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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:pristane
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Accession:CHEBI:53181 term browser browse the term
Definition:A norterpene that is an acyclic saturated hydrocarbon derived from phytane by loss of its C-16 terminal methyl group.
Synonyms:exact_synonym: 2,6,10,14-tetramethylpentadecane
 related_synonym: Bute hydrocarbon;   Formula=C19H40;   InChI=1S/C19H40/c1-16(2)10-7-12-18(5)14-9-15-19(6)13-8-11-17(3)4/h16-19H,7-15H2,1-6H3;   InChIKey=XOJVVFBFDXDTEG-UHFFFAOYSA-N;   Norphytan;   Norphytane;   Pristan;   SMILES=CC(C)CCCC(C)CCCC(C)CCCC(C)C
 alt_id: CHEBI:77511
 xref: Beilstein:1720538;   CAS:1921-70-6
 xref_mesh: MESH:C009042
 xref: MetaCyc:CPD-15252;   PMID:21725847;   PMID:22076633;   PMID:22160928;   PMID:22391806;   PMID:22422888;   PMID:22678902;   PMID:22702720;   PMID:22917079;   PMID:22933628;   PMID:23249408;   PMID:23342358;   PMID:23450347;   PMID:9574571;   Reaxys:1720538;   Wikipedia:Pristane


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pristane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctsd cathepsin D increases expression
multiple interactions
ISO pristane results in increased expression of CTSD protein
[pristane co-treated with Cromolyn Sodium] results in increased expression of CTSD protein
CTD PMID:8812242 NCBI chr 1:215,541,570...215,553,446
Ensembl chr 1:215,541,542...215,553,451
JBrowse link
G Ifnb1 interferon beta 1 multiple interactions
increases expression
EXP MIR26A mRNA inhibits the reaction [pristane results in increased expression of IFNB1 mRNA] CTD PMID:24423102 NCBI chr 5:106,865,192...106,865,746
Ensembl chr 5:106,865,192...106,865,746
JBrowse link
G Il12a interleukin 12A affects response to substance ISO IL12A protein affects the susceptibility to pristane CTD PMID:12911539 NCBI chr 2:165,076,945...165,083,996
Ensembl chr 2:165,076,607...165,084,318
JBrowse link
G Mir26a microRNA 26a multiple interactions
affects expression
EXP Methotrexate inhibits the reaction [pristane results in decreased expression of MIR26A mRNA]; MIR26A mRNA inhibits the reaction [pristane results in increased expression of IFNB1 mRNA]; MIR26A mRNA inhibits the reaction [pristane results in increased expression of TLR3 mRNA]; MIR26A mRNA inhibits the reaction [pristane results in increased expression of TLR3 protein]; MIR26A mRNA inhibits the reaction [pristane results in increased expression of TNF mRNA]; MIR26A mRNA inhibits the reaction [pristane results in increased expression of TNF protein]
pristane affects the expression of MIR26A mRNA
CTD PMID:24423102 NCBI chr 8:127,714,441...127,714,530
Ensembl chr 8:127,714,441...127,714,530
JBrowse link
G Nos2 nitric oxide synthase 2 increases expression ISO pristane results in increased expression of NOS2 mRNA CTD PMID:15075356 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase increases response to substance ISO OGG1 gene mutant form results in increased susceptibility to pristane CTD PMID:33072095 NCBI chr 4:145,282,828...145,289,367
Ensembl chr 4:145,282,797...145,289,326
JBrowse link
G Ptger1 prostaglandin E receptor 1 increases expression ISO pristane results in increased expression of PTGER1 mRNA CTD PMID:15075356 NCBI chr19:24,799,422...24,803,373
Ensembl chr19:24,800,072...24,803,373
JBrowse link
G Ptger3 prostaglandin E receptor 3 increases expression ISO pristane results in increased expression of PTGER3 mRNA CTD PMID:15075356 NCBI chr 2:263,895,093...263,979,682
Ensembl chr 2:263,895,241...263,979,698
JBrowse link
G Ptger4 prostaglandin E receptor 4 increases expression ISO pristane results in increased expression of PTGER4 mRNA CTD PMID:15075356 NCBI chr 2:54,951,625...54,966,470
Ensembl chr 2:54,952,821...54,963,448
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO pristane results in increased expression of PTGS2 mRNA CTD PMID:15075356 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Tlr3 toll-like receptor 3 multiple interactions
increases expression
EXP Methotrexate inhibits the reaction [pristane results in increased expression of TLR3 mRNA]; MIR26A mRNA inhibits the reaction [pristane results in increased expression of TLR3 mRNA]; MIR26A mRNA inhibits the reaction [pristane results in increased expression of TLR3 protein]
pristane results in increased expression of TLR3 mRNA; pristane results in increased expression of TLR3 protein
CTD PMID:24423102 NCBI chr16:50,016,466...50,031,011
Ensembl chr16:50,016,857...50,031,214
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
EXP MIR26A mRNA inhibits the reaction [pristane results in increased expression of TNF mRNA]; MIR26A mRNA inhibits the reaction [pristane results in increased expression of TNF protein]
pristane results in increased expression of TNF mRNA; pristane results in increased expression of TNF protein
CTD PMID:24423102 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19773
    role 19723
      biological role 19723
        immunomodulator 14886
          immunological adjuvant 599
            pristane 12
Path 2
Term Annotations click to browse term
  CHEBI ontology 19773
    subatomic particle 19771
      composite particle 19771
        hadron 19771
          baryon 19771
            nucleon 19771
              atomic nucleus 19771
                atom 19771
                  main group element atom 19665
                    main group molecular entity 19665
                      s-block molecular entity 19430
                        hydrogen molecular entity 19424
                          hydrides 18758
                            organic hydride 18356
                              organic fundamental parent 18356
                                hydrocarbon 18076
                                  alkane 13715
                                    long-chain alkane 436
                                      pristane 12
paths to the root