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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Geniposide pentaacetate
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Accession:CHEBI:5300 term browser browse the term
Definition:A terpene glycoside that has formula C27H34O15.
Synonyms:related_synonym: Formula=C27H34O15;   InChI=1S/C27H34O15/c1-12(28)35-9-17-7-8-18-19(25(33)34-6)10-37-26(21(17)18)42-27-24(40-16(5)32)23(39-15(4)31)22(38-14(3)30)20(41-27)11-36-13(2)29/h7,10,18,20-24,26-27H,8-9,11H2,1-6H3/t18-,20-,21-,22-,23+,24-,26+,27+/m1/s1;   InChIKey=LKXMXUPYWQQHNY-JPGAYEHLSA-N;   Pentaacetyl geniposide;   SMILES=COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]2OC(C)=O)[C@H]2[C@@H]1CC=C2COC(C)=O
 xref: CAS:49776-64-9;   KEGG:C11639
 xref_mesh: MESH:C074968


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Geniposide pentaacetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions
increases expression		 EXP Masoprocol inhibits the reaction [pentaacetyl geniposide results in increased cleavage of and results in increased activity of CASP3 protein]; Masoprocol inhibits the reaction [pentaacetyl geniposide results in increased expression of CASP3 protein]; pentaacetyl geniposide results in increased cleavage of and results in increased activity of CASP3 protein CTD PMID:17651887 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Faslg Fas ligand increases expression
multiple interactions		 EXP pentaacetyl geniposide results in increased expression of FASLG protein
Masoprocol inhibits the reaction [pentaacetyl geniposide results in increased expression of FASLG protein]		 CTD PMID:17651887 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases phosphorylation
decreases expression		 EXP pentaacetyl geniposide results in increased phosphorylation of FOS protein
pentaacetyl geniposide results in decreased expression of FOS protein		 CTD PMID:17651887 PMID:19464279 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit decreases expression
increases phosphorylation		 EXP pentaacetyl geniposide results in decreased expression of JUN protein
pentaacetyl geniposide results in increased phosphorylation of JUN protein		 CTD PMID:17651887 PMID:19464279 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation		 EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [pentaacetyl geniposide results in increased phosphorylation of MAPK1 protein]; pentaacetyl geniposide results in decreased phosphorylation of and results in decreased activity of MAPK1 protein CTD PMID:17651887 PMID:19464279 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation		 EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [pentaacetyl geniposide results in increased phosphorylation of MAPK3 protein]; pentaacetyl geniposide results in decreased phosphorylation of and results in decreased activity of MAPK3 protein CTD PMID:17651887 PMID:19464279 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions
increases phosphorylation		 EXP pyrazolanthrone inhibits the reaction [pentaacetyl geniposide results in increased phosphorylation of MAPK8 protein] CTD PMID:17651887 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions
increases phosphorylation		 EXP pyrazolanthrone inhibits the reaction [pentaacetyl geniposide results in increased phosphorylation of MAPK9 protein] CTD PMID:17651887 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178 		JBrowse link
G Mmp14 matrix metallopeptidase 14 decreases expression EXP pentaacetyl geniposide results in decreased expression of MMP14 mRNA CTD PMID:19464279 NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864 		JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases activity
decreases expression		 EXP pentaacetyl geniposide results in decreased activity of MMP2 protein
pentaacetyl geniposide results in decreased expression of MMP2 mRNA		 CTD PMID:19464279 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Ngf nerve growth factor multiple interactions
increases expression		 EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [pentaacetyl geniposide results in increased expression of NGF mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [pentaacetyl geniposide results in increased expression of NGF protein]; Masoprocol inhibits the reaction [pentaacetyl geniposide results in increased expression of NGF mRNA]; Masoprocol inhibits the reaction [pentaacetyl geniposide results in increased expression of NGF protein]; pyrazolanthrone inhibits the reaction [pentaacetyl geniposide results in increased expression of NGF mRNA]; pyrazolanthrone inhibits the reaction [pentaacetyl geniposide results in increased expression of NGF protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [pentaacetyl geniposide results in increased expression of NGF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [pentaacetyl geniposide results in increased expression of NGF protein]; SB 203580 inhibits the reaction [pentaacetyl geniposide results in increased expression of NGF mRNA]; SB 203580 inhibits the reaction [pentaacetyl geniposide results in increased expression of NGF protein]
pentaacetyl geniposide results in increased expression of NGF mRNA; pentaacetyl geniposide results in increased expression of NGF protein		 CTD PMID:17651887 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Ngfr nerve growth factor receptor multiple interactions
increases expression		 EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [pentaacetyl geniposide results in increased expression of NGFR mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [pentaacetyl geniposide results in increased expression of NGFR protein]; Masoprocol inhibits the reaction [pentaacetyl geniposide results in increased expression of NGFR mRNA]; Masoprocol inhibits the reaction [pentaacetyl geniposide results in increased expression of NGFR protein]; pyrazolanthrone inhibits the reaction [pentaacetyl geniposide results in increased expression of NGFR mRNA]; pyrazolanthrone inhibits the reaction [pentaacetyl geniposide results in increased expression of NGFR protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [pentaacetyl geniposide results in increased expression of NGFR mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [pentaacetyl geniposide results in increased expression of NGFR protein]; SB 203580 inhibits the reaction [pentaacetyl geniposide results in increased expression of NGFR mRNA]; SB 203580 inhibits the reaction [pentaacetyl geniposide results in increased expression of NGFR protein]
pentaacetyl geniposide results in increased expression of NGFR mRNA; pentaacetyl geniposide results in increased expression of NGFR protein		 CTD PMID:17651887 NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518 		JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 increases expression EXP pentaacetyl geniposide results in increased expression of TIMP2 mRNA CTD PMID:19464279 NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19811
    chemical entity 19840
      atom 19809
        nonmetal atom 19747
          carbon atom 19734
            organic molecular entity 19705
              isoprenoid 14026
                terpenoid 13711
                  terpene glycoside 476
                    Geniposide pentaacetate 13
Path 2
Term Annotations click to browse term
  CHEBI ontology 19811
    subatomic particle 19809
      composite particle 19809
        hadron 19840
          baryon 19809
            nucleon 19809
              atomic nucleus 19809
                atom 19809
                  main group element atom 19759
                    p-block element atom 19759
                      carbon group element atom 19708
                        carbon atom 19734
                          organic molecular entity 19705
                            heteroorganic entity 19459
                              organochalcogen compound 19222
                                organooxygen compound 19137
                                  carbohydrates and carbohydrate derivatives 15269
                                    carbohydrate 15284
                                      carbohydrate derivative 14290
                                        glycosyl compound 13035
                                          glycoside 11816
                                            terpene glycoside 476
                                              Geniposide pentaacetate 13
paths to the root