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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:2,4,6-trinitrobenzenesulfonic acid
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Accession:CHEBI:53063 term browser browse the term
Definition:The arenesulfonic acid that is benzenesulfonic acid with three nitro substituents in the 2-, 4- and 6-positions.
Synonyms:related_synonym: 2,4,6-Trinitrobenzene-1-sulfonic acid;   Formula=C6H3N3O9S;   InChI=1S/C6H3N3O9S/c10-7(11)3-1-4(8(12)13)6(19(16,17)18)5(2-3)9(14)15/h1-2H,(H,16,17,18);   InChIKey=NHJVRSWLHSJWIN-UHFFFAOYSA-N;   Picryl sulfonic acid;   SMILES=OS(=O)(=O)c1c(cc(cc1[N+]([O-])=O)[N+]([O-])=O)[N+]([O-])=O;   TNBS;   Trinitrobenzenesulfonic acid;   picrylsulfonic acid
 xref: Beilstein:572358;   CAS:2508-19-2;   Gmelin:1051138
 xref_mesh: MESH:D014302
 xref: PMID:10771133;   PMID:11033063;   PMID:12631250;   PMID:16675348;   PMID:17979222;   PMID:23246254;   PMID:23275612;   PMID:23307099;   PMID:23353033;   PMID:23434856;   PMID:23537331;   PMID:23558009;   PMID:23658667;   PMID:7843258;   PMID:7994925;   PMID:9326394;   PMID:9540973;   Reaxys:572358;   Wikipedia:2\,4\,6-Trinitrobenzenesulfonic_acid


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2,4,6-trinitrobenzenesulfonic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of ABCB11 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of ABCB11 protein CTD PMID:12044520 NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A decreases expression
multiple interactions
ISO Trinitrobenzenesulfonic Acid results in decreased expression of ABCB1 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of ABCB1 mRNA]
CTD PMID:18200517 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of ABCC2 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of ABCC2 protein CTD PMID:12044520 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Actb actin, beta increases expression
decreases expression
ISO
EXP
Trinitrobenzenesulfonic Acid results in increased expression of ACTB mRNA
Trinitrobenzenesulfonic Acid results in decreased expression of ACTB mRNA
CTD PMID:12163651 PMID:17982090 NCBI chr12:13,715,843...13,718,813
Ensembl chr12:13,715,843...13,718,841
JBrowse link
G Adm2 adrenomedullin 2 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of ADM2 mRNA CTD PMID:21808981 NCBI chr 7:130,296,895...130,298,641
Ensembl chr 7:130,296,897...130,298,644
JBrowse link
G Ager advanced glycosylation end product-specific receptor multiple interactions
increases expression
EXP cinnamic aldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of AGER protein]; dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of AGER protein]; hesperetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of AGER protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of AGER protein] CTD PMID:33412153 PMID:33522063 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Agr2 anterior gradient 2, protein disulphide isomerase family member increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of AGR2 mRNA CTD PMID:17982090 NCBI chr 6:55,465,782...55,487,087
Ensembl chr 6:55,465,782...55,487,714
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO [Tetrachlorodibenzodioxin results in increased activity of AHR protein] which results in decreased susceptibility to Trinitrobenzenesulfonic Acid CTD PMID:21131560 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Ak3 adenylate kinase 3 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of AK3 mRNA CTD PMID:17982090 NCBI chr 1:247,144,486...247,169,690
Ensembl chr 1:247,144,491...247,169,693
JBrowse link
G Akap6 A-kinase anchoring protein 6 multiple interactions
decreases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of AKAP6 mRNA] CTD PMID:18200517 NCBI chr 6:73,553,111...73,991,992
Ensembl chr 6:73,553,210...73,990,534
JBrowse link
G Akap9 A-kinase anchoring protein 9 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of AKAP9 mRNA CTD PMID:17982090 NCBI chr 4:27,195,346...27,331,582
Ensembl chr 4:27,195,346...27,331,582
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of AKR1C2 mRNA CTD PMID:25724174 NCBI chr17:69,388,337...69,435,160
Ensembl chr17:69,388,335...69,404,341
JBrowse link
G Alb albumin increases secretion EXP Trinitrobenzenesulfonic Acid results in increased secretion of ALB protein CTD PMID:23307618 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of ALDH1A3 mRNA CTD PMID:17982090 NCBI chr 1:127,302,920...127,337,828
Ensembl chr 1:127,301,128...127,337,882
JBrowse link
G Alpi alkaline phosphatase, intestinal increases activity
multiple interactions
EXP Trinitrobenzenesulfonic Acid results in increased activity of ALPI protein
Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of ALPI protein]
CTD PMID:15867298 NCBI chr 9:94,197,616...94,201,910
Ensembl chr 9:94,197,618...94,201,084
JBrowse link
G Anxa1 annexin A1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of ANXA1 mRNA CTD PMID:17982090 NCBI chr 1:237,893,983...237,910,002
Ensembl chr 1:237,893,966...237,910,012
JBrowse link
G Anxa8 annexin A8 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of ANXA8 mRNA CTD PMID:17982090 NCBI chr16:10,417,174...10,432,388
Ensembl chr16:10,417,185...10,432,393
JBrowse link
G Apbb1ip amyloid beta precursor protein binding family B member 1 interacting protein increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of APBB1IP mRNA CTD PMID:17982090 NCBI chr17:90,098,953...90,149,192
Ensembl chr17:90,099,025...90,149,894
JBrowse link
G Apob apolipoprotein B decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of APOB mRNA CTD PMID:17982090 NCBI chr 6:33,176,826...33,216,381
Ensembl chr 6:33,176,778...33,224,997
JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of AQP3 mRNA CTD PMID:15140218 NCBI chr 5:57,423,735...57,429,252
Ensembl chr 5:57,423,734...57,429,245
JBrowse link
G Aqp4 aquaporin 4 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of AQP4 mRNA CTD PMID:23537331 NCBI chr18:6,766,009...6,782,757
Ensembl chr18:6,765,945...6,782,996
JBrowse link
G Arfip1 ADP-ribosylation factor interacting protein 1 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of ARFIP1 mRNA CTD PMID:23537331 NCBI chr 2:183,503,250...183,582,798
Ensembl chr 2:183,504,330...183,582,553
JBrowse link
G Arg1 arginase 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of ARG1 mRNA CTD PMID:17982090 NCBI chr 1:21,525,421...21,537,872
Ensembl chr 1:21,525,421...21,537,863
JBrowse link
G Arg2 arginase 2 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of ARG2 mRNA CTD PMID:17982090 NCBI chr 6:102,311,097...102,338,406
Ensembl chr 6:102,311,116...102,338,520
JBrowse link
G Arhgap24 Rho GTPase activating protein 24 multiple interactions
decreases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of ARHGAP24 mRNA] CTD PMID:18200517 NCBI chr14:8,383,211...8,600,526
Ensembl chr14:8,383,214...8,600,512
JBrowse link
G Arhgdib Rho GDP dissociation inhibitor beta multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ARHGDIB mRNA] CTD PMID:18200517 NCBI chr 4:170,913,920...170,932,789
Ensembl chr 4:170,913,923...170,932,618
JBrowse link
G Arl4d ADP-ribosylation factor like GTPase 4D increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of ARL4D mRNA CTD PMID:23537331 NCBI chr10:89,577,556...89,580,368
Ensembl chr10:89,578,212...89,580,368
JBrowse link
G Arrb1 arrestin, beta 1 multiple interactions
increases expression
EXP Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ARRB1 mRNA]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ARRB1 protein]; qingre zaoshi liangxue fang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ARRB1 mRNA]; qingre zaoshi liangxue fang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ARRB1 protein]
Trinitrobenzenesulfonic Acid results in increased expression of ARRB1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of ARRB1 protein
CTD PMID:24637189 NCBI chr 1:164,502,099...164,573,947
Ensembl chr 1:164,502,389...164,593,139
JBrowse link
G Atoh1 atonal bHLH transcription factor 1 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of ATOH1 mRNA CTD PMID:17982090 NCBI chr 4:95,498,003...95,500,098
Ensembl chr 4:95,498,003...95,500,089
JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of ATP2A2 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of ATP2A2 protein CTD PMID:17131044 NCBI chr12:39,553,903...39,603,326
Ensembl chr12:39,553,903...39,603,326
JBrowse link
G Atp4a ATPase H+/K+ transporting subunit alpha increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of ATP4A mRNA CTD PMID:17982090 NCBI chr 1:89,162,700...89,175,504
Ensembl chr 1:89,162,639...89,175,811
JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions
increases expression
EXP Losartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BAK1 mRNA] CTD PMID:15502641 NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260
JBrowse link
G Basp1 brain abundant, membrane attached signal protein 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of BASP1 mRNA CTD PMID:17982090 NCBI chr 2:77,586,424...77,632,626
Ensembl chr 2:77,586,424...77,632,628
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
EXP
ISO
dapagliflozin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BAX protein]; Losartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BAX mRNA]; Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BAX protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BAX protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BAX mRNA]
Trinitrobenzenesulfonic Acid results in increased expression of BAX mRNA; Trinitrobenzenesulfonic Acid results in increased expression of BAX protein
D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of BAX protein]
CTD PMID:15502641 PMID:22427801 PMID:24831514 PMID:31428839 PMID:33412153 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
increases expression
decreases expression
EXP dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of BCL2 protein]; Losartan promotes the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of BCL2 mRNA]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of BCL2 protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BCL2 mRNA]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BCL2 protein]; Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of BCL2 protein]; qingre zaoshi liangxue fang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BCL2 mRNA]; qingre zaoshi liangxue fang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BCL2 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of BCL2 protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of BCL2 mRNA]
Trinitrobenzenesulfonic Acid results in increased expression of BCL2 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of BCL2 protein
Trinitrobenzenesulfonic Acid results in decreased expression of BCL2 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of BCL2 protein
CTD PMID:15502641 PMID:24637189 PMID:24831514 PMID:31428839 PMID:33412153 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2a1 BCL2-related protein A1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of BCL2A1B mRNA CTD PMID:17982090 NCBI chr 8:96,551,424...96,559,527
Ensembl chr 8:96,551,245...96,559,483
JBrowse link
G Bcl2l11 BCL2 like 11 multiple interactions
increases expression
ISO [Trinitrobenzenesulfonic Acid results in increased expression of MAPK9 protein] promotes the reaction [BCL2L11 protein binds to MAPK9 protein]; D-JNKI-1 inhibits the reaction [[Trinitrobenzenesulfonic Acid results in increased expression of MAPK9 protein] promotes the reaction [BCL2L11 protein binds to MAPK9 protein]]; D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of BCL2L11 protein]
Trinitrobenzenesulfonic Acid results in increased expression of BCL2L11 protein
CTD PMID:22427801 NCBI chr 3:120,726,906...120,764,192
Ensembl chr 3:120,726,906...120,764,192
JBrowse link
G Bcl3 BCL3, transcription coactivator multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BCL3 mRNA] CTD PMID:18200517 NCBI chr 1:80,730,758...80,745,273
Ensembl chr 1:80,730,499...80,744,831
JBrowse link
G Becn1 beclin 1 multiple interactions
increases expression
EXP dapagliflozin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BECN1 protein]; Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BECN1 protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BECN1 protein] CTD PMID:30503585 PMID:33412153 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Bglap bone gamma-carboxyglutamate protein decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of BGLAP protein CTD PMID:23747339 NCBI chr 2:187,741,770...187,748,445
Ensembl chr 2:187,741,770...187,742,747
JBrowse link
G Bgn biglycan increases expression
multiple interactions
ISO Trinitrobenzenesulfonic Acid results in increased expression of BGN mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BGN mRNA]
CTD PMID:18200517 NCBI chr  X:157,319,042...157,331,204
Ensembl chr  X:157,319,046...157,331,204
JBrowse link
G Bpnt2 3'(2'), 5'-bisphosphate nucleotidase 2 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of BPNT2 mRNA CTD PMID:17982090 NCBI chr17:90,191,119...90,218,013
Ensembl chr17:90,188,043...90,218,013
Ensembl chr 5:90,188,043...90,218,013
JBrowse link
G C1qb complement C1q B chain multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of C1QB mRNA] CTD PMID:17982090 PMID:18200517 NCBI chr 5:155,246,444...155,251,995
Ensembl chr 5:155,246,447...155,252,003
JBrowse link
G C1qc complement C1q C chain increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of C1QC mRNA CTD PMID:17982090 NCBI chr 5:155,255,013...155,258,631
Ensembl chr 5:155,255,005...155,258,392
JBrowse link
G C3 complement C3 multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of C3 mRNA] CTD PMID:17982090 PMID:18200517 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G C4b complement C4B (Chido blood group) increases expression
multiple interactions
ISO Trinitrobenzenesulfonic Acid results in increased expression of C4B mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of C4B mRNA]
CTD PMID:18200517 NCBI chr20:4,302,344...4,316,752
Ensembl chr20:4,302,344...4,316,715
JBrowse link
G Ca3 carbonic anhydrase 3 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CAR3 mRNA CTD PMID:17982090 NCBI chr 2:88,126,519...88,136,063
Ensembl chr 2:88,126,667...88,135,410
JBrowse link
G Cab39 calcium binding protein 39 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of CAB39 mRNA CTD PMID:12163651 NCBI chr 9:92,834,327...92,895,778
Ensembl chr 9:92,834,357...92,895,778
JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of CACNA1C mRNA; Trinitrobenzenesulfonic Acid results in increased expression of CACNA1C protein CTD PMID:23537331 NCBI chr 4:150,635,808...151,270,790
Ensembl chr 4:150,641,066...150,829,913
JBrowse link
G Cacna1e calcium voltage-gated channel subunit alpha1 E increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of CACNA1E mRNA; Trinitrobenzenesulfonic Acid results in increased expression of CACNA1E protein CTD PMID:23537331 NCBI chr13:71,899,445...72,534,992
Ensembl chr13:71,906,702...72,367,980
JBrowse link
G Calcb calcitonin-related polypeptide, beta decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of CALCB mRNA CTD PMID:21808981 NCBI chr 1:184,271,116...184,276,480
Ensembl chr 1:184,271,590...184,276,475
JBrowse link
G Calcrl calcitonin receptor like receptor increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of CALCRL mRNA CTD PMID:21808981 NCBI chr 3:71,747,938...71,845,487
Ensembl chr 3:71,747,956...71,845,232
JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of CAMK2B mRNA CTD PMID:23537331 NCBI chr14:86,208,876...86,297,727
Ensembl chr14:86,208,901...86,297,652
JBrowse link
G Capg capping actin protein, gelsolin like multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CAPG mRNA] CTD PMID:18200517 NCBI chr 4:100,395,693...100,419,447
Ensembl chr 4:100,407,658...100,419,446
JBrowse link
G Capn1 calpain 1 multiple interactions
increases expression
EXP Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CAPN1 protein] CTD PMID:30503585 NCBI chr 1:221,346,081...221,370,965
Ensembl chr 1:221,346,066...221,370,322
JBrowse link
G Casp1 caspase 1 multiple interactions
increases expression
EXP bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of and results in increased cleavage of CASP1 protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP1 protein modified form]; Trinitrobenzenesulfonic Acid results in increased expression of and results in increased cleavage of CASP1 protein CTD PMID:30365937 PMID:30503585 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Casp12 caspase 12 multiple interactions
increases cleavage
EXP Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP12 protein modified form]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased cleavage of CASP12 protein] CTD PMID:30503585 NCBI chr 8:2,658,892...2,686,160
Ensembl chr 8:2,659,865...2,686,160
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
ISO
EXP
D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of CASP3 protein]; Trinitrobenzenesulfonic Acid results in increased cleavage of and results in increased activity of CASP3 protein
Trinitrobenzenesulfonic Acid results in increased expression of CASP3 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of CASP3 protein; Trinitrobenzenesulfonic Acid results in increased expression of CASP3 protein modified form
dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of and results in increased cleavage of CASP3 protein]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP3 protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of and results in increased cleavage of CASP3 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP3 protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP3 protein modified form]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of and results in increased activity of CASP3 protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP3 mRNA]; Trinitrobenzenesulfonic Acid results in increased activity of and results in increased cleavage of CASP3 protein; Trinitrobenzenesulfonic Acid results in increased expression of and results in increased activity of CASP3 protein
CTD PMID:22427801 PMID:24831514 PMID:26165751 PMID:30503585 PMID:33412153 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp4 caspase 4 multiple interactions EXP bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of and results in increased cleavage of CASP4 protein]; Trinitrobenzenesulfonic Acid results in increased expression of and results in increased cleavage of CASP4 protein CTD PMID:30365937 NCBI chr 8:2,616,391...2,651,682
Ensembl chr 8:2,635,851...2,651,652
JBrowse link
G Casp8 caspase 8 multiple interactions
decreases expression
EXP Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CASP8 protein modified form] CTD PMID:30503585 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 increases expression
multiple interactions
EXP Trinitrobenzenesulfonic Acid results in increased expression of CASP9 protein modified form
Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP9 protein modified form]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP9 protein modified form]
CTD PMID:30503585 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase increases expression
multiple interactions
decreases expression
ISO
EXP
Trinitrobenzenesulfonic Acid results in increased expression of CAT mRNA
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CAT mRNA]
CTD PMID:17982090 PMID:30503585 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression
increases secretion
multiple interactions
ISO
EXP
Trinitrobenzenesulfonic Acid results in increased expression of CCL2 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of CCL2 protein
Trinitrobenzenesulfonic Acid results in increased secretion of CCL2 protein
icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL2 protein]
Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL2 mRNA]; Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL2 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL2 mRNA]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL2 mRNA]
CTD PMID:17449585 PMID:17982090 PMID:23307618 PMID:23596210 PMID:30503585 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions
increases expression
ISO [cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein]; [rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein]; cholan-2,3,24-tryl-2,3,24-trisulfate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein]; icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein]; rifaximin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein] CTD PMID:21599020 PMID:23596210 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 multiple interactions
increases expression
ISO icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL4 protein] CTD PMID:23596210 NCBI chr10:70,870,926...70,886,357
Ensembl chr10:70,884,531...70,886,355
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CCL7 mRNA CTD PMID:17982090 NCBI chr10:69,423,083...69,424,933
Ensembl chr10:69,423,086...69,424,979
JBrowse link
G Ccn2 cellular communication network factor 2 multiple interactions
increases expression
ISO stattic inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCN2 mRNA] CTD PMID:25740948 NCBI chr 1:21,851,657...21,854,773
Ensembl chr 1:21,851,660...21,854,773
JBrowse link
G Ccn4 cellular communication network factor 4 multiple interactions
decreases expression
increases expression
ISO
EXP
NOS2 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCN4 mRNA]
Trinitrobenzenesulfonic Acid results in decreased expression of CCN4 mRNA
CTD PMID:19238344 PMID:23537331 NCBI chr 7:107,695,227...107,723,759
Ensembl chr 7:107,695,215...107,723,772
JBrowse link
G Ccnb1 cyclin B1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CCNB1 mRNA CTD PMID:17982090 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CCR2 mRNA CTD PMID:17982090
G Ccr5 C-C motif chemokine receptor 5 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CCR5 mRNA CTD PMID:15973123 PMID:17982090 NCBI chr 8:133,192,398...133,215,599
Ensembl chr 8:133,197,032...133,215,614
JBrowse link
G Cd14 CD14 molecule increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CD14 mRNA CTD PMID:17982090 NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153
JBrowse link
G Cd3g CD3g molecule decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of CD3G mRNA CTD PMID:23537331 NCBI chr 8:49,274,553...49,280,943
Ensembl chr 8:49,274,960...49,280,901
JBrowse link
G Cd44 CD44 molecule (Indian blood group) multiple interactions
increases expression
ISO seryl-leucyl-isoleucyl-glycyl--arginyl-leucinamide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CD44 protein] CTD PMID:11717450 NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658
JBrowse link
G Cd47 Cd47 molecule multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CD47 mRNA] CTD PMID:18200517 NCBI chr11:53,511,485...53,575,754
Ensembl chr11:53,514,595...53,575,175
JBrowse link
G Cd53 Cd53 molecule increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CD53 mRNA CTD PMID:17982090 NCBI chr 2:209,489,279...209,537,098
Ensembl chr 2:209,489,279...209,537,087
JBrowse link
G Cd79a CD79a molecule increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CD79A mRNA CTD PMID:17982090 NCBI chr 1:81,763,609...81,768,039
Ensembl chr 1:81,763,614...81,767,980
JBrowse link
G Cdh17 cadherin 17 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of CDH17 mRNA CTD PMID:12163651 NCBI chr 5:25,354,187...25,443,675
Ensembl chr 5:25,391,115...25,443,718
JBrowse link
G Cdr2 cerebellar degeneration-related protein 2 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CDR2 mRNA CTD PMID:17982090 NCBI chr 1:190,889,698...190,914,606
Ensembl chr 1:190,889,701...190,914,610
JBrowse link
G Ceacam4 CEA cell adhesion molecule 4 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CEACAM10 mRNA CTD PMID:17982090 NCBI chr 1:81,643,809...81,650,085
Ensembl chr 1:81,643,816...81,650,094
Ensembl chr 1:81,643,816...81,650,094
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CEBPB mRNA] CTD PMID:18200517 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Cel carboxyl ester lipase increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CEL mRNA CTD PMID:17982090 NCBI chr 3:7,134,021...7,141,522
Ensembl chr 3:7,134,021...7,141,522
JBrowse link
G Cela2a chymotrypsin like elastase 2A increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CELA2A mRNA CTD PMID:17982090 NCBI chr 5:160,374,031...160,383,782
Ensembl chr 5:160,374,031...160,383,782
JBrowse link
G Ces1d carboxylesterase 1D increases expression
decreases expression
multiple interactions
ISO Trinitrobenzenesulfonic Acid results in increased expression of CES1 mRNA
Trinitrobenzenesulfonic Acid results in decreased expression of CES1 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CES1 mRNA]
CTD PMID:18200517 PMID:19524605 PMID:22609641 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Ces3a carboxylesterase 3a decreases expression
multiple interactions
ISO Trinitrobenzenesulfonic Acid results in decreased expression of CES3 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CES3 mRNA]
CTD PMID:17982090 PMID:18200517 NCBI chr19:37,070,705...37,079,411 JBrowse link
G Cfd complement factor D decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of CFD mRNA CTD PMID:17982090 NCBI chr 7:12,634,216...12,635,939
Ensembl chr 7:12,634,216...12,635,943
JBrowse link
G Cfh complement factor H increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CFH mRNA CTD PMID:17982090 NCBI chr13:56,979,155...57,080,540
Ensembl chr13:56,978,607...57,080,622
JBrowse link
G Chi3l1 chitinase 3 like 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CHI3L1 mRNA CTD PMID:17982090 NCBI chr13:51,022,844...51,030,797
Ensembl chr13:51,022,681...51,030,802
JBrowse link
G Chkb choline kinase beta decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of CHKB mRNA CTD PMID:17982090 NCBI chr 7:130,404,818...130,408,813
Ensembl chr 7:130,404,832...130,408,187
JBrowse link
G Clca1 chloride channel accessory 1 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of CLCA1 mRNA CTD PMID:17982090 NCBI chr 2:250,897,980...250,923,711
Ensembl chr 2:250,897,969...250,923,744
JBrowse link
G Cldn1 claudin 1 multiple interactions
decreases expression
ISO ginsenoside Re inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CLDN1 protein] CTD PMID:22849695 NCBI chr11:77,815,216...77,830,373
Ensembl chr11:77,815,181...77,830,416
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions
increases expression
ISO stattic inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL1A1 mRNA] CTD PMID:17982090 PMID:25740948 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Col1a2 collagen type I alpha 2 chain multiple interactions
increases expression
ISO 6-diphenylmethyl-5-(5-isopropyl-2-methoxybenzylamino)-1-azabicyclo(2.2.2)octane-3-carboxylic acid inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL1A2 mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL1A2 mRNA]; TACR1 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL1A2 mRNA] CTD PMID:17982090 PMID:18200517 PMID:20889569 NCBI chr 4:31,534,225...31,569,152
Ensembl chr 4:31,534,225...31,569,151
JBrowse link
G Col4a1 collagen type IV alpha 1 chain multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL4A1 mRNA] CTD PMID:17982090 PMID:18200517 NCBI chr16:83,522,162...83,632,153
Ensembl chr16:83,522,162...83,632,153
JBrowse link
G Col4a2 collagen type IV alpha 2 chain multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL4A2 mRNA] CTD PMID:18200517 NCBI chr16:83,386,388...83,522,169
Ensembl chr16:83,387,364...83,438,561
JBrowse link
G Col5a1 collagen type V alpha 1 chain multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL5A1 mRNA] CTD PMID:18200517 NCBI chr 3:6,430,180...6,581,010
Ensembl chr 3:6,430,201...6,578,882
JBrowse link
G Col5a2 collagen type V alpha 2 chain multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL5A2 mRNA] CTD PMID:18200517 NCBI chr 9:52,091,088...52,238,735
Ensembl chr 9:52,092,511...52,238,564
JBrowse link
G Cort cortistatin increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of CORT protein CTD PMID:11959675 NCBI chr 5:165,942,780...165,944,221 JBrowse link
G Crh corticotropin releasing hormone decreases expression
increases expression
EXP Trinitrobenzenesulfonic Acid results in decreased expression of CRH mRNA
Trinitrobenzenesulfonic Acid results in increased expression of CRH mRNA
CTD PMID:11668029 PMID:11959675 NCBI chr 2:104,459,999...104,461,863
Ensembl chr 2:104,459,999...104,461,863
JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of CRHR1 mRNA CTD PMID:15178552 NCBI chr10:92,191,473...92,233,662
Ensembl chr10:92,191,718...92,232,645
JBrowse link
G Csf2rb colony stimulating factor 2 receptor subunit beta multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CSF2RB mRNA] CTD PMID:18200517 NCBI chr 7:119,554,383...119,568,248
Ensembl chr 7:119,554,354...119,568,776
JBrowse link
G Csf3 colony stimulating factor 3 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CSF3 protein CTD PMID:23596210 NCBI chr10:86,616,785...86,619,160
Ensembl chr10:86,616,785...86,619,157
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions
increases expression
EXP geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CTNNB1 mRNA]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CTNNB1 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CTNNB1 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CTNNB1 protein]
Trinitrobenzenesulfonic Acid results in increased expression of CTNNB1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of CTNNB1 protein
CTD PMID:26165751 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Ctsc cathepsin C increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CTSC mRNA CTD PMID:17982090 NCBI chr 1:151,918,514...151,949,979
Ensembl chr 1:151,918,571...151,949,983
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CX3CL1 mRNA CTD PMID:15973123 NCBI chr19:10,644,267...10,654,861
Ensembl chr19:10,644,244...10,653,800
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CXCL10 protein CTD PMID:23596210 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CXCL12 mRNA CTD PMID:15973123 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Cxcl13 C-X-C motif chemokine ligand 13 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CXCL13 mRNA CTD PMID:15973123 NCBI chr14:15,253,146...15,258,221
Ensembl chr14:15,253,125...15,258,207
JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CXCL14 mRNA CTD PMID:15973123 NCBI chr17:9,109,731...9,117,754
Ensembl chr17:9,109,731...9,117,750
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CXCL2 mRNA] CTD PMID:17375199 PMID:18200517 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions
increases expression
ISO icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CXCL1 protein]
Trinitrobenzenesulfonic Acid results in increased expression of CXCL1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of CXCL1 protein
CTD PMID:17982090 PMID:23596210 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CXCL9 mRNA CTD PMID:17982090 NCBI chr14:17,228,832...17,233,743
Ensembl chr14:17,228,856...17,234,712
JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of CXCR2 mRNA CTD PMID:15973123 NCBI chr 9:81,427,275...81,435,065
Ensembl chr 9:81,427,730...81,434,102
JBrowse link
G Cycs cytochrome c, somatic multiple interactions
increases expression
EXP Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CYCS protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CYCS mRNA]
Trinitrobenzenesulfonic Acid results in increased expression of CYCS mRNA; Trinitrobenzenesulfonic Acid results in increased expression of CYCS protein
CTD PMID:24831514 PMID:30503585 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions EXP Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP1A2 protein CTD PMID:18079364 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 multiple interactions EXP gadolinium chloride inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP2C11 protein]; Polymyxin B inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP2C11 protein]; Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP2C11 protein CTD PMID:18079364 NCBI chr 1:257,676,172...258,004,428
Ensembl chr 1:257,970,345...258,004,434
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions EXP Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP2E1 protein CTD PMID:18079364 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions EXP gadolinium chloride inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP3A2 protein]; nimesulide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP3A2 protein]; Polymyxin B inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP3A2 protein]; Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP3A2 protein CTD PMID:18079364 NCBI chr12:11,641,500...11,677,818
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of CYP3A13 mRNA CTD PMID:17982090 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
JBrowse link
G Dcp2 decapping mRNA 2 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of DCP2 mRNA CTD PMID:12163651 NCBI chr18:35,489,274...35,671,676
Ensembl chr18:35,489,274...35,672,291
JBrowse link
G Defb2 defensin beta 2 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of DEFB2 mRNA CTD PMID:19998380 NCBI chr16:75,227,468...75,241,303
Ensembl chr16:75,227,468...75,241,303
JBrowse link
G Dnaaf5 dynein, axonemal, assembly factor 5 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of DNAAF5 mRNA CTD PMID:17982090 NCBI chr12:17,545,468...17,584,466
Ensembl chr12:17,545,468...17,584,466
JBrowse link
G Dpp4 dipeptidylpeptidase 4 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of DPP4 mRNA CTD PMID:12163651 NCBI chr 3:48,291,055...48,372,672
Ensembl chr 3:48,291,055...48,372,672
JBrowse link
G Dsg2 desmoglein 2 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of DSG2 mRNA CTD PMID:17982090 NCBI chr18:15,579,322...15,637,720
Ensembl chr18:15,579,315...15,637,715
JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of EEF1A1 mRNA CTD PMID:12163651 NCBI chr 8:85,838,594...85,841,816
Ensembl chr 8:85,838,869...85,840,818
JBrowse link
G Eif4a2 eukaryotic translation initiation factor 4A2 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of EIF4A2 mRNA CTD PMID:12163651 NCBI chr11:81,373,047...81,379,680
Ensembl chr11:81,373,048...81,379,871
JBrowse link
G Eif4ebp2 eukaryotic translation initiation factor 4E binding protein 2 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of EIF4EBP2 mRNA CTD PMID:17982090 NCBI chr20:31,055,292...31,072,469
Ensembl chr20:31,055,789...31,072,469
JBrowse link
G Emb embigin multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of EMB mRNA] CTD PMID:18200517 NCBI chr 2:49,682,763...49,733,475
Ensembl chr 2:49,682,754...49,732,253
JBrowse link
G Ephb3 Eph receptor B3 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of EPHB3 mRNA CTD PMID:17982090 NCBI chr11:83,527,960...83,546,742
Ensembl chr11:83,527,962...83,546,674
JBrowse link
G Fabp2 fatty acid binding protein 2 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of FABP2 mRNA CTD PMID:17982090 NCBI chr 2:227,080,912...227,083,654
Ensembl chr 2:227,080,924...227,083,501
JBrowse link
G Faslg Fas ligand multiple interactions
increases expression
ISO D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of FASL protein]
Trinitrobenzenesulfonic Acid results in increased expression of FASL protein
CTD PMID:22427801 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fbln2 fibulin 2 multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of FBLN2 mRNA] CTD PMID:18200517 NCBI chr 4:122,835,237...122,895,127
Ensembl chr 4:122,835,436...122,895,121
JBrowse link
G Fbxl2 F-box and leucine-rich repeat protein 2 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of FBXL2 mRNA CTD PMID:12163651 NCBI chr 8:122,240,393...122,290,439
Ensembl chr 8:122,243,016...122,311,431
JBrowse link
G Fcgr2b Fc fragment of IgG receptor IIb increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of FCGR2B mRNA CTD PMID:19524605 NCBI chr13:89,329,298...89,343,916
Ensembl chr13:89,327,794...89,433,815
JBrowse link
G Fcgr3a Fc fragment of IgG receptor IIIa multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of FCGR3A mRNA] CTD PMID:18200517 NCBI chr13:89,385,775...89,396,047
Ensembl chr13:89,385,859...89,396,051
JBrowse link
G Fgf17 fibroblast growth factor 17 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of FGF17 mRNA CTD PMID:23537331 NCBI chr15:52,326,758...52,337,360
Ensembl chr15:52,326,778...52,332,097
JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of FGFR3 mRNA CTD PMID:23537331 NCBI chr14:82,272,322...82,287,739
Ensembl chr14:82,273,070...82,287,706
JBrowse link
G Fn1 fibronectin 1 multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of FN1 mRNA] CTD PMID:18200517 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of FOS mRNA CTD PMID:15178552 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Fpr3 formyl peptide receptor 3 multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of FPR3 mRNA] CTD PMID:18200517 NCBI chr 1:116,152,526...116,161,873
Ensembl chr 1:116,152,667...116,153,722
JBrowse link
G Fstl1 follistatin-like 1 multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of FSTL1 mRNA] CTD PMID:18200517 NCBI chr11:65,791,196...65,845,721
Ensembl chr11:65,782,567...65,845,418
JBrowse link
G Fxyd5 FXYD domain-containing ion transport regulator 5 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of FXYD5 mRNA CTD PMID:23537331 NCBI chr 1:89,464,853...89,474,450
Ensembl chr 1:89,464,860...89,474,252
JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of GABBR1 mRNA CTD PMID:17982090 NCBI chr20:1,955,344...1,984,907
Ensembl chr20:1,955,359...1,984,863
JBrowse link
G Gbp2 guanylate binding protein 2 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of GBP2 mRNA CTD PMID:17982090 NCBI chr 2:248,276,795...248,293,784
Ensembl chr 2:248,276,709...248,293,784
JBrowse link
G Gbp4 guanylate binding protein 4 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of GBP3 mRNA CTD PMID:17982090 NCBI chr 2:248,249,232...248,263,104
Ensembl chr 2:248,249,468...248,263,168
JBrowse link
G Gch1 GTP cyclohydrolase 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of GCH1 mRNA CTD PMID:17982090 NCBI chr15:23,935,011...23,968,971
Ensembl chr15:23,934,585...23,969,011
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions EXP [Trinitrobenzenesulfonic Acid co-treated with Ethanol] results in increased expression of GCLC mRNA CTD PMID:10830784 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of GCLM mRNA CTD PMID:22609641 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Gda guanine deaminase multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GDA mRNA] CTD PMID:18200517 NCBI chr 1:238,982,542...239,057,663
Ensembl chr 1:238,982,392...239,057,732
JBrowse link
G Gdpd3 glycerophosphodiester phosphodiesterase domain containing 3 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of GDPD3 mRNA CTD PMID:17982090 NCBI chr 1:198,199,032...198,209,178
Ensembl chr 1:198,199,622...198,209,150
JBrowse link
G Ggta1 glycoprotein alpha-galactosyltransferase 1 increases expression
multiple interactions
ISO Trinitrobenzenesulfonic Acid results in increased expression of GGTA1 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GGTA1 mRNA]
CTD PMID:18200517 NCBI chr 3:14,614,099...14,701,185
Ensembl chr 3:14,614,122...14,644,951
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 multiple interactions
decreases expression
EXP Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of GOT1 mRNA] CTD PMID:30503585 NCBI chr 1:263,246,248...263,269,762
Ensembl chr 1:263,246,248...263,269,762
JBrowse link
G Got1l1 glutamic-oxaloacetic transaminase 1-like 1 multiple interactions
decreases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of GOT1L1 mRNA] CTD PMID:18200517 NCBI chr16:69,022,756...69,035,507
Ensembl chr16:69,022,784...69,028,179
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 decreases expression
multiple interactions
EXP Trinitrobenzenesulfonic Acid results in decreased expression of GOT2 mRNA
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of GOT2 mRNA]
CTD PMID:30503585 NCBI chr19:9,587,637...9,613,323
Ensembl chr19:9,587,653...9,613,340
JBrowse link
G Gpx2 glutathione peroxidase 2 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of GPX2 mRNA CTD PMID:31669340 NCBI chr 6:99,839,960...99,843,245
Ensembl chr 6:99,839,960...99,843,245
JBrowse link
G Grb10 growth factor receptor bound protein 10 multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GRB10 mRNA] CTD PMID:18200517 NCBI chr14:92,021,851...92,122,249
Ensembl chr14:92,021,851...92,117,923
JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist increases expression
multiple interactions
ISO Trinitrobenzenesulfonic Acid results in increased expression of GREM1 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GREM1 mRNA]
CTD PMID:18200517 NCBI chr 3:105,203,309...105,214,989
Ensembl chr 3:105,203,309...105,214,989
JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of GRIA2 mRNA CTD PMID:23537331 NCBI chr 2:179,584,302...179,704,629
Ensembl chr 2:179,584,308...179,704,629
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta increases expression
multiple interactions
EXP Trinitrobenzenesulfonic Acid results in increased expression of GSK3B protein
geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GSK3B protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GSK3B protein]
CTD PMID:26165751 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Gsn gelsolin multiple interactions
decreases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of GSN mRNA] CTD PMID:17982090 PMID:18200517 NCBI chr 3:14,456,106...14,508,922
Ensembl chr 3:14,467,330...14,508,911
JBrowse link
G Gsr glutathione-disulfide reductase decreases activity
decreases expression
multiple interactions
EXP Trinitrobenzenesulfonic Acid results in decreased activity of GSR protein
Trinitrobenzenesulfonic Acid results in decreased expression of GSR mRNA
4-methylesculetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased activity of GSR protein]; 4-methylesculetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of GSR mRNA]
CTD PMID:31669340 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gstm2 glutathione S-transferase mu 2 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of GSTM2 mRNA CTD PMID:17982090 NCBI chr 2:210,778,041...210,782,807
Ensembl chr 2:210,720,704...210,782,856
JBrowse link
G Gstt1 glutathione S-transferase theta 1 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of GSTT1 mRNA CTD PMID:31669340 NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 increases expression
increases secretion
EXP Trinitrobenzenesulfonic Acid results in increased expression of HAVCR1 mRNA
Trinitrobenzenesulfonic Acid results in increased secretion of HAVCR1 protein
CTD PMID:23307618 NCBI chr10:31,813,819...31,860,934
Ensembl chr10:31,813,814...31,848,379
JBrowse link
G Hebp2 heme binding protein 2 increases expression
multiple interactions
ISO Trinitrobenzenesulfonic Acid results in increased expression of HEBP2 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of HEBP2 mRNA]
CTD PMID:18200517 NCBI chr 1:13,713,152...13,719,970
Ensembl chr 1:13,714,440...13,719,829
JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions
increases expression
EXP dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of HMGB1 protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of HMGB1 protein] CTD PMID:33412153 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of HMGCR mRNA CTD PMID:17982090 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
decreases expression
increases expression
EXP dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of HMOX1 protein]; Heme promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of and results in increased activity of HMOX1 protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of HMOX1 protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of HMOX1 protein]; Trinitrobenzenesulfonic Acid results in increased expression of and results in increased activity of HMOX1 protein; zinc protoporphyrin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of HMOX1 protein]
Trinitrobenzenesulfonic Acid results in increased expression of HMOX1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of HMOX1 protein
CTD PMID:17292349 PMID:25469038 PMID:30503585 PMID:33412153 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hoxd13 homeo box D13 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of HOXD13 mRNA CTD PMID:17982090 NCBI chr 3:61,590,376...61,593,692
Ensembl chr 3:61,590,376...61,593,692
JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase affects expression EXP Trinitrobenzenesulfonic Acid affects the expression of HPGD mRNA CTD PMID:25526689 NCBI chr16:37,457,134...37,495,758
Ensembl chr16:37,457,135...37,495,758
JBrowse link
G Hrh4 histamine receptor H4 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of HRH4 mRNA CTD PMID:24561612 NCBI chr18:4,365,429...4,382,599
Ensembl chr18:4,365,429...4,382,599
JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of HSD11B1 mRNA CTD PMID:21513799 NCBI chr13:111,946,626...111,996,536
Ensembl chr13:111,926,442...111,972,603
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression
multiple interactions
EXP Trinitrobenzenesulfonic Acid results in increased expression of HSPA5 protein
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of HSPA5 protein]
CTD PMID:30503585 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hspb7 heat shock protein family B (small) member 7 multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of HSPB7 mRNA] CTD PMID:18200517 NCBI chr 5:159,968,077...159,971,563
Ensembl chr 5:159,967,839...159,971,562
JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of HTR1A mRNA CTD PMID:23537331 NCBI chr 2:36,246,628...36,247,896
Ensembl chr 2:36,246,628...36,247,896
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of HTR2A mRNA CTD PMID:23537331 NCBI chr15:56,666,152...56,732,469
Ensembl chr15:56,666,012...56,735,382
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions
increases expression
ISO
EXP
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 mRNA]
Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 protein
cinnamic aldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 protein]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 protein]; hesperetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 protein]; Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 mRNA]; Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 protein]; Resveratrol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 mRNA]
CTD PMID:18200517 PMID:22029500 PMID:26165751 PMID:30503585 PMID:31428839 PMID:33522063 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of IDO1 mRNA CTD PMID:17982090 NCBI chr16:72,216,326...72,228,098
Ensembl chr16:72,216,326...72,228,098
JBrowse link
G Ifi27 interferon, alpha-inducible protein 27 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of IFI27 mRNA CTD PMID:17982090 NCBI chr 6:127,327,959...127,334,430
Ensembl chr 6:127,327,959...127,334,428
JBrowse link
G Ifi30 IFI30, lysosomal thiol reductase multiple interactions EXP [topiramate co-treated with Trinitrobenzenesulfonic Acid] results in decreased expression of IFI30 mRNA CTD PMID:21849664 NCBI chr16:20,426,566...20,430,772
Ensembl chr16:20,426,566...20,430,752
JBrowse link
G Ifit2 interferon-induced protein with tetratricopeptide repeats 2 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of IFIT2 mRNA CTD PMID:17982090 NCBI chr 1:252,894,663...252,900,727
Ensembl chr 1:252,894,663...252,900,726
JBrowse link
G Ifitm3 interferon induced transmembrane protein 3 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of IFITM3 mRNA CTD PMID:17982090 NCBI chr 1:213,810,712...213,811,821
Ensembl chr 1:213,810,696...213,811,901
JBrowse link
G Ifnb1 interferon beta 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of IFNB1 mRNA CTD PMID:17375199 NCBI chr 5:106,865,192...106,865,746
Ensembl chr 5:106,865,192...106,865,746
JBrowse link
G Ifng interferon gamma multiple interactions
increases expression
decreases expression
EXP
ISO
bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG mRNA]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]
Trinitrobenzenesulfonic Acid results in decreased expression of IFNG mRNA
Trinitrobenzenesulfonic Acid results in increased expression of IFNG; Trinitrobenzenesulfonic Acid results in increased expression of IFNG mRNA; Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein
[cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]; [rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]; cholan-2,3,24-tryl-2,3,24-trisulfate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]; dai-kenchu-to inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG]; Minocycline inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG mRNA]; rifaximin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]; seryl-leucyl-isoleucyl-glycyl--arginyl-leucinamide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG mRNA]; sinomenine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG mRNA]; sinomenine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]
CTD PMID:11717450 PMID:15973123 PMID:16782535 PMID:16867261 PMID:19285099 PMID:20136961 PMID:21122500 PMID:21599020 PMID:21829567 PMID:22147983 PMID:23027085 PMID:23537331 PMID:23747339 PMID:24066068 PMID:27783946 PMID:30365937 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions
increases expression
ISO
EXP
6-diphenylmethyl-5-(5-isopropyl-2-methoxybenzylamino)-1-azabicyclo(2.2.2)octane-3-carboxylic acid inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IGF1 protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IGF1 mRNA]; TACR1 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IGF1 protein]
Trinitrobenzenesulfonic Acid results in increased expression of IGF1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of IGF1 protein
CTD PMID:18200517 PMID:20889569 PMID:24782617 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IGFBP4 mRNA] CTD PMID:18200517 NCBI chr10:86,950,555...86,962,563
Ensembl chr10:86,950,557...86,962,578
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IGFBP5 mRNA] CTD PMID:17982090 PMID:18200517 NCBI chr 9:80,154,230...80,166,813
Ensembl chr 9:80,150,211...80,167,033
JBrowse link
G Il10 interleukin 10 multiple interactions
decreases secretion
increases expression
decreases expression
EXP
ISO
[iberogast analog co-treated with Trinitrobenzenesulfonic Acid] results in increased expression of IL10 mRNA; [iberogast co-treated with Trinitrobenzenesulfonic Acid] results in increased expression of IL10 mRNA; bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL10 protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL10 mRNA]; dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL10 protein]; Isatin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL10]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL10 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL10 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL10 protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL10 protein]
Trinitrobenzenesulfonic Acid results in decreased secretion of IL10 protein
Trinitrobenzenesulfonic Acid results in increased expression of IL10 mRNA
Trinitrobenzenesulfonic Acid results in decreased expression of IL10; Trinitrobenzenesulfonic Acid results in decreased expression of IL10 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of IL10 protein
[cholan-2,3,24-tryl-2,3,24-trisulfate co-treated with Trinitrobenzenesulfonic Acid] results in increased expression of IL10 protein; [rifaximin co-treated with Trinitrobenzenesulfonic Acid] results in increased expression of IL10 protein; seryl-leucyl-isoleucyl-glycyl--arginyl-leucinamide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL10 mRNA]; soyasaponin Ab inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL10 protein]
CTD PMID:11717450 PMID:15604057 PMID:15973123 PMID:16867261 PMID:17375199 PMID:19196500 PMID:21599020 PMID:21829567 PMID:22060784 PMID:24316276 PMID:24831514 PMID:25307695 PMID:25727887 PMID:25729217 PMID:30365937 PMID:33412153 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il12a interleukin 12A increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of IL12A mRNA CTD PMID:15973123 NCBI chr 2:165,076,945...165,083,996
Ensembl chr 2:165,076,607...165,084,318
JBrowse link
G Il12b interleukin 12B decreases response to substance
increases expression
multiple interactions
ISO
EXP
IL12B protein results in decreased susceptibility to Trinitrobenzenesulfonic Acid
Trinitrobenzenesulfonic Acid results in increased expression of IL12B mRNA; Trinitrobenzenesulfonic Acid results in increased expression of IL12B protein
icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL12B protein]
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL12B mRNA]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL12B mRNA]
CTD PMID:11782017 PMID:16867261 PMID:17375199 PMID:23596210 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
JBrowse link
G Il15 interleukin 15 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of IL15 protein CTD PMID:23596210 NCBI chr19:23,542,606...23,624,366
Ensembl chr19:23,542,889...23,554,594
JBrowse link
G Il17a interleukin 17A increases expression
multiple interactions
ISO
EXP
Trinitrobenzenesulfonic Acid results in increased expression of IL17A mRNA; Trinitrobenzenesulfonic Acid results in increased expression of IL17A protein
Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL17A protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL17A protein]
[Trinitrobenzenesulfonic Acid results in increased susceptibility to [Ionomycin co-treated with Tetradecanoylphorbol Acetate]] which results in increased expression of IL17A protein
CTD PMID:17375199 PMID:23027085 PMID:27783946 PMID:31428839 NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786
JBrowse link
G Il18 interleukin 18 increases expression
multiple interactions
ISO
EXP
Trinitrobenzenesulfonic Acid results in increased expression of IL18 mRNA
bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL18 protein]
CTD PMID:15973123 PMID:30365937 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il1a interleukin 1 alpha increases expression
multiple interactions
ISO Trinitrobenzenesulfonic Acid results in increased expression of IL1A mRNA
icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1A protein]
CTD PMID:12781210 PMID:23596210 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
ISO
EXP
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Huangqin-Tang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; lancemaside A inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; soyasaponin Ab inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; soyasaponin I inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]
Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA; Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein
4-methylesculetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; [allicin co-treated with Mesalamine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; [allicin co-treated with Mesalamine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; [allicin co-treated with Sulfasalazine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; [allicin co-treated with Sulfasalazine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; [Inosine Monophosphate co-treated with potassium oxonate] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Alendronate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; allicin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; allicin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]]; Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Dinoprostone analog inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Inosine Monophosphate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; kappa-casein glycomacropeptide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; nitroaspirin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; potassium oxonate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Prednisolone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; SC 560 promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; SCH 442416 inhibits the reaction [Inosine Monophosphate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]
CTD PMID:15140218 PMID:15604057 PMID:15793857 PMID:15867298 PMID:15973123 PMID:16782535 PMID:16867261 PMID:17375077 PMID:17375199 PMID:17449585 PMID:17982090 PMID:18200517 PMID:19597321 PMID:19956958 PMID:20868668 PMID:20923188 PMID:21513799 PMID:21829567 PMID:21893697 PMID:22039321 PMID:22060784 PMID:22119283 PMID:22609641 PMID:23596210 PMID:23747339 PMID:25079872 PMID:25307695 PMID:25576893 PMID:25727887 PMID:25729217 PMID:26165751 PMID:30365937 PMID:30503585 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1r1 interleukin 1 receptor type 1 multiple interactions
increases expression
EXP Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1R1 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1R1 mRNA] CTD PMID:17449585 NCBI chr 9:46,962,291...47,038,139
Ensembl chr 9:46,962,288...47,036,670
JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of IL1RL1 mRNA CTD PMID:17982090 NCBI chr 9:47,133,483...47,184,316
Ensembl chr 9:47,134,034...47,182,170
JBrowse link
G Il1rn interleukin 1 receptor antagonist multiple interactions
increases expression
EXP Alendronate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1RN mRNA]; kappa-casein glycomacropeptide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1RN mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1RN mRNA] CTD PMID:15867298 PMID:17375077 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
JBrowse link
G Il2 interleukin 2 multiple interactions
increases expression
ISO seryl-leucyl-isoleucyl-glycyl--arginyl-leucinamide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL2 mRNA] CTD PMID:11717450 PMID:27783946 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il23a interleukin 23 subunit alpha increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of IL23A mRNA CTD PMID:17375199 NCBI chr 7:2,710,609...2,712,723
Ensembl chr 7:2,710,609...2,712,723
JBrowse link
G Il4 interleukin 4 increases expression
decreases secretion
decreases expression
multiple interactions
ISO
EXP
Trinitrobenzenesulfonic Acid results in increased expression of IL4 mRNA
Trinitrobenzenesulfonic Acid results in decreased secretion of IL4 protein
Trinitrobenzenesulfonic Acid results in decreased expression of IL4 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of IL4 protein
[allicin co-treated with Mesalamine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased secretion of IL4 protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL4 mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL4 protein]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL4 mRNA]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL4 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased secretion of IL4 protein]
CTD PMID:15973123 PMID:16782535 PMID:16867261 PMID:25729217 PMID:27783946 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il6 interleukin 6 multiple interactions
decreases expression
increases expression
ISO
EXP
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; Huangqin-Tang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; lancemaside A inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; notoginsenoside R1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; soyasaponin Ab inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; soyasaponin I inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]
Trinitrobenzenesulfonic Acid results in decreased expression of IL6 mRNA
Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein
Chalcones inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; Chalcones inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; cinnamic aldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; hesperetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; Iridoid Glycosides inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]
Trinitrobenzenesulfonic Acid results in increased expression of IL6; Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of IL6 protein
CTD PMID:17375199 PMID:18079364 PMID:18200517 PMID:19956958 PMID:19998380 PMID:20923188 PMID:21070844 PMID:21829567 PMID:22060784 PMID:22410118 PMID:23027085 PMID:23596210 PMID:23747339 PMID:25307695 PMID:25472953 PMID:25576893 PMID:30503585 PMID:31428839 PMID:33522063 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Insl3 insulin-like 3 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of INSL3 mRNA CTD PMID:23537331 NCBI chr16:20,120,753...20,122,702
Ensembl chr16:20,121,352...20,122,696
JBrowse link
G Irf1 interferon regulatory factor 1 decreases response to substance ISO IRF1 protein results in decreased susceptibility to Trinitrobenzenesulfonic Acid CTD PMID:21097874 NCBI chr10:39,109,530...39,116,532
Ensembl chr10:39,109,522...39,116,531
JBrowse link
G Isg15 ISG15 ubiquitin-like modifier increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of ISG15 mRNA CTD PMID:17982090 NCBI chr 5:173,624,862...173,629,124
Ensembl chr 5:173,624,310...173,626,248
JBrowse link
G Itm2a integral membrane protein 2A multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ITM2A mRNA] CTD PMID:18200517 NCBI chr  X:78,490,872...78,496,814
Ensembl chr  X:78,490,866...78,496,847
JBrowse link
G Itpr2 inositol 1,4,5-trisphosphate receptor, type 2 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of ITPR2 mRNA CTD PMID:23537331 NCBI chr 4:180,423,452...180,800,088
Ensembl chr 4:180,538,389...180,722,358
JBrowse link
G Jak2 Janus kinase 2 increases phosphorylation
multiple interactions
EXP Trinitrobenzenesulfonic Acid results in increased phosphorylation of JAK2 protein
cinnamic aldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of JAK2 protein]; hesperetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of JAK2 protein]
CTD PMID:33522063 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of and results in increased phosphorylation of JUN protein]; Trinitrobenzenesulfonic Acid results in increased expression of and results in increased phosphorylation of JUN protein CTD PMID:22427801 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Kcnab1 potassium voltage-gated channel subfamily A regulatory beta subunit 1 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of KCNAB1 mRNA CTD PMID:23537331 NCBI chr 2:155,555,798...156,011,438
Ensembl chr 2:155,718,359...156,009,526
JBrowse link
G Kcnj4 potassium inwardly-rectifying channel, subfamily J, member 4 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of KCNJ4 mRNA CTD PMID:23537331 NCBI chr 7:120,717,378...120,744,602
Ensembl chr 7:120,717,375...120,744,602
JBrowse link
G Kcnq4 potassium voltage-gated channel subfamily Q member 4 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of KCNQ4 mRNA CTD PMID:23537331 NCBI chr 5:139,625,783...139,677,300
Ensembl chr 5:139,627,576...139,677,300
JBrowse link
G Kctd9 potassium channel tetramerization domain containing 9 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of KCTD9 mRNA CTD PMID:23537331 NCBI chr15:44,411,591...44,439,645
Ensembl chr15:44,411,865...44,439,236
JBrowse link
G Kitlg KIT ligand increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of KITLG mRNA CTD PMID:17385238 NCBI chr 7:42,269,784...42,351,054
Ensembl chr 7:42,269,784...42,351,054
JBrowse link
G Kl Klotho multiple interactions
decreases expression
ISO KL protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TRPV5 protein]
Trinitrobenzenesulfonic Acid results in decreased expression of KL protein
CTD PMID:23747339 NCBI chr12:942,974...987,206
Ensembl chr12:943,006...987,551
JBrowse link
G L1cam L1 cell adhesion molecule increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of L1CAM mRNA CTD PMID:17982090 NCBI chr  X:156,901,244...156,928,064
Ensembl chr  X:156,909,913...156,928,057
JBrowse link
G Lama3 laminin subunit alpha 3 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of LAMA3 mRNA CTD PMID:17982090 NCBI chr18:3,704,866...3,941,215
Ensembl chr18:3,705,916...3,940,838
JBrowse link
G Lbp lipopolysaccharide binding protein multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LBP mRNA] CTD PMID:18200517 NCBI chr 3:154,786,232...154,812,910
Ensembl chr 3:154,786,215...154,813,464
JBrowse link
G Lcn2 lipocalin 2 multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LCN2 mRNA] CTD PMID:17982090 PMID:18200517 NCBI chr 3:11,414,189...11,417,534
Ensembl chr 3:11,414,186...11,417,546
JBrowse link
G Lcp1 lymphocyte cytosolic protein 1 increases expression
multiple interactions
ISO Trinitrobenzenesulfonic Acid results in increased expression of LCP1 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LCP1 mRNA]
CTD PMID:18200517 NCBI chr15:57,170,566...57,277,811
Ensembl chr15:57,221,292...57,277,811
JBrowse link
G Lgmn legumain multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LGMN mRNA] CTD PMID:18200517 NCBI chr 6:126,282,246...126,308,207
Ensembl chr 6:126,282,233...126,320,726
JBrowse link
G Lilrb4 leukocyte immunoglobulin like receptor B4 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of LILRB4 mRNA CTD PMID:17982090 NCBI chr 1:73,393,854...73,399,448
Ensembl chr 1:73,393,850...73,399,579
JBrowse link
G LOC100365958 Rdh2 protein-like increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of RDH16 mRNA CTD PMID:17982090 NCBI chr 7:71,065,077...71,074,128
Ensembl chr 7:70,980,422...71,072,689
JBrowse link
G Lox lysyl oxidase multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LOX mRNA] CTD PMID:17982090 PMID:18200517 NCBI chr18:47,500,320...47,577,819
Ensembl chr18:47,500,330...47,577,819
JBrowse link
G Lrg1 leucine-rich alpha-2-glycoprotein 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of LRG1 mRNA CTD PMID:17982090 NCBI chr 9:10,952,424...10,954,664
Ensembl chr 9:10,952,374...10,954,681
JBrowse link
G Lst1 leukocyte specific transcript 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of LST1 mRNA CTD PMID:17982090 NCBI chr20:5,175,213...5,179,352
Ensembl chr20:5,176,016...5,179,263
JBrowse link
G Lum lumican increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of LUM mRNA CTD PMID:17982090 NCBI chr 7:38,820,058...38,826,862
Ensembl chr 7:38,819,771...38,826,862
JBrowse link
G Ly86 lymphocyte antigen 86 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of LY86 mRNA CTD PMID:17982090 NCBI chr17:28,104,535...28,191,447
Ensembl chr17:28,104,589...28,191,436
JBrowse link
G Lyz2 lysozyme 2 multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LYZ mRNA] CTD PMID:17982090 PMID:18200517 NCBI chr 7:60,335,968...60,341,264
Ensembl chr 7:60,335,969...60,341,264
JBrowse link
G Madcam1 mucosal vascular addressin cell adhesion molecule 1 multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MADCAM1 mRNA] CTD PMID:18200517 NCBI chr 7:12,918,352...12,922,509
Ensembl chr 7:12,918,710...12,922,112
JBrowse link
G Maf MAF bZIP transcription factor increases expression
multiple interactions
ISO Trinitrobenzenesulfonic Acid results in increased expression of MAF mRNA; Trinitrobenzenesulfonic Acid results in increased expression of MAF protein
sinomenine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MAF mRNA]; sinomenine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MAF protein]
CTD PMID:24066068 NCBI chr19:48,179,826...48,200,995
Ensembl chr19:48,194,804...48,196,748
JBrowse link
G Manf mesencephalic astrocyte-derived neurotrophic factor increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of MANF mRNA CTD PMID:17982090 NCBI chr 8:115,623,175...115,626,408
Ensembl chr 8:115,623,178...115,626,380
JBrowse link
G Maoa monoamine oxidase A multiple interactions
decreases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of MAOA mRNA] CTD PMID:18200517 NCBI chr  X:6,554,698...6,620,722
Ensembl chr  X:6,554,698...6,620,722
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions
increases lipidation
EXP Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased lipidation of MAP1LC3B protein] CTD PMID:30503585 NCBI chr19:53,635,449...53,643,970
Ensembl chr19:53,629,779...53,646,058
JBrowse link
G Map3k6 mitogen-activated protein kinase kinase kinase 6 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of MAP3K6 mRNA CTD PMID:23537331 NCBI chr 5:151,435,679...151,448,329
Ensembl chr 5:151,436,464...151,448,328
JBrowse link
G Mapk6 mitogen-activated protein kinase 6 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of MAPK6 mRNA CTD PMID:23537331 NCBI chr 8:82,328,013...82,351,108
Ensembl chr 8:82,328,020...82,351,108
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of MAPK8 mRNA CTD PMID:23537331 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions
increases expression
ISO [Trinitrobenzenesulfonic Acid results in increased expression of MAPK9 protein] promotes the reaction [BCL2L11 protein binds to MAPK9 protein]; D-JNKI-1 inhibits the reaction [[Trinitrobenzenesulfonic Acid results in increased expression of MAPK9 protein] promotes the reaction [BCL2L11 protein binds to MAPK9 protein]]; D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MAPK9 protein] CTD PMID:22427801 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Marcksl1 MARCKS-like 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of MARCKSL1 mRNA CTD PMID:17982090 NCBI chr 5:147,714,163...147,716,486
Ensembl chr 5:147,714,163...147,716,485
JBrowse link
G Me1 malic enzyme 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of ME1 mRNA CTD PMID:17982090 NCBI chr 8:94,256,830...94,368,834
Ensembl chr 8:94,256,839...94,368,834
JBrowse link
G Mettl7a methyltransferase like 7A multiple interactions
decreases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of METTL7A mRNA] CTD PMID:18200517 NCBI chr 7:141,973,447...142,021,344
Ensembl chr 7:141,973,553...141,981,432
JBrowse link
G Mgp matrix Gla protein increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of MGP mRNA CTD PMID:17982090 NCBI chr 4:170,856,783...170,860,105
Ensembl chr 4:170,856,751...170,860,225
JBrowse link
G Mir155 microRNA 155 increases expression
multiple interactions
ISO Trinitrobenzenesulfonic Acid results in increased expression of MIR155 mRNA
sinomenine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MIR155 mRNA]
CTD PMID:24066068 NCBI chr11:24,176,603...24,176,667
Ensembl chr11:24,176,603...24,176,667
JBrowse link
G Mir29a microRNA 29a increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of MIR29A mRNA CTD PMID:25277410 NCBI chr 4:58,343,931...58,344,018 JBrowse link
G Mir29b1 microRNA 29b-1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of MIR29B-1 mRNA CTD PMID:25277410 NCBI chr 4:58,344,310...58,344,390
Ensembl chr 4:58,344,310...58,344,390
JBrowse link
G Mki67 marker of proliferation Ki-67 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of MKI67 mRNA CTD PMID:17982090 NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454
JBrowse link
G Mmp1 matrix metallopeptidase 1 multiple interactions
increases expression
EXP ilomastat affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MMP1 protein]; ilomastat inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MMP1 mRNA]
Trinitrobenzenesulfonic Acid results in increased expression of MMP1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of MMP1 protein
CTD PMID:18837084 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Mmp12 matrix metallopeptidase 12 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of MMP12 mRNA CTD PMID:17982090 NCBI chr 8:5,594,717...5,616,494
Ensembl chr 8:5,606,592...5,616,493
JBrowse link
G Mmp14 matrix metallopeptidase 14 multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MMP14 mRNA] CTD PMID:18200517 NCBI chr15:33,074,441...33,083,666
Ensembl chr15:33,074,441...33,083,655
JBrowse link
G Mmp15 matrix metallopeptidase 15 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of MMP15 mRNA CTD PMID:17982090 NCBI chr19:10,079,881...10,101,380
Ensembl chr19:10,079,765...10,101,451
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MMP2 mRNA] CTD PMID:18200517 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions EXP 4-methylesculetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of and results in increased cleavage of MMP9 protein]; Prednisolone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of and results in increased cleavage of MMP9 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of and results in increased cleavage of MMP9 protein]; Trinitrobenzenesulfonic Acid results in increased activity of and results in increased cleavage of MMP9 protein CTD PMID:22119283 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mnda myeloid cell nuclear differentiation antigen increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of IFI204 mRNA
Trinitrobenzenesulfonic Acid results in increased expression of MNDA mRNA
CTD PMID:17982090 NCBI chr13:92,073,664...92,091,335
Ensembl chr13:92,073,668...92,089,980
JBrowse link
G Moxd2 monooxygenase, DBH-like 2 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of MOXD2 mRNA CTD PMID:17982090 NCBI chr 4:69,117,477...69,125,972
Ensembl chr 4:69,117,477...69,125,972
JBrowse link
G Mpo myeloperoxidase multiple interactions
increases activity
increases expression
EXP
ISO
4-methylesculetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; [potassium oxonate co-treated with Inosine Monophosphate] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Cadmium Chloride inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Chalcones inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; cinnamic aldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Ciprofloxacin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Dinoprostone analog inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Genistein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; Heme inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; hesperetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; Indomethacin inhibits the reaction [Smoke promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]]; Indomethacin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Inosine Monophosphate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Iridoid Glycosides inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Isatin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; montelukast inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; N-(3-(aminomethyl)benzyl)acetamidine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; nimesulide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; nitroaspirin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; potassium oxonate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Prednisolone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Resveratrol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Rifampin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; SC 560 promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; SCH 442416 inhibits the reaction [Inosine Monophosphate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]]; Smoke promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Spironolactone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; tin protoporphyrin IX promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; zileuton inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; zinc protoporphyrin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]
17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; 7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; 8-(bis(2-methylphenyl)methyl)-3-phenyl-8-azabicyclo(3.2.1)octan-3-ol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; [cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; [Rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; cholan-2,3,24-tryl-2,3,24-trisulfate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; ginsenoside Re inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Huangqin-Tang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; J 113397 inhibits the reaction [8-(bis(2-methylphenyl)methyl)-3-phenyl-8-azabicyclo(3.2.1)octan-3-ol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]]; lancemaside A inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; morphiceptin analog affects the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; notoginsenoside R1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Plant Extracts inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; resolvin D1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; resolvin D2 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Rifaximin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; RN 1734 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Ruthenium Red inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; sinomenine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; stattic inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]
Trinitrobenzenesulfonic Acid results in increased expression of MPO; Trinitrobenzenesulfonic Acid results in increased expression of MPO protein
CTD PMID:10845656 PMID:10877837 PMID:11137876 PMID:11504810 PMID:11668029 PMID:11698051 PMID:11959675 PMID:16474422 PMID:16804969 PMID:16867261 PMID:17276891 PMID:17292349 PMID:17375077 PMID:17375199 PMID:17553498 PMID:17936198 PMID:17991707 PMID:18288370 PMID:19002562 PMID:19234664 PMID:19597321 PMID:19956958 PMID:20868668 PMID:21070844 PMID:21599020 PMID:21724996 PMID:21893697 PMID:22029500 PMID:22039321 PMID:22119283 PMID:22410118 PMID:22849695 PMID:22882778 PMID:23596210 PMID:24038091 PMID:24066068 PMID:24101390 PMID:24316276 PMID:24345466 PMID:24831514 PMID:25079872 PMID:25149976 PMID:25445197 PMID:25472953 PMID:25526689 PMID:25576893 PMID:25740948 PMID:26165751 PMID:30365937 PMID:30503585 PMID:31428839 PMID:31669340 PMID:33412153 PMID:33522063 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Mrc1 mannose receptor, C type 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of MRC1 mRNA CTD PMID:17982090 NCBI chr17:81,352,700...81,433,743
Ensembl chr17:81,352,700...81,433,743
JBrowse link
G Mrm3 mitochondrial rRNA methyltransferase 3 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of MRM3 mRNA CTD PMID:17982090 NCBI chr10:64,398,308...64,406,193
Ensembl chr10:64,398,339...64,405,017
JBrowse link
G Mrpl47 mitochondrial ribosomal protein L47 multiple interactions
decreases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of MRPL47 mRNA] CTD PMID:18200517 NCBI chr 2:119,128,311...119,139,451
Ensembl chr 2:119,128,309...119,139,451
JBrowse link
G Msn moesin multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MSN mRNA] CTD PMID:18200517 NCBI chr  X:65,226,834...65,294,192
Ensembl chr  X:65,226,748...65,295,810
JBrowse link
G Mtor mechanistic target of rapamycin kinase increases phosphorylation
multiple interactions
EXP Trinitrobenzenesulfonic Acid results in increased phosphorylation of MTOR protein
dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of MTOR protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of MTOR protein]
CTD PMID:33412153 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Muc2 mucin 2, oligomeric mucus/gel-forming multiple interactions
decreases expression
increases expression
EXP
ISO
Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MUC2 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MUC2 mRNA]
Trinitrobenzenesulfonic Acid results in decreased expression of MUC2 mRNA
CTD PMID:17449585 PMID:19998380 PMID:25307695 NCBI chr 1:214,663,929...214,693,197 JBrowse link
G Muc3 mucin 3, intestinal increases expression
multiple interactions
decreases expression
EXP Trinitrobenzenesulfonic Acid results in increased expression of MUC3 mRNA
Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MUC3 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MUC3 mRNA]
Trinitrobenzenesulfonic Acid results in decreased expression of MUC3 mRNA
CTD PMID:17375077 PMID:17449585 NCBI chr12:22,535,663...22,584,775 JBrowse link
G Muc4 mucin 4, cell surface associated multiple interactions
increases expression
EXP Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MUC4 mRNA]; kappa-casein glycomacropeptide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MUC4 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MUC4 mRNA] CTD PMID:15867298 PMID:17449585 NCBI chr11:71,242,973...71,285,217
Ensembl chr11:71,243,334...71,284,939
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor multiple interactions
increases expression
EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MYD88 protein]
Trinitrobenzenesulfonic Acid results in increased expression of MYD88; Trinitrobenzenesulfonic Acid results in increased expression of MYD88 protein
CTD PMID:16891783 PMID:19002562 NCBI chr 8:128,022,512...128,027,462
Ensembl chr 8:128,022,473...128,026,841
JBrowse link
G Naglu N-acetyl-alpha-glucosaminidase increases secretion EXP Trinitrobenzenesulfonic Acid results in increased secretion of NAGLU protein CTD PMID:23307618 NCBI chr10:88,979,363...88,986,879
Ensembl chr10:88,979,383...88,986,867
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions
affects expression
decreases expression
EXP 4-methylesculetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of NFE2L2 mRNA]; dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid affects the expression of NFE2L2 protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid affects the expression of NFE2L2 protein]; Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of NFE2L2 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of NFE2L2 mRNA] CTD PMID:31428839 PMID:31669340 PMID:33412153 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 increases expression
multiple interactions
EXP Trinitrobenzenesulfonic Acid results in increased expression of NFKB1 protein
geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NFKB1 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NFKB1 protein]
CTD PMID:26165751 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions
decreases expression
increases degradation
EXP bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of NFKBIA protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased degradation of NFKBIA protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased degradation of NFKBIA protein] CTD PMID:15793857 PMID:30365937 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Ngf nerve growth factor increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of NGF mRNA CTD PMID:17385238 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions
increases expression
EXP bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NLRP3 protein] CTD PMID:30365937 NCBI chr10:45,884,324...45,918,290
Ensembl chr10:45,893,018...45,918,254
JBrowse link
G Nmt2 N-myristoyltransferase 2 decreases expression
multiple interactions
ISO Trinitrobenzenesulfonic Acid results in decreased expression of NMT2 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of NMT2 mRNA]
CTD PMID:18200517 NCBI chr17:78,919,235...78,966,013
Ensembl chr17:78,921,793...78,962,476
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 increases expression ISO
EXP
Trinitrobenzenesulfonic Acid results in increased expression of NOD2 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of NOD2 protein CTD PMID:16891783 PMID:22147983 NCBI chr19:19,342,061...19,389,366
Ensembl chr19:19,332,594...19,377,492
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
increases activity
increases expression
affects response to substance
ISO
EXP
Minocycline inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]; NOS2 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCN4 mRNA]; seryl-leucyl-isoleucyl-glycyl--arginyl-leucinamide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]; soyasaponin I inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein]
Trinitrobenzenesulfonic Acid results in increased activity of NOS2 protein
Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein
NOS2 protein affects the susceptibility to Trinitrobenzenesulfonic Acid
Alendronate affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein]; Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]; bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]; Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]; kappa-casein glycomacropeptide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein]; Methylene Blue inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of NOS2 protein]; montelukast inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein]; nitroaspirin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]; Sulfasalazine affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of NOS2 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]
CTD PMID:10845656 PMID:11504810 PMID:11698051 PMID:11717450 PMID:15867298 PMID:17276891 PMID:17375077 PMID:17449036 PMID:17982090 PMID:19238344 PMID:19285099 PMID:20923188 PMID:21893697 PMID:22039321 PMID:24831514 PMID:30365937 PMID:30503585 PMID:31428839 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Npy1r neuropeptide Y receptor Y1 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of NPY1R mRNA CTD PMID:23537331 NCBI chr16:24,779,480...24,789,131
Ensembl chr16:24,779,477...24,788,740
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of NQO1 mRNA CTD PMID:19524605 PMID:22609641 PMID:25724174 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of NR1H4 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of NR1H4 protein CTD PMID:21829567 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 decreases expression
multiple interactions
ISO Trinitrobenzenesulfonic Acid results in decreased expression of NR1I2 mRNA
[cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein]; [cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]; [cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; [cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; [rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein]; [rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]; [rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]; [rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]
[cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] which results in decreased susceptibility to Trinitrobenzenesulfonic Acid; [Rifaximin binds to and results in increased activity of NR1I2 protein] which results in decreased susceptibility to Trinitrobenzenesulfonic Acid
CTD PMID:21599020 PMID:21829567 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nr2f1 nuclear receptor subfamily 2, group F, member 1 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of NR2F1 mRNA CTD PMID:23537331 NCBI chr 2:5,569,954...5,579,894
Ensembl chr 2:5,569,935...5,579,894
JBrowse link
G Nts neurotensin multiple interactions ISO NTS protein promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VWF protein] CTD PMID:25307345 NCBI chr 7:44,111,594...44,120,998
Ensembl chr 7:44,111,151...44,121,130
JBrowse link
G Ntsr1 neurotensin receptor 1 multiple interactions
increases response to substance
ISO NTSR1 protein affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VEGFA mRNA]
NTSR1 protein results in increased susceptibility to Trinitrobenzenesulfonic Acid
CTD PMID:25307345 NCBI chr 3:175,982,313...176,046,345
Ensembl chr 3:175,885,894...176,046,345
JBrowse link
G Nucb2 nucleobindin 2 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of NUCB2 mRNA CTD PMID:17982090 NCBI chr 1:185,106,773...185,143,278
Ensembl chr 1:185,104,656...185,143,272
JBrowse link
G Ocln occludin multiple interactions
decreases expression
ISO Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of OCLN mRNA]; ginsenoside Re inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of OCLN protein]
Trinitrobenzenesulfonic Acid results in decreased expression of OCLN mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of OCLN protein
CTD PMID:22147983 PMID:22849695 PMID:25307695 NCBI chr 2:30,527,327...30,577,218
Ensembl chr 2:30,527,715...30,577,218
JBrowse link
G Odc1 ornithine decarboxylase 1 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of ODC1 mRNA CTD PMID:12163651 NCBI chr 6:42,852,529...42,859,142
Ensembl chr 6:42,852,683...42,859,927
JBrowse link
G Olr1684 olfactory receptor 1684 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of OLFR91 mRNA CTD PMID:17982090 NCBI chr20:572,454...573,395
Ensembl chr20:572,454...573,395
JBrowse link
G Olr1750 olfactory receptor 1750 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of OLFR90 mRNA CTD PMID:17982090 NCBI chr20:1,944,849...1,955,249
Ensembl chr20:1,944,801...1,945,844
JBrowse link
G Oprd1 opioid receptor, delta 1 multiple interactions
increases expression
EXP Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of OPRD1 mRNA]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of OPRD1 protein]; qingre zaoshi liangxue fang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of OPRD1 mRNA]; qingre zaoshi liangxue fang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of OPRD1 protein]
Trinitrobenzenesulfonic Acid results in increased expression of OPRD1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of OPRD1 protein
CTD PMID:24637189 NCBI chr 5:150,288,126...150,323,063
Ensembl chr 5:150,288,126...150,323,063
JBrowse link
G Oprl1 opioid related nociceptin receptor 1 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of OPRL1 mRNA CTD PMID:23537331 NCBI chr 3:177,223,779...177,231,663
Ensembl chr 3:177,225,737...177,231,663
JBrowse link
G Osmr oncostatin M receptor multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of OSMR mRNA] CTD PMID:17982090 PMID:18200517 NCBI chr 2:56,107,491...56,163,522
Ensembl chr 2:56,110,777...56,151,531
JBrowse link
G Otud4 OTU deubiquitinase 4 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of OTUD4 mRNA CTD PMID:17982090 NCBI chr19:31,895,753...31,942,509
Ensembl chr19:31,899,087...31,942,180
JBrowse link
G P2rx7 purinergic receptor P2X 7 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of P2RX7 mRNA CTD PMID:23537331 NCBI chr12:39,353,613...39,396,042
Ensembl chr12:39,353,613...39,396,042
JBrowse link
G P2ry1 purinergic receptor P2Y1 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of P2RY1 mRNA CTD PMID:23537331 NCBI chr 2:151,314,818...151,320,312
Ensembl chr 2:151,314,818...151,320,319
JBrowse link
G P2ry13 purinergic receptor P2Y13 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of P2RY13 mRNA CTD PMID:23537331 NCBI chr 2:149,429,648...149,432,864
Ensembl chr 2:149,430,854...149,432,106
JBrowse link
G Pak2 p21 (RAC1) activated kinase 2 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of PAK2 mRNA CTD PMID:23537331 NCBI chr11:72,829,407...72,865,815
Ensembl chr11:72,829,238...72,865,902
Ensembl chr11:72,829,238...72,865,902
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of PCK1 mRNA CTD PMID:17982090 NCBI chr 3:171,213,936...171,219,885
Ensembl chr 3:171,213,936...171,219,871
JBrowse link
G Pcna proliferating cell nuclear antigen increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of PCNA mRNA; Trinitrobenzenesulfonic Acid results in increased expression of PCNA protein CTD PMID:19234664 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of PDIA3 mRNA CTD PMID:17982090 NCBI chr 3:113,376,983...113,400,707
Ensembl chr 3:113,376,983...113,400,707
JBrowse link
G Pdpn podoplanin multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PDPN mRNA] CTD PMID:18200517 NCBI chr 5:161,947,137...161,981,441
Ensembl chr 5:161,947,137...161,981,441
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 increases expression
multiple interactions
EXP Trinitrobenzenesulfonic Acid results in increased expression of PECAM1 protein
Chalcones inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PECAM1 protein]
CTD PMID:22410118 NCBI chr10:94,850,971...94,913,202 JBrowse link
G Pgs1 phosphatidylglycerophosphate synthase 1 multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PGS1 mRNA] CTD PMID:18200517 NCBI chr10:106,994,595...107,030,208
Ensembl chr10:106,991,935...107,030,260
JBrowse link
G Pir pirin increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of PIR mRNA CTD PMID:19524605 PMID:22609641 NCBI chr  X:31,852,322...31,968,152
Ensembl chr  X:31,852,323...31,968,152
JBrowse link
G Pirb paired Ig-like receptor B multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LILRB3 mRNA] CTD PMID:18200517 NCBI chr 1:64,074,097...64,081,568
Ensembl chr 1:64,074,231...64,081,438
JBrowse link
G Pklr pyruvate kinase L/R increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of PKLR mRNA CTD PMID:17982090 NCBI chr 2:188,449,158...188,458,034
Ensembl chr 2:188,449,210...188,459,592
JBrowse link
G Pla2g12a phospholipase A2, group XIIA increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of PLA2G12A mRNA CTD PMID:17982090 NCBI chr 2:235,311,664...235,327,972
Ensembl chr 2:235,311,719...235,327,972
JBrowse link
G Pla2g2a phospholipase A2 group IIA multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PLA2G2A mRNA] CTD PMID:17982090 PMID:18200517 NCBI chr 5:157,282,650...157,285,295
Ensembl chr 5:157,282,669...157,285,328
JBrowse link
G Pla2g7 phospholipase A2 group VII increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of PLA2G7 mRNA CTD PMID:17982090 NCBI chr 9:19,935,754...19,978,013
Ensembl chr 9:19,935,768...19,978,013
JBrowse link
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 increases expression
multiple interactions
ISO Trinitrobenzenesulfonic Acid results in increased expression of PLOD2 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PLOD2 mRNA]
CTD PMID:18200517 NCBI chr 8:99,977,334...100,059,736
Ensembl chr 8:99,977,334...100,059,736
JBrowse link
G Pnliprp1 pancreatic lipase-related protein 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of PNLIPRP1 mRNA CTD PMID:17982090 NCBI chr 1:279,867,034...279,882,663
Ensembl chr 1:279,867,034...279,882,663
JBrowse link
G Pomc proopiomelanocortin decreases expression
increases expression
ISO
EXP
Trinitrobenzenesulfonic Acid results in decreased expression of POMC mRNA
Trinitrobenzenesulfonic Acid results in increased expression of POMC protein
CTD PMID:11959675 PMID:25307695 NCBI chr 6:28,382,937...28,388,771
Ensembl chr 6:28,382,962...28,388,967
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions
decreases expression
EXP
ISO
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG protein]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG mRNA]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG protein]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG mRNA]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG mRNA]
Trinitrobenzenesulfonic Acid results in decreased expression of PPARG mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of PPARG protein
CTD PMID:16782535 PMID:19617644 PMID:21829567 PMID:24831514 PMID:26165751 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Prkci protein kinase C, iota increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of PRKCI mRNA CTD PMID:23537331 NCBI chr 2:115,941,998...116,002,550
Ensembl chr 2:115,941,993...116,002,561
JBrowse link
G Prss1 serine protease 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of PRSS1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of TRY10 mRNA CTD PMID:17982090 NCBI chr 4:70,776,046...70,779,249
Ensembl chr 4:70,776,046...70,779,249
JBrowse link
G Prss3 serine protease 3 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of PRSS3 mRNA CTD PMID:17982090 NCBI chr 4:70,614,524...70,617,998
Ensembl chr 4:70,614,524...70,617,998
JBrowse link
G Psme3 proteasome activator subunit 3 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of PSME3 mRNA CTD PMID:17982090 NCBI chr10:89,236,256...89,244,041
Ensembl chr10:89,236,256...89,244,041
JBrowse link
G Ptger2 prostaglandin E receptor 2 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of PTGER2 mRNA CTD PMID:23537331 PMID:25526689 NCBI chr15:19,336,029...19,349,759
Ensembl chr15:19,338,175...19,350,210
JBrowse link
G Ptger4 prostaglandin E receptor 4 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of PTGER4 mRNA CTD PMID:25526689 NCBI chr 2:54,951,625...54,966,470
Ensembl chr 2:54,952,821...54,963,448
JBrowse link
G Ptges prostaglandin E synthase increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of PTGES mRNA CTD PMID:25526689 NCBI chr 3:9,727,408...9,738,752
Ensembl chr 3:9,727,408...9,738,752
JBrowse link
G Ptgir prostaglandin I2 receptor increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of PTGIR mRNA CTD PMID:25526689 NCBI chr 1:78,833,449...78,835,832
Ensembl chr 1:78,833,157...78,837,623
JBrowse link
G Ptgis prostaglandin I2 synthase increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of PTGIS mRNA CTD PMID:25526689 NCBI chr 3:163,950,746...163,986,129 JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of PTGS1 mRNA CTD PMID:25526689 NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
decreases expression
increases expression
ISO
EXP
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; Huangqin-Tang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; lancemaside A inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; seryl-leucyl-isoleucyl-glycyl--arginyl-leucinamide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; soyasaponin I inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]
Trinitrobenzenesulfonic Acid results in decreased expression of PTGS2 mRNA
Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein
Trinitrobenzenesulfonic Acid results in increased expression of PTGS2; Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein
Alendronate affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; Genistein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; Genistein inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; Isatin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2]; nitroaspirin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; Resveratrol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; Smoke promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; Smoke promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]
CTD PMID:11137876 PMID:11698051 PMID:11717450 PMID:11820457 PMID:15973123 PMID:16474422 PMID:16782535 PMID:16804969 PMID:17276891 PMID:17375077 PMID:17375199 PMID:18200517 PMID:19234664 PMID:19956958 PMID:20923188 PMID:21513799 PMID:21893697 PMID:22039321 PMID:24316276 PMID:24831514 PMID:25307695 PMID:25526689 PMID:25576893 PMID:30365937 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of PTPRC mRNA CTD PMID:17982090 NCBI chr13:55,061,561...55,174,150
Ensembl chr13:55,061,562...55,173,692
JBrowse link
G Ptpro protein tyrosine phosphatase, receptor type, O multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTPRO mRNA] CTD PMID:18200517 NCBI chr 4:171,250,766...171,461,571
Ensembl chr 4:171,250,818...171,461,677
JBrowse link
G Ptx3 pentraxin 3 increases expression
multiple interactions
ISO Trinitrobenzenesulfonic Acid results in increased expression of PTX3 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTX3 mRNA]
CTD PMID:18200517 NCBI chr 2:158,097,843...158,103,653
Ensembl chr 2:158,097,843...158,103,653
JBrowse link
G Rab10 RAB10, member RAS oncogene family decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of RAB10 mRNA CTD PMID:23537331 NCBI chr 6:27,668,387...27,721,120
Ensembl chr 6:27,668,403...27,721,120
JBrowse link
G Rab15 RAB15, member RAS oncogene family increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of RAB15 mRNA CTD PMID:23537331 NCBI chr 6:99,845,952...99,870,320
Ensembl chr 6:99,845,954...99,870,024
JBrowse link
G Rab39a RAB39A, member RAS oncogene family increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of RAB39A mRNA CTD PMID:23537331 NCBI chr 8:58,275,984...58,292,995
Ensembl chr 8:58,272,098...58,293,102
JBrowse link
G Rab5a RAB5A, member RAS oncogene family increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of RAB5A mRNA CTD PMID:23537331 NCBI chr 9:5,910...6,065 JBrowse link
G Ramp2 receptor activity modifying protein 2 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of RAMP2 mRNA CTD PMID:21808981 NCBI chr10:89,166,170...89,168,962
Ensembl chr10:89,166,890...89,168,965
JBrowse link
G Ramp3 receptor activity modifying protein 3 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of RAMP3 mRNA CTD PMID:21808981 NCBI chr14:86,922,223...86,939,722
Ensembl chr14:86,922,223...86,939,719
JBrowse link
G Rap1b RAP1B, member of RAS oncogene family increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of RAP1B mRNA CTD PMID:23537331 NCBI chr 7:60,850,406...60,878,226
Ensembl chr 7:60,853,930...60,860,990
JBrowse link
G Rasa2 RAS p21 protein activator 2 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of RASA2 mRNA CTD PMID:23537331 NCBI chr 8:104,417,827...104,542,313
Ensembl chr 8:104,414,567...104,542,317
JBrowse link
G Rasa3 RAS p21 protein activator 3 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of RASA3 mRNA CTD PMID:23537331 NCBI chr16:81,320,090...81,434,239
Ensembl chr16:81,318,633...81,434,363
JBrowse link
G Rasd2 RASD family, member 2 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of RASD2 mRNA CTD PMID:23537331 NCBI chr19:14,653,198...14,663,914
Ensembl chr19:14,653,198...14,663,914
JBrowse link
G Rbp1 retinol binding protein 1 multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RBP1 mRNA] CTD PMID:17982090 PMID:18200517 NCBI chr 8:106,449,321...106,470,842
Ensembl chr 8:106,449,321...106,470,842
JBrowse link
G Reg3b regenerating family member 3 beta increases expression
multiple interactions
ISO Trinitrobenzenesulfonic Acid results in increased expression of REG3A mRNA; Trinitrobenzenesulfonic Acid results in increased expression of REG3B mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of REG3A mRNA]
CTD PMID:17982090 PMID:18200517 NCBI chr 4:109,467,272...109,470,510
Ensembl chr 4:109,467,272...109,470,510
JBrowse link
G Reg3g regenerating family member 3 gamma multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of REG3G mRNA] CTD PMID:17982090 PMID:18200517 NCBI chr 4:109,529,679...109,532,234
Ensembl chr 4:109,529,679...109,532,234
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
increases phosphorylation
increases expression
affects localization
EXP
ISO
Chalcones inhibits the reaction [Trinitrobenzenesulfonic Acid affects the localization of RELA protein]; dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of RELA protein]; Iridoid Glycosides inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RELA mRNA]; Iridoid Glycosides inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RELA protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of RELA protein]; Resveratrol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RELA protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RELA mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RELA protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RELA mRNA]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RELA protein]
Trinitrobenzenesulfonic Acid results in increased expression of RELA mRNA; Trinitrobenzenesulfonic Acid results in increased expression of RELA protein
lancemaside A inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of RELA protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of RELA protein]
CTD PMID:16474422 PMID:19597321 PMID:19956958 PMID:21070844 PMID:22410118 PMID:24831514 PMID:33412153 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Retnlb resistin like beta increases expression
multiple interactions
ISO Trinitrobenzenesulfonic Acid results in increased expression of RETNLB mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RETNLB mRNA]
CTD PMID:18200517 NCBI chr11:54,565,471...54,567,578
Ensembl chr11:54,565,472...54,567,357
JBrowse link
G Rhoq ras homolog family member Q increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of RHOQ mRNA CTD PMID:23537331 NCBI chr 6:10,533,151...10,568,582
Ensembl chr 6:10,533,151...10,568,581
JBrowse link
G Rmnd1 required for meiotic nuclear division 1 homolog decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of RMND1 mRNA CTD PMID:17982090 NCBI chr 1:40,948,843...40,982,669
Ensembl chr 1:40,948,847...40,972,826
JBrowse link
G Rnase1l1 ribonuclease, RNase A family, 1-like 1 (pancreatic) increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of RNASE1 mRNA CTD PMID:17982090 NCBI chr15:28,043,491...28,045,098
Ensembl chr15:28,043,758...28,044,210
JBrowse link
G Rngtt RNA guanylyltransferase and 5'-phosphatase increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of RNGTT mRNA CTD PMID:17982090 NCBI chr 5:48,561,325...48,779,214
Ensembl chr 5:48,561,339...48,779,207
JBrowse link
G Rprm reprimo, TP53 dependent G2 arrest mediator homolog decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of RPRM mRNA CTD PMID:17982090 NCBI chr 3:39,595,301...39,596,718
Ensembl chr 3:39,595,301...39,596,718
JBrowse link
G Rreb1 ras responsive element binding protein 1 multiple interactions
decreases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of RREB1 mRNA] CTD PMID:18200517 NCBI chr17:27,539,137...27,718,878
Ensembl chr17:27,539,133...27,665,266
JBrowse link
G RT1-Ba RT1 class II, locus Ba increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of H2-AA mRNA CTD PMID:17982090 NCBI chr20:4,066,133...4,070,726
Ensembl chr20:4,066,132...4,070,721
JBrowse link
G RT1-Da RT1 class II, locus Da increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of H2-EA mRNA CTD PMID:17982090 NCBI chr20:4,127,644...4,132,616
Ensembl chr20:4,127,644...4,132,616
JBrowse link
G Ryr1 ryanodine receptor 1 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of RYR1 mRNA CTD PMID:23537331 NCBI chr 1:87,959,596...88,066,252
Ensembl chr 1:87,959,712...88,066,101
JBrowse link
G S100a8 S100 calcium binding protein A8 multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of S100A8 mRNA] CTD PMID:17982090 PMID:18200517 NCBI chr 2:190,073,239...190,074,333
Ensembl chr 2:190,073,815...190,074,354
JBrowse link
G S100a9 S100 calcium binding protein A9 multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of S100A9 mRNA] CTD PMID:17982090 PMID:18200517 NCBI chr 2:190,097,436...190,100,209
Ensembl chr 2:190,097,554...190,100,276
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of SAT1 mRNA CTD PMID:12163651 NCBI chr  X:43,626,480...43,629,767
Ensembl chr  X:43,625,169...43,629,765
JBrowse link
G Scd stearoyl-CoA desaturase increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of SCD1 mRNA CTD PMID:17982090 NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
JBrowse link
G Scn10a sodium voltage-gated channel alpha subunit 10 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of SCN10A CTD PMID:15205116 NCBI chr 8:128,298,593...128,416,896
Ensembl chr 8:128,298,594...128,416,650
JBrowse link
G Selenow selenoprotein W increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of SELENOW mRNA CTD PMID:17982090 NCBI chr 1:77,530,692...77,535,765
Ensembl chr 1:77,533,148...77,535,681
Ensembl chr 1:77,533,148...77,535,681
JBrowse link
G Serpina3m serpin family A member 3M increases expression
multiple interactions
ISO Trinitrobenzenesulfonic Acid results in increased expression of SERPINA3 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SERPINA3 mRNA]
CTD PMID:18200517 NCBI chr 6:127,808,785...127,816,067
Ensembl chr 6:127,808,785...127,816,055
JBrowse link
G Serpinb5 serpin family B member 5 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of SERPINB5 mRNA CTD PMID:17982090 NCBI chr13:26,903,052...26,923,250
Ensembl chr13:26,903,052...26,923,250
JBrowse link
G Serpine2 serpin family E member 2 multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SERPINE2 mRNA] CTD PMID:18200517 NCBI chr 9:85,560,852...85,629,410
Ensembl chr 9:85,560,863...85,626,094
JBrowse link
G Shbg sex hormone binding globulin increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of SHBG mRNA CTD PMID:17982090 NCBI chr10:56,219,861...56,237,354
Ensembl chr10:56,219,858...56,223,245
JBrowse link
G Sirt1 sirtuin 1 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of SIRT1 protein CTD PMID:24782617 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Slc10a1 solute carrier family 10 member 1 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of SLC10A1 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of SLC10A1 protein CTD PMID:12044520 NCBI chr 6:104,617,730...104,631,355
Ensembl chr 6:104,617,730...104,631,355
JBrowse link
G Slc1a1 solute carrier family 1 member 1 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of SLC1A1 mRNA CTD PMID:17982090 NCBI chr 1:246,955,017...247,035,159
Ensembl chr 1:246,954,980...247,037,056
JBrowse link
G Slc20a1 solute carrier family 20 member 1 multiple interactions
decreases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of SLC20A1 mRNA] CTD PMID:17982090 PMID:18200517 NCBI chr 3:121,725,204...121,739,160
Ensembl chr 3:121,725,859...121,739,173
JBrowse link
G Slc26a2 solute carrier family 26 member 2 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of SLC26A2 mRNA CTD PMID:17982090 NCBI chr18:56,518,999...56,534,539
Ensembl chr18:56,520,740...56,534,415
JBrowse link
G Slc30a10 solute carrier family 30, member 10 decreases expression
multiple interactions
ISO Trinitrobenzenesulfonic Acid results in decreased expression of SLC30A10 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of SLC30A10 mRNA]
CTD PMID:18200517 NCBI chr13:103,396,295...103,406,759
Ensembl chr13:103,396,314...103,410,363
JBrowse link
G Slc4a4 solute carrier family 4 member 4 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of SLC4A4 mRNA CTD PMID:17982090 NCBI chr14:20,476,258...20,817,042
Ensembl chr14:20,479,323...20,920,286
JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of SLCO1A4 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of SLCO1A4 protein CTD PMID:12044520 NCBI chr 4:175,969,549...176,026,227
Ensembl chr 4:175,969,549...176,026,163
JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of SLCO1B2 mRNA CTD PMID:12044520 NCBI chr 4:175,814,118...175,881,775
Ensembl chr 4:175,814,118...175,881,768
JBrowse link
G Slfn4 schlafen family member 4 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of SLFN4 mRNA CTD PMID:17982090 NCBI chr10:70,411,686...70,435,162
Ensembl chr10:70,411,738...70,435,156
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SLPI mRNA] CTD PMID:18200517 NCBI chr 3:160,799,979...160,802,228
Ensembl chr 3:160,799,981...160,802,433
JBrowse link
G Smc2 structural maintenance of chromosomes 2 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of SMC2 mRNA CTD PMID:17982090 NCBI chr 5:68,717,509...68,764,080
Ensembl chr 5:68,717,519...68,763,850
JBrowse link
G Smpx small muscle protein, X-linked multiple interactions
decreases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of SMPX mRNA] CTD PMID:18200517 NCBI chr  X:40,029,200...40,086,870
Ensembl chr  X:40,030,248...40,086,870
JBrowse link
G Socs3 suppressor of cytokine signaling 3 decreases expression
multiple interactions
EXP Trinitrobenzenesulfonic Acid results in decreased expression of SOCS3 protein
cinnamic aldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of SOCS3 protein]; hesperetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of SOCS3 protein]
CTD PMID:33522063 NCBI chr10:106,973,863...106,976,969
Ensembl chr10:106,975,178...106,976,040
JBrowse link
G Sparc secreted protein acidic and cysteine rich multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SPARC mRNA]; Indomethacin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SPARC mRNA]; Tretinoin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SPARC mRNA] CTD PMID:17994277 PMID:18200517 NCBI chr10:40,742,390...40,764,232
Ensembl chr10:40,742,400...40,764,185
JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression
multiple interactions
ISO Trinitrobenzenesulfonic Acid results in increased expression of SPP1 mRNA
Trinitrobenzenesulfonic Acid promotes the reaction [SPP1 protein results in increased susceptibility to Dinitrofluorobenzene]
CTD PMID:14555839 PMID:17982090 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Sqstm1 sequestosome 1 multiple interactions
increases expression
EXP dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SQSTM1 protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SQSTM1 protein] CTD PMID:33412153 NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
JBrowse link
G Srgn serglycin increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of SRGN mRNA CTD PMID:17982090 NCBI chr20:32,120,317...32,158,071
Ensembl chr20:32,120,320...32,139,789
JBrowse link
G Srm spermidine synthase multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SRM mRNA] CTD PMID:18200517 NCBI chr 5:165,405,168...165,408,325
Ensembl chr 5:165,405,168...165,408,320
Ensembl chr 3:165,405,168...165,408,320
JBrowse link
G Stat1 signal transducer and activator of transcription 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of STAT1 mRNA CTD PMID:17982090 NCBI chr 9:54,287,540...54,327,958
Ensembl chr 9:54,287,541...54,484,533
JBrowse link
G Stat3 signal transducer and activator of transcription 3 increases phosphorylation
multiple interactions
ISO
EXP
Trinitrobenzenesulfonic Acid results in increased phosphorylation of STAT3 protein
bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of STAT3 protein]; cinnamic aldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of STAT3 protein]; hesperetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of STAT3 protein]
stattic inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of STAT3 protein]
CTD PMID:25740948 PMID:30365937 PMID:33522063 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Stim1 stromal interaction molecule 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of STIM1 mRNA CTD PMID:17982090 NCBI chr 1:167,373,894...167,533,412
Ensembl chr 1:167,373,678...167,533,420
JBrowse link
G Stk17b serine/threonine kinase 17b increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of STK17B mRNA CTD PMID:23537331 NCBI chr 9:60,399,261...60,430,081
Ensembl chr 9:60,399,261...60,430,081
JBrowse link
G Sulf2 sulfatase 2 multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SULF2 mRNA] CTD PMID:18200517 NCBI chr 3:162,791,349...162,872,984
Ensembl chr 3:162,791,355...162,872,831
JBrowse link
G Tac1 tachykinin, precursor 1 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of TAC1 mRNA CTD PMID:17982090 NCBI chr 4:33,638,853...33,646,819
Ensembl chr 4:33,638,709...33,646,819
JBrowse link
G Tacr1 tachykinin receptor 1 multiple interactions
affects response to substance
ISO TACR1 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL1A2 mRNA]; TACR1 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IGF1 protein]; TACR1 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TGFB1 protein]; TACR1 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VIM mRNA]
TACR1 protein affects the susceptibility to Trinitrobenzenesulfonic Acid
CTD PMID:20889569 NCBI chr 4:113,247,236...113,416,139
Ensembl chr 4:113,247,795...113,414,504
JBrowse link
G Tff3 trefoil factor 3 multiple interactions
increases expression
EXP Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TFF3 mRNA]; kappa-casein glycomacropeptide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TFF3 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TFF3 mRNA] CTD PMID:15867298 PMID:17449585 NCBI chr20:9,850,800...9,855,481
Ensembl chr20:9,850,803...9,855,481
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions
increases expression
decreases expression
ISO 6-diphenylmethyl-5-(5-isopropyl-2-methoxybenzylamino)-1-azabicyclo(2.2.2)octane-3-carboxylic acid inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TGFB1 protein]; [rifaximin co-treated with Trinitrobenzenesulfonic Acid] results in increased expression of TGFB1 protein; stattic inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TGFB1 mRNA]; TACR1 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TGFB1 protein]
Trinitrobenzenesulfonic Acid results in increased expression of TGFB1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of TGFB1 protein
Trinitrobenzenesulfonic Acid results in decreased expression of TGFB1 mRNA
CTD PMID:20889569 PMID:21599020 PMID:25307695 PMID:25740948 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tgfb2 transforming growth factor, beta 2 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of TGFB2 mRNA CTD PMID:25307695 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of TGFBR1 mRNA CTD PMID:23537331 NCBI chr 5:63,056,071...63,119,635
Ensembl chr 5:63,050,758...63,119,635
JBrowse link
G Tgm2 transglutaminase 2 multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TGM2 mRNA] CTD PMID:18200517 NCBI chr 3:154,597,165...154,627,257
Ensembl chr 3:154,597,168...154,627,257
JBrowse link
G Tgm3 transglutaminase 3 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of TGM3 mRNA CTD PMID:17982090 NCBI chr 3:122,544,783...122,580,836
Ensembl chr 3:122,544,788...122,580,905
JBrowse link
G Thbd thrombomodulin increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of THBD mRNA CTD PMID:17982090 NCBI chr 3:142,748,673...142,752,325
Ensembl chr 3:142,748,674...142,752,325
JBrowse link
G Thbs1 thrombospondin 1 multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of THBS1 mRNA] CTD PMID:18200517 NCBI chr 3:109,862,120...109,873,466
Ensembl chr 3:109,862,117...109,873,466
JBrowse link
G Thy1 Thy-1 cell surface antigen increases expression
multiple interactions
ISO Trinitrobenzenesulfonic Acid results in increased expression of THY1 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of THY1 mRNA]
CTD PMID:18200517 NCBI chr 8:48,382,121...48,387,271
Ensembl chr 8:48,382,121...48,386,935
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions
increases expression
ISO
EXP
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TIMP1 mRNA]
Trinitrobenzenesulfonic Acid results in increased expression of TIMP1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of TIMP1 protein
ilomastat affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TIMP1 mRNA]; ilomastat affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TIMP1 protein]
CTD PMID:17982090 PMID:18200517 PMID:18837084 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Tjp1 tight junction protein 1 multiple interactions
decreases expression
ISO ginsenoside Re inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TJP1 protein]
Trinitrobenzenesulfonic Acid results in decreased expression of TJP1 mRNA; Trinitrobenzenesulfonic Acid results in decreased expression of TJP1 protein
CTD PMID:22147983 PMID:22849695 NCBI chr 1:126,146,489...126,515,359
Ensembl chr 1:126,146,489...126,227,469
JBrowse link
G Tjp2 tight junction protein 2 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of TJP2 mRNA CTD PMID:25307695 NCBI chr 1:241,945,816...242,084,044
Ensembl chr 1:241,945,841...242,083,484
JBrowse link
G Tlr2 toll-like receptor 2 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of TLR2 CTD PMID:16891783 NCBI chr 2:182,840,171...182,846,061
Ensembl chr 2:182,840,727...182,846,061
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions
increases expression
decreases expression
ISO
EXP
lancemaside A inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TLR4 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TLR4 protein]
Trinitrobenzenesulfonic Acid results in increased expression of TLR4; Trinitrobenzenesulfonic Acid results in increased expression of TLR4 protein
Trinitrobenzenesulfonic Acid results in decreased expression of TLR4 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TLR4 protein]
CTD PMID:16891783 PMID:19002562 PMID:19597321 PMID:19956958 PMID:19998380 PMID:20136961 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tmem245 transmembrane protein 245 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of TMEM245 mRNA CTD PMID:12163651 NCBI chr 5:73,909,032...73,986,602
Ensembl chr 5:73,918,747...73,986,373
JBrowse link
G Tnc tenascin C multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNC mRNA] CTD PMID:18200517 NCBI chr 5:79,789,686...79,874,555
Ensembl chr 5:79,789,671...79,874,671
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
increases secretion
ISO
EXP
[cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; [Rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; cholan-2,3,24-tryl-2,3,24-trisulfate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; dai-kenchu-to inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF]; Huangqin-Tang inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; icilin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; lancemaside A inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Minocycline inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; notoginsenoside R1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Rifaximin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; seryl-leucyl-isoleucyl-glycyl--arginyl-leucinamide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; sinomenine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; sinomenine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; soyasaponin Ab inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; soyasaponin I inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]
Trinitrobenzenesulfonic Acid results in increased expression of TNF; Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA; Trinitrobenzenesulfonic Acid results in increased expression of TNF protein
Trinitrobenzenesulfonic Acid results in increased secretion of TNF protein
4-methylesculetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; [allicin co-treated with Mesalamine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; [allicin co-treated with Sulfasalazine] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; [Inosine Monophosphate co-treated with potassium oxonate] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased secretion of TNF protein]; allicin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]]; Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Chalcones inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; cinnamic aldehyde inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Dexamethasone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Dinoprostone analog inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; hesperetin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; iberogast inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Inosine Monophosphate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Iridoid Glycosides inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Isatin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; nitroaspirin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; potassium oxonate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Prednisolone inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Resveratrol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; SC 560 promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; SCH 442416 inhibits the reaction [Inosine Monophosphate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased secretion of TNF protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]
CTD PMID:11717450 PMID:12717850 PMID:16474422 PMID:16782535 PMID:16867261 PMID:17276891 PMID:17375199 PMID:17449585 PMID:18200517 PMID:19196500 PMID:19285099 PMID:19597321 PMID:19956958 PMID:19998380 PMID:20136961 PMID:20868668 PMID:20923188 PMID:21070844 PMID:21122500 PMID:21513799 PMID:21599020 PMID:21829567 PMID:21893697 PMID:22039321 PMID:22060784 PMID:22119283 PMID:22147983 PMID:22410118 PMID:22427801 PMID:23027085 PMID:23537331 PMID:23596210 PMID:23747339 PMID:24066068 PMID:24316276 PMID:24831514 PMID:25472953 PMID:25576893 PMID:25727887 PMID:25729217 PMID:27783946 PMID:30503585 PMID:33412153 PMID:33522063 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf25 TNF receptor superfamily member 25 increases response to substance ISO TNFRSF25 protein results in increased susceptibility to Trinitrobenzenesulfonic Acid CTD PMID:20980995 NCBI chr 5:169,288,419...169,293,137
Ensembl chr 5:169,288,871...169,293,137
JBrowse link
G Tnfsf11 TNF superfamily member 11 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of TNFSF11 protein CTD PMID:23747339 NCBI chr15:60,482,527...60,512,704
Ensembl chr15:60,482,527...60,512,704
JBrowse link
G Tnfsf15 TNF superfamily member 15 increases response to substance ISO TNFSF15 protein results in increased susceptibility to Trinitrobenzenesulfonic Acid CTD PMID:20980995 NCBI chr 5:79,553,935...79,569,974
Ensembl chr 5:79,553,742...79,570,073
JBrowse link
G Tnfsf4 TNF superfamily member 4 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of TNFSF4 mRNA CTD PMID:23537331 NCBI chr13:79,269,973...79,293,775
Ensembl chr13:79,269,973...79,293,778
JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases expression
ISO
EXP
D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of TRP53 protein]
Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of and results in increased activity of TP53 protein]; Trinitrobenzenesulfonic Acid results in increased phosphorylation of and results in increased activity of TP53 protein
Trinitrobenzenesulfonic Acid results in increased expression of TRP53 protein
CTD PMID:22427801 PMID:30503585 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Trim15 tripartite motif containing 15 multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TRIM15 mRNA] CTD PMID:18200517 NCBI chr20:2,194,293...2,203,636
Ensembl chr20:2,194,709...2,201,668
JBrowse link
G Trim16 tripartite motif-containing 16 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of TRIM16 mRNA CTD PMID:19524605 PMID:22609641 NCBI chr10:49,231,660...49,254,653
Ensembl chr10:49,231,730...49,254,621
JBrowse link
G Trip4 thyroid hormone receptor interactor 4 increases expression
multiple interactions
EXP Trinitrobenzenesulfonic Acid results in increased expression of TRIP4 protein
bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TRIP4 protein]
CTD PMID:30365937 NCBI chr 8:71,369,121...71,533,281
Ensembl chr 8:71,371,370...71,533,459
JBrowse link
G Trpc3 transient receptor potential cation channel, subfamily C, member 3 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of TRPC3 mRNA CTD PMID:23537331 NCBI chr 2:123,329,954...123,467,574
Ensembl chr 2:123,329,875...123,407,496
JBrowse link
G Trpm8 transient receptor potential cation channel, subfamily M, member 8 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of TRPM8 mRNA CTD PMID:23596210 NCBI chr 9:95,393,370...95,484,528
Ensembl chr 9:95,398,237...95,482,890
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions
increases expression
decreases expression
EXP topiramate inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TRPV1 mRNA]
Trinitrobenzenesulfonic Acid results in increased expression of TRPV1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of TRPV1 protein
CTD PMID:17698068 PMID:17991707 PMID:21849664 PMID:25445197 NCBI chr10:59,799,123...59,824,208
Ensembl chr10:59,799,123...59,824,679
JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of TRPV4 mRNA CTD PMID:22882778 NCBI chr12:47,698,915...47,737,902
Ensembl chr12:47,698,947...47,737,902
JBrowse link
G Trpv5 transient receptor potential cation channel, subfamily V, member 5 multiple interactions ISO KL protein inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TRPV5 protein]; Trinitrobenzenesulfonic Acid results in decreased expression of and results in increased metabolism of TRPV5 protein CTD PMID:23747339 NCBI chr 4:70,947,615...70,974,004
Ensembl chr 4:70,947,717...70,974,006
JBrowse link
G Txndc16 thioredoxin domain containing 16 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of TXNDC16 mRNA CTD PMID:17982090 NCBI chr15:19,472,522...19,547,384
Ensembl chr15:19,473,373...19,541,815
JBrowse link
G Tyrobp transmembrane immune signaling adaptor Tyrobp multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TYROBP mRNA] CTD PMID:17982090 PMID:18200517 NCBI chr 1:88,875,370...88,879,305
Ensembl chr 1:88,875,375...88,879,303
JBrowse link
G Ubc ubiquitin C increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of UBC mRNA CTD PMID:12163651 NCBI chr12:36,638,457...36,642,734
Ensembl chr12:36,638,457...36,642,734
JBrowse link
G Ubd ubiquitin D increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of UBD mRNA CTD PMID:17982090 NCBI chr20:1,876,175...1,878,126
Ensembl chr20:1,876,173...1,897,814
JBrowse link
G Ube2w ubiquitin-conjugating enzyme E2W decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of UBE2W mRNA CTD PMID:17982090 NCBI chr 5:29,798,845...29,812,777 JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of UGT1A6 mRNA CTD PMID:12163651 NCBI chr 9:95,241,609...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Usp8 ubiquitin specific peptidase 8 decreases expression EXP Trinitrobenzenesulfonic Acid results in decreased expression of USP8 mRNA CTD PMID:23537331 NCBI chr 3:119,173,818...119,222,499
Ensembl chr 3:119,173,818...119,222,484
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 increases expression
multiple interactions
ISO
EXP
Trinitrobenzenesulfonic Acid results in increased expression of VCAM1 mRNA
Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VCAM1 mRNA]; Resveratrol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VCAM1 protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VCAM1 mRNA]
Trinitrobenzenesulfonic Acid results in increased expression of VCAM1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of VCAM1 protein
CTD PMID:17982090 PMID:22029500 PMID:30503585 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
JBrowse link
G Vcan versican multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VCAN mRNA] CTD PMID:18200517 NCBI chr 2:18,490,102...18,587,340
Ensembl chr 2:18,490,102...18,565,842
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions
increases expression
EXP
ISO
Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VEGFA mRNA]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VEGFA mRNA]]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VEGFA mRNA]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VEGFA mRNA]
NTSR1 protein affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VEGFA mRNA]
CTD PMID:21893697 PMID:25307345 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Vim vimentin multiple interactions
increases expression
ISO 6-diphenylmethyl-5-(5-isopropyl-2-methoxybenzylamino)-1-azabicyclo(2.2.2)octane-3-carboxylic acid inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VIM mRNA]; TACR1 gene mutant form inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VIM mRNA] CTD PMID:20889569 NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212
JBrowse link
G Vnn1 vanin 1 increases expression EXP Trinitrobenzenesulfonic Acid results in increased expression of VNN1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of VNN1 protein CTD PMID:23307618 NCBI chr 1:22,614,832...22,625,134
Ensembl chr 1:22,614,783...22,625,204
JBrowse link
G Vwf von Willebrand factor multiple interactions
increases expression
ISO NTS protein promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VWF protein] CTD PMID:25307345 NCBI chr 4:158,085,059...158,219,525
Ensembl chr 4:158,088,505...158,219,523
JBrowse link
G Wdr48 WD repeat domain 48 decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of WDR48 mRNA CTD PMID:17982090 NCBI chr 8:128,577,080...128,610,287
Ensembl chr 8:128,577,080...128,610,287
JBrowse link
G Wfdc18 WAP four-disulfide core domain 18 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of WFDC18 mRNA CTD PMID:17982090 NCBI chr10:71,008,709...71,010,863
Ensembl chr10:71,008,709...71,010,863
JBrowse link
G Zc3h11a zinc finger CCCH-type containing 11A decreases expression ISO Trinitrobenzenesulfonic Acid results in decreased expression of ZC3H11A mRNA CTD PMID:17982090 NCBI chr13:50,196,042...50,234,862
Ensembl chr13:50,196,042...50,234,862
JBrowse link
G Zfp36l2 zinc finger protein 36, C3H type-like 2 increases expression ISO Trinitrobenzenesulfonic Acid results in increased expression of ZFP36L2 mRNA CTD PMID:17982090 NCBI chr 6:7,417,416...7,423,447
Ensembl chr 6:7,417,425...7,421,456
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19786
    role 19732
      application 19423
        reagent 17244
          2,4,6-trinitrobenzenesulfonic acid 430
Path 2
Term Annotations click to browse term
  CHEBI ontology 19786
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19675
                    p-block element atom 19675
                      chalcogen 19413
                        oxygen atom 19378
                          oxygen molecular entity 19378
                            hydroxides 19103
                              oxoacid 18350
                                chalcogen oxoacid 11503
                                  sulfur oxoacid 11111
                                    sulfonic acid 7371
                                      sulfo group 5771
                                        organosulfonic acid 5771
                                          arenesulfonic acid 680
                                            2,4,6-trinitrobenzenesulfonic acid 430
paths to the root