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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:pristane
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Accession:CHEBI:53181 term browser browse the term
Definition:A norterpene that is an acyclic saturated hydrocarbon derived from phytane by loss of its C-16 terminal methyl group.
Synonyms:exact_synonym: 2,6,10,14-tetramethylpentadecane
 related_synonym: Bute hydrocarbon;   Formula=C19H40;   InChI=1S/C19H40/c1-16(2)10-7-12-18(5)14-9-15-19(6)13-8-11-17(3)4/h16-19H,7-15H2,1-6H3;   InChIKey=XOJVVFBFDXDTEG-UHFFFAOYSA-N;   Norphytan;   Norphytane;   Pristan;   SMILES=CC(C)CCCC(C)CCCC(C)CCCC(C)C
 alt_id: CHEBI:77511
 xref: Beilstein:1720538;   CAS:1921-70-6
 xref_mesh: MESH:C009042
 xref: MetaCyc:CPD-15252;   PMID:21725847;   PMID:22076633;   PMID:22160928;   PMID:22391806;   PMID:22422888;   PMID:22678902;   PMID:22702720;   PMID:22917079;   PMID:22933628;   PMID:23249408;   PMID:23342358;   PMID:23450347;   PMID:9574571;   Reaxys:1720538;   Wikipedia:Pristane


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pristane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctsd cathepsin D increases expression
multiple interactions		 EXP pristane results in increased expression of CTSD protein
[pristane co-treated with Cromolyn Sodium] results in increased expression of CTSD protein		 CTD PMID:8812242 NCBI chr 7:141,929,647...141,941,564
Ensembl chr 7:141,929,648...141,941,775 		JBrowse link
G Ifnb1 interferon beta 1, fibroblast multiple interactions
increases expression		 ISO MIR26A mRNA inhibits the reaction [pristane results in increased expression of IFNB1 mRNA] CTD PMID:24423102 NCBI chr 4:88,440,253...88,441,083
Ensembl chr 4:88,440,262...88,441,011 		JBrowse link
G Il12a interleukin 12a affects response to substance EXP IL12A protein affects the susceptibility to pristane CTD PMID:12911539 NCBI chr 3:68,597,977...68,605,881
Ensembl chr 3:68,597,977...68,605,880 		JBrowse link
G Mir26a-1 microRNA 26a-1 affects expression
multiple interactions		 ISO pristane affects the expression of MIR26A mRNA
Methotrexate inhibits the reaction [pristane results in decreased expression of MIR26A mRNA]; MIR26A mRNA inhibits the reaction [pristane results in increased expression of IFNB1 mRNA]; MIR26A mRNA inhibits the reaction [pristane results in increased expression of TLR3 mRNA]; MIR26A mRNA inhibits the reaction [pristane results in increased expression of TLR3 protein]; MIR26A mRNA inhibits the reaction [pristane results in increased expression of TNF mRNA]; MIR26A mRNA inhibits the reaction [pristane results in increased expression of TNF protein]		 CTD PMID:24423102 NCBI chr 9:118,860,864...118,860,953
Ensembl chr 9:118,860,864...118,860,953 		JBrowse link
G Nos2 nitric oxide synthase 2, inducible increases expression EXP pristane results in increased expression of NOS2 mRNA CTD PMID:15075356 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080 		JBrowse link
G Ogg1 8-oxoguanine DNA-glycosylase 1 increases response to substance EXP OGG1 gene mutant form results in increased susceptibility to pristane CTD PMID:33072095 NCBI chr 6:113,303,959...113,311,149
Ensembl chr 6:113,303,933...113,312,029 		JBrowse link
G Ptger1 prostaglandin E receptor 1 (subtype EP1) increases expression EXP pristane results in increased expression of PTGER1 mRNA CTD PMID:15075356 NCBI chr 8:84,393,171...84,399,385
Ensembl chr 8:84,393,307...84,399,382 		JBrowse link
G Ptger3 prostaglandin E receptor 3 (subtype EP3) increases expression EXP pristane results in increased expression of PTGER3 mRNA CTD PMID:15075356 NCBI chr 3:157,272,459...157,350,392
Ensembl chr 3:157,272,529...157,351,525 		JBrowse link
G Ptger4 prostaglandin E receptor 4 (subtype EP4) increases expression EXP pristane results in increased expression of PTGER4 mRNA CTD PMID:15075356 NCBI chr15:5,262,880...5,273,668
Ensembl chr15:5,236,142...5,273,668 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression EXP pristane results in increased expression of PTGS2 mRNA CTD PMID:15075356 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978 		JBrowse link
G Tlr3 toll-like receptor 3 multiple interactions
increases expression		 ISO Methotrexate inhibits the reaction [pristane results in increased expression of TLR3 mRNA]; MIR26A mRNA inhibits the reaction [pristane results in increased expression of TLR3 mRNA]; MIR26A mRNA inhibits the reaction [pristane results in increased expression of TLR3 protein]
pristane results in increased expression of TLR3 mRNA; pristane results in increased expression of TLR3 protein		 CTD PMID:24423102 NCBI chr 8:45,848,702...45,864,112
Ensembl chr 8:45,848,702...45,864,117 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression		 ISO MIR26A mRNA inhibits the reaction [pristane results in increased expression of TNF mRNA]; MIR26A mRNA inhibits the reaction [pristane results in increased expression of TNF protein]
pristane results in increased expression of TNF mRNA; pristane results in increased expression of TNF protein		 CTD PMID:24423102 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22178
    role 22194
      biological role 22162
        immunomodulator 15681
          immunological adjuvant 703
            pristane 12
Path 2
Term Annotations click to browse term
  CHEBI ontology 22178
    subatomic particle 22170
      composite particle 22170
        hadron 22201
          baryon 22170
            nucleon 22170
              atomic nucleus 22170
                atom 22170
                  main group element atom 22104
                    main group molecular entity 22104
                      s-block molecular entity 21729
                        hydrogen molecular entity 21646
                          hydrides 20758
                            organic hydride 20308
                              organic fundamental parent 20308
                                hydrocarbon 19888
                                  alkane 14845
                                    long-chain alkane 626
                                      pristane 12
paths to the root