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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:2,4-dinitrobenzenesulfonic acid
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Accession:CHEBI:53070 term browser browse the term
Definition:The arenesulfonic acid that is benzenesulfonic acid with two nitro substituents in the 2- and 4-positions.
Synonyms:related_synonym: 2,4-DNBSA;   2,4-Dinitrobenzenesulphonic acid;   2,4-dinitrobenzene sulfonic acid;   2,4-dinitrobenzene sulphonic acid;   2,4-dinitrobenzene-1-sulfonic acid;   2,4-dinitrobenzene-1-sulphonic acid;   DNBA;   DNBS;   DNBSA;   Formula=C6H4N2O7S;   InChI=1S/C6H4N2O7S/c9-7(10)4-1-2-6(16(13,14)15)5(3-4)8(11)12/h1-3H,(H,13,14,15);   InChIKey=OVOJUAKDTOOXRF-UHFFFAOYSA-N;   SMILES=OS(=O)(=O)c1ccc(cc1[N+]([O-])=O)[N+]([O-])=O;   dinitrobenzenesulfonic acid
 xref: Beilstein:2147447;   CAS:89-02-1;   Gmelin:5198
 xref_mesh: MESH:C001073
 xref: PMID:11739495;   PMID:15307184;   PMID:20336084;   PMID:20631061;   PMID:21354356;   PMID:21915296;   PMID:22144769;   PMID:23494123;   PMID:23554310;   PMID:7994925;   PMID:8466279;   Reaxys:2147447
 cyclic_relationship: is_conjugate_acid_of CHEBI:53069


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2,4-dinitrobenzenesulfonic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase increases expression EXP 2,4-dinitrobenzenesulfonic acid results in increased expression of ADA mRNA CTD PMID:20860664 NCBI chr 3:160,115,840...160,139,947
Ensembl chr 3:160,115,842...160,139,947
JBrowse link
G Adarb1 adenosine deaminase, RNA-specific, B1 increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of ADARB1 mRNA CTD PMID:30116771 NCBI chr20:11,972,352...12,101,022
Ensembl chr20:11,972,381...12,101,047
JBrowse link
G Adora3 adenosine A3 receptor increases expression EXP 2,4-dinitrobenzenesulfonic acid results in increased expression of ADORA3 mRNA; 2,4-dinitrobenzenesulfonic acid results in increased expression of ADORA3 protein CTD PMID:20860664 NCBI chr 2:208,336,909...208,379,217
Ensembl chr 2:208,373,154...208,376,803
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of ATF3 mRNA CTD PMID:30116771 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Bnip3 BCL2 interacting protein 3 decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of BNIP3 mRNA CTD PMID:30116771 NCBI chr 1:211,248,098...211,265,282
Ensembl chr 1:211,248,098...211,265,282
JBrowse link
G Caly calcyon neuron-specific vesicular protein decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of CALY mRNA CTD PMID:30116771 NCBI chr 1:212,537,851...212,549,040
Ensembl chr 1:212,537,848...212,549,477
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of CCL7 mRNA CTD PMID:30116771 NCBI chr10:69,423,083...69,424,933
Ensembl chr10:69,423,086...69,424,979
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of CCR2 mRNA CTD PMID:30116771
G Cdh4 cadherin 4 decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of CDH4 mRNA CTD PMID:30116771 NCBI chr 3:175,220,520...175,283,144
Ensembl chr 3:175,144,495...175,279,761
JBrowse link
G Ciapin1 cytokine induced apoptosis inhibitor 1 increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of CIAPIN1 mRNA CTD PMID:30116771 NCBI chr19:10,596,923...10,612,414
Ensembl chr19:10,596,960...10,610,049
JBrowse link
G Cnr1 cannabinoid receptor 1 decreases response to substance ISO CNR1 results in decreased susceptibility to 2,4-dinitrobenzenesulfonic acid CTD PMID:15085199 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056
JBrowse link
G Creb1 cAMP responsive element binding protein 1 affects expression ISO 2,4-dinitrobenzenesulfonic acid affects the expression of CREB1 mRNA CTD PMID:20385217 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Crlf1 cytokine receptor-like factor 1 increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of CRLF1 mRNA CTD PMID:30116771 NCBI chr16:20,675,042...20,686,365
Ensembl chr16:20,675,042...20,686,317
JBrowse link
G Ctnna3 catenin alpha 3 decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of CTNNA3 mRNA CTD PMID:30116771 NCBI chr20:25,063,124...26,640,428
Ensembl chr20:26,516,836...26,589,209
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of CXCL1 mRNA CTD PMID:30116771 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
JBrowse link
G Dlc1 DLC1 Rho GTPase activating protein multiple interactions
decreases expression
ISO [2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of DLC1 mRNA
2,4-dinitrobenzenesulfonic acid results in decreased expression of DLC1 mRNA
CTD PMID:30116771 NCBI chr16:58,776,489...59,247,752
Ensembl chr16:59,077,574...59,247,754
JBrowse link
G Faah fatty acid amide hydrolase increases response to substance ISO FAAH results in increased susceptibility to 2,4-dinitrobenzenesulfonic acid CTD PMID:15085199 NCBI chr 5:134,852,899...134,872,095
Ensembl chr 5:134,852,875...134,871,775
JBrowse link
G Faahl fatty-acid amide hydrolase-like increases response to substance ISO FAAH results in increased susceptibility to 2,4-dinitrobenzenesulfonic acid CTD PMID:15085199 NCBI chr 5:134,330,204...134,349,400
Ensembl chr 5:134,331,929...134,348,995
JBrowse link
G Fat4 FAT atypical cadherin 4 decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of FAT4 mRNA CTD PMID:30116771 NCBI chr 2:125,751,818...125,879,398
Ensembl chr 2:125,752,130...125,879,387
JBrowse link
G Fhl2 four and a half LIM domains 2 multiple interactions ISO [2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of FHL2 mRNA CTD PMID:30116771 NCBI chr 9:49,920,611...49,994,906
Ensembl chr 9:49,920,854...49,950,093
JBrowse link
G Fhl3 four and a half LIM domains 3 increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of FHL3 mRNA CTD PMID:30116771 NCBI chr 5:142,688,962...142,696,330
Ensembl chr 5:142,689,026...142,696,383
JBrowse link
G Gcnt2 glucosaminyl (N-acetyl) transferase 2 (I blood group) increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of GCNT2 mRNA CTD PMID:30116771 NCBI chr17:21,634,546...21,677,477
Ensembl chr17:21,634,551...21,739,408
JBrowse link
G Gfap glial fibrillary acidic protein increases expression
multiple interactions
ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of GFAP mRNA
GR 159897 inhibits the reaction [2,4-dinitrobenzenesulfonic acid results in increased expression of GFAP mRNA]
CTD PMID:30116771 NCBI chr10:90,990,762...90,999,435
Ensembl chr10:90,990,762...90,999,506
JBrowse link
G Igf1r insulin-like growth factor 1 receptor decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of IGF1R mRNA CTD PMID:30116771 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Il10ra interleukin 10 receptor subunit alpha increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of IL10RA mRNA CTD PMID:30116771 NCBI chr 8:49,558,062...49,573,891
Ensembl chr 8:49,560,035...49,573,742
JBrowse link
G Il6 interleukin 6 increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of IL6 mRNA CTD PMID:30116771 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Itpk1 inositol-tetrakisphosphate 1-kinase multiple interactions
decreases expression
ISO [2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of ITPK1 mRNA
2,4-dinitrobenzenesulfonic acid results in decreased expression of ITPK1 mRNA
CTD PMID:30116771 NCBI chr 6:126,448,920...126,582,188
Ensembl chr 6:126,450,139...126,582,134
JBrowse link
G Jaml junction adhesion molecule like increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of JAML mRNA CTD PMID:30116771 NCBI chr 8:49,378,644...49,408,894
Ensembl chr 8:49,378,644...49,410,088
JBrowse link
G Kalrn kalirin, RhoGEF kinase increases expression
multiple interactions
ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of KALRN mRNA
[2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of KALRN mRNA
CTD PMID:30116771 NCBI chr11:69,484,293...70,025,682
Ensembl chr11:69,484,293...70,025,633
JBrowse link
G Kcnb2 potassium voltage-gated channel subfamily B member 2 multiple interactions
decreases expression
ISO [2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of KCNB2 mRNA
2,4-dinitrobenzenesulfonic acid results in decreased expression of KCNB2 mRNA
CTD PMID:30116771 NCBI chr 5:2,975,934...3,430,837 JBrowse link
G Lif LIF, interleukin 6 family cytokine increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of LIF mRNA CTD PMID:30116771 NCBI chr14:84,482,652...84,500,574
Ensembl chr14:84,482,674...84,500,642
JBrowse link
G Mfsd6 major facilitator superfamily domain containing 6 decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of MFSD6 mRNA CTD PMID:30116771 NCBI chr 9:53,626,412...53,710,820
Ensembl chr 9:53,626,592...53,710,817
JBrowse link
G Msh2 mutS homolog 2 decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of MSH2 mRNA CTD PMID:30116771 NCBI chr 6:11,215,951...11,274,916
Ensembl chr 6:11,215,963...11,274,932
JBrowse link
G Nfix nuclear factor I X decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of NFIX mRNA CTD PMID:30116771 NCBI chr19:25,818,640...25,914,777
Ensembl chr19:25,821,780...25,914,696
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 affects expression ISO 2,4-dinitrobenzenesulfonic acid affects the expression of NFKB1 mRNA CTD PMID:20385217 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nt5e 5' nucleotidase, ecto multiple interactions
decreases expression
ISO [2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of NT5E mRNA
2,4-dinitrobenzenesulfonic acid results in decreased expression of NT5E mRNA
CTD PMID:30116771 NCBI chr 8:95,969,002...96,012,733
Ensembl chr 8:95,968,652...96,012,696
JBrowse link
G Odc1 ornithine decarboxylase 1 increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of ODC1 mRNA CTD PMID:30116771 NCBI chr 6:42,852,529...42,859,142
Ensembl chr 6:42,852,683...42,859,927
JBrowse link
G Oprk1 opioid receptor, kappa 1 decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of OPRK1 mRNA CTD PMID:30116771 NCBI chr 5:13,742,655...13,760,460
Ensembl chr 5:13,744,658...13,760,305
JBrowse link
G Pde4d phosphodiesterase 4D multiple interactions
decreases expression
ISO [2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of PDE4D mRNA
2,4-dinitrobenzenesulfonic acid results in decreased expression of PDE4D mRNA
CTD PMID:30116771 NCBI chr 2:40,219,999...41,468,551
Ensembl chr 2:40,554,146...41,464,264
JBrowse link
G Pik3c2a phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of PIK3C2A mRNA CTD PMID:30116771 NCBI chr 1:185,210,922...185,326,314
Ensembl chr 1:185,210,922...185,326,314
JBrowse link
G Psmb8 proteasome 20S subunit beta 8 decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of PSMB8 mRNA CTD PMID:30116771 NCBI chr20:3,990,809...3,993,772
Ensembl chr20:3,990,613...3,993,769
JBrowse link
G Ptger4 prostaglandin E receptor 4 decreases expression
multiple interactions
ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of PTGER4 mRNA
[2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of PTGER4 mRNA
CTD PMID:30116771 NCBI chr 2:54,951,625...54,966,470
Ensembl chr 2:54,952,821...54,963,448
JBrowse link
G Rps15a ribosomal protein S15a increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of RPS15A mRNA CTD PMID:30116771 NCBI chr 1:187,759,865...187,766,734
Ensembl chr 1:187,759,480...187,766,709
JBrowse link
G RT1-Ba RT1 class II, locus Ba decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of H2-AA mRNA CTD PMID:30116771 NCBI chr20:4,066,133...4,070,726
Ensembl chr20:4,066,132...4,070,721
JBrowse link
G RT1-S3 RT1 class Ib, locus S3 decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of H2-T23 mRNA CTD PMID:30116771 NCBI chr20:3,176,124...3,180,825
Ensembl chr20:3,176,107...3,179,818
JBrowse link
G Sgcd sarcoglycan, delta decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of SGCD mRNA CTD PMID:30116771 NCBI chr10:32,062,946...32,471,454
Ensembl chr10:32,062,946...32,471,454
JBrowse link
G Slc9a1 solute carrier family 9 member A1 increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of SLC9A1 mRNA CTD PMID:30116771 NCBI chr 5:151,573,122...151,626,360
Ensembl chr 5:151,573,092...151,627,316
JBrowse link
G Tac1 tachykinin, precursor 1 multiple interactions
increases expression
ISO GR 159897 inhibits the reaction [2,4-dinitrobenzenesulfonic acid results in increased expression of TAC1 mRNA] CTD PMID:30116771 NCBI chr 4:33,638,853...33,646,819
Ensembl chr 4:33,638,709...33,646,819
JBrowse link
G Tacr2 tachykinin receptor 2 multiple interactions ISO [2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in decreased expression of TACR2 mRNA CTD PMID:30116771 NCBI chr20:31,892,515...31,905,153
Ensembl chr20:31,892,515...31,905,153
JBrowse link
G Taf1b TATA-box binding protein associated factor, RNA polymerase I subunit B multiple interactions
decreases expression
ISO [2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of TAF1B mRNA
2,4-dinitrobenzenesulfonic acid results in decreased expression of TAF1B mRNA
CTD PMID:30116771 NCBI chr 6:43,644,931...43,722,124
Ensembl chr 6:43,644,830...43,722,113
JBrowse link
G Tapbpl TAP binding protein-like decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of TAPBPL mRNA CTD PMID:30116771 NCBI chr 4:157,735,748...157,743,199
Ensembl chr 4:157,735,748...157,743,199
JBrowse link
G Thbs1 thrombospondin 1 increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of THBS1 mRNA CTD PMID:30116771 NCBI chr 3:109,862,120...109,873,466
Ensembl chr 3:109,862,117...109,873,466
JBrowse link
G Tnf tumor necrosis factor increases expression ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of TNF mRNA CTD PMID:20385217 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Trim62 tripartite motif-containing 62 decreases expression ISO 2,4-dinitrobenzenesulfonic acid results in decreased expression of TRIM62 mRNA CTD PMID:30116771 NCBI chr 5:147,068,725...147,099,024
Ensembl chr 5:147,069,616...147,095,242
JBrowse link
G Vti1a vesicle transport through interaction with t-SNAREs 1A increases expression
multiple interactions
ISO 2,4-dinitrobenzenesulfonic acid results in increased expression of VTI1A mRNA
[2,4-dinitrobenzenesulfonic acid co-treated with GR 159897] results in increased expression of VTI1A mRNA
CTD PMID:30116771 NCBI chr 1:276,310,072...276,508,635
Ensembl chr 1:276,309,927...276,490,602
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19853
    chemical entity 19853
      group 19767
        inorganic group 19202
          sulfo group 5741
            organosulfonic acid 5741
              arenesulfonic acid 672
                2,4-dinitrobenzenesulfonic acid 55
Path 2
Term Annotations click to browse term
  CHEBI ontology 19853
    subatomic particle 19851
      composite particle 19851
        hadron 19851
          baryon 19851
            nucleon 19851
              atomic nucleus 19851
                atom 19851
                  main group element atom 19744
                    p-block element atom 19744
                      chalcogen 19438
                        oxygen atom 19400
                          oxygen molecular entity 19400
                            hydroxides 19123
                              oxoacid 18256
                                chalcogen oxoacid 11493
                                  sulfur oxoacid 11097
                                    sulfonic acid 7345
                                      sulfo group 5741
                                        organosulfonic acid 5741
                                          arenesulfonic acid 672
                                            2,4-dinitrobenzenesulfonic acid 55
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