Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide
go back to main search page
Accession:CHEBI:53233 term browser browse the term
Definition:The bromide salt of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium.
Synonyms:related_synonym: 2-(4,5-dimethyl-1,3-thiazol-2-yl)-3,5-diphenyl-2H-tetrazol-3-ium bromide;   3-(4,5-Dimethylthiazolyl)-2,5-diphenyltetrazolium bromide;   3-(4,5-Dimethylthiazolyl-2)-2,5-diphenyltetrazolium bromide;   3-(4,5-dimethylthiazole-2-yl)-2,5-diphenyltetrazolium bromide;   Formula=C18H16BrN5S;   InChI=1S/C18H16N5S.BrH/c1-13-14(2)24-18(19-13)23-21-17(15-9-5-3-6-10-15)20-22(23)16-11-7-4-8-12-16;/h3-12H,1-2H3;1H/q+1;/p-1;   InChIKey=AZKSAVLVSZKNRD-UHFFFAOYSA-M;   MMT Tetrazolium;   MTT;   Methylthiazoletetrazolium;   SMILES=[Br-].Cc1nc(sc1C)-[n+]1nc(nn1-c1ccccc1)-c1ccccc1;   TMCHB;   Thiazolyl Blue Monotetrazolium;   Thiazolyl blue;   Thiazolyl blue tetrazolium bromide
 xref: Beilstein:3825277;   CAS:298-93-1
 xref_mesh: MESH:C022616
 xref: PMID:11164558;   PMID:11479950;   PMID:14693038;   PMID:23262421;   PMID:23266052;   PMID:23275136;   PMID:23296098;   PMID:23379693;   PMID:23388083;   PMID:23399301;   PMID:23416182;   PMID:23465060;   PMID:23468003;   PMID:23531555;   PMID:23543357;   PMID:23578702;   PMID:23656417;   PMID:23660215;   PMID:7538090;   PMID:7994925;   PMID:9895235



show annotations for term's descendants           Sort by:
3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A decreases activity ISO thiazolyl blue results in decreased activity of ABCB1 protein CTD PMID:15451006 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Aco2 aconitase 2 multiple interactions ISO [Calcium results in increased activity of ACO2 protein] which results in increased reduction of thiazolyl blue; [Potassium deficiency results in decreased activity of ACO2 protein] which results in decreased reduction of thiazolyl blue CTD PMID:12548706 NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261
JBrowse link
G Casp3 caspase 3 increases activity ISO thiazolyl blue results in increased activity of CASP3 protein CTD PMID:22401948 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 increases activity ISO thiazolyl blue results in increased activity of CASP8 protein CTD PMID:22401948 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Nqo2 N-ribosyldihydronicotinamide:quinone dehydrogenase 2 increases reduction
multiple interactions
ISO NQO2 protein results in increased reduction of thiazolyl blue
resveratrol inhibits the reaction [NQO2 protein results in increased reduction of thiazolyl blue]; Tacrine inhibits the reaction [NQO2 protein results in increased reduction of thiazolyl blue]
CTD PMID:29281794 NCBI chr17:30,909,482...30,938,725
Ensembl chr17:30,909,187...30,938,320
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19904
    role 19880
      application 19715
        dye 2971
          3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19904
    subatomic particle 19902
      composite particle 19902
        hadron 19902
          baryon 19902
            nucleon 19902
              atomic nucleus 19902
                atom 19902
                  main group element atom 19852
                    p-block element atom 19852
                      carbon group element atom 19797
                        carbon atom 19792
                          organic molecular entity 19792
                            organic molecule 19746
                              organic cyclic compound 19551
                                organic heterocyclic compound 18894
                                  heteroarene 17161
                                    monocyclic heteroarene 14888
                                      azole 14391
                                        tetrazoles 367
                                          3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium 5
                                            3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide 5
paths to the root