNA |
CTD |
PMID:23935926 |
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NCBI chr18:32,273,830...32,359,831
Ensembl chr18:32,273,770...32,359,824
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G |
Fgf2 |
fibroblast growth factor 2 |
increases expression |
ISO |
Thyroxine results in increased expression of FGF2 mRNA |
CTD |
PMID:23935926 |
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NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
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G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
ISO |
Thyroxine inhibits the reaction [resveratrol results in increased expression of FOS mRNA] |
CTD |
PMID:17174366 |
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NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
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G |
Gap43 |
growth associated protein 43 |
increases expression multiple interactions |
EXP |
Thyroxine results in increased expression of GAP43 mRNA Thyroxine inhibits the reaction [Ethanol results in decreased expression of GAP43 mRNA] |
CTD |
PMID:15940294 |
|
NCBI chr11:58,624,198...58,717,916
Ensembl chr11:58,624,198...58,717,914
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G |
Gh1 |
growth hormone 1 |
decreases abundance multiple interactions |
ISO |
GH1 protein results in decreased abundance of Thyroxine [2,2',4,4'-tetrabromodiphenyl ether co-treated with Thyroxine] results in increased expression of GH mRNA |
CTD |
PMID:17311540 PMID:17324600 PMID:27420076 |
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NCBI chr10:94,486,204...94,488,181
Ensembl chr10:94,486,205...94,488,180
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G |
Gpd2 |
glycerol-3-phosphate dehydrogenase 2 |
multiple interactions |
EXP |
Ipodate inhibits the reaction [Thyroxine results in increased activity of GPD2 protein]; Propylthiouracil inhibits the reaction [Thyroxine results in increased activity of GPD2 protein] |
CTD |
PMID:6723573 |
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NCBI chr 3:43,223,892...43,359,069
Ensembl chr 3:43,255,567...43,359,074
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G |
Gpx1 |
glutathione peroxidase 1 |
multiple interactions increases activity decreases activity increases expression decreases expression |
EXP |
[Curcumin co-treated with Vitamin E] inhibits the reaction [Thyroxine results in increased expression of GPX1 protein]; Curcumin inhibits the reaction [Thyroxine results in decreased expression of GPX1 mRNA]; Vitamin E inhibits the reaction [Thyroxine results in decreased expression of GPX1 mRNA] Thyroxine results in increased activity of GPX1 protein Thyroxine results in decreased activity of GPX1 protein |
CTD |
PMID:19914224 |
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NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
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G |
Gsr |
glutathione-disulfide reductase |
multiple interactions decreases activity decreases expression |
EXP |
[Curcumin co-treated with Vitamin E] inhibits the reaction [Thyroxine results in decreased expression of GSR mRNA]; Curcumin inhibits the reaction [Thyroxine results in decreased expression of GSR mRNA]; Vitamin E inhibits the reaction [Thyroxine results in decreased expression of GSR mRNA] Thyroxine results in decreased activity of GSR protein Thyroxine results in decreased expression of GSR mRNA; Thyroxine results in decreased expression of GSR protein |
CTD |
PMID:19914224 |
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NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
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G |
Hes1 |
hes family bHLH transcription factor 1 |
multiple interactions |
EXP |
[Propylthiouracil results in increased abundance of Thyroxine] which results in increased expression of HES1 mRNA |
CTD |
PMID:15862623 |
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NCBI chr11:74,312,837...74,315,249
Ensembl chr11:74,312,806...74,315,248
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G |
Hes5 |
hes family bHLH transcription factor 5 |
multiple interactions |
EXP |
[Propylthiouracil results in increased abundance of Thyroxine] which results in increased expression of HES5 mRNA |
CTD |
PMID:15862623 |
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NCBI chr 5:172,364,421...172,365,188
Ensembl chr 5:172,364,421...172,365,188
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G |
Hr |
HR, lysine demethylase and nuclear receptor corepressor |
increases expression |
EXP |
Thyroxine results in increased expression of HR mRNA |
CTD |
PMID:29901742 |
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NCBI chr15:52,241,801...52,261,276
Ensembl chr15:52,241,801...52,261,276
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G |
Htra1 |
HtrA serine peptidase 1 |
increases expression |
ISO |
Thyroxine results in increased expression of HTRA1 mRNA |
CTD |
PMID:23935926 |
|
NCBI chr 1:201,499,067...201,548,508
Ensembl chr 1:201,499,028...201,548,513
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G |
Igf1 |
insulin-like growth factor 1 |
increases expression |
ISO |
Thyroxine results in increased expression of IGF1 mRNA |
CTD |
PMID:23935926 |
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NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
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G |
Igf1r |
insulin-like growth factor 1 receptor |
multiple interactions increases expression |
EXP |
Vitamin E inhibits the reaction [Thyroxine results in increased expression of IGF1R protein] |
CTD |
PMID:17447016 |
|
NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
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G |
Il1b |
interleukin 1 beta |
multiple interactions increases expression |
ISO |
NSC 74859 inhibits the reaction [Thyroxine results in increased expression of IL1B mRNA] |
CTD |
PMID:31336132 |
|
NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
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G |
Itgb3 |
integrin subunit beta 3 |
multiple interactions |
ISO |
ITGB3 inhibits the reaction [bisphenol A inhibits the reaction [Thyroxine inhibits the reaction [NCOR1 protein binds to and results in decreased activity of THRB protein]]]; ITGB3 inhibits the reaction [bisphenol A inhibits the reaction [Thyroxine inhibits the reaction [NCOR2 protein binds to and results in decreased activity of THRB protein]]] |
CTD |
PMID:22227104 |
|
NCBI chr10:92,667,869...92,783,413
Ensembl chr10:92,667,869...92,783,410
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G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
ISO |
Thyroxine inhibits the reaction [resveratrol results in increased expression of JUN mRNA] |
CTD |
PMID:17174366 |
|
NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions increases phosphorylation affects localization |
ISO EXP |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Thyroxine results in increased phosphorylation of and results in increased activity of MAPK1 protein]; NSC 74859 inhibits the reaction [Thyroxine results in increased phosphorylation of MAPK1 protein]; tetraiodothyroacetic acid inhibits the reaction [Thyroxine results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Thyroxine results in increased phosphorylation of and results in increased activity of MAPK1 protein Thyroxine affects the localization of MAPK1 protein tetraiodothyroacetic acid inhibits the reaction [Thyroxine affects the localization of MAPK1 protein] |
CTD |
PMID:17174366 PMID:17984113 PMID:31336132 |
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NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions increases phosphorylation affects localization |
ISO EXP |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Thyroxine results in increased phosphorylation of and results in increased activity of MAPK3 protein]; NSC 74859 inhibits the reaction [Thyroxine results in increased phosphorylation of MAPK3 protein]; tetraiodothyroacetic acid inhibits the reaction [Thyroxine results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Thyroxine results in increased phosphorylation of and results in increased activity of MAPK3 protein Thyroxine affects the localization of MAPK3 protein tetraiodothyroacetic acid inhibits the reaction [Thyroxine affects the localization of MAPK3 protein] |
CTD |
PMID:17174366 PMID:17984113 PMID:31336132 |
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NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
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G |
Mmp9 |
matrix metallopeptidase 9 |
increases expression |
ISO |
Thyroxine results in increased expression of MMP9 mRNA |
CTD |
PMID:23935926 |
|
NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
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G |
Ncoa2 |
nuclear receptor coactivator 2 |
multiple interactions |
ISO |
Thyroxine promotes the reaction [THRA protein binds to NCOA2 protein]; Thyroxine promotes the reaction [THRB protein binds to NCOA2 protein] |
CTD |
PMID:31566444 |
|
NCBI chr 5:5,466,544...5,696,540
Ensembl chr 5:5,616,483...5,694,598
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G |
Ncor1 |
nuclear receptor co-repressor 1 |
multiple interactions |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Thyroxine inhibits the reaction [THRB protein binds to NCOR1 protein]]; AG 1879 inhibits the reaction [Thyroxine inhibits the reaction [THRB protein binds to NCOR1 protein]]; bisphenol A inhibits the reaction [Thyroxine inhibits the reaction [NCOR1 protein binds to and results in decreased activity of THRB protein]]; bisphenol A inhibits the reaction [Thyroxine inhibits the reaction [THRB protein binds to NCOR1 protein]]; ITGB3 inhibits the reaction [bisphenol A inhibits the reaction [Thyroxine inhibits the reaction [NCOR1 protein binds to and results in decreased activity of THRB protein]]]; SRC inhibits the reaction [bisphenol A inhibits the reaction [Thyroxine inhibits the reaction [NCOR1 protein binds to and results in decreased activity of THRB protein]]]; tetraiodothyroacetic acid inhibits the reaction [Thyroxine inhibits the reaction [THRB protein binds to NCOR1 protein]]; Thyroxine inhibits the reaction [NCOR1 protein binds to and results in decreased activity of THRB protein]; Thyroxine inhibits the reaction [THRB protein binds to NCOR1 protein] |
CTD |
PMID:22227104 |
|
NCBI chr10:48,629,121...48,772,890
Ensembl chr10:48,629,121...48,772,890
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G |
Ncor2 |
nuclear receptor co-repressor 2 |
multiple interactions |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Thyroxine inhibits the reaction [THRB protein binds to NCOR2 protein]]; AG 1879 inhibits the reaction [Thyroxine inhibits the reaction [THRB protein binds to NCOR2 protein]]; bisphenol A inhibits the reaction [Thyroxine inhibits the reaction [THRB protein binds to NCOR2 protein]]; ITGB3 inhibits the reaction [bisphenol A inhibits the reaction [Thyroxine inhibits the reaction [NCOR2 protein binds to and results in decreased activity of THRB protein]]]; SRC inhibits the reaction [bisphenol A inhibits the reaction [Thyroxine inhibits the reaction [NCOR2 protein binds to and results in decreased activity of THRB protein]]]; tetraiodothyroacetic acid inhibits the reaction [Thyroxine inhibits the reaction [THRB protein binds to NCOR2 protein]]; Thyroxine inhibits the reaction [THRB protein binds to NCOR2 protein] |
CTD |
PMID:22227104 |
|
NCBI chr12:36,871,917...37,033,701
Ensembl chr12:36,871,999...37,033,701
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G |
Nr1i2 |
nuclear receptor subfamily 1, group I, member 2 |
increases activity multiple interactions |
ISO |
Thyroxine results in increased activity of NR1I2 protein [Thyroxine results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA |
CTD |
PMID:25455453 |
|
NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
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G |
Nr1i3 |
nuclear receptor subfamily 1, group I, member 3 |
affects metabolic processing |
ISO |
NR1I3 protein affects the metabolism of Thyroxine |
CTD |
PMID:15004031 |
|
NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
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G |
Nr3c1 |
nuclear receptor subfamily 3, group C, member 1 |
multiple interactions increases expression |
EXP |
Thyroxine inhibits the reaction [Ethanol results in decreased expression of NR3C1 mRNA] Thyroxine results in increased expression of NR3C1 mRNA |
CTD |
PMID:15940294 |
|
NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
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G |
Odc1 |
ornithine decarboxylase 1 |
multiple interactions |
EXP |
Ipodate inhibits the reaction [Thyroxine results in increased activity of ODC1 protein]; Propylthiouracil inhibits the reaction [Thyroxine results in increased activity of ODC1 protein] |
CTD |
PMID:6723573 |
|
NCBI chr 6:42,852,529...42,859,142
Ensembl chr 6:42,852,683...42,859,927
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G |
Pcna |
proliferating cell nuclear antigen |
multiple interactions increases expression |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Thyroxine results in increased expression of PCNA protein] |
CTD |
PMID:17174366 |
|
NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
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G |
Pcsk2 |
proprotein convertase subtilisin/kexin type 2 |
decreases expression |
EXP |
Thyroxine results in decreased expression of PCSK2 mRNA |
CTD |
PMID:15585599 |
|
NCBI chr 3:137,618,891...137,923,385
Ensembl chr 3:137,618,898...137,925,605
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G |
Phex |
phosphate regulating endopeptidase homolog, X-linked |
increases expression |
ISO |
Thyroxine results in increased expression of PHEX mRNA |
CTD |
PMID:23935926 |
|
NCBI chr X:40,460,047...40,717,982
Ensembl chr X:40,460,047...40,717,982
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G |
Pmp22 |
peripheral myelin protein 22 |
increases expression |
ISO EXP |
Thyroxine results in increased expression of PMP22 mRNA |
CTD |
PMID:29901742 |
|
NCBI chr10:49,538,588...49,568,583
Ensembl chr10:49,538,588...49,568,583
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G |
Por |
cytochrome p450 oxidoreductase |
increases expression |
ISO |
Thyroxine results in increased expression of POR mRNA |
CTD |
PMID:23935926 |
|
NCBI chr12:23,998,411...24,017,063
Ensembl chr12:23,998,411...24,046,814
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
multiple interactions |
ISO |
Thyroxine inhibits the reaction [Triclosan results in decreased expression of PPARG protein] |
CTD |
PMID:28973666 |
|
NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions decreases expression |
EXP ISO |
Thyroxine inhibits the reaction [resveratrol affects the localization of PTGS2 protein] Thyroxine results in decreased expression of PTGS2 mRNA [Resveratrol co-treated with nano-diamino-tetrac] promotes the reaction [Thyroxine results in decreased expression of PTGS2 mRNA]; nano-diamino-tetrac promotes the reaction [Thyroxine results in decreased expression of PTGS2 mRNA]; Resveratrol inhibits the reaction [Thyroxine results in decreased expression of PTGS2 mRNA]; Thyroxine inhibits the reaction [Resveratrol affects the localization of PTGS2 protein]; Thyroxine inhibits the reaction [Resveratrol results in increased expression of PTGS2 mRNA] |
CTD |
PMID:17984113 PMID:31336132 PMID:31883986 |
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NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
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G |
Rxra |
retinoid X receptor alpha |
affects binding |
ISO |
Thyroxine binds to RXRA protein |
CTD |
PMID:31566444 |
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NCBI chr 3:6,272,560...6,295,354
Ensembl chr 3:6,211,789...6,295,908
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G |
Sema7a |
semaphorin 7A (John Milton Hagen blood group) |
increases expression |
EXP |
Thyroxine results in increased expression of SEMA7A mRNA |
CTD |
PMID:29901742 |
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NCBI chr 8:62,723,788...62,746,530
Ensembl chr 8:62,723,788...62,745,868
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G |
Serpina7 |
serpin family A member 7 |
multiple interactions affects binding |
ISO |
3,5-dichlorobiphenyl metabolite inhibits the reaction [Thyroxine binds to SERPINA7 protein]; bisphenol A inhibits the reaction [Thyroxine binds to SERPINA7 protein]; tetrabromobisphenol A inhibits the reaction [Thyroxine binds to SERPINA7 protein]; tetrachlorodian inhibits the reaction [Thyroxine binds to SERPINA7 protein] |
CTD |
PMID:16478101 PMID:20804816 PMID:21517007 PMID:27528273 |
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NCBI chr X:110,226,565...110,232,202
Ensembl chr X:110,226,572...110,232,179
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G |
Shh |
sonic hedgehog signaling molecule |
increases expression |
EXP |
Thyroxine results in increased expression of SHH mRNA |
CTD |
PMID:29901742 |
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NCBI chr 4:718,538...727,691
Ensembl chr 4:718,538...727,691
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G |
Sirt1 |
sirtuin 1 |
increases expression |
ISO |
Thyroxine results in increased expression of SIRT1 protein |
CTD |
PMID:18204789 |
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NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
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G |
Slc2a4 |
solute carrier family 2 member 4 |
multiple interactions |
ISO |
Thyroxine inhibits the reaction [Triclosan results in decreased expression of SLC2A4 protein] |
CTD |
PMID:28973666 |
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NCBI chr10:56,552,921...56,558,562
Ensembl chr10:56,552,983...56,558,487
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G |
Slc30a10 |
solute carrier family 30, member 10 |
decreases chemical synthesis |
ISO |
SLC30A10 gene mutant form results in decreased chemical synthesis of Thyroxine |
CTD |
PMID:28860195 |
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NCBI chr13:103,396,295...103,406,759
Ensembl chr13:103,396,314...103,410,363
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G |
Slc5a5 |
solute carrier family 5 member 5 |
decreases expression |
ISO |
Thyroxine results in decreased expression of SLC5A5 protein |
CTD |
PMID:17332529 |
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NCBI chr16:20,297,414...20,307,401
Ensembl chr16:20,297,414...20,307,400
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G |
Sod1 |
superoxide dismutase 1 |
multiple interactions increases expression increases activity decreases activity decreases expression |
EXP |
[Curcumin co-treated with Vitamin E] inhibits the reaction [Thyroxine results in decreased expression of SOD1 mRNA]; [Curcumin co-treated with Vitamin E] inhibits the reaction [Thyroxine results in increased activity of SOD1 protein]; [Curcumin co-treated with Vitamin E] promotes the reaction [Thyroxine results in decreased activity of SOD1 protein]; Atenolol promotes the reaction [Thyroxine results in decreased expression of SOD1 protein]; Curcumin inhibits the reaction [Thyroxine results in decreased expression of SOD1 mRNA]; Curcumin inhibits the reaction [Thyroxine results in increased activity of SOD1 protein]; Curcumin promotes the reaction [Thyroxine results in decreased activity of SOD1 protein]; Thyroxine inhibits the reaction [Zinc deficiency results in increased activity of SOD1 protein]; Vitamin E inhibits the reaction [Thyroxine results in decreased expression of SOD1 mRNA]; Vitamin E inhibits the reaction [Thyroxine results in decreased expression of SOD1 protein]; Vitamin E inhibits the reaction [Thyroxine results in increased activity of SOD1 protein]; Vitamin E inhibits the reaction [Thyroxine results in increased expression of SOD1 protein]; Vitamin E promotes the reaction [Thyroxine results in decreased activity of SOD1 protein] Thyroxine results in decreased expression of SOD1 mRNA; Thyroxine results in decreased expression of SOD1 protein |
CTD |
PMID:2575990 PMID:10381190 PMID:17447016 PMID:19914224 |
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NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
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G |
Sod2 |
superoxide dismutase 2 |
multiple interactions decreases activity decreases expression increases expression |
EXP |
[Vitamin E co-treated with Curcumin] inhibits the reaction [Thyroxine results in decreased expression of SOD2 mRNA]; Atenolol inhibits the reaction [Thyroxine results in increased expression of SOD2 protein]; Curcumin inhibits the reaction [Thyroxine results in decreased activity of SOD2 protein]; Curcumin promotes the reaction [Thyroxine results in increased expression of SOD2 protein]; Vitamin E inhibits the reaction [Thyroxine results in decreased expression of SOD2 mRNA]; Vitamin E promotes the reaction [Thyroxine results in increased expression of SOD2 protein] |
CTD |
PMID:2575990 PMID:19914224 |
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NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
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G |
Src |
SRC proto-oncogene, non-receptor tyrosine kinase |
multiple interactions |
ISO |
SRC inhibits the reaction [bisphenol A inhibits the reaction [Thyroxine inhibits the reaction [NCOR1 protein binds to and results in decreased activity of THRB protein]]]; SRC inhibits the reaction [bisphenol A inhibits the reaction [Thyroxine inhibits the reaction [NCOR2 protein binds to and results in decreased activity of THRB protein]]] |
CTD |
PMID:22227104 |
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NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642
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G |
Stat3 |
signal transducer and activator of transcription 3 |
multiple interactions increases phosphorylation |
ISO |
NSC 74859 inhibits the reaction [Thyroxine results in increased phosphorylation of STAT3 protein] |
CTD |
PMID:31336132 |
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NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
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G |
Sult1a1 |
sulfotransferase family 1A member 1 |
affects sulfation multiple interactions increases sulfation |
ISO |
SULT1A1 gene polymorphism affects the sulfation of Thyroxine Thyroxine inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol] SULT1A1 protein results in increased sulfation of Thyroxine |
CTD |
PMID:11739018 PMID:15531517 |
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NCBI chr 1:198,100,586...198,104,106
Ensembl chr 1:198,100,586...198,104,109
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G |
Sult4a1 |
sulfotransferase family 4A, member 1 |
increases metabolic processing |
ISO |
SULT4A1 protein results in increased metabolism of Thyroxine |
CTD |
PMID:12039030 |
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NCBI chr 7:124,958,546...124,982,602
Ensembl chr 7:124,958,546...124,982,566
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G |
Syn1 |
synapsin I |
multiple interactions |
ISO |
Thyroxine inhibits the reaction [Phenytoin results in decreased expression of SYN1 mRNA] |
CTD |
PMID:27413119 |
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NCBI chr X:1,321,315...1,379,202
Ensembl chr X:1,321,315...1,379,198
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G |
Syp |
synaptophysin |
multiple interactions |
ISO |
Thyroxine inhibits the reaction [Phenytoin results in decreased expression of SYP mRNA] |
CTD |
PMID:27413119 |
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NCBI chr X:15,694,699...15,709,244
Ensembl chr X:15,695,566...15,707,436
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G |
Tgfb1 |
transforming growth factor, beta 1 |
multiple interactions increases expression |
ISO |
NSC 74859 inhibits the reaction [Thyroxine results in increased expression of TGFB1 mRNA]; Resveratrol inhibits the reaction [Thyroxine results in increased expression of TGFB1 mRNA] |
CTD |
PMID:31336132 |
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NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
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G |
Thra |
thyroid hormone receptor alpha |
affects binding multiple interactions increases expression |
ISO EXP |
Thyroxine binds to THRA protein Thyroxine promotes the reaction [THRA protein binds to NCOA2 protein] Thyroxine results in increased expression of THRA mRNA [bisphenol A co-treated with Estradiol co-treated with Thyroxine] results in increased expression of THRA mRNA; [bisphenol A co-treated with Thyroxine] results in increased expression of THRA mRNA |
CTD |
PMID:23112079 PMID:23402801 PMID:27993100 PMID:31566444 |
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NCBI chr10:86,657,285...86,684,935
Ensembl chr10:86,657,285...86,684,933
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G |
Thrb |
thyroid hormone receptor beta |
multiple interactions decreases expression increases expression increases activity affects binding |
ISO EXP |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Thyroxine inhibits the reaction [THRB protein binds to NCOR1 protein]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Thyroxine inhibits the reaction [THRB protein binds to NCOR2 protein]]; AG 1879 inhibits the reaction [Thyroxine inhibits the reaction [THRB protein binds to NCOR1 protein]]; AG 1879 inhibits the reaction [Thyroxine inhibits the reaction [THRB protein binds to NCOR2 protein]]; bisphenol A inhibits the reaction [Thyroxine inhibits the reaction [NCOR1 protein binds to and results in decreased activity of THRB protein]]; bisphenol A inhibits the reaction [Thyroxine inhibits the reaction [THRB protein binds to NCOR1 protein]]; bisphenol A inhibits the reaction [Thyroxine inhibits the reaction [THRB protein binds to NCOR2 protein]]; ITGB3 inhibits the reaction [bisphenol A inhibits the reaction [Thyroxine inhibits the reaction [NCOR1 protein binds to and results in decreased activity of THRB protein]]]; ITGB3 inhibits the reaction [bisphenol A inhibits the reaction [Thyroxine inhibits the reaction [NCOR2 protein binds to and results in decreased activity of THRB protein]]]; SRC inhibits the reaction [bisphenol A inhibits the reaction [Thyroxine inhibits the reaction [NCOR1 protein binds to and results in decreased activity of THRB protein]]]; SRC inhibits the reaction [bisphenol A inhibits the reaction [Thyroxine inhibits the reaction [NCOR2 protein binds to and results in decreased activity of THRB protein]]]; tetraiodothyroacetic acid inhibits the reaction [Thyroxine inhibits the reaction [THRB protein binds to NCOR1 protein]]; tetraiodothyroacetic acid inhibits the reaction [Thyroxine inhibits the reaction [THRB protein binds to NCOR2 protein]]; Thyroxine inhibits the reaction [NCOR1 protein binds to and results in decreased activity of THRB protein]; Thyroxine inhibits the reaction [THRB protein binds to NCOR1 protein]; Thyroxine inhibits the reaction [THRB protein binds to NCOR2 protein]; Thyroxine inhibits the reaction [Triiodothyronine binds to THRB protein]; Thyroxine promotes the reaction [THRB protein binds to NCOA2 protein] Thyroxine results in decreased expression of THRB mRNA Thyroxine results in increased expression of THRB mRNA [bisphenol A co-treated with Estradiol co-treated with Thyroxine] results in increased expression of THRB mRNA; [bisphenol A co-treated with Thyroxine] results in increased expression of THRB mRNA Thyroxine results in increased activity of THRB protein Thyroxine binds to THRB protein |
CTD |
PMID:18584933 PMID:19457453 PMID:22227104 PMID:23112079 PMID:23402801 PMID:27420076 PMID:27993100 PMID:29409039 PMID:31077750 PMID:31566444 |
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NCBI chr15:8,890,578...9,239,815
Ensembl chr15:8,890,578...9,086,282
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G |
Tnf |
tumor necrosis factor |
increases expression |
ISO |
Thyroxine results in increased expression of TNF mRNA |
CTD |
PMID:23935926 |
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NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 Ensembl chr20:5,189,390...5,192,000
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G |
Tp53 |
tumor protein p53 |
multiple interactions affects localization |
ISO EXP |
Thyroxine inhibits the reaction [resveratrol results in increased activity of TP53 protein] tetraiodothyroacetic acid inhibits the reaction [Thyroxine affects the localization of TP53 protein modified form] |
CTD |
PMID:17174366 PMID:17984113 |
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NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
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G |
Tpo |
thyroid peroxidase |
multiple interactions |
EXP |
[Propylthiouracil results in decreased activity of TPO protein] which results in decreased chemical synthesis of and results in decreased abundance of Thyroxine |
CTD |
PMID:28973696 |
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NCBI chr 6:49,020,918...49,089,855
Ensembl chr 6:49,021,044...49,089,855
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G |
Trpm7 |
transient receptor potential cation channel, subfamily M, member 7 |
decreases abundance |
ISO |
TRPM7 gene mutant form results in decreased abundance of Thyroxine |
CTD |
PMID:30770447 |
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NCBI chr 3:119,258,189...119,347,084
Ensembl chr 3:119,259,467...119,330,345
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G |
Tshb |
thyroid stimulating hormone subunit beta |
multiple interactions decreases expression |
EXP ISO |
Clofibrate inhibits the reaction [Thyroxine results in decreased expression of TSHB protein]; Thyroxine inhibits the reaction [lead acetate results in decreased expression of TSHB protein] Thyroxine results in decreased expression of TSHB mRNA |
CTD |
PMID:18219302 PMID:21871911 PMID:27420076 |
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NCBI chr 2:205,207,799...205,215,199
Ensembl chr 2:205,207,799...205,212,681
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G |
Tshr-ps1 |
thyroid stimulating hormone receptor, pseudogene 1 |
decreases activity |
ISO |
Thyroxine results in decreased activity of TSHR protein |
CTD |
PMID:17332529 |
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NCBI chr 4:93,447,412...93,448,194
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G |
Ttr |
transthyretin |
multiple interactions affects binding |
ISO EXP |
2,2',3',4,4',5-hexachlorobiphenyl inhibits the reaction [Thyroxine binds to TTR protein]; 2,2',3,3',4,4',5-heptachlorobiphenyl inhibits the reaction [Thyroxine binds to TTR protein]; 2,2',4,4'-tetrabromodiphenyl ether analog inhibits the reaction [Thyroxine binds to TTR protein]; 2,2',4,4'-tetrabromodiphenyl ether inhibits the reaction [Thyroxine binds to TTR protein]; 2,2',4,5'-tetrabromodiphenyl ether metabolite inhibits the reaction [Thyroxine binds to TTR protein]; 2,4,5,2',4',5'-hexachlorobiphenyl inhibits the reaction [Thyroxine binds to TTR protein]; 3,5-dichlorobiphenyl metabolite inhibits the reaction [Thyroxine binds to TTR protein]; 4-nonylphenol inhibits the reaction [Thyroxine binds to TTR protein]; bisphenol A inhibits the reaction [Thyroxine binds to TTR protein]; Diethylstilbestrol inhibits the reaction [Thyroxine binds to TTR protein]; Flame Retardants analog inhibits the reaction [Thyroxine binds to TTR protein]; Flame Retardants inhibits the reaction [Thyroxine binds to TTR protein]; Halogenated Diphenyl Ethers analog inhibits the reaction [Thyroxine binds to TTR protein]; PCB 180 inhibits the reaction [Thyroxine binds to TTR protein]; pentabromophenol inhibits the reaction [Thyroxine binds to TTR protein]; Pentachlorophenol inhibits the reaction [Thyroxine binds to TTR protein]; perfluorobutanesulfonic acid affects the reaction [Thyroxine binds to TTR protein]; perfluorobutyric acid affects the reaction [Thyroxine binds to TTR protein]; perfluorodecanoic acid affects the reaction [Thyroxine binds to TTR protein]; perfluorododecanoic acid affects the reaction [Thyroxine binds to TTR protein]; perfluoroheptanoic acid affects the reaction [Thyroxine binds to TTR protein]; perfluorohexanoic acid affects the reaction [Thyroxine binds to TTR protein]; perfluorononanoic acid affects the reaction [Thyroxine binds to TTR protein]; perfluorooctane sulfonic acid affects the reaction [Thyroxine binds to TTR protein]; perfluorooctane sulfonic acid inhibits the reaction [Thyroxine binds to TTR protein]; perfluorooctanoic acid affects the reaction [Thyroxine binds to TTR protein]; perfluorooctanoic acid inhibits the reaction [Thyroxine binds to TTR protein]; perfluoroundecanoic acid affects the reaction [Thyroxine binds to TTR protein]; Polychlorinated Biphenyls analog inhibits the reaction [Thyroxine binds to TTR protein]; T-2 Toxin inhibits the reaction [Thyroxine binds to TTR protein]; tetrabromobisphenol A inhibits the reaction [Thyroxine binds to TTR protein]; tetrachlorodian inhibits the reaction [Thyroxine binds to TTR protein]; Thyroxine inhibits the reaction [1-anilino-8-naphthalenesulfonate binds to TTR protein]; Waste Water inhibits the reaction [Thyroxine binds to TTR protein] 2,2',4,4'-tetrabromodiphenyl ether inhibits the reaction [Thyroxine binds to TTR protein]; 2,2',4,4'-tetrabromodiphenyl ether metabolite inhibits the reaction [Thyroxine binds to TTR protein] |
CTD |
PMID:10631123 PMID:10869457 PMID:16478101 PMID:16601080 PMID:18161906 PMID:20039755 PMID:20804816 PMID:21357386 PMID:21517007 PMID:23584369 PMID:27528273 PMID:29283575 PMID:31077750 PMID:33095664 |
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NCBI chr18:15,532,963...15,542,180
Ensembl chr18:15,532,963...15,540,177
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G |
Ucp2 |
uncoupling protein 2 |
multiple interactions |
EXP |
Thyroxine promotes the reaction [darglitazone results in increased expression of UCP2 mRNA] |
CTD |
PMID:12588052 |
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NCBI chr 1:165,506,375...165,512,744
Ensembl chr 1:165,506,361...165,512,744
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G |
Ugt1a1 |
UDP glucuronosyltransferase family 1 member A1 |
increases expression |
EXP |
Thyroxine results in increased expression of UGT1A1 mRNA |
CTD |
PMID:17884940 |
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NCBI chr 9:95,295,701...95,302,822
Ensembl chr 9:95,161,157...95,302,822
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G |
Ugt1a3 |
UDP glycosyltransferase 1 family, polypeptide A3 |
increases expression |
EXP |
Thyroxine results in increased expression of UGT1A5 mRNA |
CTD |
PMID:17884940 |
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NCBI chr 9:95,274,707...95,302,822
Ensembl chr 9:95,161,157...95,302,822
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G |
Ugt1a7c |
UDP glucuronosyltransferase 1 family, polypeptide A7C |
increases expression |
EXP |
Thyroxine results in increased expression of UGT1A7 mRNA |
CTD |
PMID:17884940 |
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NCBI chr 9:95,233,957...95,302,822
Ensembl chr 9:95,161,157...95,302,822
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G |
Ugt1a9 |
UDP glucuronosyltransferase family 1 member A9 |
multiple interactions |
EXP |
[Clofibrate co-treated with Thyroxine] results in increased activity of UGT1A9 protein |
CTD |
PMID:18219302 |
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NCBI chr 9:95,161,157...95,302,822
Ensembl chr 9:95,161,157...95,302,822
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