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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:vinyl polymer macromolecule
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Accession:CHEBI:53242 term browser browse the term
Definition:A macromolecule composed of repeating -CHR-CH2- units.
Synonyms:related_synonym: vinyl polymer;   vinyl polymers


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colesevelam hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crp C-reactive protein decreases expression ISO Colesevelam Hydrochloride results in decreased expression of CRP protein CTD PMID:16616026 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions
increases expression
ISO Colesevelam Hydrochloride promotes the reaction [Simvastatin results in increased expression of HMGCR mRNA]
Colesevelam Hydrochloride results in increased expression of HMGCR mRNA
CTD PMID:22120639 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Ldlr low density lipoprotein receptor increases expression ISO Colesevelam Hydrochloride results in increased expression of LDLR mRNA CTD PMID:22120639 NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903
JBrowse link
poly(styrene) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 increases expression ISO styrofoam analog results in increased expression of C3 protein CTD PMID:19428933 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G C5 complement C5 increases expression ISO styrofoam analog results in increased expression of C5 protein CTD PMID:19428933 NCBI chr 3:14,049,993...14,113,931
NCBI chr 3:14,206,466...14,229,141
Ensembl chr 3:14,049,995...14,229,080
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
affects activity
ISO styrofoam analog promotes the reaction [Cimetidine results in decreased activity of CYP1A2 protein]
styrofoam analog affects the activity of CYP1A2 protein
CTD PMID:19909766 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases activity
multiple interactions
ISO styrofoam analog results in decreased activity of CYP2D6 protein
styrofoam analog promotes the reaction [Cimetidine results in decreased activity of CYP2D6 protein]
CTD PMID:19909766 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 decreases activity
multiple interactions
ISO styrofoam analog results in decreased activity of CYP3A4 protein
styrofoam analog promotes the reaction [Cimetidine results in decreased activity of CYP3A4 protein]
CTD PMID:19909766 NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397
JBrowse link
G Itgam integrin subunit alpha M increases expression ISO styrofoam analog results in increased expression of ITGAM protein CTD PMID:19428933 NCBI chr 1:199,495,312...199,545,738
Ensembl chr 1:199,495,298...199,623,960
JBrowse link
G Pf4 platelet factor 4 increases secretion ISO styrofoam analog results in increased secretion of PF4 protein CTD PMID:19428933 NCBI chr14:18,848,549...18,849,258
Ensembl chr14:18,848,549...18,849,258
JBrowse link
G Ppbp pro-platelet basic protein increases secretion ISO styrofoam analog results in increased secretion of PPBP protein CTD PMID:19428933 NCBI chr14:18,852,433...18,853,237
Ensembl chr14:18,851,954...18,853,315
JBrowse link
G Selp selectin P increases expression ISO styrofoam results in increased expression of SELP protein CTD PMID:21123846 NCBI chr13:82,428,914...82,464,629
Ensembl chr13:82,429,063...82,464,628
JBrowse link
poly(vinyl chloride) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angpt1 angiopoietin 1 decreases expression ISO Polyvinyl Chloride results in decreased expression of ANGPT1 mRNA CTD PMID:12809767 NCBI chr 7:81,338,327...81,592,459
Ensembl chr 7:81,342,280...81,592,206
JBrowse link
poly(vinylpyrrolidone) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp5mc2 ATP synthase membrane subunit c locus 2 multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of ATP5MC2 mRNA CTD PMID:25194297 NCBI chr 7:144,264,207...144,272,578
Ensembl chr 7:144,264,199...144,272,578
JBrowse link
G Bola3 bolA family member 3 multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of BOLA3 mRNA CTD PMID:25194297 NCBI chr 4:115,046,693...115,056,140
Ensembl chr 4:115,046,693...115,056,140
JBrowse link
G Casp3 caspase 3 multiple interactions ISO [Silver co-treated with Povidone] affects the expression of CASP3 protein; [Silver co-treated with Povidone] results in decreased expression of CASP3 mRNA CTD PMID:27387714 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO [Silver co-treated with Povidone] results in decreased expression of CDKN1A mRNA; [Silver co-treated with Povidone] results in decreased expression of CDKN1A protein CTD PMID:27387714 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Col8a1 collagen type VIII alpha 1 chain multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of COL8A1 mRNA CTD PMID:25194297 NCBI chr11:44,877,690...45,006,203
Ensembl chr11:44,877,859...45,007,891
JBrowse link
G Cox17 cytochrome c oxidase copper chaperone COX17 multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of COX17 mRNA CTD PMID:25194297 NCBI chr11:64,962,663...64,968,437
Ensembl chr11:64,962,666...64,968,437
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of CYP1A1 mRNA CTD PMID:25194297 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Dad1 defender against cell death 1 multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of DAD1 mRNA CTD PMID:25194297 NCBI chr15:32,868,136...32,887,933
Ensembl chr15:32,868,087...32,888,095
JBrowse link
G Gbp2 guanylate binding protein 2 multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of GBP2 mRNA CTD PMID:25194297 NCBI chr 2:248,276,795...248,293,784
Ensembl chr 2:248,276,709...248,293,784
JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO [Silver co-treated with Povidone] results in increased expression of H2AX protein modified form CTD PMID:27387714 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of HMOX1 mRNA CTD PMID:25194297 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of IFIT3 mRNA CTD PMID:25194297 NCBI chr 1:252,906,234...252,911,377
Ensembl chr 1:252,906,234...252,911,382
JBrowse link
G Lims1 LIM zinc finger domain containing 1 multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of LIMS1 mRNA CTD PMID:25194297 NCBI chr20:27,895,981...28,004,767
Ensembl chr20:27,954,433...28,002,082
JBrowse link
G Lmnb2 lamin B2 multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of LMNB2 mRNA CTD PMID:25194297 NCBI chr 7:11,657,870...11,676,936
Ensembl chr 7:11,660,934...11,675,472
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO [Silver Compounds co-treated with Povidone] results in increased activity of MAPK1 protein CTD PMID:21729742 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO [Silver Compounds co-treated with Povidone] results in increased activity of MAPK3 protein CTD PMID:21729742 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mdm2 MDM2 proto-oncogene multiple interactions ISO [Silver co-treated with Povidone] affects the expression of MDM2 protein; [Silver co-treated with Povidone] results in decreased expression of MDM2 mRNA CTD PMID:27387714 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Mt1 metallothionein 1 multiple interactions EXP [Silver analog co-treated with Povidone] affects the expression of MT1A mRNA CTD PMID:25194297 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
JBrowse link
G Nfix nuclear factor I X multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of NFIX mRNA CTD PMID:25194297 NCBI chr19:25,818,640...25,914,777
Ensembl chr19:25,821,780...25,914,696
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of NQO1 mRNA CTD PMID:25194297 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nrm nurim multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of NRM mRNA CTD PMID:25194297 NCBI chr20:3,397,834...3,402,264
Ensembl chr20:3,397,834...3,401,315
JBrowse link
G Nuak2 NUAK family kinase 2 multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of NUAK2 mRNA CTD PMID:25194297 NCBI chr13:49,092,306...49,109,055
Ensembl chr13:49,092,306...49,109,050
JBrowse link
G Ocln occludin affects expression ISO Povidone affects the expression of OCLN mRNA CTD PMID:19729060 NCBI chr 2:30,527,327...30,577,218
Ensembl chr 2:30,527,715...30,577,218
JBrowse link
G Prpf38b pre-mRNA processing factor 38B multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of PRPF38B mRNA CTD PMID:25194297 NCBI chr 2:211,706,245...211,715,271
Ensembl chr 2:211,706,228...211,715,311
JBrowse link
G Prr13 proline rich 13 multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of PRR13 mRNA CTD PMID:25194297 NCBI chr 7:144,064,931...144,068,235
Ensembl chr 7:144,064,931...144,098,101
JBrowse link
G Psenen presenilin enhancer gamma secretase subunit multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of PSENEN mRNA CTD PMID:25194297 NCBI chr 1:89,016,093...89,017,449
Ensembl chr 1:89,016,096...89,017,290
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of PTGS2 mRNA CTD PMID:25194297 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ptk2 protein tyrosine kinase 2 multiple interactions ISO [Silver Compounds co-treated with Povidone] results in increased activity of PTK2 protein CTD PMID:21729742 NCBI chr 7:114,436,419...114,611,317
Ensembl chr 7:114,437,361...114,590,119
JBrowse link
G Rab14 RAB14, member RAS oncogene family multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of RAB14 mRNA CTD PMID:25194297 NCBI chr 3:14,373,270...14,395,357
Ensembl chr 3:14,373,275...14,395,362
JBrowse link
G Rbm25l1 RNA binding motif protein 25-like 1 multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of RBM25L1 mRNA CTD PMID:25194297 NCBI chr10:10,457,316...10,460,540
Ensembl chr10:10,457,320...10,460,756
JBrowse link
G Selenow selenoprotein W multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of SELENOW mRNA CTD PMID:25194297 NCBI chr 1:77,530,692...77,535,765
Ensembl chr 1:77,533,148...77,535,681
Ensembl chr 1:77,533,148...77,535,681
JBrowse link
G Slc5a3 solute carrier family 5 member 3 multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of SLC5A3 mRNA CTD PMID:25194297 NCBI chr11:32,229,366...32,231,812 JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO [Silver co-treated with Povidone] results in increased expression of SOD2 mRNA; [Silver co-treated with Povidone] results in increased expression of SOD2 protein CTD PMID:27387714 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sparc secreted protein acidic and cysteine rich multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of SPARC mRNA CTD PMID:25194297 NCBI chr10:40,742,390...40,764,232
Ensembl chr10:40,742,400...40,764,185
JBrowse link
G Stat2 signal transducer and activator of transcription 2 multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of STAT2 mRNA CTD PMID:25194297 NCBI chr 7:2,691,064...2,707,530
Ensembl chr 7:2,691,369...2,707,741
JBrowse link
G Sv2b synaptic vesicle glycoprotein 2b multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of SV2B mRNA CTD PMID:25194297 NCBI chr 1:136,664,199...136,842,247
Ensembl chr 1:136,664,204...136,842,247
JBrowse link
G Tiparp TCDD-inducible poly(ADP-ribose) polymerase multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of TIPARP mRNA CTD PMID:25194297 NCBI chr 2:157,316,293...157,342,979
Ensembl chr 2:157,316,266...157,341,469
JBrowse link
G Tmtc3 transmembrane O-mannosyltransferase targeting cadherins 3 multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of TMTC3 mRNA CTD PMID:25194297 NCBI chr 7:40,171,957...40,217,056
Ensembl chr 7:40,171,963...40,217,056
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO [Silver co-treated with Povidone] affects the phosphorylation of TP53 protein; [Silver co-treated with Povidone] results in decreased expression of TP53 mRNA; [Silver co-treated with Povidone] results in decreased expression of TP53 protein CTD PMID:27387714 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Trappc1 trafficking protein particle complex subunit 1 multiple interactions EXP [Silver analog co-treated with Povidone] results in decreased expression of TRAPPC1 mRNA CTD PMID:25194297 NCBI chr10:55,924,996...55,926,582
Ensembl chr10:55,924,938...55,926,783
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO [Silver Compounds co-treated with Povidone] results in increased expression of VEGFA protein CTD PMID:21729742 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Wdfy1 WD repeat and FYVE domain containing 1 multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of WDFY1 mRNA CTD PMID:25194297 NCBI chr 9:85,477,070...85,528,885
Ensembl chr 9:85,475,841...85,528,869
JBrowse link
G Zfhx3 zinc finger homeobox 3 multiple interactions EXP [Silver analog co-treated with Povidone] results in increased expression of ZFHX3 mRNA CTD PMID:25194297 NCBI chr19:42,753,983...42,925,794
Ensembl chr19:42,758,127...42,920,344
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19883
    chemical entity 19883
      molecular entity 19880
        polyatomic entity 19794
          macromolecule 3476
            homopolymer macromolecule 103
              poly(alkylene) macromolecule 73
                polyethylene macromolecule 73
                  vinyl polymer macromolecule 56
                    colesevelam + 3
                    colesevelam hydrochloride 3
                    poly(4-vinylbenzoic acid) 0
                    poly(N-vinylimidazole) macromolecule + 0
                    poly(acrylonitrile) macromolecule + 0
                    poly(allylamine hydrochloride) 0
                    poly(ethylethylene) 0
                    poly(vinyl acetate) 0
                    poly(vinyl alcohol) macromolecule + 0
                    poly(vinyl benzoate) 0
                    poly(vinyl butyral) macromolecule + 0
                    poly(vinyl chloride) 1
                    poly(vinyl fluoride) 0
                    poly(vinyl methyl ether) macromolecule + 0
                    poly(vinyl sulfate) 0
                    poly(vinylcarbazole) macromolecule + 0
                    poly(vinylpyridine) + 0
                    poly(vinylpyrrolidone) + 43
                    poly(vinyltriphenylamine) 0
                    polyanethol sulfonic acid macromolecule + 0
                    polystyrene macromolecule + 9
                    vinyl polymer + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19883
    subatomic particle 19881
      composite particle 19881
        hadron 19881
          baryon 19881
            nucleon 19881
              atomic nucleus 19881
                atom 19881
                  group 19795
                    polyatomic entity 19794
                      macromolecule 3476
                        homopolymer macromolecule 103
                          poly(alkylene) macromolecule 73
                            polyethylene macromolecule 73
                              vinyl polymer macromolecule 56
                                colesevelam + 3
                                colesevelam hydrochloride 3
                                poly(4-vinylbenzoic acid) 0
                                poly(N-vinylimidazole) macromolecule + 0
                                poly(acrylonitrile) macromolecule + 0
                                poly(allylamine hydrochloride) 0
                                poly(ethylethylene) 0
                                poly(vinyl acetate) 0
                                poly(vinyl alcohol) macromolecule + 0
                                poly(vinyl benzoate) 0
                                poly(vinyl butyral) macromolecule + 0
                                poly(vinyl chloride) 1
                                poly(vinyl fluoride) 0
                                poly(vinyl methyl ether) macromolecule + 0
                                poly(vinyl sulfate) 0
                                poly(vinylcarbazole) macromolecule + 0
                                poly(vinylpyridine) + 0
                                poly(vinylpyrrolidone) + 43
                                poly(vinyltriphenylamine) 0
                                polyanethol sulfonic acid macromolecule + 0
                                polystyrene macromolecule + 9
                                vinyl polymer + 0
paths to the root