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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:poly(vinylpyrrolidone)
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Accession:CHEBI:53248 term browser browse the term
Definition:A vinyl polymer composed of repeating -CH2-CR- units where R is a 2-oxopyrrolidin-1-yl group.
Synonyms:exact_synonym: poly[1-(2-oxopyrrolidin-1-yl)ethylene]
 related_synonym: 1-Ethenyl-2-pyrrolidinone homopolymer;   1-Ethenyl-2-pyrrolidinone polymers;   1-Vinyl-2-pyrrolidinone homopolymer;   1-Vinyl-2-pyrrolidinone polymer;   1-Vinyl-2-pyrrolidone polymer;   Crospovidonum;   Formula=(C6H9NO)n;   N-Vinyl-2-pyrrolidone polymer;   N-Vinylbutyrolactam polymer;   N-Vinylpyrrolidinone polymer;   N-Vinylpyrrolidone polymer;   PVP;   PVPON;   Polividona;   Polividone;   Poly(1-(2-oxo-1-pyrrolidinyl)ethylene);   Poly(1-ethenyl-2-pyrrolidinone);   Poly(1-vinyl-2-pyrrolidinone);   Poly(1-vinyl-2-pyrrolidinone) homopolymer;   Poly(1-vinyl-2-pyrrolidone);   Poly(1-vinylpyrrolidinone);   Poly(N-vinyl-2-pyrrolidinone);   Poly(N-vinyl-2-pyrrolidone);   Poly(N-vinylbutyrolactam);   Poly(N-vinylpyrrolidinone);   Poly-N-vinyl pyrrolidone;   Polyvidonum;   Polyvinylpyrrolidone;   Povidone;   Vinylpyrrolidinone polymer;   Vinylpyrrolidone polymer;   poly(N-vinylpyrrolidone)
 xref: Beilstein:10781921;   Beilstein:8192478;   Beilstein:8473739;   Beilstein:8473925;   CAS:9003-39-8;   Gmelin:1451700;   KEGG:C19509;   KEGG:D02295
 xref_mesh: MESH:D011205
 xref: PMID:12927801;   PMID:15137988;   PMID:16776723;   PMID:8448384;   Reaxys:18634154



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poly(vinylpyrrolidone) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp5g2 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9) multiple interactions ISO [Silver analog co-treated with Povidone] results in decreased expression of ATP5MC2 mRNA CTD PMID:25194297 NCBI chr15:102,662,868...102,671,047
Ensembl chr15:102,662,864...102,672,352
JBrowse link
G Bola3 bolA-like 3 (E. coli) multiple interactions ISO [Silver analog co-treated with Povidone] results in decreased expression of BOLA3 mRNA CTD PMID:25194297 NCBI chr 6:83,349,147...83,360,136
Ensembl chr 6:83,349,147...83,360,136
JBrowse link
G Casp3 caspase 3 multiple interactions ISO [Silver co-treated with Povidone] affects the expression of CASP3 protein; [Silver co-treated with Povidone] results in decreased expression of CASP3 mRNA CTD PMID:27387714 NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) multiple interactions ISO [Silver co-treated with Povidone] results in decreased expression of CDKN1A mRNA; [Silver co-treated with Povidone] results in decreased expression of CDKN1A protein CTD PMID:27387714 NCBI chr17:29,090,979...29,100,722
Ensembl chr17:29,090,976...29,100,727
JBrowse link
G Col8a1 collagen, type VIII, alpha 1 multiple interactions ISO [Silver analog co-treated with Povidone] results in increased expression of COL8A1 mRNA CTD PMID:25194297 NCBI chr16:57,624,256...57,754,737
Ensembl chr16:57,624,258...57,754,737
JBrowse link
G Cox17 cytochrome c oxidase assembly protein 17, copper chaperone multiple interactions ISO [Silver analog co-treated with Povidone] results in decreased expression of COX17 mRNA CTD PMID:25194297 NCBI chr16:38,346,983...38,352,763
Ensembl chr16:38,346,991...38,352,763
Ensembl chr16:38,346,991...38,352,763
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO [Silver analog co-treated with Povidone] results in increased expression of CYP1A1 mRNA CTD PMID:25194297 NCBI chr 9:57,687,928...57,703,824
Ensembl chr 9:57,687,928...57,703,824
JBrowse link
G Dad1 defender against cell death 1 multiple interactions ISO [Silver analog co-treated with Povidone] results in decreased expression of DAD1 mRNA CTD PMID:25194297 NCBI chr14:54,235,485...54,253,929
Ensembl chr14:54,235,479...54,254,104
JBrowse link
G Gbp2 guanylate binding protein 2 multiple interactions ISO [Silver analog co-treated with Povidone] results in decreased expression of GBP2 mRNA CTD PMID:25194297 NCBI chr 3:142,620,663...142,638,008
Ensembl chr 3:142,620,602...142,638,008
JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO [Silver co-treated with Povidone] results in increased expression of H2AX protein modified form CTD PMID:27387714 NCBI chr 9:44,334,715...44,336,077
Ensembl chr 9:44,334,694...44,336,077
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO [Silver analog co-treated with Povidone] results in increased expression of HMOX1 mRNA CTD PMID:25194297 NCBI chr 8:75,093,618...75,100,593
Ensembl chr 8:75,093,621...75,100,589
JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 multiple interactions ISO [Silver analog co-treated with Povidone] results in decreased expression of IFIT3 mRNA CTD PMID:25194297 NCBI chr19:34,583,119...34,588,982
Ensembl chr19:34,583,531...34,588,731
JBrowse link
G Lims1 LIM and senescent cell antigen-like domains 1 multiple interactions ISO [Silver analog co-treated with Povidone] results in increased expression of LIMS1 mRNA CTD PMID:25194297 NCBI chr10:58,323,342...58,424,691
Ensembl chr10:58,323,466...58,424,691
JBrowse link
G Lmnb2 lamin B2 multiple interactions ISO [Silver analog co-treated with Povidone] results in decreased expression of LMNB2 mRNA CTD PMID:25194297 NCBI chr10:80,901,363...80,918,245
Ensembl chr10:80,901,203...80,918,245
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions EXP [Silver Compounds co-treated with Povidone] results in increased activity of MAPK1 protein CTD PMID:21729742 NCBI chr16:16,983,382...17,047,453
Ensembl chr16:16,983,382...17,047,453
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions EXP [Silver Compounds co-treated with Povidone] results in increased activity of MAPK3 protein CTD PMID:21729742 NCBI chr 7:126,759,626...126,765,816
Ensembl chr 7:126,759,601...126,765,819
JBrowse link
G Mdm2 transformed mouse 3T3 cell double minute 2 multiple interactions ISO [Silver co-treated with Povidone] affects the expression of MDM2 protein; [Silver co-treated with Povidone] results in decreased expression of MDM2 mRNA CTD PMID:27387714 NCBI chr10:117,688,875...117,710,758
Ensembl chr10:117,688,875...117,710,758
JBrowse link
G Mt1 metallothionein 1 multiple interactions ISO [Silver analog co-treated with Povidone] affects the expression of MT1A mRNA CTD PMID:25194297 NCBI chr 8:94,178,883...94,180,327
Ensembl chr 8:94,179,082...94,180,327
JBrowse link
G Nfix nuclear factor I/X multiple interactions ISO [Silver analog co-treated with Povidone] results in increased expression of NFIX mRNA CTD PMID:25194297 NCBI chr 8:84,704,712...84,801,238
Ensembl chr 8:84,699,876...84,800,344
JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 multiple interactions ISO [Silver analog co-treated with Povidone] results in increased expression of NQO1 mRNA CTD PMID:25194297 NCBI chr 8:107,388,225...107,403,205
Ensembl chr 8:107,388,225...107,403,206
JBrowse link
G Nrm nurim (nuclear envelope membrane protein) multiple interactions ISO [Silver analog co-treated with Povidone] results in decreased expression of NRM mRNA CTD PMID:25194297 NCBI chr17:35,860,311...35,865,400
Ensembl chr17:35,861,318...35,865,402
JBrowse link
G Nuak2 NUAK family, SNF1-like kinase, 2 multiple interactions ISO [Silver analog co-treated with Povidone] results in decreased expression of NUAK2 mRNA CTD PMID:25194297 NCBI chr 1:132,316,125...132,333,488
Ensembl chr 1:132,316,126...132,333,488
JBrowse link
G Ocln occludin affects expression ISO Povidone affects the expression of OCLN mRNA CTD PMID:19729060 NCBI chr13:100,496,504...100,552,718
Ensembl chr13:100,496,507...100,552,718
JBrowse link
G Prpf38b PRP38 pre-mRNA processing factor 38 (yeast) domain containing B multiple interactions ISO [Silver analog co-treated with Povidone] results in decreased expression of PRPF38B mRNA CTD PMID:25194297 NCBI chr 3:108,902,805...108,911,729
Ensembl chr 3:108,902,805...108,911,727
JBrowse link
G Prr13 proline rich 13 multiple interactions ISO [Silver analog co-treated with Povidone] results in decreased expression of PRR13 mRNA CTD PMID:25194297 NCBI chr15:102,459,170...102,462,806
Ensembl chr15:102,459,028...102,462,806
JBrowse link
G Psenen presenilin enhancer gamma secretase subunit multiple interactions ISO [Silver analog co-treated with Povidone] results in decreased expression of PSENEN mRNA CTD PMID:25194297 NCBI chr 7:30,561,865...30,563,627
Ensembl chr 7:30,561,863...30,563,627
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO [Silver analog co-treated with Povidone] results in increased expression of PTGS2 mRNA CTD PMID:25194297 NCBI chr 1:150,100,031...150,108,234
Ensembl chr 1:150,100,031...150,108,227
JBrowse link
G Ptk2 PTK2 protein tyrosine kinase 2 multiple interactions EXP [Silver Compounds co-treated with Povidone] results in increased activity of PTK2 protein CTD PMID:21729742 NCBI chr15:73,205,102...73,423,820
Ensembl chr15:73,205,102...73,423,280
JBrowse link
G Rab14 RAB14, member RAS oncogene family multiple interactions ISO [Silver analog co-treated with Povidone] results in increased expression of RAB14 mRNA CTD PMID:25194297 NCBI chr 2:35,180,205...35,201,120
Ensembl chr 2:35,180,205...35,201,120
JBrowse link
G Samd9l sterile alpha motif domain containing 9-like multiple interactions ISO [Silver analog co-treated with Povidone] results in decreased expression of SAMD9L mRNA CTD PMID:25194297 NCBI chr 6:3,372,257...3,399,571
Ensembl chr 6:3,372,257...3,399,572
JBrowse link
G Selenow selenoprotein W multiple interactions ISO [Silver analog co-treated with Povidone] results in decreased expression of SELENOW mRNA CTD PMID:25194297 NCBI chr 7:15,917,208...15,922,371
Ensembl chr 7:15,917,208...15,922,402
JBrowse link
G Slc5a3 solute carrier family 5 (inositol transporters), member 3 multiple interactions ISO [Silver analog co-treated with Povidone] results in increased expression of SLC5A3 mRNA CTD PMID:25194297 NCBI chr16:92,058,322...92,087,473
Ensembl chr16:92,058,322...92,087,473
JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial multiple interactions ISO [Silver co-treated with Povidone] results in increased expression of SOD2 mRNA; [Silver co-treated with Povidone] results in increased expression of SOD2 protein CTD PMID:27387714 NCBI chr17:13,007,839...13,018,119
Ensembl chr17:13,006,846...13,040,063
JBrowse link
G Sparc secreted acidic cysteine rich glycoprotein multiple interactions ISO [Silver analog co-treated with Povidone] results in decreased expression of SPARC mRNA CTD PMID:25194297 NCBI chr11:55,394,159...55,420,080
Ensembl chr11:55,394,500...55,423,183
JBrowse link
G Stat2 signal transducer and activator of transcription 2 multiple interactions ISO [Silver analog co-treated with Povidone] results in decreased expression of STAT2 mRNA CTD PMID:25194297 NCBI chr10:128,270,498...128,292,853
Ensembl chr10:128,270,559...128,292,849
JBrowse link
G Sv2b synaptic vesicle glycoprotein 2 b multiple interactions ISO [Silver analog co-treated with Povidone] results in increased expression of SV2B mRNA CTD PMID:25194297 NCBI chr 7:75,114,894...75,309,262
Ensembl chr 7:75,114,894...75,309,262
JBrowse link
G Tiparp TCDD-inducible poly(ADP-ribose) polymerase multiple interactions ISO [Silver analog co-treated with Povidone] results in increased expression of TIPARP mRNA CTD PMID:25194297 NCBI chr 3:65,528,447...65,555,518
Ensembl chr 3:65,528,410...65,555,518
JBrowse link
G Tmtc3 transmembrane and tetratricopeptide repeat containing 3 multiple interactions ISO [Silver analog co-treated with Povidone] results in increased expression of TMTC3 mRNA CTD PMID:25194297 NCBI chr10:100,443,902...100,487,365
Ensembl chr10:100,443,902...100,487,350
JBrowse link
G Trappc1 trafficking protein particle complex 1 multiple interactions ISO [Silver analog co-treated with Povidone] results in decreased expression of TRAPPC1 mRNA CTD PMID:25194297 NCBI chr11:69,323,986...69,325,793
Ensembl chr11:69,323,980...69,325,793
JBrowse link
G Trp53 transformation related protein 53 multiple interactions ISO [Silver co-treated with Povidone] affects the phosphorylation of TP53 protein; [Silver co-treated with Povidone] results in decreased expression of TP53 mRNA; [Silver co-treated with Povidone] results in decreased expression of TP53 protein CTD PMID:27387714 NCBI chr11:69,580,348...69,591,873
Ensembl chr11:69,580,359...69,591,873
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions EXP [Silver Compounds co-treated with Povidone] results in increased expression of VEGFA protein CTD PMID:21729742 NCBI chr17:46,016,993...46,032,377
Ensembl chr17:46,016,993...46,032,369
JBrowse link
G Wdfy1 WD repeat and FYVE domain containing 1 multiple interactions ISO [Silver analog co-treated with Povidone] results in increased expression of WDFY1 mRNA CTD PMID:25194297 NCBI chr 1:79,702,262...79,776,143
Ensembl chr 1:79,702,262...79,776,143
JBrowse link
G Zfhx3 zinc finger homeobox 3 multiple interactions ISO [Silver analog co-treated with Povidone] results in increased expression of ZFHX3 mRNA CTD PMID:25194297 NCBI chr 8:108,279,311...108,961,636
Ensembl chr 8:107,942,644...108,961,630
JBrowse link

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  CHEBI ontology 21797
    role 21776
      application 21291
        pharmaceutical 20759
          blood substitute 52
            poly(vinylpyrrolidone) 43
              poly(vinylpyrrolidone)-coated Ag nanoparticle + 0
Path 2
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  CHEBI ontology 21797
    subatomic particle 21783
      composite particle 21783
        hadron 21783
          baryon 21783
            nucleon 21783
              atomic nucleus 21783
                atom 21783
                  group 21677
                    polyatomic entity 21677
                      macromolecule 3820
                        homopolymer macromolecule 104
                          poly(alkylene) macromolecule 74
                            polyethylene macromolecule 74
                              vinyl polymer macromolecule 57
                                poly(vinylpyrrolidone) 43
                                  poly(vinylpyrrolidone)-coated Ag nanoparticle + 0
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