Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide
go back to main search page
Accession:CHEBI:53233 term browser browse the term
Definition:The bromide salt of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium.
Synonyms:related_synonym: 2-(4,5-dimethyl-1,3-thiazol-2-yl)-3,5-diphenyl-2H-tetrazol-3-ium bromide;   3-(4,5-Dimethylthiazolyl)-2,5-diphenyltetrazolium bromide;   3-(4,5-Dimethylthiazolyl-2)-2,5-diphenyltetrazolium bromide;   3-(4,5-dimethylthiazole-2-yl)-2,5-diphenyltetrazolium bromide;   Formula=C18H16BrN5S;   InChI=1S/C18H16N5S.BrH/c1-13-14(2)24-18(19-13)23-21-17(15-9-5-3-6-10-15)20-22(23)16-11-7-4-8-12-16;/h3-12H,1-2H3;1H/q+1;/p-1;   InChIKey=AZKSAVLVSZKNRD-UHFFFAOYSA-M;   MMT Tetrazolium;   MTT;   Methylthiazoletetrazolium;   SMILES=[Br-].Cc1nc(sc1C)-[n+]1nc(nn1-c1ccccc1)-c1ccccc1;   TMCHB;   Thiazolyl Blue Monotetrazolium;   Thiazolyl blue;   Thiazolyl blue tetrazolium bromide
 xref: Beilstein:3825277;   CAS:298-93-1
 xref_mesh: MESH:C022616
 xref: PMID:11164558;   PMID:11479950;   PMID:14693038;   PMID:23262421;   PMID:23266052;   PMID:23275136;   PMID:23296098;   PMID:23379693;   PMID:23388083;   PMID:23399301;   PMID:23416182;   PMID:23465060;   PMID:23468003;   PMID:23531555;   PMID:23543357;   PMID:23578702;   PMID:23656417;   PMID:23660215;   PMID:7538090;   PMID:7994925;   PMID:9895235


show annotations for term's descendants           Sort by:
 
3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A decreases activity ISO thiazolyl blue results in decreased activity of ABCB1 protein CTD PMID:15451006 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Aco2 aconitase 2 multiple interactions ISO [Calcium results in increased activity of ACO2 protein] which results in increased reduction of thiazolyl blue; [Potassium deficiency results in decreased activity of ACO2 protein] which results in decreased reduction of thiazolyl blue CTD PMID:12548706 NCBI chr 7:123,102,493...123,145,608
Ensembl chr 7:123,102,468...123,145,635
JBrowse link
G Casp3 caspase 3 increases activity ISO thiazolyl blue results in increased activity of CASP3 protein CTD PMID:22401948 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 increases activity ISO thiazolyl blue results in increased activity of CASP8 protein CTD PMID:22401948 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Nqo2 N-ribosyldihydronicotinamide:quinone reductase 2 increases reduction
multiple interactions
ISO NQO2 protein results in increased reduction of thiazolyl blue
resveratrol inhibits the reaction [NQO2 protein results in increased reduction of thiazolyl blue]; Tacrine inhibits the reaction [NQO2 protein results in increased reduction of thiazolyl blue]
CTD PMID:29281794 NCBI chr17:32,131,847...32,158,559
Ensembl chr17:32,132,347...32,158,538
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19883
    role 19833
      application 19505
        dye 1307
          3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19883
    subatomic particle 19881
      composite particle 19881
        hadron 19881
          baryon 19881
            nucleon 19881
              atomic nucleus 19881
                atom 19881
                  main group element atom 19771
                    p-block element atom 19771
                      carbon group element atom 19679
                        carbon atom 19668
                          organic molecular entity 19668
                            organic molecule 19596
                              organic cyclic compound 19407
                                organic heterocyclic compound 18517
                                  heteroarene 16558
                                    monocyclic heteroarene 13374
                                      azole 12545
                                        tetrazoles 342
                                          3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium 5
                                            3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide 5
paths to the root